CN112890820A - Interference identification circuit for electroencephalogram physiological signal acquisition and electronic equipment - Google Patents
Interference identification circuit for electroencephalogram physiological signal acquisition and electronic equipment Download PDFInfo
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7203—Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal
Abstract
The invention relates to an interference identification circuit for electroencephalogram physiological signal acquisition and electronic equipment, comprising a coupling ESD protection unit, a signal conditioning unit, a signal triggering unit and an interactive communication unit; the coupling ESD protection unit, the signal conditioning unit, the signal trigger unit and the interactive communication unit are sequentially connected in series. The invention can well perform bypass extraction on the interference signal in the input physiological signal, simultaneously avoids the influence on a normal physiological signal acquisition circuit, can convert and condition the interference signal, is triggered to generate the interference signal at high response speed, simultaneously triggers the response only to the signal with specific frequency, avoids the occurrence of false touch caused by other frequency band signals, responds to the whole circuit in time, has better anti-electromagnetic interference capability, and can monitor and respond to the interference signal in real time.
Description
Technical Field
The invention relates to the technical field of analog circuits, in particular to an interference identification circuit for electroencephalogram physiological signal acquisition and electronic equipment.
Background
In the actual electroencephalogram acquisition process in the operating room environment, various strong interference devices often introduce interference, and the strong interference signals can cause serious influence on electroencephalogram signal acquisition and are difficult to eliminate, such as strong electromagnetic interference generated by electrotome use, interference introduced by high-power lithotripsy devices and the like.
Interference signals in the electroencephalogram physiological signal acquisition process are processed in a few ways worldwide, and particularly strong interference signals are introduced to electrotome interference, ultrasonic equipment and ultrasonic knife equipment. In the prior art, a filter circuit and an interference leakage circuit are generally adopted to reduce the interference signal.
The inventor finds that at least the following problems exist in the prior art: the strength of interference signals can only be reduced so as to reduce the damage to a back end circuit, but the interference process cannot be further monitored and further processed, for example, a radiation protection circuit and a high-frequency filter circuit which are adopted in the electrocardio-electroencephalogram and electroencephalogram acquisition can only be used for reducing the strength of the interference signals generally, but the actual electroencephalogram physiological signals are very weak and are easily influenced by various interference signals, the common processing means cannot well process the interference, the processing means is single, and the identification and judgment of the interference are not sufficiently utilized.
Disclosure of Invention
In order to overcome the technical defects in the prior art, the invention provides an interference identification circuit and electronic equipment for acquiring electroencephalogram physiological signals, which can effectively solve the problems in the background art.
In order to solve the technical problems, the technical scheme provided by the invention is as follows:
the embodiment of the invention discloses an interference identification circuit for acquiring electroencephalogram physiological signals, which comprises a coupling ESD protection unit, a signal conditioning unit, a signal trigger unit and an interactive communication unit, wherein the coupling ESD protection unit is used for receiving an interference signal; the coupling ESD protection unit, the signal conditioning unit, the signal trigger unit and the interactive communication unit are sequentially connected in series; wherein:
the coupling ESD protection unit is used for acquiring an interference signal for an input physiological signal, discharging interference signal energy and protecting a back end circuit;
the signal conditioning unit is used for conditioning an interference signal;
the signal trigger unit is used for monitoring the interference signal in real time and responding to the trigger of the interference signal;
the interactive communication unit is used for denoising the triggered interference signal so as to reduce the interference influence of the interference signal in the electroencephalogram physiological signal.
In any of the above schemes, preferably, the signal conditioning unit includes a signal conditioning circuit, and the signal conditioning circuit includes a resistor R112, a resistor R113, and a transistor Q4; a first end of the resistor R112 is connected with a power supply, and a second end of the resistor R112 is connected with a base of the triode Q4; a first end of the resistor R113 is connected with a power supply, and a second end of the resistor R113 is connected with a collector of the triode Q4 in series and then connected with the signal triggering unit; the emitting electrode of the triode Q4 is connected with the ground; the resistor R113 is a collector series resistor of the transistor Q4, and is configured to adjust a collector current of the transistor Q4.
In any of the above schemes, preferably, the signal conditioning circuit further includes a resistor R114 and a transistor Q5; a first end of the resistor R114 is connected to a power supply, and a second end of the resistor R114 is connected to a collector of the transistor Q5 in series and then connected to the signal triggering unit; the base of the triode Q5 is connected with the collector of the triode Q4 and the second end of the resistor R113, and the emitter of the triode Q5 is connected with the ground; the resistor R114 is a series resistor on the collector of the transistor Q5, and is used for controlling the collector current and providing a pull-up resistance function.
In any of the above schemes, preferably, the coupling ESD protection unit includes a coupling circuit and an ESD protection circuit, the coupling circuit is connected in series with the ESD protection circuit, and the ESD protection circuit is connected in parallel with the signal conditioning circuit; the coupling circuit is used for acquiring an interference signal in an input physiological signal; the ESD protection circuit is used for suppressing electrostatic interference signals in the interference signals.
In any of the above schemes, preferably, the coupling circuit includes a coupling capacitor C145, a first end of the coupling capacitor C145 is connected to the signal conditioning circuit, and a second end of the coupling capacitor C145 is connected to the input physiological signal.
In any of the above solutions, it is preferable that the ESD protection circuit includes a transient voltage suppression diode Q6, an anode of the transient voltage suppression diode Q6 is connected to the first terminal of the coupling capacitor C145, the second terminal of the resistor R112, and the base of the transistor Q4, and a cathode of the transient voltage suppression diode Q6 is connected to ground.
In any of the above aspects, preferably, the signal trigger unit includes a signal trigger circuit, and the signal trigger circuit includes a flip-flop U33; the trigger U33 comprises a pin A, a pin B, a CLR pin, a GND pin, a pin Q, a pin Cext, a Rext/Cext pin and a VCC pin; the A pin is the 1 st end of the trigger U33, the B pin is the 2 nd end of the trigger U33, the CLR pin is the 3 rd end of the trigger U33, the GND pin is the 4 th end of the trigger U33, the Q pin is the 5 th end of the trigger U33, the Cext pin is the 6 th end of the trigger U33, the Rext/Cext pin is the 7 th end of the trigger U33, and the VCC pin is the 8 th end of the trigger U33.
In any of the above schemes, preferably, the 1 st terminal of the flip-flop U33 is connected to the collector of the transistor Q5 and the second terminal of the resistor R114, the 2 nd terminal and the 3 rd terminal of the flip-flop U33 are connected in parallel and then connected to a power supply, the 4 th terminal of the flip-flop U33 is connected to ground, and the 5 th terminal of the flip-flop U33 is connected to the interactive communication unit.
In any of the above schemes, preferably, the signal trigger circuit further includes a resistor R116 and a capacitor C146; the first terminal of the capacitor C146 is connected to the 6 th terminal of the flip-flop U33, the second terminal of the capacitor C146 is connected in parallel to the 7 th terminal of the flip-flop U33, the second terminal of the capacitor C146 is connected to the first terminal of the resistor R116, the second terminal of the resistor R116 is connected in series to the 8 th terminal of the flip-flop U33, and the second terminal of the resistor R116 is connected to a power supply.
An electronic device comprises the interference identification circuit for acquiring the electroencephalogram physiological signals.
Compared with the prior art, the invention has the beneficial effects that:
the interference recognition circuit and the electronic equipment for acquiring the electroencephalogram physiological signals can well perform bypass extraction on interference signals in input physiological signals through the coupling ESD protection unit, meanwhile, the influence on a normal physiological signal acquisition circuit is avoided, the interference signals can be well converted and conditioned through the signal conditioning unit to work in cooperation with the signal trigger unit, the interference signals can be triggered at a high response speed through the signal trigger unit, meanwhile, the response is triggered only on signals with specific frequencies, the occurrence of false touch caused by other frequency band signals is avoided, the response of the whole circuit is timely, the anti-electromagnetic interference capability is good, and the interference signals can be monitored and responded in real time.
Drawings
The drawings are included to provide a further understanding of the invention, and are incorporated in and constitute a part of this specification.
FIG. 1 is a block diagram of an interference identification circuit for electroencephalogram physiological signal acquisition according to the present invention;
fig. 2 is a specific structure circuit diagram of an interference identification circuit for electroencephalogram physiological signal acquisition.
The reference numbers in the figures illustrate:
100. coupling an ESD protection unit; 101. a coupling circuit; 102. an ESD protection circuit; 200. a signal conditioning unit; 201. a signal conditioning circuit; 300. a signal triggering unit; 301. a signal triggering circuit; 400. and an interactive communication unit.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is described in further detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.
It will be understood that when an element is referred to as being "secured to" or "disposed on" another element, it can be directly on the other element or be indirectly on the other element. When an element is referred to as being "connected to" another element, it can be directly connected to the other element or be indirectly connected to the other element.
In the description of the present invention, it is to be understood that the terms "length", "width", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", and the like, indicate orientations or positional relationships based on the orientations or positional relationships illustrated in the drawings, and are used merely for convenience in describing the present invention and for simplicity in description, and do not indicate or imply that the devices or elements referred to must have a particular orientation, be constructed in a particular orientation, and be operated, and thus, are not to be construed as limiting the present invention.
Furthermore, the terms "first", "second" and "first" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of the present invention, "a plurality" means two or more unless specifically defined otherwise.
For better understanding of the above technical solutions, the technical solutions of the present invention will be described in detail below with reference to the drawings and the detailed description of the present invention.
Example 1:
as shown in fig. 1, the present invention provides an interference identification circuit for electroencephalogram physiological signal acquisition, which includes a coupling ESD protection unit 100, a signal conditioning unit 200, a signal trigger unit 300, and an interactive communication unit 400; the coupling ESD protection unit 100, the signal conditioning unit 200, the signal triggering unit 300, and the interactive communication unit 400 are sequentially connected in series; wherein; the coupled ESD protection unit 100 is configured to obtain an interference signal for an input physiological signal, discharge interference signal energy, and protect a back end circuit; the signal conditioning unit 200 is configured to condition an interference signal; the signal trigger unit 300 is configured to monitor the interference signal in real time and respond to the trigger of the interference signal; the interactive communication unit 400 is configured to denoise the triggered interference signal to reduce the interference effect of the interference signal in the electroencephalogram physiological signal.
As shown in fig. 2, the signal conditioning unit 200 includes a signal conditioning circuit 201, where the signal conditioning circuit 201 includes a resistor R112, a resistor R113, and a transistor Q4; a first terminal of the resistor R112 is connected to a power supply, and a second terminal of the resistor R112 is connected to the base of the transistor Q4, so that the resistor R112 can be used to provide a base reference voltage of the transistor Q4; a first end of the resistor R113 is connected to a power supply, and a second end of the resistor R113 is connected to a collector of the transistor Q4 in series and then connected to the signal triggering unit 300; the emitting electrode of the triode Q4 is connected with the ground; the resistor R113 is a series resistor of a collector of the transistor Q4, and is mainly used for adjusting a collector current of the transistor Q4.
As shown in fig. 2, the signal conditioning circuit 201 further includes a resistor R114 and a transistor Q5; a first end of the resistor R114 is connected to a power supply, and a second end of the resistor R114 is connected to a collector of the transistor Q5 in series and then connected to the signal triggering unit 300; the base of the triode Q5 is connected with the collector of the triode Q4 and the second end of the resistor R113, and the emitter of the triode Q5 is connected with the ground; the resistor R114 is a series resistor on the collector of the transistor Q5, and is mainly used for controlling the collector current and providing a pull-up resistance function.
In a preferred embodiment, the signal conditioning circuit 201 may include one transistor, or may adopt a series structure of two transistors, and preferably, the signal conditioning circuit 201 adopts a series structure of two transistors, and by connecting the two transistors in series, it is able to better convert and condition the interference signal, so as to implement the matching with the following signal triggering circuit.
As shown in fig. 2, the coupled ESD protection unit 100 includes a coupling circuit 101 and an ESD protection circuit 102, the coupling circuit 101 is connected in series with the ESD protection circuit 102, and the ESD protection circuit 102 is connected in parallel with the signal conditioning circuit 201; the coupling circuit 101 is used for acquiring an interference signal in an input physiological signal; the ESD protection circuit 102 is used to suppress electrostatic interference signals in the interference signals.
As shown in fig. 2, the coupling circuit 101 includes a coupling capacitor C145, a first end of the coupling capacitor C145 is connected to the signal conditioning circuit 201, and a second end of the coupling capacitor C145 is connected to the input physiological signal.
As shown in fig. 2, the ESD protection circuit 102 includes a transient voltage suppression diode Q6, the anode of the transient voltage suppression diode Q6 is connected to the first terminal of the coupling capacitor C145, the second terminal of the resistor R112, and the base of the transistor Q4, and the cathode of the transient voltage suppression diode Q6 is connected to ground.
In a preferred embodiment, the coupling circuit 101 may be implemented by using a coupling capacitor C145, for example, a high-frequency ceramic capacitor with high voltage resistance, which can implement good bypass extraction of interference signals, and simultaneously avoid the influence on the normal physiological signal (e.g., electroencephalogram signal, etc.) acquisition circuit.
In a preferred embodiment, the ESD protection circuit may be implemented by using a transient voltage suppression diode, for example, a bidirectional transient voltage suppression diode, which can better suppress the electrostatic interference signal and avoid damage to the circuit.
As shown in fig. 2, the signal trigger unit 300 includes a signal trigger circuit 301, and the signal trigger circuit 301 includes a flip-flop U33; the trigger U33 comprises a pin A, a pin B, a CLR pin, a GND pin, a pin Q, a pin Cext, a Rext/Cext pin and a VCC pin; the A pin is the 1 st end of the trigger U33, the B pin is the 2 nd end of the trigger U33, the CLR pin is the 3 rd end of the trigger U33, the GND pin is the 4 th end of the trigger U33, the Q pin is the 5 th end of the trigger U33, the Cext pin is the 6 th end of the trigger U33, the Rext/Cext pin is the 7 th end of the trigger U33, and the VCC pin is the 8 th end of the trigger U33.
As shown in fig. 2, the 1 st terminal of the flip-flop U33 is connected to the collector of the transistor Q5 and the second terminal of the resistor R114, the 2 nd terminal and the 3 rd terminal of the flip-flop U33 are connected in parallel and then connected to a power supply, the 4 th terminal of the flip-flop U33 is connected to ground, and the 5 th terminal of the flip-flop U33 is connected to the interactive communication unit 400.
As shown in fig. 2, the signal trigger circuit 301 further includes a resistor R116 and a capacitor C146; the first end of the capacitor C146 is connected with the 6 th end of the trigger U33, the second end of the capacitor C146 is connected with the 7 th end of the trigger U33 in parallel and is connected with the first end of the resistor R116, and the second end of the resistor R116 is connected with the 8 th end of the trigger U33 in series and is connected with a power supply.
In a preferred embodiment, the trigger U33 of the signal trigger circuit 301 may adopt a schmitt trigger, so that the trigger U33 can be triggered to generate an interference signal at a higher response speed, and can monitor the response interference signal in real time.
In a preferred embodiment, the 1 st terminal of the flip-flop U33 is a falling edge input, the 2 nd terminal of the flip-flop U33 is a rising edge input, the 3 rd terminal of the flip-flop U33 is a rising edge input, the 4 th terminal of the flip-flop U33 is an output terminal, and when the 1 st terminal of the flip-flop U33 is used, the 2 nd terminal of the flip-flop U33 and the 3 rd terminal of the flip-flop U33 are connected with a 3V3 power supply to enable the flip-flop U33 to work normally; the 6 th end and the 7 th end of the trigger U33 are used for adjusting the trigger frequency and the response time of the interference signal, so that the trigger U33 only triggers the response to the signal with the specific frequency, and the false touch caused by other frequency band signals is avoided.
The interactive communication unit 400 is configured to denoise the triggered interference signal to reduce the interference effect of the interference signal in the electroencephalogram physiological signal, wherein the denoising of the triggered interference signal can be better achieved by a wavelet threshold denoising method.
Specifically, the wavelet coefficient obtained after wavelet transformation of the electroencephalogram physiological signal containing noise comprises the wavelet coefficient of an original signal and the wavelet coefficient of a noise signal, the wavelet coefficient of the electroencephalogram physiological signal which is usually input is often larger than the wavelet coefficient of the noise signal, the coefficient after wavelet decomposition can be compared with the threshold gamma by setting the threshold gamma, and if the coefficient after wavelet decomposition is smaller than the threshold gamma, the decomposition coefficient is considered to be caused by noise, and the partial signal is discarded; if the coefficient after wavelet decomposition is larger than the threshold value gamma, the decomposition coefficient is considered to be caused by the useful signal, and the part of the signal is reserved by using a soft threshold value method.
Further, by performing n-layer wavelet decomposition on the interference signal, the interference signal decomposition is expressed as S = cA1+cD1=cA2+cD2+cD1=…=cAn+cDn+…+cD2+cD1(ii) a Wherein, cAiAs low frequency part, cDiA high frequency part; the noise part is usually retained in the cDiIn by formula
To cDiProcessing the coefficients, reconstructing the wavelet through all the retained wavelet coefficients, and completing denoising; wherein the content of the first and second substances,
is paired with cDiThe coefficients after the noise removal are processed by the noise removal method,
is paired with cDiAnd (5) coefficients before denoising.
Example 2:
the invention also provides electronic equipment which comprises the interference identification circuit for electroencephalogram physiological signal acquisition in the embodiment 1.
The interference identification circuit and the electronic equipment for acquiring the electroencephalogram physiological signals have the beneficial effects that:
the interference recognition circuit and the electronic equipment for acquiring the electroencephalogram physiological signals can well perform bypass extraction on interference signals in input physiological signals through the coupling ESD protection unit 100, meanwhile, the influence on a normal physiological signal acquisition circuit is avoided, the interference signals can be well converted and conditioned through the signal conditioning unit 200 to work in cooperation with the signal trigger unit 300, the interference signals can be triggered at a high response speed through the signal trigger unit 300, meanwhile, the response is only triggered on signals with specific frequencies, the occurrence of false touch caused by other frequency band signals is avoided, the response is timely for the whole circuit, the anti-electromagnetic interference capability is good, and the interference signals can be monitored and responded in real time.
Although the present invention has been described in detail with reference to the foregoing embodiments, those skilled in the art will understand that various changes, modifications and substitutions can be made without departing from the spirit and scope of the invention as defined by the appended claims. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.
Claims (10)
1. An interference identification circuit for electroencephalogram physiological signal acquisition is characterized in that: the ESD protection circuit comprises a coupling ESD protection unit (100), a signal conditioning unit (200), a signal triggering unit (300) and an interactive communication unit (400); the coupling ESD protection unit (100), the signal conditioning unit (200), the signal trigger unit (300) and the interactive communication unit (400) are sequentially connected in series; wherein:
the coupling ESD protection unit (100) is used for acquiring an interference signal in an input physiological signal and discharging interference signal energy;
the signal conditioning unit (200) is used for conditioning an interference signal;
the signal trigger unit (300) is used for monitoring the interference signal in real time and responding to the trigger of the interference signal;
the interactive communication unit (400) is used for denoising the triggered interference signal so as to reduce the interference influence of the interference signal in the electroencephalogram physiological signal.
2. The interference identification circuit for brain electrical physiological signal acquisition of claim 1, characterized in that: the signal conditioning unit (200) comprises a signal conditioning circuit (201), wherein the signal conditioning circuit (201) comprises a resistor R112, a resistor R113 and a triode Q4; a first end of the resistor R112 is connected with a power supply, and a second end of the resistor R112 is connected with a base of the triode Q4; a first end of the resistor R113 is connected with a power supply, and a second end of the resistor R113 is connected with a collector of the triode Q4 in series and then connected with the signal triggering unit (300); the emitting electrode of the triode Q4 is connected with the ground; the resistor R113 is a collector series resistor of the transistor Q4, and is configured to adjust a collector current of the transistor Q4.
3. The interference identification circuit for brain electrical physiological signal acquisition of claim 2, characterized in that: the signal conditioning circuit (201) further comprises a resistor R114 and a triode Q5; a first end of the resistor R114 is connected with a power supply, and a second end of the resistor R114 is connected with a collector of the triode Q5 in series and then connected with the signal triggering unit (300); the base of the triode Q5 is connected with the collector of the triode Q4 and the second end of the resistor R113, and the emitter of the triode Q5 is connected with the ground; the resistor R114 is a series resistor on the collector of the transistor Q5, and is used for controlling the collector current.
4. The interference identification circuit for brain electrical physiological signal acquisition of claim 3, characterized in that: the coupled ESD protection unit (100) comprises a coupling circuit (101) and an ESD protection circuit (102), wherein the coupling circuit (101) is connected with the ESD protection circuit (102) in series, and the ESD protection circuit (102) is connected with the signal conditioning circuit (201) in parallel; wherein the coupling circuit (101) is used for acquiring an interference signal in the input physiological signal; the ESD protection circuit (102) is used for suppressing electrostatic interference signals in interference signals.
5. The interference identification circuit for brain electrical physiological signal acquisition of claim 4, characterized in that: the coupling circuit (101) comprises a coupling capacitor C145, a first end of the coupling capacitor C145 is connected with the signal conditioning circuit (201), and a second end of the coupling capacitor C145 is connected with the input physiological signal.
6. The interference identification circuit for brain electrical physiological signal acquisition of claim 5, characterized in that: the ESD protection circuit (102) includes a transient voltage suppression diode Q6, an anode of the transient voltage suppression diode Q6 is connected to the first terminal of the coupling capacitor C145, the second terminal of the resistor R112, and the base of the transistor Q4, and a cathode of the transient voltage suppression diode Q6 is connected to ground.
7. The interference identification circuit for brain electrical physiological signal acquisition of claim 6, characterized by: the signal trigger unit (300) comprises a signal trigger circuit (301), wherein the signal trigger circuit (301) comprises a trigger U33; the trigger U33 comprises a pin A, a pin B, a CLR pin, a GND pin, a pin Q, a pin Cext, a Rext/Cext pin and a VCC pin; the A pin is the 1 st end of the trigger U33, the B pin is the 2 nd end of the trigger U33, the CLR pin is the 3 rd end of the trigger U33, the GND pin is the 4 th end of the trigger U33, the Q pin is the 5 th end of the trigger U33, the Cext pin is the 6 th end of the trigger U33, the Rext/Cext pin is the 7 th end of the trigger U33, and the VCC pin is the 8 th end of the trigger U33.
8. The interference identification circuit for electroencephalogram physiological signal acquisition of claim 7, wherein: the 1 st end of the trigger U33 is connected with the collector of the triode Q5 and the second end of the resistor R114, the 2 nd end and the 3 rd end of the trigger U33 are connected in parallel and then connected with a power supply, the 4 th end of the trigger U33 is connected with the ground, and the 5 th end of the trigger U33 is connected with the interactive communication unit (400).
9. The interference identification circuit for brain electrical physiological signal acquisition of claim 8, characterized in that: the signal trigger circuit (301) further comprises a resistor R116 and a capacitor C146; the first terminal of the capacitor C146 is connected to the 6 th terminal of the flip-flop U33, the second terminal of the capacitor C146 is connected in parallel to the 7 th terminal of the flip-flop U33, the second terminal of the capacitor C146 is connected to the first terminal of the resistor R116, the second terminal of the resistor R116 is connected in series to the 8 th terminal of the flip-flop U33, and the second terminal of the resistor R116 is connected to a power supply.
10. An electronic device, characterized in that: an interference identification circuit for brain electrical physiological signal acquisition comprising any one of claims 1 to 9.
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Application publication date: 20210604 |
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