CN112879273A - Implantable body fluid transport pump and pump system for directional transport of body fluid - Google Patents
Implantable body fluid transport pump and pump system for directional transport of body fluid Download PDFInfo
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- CN112879273A CN112879273A CN202110007096.4A CN202110007096A CN112879273A CN 112879273 A CN112879273 A CN 112879273A CN 202110007096 A CN202110007096 A CN 202110007096A CN 112879273 A CN112879273 A CN 112879273A
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Images
Classifications
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B43/00—Machines, pumps, or pumping installations having flexible working members
- F04B43/02—Machines, pumps, or pumping installations having flexible working members having plate-like flexible members, e.g. diaphragms
- F04B43/04—Pumps having electric drive
- F04B43/043—Micropumps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M27/00—Drainage appliance for wounds or the like, i.e. wound drains, implanted drains
- A61M27/002—Implant devices for drainage of body fluids from one part of the body to another
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B43/00—Machines, pumps, or pumping installations having flexible working members
- F04B43/0009—Special features
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B43/00—Machines, pumps, or pumping installations having flexible working members
- F04B43/0009—Special features
- F04B43/0054—Special features particularities of the flexible members
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B43/00—Machines, pumps, or pumping installations having flexible working members
- F04B43/0009—Special features
- F04B43/0081—Special features systems, control, safety measures
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B51/00—Testing machines, pumps, or pumping installations
Abstract
The invention discloses an implanted body fluid transportation pump and a pump system for directional transportation of body fluid, wherein the implanted body fluid transportation pump comprises a pump body and a drive control assembly, the pump body comprises a bottom plate, a top plate and a side wall arranged between the bottom plate and the top plate, the bottom plate, the top plate and the side wall jointly form a containing cavity, a liquid inlet and a liquid outlet communicated with the containing cavity are formed in the side wall, at least one of the bottom plate and the top plate is a magnetic flexible film, the drive control assembly comprises a magnetic field generator, the magnetic field generator can emit a variable magnetic field, the drive control assembly can control the magnetic flexible film to move back and forth in a direction close to or far away from the drive control assembly through the magnetic field generator, and the volume of the containing cavity can be. The magnetic field generator drives the pump body to transport liquid through magnetic force, so that the circulation of body fluid is effectively ensured, and the edema of the body is avoided. And the pump body has simple structure and small volume, and is more beneficial to being implanted into the body of a patient.
Description
Technical Field
The invention relates to the technical field of medical instruments, in particular to an implantable body fluid transportation pump and a pump system for directional transportation of body fluid.
Background
Edema has various adverse effects on the body and can also cause organ dysfunction, for example, gastrointestinal mucosa edema can affect digestion and absorption, pulmonary edema can cause respiratory dysfunction, pericardial hydrops can affect the function of heart pumping, laryngeal edema can cause airway obstruction and even asphyxia, cerebral edema can cause intracranial pressure rise and even form cerebral hernia, thereby endangering life.
Lymphedema is only one of the tissue edemas. Edema can result when interstitial fluid production exceeds reflux. Edema can occur locally, such as pulmonary edema, cerebral edema; it also can affect the whole body, called systemic edema, such as cardiac edema in congestive heart failure, renal edema in renal disease or nephritis, hepatic edema in liver disease, etc.; the other systemic edema is not known for the present time and is called "idiopathic edema".
Lymphedema is a highly disabled disease, the 11 th place is the lymphedema in the ranks of common diseases in the world health organization, the 2 nd place is the disabled disease, and the number of patients in the world is about 1.7 hundred million, wherein the number of the patients in the lymphedema in China is nearly ten million. Any surgical procedure requiring the removal of regional lymph nodes or vessels can lead to lymphedema. For example, patients who receive breast cancer, gynecological tumors, male genitourinary tumor operations and radiotherapy have a lymphedema ratio of up to 10-60% after the operation of the operation; the lymphedema rate of breast cancer survivors is 15-30%; secondary lower limb lymphedema occurs in 28% -47% of patients with gynecological cancer after treatment. Lymphedema can occur within 3 weeks to 30 years after surgery in a patient.
Lymphedema is a worldwide medical problem, which is not curable at present, and most patients cannot be effectively diagnosed and treated after the disease occurs, so that the disease condition is worsened continuously. Lymphedema often accompanies symptoms such as limited limb function, pain, fatigue, anxiety, and the like, which seriously affect the mind, body function, social function, and quality of life of the patient. In the past, due to the insufficient understanding on lymphedema, active comprehensive intervention is replaced by passive single conservative treatment, if the treatment is not timely and correctly carried out, ulcer, frequent lymphatics and surrounding tissue inflammation (erysipelas and cellulitis), affected limb dysfunction, limb or organ deformity and even disability, and malignant lesions such as lymphatics/vascular endothelial sarcoma and the like can be caused, and each infection can aggravate edema to form malignant circulation, which seriously influences the life quality of patients.
At present, the conservative treatment methods of lymphedema include manual drainage Comprehensive Detumescence (CDT) treatment, far infrared thermotherapy, intermittent air pressure treatment, drug therapy and the like. The operation treatment comprises lesion tissue resection, micro lymph bypass operation, negative pressure liposuction/suction operation, lymph reflux reconstruction operation and the like, most of lymphedema patients do not need to be treated by surgical operation, the existing operation methods can not cure the lymphedema except amputation operation, and the symptoms can be improved only in a short time. Among them, the tissue lesion excision is a very traumatic operation, and although the operation removes the hyperplastic lesion tissue, the operation also destroys the residual lymphatic vessels and blood vessels, so that the replanted skin is extremely poor in nutrition and serious in complications. The suction has good volume reduction effect and few complications. However, postoperative patients may wear pressure cuffs for a lifetime to maintain the surgical effect, and often only advanced patients are subjected to aspiration of diseased tissue.
Therefore, an auxiliary medical apparatus capable of realizing directional body fluid transportation is urgently needed.
Disclosure of Invention
In order to overcome the defects and shortcomings in the prior art, the invention aims to provide an implantable body fluid transportation pump and a pump system for directional transportation of body fluid, so as to solve the problem of body edema caused by abnormal circulation of body fluid in the prior art.
The purpose of the invention is realized by the following technical scheme:
the invention provides an implantable body fluid transportation pump which comprises a pump body and a drive control assembly, wherein the pump body comprises a bottom plate, a top plate and a side wall arranged between the bottom plate and the top plate, the bottom plate, the top plate and the side wall jointly form an accommodating cavity, a liquid inlet and a liquid outlet communicated with the accommodating cavity are formed in the side wall, at least one of the bottom plate and the top plate is a magnetic flexible film, the drive control assembly comprises a magnetic field generator, the magnetic field generator can emit a variable magnetic field, the drive control assembly can control the magnetic flexible film to move back and forth in a direction close to or far away from the drive control assembly through the magnetic field generator, and the magnetic flexible film can change the volume of the accommodating cavity in the variable magnetic field.
Further, the bottom plate and the top plate are both magnetic flexible films, the magnetic poles of the bottom plate are opposite to the magnetic poles of the top plate, and the moving directions of the bottom plate and the top plate in the same magnetic field are opposite.
Furthermore, the implanted body fluid transport pump further comprises at least two one-way valves, the conduction directions of all the one-way valves are the same, and the one-way valves are used for controlling the liquid to flow from the liquid inlet to the liquid outlet.
Further, at least one of the one-way valves is located upstream and downstream of the pump body.
Further, the check valve is arranged in the pump body, and the check valve is arranged at the liquid inlet and/or the liquid outlet.
Further, the check valve comprises a valve, a valve support and a valve wall, the number of the valve is at least two, one end of the valve is fixed on the valve wall through the valve support, the other end of the valve is in contact with the center of the valve support and can be opened or closed according to the hydraulic pressure difference of two sides of the valve.
Further, the valve is of a fan-shaped structure, and the arc edge of the valve is connected with the valve support.
Further, the thickness of the valve near the center of the valve holder is thicker relative to the thickness of the middle portion of the valve.
Further, the valve is made of polyurethane, PEEK or silica gel.
Further, drive control assembly still includes treater, battery and wireless communicator, magnetic field generator the battery and wireless communicator all with treater electric connection, the battery be used for giving drive control assembly supplies power, wireless communicator is used for transmitting wireless signal, the treater is used for controlling magnetic field generator sends the magnetic field of change.
Further, the drive control assembly further comprises a flow sensor, the flow sensor is electrically connected with the processor, and the flow sensor is used for detecting the liquid flow of the pump body.
Further, the number of the pump bodies is multiple, and the multiple pump bodies are connected in series or/and in parallel.
Further, implanted body fluid transportation pump still includes the protective housing, the pump body is located in the protective housing, the surface of protective housing is coarse structure or helicitic texture.
The invention also provides a pump system for directional transportation of body fluid, which comprises the implanted body fluid transportation pump, the pump body is implanted in the body of a patient, and the drive control assembly is worn outside the body of the patient and corresponds to the pump body.
The invention has the beneficial effects that: implantable body fluid transportation pump includes the pump body and drive control assembly, the pump body includes the bottom plate, the roof and locate the lateral wall between bottom plate and the roof, the bottom plate, roof and lateral wall form jointly and hold the chamber, be equipped with on the lateral wall and hold inlet and the liquid outlet of chamber intercommunication, at least one of them is the flexible membrane of magnetism of bottom plate and roof, drive control assembly includes magnetic field generator, magnetic field generator can send the magnetic field that changes, drive control assembly can control the flexible membrane of magnetism and be close to or keep away from drive control assembly's direction back and forth movement through magnetic field generator, the flexible membrane of magnetism can change the volume that holds the chamber in the magnetic field that changes. The magnetic field generator drives the pump body to transport liquid through magnetic force, so that the circulation of body fluid is effectively ensured, and the edema of the body is avoided. And the pump body has simple structure and small volume, and is more beneficial to being implanted into the body of a patient.
Drawings
FIG. 1 is a schematic diagram of a pump system for directional transport of body fluids according to the present invention;
FIG. 2 is a schematic diagram of an implantable fluid delivery pump according to the present invention;
FIG. 3 is a schematic structural view of an implantable fluid transport pump of the present invention in an expanded state;
FIG. 4 is a schematic structural diagram of an implantable fluid transport pump of the present invention in a contracted state;
FIG. 5 is a schematic view of the construction of the check valve of the present invention;
FIG. 6 is a schematic view of a one-way valve of the present invention in a disassembled configuration;
FIG. 7 is a schematic view of the structure of the drive control assembly of the present invention;
FIG. 8 is a block diagram showing the construction of a drive control unit according to the present invention;
fig. 9 is a schematic diagram of a pump system for directional transport of bodily fluids according to another embodiment of the present invention.
Detailed Description
To further illustrate the technical means and effects of the present invention adopted to achieve the predetermined objects, the following detailed description will be made of specific embodiments, structures, features and effects of an implantable fluid transport pump and a pump system for directional transport of body fluid according to the present invention with reference to the accompanying drawings and preferred embodiments:
fig. 1 is a schematic structural diagram of a pump system for directional transportation of body fluid according to the present invention, fig. 2 is a schematic structural diagram of an implantable body fluid transport pump according to the present invention, fig. 3 is a schematic structural diagram of an implantable body fluid transport pump according to the present invention in an expanded state, fig. 4 is a schematic structural diagram of an implantable body fluid transport pump according to the present invention in a contracted state, fig. 5 is a schematic structural diagram of a check valve according to the present invention, fig. 6 is a schematic structural diagram of a check valve according to the present invention, fig. 7 is a schematic structural diagram of a drive control assembly according to the present invention.
As shown in fig. 1 to 8, the present invention provides a pump system for directional transportation of body fluid, which comprises an implantable body fluid transportation pump, a pump body 10 implanted in a patient, and a drive control assembly 20 worn outside the patient and corresponding to the pump body 10. As shown in fig. 1, the pump body 10 is in communication with blood vessel 2 and lymphatic vessel 3, or blood vessel 2 and lymph nodes, via a conduit 40 for transporting lymph fluid into blood vessel 2, reestablishing lymphatic pathways, and inhibiting further lymphedema. Wherein, skin 1 inboard is the internal of patient, and skin 1 outside is the external of patient, and the drive control subassembly 20 of wearing in vitro drives the pump body 10 through magnetic field, does not introduce power and coil or complicated circuit to the pump body 10 need not to carry battery and coil certainly and also can transport body fluid. Of course, the pump system for the directed transport of body fluids may also be used for the transport of other body fluids, not limited to lymph fluids.
As shown in fig. 1-4, the implantable body fluid transportation pump includes a pump body 10 and a driving control assembly 20, the pump body 10 includes a bottom plate 11, a top plate 12 and a side wall 13 disposed between the bottom plate 11 and the top plate 12, the bottom plate 11, the top plate 12 and the side wall 13 together form an accommodating cavity 101, the side wall 13 is provided with a liquid inlet 131 and a liquid outlet 132 communicated with the accommodating cavity 101, at least one of the bottom plate 11 and the top plate 12 is a magnetic flexible film, the driving control assembly 20 includes a magnetic field generator 21, the magnetic field generator 21 can emit a changing magnetic field, the driving control assembly 20 can control the magnetic flexible film to move back and forth in a direction close to or far away from the driving control assembly 20 through the magnetic field generator 21, and the magnetic flexible film can change the volume of the accommodating.
The magnetic flexible film can be made of a magnetic flexible colloid material, the magnetic flexible film can be made of a magnetic material with a middle layer encapsulated by two layers of flexible biocompatible materials, and the magnetic material can be a magnetic film or a magnetic block with a certain size and shape. For example, the flexible biocompatible material is silica gel, magnetic powder or magnetic blocks can be added into the silica gel, and then the silica gel is magnetized, so that the magnetic pole direction of the magnetic flexible film is perpendicular to the surface of the magnetic flexible film, and the magnetic film can operate under the influence of magnetic force in a magnetic field. The magnetic field generator 21 is preferably a magnetic field coil, and the direction and magnitude of the magnetic field generated by the magnetic field generator 21 are controlled by controlling the current applied to the magnetic field coil. Of course, the magnetic field generator 21 may be a magnet, which is then driven to flip by a driving mechanism to change the direction of the magnetic field, or a driving mechanism to reciprocate the magnet in a direction away from or toward the pump body 10. Through different magnetic field effects and timing sequence designs, different drainage and derivation effects can further be achieved by the pump body 10.
In this embodiment, the bottom plate 11 and the top plate 12 are both magnetic flexible films, and the magnetic poles of the bottom plate 11 are opposite to the magnetic poles of the top plate 12, that is, the magnetic poles on the opposite sides of the bottom plate 11 and the top plate 12 are the same, so that the moving directions of the bottom plate 11 and the top plate 12 in the same magnetic field are opposite. Of course, in other embodiments, a magnetic flexible film may be used for the bottom plate 11 or the top plate 12, only the volume change of the accommodating cavity 101 is reduced, so that the power of the pump body 10 is reduced.
As shown in fig. 3, when the magnetic field generator 21 generates the first magnetic field, the bottom plate 11 moves away from the driving control assembly 20, the top plate 12 moves closer to the driving control assembly 20, the volume of the accommodating chamber 101 increases, and the body fluid is sucked into the accommodating chamber 101 from the fluid inlet 131; as shown in fig. 4, when the magnetic field generator 21 generates the second magnetic field, the first magnetic field and the second magnetic field are opposite in direction, the bottom plate 11 moves in a direction approaching the drive control assembly 20, the top plate 12 moves in a direction away from the drive control assembly 20, the volume of the containing chamber 101 is reduced, and the body fluid is discharged from the liquid outlet 132, so that the body fluid is driven to move by one contraction of the containing chamber 101. Specifically, under the strong action of an external magnetic field, when the drive control assembly 20 and the top plate 12 have opposite magnetic poles, an attraction effect occurs between the two, the flexible top plate 12 protrudes towards the outside of the skin 1, on the contrary, the bottom plate 11 also expands towards the outside of the cavity under the opposite repulsion effect, the internal pressure of the whole pump body 10 is reduced due to the expansion state, and the filling and drainage of liquid into the cavity are realized; when the drive control assembly 20 and the top plate 12 have the same magnetic poles, the two magnetic poles repel each other, the flexible top plate 12 is recessed towards the inside of the cavity, otherwise, the bottom plate 11 is also retracted towards the inside due to the opposite suction force, and the whole pump body 10 is in a retracted state, so that the internal pressure is increased, and the liquid in the cavity is squeezed out. Reciprocating in this way, the magnetic field generator 21 realizes continuous flow guiding work of the pump body 10 under certain current waveform and frequency.
In the present embodiment, the number of the pump bodies 10 is one. In other embodiments, the number of the pump bodies 10 may be plural, and the plural pump bodies 10 are connected in series or/and in parallel with each other. As shown in fig. 9, the number of the pump bodies 10 is four, the four pump bodies 10 are connected in series, the transport capacity of the implantable transfer pump is improved by arranging the pump bodies 10 in series within a certain range, and the transverse volume is reduced, so that the power of the pump system for directional transport of body fluid for transporting body fluid is improved.
Further, the implantable fluid transport pump further comprises at least two one-way valves 30, all the one-way valves 30 are conducted in the same direction, and the one-way valves 30 are used for controlling the liquid to flow from the liquid inlet 131 to the liquid outlet 132. One-way flow of liquid is controlled by one-way valve 30. In other embodiments, such as where the vessel itself has a biological valve, which may act as a one-way valve, the need for a one-way valve 30 is eliminated, reducing the number of devices implanted in the patient and the difficulty and risk of the procedure.
Further, at least one check valve 30 is located upstream and downstream of the pump body 10, that is, at least one check valve 30 is disposed upstream of the pump body 10, at least one check valve 30 is disposed downstream of the pump body 10, for example, one check valve 30 is disposed at the most upstream and the most downstream of the pump body 10, respectively, and a check valve 30 may be disposed between two pump bodies 10 connected in series, so as to ensure that when the body fluid conduit itself has no biological valve, the one-way flow of the fluid can be controlled. The upstream and downstream are in terms of the liquid flow direction, and the liquid inlet 131 of the pump body 10 is located above the upstream of the pump body 10, and the liquid outlet 132 is located below the downstream of the pump body 10. In this embodiment, one check valve 30 is disposed upstream and downstream of the pump body 10, wherein two ends of one check valve 30 are respectively communicated with the blood vessel 2 and the pump body 10 through the conduit 40, and two ends of the other check valve 30 are respectively communicated with the lymph node and the pump body 10 through the conduit 40. Of course, in other embodiments, the one-way valve 30 may be disposed in the pump body 10, and the one-way valve 30 may be disposed at the inlet 131 and/or the outlet 132, so as to reduce the number of devices implanted in the patient and reduce the difficulty and risk of the operation.
Further, as shown in fig. 5 and 6, the check valve 30 includes a valve 31, a valve holder 32, and a valve wall 33, the valve wall 33 is a tubular structure, the valve holder 32 is an annular structure and is engaged with an inner wall of the valve wall 33, the valve 31 has at least two pieces, one end of the valve 31 is fixed on the inner wall of the valve wall 33 by the valve holder 32, and the other end of the valve 31 is contacted at the center of the valve holder 32 and can open or close the check valve 30 according to a hydraulic pressure difference between both sides of the valve 31. In this embodiment, the number of the valve 31 is at least three, the valve 31 is a fan-shaped structure, and the arc edge of the valve 31 is connected with the valve support 32. The valve holder 32 functions to fix the valve 31 while limiting the open-close condition and open-close angle of the valve 31; the valve 31 component is a double-leaf valve or a three-leaf valve consisting of 2-3 single-piece valves, and is opened when the inner side of the valve is pressed to a certain degree by utilizing the flexible design of the valve 31 component, the opening pressure is lower, and the reverse pressing of the outer side of the valve 31 is higher when liquid flows backwards, so that the valve is closed and is not stopped; the valve wall 33 is typically a relatively hard metal material that provides support and protection. The design scheme of the valve type one-way valve 30 similar to a heart valve structure, the valve 31 and the valve support 32 which are main components of the bionic one-way valve 30 are both flexible elastomers, the valve support 32 can be better and directly filled into the valve wall 33 and completely attached by utilizing the elastic property of the valve support, and the valve support 32 has certain strength to play a role in supporting and fixing and is mainly made of silicon rubber materials; the three-leaf valve 31 forms a three-leaf valve component, and based on material performance, the size and thickness of each valve are designed into a cambered surface structure according to a certain design, so that certain unidirectional flow guiding and sufficient reverse non-return effects are ensured. Meanwhile, due to the flexible structure design, the valve 31 and the valve stent 32 can be directly and integrally designed with the catheter 40, that is, the wall of the catheter 40 is used as the valve wall 33, and the valve 31 and the valve stent 32 are directly arranged on the wall of the catheter 40.
Further, the thickness of the valve 31 near the center of the valve holder 32 is thicker relative to the thickness of the middle portion of the valve 31. Namely, the thickness of the tip of the single valve 31 is slightly thicker than that of the middle part, and the tail end needs to realize the fixing and opening and closing effects of the valve 31 through the design control of certain thickness, structure and angle. The valve 31 can be calculated and tested in practical application to further optimize the microstructure and material performance requirements, thereby better realizing the function of the one-way valve. Meanwhile, the fluid dynamics change brought by the diversion of the drive control assembly 20 and the pump body is combined, so that the liquid diversion can be carried out more stably and controllably.
Further, the material used for the valve 31 may be polyurethane, PEEK, or silicone. Preferably, the valve 21 of the one-way valve 30 and the catheter 40 and the pump body 10 are made of the same biocompatible material (e.g., polyurethane, PEEK, silicone, etc.), so that they are susceptible to a certain degree of resonance when the pump body 10 vibrates, thereby achieving a synergistic amplification of the "opening" or "closing" function of the one-way valve.
Further, the implantable body fluid transport pump further includes a protective casing (not shown), the pump body 10 is disposed in the protective casing, and an outer surface of the protective casing is a rough structure or a threaded structure. The hardness of the protective shell is harder than that of the pump body 10, so that interference caused by tissue extrusion is prevented, but the protective shell cannot be made of metal materials, so that interference on driving of the pump body 10 is avoided. The surface of the outermost layer of the protective shell is rough or threaded, the specific surface area is increased, the fixation of the pump is facilitated, and the influence of the relative displacement on magnetic field coupling and equipment operation is prevented.
Further, as shown in fig. 7 and 8, the driving control assembly 20 further includes a processor 22, a battery 23, and a wireless communicator 24, the magnetic field generator 21, the battery 23, and the wireless communicator 24 are all electrically connected to the processor 22, the battery 23 is used for supplying power to the driving control assembly 20, the wireless communicator 24 is used for transmitting a wireless signal, and the processor 22 is used for controlling the magnetic field generator 21 to emit a changing magnetic field. Wherein, wireless communication ware 24 is for example the bluetooth, wireless network and NFC etc, drive control assembly 20 can carry out signal connection with mobile device (cell-phone, computer etc.) through wireless communication ware 24, thereby the patient can control drive control assembly 20 through mobile device's APP and exert current for magnetic field generator 21, then the size of current input through time sequence design regulation and control magnetic field generator 21, the direction, the wave form, frequency isoparametric, can regulate and control magnetic field generator 21 and produce intensity and the information in magnetic field, and then regulate and control the internal liquid of implanting the pump body under magnetic field and lead in and flow out work, satisfy different body fluid transportation effect demands.
Further, the driving control assembly 20 further includes a flow sensor 25, the flow sensor 25 is electrically connected to the processor 22, and the flow sensor 25 is used for detecting the liquid flow rate of the pump body 10. When the body fluid transportation data of the pump body 10 in the body is acquired through the series of flexible micro sensors (flow sensors 25), the tissue edema or lymphedema and body fluid transportation conditions of a patient can be further monitored intelligently, so that the transportation parameter setting of the micro pump system is adjusted and optimized continuously, and the function closed loop is realized.
Further, the driving control assembly 20 further includes an encapsulating housing 26, the encapsulating housing 26 is made of a flexible material to have a better wearable advantage, and the magnetic field generator 21, the processor 22, the battery 23, the wireless communicator 24 and the flow sensor 25 are all enclosed in the encapsulating housing 26. Of course, the driving control assembly 20 may also be provided with a display screen to display the working state of the driving control assembly 20.
The following notes and procedures in the surgery are given as references:
sterilizing all devices of a pump system for directional transportation of body fluid, positioning and surgically implanting the pump body 10, the one-way valve 30 and the catheter 40, wherein the catheter 40 positioned at the upstream of the pump body 10 is connected to a lymph duct or lymph node position of an affected area, and a catheter 40 interface positioned at the downstream of the pump body 10 flows to veins;
then confirming that the wound is recovered and the immune reaction in the body is normal, wearing and fixing the drive control assembly 20 outside the body to enable the drive control assembly 20 to correspond to the pump body 10;
initializing the system, confirming that the data transmission of the APP on the drive control component 20 and the mobile device is normal, and inputting individual customized medical parameters;
then starting the pump body 10, and starting the pump system to operate;
the real-time state of lymph fluid transportation can be further tracked by introducing sensors to the pump body 10, the catheter 40 or the drive control assembly 20 part for monitoring the flow speed and the flow, and transmitting related data signals to APP for calculation and analysis, and the treatment state tracking of lymphedema is assisted;
when the physiological immune response brought by the implant in vivo is too large to influence the operation of the micropump or influence the physiological health, the system is taken out through an operation after the service life is ended, the work of each part assembly is stopped, and the diagnosis and recovery are carried out in time when the physiology is abnormal.
The invention designs the magnetic flexible membrane to output an implantable liquid micropump, and utilizes an external magnetic driver (a driving control component 20) to drive the magnetic flexible membrane to move, and the driving control component 20 has better wearable advantage, and meanwhile, the implanted part can intelligently and effectively work and feed back while reducing the biological immunity, and does not destroy lymphatic tissues and blood vessels in a human body, thereby greatly reducing the occurrence probability of postoperative recurrence and complications. Different from conservative treatment, the invention can work quickly after implantation to take effect, is more beneficial to monitoring the state of an illness and the treatment effect through intelligent sensing and monitoring, and provides a more universal treatment approach for tissue edema, particularly lymphedema.
In this document, the terms of upper, lower, left, right, front, rear and the like are used to define the positions of the structures in the drawings and the positions of the structures relative to each other, and are only used for the sake of clarity and convenience in technical solution. It is to be understood that the use of the directional terms should not be taken to limit the scope of the claims. It is also to be understood that the terms "first" and "second," etc., are used herein for descriptive purposes only and are not to be construed as limiting in number or order.
Although the present invention has been described with reference to the preferred embodiments, it should be understood that various changes, substitutions and alterations can be made herein without departing from the spirit and scope of the invention as defined by the appended claims.
Claims (14)
1. The implantable body fluid transportation pump is characterized by comprising a pump body (10) and a drive control assembly (20), wherein the pump body (10) comprises a bottom plate (11), a top plate (12) and a side wall (13) arranged between the bottom plate (11) and the top plate (12), the bottom plate (11), the top plate (12) and the side wall (13) jointly form a containing cavity (101), a liquid inlet (131) and a liquid outlet (132) communicated with the containing cavity (101) are formed in the side wall (13), at least one of the bottom plate (11) and the top plate (12) is a magnetic flexible film, the drive control assembly (20) comprises a magnetic field generator (21), the magnetic field generator (21) can emit a variable magnetic field, and the drive control assembly (20) can control the magnetic flexible film to move back and forth in a direction close to or far away from the drive control assembly (20) through the magnetic field generator (21), the magnetically flexible membrane is capable of changing the volume of the receiving cavity (101) in a changing magnetic field.
2. The implantable fluid transport pump according to claim 1, wherein the bottom plate (11) and the top plate (12) are both magnetic flexible films, the magnetic poles of the bottom plate (11) are opposite to the magnetic poles of the top plate (12), and the moving directions of the bottom plate (11) and the top plate (12) in the same magnetic field are opposite.
3. The implantable fluid transport pump according to claim 1, further comprising at least two one-way valves (30), all of the one-way valves (30) having the same conducting direction, the one-way valves (30) being configured to control the flow of liquid from the liquid inlet (131) to the liquid outlet (132).
4. The implantable bodily fluid transport pump of claim 3, wherein at least one of the one-way valves (30) is located upstream and downstream of the pump body (10).
5. The implantable fluid transport pump according to claim 3, wherein the one-way valve (30) is provided within the pump body (10), the one-way valve (30) being provided at the inlet (131) and/or at the outlet (132).
6. The implantable body fluid transport pump according to claim 3, wherein the one-way valve (30) comprises a valve (31), a valve holder (32) and a valve wall (33), the number of the valve (31) is at least two, one end of the valve (31) is fixed on the valve wall (33) by the valve holder (32), and the other end of the valve (31) is contacted at the center of the valve holder (32) and can open or close the one-way valve (30) according to the hydraulic pressure difference on both sides of the valve (31).
7. The implantable fluid transport pump of claim 6, wherein the valve (31) is a fan-shaped structure, the arc sides of the valve (31) being connected to the valve holder (32).
8. The implantable bodily fluid transport pump of claim 7, wherein a thickness of the valve (31) near a center of the valve holder (32) is thicker relative to a thickness of a middle portion of the valve (31).
9. The implantable fluid transport pump of claim 6, wherein the valve (31) is made of polyurethane, PEEK or silicone.
10. The implantable bodily fluid transport pump of claim 1, wherein the drive control assembly (20) further comprises a processor (22), a battery (23), and a wireless communicator (24), the magnetic field generator (21), the battery (23), and the wireless communicator (24) are all electrically connected to the processor (22), the battery (23) is used to power the drive control assembly (20), the wireless communicator (24) is used to transmit a wireless signal, and the processor (22) is used to control the magnetic field generator (21) to emit a changing magnetic field.
11. The implantable fluid transport pump of claim 10, wherein the drive control assembly (20) further comprises a flow sensor (25), the flow sensor (25) being electrically connected to the processor (22), the flow sensor (25) being configured to detect a fluid flow rate of the pump body (10).
12. The implantable body fluid transport pump according to claim 1, wherein the number of the pump bodies (10) is plural, and the plural pump bodies (10) are connected in series or/and in parallel with each other.
13. The implantable body fluid transport pump according to claim 1, further comprising a protective shell, wherein the pump body (10) is disposed in the protective shell, and an outer surface of the protective shell is of a rough structure or a threaded structure.
14. A pump system for the directional transport of body fluids, comprising an implantable body fluid transport pump according to any one of claims 1 to 13, the pump body (10) being implanted in the body of a patient, the drive control assembly (20) being worn outside the body of the patient and corresponding to the pump body (10).
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| CN202110007096.4A CN112879273A (en) | 2021-01-05 | 2021-01-05 | Implantable body fluid transport pump and pump system for directional transport of body fluid |
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| CN202110007096.4A CN112879273A (en) | 2021-01-05 | 2021-01-05 | Implantable body fluid transport pump and pump system for directional transport of body fluid |
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| CN202110007096.4A Pending CN112879273A (en) | 2021-01-05 | 2021-01-05 | Implantable body fluid transport pump and pump system for directional transport of body fluid |
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| CN116025548A (en) * | 2022-12-30 | 2023-04-28 | 广东健齿生物科技有限公司 | Magnetic control flexible micropump and miniature motor |
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