CN112869827B

CN112869827B - Electrode device for generating seismic waves and using method

Info

Publication number: CN112869827B
Application number: CN202110013206.8A
Authority: CN
Inventors: 卜林鹏; 苗涛; 程增兵; 张大未; 林林
Original assignee: Suzhou Zhonghui Medical Technology Co ltd
Current assignee: Suzhou Zhonghui Medical Technology Co ltd
Priority date: 2021-01-06
Filing date: 2021-01-06
Publication date: 2022-09-20
Anticipated expiration: 2041-01-06
Also published as: CN112869827A

Abstract

The invention relates to an electrode device for generating seismic waves and a using method, wherein the electrode device is used for a cardiovascular stenosis lesion recanalization system; the electrode device comprises an electrode pair, a connecting lead and a guide pipe, the electrode device is arranged on the guide pipe, the electrode pair is coaxially and axially arranged, and the electrode pair comprises an electrode tip and a lead; the device can be matched with a generator of a balloon catheter control recanalization system to apply vibration waves to vibrate and dilate the narrow blood vessel attached to the periphery of the balloon to a certain recanalization rate, and the action direction and effect after the vibration waves are generated are controlled, so that the purpose of keeping the long-term normal blood vessel is achieved, and finally cardiovascular stenosis is treated; the invention has simple structure, lower cost and easy storage.

Description

Electrode device for generating seismic waves and using method

Technical Field

The invention belongs to the technical field of medical equipment, and particularly relates to an electrode device for generating seismic waves and a using method thereof.

Background

The blood vessel stenosis refers to the condition that lipid in blood is deposited on an original smooth blood vessel intima due to abnormal lipid metabolism of human artery and vein blood vessels, wrapped coronary vessels, peripheries, intracranial blood vessels and the like, lipid plaques of atheroma are gradually accumulated, and the plaques are increased or even calcified to cause the stenosis in the blood vessel cavity along with the lapse of time, so that the blood flow is blocked, the blood vessels and the human body at the downstream are ischemic, and the corresponding clinical manifestations are generated. If the stenosis occurs in coronary artery, palpitation, chest pain, dyspnea and angina can be caused, and serious patients can cause insufficient blood supply to cardiac muscle or cardiac muscle necrosis; if it occurs peripherally, there is a decrease in skin epidermal temperature, muscle atrophy, intermittent claudication and even necrosis or amputation of the distal limb. If it occurs in the cranium, dizziness, syncope, and even brain tissue damage and brain dysfunction can occur.

With the development of cardiovascular intervention technology, the technology aiming at angiostenosis lesion is gradually diversified; for the lesion with higher stenosis degree and serious calcification, the existing technology is to firstly pass through a lesion blood vessel by a guide wire, then place a high-pressure balloon at the stenosis position for pre-expansion, and finally implant a vascular stent at the target stenosis position by exchanging a stent delivery system. The technology also has many problems at present, 10-15 atmospheres are sometimes needed for pre-expanding the blood vessel for the pathological changes with serious calcification, and 30 atmospheres are sometimes needed, and the result brought by the high pressure inevitably causes the calcified plaque to transfer stress to the inner wall of the blood vessel to cause blood vessel damage, and serious patients cause blood vessel interlayer or perforation. In addition, clinical studies have shown that the long-term restenosis rate of the lesions after the stent has been successfully implanted is high, because the stent is a foreign substance, and the continuous stimulation of the vascular intima can cause intimal hyperplasia, and further restenosis of the blood vessel occurs.

Chinese patent CN111568500A discloses a blood vessel recanalization system for cardiovascular stenosis, which comprises a balloon, an energy generation controller, and a catheter, wherein the catheter comprises a main body tube, one end of the catheter is connected with the energy generation controller, the main body tube at the other end of the catheter is connected with one end of the balloon, the balloon comprises a balloon main body, an inner tube, and an electrode pair, the energy generation controller can send and regulate a vibration signal with specific frequency to vibrate the electrode pair, so as to solve the problem of blood vessel injury caused by simple high-pressure balloon pre-expansion in the existing cardiovascular intervention technology, and the invention has a drug loading function, and the drug can inhibit the increase of the recanalization membrane of the recanalization blood vessel, thereby avoiding the occurrence of restenosis after recanalization. However, the electrode pair used in the invention has a single design, and the action direction and effect after the shock wave occurs cannot be controlled, so that the effect of the system on the pathological change treatment is weakened.

In view of the above, a problem to be solved by those skilled in the art is how to overcome the limitations of the prior art, and to control the action direction and effect of the system after the occurrence of the seismic wave through the design change of the electrode device, so that the system has a better effect on the treatment of the pathological changes.

Disclosure of Invention

In view of this, the present application aims to provide an electrode device for generating a seismic wave, which can control the action direction and the action effect of the seismic wave in the use process of a system, and can quickly and accurately diagnose a lesion position so as to achieve the purposes of keeping the long-term patency of a blood vessel and treating stenosis of the blood vessel.

In order to achieve the above object, the present application provides the following technical solutions.

An electrode device for generating seismic waves for use in a cardiovascular stenosis recanalization system; the electrode device comprises an electrode pair, a connecting lead and a catheter, and is arranged on the catheter in a coaxial and axial arrangement mode; the electrode pair comprises an electrode tip and a lead, a power supply device is connected to the electrode device to form a loop, and the electrode device is connected with the power supply device through the lead.

Preferably, the number of the electrode tips is n, which is a natural number greater than 1.

Preferably, the connection mode among the n electrode tips is one or any combination of the connection of single electrode tips through a lead wire or the connection of a plurality of electrode tips after the combination connection.

Preferably, the material of the electrode head is a conductive material, including: one or a combination of metal, graphite and carbon fiber.

Preferably, a gap exists between the electrode tips, and the width of the gap is 0.05-2 mm.

Preferably, the gaps are distributed on the peripheral surface of the guide pipe in the direction of 0-180 degrees.

Preferably, the connection mode of the electrode head and the lead wire comprises one or a combination of welding, gluing, crimping and extruding.

Preferably, the solder joint solder, the adhesive filler comprises one or a combination of tin, silver.

Preferably, the conduit is a cylindrical tube or a profiled tube with an axial profile with a certain number of slots.

A method of using an electrode device for generating seismic waves, the steps comprising:

s1, connecting the electrode tip with the lead;

s2, the power supply device forms a loop with the electrode device through the lead wire and supplies power to the electrode device;

s3, when the electrode device is immersed in the conducting fluid and the power supply device starts to discharge in sequence, the electrode device will generate a controlled shock wave at the gap.

The invention has the following beneficial technical effects:

1) the invention has simple structure, small volume and convenient reception, and realizes the diagnosis and treatment operation of the recanalization seismic wave of the blood vessel.

2) The invention can be matched with a balloon catheter to carry out a conventional interventional operation mode, and a generator of a control recanalization system applies vibration waves to vibrate and expand a narrow blood vessel attached to the periphery of the balloon to a certain recanalization rate, so that the aim of keeping the long-term normal blood vessel is fulfilled, and the aim of treating cardiovascular stenosis is finally fulfilled.

3) The invention controls the action direction and effect after the shock wave occurs through the design transformation of the related electrode device, so that the system has better effect on the lesion treatment.

The foregoing description is only an overview of the technical solutions of the present application, so that the technical means of the present application can be more clearly understood and the present application can be implemented according to the content of the description, and in order to make the above and other objects, features and advantages of the present application more clearly understood, the following detailed description is made with reference to the preferred embodiments of the present application and the accompanying drawings.

The above and other objects, advantages and features of the present application will become more apparent to those skilled in the art from the following detailed description of specific embodiments thereof, taken in conjunction with the accompanying drawings.

Drawings

In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the drawings needed to be used in the description of the embodiments or the prior art will be briefly introduced below, and it is obvious that the drawings in the following description are some embodiments of the present application, and it is obvious for those skilled in the art to obtain other drawings based on these drawings without creative efforts. Throughout the drawings, like elements or portions are generally identified by like reference numerals. In the drawings, elements or portions are not necessarily drawn to scale.

FIG. 1 is a two-dimensional expanded view of electrode pairs arranged coaxially and axially;

FIG. 2 is a three-directional expanded view of electrode pairs arranged in a coaxial axial arrangement;

fig. 3 is a four-way development of the electrode pairs arranged coaxially and axially.

Detailed Description

In order to make the objects, technical solutions and advantages of the embodiments of the present application clearer, the technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application, and it is obvious that the described embodiments are some embodiments of the present application, but not all embodiments. In the following description, specific details such as specific configurations and components are provided only to facilitate a thorough understanding of embodiments of the present application. Accordingly, it will be apparent to those skilled in the art that various changes and modifications may be made to the embodiments described herein without departing from the scope and spirit of the present application. In addition, descriptions of well-known functions and constructions are omitted in the embodiments for clarity and conciseness.

It should be appreciated that reference throughout this specification to "one embodiment" or "the embodiment" means that a particular feature, structure or characteristic described in connection with the embodiment is included in at least one embodiment of the present application. Thus, the appearances of the phrase "one embodiment" or "the present embodiment" in various places throughout this specification are not necessarily all referring to the same embodiment. Furthermore, the particular features, structures, or characteristics may be combined in any suitable manner in one or more embodiments.

Further, the present application may repeat reference numerals and/or letters in the various examples. This repetition is for the purpose of simplicity and clarity and does not in itself dictate a relationship between the various embodiments and/or configurations discussed.

The term "and/or" herein is merely an association describing an associated object, meaning that three relationships may exist, e.g., a and/or B, may mean: a exists alone, B exists alone, and A and B exist at the same time, and the term "/and" is used herein to describe another association object relationship, which means that two relationships may exist, for example, A/and B, may mean: a alone, and both a and B alone, and further, the character "/" in this document generally means that the former and latter associated objects are in an "or" relationship.

The term "at least one" herein is merely an association relationship describing an associated object, and means that there may be three relationships, for example, at least one of a and B, may mean: a exists alone, A and B exist simultaneously, and B exists alone.

It is further noted that, herein, relational terms such as first and second, and the like may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion.

Example 1

An electrode device for generating seismic waves for use in a cardiovascular stenosis lesion recanalization system; the electrode device comprises an electrode pair, a connecting lead and a catheter, and is arranged on the catheter in a coaxial and axial arrangement mode; the electrode pair comprises an electrode tip and a lead, a power supply device is connected to the electrode device to form a loop, and the electrode device is connected with the power supply device through the lead.

Further, the number of the electrode tips is n, and n is a natural number greater than 1.

Furthermore, the connection mode among the n electrode tips is one or any combination of the single electrode tips connected through a lead or the multiple electrode tips connected in combination first and then connected through a lead.

Further, the material of the electrode head is a conductive material, and the electrode head comprises: one or a combination of metal, graphite and carbon fiber.

Furthermore, a gap exists between the electrode tips, and the width of the gap is 0.05-2 mm.

Furthermore, the gaps are distributed on the peripheral surface of the conduit in the direction of 0-180 degrees.

Further, the connection mode of the electrode tip and the lead wire comprises one or a combination of welding, gluing, crimping and extruding.

Further, the solder joint solder, the adhesive filler comprises one of tin, silver or a combination thereof.

Further, the conduit is a cylindrical tube or a profiled tube with an axial profile with a number of slots.

s1, connecting the electrode tip with the lead;

s2, the power supply device forms a loop with the electrode device through the lead and supplies power to the electrode device;

Example 2

This embodiment is performed based on embodiment 1, and the same parts as those in the above embodiment are not repeated.

The conductive fluid is prepared by mixing a medical contrast agent and physiological saline according to a certain proportion. The voltage of the power supply device can be between 500 and 10000 volts, and the time for applying the voltage can be between 0.1 and 100 microseconds.

Further, the electrode tip material of the electrode device is one or any combination of stainless steel, tungsten alloy, nickel alloy, iron-platinum-iridium alloy, graphite and carbon fiber;

further, the material of the insulating interlayer can be selected from one or any combination of polyimide, ceramic and polytetrafluoroethylene.

Furthermore, the conducting wire can be selected from enameled copper wires and other conducting wires with relatively good conductivity.

Further, the lead can be selectively connected with the electrode head so as to supply power to the electrode device.

Further, the electrode devices are each fixed to the catheter by an adhesive (ultraviolet curing glue or the like), crimping, welding, extrusion, or the like.

Example 3

This embodiment is explained based on the above embodiment 1, and the same parts as those of the above embodiment 1 are not repeated.

This embodiment mainly describes a two-direction electrode device arranged coaxially and axially.

As shown in fig. 1, the electrode device, which includes an electrode tip 1, an electrode tip 2a, an electrode tip 2b, a wire 3a and a wire 3b, is mounted on a guide tube 5. Wherein the electrode head 1 is not in contact with the electrode heads 2 and 3, respectively, with

gaps

4a and 4b between them.

Further, the gap 4a and the gap 4b are equal and are both 1 mm.

Further, the electrode tip 1 is an integrated electrode tip or two electrode tips are connected into a whole through a lead.

Further, the electrode tip 2a is connected to the lead wire 3a, and the electrode tip 2b is connected to the lead wire 3 b.

Further, the

gaps

4a and 4b are respectively disposed at both sides of the guide duct 5 at 180 ° directions.

The use method of the electrode device comprises the following steps: the power supply device forms a loop with the electrode device through

leads

3a and 3b and supplies power to the electrode device; when the electrode assembly is immersed in the conductive fluid and the power supply begins to discharge in a programmed sequence, the electrode assembly will generate controlled seismic waves in the

gaps

4a and 4b, thereby achieving therapeutic purposes.

Example 4

This embodiment mainly introduces a three-directional electrode device arranged coaxially and axially.

As shown in fig. 2, the electrode device includes an electrode tip 1a, an electrode tip 1b, an electrode tip 1c, an electrode tip 2a, an electrode tip 2b, an electrode tip 2c, a wire 3, and a wire 4; wherein the electrode tip 1a, the electrode tip 1b, the electrode tip 1c and the electrode tip 2a, the electrode tip 2b, the electrode tip 2c are not in contact with each other, respectively, and maintain a certain gap.

Further, the gaps are equal and are all 2 mm.

Further, the electrode taps 1a and 1b are integrated or separate electrode taps are connected by a wire.

Further, the electrode taps 2b and 2c are integrated or separate electrode taps are connected by a wire.

Further, three gaps are distributed on the outer peripheral surface of the guide pipe 5 and are respectively in the 120-degree direction, and the two gaps can enable the electrode device to uniformly generate shock waves in three directions around the circumference.

The use method of the device comprises the following steps: when the electrode device is immersed in the conductive fluid and the power supply device starts to discharge orderly according to the program, the electrode device can generate controllable shock waves at the three gaps, thereby achieving the purpose of treatment.

Example 5

This embodiment mainly describes a four-direction electrode device arranged coaxially and axially.

As shown in fig. 3, an electrode tip 1a, an electrode tip 1b, an electrode tip 1c, an electrode tip 1d, an electrode tip 2a, an electrode tip 2b, an electrode tip 2c, an electrode tip 2d, a wire 3, and a wire 4. Wherein the electrode tips 1a to 1d and the electrode tips 2a to 2d do not contact each other, respectively, and maintain a certain gap. The electrode taps 1a and 1b, the electrode taps 2b and 2c, and the electrode taps 1c and 1d may be one electrode tap as one body or two electrode taps connected together by a wire.

Further, four gaps are distributed on the outer peripheral surface of the guide tube 5 and are respectively arranged in a 90-degree direction, so that the electrode device can uniformly generate shock waves in four mutually perpendicular directions around the circumference.

The number of the combination of the shock wave generating openings can be continuously changed into 5, 6 or even more, and the structure of the catheter and the structure of the electrode are correspondingly changed according to the actual situation while the number is changed.

The above description is only a preferred embodiment of the present invention, and it is not intended to limit the scope of the present invention, and various modifications and changes may be made by those skilled in the art. Variations, modifications, substitutions, integrations and parameter changes of the embodiments may be made without departing from the principle and spirit of the invention, which may be within the spirit and principle of the invention, by conventional substitution or may realize the same function.

Claims

1. An electrode device for generating seismic waves, wherein the electrode device is used in a cardiovascular stenosis lesion recanalization system; the electrode device comprises an electrode pair, a connecting lead and a catheter,

the electrode pair consists of an electrode tip and a lead, the electrode pair and the lead are arranged on the catheter, and the electrode pair is coaxially and axially arranged;

the electrode device is connected with a power supply device to form a loop, and the electrode device is connected with the power supply device through a lead;

the number of the electrode tips is n, and n is a natural number more than 1; the connection mode among the n electrode tips is one or any combination of the single electrode tips connected through a lead or the multiple electrode tips combined and connected first and then connected through the lead; gaps are formed among the electrode tips, and the width of each gap is 0.05-2 mm; the gaps are distributed on the peripheral surface of the conduit and form a direction of 0-180 degrees;

the material of electrode head is conducting material, includes: one or a combination of metal, graphite and carbon fiber.

2. An electrode device for generating seismic waves according to claim 1, wherein the connection of the electrode head to the lead wire comprises one or a combination of welding, gluing, crimping, and pressing.

3. An electrode device for generating seismic waves according to claim 2, wherein the solder joints are soldered with solder, an adhesive filler comprising one of tin, silver or a combination thereof.

4. An electrode device for generating seismic waves according to claim 1, wherein said conduit is a cylindrical tube or a profiled tube having an axial profile with a number of slots.