CN112857709A - Method and device for detecting medicine package tightness - Google Patents

Method and device for detecting medicine package tightness Download PDF

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Publication number
CN112857709A
CN112857709A CN202110051501.2A CN202110051501A CN112857709A CN 112857709 A CN112857709 A CN 112857709A CN 202110051501 A CN202110051501 A CN 202110051501A CN 112857709 A CN112857709 A CN 112857709A
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information
medicine
obtaining
air pressure
detection
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王洪军
马胜楠
超光超
蒲丽萍
栾美丽
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Beijing Pharmaceutical Race And Co ltd
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Beijing Pharmaceutical Race And Co ltd
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Priority to CN202110051501.2A priority Critical patent/CN112857709A/en
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01MTESTING STATIC OR DYNAMIC BALANCE OF MACHINES OR STRUCTURES; TESTING OF STRUCTURES OR APPARATUS, NOT OTHERWISE PROVIDED FOR
    • G01M3/00Investigating fluid-tightness of structures
    • G01M3/02Investigating fluid-tightness of structures by using fluid or vacuum
    • G01M3/26Investigating fluid-tightness of structures by using fluid or vacuum by measuring rate of loss or gain of fluid, e.g. by pressure-responsive devices, by flow detectors
    • G01M3/32Investigating fluid-tightness of structures by using fluid or vacuum by measuring rate of loss or gain of fluid, e.g. by pressure-responsive devices, by flow detectors for containers, e.g. radiators
    • G01M3/3236Investigating fluid-tightness of structures by using fluid or vacuum by measuring rate of loss or gain of fluid, e.g. by pressure-responsive devices, by flow detectors for containers, e.g. radiators by monitoring the interior space of the containers
    • G01M3/3263Investigating fluid-tightness of structures by using fluid or vacuum by measuring rate of loss or gain of fluid, e.g. by pressure-responsive devices, by flow detectors for containers, e.g. radiators by monitoring the interior space of the containers using a differential pressure detector

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  • General Physics & Mathematics (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Abstract

The invention discloses a method and a device for detecting the sealing performance of a medicine package, wherein the method comprises the following steps: obtaining first environmental air pressure information according to first production region information of the first medicine; obtaining first use region information of the first medicine; acquiring second environmental air pressure information according to the first using region information of the first medicine; acquiring first air pressure difference information according to the first environmental air pressure information and the second environmental air pressure information; inputting the medicine category information and the first air pressure difference information into a tightness detection model to obtain a first detection standard of the tightness of the first medicine; and judging whether the sealing performance information meets the first detection standard or not, and obtaining a first detection result. The technical problems that in the prior art, the medicine storage is not accurately influenced by the sealing detection, and the body health of a patient is harmed are solved.

Description

Method and device for detecting medicine package tightness
Technical Field
The invention relates to the field of package sealing, in particular to a method and a device for detecting the sealing performance of medicine packages.
Background
In order to better ensure the safety of medicine packaging, a medicine packaging enterprise needs to carefully cut off the packaging design and strictly control the production process, wherein the detection of medicine packaging is one of the key links, and in order to better guarantee the medicine quality, the medicine packaging enterprise needs to detect the tightness of medicine packaging.
However, in the process of implementing the technical solution of the invention in the embodiments of the present application, the inventors of the present application find that the above-mentioned technology has at least the following technical problems:
the technical problems that the medicine storage is influenced and the body health of a patient is harmed due to inaccurate tightness detection in the prior art exist.
Disclosure of Invention
The embodiment of the application provides a method and a device for detecting the sealing property of a medicine package, solves the technical problems that in the prior art, the sealing property detection does not accurately influence medicine storage and harm the body health of a patient, achieves the technical effects of improving the accuracy and the feasibility of the detection of the sealing property of the medicine package and providing guiding basis for the production quality of a pharmaceutical factory.
In view of the above problems, embodiments of the present application provide a method and an apparatus for detecting the sealability of a medicine package.
In a first aspect, the present embodiments provide a method for detecting the sealability of a pharmaceutical product package, the method including: obtaining drug category information for a first drug; obtaining first production location information for the first drug; obtaining first environmental air pressure information according to first production region information of the first medicine; obtaining first use region information of the first medicine; acquiring second environmental air pressure information according to the first using region information of the first medicine; acquiring first air pressure difference information according to the first environmental air pressure information and the second environmental air pressure information; inputting the medicine category information and the first air pressure difference information into a tightness detection model to obtain a first detection standard of the tightness of the first medicine; obtaining sealability information of a first drug; and judging whether the sealing performance information meets the first detection standard or not, and obtaining a first detection result.
In another aspect, the present application further provides a device for detecting the sealability of a pharmaceutical package, the device comprising: a first obtaining unit for obtaining medicine category information of a first medicine; a second obtaining unit for obtaining first production location information of the first medicine; a third obtaining unit configured to obtain first ambient air pressure information based on first production location information of the first medicine; a fourth obtaining unit, configured to obtain first usage region information of the first medicine; a fifth obtaining unit, configured to obtain second ambient air pressure information according to the first usage region information of the first medicine; a sixth obtaining unit, configured to obtain first air pressure difference information according to the first environmental air pressure information and the second environmental air pressure information; a seventh obtaining unit, configured to input the medicine category information and the first air pressure difference information into a sealing performance detection model, and obtain a first detection criterion of sealing performance of the first medicine; an eighth obtaining unit configured to obtain sealing information of the first medicine; a ninth obtaining unit, configured to determine whether the sealing information meets the first detection criterion, and obtain a first detection result.
In a third aspect, the present invention provides an apparatus for testing the sealability of pharmaceutical packages, comprising a memory, a processor and a computer program stored on the memory and executable on the processor, wherein the processor executes the program to perform the steps of the method of the first aspect.
One or more technical solutions provided in the embodiments of the present application have at least the following technical effects or advantages:
the method comprises the steps of obtaining medicine category information of a first medicine, obtaining first production region information of the first medicine, obtaining first environmental air pressure information according to the first production region information of the first medicine, obtaining first use region information of the first medicine, obtaining second environmental air pressure information according to the first use region information of the first medicine, obtaining first air pressure difference information according to the first environmental air pressure information and the second environmental air pressure information, inputting the medicine category information and the first air pressure difference information into a tightness detection model, obtaining a first detection standard of tightness of the first medicine, obtaining tightness information of the first medicine, judging whether the tightness information meets the first detection standard or not, and obtaining a first detection result. Thereby achieving the technical effects of improving the accuracy and the feasibility of the detection of the sealing performance of the medicine package and providing an instructive basis for the production quality of pharmaceutical factories.
The foregoing description is only an overview of the technical solutions of the present application, and the present application can be implemented according to the content of the description in order to make the technical means of the present application more clearly understood, and the following detailed description of the present application is given in order to make the above and other objects, features, and advantages of the present application more clearly understandable.
Drawings
FIG. 1 is a schematic flow chart illustrating a method for testing the sealing performance of a pharmaceutical package according to an embodiment of the present application;
FIG. 2 is a schematic structural diagram of an apparatus for testing the sealing performance of a pharmaceutical package according to an embodiment of the present application;
fig. 3 is a schematic structural diagram of an exemplary electronic device according to an embodiment of the present application.
Description of reference numerals: a first obtaining unit 11, a second obtaining unit 12, a third obtaining unit 13, a fourth obtaining unit 14, a fifth obtaining unit 15, a sixth obtaining unit 16, a seventh obtaining unit 17, an eighth obtaining unit 18, a ninth obtaining unit 19, a bus 300, a receiver 301, a processor 302, a transmitter 303, a memory 304, a bus interface 306.
Detailed Description
The embodiment of the application provides a method and a device for detecting the sealing property of a medicine package, solves the technical problems that in the prior art, the sealing property detection does not accurately influence medicine storage and harm the body health of a patient, achieves the technical effects of improving the accuracy and the feasibility of the detection of the sealing property of the medicine package and providing guiding basis for the production quality of a pharmaceutical factory. Hereinafter, example embodiments according to the present application will be described in detail with reference to the accompanying drawings. It should be apparent that the described embodiments are merely some embodiments of the present application and not all embodiments of the present application, and it should be understood that the present application is not limited to the example embodiments described herein.
Summary of the application
In order to better ensure the safety of medicine packaging, a medicine packaging enterprise needs to carefully cut off the packaging design and strictly control the production process, wherein the detection of medicine packaging is one of the key links, and in order to better guarantee the medicine quality, the medicine packaging enterprise needs to detect the tightness of medicine packaging. But the prior art has the technical problems that the medicine storage is influenced and the body health of a patient is harmed because the tightness detection is inaccurate.
In view of the above technical problems, the technical solution provided by the present application has the following general idea:
the embodiment of the application provides a method for detecting the tightness of a medicine package, which comprises the following steps: obtaining drug category information for a first drug; obtaining first production location information for the first drug; obtaining first environmental air pressure information according to first production region information of the first medicine; obtaining first use region information of the first medicine; acquiring second environmental air pressure information according to the first using region information of the first medicine; acquiring first air pressure difference information according to the first environmental air pressure information and the second environmental air pressure information; inputting the medicine category information and the first air pressure difference information into a tightness detection model to obtain a first detection standard of the tightness of the first medicine; obtaining sealability information of a first drug; and judging whether the sealing performance information meets the first detection standard or not, and obtaining a first detection result.
Having thus described the general principles of the present application, various non-limiting embodiments thereof will now be described in detail with reference to the accompanying drawings.
Example one
As shown in fig. 1, an embodiment of the present application provides a method for detecting the sealability of a pharmaceutical product package, wherein the method includes:
step S100: obtaining drug category information for a first drug;
specifically, the first medicine is a target object for detecting the sealing performance of the package, and the medicine type information of the first medicine is related information for classifying the medicine into a prescription medicine and an over-the-counter medicine according to the safety and effectiveness principle of the medicine and according to the difference of the variety, the specification, the indication, the dosage, the administration route and the like, and making corresponding management regulations.
Step S200: obtaining first production location information for the first drug;
specifically, the first production region information of the first medicine is production system information with certain regional characteristics for producing the first medicine, and is an expression form of labor regional division, and different types of production regions have different development conditions, development levels, economic structures and production combination characteristics.
Step S300: obtaining first environmental air pressure information according to first production region information of the first medicine;
specifically, the first ambient air pressure information is an atmospheric pressure acting on a unit area of the first production area of the first medicine, that is, a gravity force applied to a vertical air column extending upward to an upper air boundary in a unit area, and the ambient air pressure varies depending on not only the altitude but also the temperature, and the variation of the ambient air pressure is closely related to the weather variation.
Step S400: obtaining first use region information of the first medicine;
step S500: acquiring second environmental air pressure information according to the first using region information of the first medicine;
specifically, the first usage region information of the first medicine is usage system information having a certain regional characteristic for using the first medicine, the second environmental air pressure information is atmospheric pressure acting on a unit area of a first usage region of the first medicine, and the second environmental air pressure information is obtained according to the first usage region information of the first medicine, wherein the second environmental air pressure information may be the same as or different from the first environmental air pressure information, for example, the first medicine is produced in Shijiazhuan and transports the first medicine to various places with different air pressures, such as Tibet, inner Mongolia, Guangzhou, Shanghai, and the like.
Step S600: acquiring first air pressure difference information according to the first environmental air pressure information and the second environmental air pressure information;
specifically, the first air pressure difference information is air pressure value information of a phase difference obtained according to the pressure of the first ambient air pressure space gas and the pressure of the adjacent second ambient air pressure space gas, so that the technical effect of providing an instructive basis for the production quality of the medicine through the air pressure difference between the production region and the use region is achieved.
Step S700: inputting the medicine category information and the first air pressure difference information into a tightness detection model to obtain a first detection standard of the tightness of the first medicine;
further, in a step S700 of this embodiment of the present application, the inputting the medicine category information and the first air pressure difference information into a tightness detection model to obtain a first detection criterion of the tightness of the first medicine, further includes:
step S710: inputting the medicine category information and the first air pressure difference information into a tightness detection model, wherein the tightness detection model is obtained by training a plurality of groups of training data, and each group of the plurality of groups of training data comprises: the drug category information, the first air pressure difference information and identification information identifying a first detection standard;
step S720: and obtaining a first output result of the tightness detection model, wherein the first output result comprises a first detection standard of the tightness of the first medicine.
Specifically, the tightness detection model is a Neural network model, i.e., a Neural network model in machine learning, and a Neural Network (NN) is a complex Neural network system formed by widely interconnecting a large number of simple processing units (called neurons), which reflects many basic features of human brain functions, and is a highly complex nonlinear dynamical learning system. Neural network models are described based on mathematical models of neurons. Artificial Neural Networks (ANN), is a description of the first-order properties of the human brain system. Briefly, it is a mathematical model. And inputting the medicine category information and the first air pressure difference information into a neural network model through training of a large amount of training data, and outputting a first detection standard of the first medicine tightness.
More specifically, the training process is essentially a supervised learning process, each group of supervised data includes the medicine category information, the first air pressure difference information and identification information for identifying a first detection standard, the medicine category information and the first air pressure difference information are input into a neural network model, the neural network model performs continuous self-correction and adjustment according to the identification information for identifying the first detection standard, and the present group of supervised learning is ended and the next group of data supervised learning is performed until the obtained first output result is consistent with the identification information; and when the output information of the neural network model reaches the preset accuracy rate/reaches the convergence state, finishing the supervised learning process. Through the supervision and learning of the neural network model, the neural network model can process the input information more accurately, the first detection standard of the sealing performance of the output first medicine is more reasonable and accurate, and the technical effects of ensuring the sealing performance of medicine packaging and providing guiding basis for the production quality of a pharmaceutical factory are achieved.
Step S800: obtaining sealability information of a first drug;
step S900: and judging whether the sealing performance information meets the first detection standard or not, and obtaining a first detection result.
Specifically, the sealing information of the first medicine is information for detecting the sealing of the first medicine package and detecting whether the first medicine package leaks, the first detection result is information for judging whether the sealing information of the first medicine obtained by detection meets the first detection standard output by the sealing detection model, and the technical effect of ensuring the sealing performance of the medicine package is further achieved
Further, in step S800 of obtaining the information about the sealability of the first medicine, the method further includes:
step S810: obtaining sealing material information of the first drug;
step S820: obtaining the information of the internal and external pressure difference of the first medicine package;
step S830: and inputting the sealing material information of the first medicine and the internal and external pressure difference information of the first medicine package into a sealing detection model to obtain the sealing information of the first medicine.
Specifically, the sealing material information of the first chemical is a packaging sealing material of the first chemical, the sealing material is classified into a fixed type sealing material and an unfixed type sealing material, and the sealing material has different requirements for mechanical properties such as strength, deformation rate, and elasticity depending on the type of the first chemical. The internal and external pressure difference information of the first medicine package is that the first medicine package is subjected to two pressures from inside to outside and from outside to inside, the difference between the two pressures is just the internal and external pressure difference information, the sealing material information of the first medicine and the internal and external pressure difference information of the first medicine package are input into the sealing detection model, the sealing detection model is a neural network model, and the neural network model is supervised and learned through the neural network model, so that the neural network model processes the input information is more accurate, further the sealing information of the output first medicine is more reasonable and accurate, further the accuracy and the feasibility of the detection of the sealing performance of the medicine package are improved, and the technical effect of providing guiding basis for the production quality of a pharmaceutical factory is achieved.
Further, step S830 in this embodiment of the present application further includes:
step S831: obtaining a predetermined moisture resistance coefficient threshold;
step S832: obtaining a moisture resistance coefficient of a sealing material of the first pharmaceutical product;
step S833: judging whether the moisture-proof coefficient is within the preset moisture-proof coefficient threshold value or not to obtain a first weighted score;
step S834: and obtaining a second detection result according to the first weighted score and the first detection result.
Specifically, the predetermined moisture-proof coefficient threshold value is a critical value required by a moisture-proof packaging grade coefficient of the product package specified in the product technical document when the first medicine needs to be moisture-proof packaged, and is a lowest value or a highest value of the predetermined moisture-proof coefficient, and the moisture-proof coefficient of the sealing material of the first medicine is a moisture-proof grade coefficient of the sealing material packaged according to general performance factors such as the property, the circulation environment, the storage and transportation time, the packaging container and the like of the first medicine. The first weighted score is a weighted average, and is the score of data with different specific gravities obtained by judging whether the moisture-proof coefficient is within the preset moisture-proof coefficient threshold value, the weighted score is calculated by reasonably proportioning the original data, and the second detection result is the detection result obtained by integrating the moisture-proof performance of the sealing material of the first medicine according to the first weighted score and the first detection result, namely the air pressure difference tightness detection result.
Further, wherein, the determining whether the moisture protection factor is within the predetermined moisture protection factor threshold value to obtain a first weighted score, step S833 of this embodiment of the present application further includes:
step S8331: obtaining a first negative weighted score if the moisture resistance factor is not within the predetermined moisture resistance factor threshold;
step S8332: obtaining a first positive weighted score if the moisture barrier coefficient is within the predetermined moisture barrier coefficient threshold.
Specifically, if the moisture resistance coefficient of the sealing material of the first medicine is not within the predetermined moisture resistance coefficient threshold value, the first weighted score specific gravity is a negative number, and if the moisture resistance coefficient of the sealing material of the first medicine is within the predetermined moisture resistance coefficient threshold value, the first weighted score specific gravity is a positive number, so that the technical effect of ensuring the sealing performance of the medicine package by detecting the moisture resistance performance of the sealing material of the medicine is achieved.
Further, in step S831 of the embodiment of the present application, wherein the obtaining of the predetermined moisture resistance coefficient threshold further includes:
step S8311: obtaining first humidity information of the first production region;
step S9312: obtaining second humidity information of the first use region;
step S8313: comparing the first humidity information with the second humidity information, and taking the maximum value to obtain third humidity information;
step S8314: and obtaining a preset moisture-proof coefficient threshold value according to the third humidity information.
Specifically, the first humidity information of the first production area is physical quantity information indicating the degree of dryness of the atmosphere in the first production area, and the air is drier as the moisture contained in a certain volume of air at a certain temperature is smaller, and the air is more humid as the moisture is larger, and the degree of dryness of the air is called "humidity". And the second humidity information of the first use region is physical quantity information representing the atmospheric dryness degree of the first use region, the third humidity information is the larger humidity information of the first humidity information and the second humidity information, and the preset moisture-proof coefficient threshold value is obtained according to the third humidity information.
Further, the embodiment of the present application further includes:
step S1010: obtaining component information of the first drug;
step S1020: judging whether the component information has photochemical reaction characteristics or not according to the component information of the first medicine;
step S1030: if the component information has the photochemical reaction characteristic, obtaining the light-shielding grade of the sealing material of the first medicine;
step S1040: obtaining a second weighted score according to the light-shielding grade of the first medicine sealing material;
step S1050: and obtaining a third detection result according to the second weighted score and the first detection result.
Specifically, the ingredient information of the first drug is any one substance or a mixture of substances used in the manufacture of the first drug, which has pharmacological activity or other direct effects or information that can affect the function or structure of the body in the diagnosis, treatment, symptom relief, treatment, or prevention of a disease. And judging whether the component information has the characteristic of photochemical reaction or not according to the component information of the first medicine, wherein the photochemical reaction is also called photochemical action and refers to chemical reaction caused by the action of light, namely chemical reaction generated by the matter absorbing light energy under the irradiation of visible light or ultraviolet light, so that the first medicine component is subjected to photochemical reaction and decomposed to generate gas, and the sealing property of the medicine package is further influenced. The light-shielding grade of the sealing material of the first medicine is that if the component information has photochemical reaction characteristics, the light-shielding grade of the packaging material of the product on light, oxygen and water vapor permeation, namely the light-shielding property of the packaging material, and can be classified into whole light-shielding storage and light-shielding infusion. The second weighted score is a weighted average and is a score of data with different specific gravities obtained according to the light shielding grade of the first medicine sealing material, and the third detection result is a detection result obtained by integrating the light shielding performance of the sealing material of the first medicine according to the second weighted score and the first detection result, namely the air pressure difference sealing performance detection result, so that the accuracy and the feasibility of the medicine packaging sealing performance detection are improved, and an instructive basis can be provided for the production quality of a pharmaceutical factory.
Further, the step S710 of inputting the medicine category information and the first air pressure difference information into a neural network model further includes:
step S711: obtaining first training data, second training data and Nth training data which are input into the neural network model, wherein N is a natural number larger than 1;
step S712: generating first identification codes according to the first training data, wherein the first identification codes correspond to the first training data one by one;
step S713: generating a second identification code according to the second training data and the first identification code, and generating an Nth identification code according to the Nth training data and the (N-1) th identification code by analogy;
step S714: all training data and identification codes are copied and stored on M electronic devices, wherein M is a natural number greater than 1.
In particular, the blockchain technique, also referred to as a distributed ledger technique, is an emerging technique in which several computing devices participate in "accounting" together, and maintain a complete distributed database together. The blockchain technology has been widely used in many fields due to its characteristics of decentralization, transparency, participation of each computing device in database records, and rapid data synchronization between computing devices. Generating first identification codes according to the first training data, wherein the first identification codes correspond to the first training data one to one; generating a second identification code according to the second training data and the first identification code, wherein the second identification code corresponds to the second training data one to one; and by analogy, generating an Nth identification code according to the Nth training data and the (N-1) th identification code, wherein N is a natural number greater than 1, and each group in the training data comprises the medicine category information, the first air pressure difference information and identification information for identifying a first detection standard. Respectively copying and storing all training data and identification codes on M devices, wherein the first training data and the first identification code are stored on one device as a first block, the second training data and the second identification code are stored on one device as a second block, the Nth training data and the Nth identification code are stored on one device as an Nth block, when the training data are required to be called, after each subsequent node receives data stored by a previous node, the data are checked through a common identification mechanism and then stored, each storage unit is connected in series through a Hash function, so that the training data are not easy to lose and damage, the training data are encrypted through logic of a block chain, the safety of the training data is ensured, and the accuracy of a neural network model obtained through training the training data is further ensured, and then make the first detection standard of the first medicine leakproofness of output more reasonable, accurate, and then reach the technical effect who guarantees medicine packing sealing performance and can provide instructive foundation for the production quality of pharmaceutical factory.
In summary, the method and the device for detecting the sealing performance of the medicine package provided by the embodiment of the application have the following technical effects:
1. the method comprises the steps of obtaining medicine category information of a first medicine, obtaining first production region information of the first medicine, obtaining first environmental air pressure information according to the first production region information of the first medicine, obtaining first use region information of the first medicine, obtaining second environmental air pressure information according to the first use region information of the first medicine, obtaining first air pressure difference information according to the first environmental air pressure information and the second environmental air pressure information, inputting the medicine category information and the first air pressure difference information into a tightness detection model, obtaining a first detection standard of tightness of the first medicine, obtaining tightness information of the first medicine, judging whether the tightness information meets the first detection standard or not, and obtaining a first detection result. Thereby achieving the technical effects of improving the accuracy and the feasibility of the detection of the sealing performance of the medicine package and providing an instructive basis for the production quality of pharmaceutical factories.
2. The mode of inputting the medicine category information and the first air pressure difference information into the neural network model is adopted, so that the first detection standard of the output first medicine sealing performance is more reasonable and accurate, the technical effect of improving the accuracy of the medicine package sealing performance detection is achieved, the technical effect of providing guiding basis for the production quality of the medicine by detecting the air pressure difference between the production region and the use region is achieved, and the technical effect of ensuring the medicine package sealing performance by detecting the moisture resistance of the medicine sealing material is achieved.
Example two
Based on the same inventive concept as the method for detecting the tightness of the medicine package in the previous embodiment, the present invention further provides a device for detecting the tightness of the medicine package, as shown in fig. 2, the device comprises:
a first obtaining unit 11, wherein the first obtaining unit 11 is used for obtaining medicine category information of a first medicine;
a second obtaining unit 12, the second obtaining unit 12 being configured to obtain first production location information of the first medicine;
a third obtaining unit 13, where the third obtaining unit 13 is configured to obtain first ambient air pressure information according to first production region information of the first medicine;
a fourth obtaining unit 14, where the fourth obtaining unit 14 is configured to obtain first usage region information of the first medicine;
a fifth obtaining unit 15, where the fifth obtaining unit 15 is configured to obtain second environmental air pressure information according to the first usage region information of the first medicine;
a sixth obtaining unit 16, where the sixth obtaining unit 16 is configured to obtain first air pressure difference information according to the first environmental air pressure information and the second environmental air pressure information;
a seventh obtaining unit 17, where the seventh obtaining unit 17 is configured to input the medicine category information and the first air pressure difference information into a tightness detection model, and obtain a first detection criterion of tightness of the first medicine;
an eighth obtaining unit 18, wherein the eighth obtaining unit 18 is configured to obtain the sealing information of the first medicine;
a ninth obtaining unit 19, where the ninth obtaining unit 19 is configured to determine whether the sealing performance information meets the first detection criterion, and obtain a first detection result.
Further, the apparatus further comprises:
a first input unit, configured to input the medicine category information and the first air pressure difference information into a tightness detection model, where the tightness detection model is obtained by training multiple sets of training data, and each set of the multiple sets of training data includes: the drug category information, the first air pressure difference information and identification information identifying a first detection standard;
a tenth obtaining unit, configured to obtain a first output result of the sealing performance detection model, where the first output result includes a first detection criterion of the sealing performance of the first medicine.
Further, the apparatus further comprises:
an eleventh obtaining unit for obtaining sealing material information of the first medicine;
a twelfth obtaining unit for obtaining information on the difference between the internal pressure and the external pressure of the first medicine package;
a thirteenth obtaining unit configured to input the sealing material information of the first medicine and the internal-external pressure difference information of the first medicine package into a sealing detection model, and obtain the sealing information of the first medicine.
Further, the apparatus further comprises:
a fourteenth obtaining unit for obtaining a predetermined moisture resistance coefficient threshold value;
a fifteenth obtaining unit for obtaining a moisture resistance coefficient of a sealing material of the first medicine;
a sixteenth obtaining unit, configured to determine whether the moisture resistance coefficient is within the predetermined moisture resistance coefficient threshold value, and obtain a first weighted score;
a seventeenth obtaining unit, configured to obtain a second detection result according to the first weighted score and the first detection result.
Further, the apparatus further comprises:
an eighteenth obtaining unit for obtaining a first negative weighted score if the moisture resistance coefficient is not within the predetermined moisture resistance coefficient threshold;
a nineteenth obtaining unit for obtaining a first positive weighted score if the moisture barrier coefficient is within the predetermined moisture barrier coefficient threshold.
Further, the apparatus further comprises:
a twentieth obtaining unit for obtaining first humidity information of the first production zone;
a twenty-first obtaining unit, configured to obtain second humidity information of the first usage area;
a twenty-second obtaining unit, configured to compare the first humidity information with the second humidity information, obtain a maximum value, and obtain third humidity information;
a twenty-third obtaining unit, configured to obtain a predetermined moisture resistance coefficient threshold value according to the third humidity information.
Further, the apparatus further comprises:
a twenty-fourth obtaining unit for obtaining ingredient information of the first medicine;
a first determination unit configured to determine whether or not the component information has a photochemical reaction characteristic based on the component information of the first drug;
a twenty-fifth obtaining unit configured to obtain a light-shielding level of the sealing material of the first drug if the component information has a photochemical reaction characteristic;
a twenty-sixth obtaining unit, configured to obtain a second weighted score according to the light-shielding level of the first medicine sealing material;
a twenty-seventh obtaining unit, configured to obtain a third detection result according to the second weighted score and the first detection result.
Various modifications and embodiments of the method for detecting the sealability of the pharmaceutical package in the first embodiment of fig. 1 are also applicable to the apparatus for detecting the sealability of the pharmaceutical package in the present embodiment, and the method for detecting the sealability of the pharmaceutical package in the present embodiment will be apparent to those skilled in the art from the foregoing detailed description of the method for detecting the sealability of the pharmaceutical package, and therefore, for the sake of brevity of description, detailed description thereof will not be provided herein.
Exemplary electronic device
The electronic device of the embodiment of the present application is described below with reference to fig. 3.
Fig. 3 illustrates a schematic structural diagram of an electronic device according to an embodiment of the present application.
Based on the inventive concept of a method of detecting the sealability of a pharmaceutical package as described in the previous embodiments, the present invention further provides a device for detecting the sealability of a pharmaceutical package, on which a computer program is stored, which program, when being executed by a processor, performs the steps of any one of the methods of detecting the sealability of a pharmaceutical package as described in the previous embodiments.
Where in fig. 3 a bus architecture (represented by bus 300), bus 300 may include any number of interconnected buses and bridges, bus 300 linking together various circuits including one or more processors, represented by processor 302, and memory, represented by memory 304. The bus 300 may also link together various other circuits such as peripherals, voltage regulators, power management circuits, and the like, which are well known in the art, and therefore, will not be described any further herein. A bus interface 306 provides an interface between the bus 300 and the receiver 301 and transmitter 303. The receiver 301 and the transmitter 303 may be the same element, i.e., a transceiver, providing a means for communicating with various other systems over a transmission medium.
The processor 302 is responsible for managing the bus 300 and general processing, and the memory 304 may be used for storing data used by the processor 302 in performing operations.
The embodiment of the invention provides a method for detecting the sealing performance of a medicine package, which comprises the following steps: obtaining drug category information for a first drug; obtaining first production location information for the first drug; obtaining first environmental air pressure information according to first production region information of the first medicine; obtaining first use region information of the first medicine; acquiring second environmental air pressure information according to the first using region information of the first medicine; acquiring first air pressure difference information according to the first environmental air pressure information and the second environmental air pressure information; inputting the medicine category information and the first air pressure difference information into a tightness detection model to obtain a first detection standard of the tightness of the first medicine; obtaining sealability information of a first drug; and judging whether the sealing performance information meets the first detection standard or not, and obtaining a first detection result. The technical problems that in the prior art, the sealing performance detection is inaccurate, medicine storage is affected, and the health of a patient is harmed are solved, the accuracy and the feasibility of medicine package sealing performance detection are improved, and the technical effect of providing guiding basis for the production quality of a pharmaceutical factory is achieved.
As will be appreciated by one skilled in the art, embodiments of the present invention may be provided as a method, system, or computer program product. Accordingly, the present invention may take the form of an entirely hardware embodiment, an entirely software embodiment or an embodiment combining software and hardware aspects. Furthermore, the present invention may take the form of a computer program product embodied on one or more computer-usable storage media (including, but not limited to, disk storage, CD-ROM, optical storage, and the like) having computer-usable program code embodied therein.
The present invention is described with reference to flowchart illustrations and/or block diagrams of methods, apparatus (systems), and computer program products according to embodiments of the invention. It will be understood that each flow and/or block of the flow diagrams and/or block diagrams, and combinations of flows and/or blocks in the flow diagrams and/or block diagrams, can be implemented by computer program instructions. These computer program instructions may be provided to a processor of a general purpose computer, special purpose computer, embedded processor, or other programmable data processing apparatus to produce a machine, such that the instructions, which execute via the processor of the computer or other programmable data processing apparatus, create a system for implementing the functions specified in the flowchart flow or flows and/or block diagram block or blocks.
These computer program instructions may also be stored in a computer-readable memory that can direct a computer or other programmable data processing apparatus to function in a particular manner, such that the instructions stored in the computer-readable memory produce an article of manufacture including an instruction system which implement the function specified in the flowchart flow or flows and/or block diagram block or blocks.
These computer program instructions may also be loaded onto a computer or other programmable data processing apparatus to cause a series of operational steps to be performed on the computer or other programmable apparatus to produce a computer implemented process such that the instructions which execute on the computer or other programmable apparatus provide steps for implementing the functions specified in the flowchart flow or flows and/or block diagram block or blocks. While preferred embodiments of the present invention have been described, additional variations and modifications in those embodiments may occur to those skilled in the art once they learn of the basic inventive concepts. Therefore, it is intended that the appended claims be interpreted as including preferred embodiments and all such alterations and modifications as fall within the scope of the invention.
It will be apparent to those skilled in the art that various changes and modifications may be made in the present invention without departing from the spirit and scope of the invention. Thus, if such modifications and variations of the present invention fall within the scope of the claims of the present invention and their equivalents, the present invention is also intended to include such modifications and variations.

Claims (9)

1. A method of testing the hermeticity of a pharmaceutical package, wherein the method comprises:
obtaining drug category information for a first drug;
obtaining first production location information for the first drug;
obtaining first environmental air pressure information according to first production region information of the first medicine;
obtaining first use region information of the first medicine;
acquiring second environmental air pressure information according to the first using region information of the first medicine;
acquiring first air pressure difference information according to the first environmental air pressure information and the second environmental air pressure information;
inputting the medicine category information and the first air pressure difference information into a tightness detection model to obtain a first detection standard of the tightness of the first medicine;
obtaining sealability information of a first drug;
and judging whether the sealing performance information meets the first detection standard or not, and obtaining a first detection result.
2. The method of claim 1, wherein said inputting the drug class information and the first differential air pressure information into a seal tightness test model to obtain a first test criterion for the seal tightness of the first drug comprises:
inputting the medicine category information and the first air pressure difference information into a tightness detection model, wherein the tightness detection model is obtained by training a plurality of groups of training data, and each group of the plurality of groups of training data comprises: the drug category information, the first air pressure difference information and identification information identifying a first detection standard;
and obtaining a first output result of the tightness detection model, wherein the first output result comprises a first detection standard of the tightness of the first medicine.
3. The method of claim 1, wherein the obtaining the sealability information of the first drug product comprises:
obtaining sealing material information of the first drug;
obtaining the information of the internal and external pressure difference of the first medicine package;
and inputting the sealing material information of the first medicine and the internal and external pressure difference information of the first medicine package into a sealing detection model to obtain the sealing information of the first medicine.
4. The method of claim 3, wherein the method comprises:
obtaining a predetermined moisture resistance coefficient threshold;
obtaining a moisture resistance coefficient of a sealing material of the first pharmaceutical product;
judging whether the moisture-proof coefficient is within the preset moisture-proof coefficient threshold value or not to obtain a first weighted score;
and obtaining a second detection result according to the first weighted score and the first detection result.
5. The method of claim 4, wherein said determining whether said moisture barrier coefficient is within said predetermined moisture barrier coefficient threshold value, obtaining a first weighted score, comprises:
obtaining a first negative weighted score if the moisture resistance factor is not within the predetermined moisture resistance factor threshold;
obtaining a first positive weighted score if the moisture barrier coefficient is within the predetermined moisture barrier coefficient threshold.
6. The method of claim 4, wherein said obtaining a predetermined moisture resistance coefficient threshold comprises:
obtaining first humidity information of the first production region;
obtaining second humidity information of the first use region;
comparing the first humidity information with the second humidity information, and taking the maximum value to obtain third humidity information;
and obtaining a preset moisture-proof coefficient threshold value according to the third humidity information.
7. The method of claim 1, wherein the method comprises:
obtaining component information of the first drug;
judging whether the component information has photochemical reaction characteristics or not according to the component information of the first medicine;
if the component information has the photochemical reaction characteristic, obtaining the light-shielding grade of the sealing material of the first medicine;
obtaining a second weighted score according to the light-shielding grade of the first medicine sealing material;
and obtaining a third detection result according to the second weighted score and the first detection result.
8. An apparatus for testing the hermeticity of pharmaceutical packages, wherein the apparatus comprises:
a first obtaining unit for obtaining medicine category information of a first medicine;
a second obtaining unit for obtaining first production location information of the first medicine;
a third obtaining unit configured to obtain first ambient air pressure information based on first production location information of the first medicine;
a fourth obtaining unit, configured to obtain first usage region information of the first medicine;
a fifth obtaining unit, configured to obtain second ambient air pressure information according to the first usage region information of the first medicine;
a sixth obtaining unit, configured to obtain first air pressure difference information according to the first environmental air pressure information and the second environmental air pressure information;
a seventh obtaining unit, configured to input the medicine category information and the first air pressure difference information into a sealing performance detection model, and obtain a first detection criterion of sealing performance of the first medicine;
an eighth obtaining unit configured to obtain sealing information of the first medicine;
a ninth obtaining unit, configured to determine whether the sealing information meets the first detection criterion, and obtain a first detection result.
9. An apparatus for testing the sealability of pharmaceutical product packages comprising a memory, a processor and a computer program stored on the memory and executable on the processor, wherein the processor executes the program to perform the steps of the method according to any of claims 1-7.
CN202110051501.2A 2021-01-14 2021-01-14 Method and device for detecting medicine package tightness Pending CN112857709A (en)

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CN114636531A (en) * 2022-03-11 2022-06-17 四川省药品检验研究院(四川省医疗器械检测中心) Device and method for testing tightness of hard packaging container based on vacuum degree attenuation
CN116429976A (en) * 2023-04-19 2023-07-14 北京市永康药业有限公司 Injection production and packaging quality detection method and system

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CN108235762A (en) * 2016-10-12 2018-06-29 华为技术有限公司 A kind of detection method of sealing performance, device and storage medium

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CN114636531A (en) * 2022-03-11 2022-06-17 四川省药品检验研究院(四川省医疗器械检测中心) Device and method for testing tightness of hard packaging container based on vacuum degree attenuation
CN114636531B (en) * 2022-03-11 2024-02-27 四川省药品检验研究院(四川省医疗器械检测中心) Device and method for testing tightness of rigid packaging container based on vacuum degree attenuation
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CN116429976B (en) * 2023-04-19 2023-11-21 北京市永康药业有限公司 Injection production and packaging quality detection method and system

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Application publication date: 20210528