CN112827067A

CN112827067A - Transcranial magnetic stimulation coil and transcranial magnetic stimulation device

Info

Publication number: CN112827067A
Application number: CN202110219644.XA
Authority: CN
Inventors: 王欣; 殷涛; 刘志朋; 李颖; 王贺; 马任
Original assignee: Institute of Biomedical Engineering of CAMS and PUMC
Current assignee: Institute of Biomedical Engineering of CAMS and PUMC
Priority date: 2021-02-26
Filing date: 2021-02-26
Publication date: 2021-05-25

Abstract

The invention relates to the technical field of medical devices, and discloses a transcranial magnetic stimulation coil and a transcranial magnetic stimulation device. The transcranial magnetic stimulation coil includes a solenoid and a magnetic core. The solenoid comprises a tube body and a wire, wherein the tube body extends along a first axis, the wire of the tube body is spirally wound on the side wall of the tube body to form a coil, a first lateral line and a second lateral line which are parallel to and coplanar with the first axis are arranged on the tube body, the interval between every two adjacent coils of wire is gradually increased from the first lateral line to the second lateral line, and the projection of the end face of the first end of the tube body in a first plane is a straight line, is intersected with the first lateral line and is arranged in an acute angle. The magnetic core is arranged in the tube body and is arranged in the coil, the magnetic core extends along the second axis, the second axis is parallel to the first axis, the outer side wall of the magnetic core facing one side of the first lateral line is attached to the inner wall of the tube body, and the outer side wall of the magnetic core facing one side of the second lateral line is arranged at intervals with the inner wall of the tube body. The invention improves the focusing of the transcranial magnetic stimulation coil.

Description

Transcranial magnetic stimulation coil and transcranial magnetic stimulation device

Technical Field

The invention relates to the technical field of medical devices, in particular to a transcranial magnetic stimulation coil and a transcranial magnetic stimulation device.

Background

TRanscRanial Magnetic Stimulation (TMS) is a non-invasive medical device based on electromagnetic induction technology, and a pulsed Magnetic field is used for acting on a central nervous system to change the membrane potential of cerebral cortex nerve cells, so that induced current is generated to influence intracerebral metabolism and neuroelectric activity, thereby causing a series of physiological and biochemical reactions. It is widely used in various fields because of its painless, non-destructive and radiationless advantages. The stimulating coil is a load of a pulse current generating circuit and is made of a conductor with smaller resistivity, when the shapes of the coils are different, the distribution of the generated induced electric field is also different, and the focusing property is directly influenced, namely the size of the focusing area at the target point of the head of a patient is directly influenced, and the focusing property is higher when the focusing area is smaller under the condition of ensuring the magnetic field intensity. The design of the coil is critical in TMS studies. The high focusing property can reduce the stimulation range, enhance the pertinence to the stimulation of a target point of a patient and avoid stimulating irrelevant nerve tissues in the cranium, and the existing transcranial magnetic stimulation coil mainly takes a splayed coil and a circular coil as main parts, has larger magnetic field intensity, but has larger stimulation range at the head of the patient and poorer focusing degree, thereby influencing the treatment effect.

Based on this, there is a need for a transcranial magnetic stimulation coil and a transcranial magnetic stimulation device to solve the above-mentioned problems.

Disclosure of Invention

The invention aims to provide a transcranial magnetic stimulation coil and a transcranial magnetic stimulation device, which improve the focusing property of the transcranial magnetic stimulation coil and can stimulate the target area of the head of a patient in a targeted manner.

In order to achieve the purpose, the invention adopts the following technical scheme:

a transcranial magnetic stimulation coil comprising:

the solenoid comprises a tube body and a wire, wherein the tube body extends along a first axis, the wire is spirally wound on the side wall of the tube body to form a coil, a first lateral line and a second lateral line which are parallel to the first axis are arranged on the tube body, the first axis, the first lateral line and the second lateral line are all located in a first plane, the interval between every two adjacent turns of wire is gradually increased from the first lateral line to the second lateral line, and the projection of the end face of the first end of the tube body in the first plane is a straight line and is arranged at an acute angle with the first lateral line;

the magnetic core, the magnetic core is arranged in the body is inside and set up inside the coil, the magnetic core extends along the second axis, the second axis with first axis is parallel, just the magnetic core orientation the lateral wall of one side of first siding laminate in the inner wall of body, the magnetic core orientation the lateral wall of one side of second siding with the inner wall interval of body sets up.

Preferably, the pipe body comprises a first straight wall and a second straight wall, the first straight wall and the second straight wall are both parallel to the first axis, the first straight wall and the second straight wall are connected at an acute angle, and a connecting line between the first straight wall and the second straight wall is the first lateral line.

Preferably, the action end of the magnetic core is arranged towards the first end of the tube body, and the end face of the action end and the end face of the first end are in the same plane.

Preferably, a spiral winding groove is formed in the side wall of the pipe body, and the wire is placed in the winding groove.

Preferably, the tube body is a fan-shaped tube, and the magnetic core is a fan-shaped column.

Preferably, the transcranial magnetic stimulation coil further comprises a housing, the housing being wrapped outside the solenoid.

Preferably, the outer shell extends along the third axis, the first axis with third axis parallel arrangement, just the outer shell is followed both ends of third axis have all been sealed off the end plate, two the end plate all is perpendicular to the third axis.

Preferably, the housing is provided with a wire inlet hole for the wire to penetrate into the housing and a wire outlet hole for the wire to penetrate out of the housing.

Preferably, a cross-section of the housing perpendicular to the third axis is fan-shaped.

A transcranial magnetic stimulation device comprising a transcranial magnetic stimulation coil as described above.

The invention has the beneficial effects that:

when the medical tube is used, the first axis is perpendicular to the head of a patient, the first side line is guaranteed to pass through the target point of the head of the patient, the first end of the tube body is arranged towards the head of the patient, at the moment, the interval between two adjacent circles of wires in the first axis direction in the coil above the head of the patient is small, the interval between two adjacent circles of wires in the first axis direction is gradually increased from the first side line to the second side line, and the wires are wound tightly at the first side line. The magnetic field intensity at the target point is improved, so that the electric field intensity induced at the target point is improved, the stimulation intensity at the target point is increased, the second side line is located in the non-target area and is far away from the target point, and the magnetic field intensity of the non-target area is reduced, so that the electric field induced at the non-target area is weaker, the action area of the transcranial magnetic stimulation coil is limited near the target point, the action area of the transcranial magnetic stimulation coil is reduced, the focusing area is reduced, the focusing performance of the transcranial magnetic stimulation coil at the target point is improved, targeted treatment on the target point is facilitated, and the treatment effect is ensured. In addition, when the first end is arranged towards the patient, the coil at the first lateral line can be close to the head of the patient as far as possible, a certain distance exists between the coil at the second lateral line and the head of the patient, the distance is gradually increased from the first lateral line to the second lateral line, the attenuation degree of the magnetic field generated by the magnetic core and the coil at the first lateral line to the head is smaller, the attenuation degree of the magnetic field generated by the magnetic core and the coil at the second lateral line to the head is larger, the electric field induced at the target point is further ensured to be stronger, and the focusing performance is further improved. And the magnetic core is attached to the inner wall of the tube body corresponding to the first lateral line and is arranged at intervals with the inner wall of the tube body corresponding to the second lateral line, so that the magnetic field intensity generated by the coil at the first lateral line is further improved, the magnetic core is far away from a non-target area, the increase amplitude of the electric field intensity induced by the magnetic core to the non-target area corresponding to the second lateral line is reduced, and the focusing performance of the transcranial magnetic stimulation coil is further improved. The transcranial magnetic stimulation coil provided by the embodiment increases the stimulation intensity of a target point, weakens the stimulation intensity of a non-target area, enlarges the stimulation intensity difference of the target point between the non-target areas, and improves the focusing property of the transcranial magnetic stimulation coil.

Drawings

FIG. 1 is a cross-sectional view of a transcranial magnetic stimulation coil provided by an embodiment of the present invention;

FIG. 2 is a cross-sectional view of a transcranial magnetic stimulation coil provided by an embodiment of the present invention, taken along section A-A in FIG. 1;

fig. 3 is a structural diagram of a portion of a transcranial magnetic stimulation coil according to an embodiment of the invention.

In the figure:

1. a solenoid; 11. a pipe body; 111. a first straight wall; 112. a second straight wall; 113. a first cover; 114. a second cover; 12. a wire;

2. a magnetic core;

3. a housing; 31. an end plate;

4. a winding slot.

Detailed Description

In order to make the technical problems solved, technical solutions adopted and technical effects achieved by the present invention clearer, the technical solutions of the embodiments of the present invention will be described in further detail below with reference to the accompanying drawings, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

In the description of the present invention, unless expressly stated or limited otherwise, the terms "connected," "connected," and "fixed" are to be construed broadly, e.g., as meaning permanently connected, removably connected, or integral to one another; can be mechanically or electrically connected; either directly or indirectly through intervening media, either internally or in any other relationship. The specific meanings of the above terms in the present invention can be understood in specific cases to those skilled in the art.

In the present invention, unless otherwise expressly stated or limited, "above" or "below" a first feature means that the first and second features are in direct contact, or that the first and second features are not in direct contact but are in contact with each other via another feature therebetween. Also, the first feature being "on," "above" and "over" the second feature includes the first feature being directly on and obliquely above the second feature, or merely indicating that the first feature is at a higher level than the second feature. A first feature being "under," "below," and "beneath" a second feature includes the first feature being directly under and obliquely below the second feature, or simply meaning that the first feature is at a lesser elevation than the second feature.

The technical scheme of the invention is further explained by the specific implementation mode in combination with the attached drawings.

The present embodiments provide a transcranial magnetic stimulation coil. Specifically, as shown in fig. 1-3, a transcranial magnetic stimulation coil includes: a solenoid 1 and a core 2. The solenoid 1 comprises a tube body 11 and a lead 12, wherein the tube body 11 extends along a first axis, the lead 12 is spirally wound on the side wall of the tube body 11 to form a coil, a first lateral line and a second lateral line which are parallel to the first axis are arranged on the tube body 11, the first axis, the first lateral line and the second lateral line are all located in a first plane, the interval between two adjacent loops of the lead 12 is gradually increased from the first lateral line to the second lateral line, and the projection of the end surface of the first end of the tube body 11 in the first plane is a straight line, intersects with the first lateral line and is arranged in an acute angle. Inside magnetic core 2 arranged in body 11 and set up the coil, magnetic core 2 extended along the second axis, and the second axis is parallel with the first axis, and magnetic core 2 closed in the inner wall of body 11 towards the lateral wall of one side of first side line, and magnetic core 2 sets up towards the inner wall interval of lateral wall and body 11 of one side of second side line. In this embodiment, the projection of the end surface of the first end of the pipe 11 in the first plane forms an angle of 70 ° with the first side line. Specifically, the first end is located below the pipe body 11 with respect to the direction in fig. 2, and the first plane is an a-a section in fig. 1. It is understood that the magnetic core 2 is disposed within a range in which the wire 12 is wound to form a coil.

When using, first axis perpendicular to patient's head to guarantee the target point of first sideline process patient's head, and the first end of body 11 sets up towards patient's head, at this moment, be located the interval between the two adjacent circles of wire 12 in the coil of patient's head target point top and be little, and the interval between two adjacent circles of wire 12 is by first sideline to second sideline crescent, and wire 12 is comparatively inseparable in first sideline department winding promptly. The magnetic field intensity at the target point is improved, so that the electric field intensity induced at the target point is improved, the stimulation intensity at the target point is increased, the second side line is located in the non-target area and is far away from the target point, and the magnetic field intensity of the non-target area is reduced, so that the electric field induced at the non-target area is weaker, the action area of the transcranial magnetic stimulation coil is limited near the target point, the action area of the transcranial magnetic stimulation coil is reduced, the focusing area is reduced, the focusing performance of the transcranial magnetic stimulation coil at the target point is improved, targeted treatment on the target point is facilitated, and the treatment effect is ensured. In addition, when the first end is arranged towards the patient, the coil at the first lateral line can be close to the head of the patient as far as possible, a certain distance exists between the coil at the second lateral line and the head of the patient, the distance is gradually increased from the first lateral line to the second lateral line, the attenuation degree of the magnetic field generated by the magnetic core and the coil at the first lateral line to the head is smaller, the attenuation degree of the magnetic field generated by the magnetic core and the coil at the second lateral line to the head is larger, the electric field induced at the target point is further ensured to be stronger, and the focusing performance is further improved. And the magnetic core 2 is attached to the inner wall of the tube body 11 corresponding to the first lateral line and is arranged at an interval with the inner wall of the tube body 11 corresponding to the second lateral line, so that the magnetic field intensity generated by the coil at the first lateral line is further improved, the magnetic core 2 is far away from a non-target area, the increase amplitude of the electric field intensity induced by the magnetic core 2 to the non-target area corresponding to the second lateral line is reduced, and the focusing performance of the transcranial magnetic stimulation coil is further improved. The transcranial magnetic stimulation coil provided by the embodiment increases the stimulation intensity of a target point, weakens the stimulation intensity of a non-target area, enlarges the stimulation intensity difference of the target point between the non-target areas, and improves the focusing property of the transcranial magnetic stimulation coil.

In this embodiment, the magnetic core 2 is solid and made of silicon steel sheet, and the magnetic core 2 is fixed inside the tube 11 through an adhesive layer. And body 11 is provided with first closing cap 113 in first end department, has avoided magnetic core 2 and body 11 separation, has guaranteed the effect that magnetic core 2 strengthened magnetic field intensity. And the end of the tube 11 away from the first end is a second end, the end surface of the second end is parallel to the end surface of the first end, and a second cover 114 is disposed on the end surface of the second end. In other embodiments, the end surface of the second end may be disposed perpendicular to the first axis, and is not limited herein. In addition, the sealing caps at the two ends of the tube 11 and the tube 11 may be integrally arranged or separately arranged and connected by bonding or fastening.

Specifically, the tube 11 includes a first straight wall 111 and a second straight wall 112, both the first straight wall 111 and the second straight wall 112 are parallel to the first axis, the first straight wall 111 and the second straight wall 112 are connected in an acute angle, and a connection line between the first straight wall 111 and the second straight wall 112 is a first lateral line, and the first straight wall 111 and the second straight wall 112 connected in an acute angle are provided, so that a focusing area of a magnetic field generated by the corresponding lead 12 at the first lateral line is further reduced, focusing performance is improved, and targeted stimulation of a target point on the head of a patient is facilitated.

Further, the tube body 11 is a fan-shaped tube, and the magnetic core 2 is a fan-shaped column. For the cylindrical tube body 11 and the magnetic core 2, the region for inducing the electric field is still in a circular ring shape, so that the acting area at the target point is larger; the tube body 11 with the sector-shaped cross section and the magnetic core 2 are in a sector ring shape in the area where the electric field is induced on the head of the patient, and when the first side line is placed above the target point, namely the sharp point of the sector-shaped cross section is placed above the target point, the area of the electric field induced on the target point is reduced, and the focusing performance at the target point is improved. The radius of the sector of the section of the magnetic core 2 is 5mm, the included angle between two straight edges of the sector is 60 degrees, and the overall height along the first axis is 120 mm. The radius of the sector of the cross section of the tube body 11 is 10mm, the included angle between two straight edges of the sector is 60 degrees, and the overall height along the first axis is 120 mm. In other embodiments, the sizes of the tube 11 and the magnetic core 2 may be adjusted adaptively, and are not limited herein.

It can be understood that the first side line passes through the sharp point of the fan-shaped section of the tube body 11, and the two straight edges of the magnetic core 2 can be overlapped with the two straight edges of the tube body 11, so that the magnetic core 2 is convenient to position and mount, and the focusing performance is ensured. That is, the pipe 11 is provided with an arc-shaped surface at the second side line, and two ends of the arc-shaped surface are respectively connected with the first straight wall 111 and the second straight wall 112, so that the first straight wall 111, the arc-shaped surface and the second straight wall 112 are connected end to form a fan-shaped pipe. That is, since the first plane is the a-a section, a straight line where the a-a section intersects the arc-shaped surface is the second lateral line, and in fig. 2, the first lateral line is on the left side of fig. 2 and the second lateral line is on the right side of fig. 2. It can be understood that the first plane is sandwiched between the first straight wall 111 and the second straight wall 112, and the first plane intersects with the first straight wall 111 and the second straight wall 112 at a first lateral line, and the specific included angle between the first plane and the first straight wall 111 and the second straight wall 112 is the same, and is 30 °. The distance between the first axis and the first side line is the same as the distance between the first axis and the second side line.

In other embodiments, the cross-section of the tube 11 and the magnetic core 2 perpendicular to the first axis may also be triangular. That is, the pipe 11 is provided with a third straight wall at the second side line, and two ends of the third straight wall are respectively connected with the first straight wall 111 and the second straight wall 112, so that the first straight wall 111, the third straight wall and the second straight wall 112 are connected end to form a pipe shape with a triangular cross section.

Preferably, the active end of the magnetic core 2 is disposed toward the first end of the tube 11, and the end surface of the active end and the end surface of the first end are in the same plane. The magnetic core 2 is attached to the sealing cover towards the end face of one end of the sealing cover, so that the magnetic core 2 is convenient to place inside the pipe body 11, the magnetic core 2 is prevented from shaking inside the pipe body 11 when the transcranial magnetic stimulation coil is used, and the practicability is improved.

Preferably, the spiral winding groove 4 is formed in the side wall of the tube body 11, the wire 12 is arranged in the winding groove 4, the winding groove 4 is formed, the wire 12 is conveniently wound on the tube body 11 according to the winding groove 4, and the processing process is simplified.

In this embodiment, the width of the winding slot 4 is 2mm, the wire 12 is a 1mm enameled copper wire, a single wire 12 can be used to wind the tube 11, and a plurality of wires 12 can also wind the tube 11. The pipe body 11 is made of ABS resin or PVC plastic, and the winding grooves 4 can be formed in the pipe body 11 after the pipe body 11 is processed, or the winding grooves 4 can be formed in the printing process directly through 3D printing.

Specifically, the winding slot 4 is a multi-layer spiral structure along the first axis. The starting point of the winding of the wire 12 is taken as a first layer, each layer comprises three sections, the winding slot 4 reaches the arc-shaped surface along the fan-shaped straight edge corresponding to the first straight wall 111 at the starting point of the first section of the first layer, the second section of the first layer bypasses the arc-shaped surface, the plane of the wire 12 at the second section is vertical to the first axis, the third section of the first layer starts from the joint of the arc-shaped edge and the second straight wall 112 and reaches the sharp point of the fan-shaped section of the pipe body 11 along the second straight wall 112, and the end point of the third section is positioned above the starting point of the first section; the second, third, fourth and fifth winding grooves 4 are arranged in the same way as the first layer. The starting points of the winding grooves 4 at the first, second, third, fourth and fifth layers are respectively 3mm, 13mm, 23mm, 33mm and 43mm above the sharp point of the first end face of the tube body 11, that is, the winding grooves 4 are respectively 10mm apart from the starting points of the first, second, third, fourth and fifth layers. The end points of the winding grooves 4 at the first, second, third, fourth and fifth layers are respectively positioned 13mm, 23mm, 33mm, 43mm and 53mm above the sharp point of the first end face of the tube body 11, namely the end point of the winding groove 4 at the previous layer is the starting point of the winding groove 4 at the next layer, and the distance between the starting points of the winding grooves 4 at the two layers is 10 mm. The wires 12 of the first, second, third, fourth and fifth second segments of the winding grooves 4 are respectively positioned at the positions 23mm, 43mm, 63mm, 83mm and 103mm above the fan-shaped arc edge on the end surface of the first end, namely, the distance between the second segments of the two layers of winding grooves 4 is 20 mm. The winding of the winding groove 4 at the sharp point of the fan-shaped section is denser than that of the winding groove 4 at the arc-shaped side, and focusing is ensured.

Preferably, the transcranial magnetic stimulation coil further comprises a shell 3, the shell 3 is coated outside the solenoid 1, and the shell 3 is arranged to protect the solenoid 1, so that the durability of the solenoid 1 is improved, the lead 12 is prevented from being damaged, and the functionality of the transcranial magnetic stimulation coil is ensured.

Preferably, the housing 3 extends along a third axis, the first axis is parallel to the third axis, and the two ends of the housing 3 along the third axis are both sealed by end plates 31, and both end plates 31 are perpendicular to the third axis. The end plate 31 of shell 3 is mutually perpendicular with the third axis, can avoid the sharp portion of the first end terminal surface of body 11 to stab skin with end plate 31 and patient head contact, has improved the practicality. It will be appreciated that in order to ensure focussing of the transcranial magnetic stimulation coil, the end of the housing 3 near the end of the first cover 113 is directed towards the head of the patient when using the transcranial magnetic stimulation coil provided in this embodiment. In addition, when the transcranial magnetic stimulation coil provided by the embodiment is used, the interval between the end plate 31 and the head of the patient can be 1 mm.

Furthermore, the shell 3 is provided with a wire inlet hole for a wire 12 to penetrate into the shell 3 and a wire outlet hole for the wire 12 to penetrate out of the shell 3, and the wire inlet hole and the wire outlet hole are arranged, so that the wire 12 is conveniently connected with a power supply device, and the power supply to the coil is facilitated.

Preferably, the cross section of the housing 3 perpendicular to the third axis is sector-shaped. In this embodiment, the radius of the fan shape of the bottom surface of the housing 3 is larger than 10mm, the height is 120mm, and the material of the housing 3 is ABS resin. In other embodiments, the size of the housing 3 depends on the size of the coil 1 and is not limited thereto.

The present embodiments also provide a transcranial magnetic stimulation device. The transcranial magnetic stimulation device comprises a transcranial magnetic stimulation coil as above. The stimulation intensity to the target point is increased, the stimulation intensity to the non-target area is weakened, the stimulation intensity difference between the target point and the non-target area is enlarged, the targeted stimulation of the target point by the transcranial magnetic stimulation device is facilitated, and the treatment effect is ensured.

It should be understood that the above-described embodiments of the present invention are merely examples for clearly illustrating the present invention, and are not intended to limit the embodiments of the present invention. Other variations and modifications will be apparent to persons skilled in the art in light of the above description. And are neither required nor exhaustive of all embodiments. Any modification, equivalent replacement, and improvement made within the spirit and principle of the present invention should be included in the protection scope of the claims of the present invention.

Claims

1. A transcranial magnetic stimulation coil, comprising:

the solenoid (1) comprises a tube body (11) and a lead (12), wherein the tube body (11) extends along a first axis, the lead (12) is spirally wound on the side wall of the tube body (11) to form a coil, a first lateral line and a second lateral line which are parallel to the first axis are arranged on the tube body (11), the first axis, the first lateral line and the second lateral line are all located in a first plane, the interval between two adjacent turns of the lead (12) is gradually increased from the first lateral line to the second lateral line, and the projection of the end surface of the first end of the tube body (11) in the first plane is a straight line and is arranged at an acute angle with the first lateral line;

magnetic core (2), magnetic core (2) are arranged in body (11) and set up inside the coil, magnetic core (2) extend along the second axis, the second axis with first axis is parallel, just magnetic core (2) orientation the lateral wall of one side of first side line laminate in the inner wall of body (11), magnetic core (2) orientation the lateral wall of one side of second side line with the inner wall interval of body (11) sets up.

2. Transcranial magnetic stimulation coil according to claim 1, characterized in that the tube (11) comprises a first straight wall (111) and a second straight wall (112), the first straight wall (111) and the second straight wall (112) are both parallel to the first axis, the first straight wall (111) and the second straight wall (112) are connected at an acute angle and a connection line between the first straight wall (111) and the second straight wall (112) is the first lateral line.

3. Transcranial magnetic stimulation coil according to claim 1, characterized in that an active end of the magnetic core (2) is arranged towards the first end of the tube (11), an end face of the active end being in the same plane as an end face of the first end.

4. The transcranial magnetic stimulation coil according to claim 1, wherein the side wall of the tube body (11) is provided with a spiral winding groove (4), and the lead (12) is placed in the winding groove (4).

5. The transcranial magnetic stimulation coil according to claim 2, characterized in that the tube body (11) is a sector tube and the magnetic core (2) is a sector post.

6. Transcranial magnetic stimulation coil according to claim 5, characterized in that the transcranial magnetic stimulation coil further comprises a housing (3), the housing (3) being coated outside the solenoid (1).

7. The transcranial magnetic stimulation coil according to claim 6, characterized in that the outer shell (3) extends along a third axis, the first axis being arranged in parallel with the third axis, and that the outer shell (3) is closed at both ends along the third axis by end plates (31), both end plates (31) being perpendicular to the third axis.

8. The transcranial magnetic stimulation coil according to claim 6, wherein the housing (3) is provided with a wire inlet hole for the lead (12) to penetrate into the housing (3) and a wire outlet hole for the lead (12) to penetrate out of the housing (3).

9. The transcranial magnetic stimulation coil according to claim 7, characterized in that a cross-section of the housing (3) perpendicular to the third axis is fan-shaped.

10. A transcranial magnetic stimulation device comprising a transcranial magnetic stimulation coil according to any one of claims 1-9.