CN112827036A - Method and device for estimating air resistance and compliance of anesthesia machine - Google Patents
Method and device for estimating air resistance and compliance of anesthesia machine Download PDFInfo
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- 238000000034 method Methods 0.000 title claims abstract description 59
- 206010002091 Anaesthesia Diseases 0.000 title abstract description 13
- 230000037005 anaesthesia Effects 0.000 title abstract description 13
- 238000004458 analytical method Methods 0.000 claims abstract description 14
- 238000005070 sampling Methods 0.000 claims description 28
- 230000003434 inspiratory effect Effects 0.000 claims description 26
- 230000003444 anaesthetic effect Effects 0.000 claims description 7
- 230000029058 respiratory gaseous exchange Effects 0.000 claims description 7
- 238000009499 grossing Methods 0.000 claims 1
- 238000009423 ventilation Methods 0.000 description 14
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/021—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes operated by electrical means
- A61M16/022—Control means therefor
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/08—Detecting, measuring or recording devices for evaluating the respiratory organs
- A61B5/085—Measuring impedance of respiratory organs or lung elasticity
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
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- A61M2230/40—Respiratory characteristics
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Abstract
The invention belongs to the technical field of medical equipment, and particularly relates to a method for estimating the air resistance and compliance of an anesthesia respirator, which comprises the following steps: acquiring inspiration tidal volume, airway flow rate and inspiration pressure in the inspiration process in real time; acquiring estimated air pressure in the current acquisition period by using the real-time acquired inspiration tidal volume and the air channel flow rate; acquiring an estimated air pressure difference value by using the real-time acquired suction pressure and the acquired estimated air pressure in the current acquisition period; and estimating the air resistance and the compliance of the current acquisition period by adopting a binary regression linear analysis method according to the obtained estimated air pressure difference value.
Description
Technical Field
The invention belongs to the technical field of medical equipment, and particularly relates to a method and a device for estimating the air resistance and compliance of an anesthesia machine.
Background
Compliance and airway resistance are two important parameters in anesthesia machines. Through correct adjustment and monitoring of airway air resistance and compliance, the ventilation mode and ventilation parameters of the anesthesia machine can be effectively adjusted and controlled to adapt to different requirements. Because the ventilation process of the anesthesia machine can set different ventilation flow rates and ventilation time according to the two parameters, how to estimate accurate air resistance and compliance has great influence on the ventilation performance of the anesthesia machine.
At present, the compliance and the air resistance of the pipeline are difficult to directly calculate, and usually an estimation method in a VCV (volume control ventilation mode) mode is adopted to estimate the air resistance and the compliance of the pipeline according to formulas (1) and (2):
wherein, VinspIs the inspiratory tidal volume during inspiration; ppeakIs the inspiratory peak pressure during inspiration; pplatThe pressure of the ventilation platform in the process of inspiration; f. ofpeakIs the peak flow rate of the airway during inspiration; ppeepPositive end-expiratory pressure during inspiration;
however, this conventional estimation method can be performed only in the VCV mode, and there is a problem that the estimation accuracy of the estimated air resistance and compliance is low, and the ventilation performance of the anesthesia machine cannot be effectively expressed.
Disclosure of Invention
In order to solve the above-mentioned drawbacks of the prior art, the present invention provides a method for estimating the air resistance and compliance of an anesthetic breathing apparatus, the method comprising:
acquiring inspiration tidal volume, airway flow rate and inspiration pressure in the inspiration process in real time;
acquiring estimated air pressure in the current acquisition period by using the real-time acquired inspiration tidal volume and the air channel flow rate;
acquiring an estimated air pressure difference value by using the real-time acquired suction pressure and the acquired estimated air pressure in the current acquisition period;
and estimating the air resistance and the compliance of the current acquisition period by adopting a binary regression linear analysis method according to the obtained estimated air pressure difference value.
As one improvement of the above technical solution, the estimated air pressure in the current acquisition period is obtained by using the inspiratory tidal volume and the airway flow rate acquired in real time; the specific process comprises the following steps:
the method comprises the following steps of collecting the inspiration tidal volume and the airway flow rate in the inspiration process in real time, and calculating the estimated air pressure in the current period according to a formula (1):
wherein,the estimated air pressure in the current period is obtained;compliance for the current acquisition cycle; viThe tidal volume of inspiration in the ith sampling period in the inspiration process is acquired in real time;is the air resistance of the current acquisition period; fiIs the flow rate of the airway in the ith sampling period during inspiration acquired in real time.
As one improvement of the above technical solution, the estimated air pressure difference value is obtained by using the real-time acquired suction pressure and the obtained estimated air pressure in the current acquisition period; the specific process comprises the following steps:
calculating an estimated air pressure difference value based on the obtained estimated air pressure in the current acquisition period by using the real-time acquired suction pressure according to a formula (2):
wherein e isiIs an estimated air pressure difference value; piThe real-time acquisition of the inspiratory pressure in the ith sampling period in the inspiratory process;the estimated air pressure in the ith sampling period;compliance for the current acquisition cycle; viThe tidal volume of inspiration in the ith sampling period in the inspiration process is acquired in real time;is the air resistance of the current acquisition period; fiThe flow rate of the air passage in the ith sampling period in the real-time acquisition and inspiration process; n is the total number of sampling periods;
wherein, TinspIs the inspiration time during inspiration.
As one improvement of the technical scheme, the air resistance and the compliance of the current acquisition period are estimated by adopting a binary regression linear analysis method according to the obtained estimated air pressure difference value; the specific process comprises the following steps:
calculating the air resistance of the current acquisition period from the obtained estimated air pressure difference value by adopting a binary regression linear analysis methodPartial differential of (d):
determining compliance with respect to a current acquisition cycle for the obtained estimated barometric pressure differencePartial differential of (d):
in conjunction with equations (3) and (4) above, the compliance and resistance for the current cycle are estimated and derived:
the air resistance of the current acquisition period in the above equation is the best estimation value with the minimum error, and the compliance of the current acquisition period is the best estimation value with the minimum error.
The invention also provides a device for estimating the air resistance and compliance of an anesthesia respirator, which comprises:
the acquisition module is used for acquiring inspiratory tidal volume, airway flow rate and inspiratory pressure in an inspiratory process in real time;
the air pressure estimation module is used for acquiring estimated air pressure in the current acquisition period by utilizing the real-time acquired inspiration tidal volume and the air channel flow rate;
the difference value estimation module is used for acquiring an estimated air pressure difference value by utilizing the real-time acquired suction pressure and the acquired estimated air pressure in the current acquisition period; and
and the estimation module is used for estimating the air resistance and the compliance of the current acquisition period according to the obtained estimated air pressure difference value by adopting a binary regression linear analysis method.
Compared with the prior art, the invention has the beneficial effects that:
the method mainly depends on the relation among variables such as pressure, flow rate, volume, compliance, air resistance and the like in an airway mechanics formula, then estimates the air resistance and the compliance by utilizing data in the whole inspiration process, and the result obtained by the estimation method has small error and high estimation precision, is suitable for various ventilation modes and effectively embodies the ventilation performance of the anesthesia machine.
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FIG. 1 is a flow chart of a method of estimating the air resistance and compliance of an anesthetic breathing apparatus of the present invention.
Detailed Description
The invention will now be further described with reference to the accompanying drawings.
The invention provides a method for estimating the air resistance and compliance of an anesthesia respirator, which comprises the following steps:
acquiring inspiration tidal volume, airway flow rate and inspiration pressure in the inspiration process in real time;
acquiring estimated air pressure in the current acquisition period by using the real-time acquired inspiration tidal volume and the air channel flow rate;
specifically, the inspiratory tidal volume and the airway flow rate in the inspiratory process are collected in real time, and the estimated air pressure in the current period is calculated according to the formula (1):
wherein,the estimated air pressure in the current period is obtained;compliance for the current acquisition cycle; viThe tidal volume of inspiration in the ith sampling period in the inspiration process is acquired in real time;is the air resistance of the current acquisition period; fiIs the flow rate of the airway in the ith sampling period during inspiration acquired in real time.
Acquiring an estimated air pressure difference value by using the real-time acquired suction pressure and the acquired estimated air pressure in the current acquisition period;
specifically, the estimated air pressure difference value is calculated based on the obtained estimated air pressure in the current acquisition period by using the real-time acquired suction pressure according to the formula (2):
wherein e isiIs an estimated air pressure difference value; piThe real-time acquisition of the inspiratory pressure in the ith sampling period in the inspiratory process;the estimated air pressure in the ith sampling period;compliance for the current acquisition cycle; viThe tidal volume of inspiration in the ith sampling period in the inspiration process is acquired in real time;is the air resistance of the current acquisition period; fiThe flow rate of the air passage in the ith sampling period in the real-time acquisition and inspiration process; n is the total number of sampling periods;
wherein, TinspIs the inspiration time during inspiration.
And estimating the air resistance and the compliance of the current acquisition period by adopting a binary regression linear analysis method according to the obtained estimated air pressure difference value.
Specifically, a binary regression linear analysis method is adopted to calculate the air resistance of the current acquisition period according to the obtained estimated air pressure difference valuePartial differential of (d):
determining compliance with respect to a current acquisition cycle for the obtained estimated barometric pressure differencePartial differential of (d):
in conjunction with equations (3) and (4) above, the compliance and resistance for the current cycle are estimated and derived:
the air resistance of the current acquisition period in the above equation is the best estimation value with the minimum error, and the compliance of the current acquisition period is the best estimation value with the minimum error.
The invention also provides a device for estimating the air resistance and compliance of an anesthesia respirator, which comprises: the device comprises an acquisition module, an air pressure estimation module, a difference value estimation module and an estimation module;
the acquisition module is used for acquiring inspiratory tidal volume, airway flow rate and inspiratory pressure in an inspiratory process in real time;
the air pressure estimation module is used for acquiring estimated air pressure in the current acquisition period by utilizing the real-time acquired inspiration tidal volume and the air passage flow rate;
specifically, the inspiratory tidal volume and the airway flow rate in the inspiratory process are collected in real time, and the estimated air pressure in the current period is calculated according to the formula (1):
wherein,the estimated air pressure in the current period is obtained;compliance for the current acquisition cycle; viThe tidal volume of inspiration in the ith sampling period in the inspiration process is acquired in real time;is the air resistance of the current acquisition period; fiIs the flow rate of the airway in the ith sampling period during inspiration acquired in real time.
The difference value estimation module is used for acquiring an estimated air pressure difference value by utilizing the real-time acquired suction pressure and the acquired estimated air pressure in the current acquisition period;
specifically, the estimated air pressure difference value is calculated based on the obtained estimated air pressure in the current acquisition period by using the real-time acquired suction pressure according to the formula (2):
wherein e isiIs an estimated air pressure difference value; piThe real-time acquisition of the inspiratory pressure in the ith sampling period in the inspiratory process;the estimated air pressure in the ith sampling period;compliance for the current acquisition cycle; viThe tidal volume of inspiration in the ith sampling period in the inspiration process is acquired in real time;is the air resistance of the current acquisition period; fiThe flow rate of the air passage in the ith sampling period in the real-time acquisition and inspiration process; n is the total number of sampling periods;
wherein, TinspIs the inspiration time during inspiration.
And the estimation module is used for estimating the air resistance and the compliance of the current acquisition period according to the obtained estimated air pressure difference value by adopting a binary regression linear analysis method.
Specifically, a binary regression linear analysis method is adopted to calculate the air resistance of the current acquisition period according to the obtained estimated air pressure difference valuePartial differential of (d):
determining compliance with respect to a current acquisition cycle for the obtained estimated barometric pressure differencePartial differential of (d):
in conjunction with equations (3) and (4) above, the compliance and resistance for the current cycle are estimated and derived:
the air resistance of the current acquisition period in the above equation is the best estimation value with the minimum error, and the compliance of the current acquisition period is the best estimation value with the minimum error.
The method is not limited by the ventilation mode, and can accurately estimate the air resistance and the compliance in any ventilation mode; the data used by the method is not ventilation data at a single moment, but the data of the whole process from the beginning of inspiration to the end of inspiration, and the calculated result is closer to the actual situation; a binary regression linear analysis method is used, so that the error of a calculation result is minimum and is closest to a true value; and the efficiency is improved while the accurate result is calculated.
Finally, it should be noted that the above embodiments are only used for illustrating the technical solutions of the present invention and are not limited. Although the present invention has been described in detail with reference to the embodiments, it will be understood by those skilled in the art that various changes may be made and equivalents may be substituted without departing from the spirit and scope of the invention as defined in the appended claims.
Claims (5)
1. A method of estimating the air resistance and compliance of an anesthetic breathing apparatus, the method comprising:
acquiring inspiration tidal volume, airway flow rate and inspiration pressure in the inspiration process in real time;
acquiring estimated air pressure in the current acquisition period by using the real-time acquired inspiration tidal volume and the air channel flow rate;
acquiring an estimated air pressure difference value by using the real-time acquired suction pressure and the acquired estimated air pressure in the current acquisition period;
and estimating the air resistance and the compliance of the current acquisition period by adopting a binary regression linear analysis method according to the obtained estimated air pressure difference value.
2. The method of estimating the air resistance and compliance of an anesthetic breathing apparatus as claimed in claim 1, wherein the estimated air pressure in the current acquisition period is obtained by using the inspiratory tidal volume and airway flow rate acquired in real time; the specific process comprises the following steps:
the method comprises the following steps of collecting the inspiration tidal volume and the airway flow rate in the inspiration process in real time, and calculating the estimated air pressure in the current period according to a formula (1):
wherein,the estimated air pressure in the current period is obtained;compliance for the current acquisition cycle; viThe tidal volume of inspiration in the ith sampling period in the inspiration process is acquired in real time;is the air resistance of the current acquisition period; fiIs the flow rate of the airway in the ith sampling period during inspiration acquired in real time.
3. The method of estimating the air resistance and compliance of an anesthetic breathing apparatus as claimed in claim 1, wherein the estimated air pressure difference is obtained using the real-time acquired inspiratory pressure and the obtained estimated air pressure in the current acquisition period; the specific process comprises the following steps:
calculating an estimated air pressure difference value based on the obtained estimated air pressure in the current acquisition period by using the real-time acquired suction pressure according to a formula (2):
wherein e isiIs an estimated air pressure difference value; piThe real-time acquisition of the inspiratory pressure in the ith sampling period in the inspiratory process;the estimated air pressure in the ith sampling period;compliance for the current acquisition cycle; viThe tidal volume of inspiration in the ith sampling period in the inspiration process is acquired in real time;is the air resistance of the current acquisition period; fiThe flow rate of the air passage in the ith sampling period in the real-time acquisition and inspiration process; n is the total number of sampling periods;
wherein, TinspIs the inspiration time during inspiration.
4. The method of claim 1, wherein the method of estimating the air resistance and compliance of the anesthetic breathing apparatus comprises estimating the air resistance and compliance of the current acquisition cycle based on the obtained estimated air pressure difference value by using a binary regression linear analysis method; the specific process comprises the following steps:
calculating the air resistance of the current acquisition period from the obtained estimated air pressure difference value by adopting a binary regression linear analysis methodPartial differential of (d):
smoothing the obtained estimated air pressure difference value with respect to the current acquisition periodStress responsePartial differential of (d):
in conjunction with equations (3) and (4) above, the compliance and resistance for the current cycle are estimated and derived:
the air resistance of the current acquisition period in the above equation is the best estimation value with the minimum error, and the compliance of the current acquisition period is the best estimation value with the minimum error.
5. An apparatus for estimating the air resistance and compliance of an anesthetic breathing apparatus, the apparatus comprising:
the acquisition module is used for acquiring inspiratory tidal volume, airway flow rate and inspiratory pressure in an inspiratory process in real time;
the air pressure estimation module is used for acquiring estimated air pressure in the current acquisition period by utilizing the real-time acquired inspiration tidal volume and the air channel flow rate;
the difference value estimation module is used for acquiring an estimated air pressure difference value by utilizing the real-time acquired suction pressure and the acquired estimated air pressure in the current acquisition period; and
and the estimation module is used for estimating the air resistance and the compliance of the current acquisition period according to the obtained estimated air pressure difference value by adopting a binary regression linear analysis method.
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Citations (7)
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GB2077444A (en) * | 1980-06-06 | 1981-12-16 | Draegerwerk Ag | Determining at least two parameters of a patient's respiratory system |
US6068602A (en) * | 1997-09-26 | 2000-05-30 | Ohmeda Inc. | Method and apparatus for determining airway resistance and lung compliance |
US6390091B1 (en) * | 1999-02-03 | 2002-05-21 | University Of Florida | Method and apparatus for controlling a medical ventilator |
CN104874059A (en) * | 2014-02-28 | 2015-09-02 | 北京谊安医疗系统股份有限公司 | Respirator pressure control method and system |
CN105078462A (en) * | 2015-05-27 | 2015-11-25 | 深圳市科曼医疗设备有限公司 | Method and device for estimating air resistant and compliance |
CN108066872A (en) * | 2016-11-16 | 2018-05-25 | 北京航天长峰股份有限公司 | A kind of monitoring method of anesthesia respirator dynamic vapour lock and compliance |
CN111249588A (en) * | 2020-01-20 | 2020-06-09 | 深圳市科曼医疗设备有限公司 | Expiratory pressure control method, device and equipment based on breathing machine and storage medium |
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- 2020-12-31 CN CN202011636645.6A patent/CN112827036A/en active Pending
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2077444A (en) * | 1980-06-06 | 1981-12-16 | Draegerwerk Ag | Determining at least two parameters of a patient's respiratory system |
US6068602A (en) * | 1997-09-26 | 2000-05-30 | Ohmeda Inc. | Method and apparatus for determining airway resistance and lung compliance |
US6390091B1 (en) * | 1999-02-03 | 2002-05-21 | University Of Florida | Method and apparatus for controlling a medical ventilator |
CN104874059A (en) * | 2014-02-28 | 2015-09-02 | 北京谊安医疗系统股份有限公司 | Respirator pressure control method and system |
CN105078462A (en) * | 2015-05-27 | 2015-11-25 | 深圳市科曼医疗设备有限公司 | Method and device for estimating air resistant and compliance |
CN108066872A (en) * | 2016-11-16 | 2018-05-25 | 北京航天长峰股份有限公司 | A kind of monitoring method of anesthesia respirator dynamic vapour lock and compliance |
CN111249588A (en) * | 2020-01-20 | 2020-06-09 | 深圳市科曼医疗设备有限公司 | Expiratory pressure control method, device and equipment based on breathing machine and storage medium |
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