CN112827036A - Method and device for estimating air resistance and compliance of anesthesia machine - Google Patents

Method and device for estimating air resistance and compliance of anesthesia machine Download PDF

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CN112827036A
CN112827036A CN202011636645.6A CN202011636645A CN112827036A CN 112827036 A CN112827036 A CN 112827036A CN 202011636645 A CN202011636645 A CN 202011636645A CN 112827036 A CN112827036 A CN 112827036A
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air pressure
inspiration
current acquisition
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estimated air
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李洪祥
宋恒利
吴艳美
成杰
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Beijing Aeonmed Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/021Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes operated by electrical means
    • A61M16/022Control means therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/08Detecting, measuring or recording devices for evaluating the respiratory organs
    • A61B5/085Measuring impedance of respiratory organs or lung elasticity
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/0003Accessories therefor, e.g. sensors, vibrators, negative pressure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2230/00Measuring parameters of the user
    • A61M2230/40Respiratory characteristics

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Abstract

The invention belongs to the technical field of medical equipment, and particularly relates to a method for estimating the air resistance and compliance of an anesthesia respirator, which comprises the following steps: acquiring inspiration tidal volume, airway flow rate and inspiration pressure in the inspiration process in real time; acquiring estimated air pressure in the current acquisition period by using the real-time acquired inspiration tidal volume and the air channel flow rate; acquiring an estimated air pressure difference value by using the real-time acquired suction pressure and the acquired estimated air pressure in the current acquisition period; and estimating the air resistance and the compliance of the current acquisition period by adopting a binary regression linear analysis method according to the obtained estimated air pressure difference value.

Description

Method and device for estimating air resistance and compliance of anesthesia machine
Technical Field
The invention belongs to the technical field of medical equipment, and particularly relates to a method and a device for estimating the air resistance and compliance of an anesthesia machine.
Background
Compliance and airway resistance are two important parameters in anesthesia machines. Through correct adjustment and monitoring of airway air resistance and compliance, the ventilation mode and ventilation parameters of the anesthesia machine can be effectively adjusted and controlled to adapt to different requirements. Because the ventilation process of the anesthesia machine can set different ventilation flow rates and ventilation time according to the two parameters, how to estimate accurate air resistance and compliance has great influence on the ventilation performance of the anesthesia machine.
At present, the compliance and the air resistance of the pipeline are difficult to directly calculate, and usually an estimation method in a VCV (volume control ventilation mode) mode is adopted to estimate the air resistance and the compliance of the pipeline according to formulas (1) and (2):
Figure BDA0002878637430000011
Figure BDA0002878637430000012
wherein, VinspIs the inspiratory tidal volume during inspiration; ppeakIs the inspiratory peak pressure during inspiration; pplatThe pressure of the ventilation platform in the process of inspiration; f. ofpeakIs the peak flow rate of the airway during inspiration; ppeepPositive end-expiratory pressure during inspiration;
however, this conventional estimation method can be performed only in the VCV mode, and there is a problem that the estimation accuracy of the estimated air resistance and compliance is low, and the ventilation performance of the anesthesia machine cannot be effectively expressed.
Disclosure of Invention
In order to solve the above-mentioned drawbacks of the prior art, the present invention provides a method for estimating the air resistance and compliance of an anesthetic breathing apparatus, the method comprising:
acquiring inspiration tidal volume, airway flow rate and inspiration pressure in the inspiration process in real time;
acquiring estimated air pressure in the current acquisition period by using the real-time acquired inspiration tidal volume and the air channel flow rate;
acquiring an estimated air pressure difference value by using the real-time acquired suction pressure and the acquired estimated air pressure in the current acquisition period;
and estimating the air resistance and the compliance of the current acquisition period by adopting a binary regression linear analysis method according to the obtained estimated air pressure difference value.
As one improvement of the above technical solution, the estimated air pressure in the current acquisition period is obtained by using the inspiratory tidal volume and the airway flow rate acquired in real time; the specific process comprises the following steps:
the method comprises the following steps of collecting the inspiration tidal volume and the airway flow rate in the inspiration process in real time, and calculating the estimated air pressure in the current period according to a formula (1):
Figure BDA0002878637430000021
wherein,
Figure BDA0002878637430000022
the estimated air pressure in the current period is obtained;
Figure BDA0002878637430000023
compliance for the current acquisition cycle; viThe tidal volume of inspiration in the ith sampling period in the inspiration process is acquired in real time;
Figure BDA0002878637430000024
is the air resistance of the current acquisition period; fiIs the flow rate of the airway in the ith sampling period during inspiration acquired in real time.
As one improvement of the above technical solution, the estimated air pressure difference value is obtained by using the real-time acquired suction pressure and the obtained estimated air pressure in the current acquisition period; the specific process comprises the following steps:
calculating an estimated air pressure difference value based on the obtained estimated air pressure in the current acquisition period by using the real-time acquired suction pressure according to a formula (2):
Figure BDA0002878637430000025
wherein e isiIs an estimated air pressure difference value; piThe real-time acquisition of the inspiratory pressure in the ith sampling period in the inspiratory process;
Figure BDA0002878637430000026
the estimated air pressure in the ith sampling period;
Figure BDA0002878637430000027
compliance for the current acquisition cycle; viThe tidal volume of inspiration in the ith sampling period in the inspiration process is acquired in real time;
Figure BDA0002878637430000028
is the air resistance of the current acquisition period; fiThe flow rate of the air passage in the ith sampling period in the real-time acquisition and inspiration process; n is the total number of sampling periods;
wherein,
Figure BDA0002878637430000029
wherein, TinspIs the inspiration time during inspiration.
As one improvement of the technical scheme, the air resistance and the compliance of the current acquisition period are estimated by adopting a binary regression linear analysis method according to the obtained estimated air pressure difference value; the specific process comprises the following steps:
calculating the air resistance of the current acquisition period from the obtained estimated air pressure difference value by adopting a binary regression linear analysis method
Figure BDA0002878637430000031
Partial differential of (d):
Figure BDA0002878637430000032
determining compliance with respect to a current acquisition cycle for the obtained estimated barometric pressure difference
Figure BDA0002878637430000033
Partial differential of (d):
Figure BDA0002878637430000034
in conjunction with equations (3) and (4) above, the compliance and resistance for the current cycle are estimated and derived:
Figure BDA0002878637430000035
Figure BDA0002878637430000036
the air resistance of the current acquisition period in the above equation is the best estimation value with the minimum error, and the compliance of the current acquisition period is the best estimation value with the minimum error.
The invention also provides a device for estimating the air resistance and compliance of an anesthesia respirator, which comprises:
the acquisition module is used for acquiring inspiratory tidal volume, airway flow rate and inspiratory pressure in an inspiratory process in real time;
the air pressure estimation module is used for acquiring estimated air pressure in the current acquisition period by utilizing the real-time acquired inspiration tidal volume and the air channel flow rate;
the difference value estimation module is used for acquiring an estimated air pressure difference value by utilizing the real-time acquired suction pressure and the acquired estimated air pressure in the current acquisition period; and
and the estimation module is used for estimating the air resistance and the compliance of the current acquisition period according to the obtained estimated air pressure difference value by adopting a binary regression linear analysis method.
Compared with the prior art, the invention has the beneficial effects that:
the method mainly depends on the relation among variables such as pressure, flow rate, volume, compliance, air resistance and the like in an airway mechanics formula, then estimates the air resistance and the compliance by utilizing data in the whole inspiration process, and the result obtained by the estimation method has small error and high estimation precision, is suitable for various ventilation modes and effectively embodies the ventilation performance of the anesthesia machine.
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FIG. 1 is a flow chart of a method of estimating the air resistance and compliance of an anesthetic breathing apparatus of the present invention.
Detailed Description
The invention will now be further described with reference to the accompanying drawings.
The invention provides a method for estimating the air resistance and compliance of an anesthesia respirator, which comprises the following steps:
acquiring inspiration tidal volume, airway flow rate and inspiration pressure in the inspiration process in real time;
acquiring estimated air pressure in the current acquisition period by using the real-time acquired inspiration tidal volume and the air channel flow rate;
specifically, the inspiratory tidal volume and the airway flow rate in the inspiratory process are collected in real time, and the estimated air pressure in the current period is calculated according to the formula (1):
Figure BDA0002878637430000041
wherein,
Figure BDA0002878637430000042
the estimated air pressure in the current period is obtained;
Figure BDA0002878637430000043
compliance for the current acquisition cycle; viThe tidal volume of inspiration in the ith sampling period in the inspiration process is acquired in real time;
Figure BDA0002878637430000044
is the air resistance of the current acquisition period; fiIs the flow rate of the airway in the ith sampling period during inspiration acquired in real time.
Acquiring an estimated air pressure difference value by using the real-time acquired suction pressure and the acquired estimated air pressure in the current acquisition period;
specifically, the estimated air pressure difference value is calculated based on the obtained estimated air pressure in the current acquisition period by using the real-time acquired suction pressure according to the formula (2):
Figure BDA0002878637430000045
wherein e isiIs an estimated air pressure difference value; piThe real-time acquisition of the inspiratory pressure in the ith sampling period in the inspiratory process;
Figure BDA0002878637430000046
the estimated air pressure in the ith sampling period;
Figure BDA0002878637430000047
compliance for the current acquisition cycle; viThe tidal volume of inspiration in the ith sampling period in the inspiration process is acquired in real time;
Figure BDA0002878637430000048
is the air resistance of the current acquisition period; fiThe flow rate of the air passage in the ith sampling period in the real-time acquisition and inspiration process; n is the total number of sampling periods;
wherein,
Figure BDA0002878637430000051
wherein, TinspIs the inspiration time during inspiration.
And estimating the air resistance and the compliance of the current acquisition period by adopting a binary regression linear analysis method according to the obtained estimated air pressure difference value.
Specifically, a binary regression linear analysis method is adopted to calculate the air resistance of the current acquisition period according to the obtained estimated air pressure difference value
Figure BDA0002878637430000052
Partial differential of (d):
Figure BDA0002878637430000053
determining compliance with respect to a current acquisition cycle for the obtained estimated barometric pressure difference
Figure BDA0002878637430000054
Partial differential of (d):
Figure BDA0002878637430000055
in conjunction with equations (3) and (4) above, the compliance and resistance for the current cycle are estimated and derived:
Figure BDA0002878637430000056
Figure BDA0002878637430000057
the air resistance of the current acquisition period in the above equation is the best estimation value with the minimum error, and the compliance of the current acquisition period is the best estimation value with the minimum error.
The invention also provides a device for estimating the air resistance and compliance of an anesthesia respirator, which comprises: the device comprises an acquisition module, an air pressure estimation module, a difference value estimation module and an estimation module;
the acquisition module is used for acquiring inspiratory tidal volume, airway flow rate and inspiratory pressure in an inspiratory process in real time;
the air pressure estimation module is used for acquiring estimated air pressure in the current acquisition period by utilizing the real-time acquired inspiration tidal volume and the air passage flow rate;
specifically, the inspiratory tidal volume and the airway flow rate in the inspiratory process are collected in real time, and the estimated air pressure in the current period is calculated according to the formula (1):
Figure BDA0002878637430000061
wherein,
Figure BDA0002878637430000062
the estimated air pressure in the current period is obtained;
Figure BDA0002878637430000063
compliance for the current acquisition cycle; viThe tidal volume of inspiration in the ith sampling period in the inspiration process is acquired in real time;
Figure BDA0002878637430000064
is the air resistance of the current acquisition period; fiIs the flow rate of the airway in the ith sampling period during inspiration acquired in real time.
The difference value estimation module is used for acquiring an estimated air pressure difference value by utilizing the real-time acquired suction pressure and the acquired estimated air pressure in the current acquisition period;
specifically, the estimated air pressure difference value is calculated based on the obtained estimated air pressure in the current acquisition period by using the real-time acquired suction pressure according to the formula (2):
Figure BDA0002878637430000065
wherein e isiIs an estimated air pressure difference value; piThe real-time acquisition of the inspiratory pressure in the ith sampling period in the inspiratory process;
Figure BDA0002878637430000066
the estimated air pressure in the ith sampling period;
Figure BDA0002878637430000067
compliance for the current acquisition cycle; viThe tidal volume of inspiration in the ith sampling period in the inspiration process is acquired in real time;
Figure BDA0002878637430000068
is the air resistance of the current acquisition period; fiThe flow rate of the air passage in the ith sampling period in the real-time acquisition and inspiration process; n is the total number of sampling periods;
wherein,
Figure BDA0002878637430000069
wherein, TinspIs the inspiration time during inspiration.
And the estimation module is used for estimating the air resistance and the compliance of the current acquisition period according to the obtained estimated air pressure difference value by adopting a binary regression linear analysis method.
Specifically, a binary regression linear analysis method is adopted to calculate the air resistance of the current acquisition period according to the obtained estimated air pressure difference value
Figure BDA00028786374300000610
Partial differential of (d):
Figure BDA00028786374300000611
determining compliance with respect to a current acquisition cycle for the obtained estimated barometric pressure difference
Figure BDA00028786374300000612
Partial differential of (d):
Figure BDA0002878637430000071
in conjunction with equations (3) and (4) above, the compliance and resistance for the current cycle are estimated and derived:
Figure BDA0002878637430000072
Figure BDA0002878637430000073
the air resistance of the current acquisition period in the above equation is the best estimation value with the minimum error, and the compliance of the current acquisition period is the best estimation value with the minimum error.
The method is not limited by the ventilation mode, and can accurately estimate the air resistance and the compliance in any ventilation mode; the data used by the method is not ventilation data at a single moment, but the data of the whole process from the beginning of inspiration to the end of inspiration, and the calculated result is closer to the actual situation; a binary regression linear analysis method is used, so that the error of a calculation result is minimum and is closest to a true value; and the efficiency is improved while the accurate result is calculated.
Finally, it should be noted that the above embodiments are only used for illustrating the technical solutions of the present invention and are not limited. Although the present invention has been described in detail with reference to the embodiments, it will be understood by those skilled in the art that various changes may be made and equivalents may be substituted without departing from the spirit and scope of the invention as defined in the appended claims.

Claims (5)

1. A method of estimating the air resistance and compliance of an anesthetic breathing apparatus, the method comprising:
acquiring inspiration tidal volume, airway flow rate and inspiration pressure in the inspiration process in real time;
acquiring estimated air pressure in the current acquisition period by using the real-time acquired inspiration tidal volume and the air channel flow rate;
acquiring an estimated air pressure difference value by using the real-time acquired suction pressure and the acquired estimated air pressure in the current acquisition period;
and estimating the air resistance and the compliance of the current acquisition period by adopting a binary regression linear analysis method according to the obtained estimated air pressure difference value.
2. The method of estimating the air resistance and compliance of an anesthetic breathing apparatus as claimed in claim 1, wherein the estimated air pressure in the current acquisition period is obtained by using the inspiratory tidal volume and airway flow rate acquired in real time; the specific process comprises the following steps:
the method comprises the following steps of collecting the inspiration tidal volume and the airway flow rate in the inspiration process in real time, and calculating the estimated air pressure in the current period according to a formula (1):
Figure FDA0002878637420000011
wherein,
Figure FDA0002878637420000012
the estimated air pressure in the current period is obtained;
Figure FDA0002878637420000013
compliance for the current acquisition cycle; viThe tidal volume of inspiration in the ith sampling period in the inspiration process is acquired in real time;
Figure FDA0002878637420000014
is the air resistance of the current acquisition period; fiIs the flow rate of the airway in the ith sampling period during inspiration acquired in real time.
3. The method of estimating the air resistance and compliance of an anesthetic breathing apparatus as claimed in claim 1, wherein the estimated air pressure difference is obtained using the real-time acquired inspiratory pressure and the obtained estimated air pressure in the current acquisition period; the specific process comprises the following steps:
calculating an estimated air pressure difference value based on the obtained estimated air pressure in the current acquisition period by using the real-time acquired suction pressure according to a formula (2):
Figure FDA0002878637420000015
wherein e isiIs an estimated air pressure difference value; piThe real-time acquisition of the inspiratory pressure in the ith sampling period in the inspiratory process;
Figure FDA0002878637420000016
the estimated air pressure in the ith sampling period;
Figure FDA0002878637420000017
compliance for the current acquisition cycle; viThe tidal volume of inspiration in the ith sampling period in the inspiration process is acquired in real time;
Figure FDA0002878637420000018
is the air resistance of the current acquisition period; fiThe flow rate of the air passage in the ith sampling period in the real-time acquisition and inspiration process; n is the total number of sampling periods;
wherein,
Figure FDA0002878637420000021
wherein, TinspIs the inspiration time during inspiration.
4. The method of claim 1, wherein the method of estimating the air resistance and compliance of the anesthetic breathing apparatus comprises estimating the air resistance and compliance of the current acquisition cycle based on the obtained estimated air pressure difference value by using a binary regression linear analysis method; the specific process comprises the following steps:
calculating the air resistance of the current acquisition period from the obtained estimated air pressure difference value by adopting a binary regression linear analysis method
Figure FDA0002878637420000022
Partial differential of (d):
Figure FDA0002878637420000023
smoothing the obtained estimated air pressure difference value with respect to the current acquisition periodStress response
Figure FDA0002878637420000024
Partial differential of (d):
Figure FDA0002878637420000025
in conjunction with equations (3) and (4) above, the compliance and resistance for the current cycle are estimated and derived:
Figure FDA0002878637420000026
Figure FDA0002878637420000027
the air resistance of the current acquisition period in the above equation is the best estimation value with the minimum error, and the compliance of the current acquisition period is the best estimation value with the minimum error.
5. An apparatus for estimating the air resistance and compliance of an anesthetic breathing apparatus, the apparatus comprising:
the acquisition module is used for acquiring inspiratory tidal volume, airway flow rate and inspiratory pressure in an inspiratory process in real time;
the air pressure estimation module is used for acquiring estimated air pressure in the current acquisition period by utilizing the real-time acquired inspiration tidal volume and the air channel flow rate;
the difference value estimation module is used for acquiring an estimated air pressure difference value by utilizing the real-time acquired suction pressure and the acquired estimated air pressure in the current acquisition period; and
and the estimation module is used for estimating the air resistance and the compliance of the current acquisition period according to the obtained estimated air pressure difference value by adopting a binary regression linear analysis method.
CN202011636645.6A 2020-12-31 2020-12-31 Method and device for estimating air resistance and compliance of anesthesia machine Pending CN112827036A (en)

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Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2077444A (en) * 1980-06-06 1981-12-16 Draegerwerk Ag Determining at least two parameters of a patient's respiratory system
US6068602A (en) * 1997-09-26 2000-05-30 Ohmeda Inc. Method and apparatus for determining airway resistance and lung compliance
US6390091B1 (en) * 1999-02-03 2002-05-21 University Of Florida Method and apparatus for controlling a medical ventilator
CN104874059A (en) * 2014-02-28 2015-09-02 北京谊安医疗系统股份有限公司 Respirator pressure control method and system
CN105078462A (en) * 2015-05-27 2015-11-25 深圳市科曼医疗设备有限公司 Method and device for estimating air resistant and compliance
CN108066872A (en) * 2016-11-16 2018-05-25 北京航天长峰股份有限公司 A kind of monitoring method of anesthesia respirator dynamic vapour lock and compliance
CN111249588A (en) * 2020-01-20 2020-06-09 深圳市科曼医疗设备有限公司 Expiratory pressure control method, device and equipment based on breathing machine and storage medium

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2077444A (en) * 1980-06-06 1981-12-16 Draegerwerk Ag Determining at least two parameters of a patient's respiratory system
US6068602A (en) * 1997-09-26 2000-05-30 Ohmeda Inc. Method and apparatus for determining airway resistance and lung compliance
US6390091B1 (en) * 1999-02-03 2002-05-21 University Of Florida Method and apparatus for controlling a medical ventilator
CN104874059A (en) * 2014-02-28 2015-09-02 北京谊安医疗系统股份有限公司 Respirator pressure control method and system
CN105078462A (en) * 2015-05-27 2015-11-25 深圳市科曼医疗设备有限公司 Method and device for estimating air resistant and compliance
CN108066872A (en) * 2016-11-16 2018-05-25 北京航天长峰股份有限公司 A kind of monitoring method of anesthesia respirator dynamic vapour lock and compliance
CN111249588A (en) * 2020-01-20 2020-06-09 深圳市科曼医疗设备有限公司 Expiratory pressure control method, device and equipment based on breathing machine and storage medium

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