CN112816275B - Brain repair device - Google Patents
Brain repair device Download PDFInfo
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- CN112816275B CN112816275B CN201911127473.7A CN201911127473A CN112816275B CN 112816275 B CN112816275 B CN 112816275B CN 201911127473 A CN201911127473 A CN 201911127473A CN 112816275 B CN112816275 B CN 112816275B
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- brain
- blade
- block
- clamping seat
- repair
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/286—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B26—HAND CUTTING TOOLS; CUTTING; SEVERING
- B26B—HAND-HELD CUTTING TOOLS NOT OTHERWISE PROVIDED FOR
- B26B3/00—Hand knives with fixed blades
- B26B3/04—Hand knives with fixed blades for performing several incisions simultaneously; Multiple-blade knives
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/02—Devices for withdrawing samples
- G01N1/04—Devices for withdrawing samples in the solid state, e.g. by cutting
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/286—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
- G01N2001/2873—Cutting or cleaving
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- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Pathology (AREA)
- Forests & Forestry (AREA)
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Magnetic Treatment Devices (AREA)
- Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
Abstract
The invention provides a brain repair block device, which is applied to a murine brain repair block and comprises the following components: a metal clamping seat and one or more blades; the back of the blade is provided with magnetism, and the back of the blade is connected with the clamping seat through magnetic attraction. Through the characteristic of magnetic attraction, the blade and the clamping seat can be quickly combined as required, the mouse brain block repairing operation can be quickly carried out, and the block repairing can be accurately finished in a very short time; the operation is simple and convenient, the combination is flexible, and the brain block repairing operation of various shapes can be completed; and the universality is strong, the mouse brain of the rat and the mouse can be used, in addition, the block trimming is accurate, and the defect of large error of the traditional block trimming is overcome.
Description
Technical Field
The invention relates to the field of brain experiment devices, in particular to a brain block repairing device.
Background
At present, when a brain in-vitro experiment is performed, such as a rat brain in-vitro experiment (more specifically, for example, a rat brain in-vitro brain slice electrophysiological experiment), the rat brain needs to be firstly modified into a special shape required by the experiment; still taking the rat brain as an example, because the bioactivity of the rat brain is reduced in an isolated state, if the time for repairing the block is too long, the activity of a subsequently cut brain slice is reduced and even inactivated, and further the experiment is failed.
The existing brain area block repairing methods are all to repair blocks manually by using a blade, the method is time-consuming, labor-consuming and low in efficiency, and the method is based on different people and has great difference, and particularly, the repaired brain block has large error due to overlong time consumption.
Thus, there is a need for a rapid brain block modification solution.
Disclosure of Invention
Aiming at the defects in the prior art, the invention provides the brain block repairing device, which can rapidly combine the blade and the clamping seat according to the needs by the characteristic of magnetic attraction, rapidly carry out the block repairing operation of the mouse brain, and can accurately complete the block repairing in a very short time; the operation is simple and convenient, the combination is flexible, and the brain block repairing operation of various shapes can be completed; and the universality is strong, the mouse brain of the rat and the mouse can be used, in addition, the block trimming is accurate, and the defect of large error of the traditional block trimming is overcome.
Specifically, the present invention proposes the following specific examples:
the embodiment of the invention provides a brain repair block device, which is applied to a murine brain repair block and comprises the following components: a metal clamping seat and one or more blades; the back of the blade is provided with magnetism, and the back of the blade is connected with the clamping seat through magnetic attraction.
In a specific embodiment, the blade comprises a blade portion and a back portion having magnetic properties; the blade part is connected with the back part.
In a specific embodiment, the back portion is a magnet bar.
In a specific embodiment, the side view cross section of the blade is an isosceles triangle.
In a particular embodiment, the width of the back is greater than the thickness of the tip of the blade.
In a particular embodiment, the length of the back is less than the length of the blade.
In a specific embodiment, the clamping seat is a circular metal plate.
In a specific embodiment, the clamping seat is an iron round plate.
In a specific embodiment, the shape of the cassette is square.
In a specific embodiment, the top end of the clamping seat is further provided with an anti-slip layer.
Therefore, the embodiment of the invention provides a brain repair block device, which is applied to a murine brain repair block and comprises the following components: a metal clamping seat and one or more blades; the back of the blade is provided with magnetism, and the back of the blade is connected with the clamping seat through magnetic attraction. Through the characteristic of magnetic attraction, the blade and the clamping seat can be quickly combined as required, the mouse brain block repairing operation can be quickly carried out, and the block repairing can be accurately finished in a very short time; the operation is simple and convenient, the combination is flexible, and the brain block repairing operation of various shapes can be completed; and the universality is strong, the mouse brain of the rat and the mouse can be used, in addition, the block trimming is accurate, and the defect of large error of the traditional block trimming is overcome.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings needed to be used in the embodiments will be briefly described below, it should be understood that the following drawings only illustrate some embodiments of the present invention and therefore should not be considered as limiting the scope, and for those skilled in the art, other related drawings can be obtained according to the drawings without inventive efforts.
Fig. 1 is a schematic structural diagram of a brain bone repair device according to an embodiment of the present invention;
fig. 2 is a front view of a brain modification apparatus according to an embodiment of the present invention;
fig. 3 is a top view of a brain modification device in accordance with an embodiment of the present invention;
fig. 4 is a side view of a brain modification apparatus in accordance with an embodiment of the present invention;
fig. 5 is a front view of a clamping seat in the brain trimming device according to the embodiment of the present invention;
fig. 6 is a top view of a clamping seat in the brain block repairing device according to the embodiment of the present invention;
fig. 7 is a front view of a clamping seat in the brain trimming device according to the embodiment of the present invention;
fig. 8 is a schematic diagram of a brain block repair requirement proposed by an embodiment of the present invention;
fig. 9 is a schematic diagram of a brain block modification performed by the brain block modification apparatus according to the embodiment of the present invention.
Illustration of the drawings:
1-a card seat;
2-a blade;
21-a blade part; 22-back.
Detailed Description
Various embodiments of the present disclosure will be described more fully hereinafter. The present disclosure is capable of various embodiments and of modifications and variations therein. However, it should be understood that: there is no intention to limit the various embodiments of the disclosure to the specific embodiments disclosed herein, but rather, the disclosure is to cover all modifications, equivalents, and/or alternatives falling within the spirit and scope of the various embodiments of the disclosure.
The terminology used in the various embodiments of the present disclosure is for the purpose of describing particular embodiments only and is not intended to be limiting of the various embodiments of the present disclosure. As used herein, the singular forms are intended to include the plural forms as well, unless the context clearly indicates otherwise. Unless otherwise defined, all terms (including technical and scientific terms) used herein have the same meaning as commonly understood by one of ordinary skill in the art to which the various embodiments of the present disclosure belong. The terms (such as those defined in commonly used dictionaries) should be interpreted as having a meaning that is consistent with their contextual meaning in the relevant art and will not be interpreted in an idealized or overly formal sense unless expressly so defined in various embodiments of the present disclosure.
Examples
The embodiment of the invention discloses a brain repair block device, which is applied to a murine brain repair block and comprises the following components in percentage by weight as shown in the figure: the cutting tool comprises a clamping seat 1 made of metal and one or more blades 2; the back 22 of the blade 2 has magnetism, and the back 22 of the blade 2 is connected with the clamping seat 1 through magnetic attraction.
Specifically, through the device that this scheme provided to cassette 1 is the carrier, according to the repair piece needs of brain, selects one or more blade 2, arranges the shape that 2 cases of blade repair piece needs correspond, and fixes the back 22 of each blade 2 of selecting on cassette 1 with the mode of magnetism absorption, thereby forms one and satisfies the repair piece device that current brain repair piece needs, when specifically using, only need press cassette 1 can once only repair the piece to the brain.
According to the scheme, the blade 2 and the clamping seat 1 can be rapidly combined as required through the characteristic of magnetic attraction, so that the mouse brain block repairing operation can be rapidly carried out, and the block repairing can be accurately finished in a very short time; the operation is simple and convenient, the combination is flexible, and the brain block repairing operation of various shapes can be completed; and the universality is strong, the mouse brain of the rat and the mouse can be used, in addition, the block trimming is accurate, and the defect of large error of the traditional block trimming is overcome.
In a specific embodiment, the blade 2 includes a blade portion 21 and a back portion 22 having magnetic properties; the blade 21 is connected to the back 22.
A more detailed structure of the insert 2 can be shown in fig. 2-4, which includes a blade portion 21 and a back portion 22, wherein the blade portion 21 is used for performing a cutting and trimming process, and the back portion 22 is used for connecting the holder 1.
In one particular embodiment, the back 22 is a magnet bar.
A particular backing 22 may be a cuboid, such as shown in fig. 2-4.
In one embodiment, the blades 21 are as sharp as possible and require a greater depth of cut for better and faster dressing and to avoid injury to the brain, and for this purpose the side view cross section of the blades 21 is isosceles triangle.
In a specific embodiment, in order to ensure the temperature connection of the entire insert 2 with the holder 1, the width of the back portion 22 is greater than the thickness of the top end of the edge portion 21. With this, the stable fixed connection of cutting part 21 is in back 22, and back 22 is bigger for cutting part 21, and area of contact is bigger, and the connection cassette 1 is inhaled to magnetism that can be better more stable, and then has also guaranteed the stability of whole blade 2 in the course of the work.
In a specific embodiment, in order to ensure the convenience of assembling the respective blades 2 and avoid the respective interference, the length of the back portion 22 is smaller than the length of the blade portion 21.
In a specific embodiment, as shown in fig. 5-6, the cartridge 1 is a circular metal plate.
In a specific embodiment, in order to better perform magnetic attraction and ensure the stability of connection, the clamping seat 1 is an iron circular plate.
In a specific embodiment, the holder 1 plays a role of supporting and pressing, and is not limited to be circular, but may be in other shapes, as shown in fig. 7, for example, the shape of the holder 1 is square.
In a specific embodiment, for better brain repair, the stability of both hands is required to be ensured when pressing, and for this reason, the top end of the card holder 1 is further provided with an anti-slip layer.
Through the setting of skid resistant course, can effectively the antiskid, guarantee the stability of pressing, and then guarantee to repair the rapid stabilization accuracy of piece.
In a specific embodiment, as shown in fig. 8, when a brain block needs to be repaired, the blade 2 and the holder 1 may be assembled to form the brain block repairing device shown in fig. 9, and then the brain block repairing device is pressed in the direction shown by the arrow, so that the brain block repairing operation can be completed. The whole process is quick and accurate, the operation is very simple and convenient, the combination is very flexible, the block repairing operation in various shapes can be completed, and the device can adapt to various different brains.
Therefore, the embodiment of the invention provides a brain repair block device, which is applied to a murine brain repair block and comprises the following components: the cutting tool comprises a clamping seat 1 made of metal and one or more blades 2; the back 22 of the blade 2 has magnetism, and the back 22 of the blade 2 is connected with the clamping seat 1 through magnetic attraction. Through the characteristic of magnetic attraction, the blade 2 and the clamping seat 1 can be quickly combined as required, so that the mouse brain block repairing operation can be quickly carried out, and the block repairing can be accurately finished in a very short time; the operation is simple and convenient, the combination is flexible, and the brain block repairing operation of various shapes can be completed; and the universality is strong, the mouse brain of the rat and the mouse can be used, in addition, the block trimming is accurate, and the defect of large error of the traditional block trimming is overcome.
Those skilled in the art will appreciate that the figures are merely schematic representations of one preferred implementation scenario and that the blocks or flow diagrams in the figures are not necessarily required to practice the present invention.
Those skilled in the art will appreciate that the modules in the devices in the implementation scenario may be distributed in the devices in the implementation scenario according to the description of the implementation scenario, or may be located in one or more devices different from the present implementation scenario with corresponding changes. The modules of the implementation scenario may be combined into one module, or may be further split into a plurality of sub-modules.
The above-mentioned invention numbers are merely for description and do not represent the merits of the implementation scenarios.
The above disclosure is only a few specific implementation scenarios of the present invention, however, the present invention is not limited thereto, and any variations that can be made by those skilled in the art are intended to fall within the scope of the present invention.
Claims (7)
1. Brain repair piece device, its characterized in that is applied to the repair piece of murine brain, includes: a metal clamping seat and one or more blades; the back of the blade is magnetic, and the back of the blade is connected with the clamping seat through magnetic attraction;
the blade comprises a blade part and a magnetic back part; the blade part is connected with the back part;
the side view section of the blade part is an isosceles triangle;
the width of the back is larger than the thickness of the top end of the blade part.
2. The brain modification apparatus of claim 1, wherein the back portion is a magnet strip.
3. The brain trimming device of claim 1, wherein the length of the back portion is less than the length of the blade portion.
4. The brain trimming device of claim 1, wherein the cartridge is a circular metal plate.
5. The brain trimming device of claim 1, wherein the cartridge is an iron circular plate.
6. The brain modification apparatus of claim 1, wherein the cartridge is square in shape.
7. The brain trimming device of claim 1, wherein the top end of the clamping base is further provided with an anti-slip layer.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201911127473.7A CN112816275B (en) | 2019-11-18 | 2019-11-18 | Brain repair device |
| PCT/CN2020/129190 WO2021098659A1 (en) | 2019-11-18 | 2020-11-16 | Brain block trimming device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201911127473.7A CN112816275B (en) | 2019-11-18 | 2019-11-18 | Brain repair device |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN112816275A CN112816275A (en) | 2021-05-18 |
| CN112816275B true CN112816275B (en) | 2022-04-05 |
Family
ID=75852410
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201911127473.7A Active CN112816275B (en) | 2019-11-18 | 2019-11-18 | Brain repair device |
Country Status (2)
| Country | Link |
|---|---|
| CN (1) | CN112816275B (en) |
| WO (1) | WO2021098659A1 (en) |
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| US20130037501A1 (en) * | 2011-08-12 | 2013-02-14 | Jordan Michael Schmidt | Multi-sided knife stand assembly |
| CN203077305U (en) * | 2013-02-28 | 2013-07-24 | 西尔扎提·买买提 | Push-type fruit slicer |
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| CN208697601U (en) * | 2018-08-06 | 2019-04-05 | 江苏博之高新材料科技有限公司 | A kind of quick-replaceable banding machine cuts the attachment device of blade |
-
2019
- 2019-11-18 CN CN201911127473.7A patent/CN112816275B/en active Active
-
2020
- 2020-11-16 WO PCT/CN2020/129190 patent/WO2021098659A1/en active Application Filing
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5228160A (en) * | 1992-04-06 | 1993-07-20 | Joseph Porper | Cue tip shaping tool and file fabrication method for use therewith |
| CN102636370A (en) * | 2012-04-27 | 2012-08-15 | 西安交通大学医学院第一附属医院 | Device used for rat brain tissue slicing and layering |
| CN204893996U (en) * | 2015-09-10 | 2015-12-23 | 潘万华 | Branches such as lemon section ware |
| CN108721668A (en) * | 2017-04-14 | 2018-11-02 | 李思模 | A kind of medical operation blade placement magnetic adsorbent equipment |
| CN207336106U (en) * | 2017-08-28 | 2018-05-08 | 山东欣博药物研究有限公司 | Rat cerebral tissue's positioning, which is repaiied, takes device |
| CN208243602U (en) * | 2017-12-07 | 2018-12-18 | 刁荣辉 | A kind of novel magnetic Multifunctional bistoury |
| CN208468542U (en) * | 2018-06-25 | 2019-02-05 | 大连医科大学 | A kind of whole br ain slices block form knife rest |
| CN208902443U (en) * | 2018-09-07 | 2019-05-24 | 广西医科大学第一附属医院 | Rat brain slice tool |
Also Published As
| Publication number | Publication date |
|---|---|
| CN112816275A (en) | 2021-05-18 |
| WO2021098659A1 (en) | 2021-05-27 |
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