CN112790900A - Assembly type medical titanium mesh based on 3d printing technology and manufacturing method thereof - Google Patents
Assembly type medical titanium mesh based on 3d printing technology and manufacturing method thereof Download PDFInfo
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- CN112790900A CN112790900A CN202110128465.5A CN202110128465A CN112790900A CN 112790900 A CN112790900 A CN 112790900A CN 202110128465 A CN202110128465 A CN 202110128465A CN 112790900 A CN112790900 A CN 112790900A
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- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 title claims abstract description 103
- 238000007639 printing Methods 0.000 title claims abstract description 35
- 238000005516 engineering process Methods 0.000 title claims abstract description 21
- 238000004519 manufacturing process Methods 0.000 title claims description 25
- 229910052719 titanium Inorganic materials 0.000 claims abstract description 33
- 239000010936 titanium Substances 0.000 claims abstract description 33
- 210000000988 bone and bone Anatomy 0.000 claims abstract description 29
- 238000000034 method Methods 0.000 claims description 11
- 239000011247 coating layer Substances 0.000 claims description 8
- 230000007246 mechanism Effects 0.000 claims description 6
- 238000010146 3D printing Methods 0.000 claims description 4
- 229910052588 hydroxylapatite Inorganic materials 0.000 claims description 3
- XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical group [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 claims description 3
- 230000004927 fusion Effects 0.000 abstract description 16
- 238000010883 osseointegration Methods 0.000 abstract description 6
- 239000011148 porous material Substances 0.000 abstract description 2
- 238000004458 analytical method Methods 0.000 description 4
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Images
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
- A61F2/4455—Joints for the spine, e.g. vertebrae, spinal discs for the fusion of spinal bodies, e.g. intervertebral fusion of adjacent spinal bodies, e.g. fusion cages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
- A61F2/30907—Nets or sleeves applied to surface of prostheses or in cement
- A61F2002/30909—Nets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/3094—Designing or manufacturing processes
- A61F2002/30985—Designing or manufacturing processes using three dimensional printing [3DP]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
- A61F2002/4495—Joints for the spine, e.g. vertebrae, spinal discs having a fabric structure, e.g. made from wires or fibres
Abstract
The invention discloses a matched medical titanium net based on a 3d printing technology, which comprises two columnar titanium nets and end plates, wherein the two end plates are respectively connected to two ends of the columnar titanium net, the end plates are detachably connected with the columnar titanium nets, the end plates are manufactured by 3d printing, and bone grafting holes are formed in the end plates. The invention solves the problem that the existing titanium mesh can not be well matched with the personalized vertebral end plate of a patient, the contact area is increased, and the end plate is not easy to be punctured to cause complications such as titanium mesh sinking and the like; meanwhile, the stability of the titanium mesh is increased due to good matching. The annular bone grafting component and the porous material osseointegration are integrated with the traditional bone grafting cavity osseointegration, so that a fusion double-insurance mode is realized; the bone fusion distance spanning 1 vertebral body or a plurality of vertebral bodies is converted into the fusion of the residual vertebral bodies and the intervertebral space of the lower or upper vertebral body, so that the fusion efficiency is improved, and the risk of non-fusion and titanium mesh sinking is reduced.
Description
Technical Field
The invention relates to the field of medical instruments, in particular to a matched stack type medical titanium mesh based on a 3d printing technology.
Background
Cervical spondylotomy (ACCF) is suitable for patients who can not obtain good spinal decompression after simple discectomy, and can be used for combined posterior spinal canal enlargement based on ACCF for patients who have both anterior and posterior spinal compression. The ACCF is also an ideal choice for patients with vertebral body lesions (tumors, etc.), cervical dislocation and kyphotic deformity.
The existing ACCF surgical titanium mesh has the following defects:
1. after the existing straight titanium net is placed on the cervical vertebra, because the cervical vertebra of a human body has a certain physiological radian and is not straight, two ends of the titanium net can not be in good contact with a patient end plate, only one part of the titanium net is in direct contact with a vertebral end plate, and in addition, the titanium net sinks after operation, the radian loss of the cervical vertebra of the patient can be further aggravated, and the radian of the cervical vertebra can not be well reconstructed and maintained.
2. The risk complication of the displacement and sinking of the titanium mesh after the operation of the patient is high; the titanium mesh is not fixed and is easy to shift into the vertebral canal, so that the paralysis and even death of the patient are caused; the incidence rate of postoperative titanium mesh subsidence can reach 70 percent.
3. The crossing distance after the vertebral body is removed in the ACCF operation is longer, and the creeping substitution distance of bones is longer, so that the fusion time is longer, the fusion efficiency is lower, and the re-operation revision risk is higher; the bone grafting has poor healing effect and long time, so that a lot of patients still do not heal in 6 months and 12 months, and need to wear the external cervical fixation branch for a long time, which is not beneficial to the early rehabilitation of the patients and the return to normal life and work;
4. the concept of high quality prosthesis-endplate interface osseointegration mainly includes the following aspects: (1) under functional loading, the bone tissue has enough support to the endophyte; (2) the shape of the new bone tissue is consistent with the shape of the surface of the implant and is closely contacted with the surface of the implant, and the interface of the implant and the bone tissue has no connective tissue or fibrous tissue interval; (3) under functional loading, there is no relative motion between the endoprosthesis and the surrounding tissue; (4) under the optical and electron microscope, the tissue components in the thin layer of the surface of the inner implant should be normal bone tissue components. The existing titanium mesh can not perform good osseointegration with vertebral end plates, and is not beneficial to improving the stability and increasing the fusion rate.
In conclusion, how to promote the ACCF surgical fusion spanning the length of a vertebral body or even a plurality of vertebral bodies, increase the matching property of the titanium mesh and the vertebral body end plate, recover and maintain the radian of the cervical vertebra, reduce the risks of sinking and shifting of the post-operation titanium mesh, improve the operation safety, improve the fusion rate, shorten the fusion time, reduce the work delay time and promote the early rehabilitation is a problem faced by the plants in the ACCF surgical titanium mesh at the present stage.
Disclosure of Invention
The human intervertebral space endplate forms have certain personalized characteristics, and the inventor analyzes the CT data of 510 segments of 85 non-cervical spondylosis patients C2-7 and discovers the following results after the analysis and measurement are carried out by using image three-dimensional reconstruction software Mimics 15: the coronary surface of the cervical vertebra lower end plate can be divided into three types, namely an arc shape, a flat plate shape and an irregular shape. The two ends of the plant in the existing medical titanium mesh are relatively sharp, and the plant is not designed and manufactured individually and cannot be well matched with the vertebral bone end plate of a patient. The contact area of the titanium mesh and the bony end plate is reduced when the medical titanium mesh can not be well matched, and the sinking complication of the titanium mesh after operation is increased, which is not beneficial to the recovery of patients, so the medical titanium mesh needs to be further improved and designed, and the matching property of the shape of the end plate is increased.
In order to achieve the purpose, the invention is realized by adopting the following technical scheme:
the invention discloses a matched medical titanium net based on a 3d printing technology, which comprises two columnar titanium nets and end plates, wherein the two end plates are respectively connected to two ends of the columnar titanium net, the end plates are detachably connected with the columnar titanium nets, the end plates are manufactured by 3d printing, and bone grafting holes are formed in the end plates.
Preferably, the columnar titanium mesh comprises a front piece and a rear piece, the front piece comprises a left front piece and a right front piece, the adjacent edges of the left front piece and the right front piece are lapped and provided with a clamping mechanism, and the other edges of the left front piece and the right front piece are respectively in toothed connection with the rear piece.
Preferably, the number of the bone grafting holes on the end plate is at least 3, wherein one bone grafting hole is positioned in the center of the end plate and is communicated with the inner cavity of the columnar titanium mesh, and the other two bone grafting holes are respectively positioned on the opposite sides of the columnar titanium mesh.
Preferably, the detachable connection is a bolt connection or a buckle connection, an included angle between the end plate and the columnar titanium net is adjustable, and a fit clearance exists in the detachable connection.
Further preferably, the bolted connection comprises a groove on the end plate, and the end of the columnar titanium mesh is inserted into the groove and is mounted in the groove by an elastic bolt.
Furthermore, the surface of the end plate, which is far away from the columnar titanium net, is provided with sharp thorns.
Further, a coating layer covers the surface, far away from the columnar titanium mesh, of the end plate, and the coating layer is of a porous structure; the coating layer is preferably hydroxyapatite.
Preferably, the end plate comprises an upper end plate and a lower end plate, the upper surface of the upper end plate is attached to the lower end face of the upper vertebral body of the patient, and the lower surface of the lower end plate is attached to the upper end face of the lower vertebral body of the patient.
The invention also discloses a manufacturing method of the assembled medical titanium mesh based on the 3d printing technology, which comprises a manufacturing method of the end plate, wherein the manufacturing method of the end plate comprises the following steps:
a1, correcting original DICOM format data of cervical vertebra CT three-dimensional scanning before operation of a patient;
a2, extracting parameters of the upper and lower bony endplates of the intervertebral space of the simulated operation segment;
a3, and creating data for 3D printing, and sending the data to a 3D printer for printing.
The invention also discloses another manufacturing method of the assembled medical titanium mesh based on the 3d printing technology, which comprises a manufacturing method of the end plate, wherein the manufacturing method of the end plate comprises the following steps: and analyzing the measured parameters of the upper and lower bony end plates in the intervertebral space through big data, classifying the surface forms of the upper and lower bony end plates in the intervertebral space, and manufacturing the end plates which are attached with the classification through 3d printing.
The invention has the following beneficial effects:
1. the invention solves the problem that the existing titanium mesh can not be well matched with the personalized vertebral end plate of a patient, the contact area is increased, and the end plate is not easy to be punctured to cause complications such as titanium mesh sinking and the like; meanwhile, the stability of the titanium mesh is increased due to good matching.
2. The annular bone grafting component and the porous material osseointegration are integrated with the traditional bone grafting cavity osseointegration, so that a fusion double-insurance mode is realized; the bone fusion distance spanning 1 vertebral body or a plurality of vertebral bodies is converted into the fusion of the residual vertebral bodies and the intervertebral space of the lower or upper vertebral body, so that the fusion efficiency is improved, and the risk of non-fusion and titanium mesh sinking is reduced.
3. Postoperative patient need not wear external fixation such as neck brace for a long time, can earlier return normal work and life, and is less to patient psychological influence, is favorable to reducing health economic burden.
4. The invention increases the stability and the safety, reduces the risks of the ACCF operation titanium mesh sinking, shifting and protruding into the vertebral canal to injure the spinal cord, and reduces the operation related complications;
5. the invention is assembled, can adjust the height and the angle, is convenient to adjust the included angle of the end plates of different patients, increases the stability and reduces the sinking risk after operation. The height can be adjusted after the implantation, thereby facilitating the further distraction operation.
6. The 3d printing technology is combined with the traditional processing technology, and the assembly type production is realized, so that the production efficiency is improved, and the large-scale development and popularization are facilitated.
Drawings
FIG. 1 is a schematic view of the structure of the present invention.
Fig. 2 is a partial schematic view of the connection of the columnar titanium mesh and the end plate.
FIG. 3 is a schematic structural diagram of a columnar titanium mesh.
Fig. 4 is a first usage diagram of the present invention.
FIG. 5 is a second schematic diagram of the present invention.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is further described in detail below with reference to the accompanying drawings.
As shown in figure 1, the invention discloses a matched stack type medical titanium mesh based on a 3d printing technology, which comprises a columnar titanium mesh 1 and two end plates 2, wherein the two end plates 2 are respectively connected with two ends of the columnar titanium mesh 1, the end plates 2 are detachably connected with the columnar titanium mesh 1, the end plates 2 are manufactured by 3d printing, bone grafting holes 21 are arranged on the end plates 2, at least 3 bone grafting holes 21 are arranged on the same end plate 2, one of the bone grafting holes 21 is positioned in the center of the end plate 2 and is communicated with an inner cavity of the columnar titanium mesh 1, and the other two bone grafting holes 21 are respectively positioned on the opposite sides of the columnar titanium mesh 1.
The surface of the end plate 2 away from the columnar titanium mesh 1 is provided with sharp spines 22, or the surface of the end plate 2 away from the columnar titanium mesh 1 can be covered with a coating layer which is of a porous structure; the coating layer is preferably hydroxyapatite; the spikes 22 and the coating may also be present simultaneously.
The detachable connection is a bolt connection or a snap connection, and the detachable connection has a fit clearance, specifically, as shown in fig. 2, the bolt connection includes a groove 23 on the end plate 2, and the end of the columnar titanium mesh 1 is inserted into the groove 23 and is installed in the groove 23 through the elastic bolt 3.
The included angle between the end plate 2 and the columnar titanium net 1 is adjustable, specifically, as shown in fig. 3, the columnar titanium net 1 comprises a front piece 11 and a rear piece 12, the front piece 11 comprises a left front piece and a right front piece, the adjacent edges of the left front piece and the right front piece are lapped and provided with a clamping mechanism, the other edges of the left front piece and the right front piece are respectively in gear connection with the rear piece, and the gear connection comprises a gear adjusting mechanism 13. The height difference of the front sheet 11 and the back sheet 12 and the included angle between the columnar titanium mesh 1 and the end plate 2 can be adjusted through the gear adjusting mechanism 13.
As shown in fig. 4 and 5, the end plate 2 includes an upper end plate and a lower end plate, and when in use, the upper surface of the upper end plate is fitted to the lower end surface of the upper vertebral body 5 of the patient, and the lower surface of the lower end plate is fitted to the upper end surface of the lower vertebral body 6 of the patient. The columnar titanium net 1 and the residual vertebral bodies 4 on the two sides can be fixed by adopting two mounting screws 7, the left front piece and the right front piece are arranged, the mounting of the mounting screws 7 is convenient, and after the mounting screws 7 are mounted, the left front piece and the right front piece are firmly clamped by a clamping mechanism.
The invention discloses a manufacturing method of an assembled medical titanium mesh based on a 3d printing technology, wherein the manufacturing method of an end plate comprises a personalized customization method and a classified manufacturing method.
The personalized customization method comprises the following steps:
a1, correcting original DICOM format data of cervical vertebra CT three-dimensional scanning before operation of a patient;
a2, extracting parameters of the upper and lower bony endplates of the intervertebral space of the simulated operation segment;
a3, and creating data for 3D printing, and sending the data to a 3D printer for printing.
The individual customization can ensure the optimal fit of the end plates with the upper and lower vertebral bodies.
The classified manufacturing method comprises the following steps: and (3) analyzing the measured parameters of the upper and lower bony end plates in the intervertebral space through big data, classifying the surface forms of the upper and lower bony end plates in the intervertebral space, and printing and manufacturing the end plates which are attached in a classified mode through 3 d.
The classified manufacture provides end plates with various specifications, and when the end plates are used, the end plates closest to the upper and lower vertebral bodies of a patient can be selected, so that the fitting degree of the end plates and the upper and lower vertebral bodies is ensured as much as possible.
The specific implementation of the personalized customization method and the classification manufacturing method is as follows:
firstly, acquiring image data
The main data come from CT, MRI, three-dimensional ultrasound and the like, the imaging device acquires the imaging tomography images consistent with the real state of the human body, the imaging tomography images are transmitted and stored in a DICOM format, the data are used for establishing a three-dimensional model of the human body structure, the three-dimensional model is stored in an STL format, and the three-dimensional model is identified and printed by a 3D printer.
Two, 3D print data extraction and rapid modeling system
1. Analysis of design theory
In order to realize the purpose of automatic and rapid modeling, the whole process is decomposed into the following main steps according to the actual operation flow:
generating a basic model based on image data;
calculating and generating titanium mesh data by taking the geometric form as a reference;
processing the surface of the titanium mesh;
creating a solid model of the titanium net;
2. system design development
Data modeling and geometric form reference calculation: the image of the patient needs to be three-dimensional volume data to obtain good three-dimensional reconstruction data, and the three-dimensional geometric information of the appearance of the cervical vertebra is digitized and converted into an STL format;
secondly, surface treatment of the model: polishing the surface to adapt to the internal environment after being implanted into a human body;
3. the titanium mesh solid model is realized: according to different market demands, the method is divided into a personalized customized titanium net and a common titanium net produced according to specifications. A. The personalized titanium mesh is personalized and customized based on the individual cervical vertebra three-dimensional data, is suitable for high-end consumer groups, and has high attaching degree and good operation effect; B. the titanium net produced based on the specification belongs to a titanium net in common, namely interval division is carried out according to cervical vertebra three-dimensional big data samples of Chinese people, the proper size of each individual is selected for use, and the titanium net can be selected and matched before operation and is suitable for middle-end consumer groups.
Three, 3D prints titanium net and is used for anterior cervical vertebra surgical finite element analysis
1. Processing of the original image: and after obtaining the three-dimensional models of the bones and the soft tissues, exporting and storing the three-dimensional models in an STL format file.
2. Three-dimensional solid reconstruction of cervical vertebra: through the functions of stretching, cutting and the like in Solidworks, modeling and assembling are carried out according to an external fixing support drawing to finally obtain a complete geometric model
3. Establishing a cervical vertebra finite element model: and (4) introducing the model into finite element analysis soft workbench18.0, and performing Boolean operation. And cutting by using a software curved surface cutting function.
4. Calculating settings: material property assignments and contact settings.
Implementation process of four-dimensional and 3D printing titanium mesh
1. Printing of titanium mesh
Printing a cylindrical titanium mesh component: the titanium mesh is used as a main body of the novel titanium mesh and plays a role in supporting;
printing 4 ear-shaped annular bone grafting parts of the titanium mesh: as an intervertebral bone graft region;
printing of a rear rotating shaft: can be opened and rotated;
printing by the front opening device: after being screwed down, the spine can be made to pierce into the lateral vertebral body;
printing of lateral spine and front screw: inserting the residual vertebral body for titanium mesh fixation;
2. application of titanium mesh
As mentioned above, the method is divided into A, B scheme applications, and the post-production application comprises:
firstly, grinding a titanium net;
② a matching and fixing device of the titanium mesh, and the like.
The present invention is capable of other embodiments, and various changes and modifications may be made by one skilled in the art without departing from the spirit and scope of the invention.
Claims (10)
1. An assembled medical titanium mesh based on 3d printing technology is characterized in that: including column titanium net and end plate, the end plate has two, and two end plates are connected respectively at the both ends of column titanium net, and the end plate can be dismantled with column titanium net and be connected, and the end plate is 3d and prints the manufacturing, is equipped with on the end plate and plants the bone hole.
2. The assembled medical titanium mesh based on 3d printing technology according to claim 1, wherein: the columnar titanium net comprises a front piece and a rear piece, the front piece comprises a left front piece and a right front piece, the adjacent edges of the left front piece and the right front piece are lapped and provided with a clamping mechanism, and the other edges of the left front piece and the right front piece are respectively in gear connection with the rear piece.
3. The assembled medical titanium mesh based on 3d printing technology according to claim 1, wherein: the number of bone grafting holes on the end plate is at least 3, wherein one bone grafting hole is positioned in the center of the end plate and is communicated with the inner cavity of the columnar titanium net, and the other two bone grafting holes are respectively positioned on the opposite sides of the columnar titanium net.
4. The assembled medical titanium mesh based on 3d printing technology according to claim 1, wherein: the detachable connection is a bolt connection or a buckle connection, an included angle between the end plate and the columnar titanium net is adjustable, and a fit clearance exists in the detachable connection.
5. The assembled medical titanium mesh based on 3d printing technology according to claim 4, wherein: the bolted connection includes the recess that is located the end plate, the tip of column titanium net inserts in the recess to install in the recess through the elastic bolt.
6. The assembled medical titanium mesh based on 3d printing technology according to claim 1, wherein: and the surface of the end plate, which is far away from the columnar titanium mesh, is provided with sharp thorns.
7. The assembled medical titanium mesh based on 3d printing technology according to claim 1, wherein: the surface of the end plate, which is far away from the columnar titanium mesh, is covered with a coating layer, and the coating layer is of a porous structure; the coating layer is preferably hydroxyapatite.
8. The assembled medical titanium mesh based on 3d printing technology according to any one of claims 1 to 7, wherein: the end plate comprises an upper end plate and a lower end plate, the upper surface of the upper end plate is attached to the lower end face of an upper vertebral body of a patient, and the lower surface of the lower end plate is attached to the upper end face of a lower vertebral body of the patient.
9. The method for manufacturing the assembled medical titanium mesh based on the 3d printing technology according to claim 8, wherein the method comprises the following steps: the manufacturing method of the end plate comprises the following steps:
a1, correcting original DICOM format data of cervical vertebra CT three-dimensional scanning before operation of a patient;
a2, extracting parameters of the upper and lower bony endplates of the intervertebral space of the simulated operation segment;
a3, and creating data for 3D printing, and sending the data to a 3D printer for printing.
10. The method for manufacturing the assembled medical titanium mesh based on the 3d printing technology according to any one of claims 1 to 7, wherein the method comprises the following steps: the manufacturing method of the end plate comprises the following steps: and analyzing the measured parameters of the upper and lower bony end plates in the intervertebral space through big data, classifying the surface forms of the upper and lower bony end plates in the intervertebral space, and manufacturing the end plates which are attached with the classification through 3d printing.
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| CN202110128465.5A CN112790900A (en) | 2021-01-29 | 2021-01-29 | Assembly type medical titanium mesh based on 3d printing technology and manufacturing method thereof |
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Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105411727A (en) * | 2015-12-30 | 2016-03-23 | 四川大学华西医院 | Adjustable and interface type zero-incisura titanium mesh supporting, fusing and fixing system for anterior cervical spine |
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