CN112790754A - Intrathoracic pressure measuring device - Google Patents

Intrathoracic pressure measuring device Download PDF

Info

Publication number
CN112790754A
CN112790754A CN202110005877.XA CN202110005877A CN112790754A CN 112790754 A CN112790754 A CN 112790754A CN 202110005877 A CN202110005877 A CN 202110005877A CN 112790754 A CN112790754 A CN 112790754A
Authority
CN
China
Prior art keywords
pressure measurement
time
synchronous
intraoral
measurement data
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN202110005877.XA
Other languages
Chinese (zh)
Other versions
CN112790754B (en
Inventor
刘颖娴
吴炜
徐思驰
宋彦君
孔畅
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Peking Union Medical College Hospital Chinese Academy of Medical Sciences
Original Assignee
Peking Union Medical College Hospital Chinese Academy of Medical Sciences
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Peking Union Medical College Hospital Chinese Academy of Medical Sciences filed Critical Peking Union Medical College Hospital Chinese Academy of Medical Sciences
Priority to CN202110005877.XA priority Critical patent/CN112790754B/en
Publication of CN112790754A publication Critical patent/CN112790754A/en
Priority to PCT/CN2021/094878 priority patent/WO2022147944A1/en
Application granted granted Critical
Publication of CN112790754B publication Critical patent/CN112790754B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/03—Detecting, measuring or recording fluid pressure within the body other than blood pressure, e.g. cerebral pressure; Measuring pressure in body tissues or organs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7203—Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Signal Processing (AREA)
  • Surgery (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Artificial Intelligence (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Physiology (AREA)
  • Psychiatry (AREA)
  • Hematology (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)

Abstract

The invention provides a intrathoracic pressure measuring device, which comprises: the system comprises a processor, a synchronous database and an intraoral pressure measuring device; the synchronous database stores synchronous intrathoracic pressure measurement data and synchronous intraoral pressure measurement data of a measured person; the processor is used for determining the mapping relation between the intrathoracic pressure and the intraoral pressure of the measured person according to the synchronous intrathoracic pressure measurement data and the synchronous intraoral pressure measurement data, and obtaining the corresponding real-time intrathoracic pressure according to the mapping relation and the real-time intraoral pressure of the measured person within the preset time period measured by the intraoral pressure measurement device. The invention can improve the comfort level and the measurement accuracy of the user.

Description

Intrathoracic pressure measuring device
Technical Field
The invention relates to the field of intrathoracic pressure measurement, in particular to a intrathoracic pressure measurement device.
Background
For people with difficulty in breathing, real-time monitoring of intrathoracic pressure is essential. The commonly used intrathoracic pressure measurement method mainly comprises the following steps:
the direct method comprises the following steps: the injection needle connected with the pressure detector is obliquely penetrated into the pleural cavity, and the pressure in the pleural cavity can be directly indicated by the liquid of the pressure detector. The direct method has the disadvantage of risking puncturing the pleural layer and lungs and the subject feels uncomfortable.
An indirect method: the subject swallows a catheter with a thin-walled balloon to the esophagus of the lower chest, and changes in intra-esophageal pressure during respiration are measured to indirectly indicate changes in intra-pleural pressure. This is because the esophagus is located between the lung and the chest wall in the chest, and the esophageal wall is thin and soft, and the values of the two changes are substantially the same during breathing. Therefore, the change of the pressure in the esophagus can be measured to indirectly reflect the change of the pressure in the pleural cavity. Indirect methods reduce the risk of puncturing the pleural layers and lungs compared to direct methods, but are still uncomfortable for the person being measured due to the need to swallow a catheter with a thin-walled balloon into the esophagus of the lower chest.
Further, patent document 1(CN107613865A) provides a chest pressure calculation device and a chest pressure calculation method in which a relationship between the chest pressure and the oral pressure is derived by simulation, and the corresponding chest pressure is obtained by measuring the oral pressure based on the relationship. The scheme has the advantages of no wound, little damage to a measured person and no discomfort, and has the defect that the relation between the intrathoracic pressure and the oral pressure obtained through simulation is inaccurate.
Therefore, there is a need to provide a solution that enables non-invasive and accurate measurement of intrathoracic pressure.
Disclosure of Invention
The embodiment of the invention provides a intrathoracic pressure measuring device which can obtain accurate intrathoracic pressure noninvasively and has accurate measurement and high comfort level.
The technical scheme adopted by the invention is as follows:
the embodiment of the invention provides a intrathoracic pressure measuring device, which comprises: the system comprises a processor, a synchronous database and an intraoral pressure measuring device; the synchronous database stores synchronous intrathoracic pressure measurement data B ═ B (B) of the measured person1，B2，......，Bm) And synchronous intraoral pressure measurement data M ═ (M1, M)2，......Mm) Said synchronized intrathoracic pressure measurement dataAnd the synchronous intraoral pressure measurement data is obtained by invasive measurement of the intrathoracic pressure of the subject and intraoral pressure measurement is carried out simultaneously, wherein BiAnd MiRespectively obtaining a synchronous intrathoracic pressure value and an intraoral pressure value sampled and obtained at the ith preset time dt, wherein the value of i is 1.. m;
the processor is used for determining the mapping relation between the intrathoracic pressure and the intraoral pressure of the measured person according to the synchronous intrathoracic pressure measurement data and the synchronous intraoral pressure measurement data, and obtaining the corresponding real-time intrathoracic pressure according to the mapping relation and the real-time intraoral pressure of the measured person within the preset time period measured by the intraoral pressure measurement device; the mapping relation between the intrathoracic pressure and the intra-oral pressure is as follows: b ═ α × M + β, α and β are coefficients of the mapping relationships, respectively.
Optionally, the determining a mapping relationship between the intrathoracic pressure and the intraoral pressure of the subject according to the synchronized intrathoracic pressure measurement data and the synchronized intraoral pressure measurement data includes the following steps:
s100, denoising the synchronous intrathoracic pressure measurement data B and the synchronous intraoral pressure measurement data M to obtain denoised synchronous intrathoracic pressure measurement data B 'and synchronous intraoral pressure measurement data M';
s200, determining alpha and beta by adopting a least square method according to the synchronous intrathoracic pressure measurement data B 'and the synchronous intraoral pressure measurement data M' which are subjected to denoising treatment;
and S300, storing the alpha and the beta.
Optionally, S100 further comprises:
s110, obtaining difference data dB (dB) of synchronous intrathoracic pressure measurement data B1，dB2，...，dBm-1) Difference data dM ═ dM of the synchronous intraoral pressure measurement data M1，dM2，...，dMm-1) Wherein, dBj＝Bj+1-Bj，dMj＝Mj+1-MjJ has a value of 1. (m-1);
s120, if dBj-dMjIf it is greater than the preset threshold, then B will bej+1And Mj+1And removing noise points to obtain synchronous intrathoracic pressure measurement data B 'and synchronous intraoral pressure measurement data M' after noise removal.
Optionally, S100 further comprises:
s130, obtaining difference data dB (dB) of synchronous intrathoracic pressure measurement data B1，dB2，...，dBm-1) Difference data dM ═ dM of the synchronous intraoral pressure measurement data M1，dM2，...，dMm-1) Wherein, dBj＝Bj+1-Bj，dMj＝Mj+1-MjJ has a value of 1. (m-1);
s140, if Bi+1≥BiIf the value of dBi is equal to the first identifier, otherwise, dBi is equal to the second identifier; and if Mi+1≥MiThen dMi is the first identifier, otherwise dMi is the second identifier; the first identifier and the second identifier are different;
s150, if dBiNot equal to dMiThen B will bei+1And Mi+1As the noise point removal, B 'and M' after noise removal are obtained.
Optionally, the determining a mapping relationship between the intrathoracic pressure and the intraoral pressure of the subject according to the synchronized intrathoracic pressure measurement data and the synchronized intraoral pressure measurement data includes:
a is based on
Figure BDA0002883168890000031
Determining;
said beta is based on
Figure BDA0002883168890000032
Determining;
wherein, dBj＝Bj+1-Bj，dMj＝Mj+1-Mj。
Optionally, the obtaining a corresponding real-time intrathoracic pressure according to the mapping relationship and the real-time intraoral pressure of the measured person within the preset time period measured by the intraoral pressure measuring device includes:
s10, acquiring an oral pressure measurement value M0 measured by an oral pressure measurement device in real time;
s20, obtaining a corresponding real-time intrathoracic pressure measured value B0 ═ α × M0+ β according to the α and the β;
and S30, displaying the real-time intrathoracic pressure measurement value B0.
Optionally, the processor is further configured to:
displaying an M curve of the synchronous intraoral pressure measurement data M and an M0 curve of intraoral pressure measurement value M0 obtained in real time along with time on the mobile terminal of the measured person; and
comparing the intraoral pressure data acquired in real time with the synchronized intraoral pressure measurement data based on the M curve and the M0 curve.
Optionally, comparing the intraoral pressure data acquired in real time with the synchronous intraoral pressure measurement data based on the M curve and the M0 curve, including:
receiving one or more time pairs (S) on the M curve and the M0 curve specified by the userk，Ek) K is 1, or>1，SkThe expression is the start time, EkRepresents an end time;
displaying a corresponding M-M0 curve on the mobile terminal based on the time-pairs.
Optionally, the receiving user-specified M-curve and one or more time pairs on the M0 curve (S)k，Ek) The method comprises the following steps:
receiving the starting time S specified by the user on the M0 curvekThen the start time SkDragging the corresponding point to the corresponding point on the M curve;
receiving the end time E specified by the user on the M0 curvekThen according to the start time SkAnd end time EkAutomatically marks the corresponding reception time E on the M-curvekWherein, in the M curve, the time E is endedkCoordinates on the time axis are start times SkThe sum of the time axis coordinate and the time span.
Optionally, the displaying a corresponding M-M0 curve on the mobile terminal based on the time pair includes:
time pair (S)k，Ek) The M curve in between and the M0 curve translate to the M-M0 curve.
According to the intrathoracic pressure measuring device provided by the embodiment of the invention, the mapping relation between intrathoracic pressure and intraoral pressure is determined by the intrathoracic pressure measurement data of invasive measurement and the intraoral pressure measurement data of intraoral pressure measurement which are synchronously carried out, so that the mapping relation is accurate. When the intrathoracic pressure needs to be measured, according to the determined mapping relation, the user can directly obtain the corresponding intrathoracic pressure at home through measuring the intraoral pressure, the time for the user to go to a hospital for measurement can be reduced, discomfort caused by invasive measurement can be avoided, and the method is simple, convenient and accurate and has good user experience.
Drawings
Fig. 1 is a schematic structural diagram of an intrathoracic pressure measurement device according to an embodiment of the present invention;
FIG. 2 is a schematic illustration of an intraoral pressure curve displayed on a user's mobile terminal;
fig. 3 is a schematic diagram for automatically presenting the peak value and the valley value of the intra-oral pressure curve on the mobile terminal of the user.
Detailed Description
In order to make the technical problems, technical solutions and advantages of the present invention more apparent, the following detailed description is given with reference to the accompanying drawings and specific embodiments.
In some of the flows described in the present specification and claims and in the above figures, a number of operations are included that occur in a particular order, but it should be clearly understood that these operations may be performed out of order or in parallel as they occur herein, with the order of the operations being indicated as 101, 102, etc. merely to distinguish between the various operations, and the order of the operations by themselves does not represent any order of performance. Additionally, the flows may include more or fewer operations, and the operations may be performed sequentially or in parallel.
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Fig. 1 is a schematic structural diagram of a intrathoracic pressure measurement device according to an embodiment of the present invention. As shown in fig. 1, an embodiment of the present invention provides an intrathoracic pressure measurement device, including: a processor 1, a synchronization database 2 and an intraoral pressure measuring device 3.
In the embodiment of the present invention, the intraoral pressure measuring device 3 may be, for example, an intraoral pressure measuring device used in patent document 1, or another intraoral pressure measuring device in the related art, which is used to acquire the intraoral pressure of the subject to be measured.
The synchronous database 2 stores synchronous intrathoracic pressure measurement data B ═ (B) of the subject to be measured1，B2，......，Bm) And synchronous intraoral pressure measurement data M ═ (M1, M)2，......Mm) And the synchronous intrathoracic pressure measurement data and the synchronous intraoral pressure measurement data are obtained by simultaneously measuring intraoral pressure of the subject when the subject is subjected to invasive intrathoracic pressure measurement, wherein BiAnd MiThe synchronous intrathoracic pressure value and the intraoral pressure value sampled and obtained at the ith preset time dt are respectively, and the value of i is 1. In an exemplary embodiment, the preset time dt is set to a time that completely describes a waveform of a respiratory cycle, e.g., an average of 3 seconds for an adult to complete a breath, and the preset time dt may be set to, e.g., 0.1-0.3 seconds, such that 10-30 points of a breath will be sampled.
The processor 1 executes a computer program for determining a mapping relationship between the intrathoracic pressure and the intraoral pressure of the measured person according to the synchronous intrathoracic pressure measurement data and the synchronous intraoral pressure measurement data, and obtaining a corresponding real-time intrathoracic pressure according to the mapping relationship and the real-time intraoral pressure of the measured person within a preset time period measured by the intraoral pressure measurement device. In the embodiment of the present invention, the processor 1 may be disposed in the cloud, or may be disposed locally, for example, on a mobile terminal of a measured person.
In an embodiment of the present invention, the mapping relationship between the intrathoracic pressure and the intraoral pressure is a linear relationship, and specifically, the mapping relationship may be: b ═ α × M + β, α and β are coefficients of the mapping relationships, respectively.
Further, in one embodiment, a and β may be determined using a least squares method based on the synchronized intrathoracic pressure measurement data B and the synchronized intraoral pressure measurement data M. How to determine the alpha sum by using the least square method is the prior art, and the detailed description thereof is omitted in the present invention for avoiding redundancy. The determined coefficients and β may be stored in non-volatile registers. The register may be a component of the intrathoracic pressure measurement device.
Further, in another embodiment, the synchronous intrathoracic pressure measurement data B and the synchronous intraoral pressure measurement data M may be subjected to fast de-noising detection, and then α and β may be determined by using the least square method. The accuracy of the coefficients alpha and beta can be improved by eliminating the noise caused by the equipment of the intrathoracic pressure measuring device and the intraoral pressure measuring device, in particular the burr noise of the equipment. In particular, the processor 1 executes a computer program implementing the steps of:
s100, denoising the synchronous intrathoracic pressure measurement data B and the synchronous intraoral pressure measurement data M to obtain denoised synchronous intrathoracic pressure measurement data B 'and synchronous intraoral pressure measurement data M'.
S200, determining alpha and beta by adopting a least square method according to the synchronous intrathoracic pressure measurement data B 'and the synchronous intraoral pressure measurement data M' after denoising treatment.
And S300, storing the alpha and the beta.
In an exemplary embodiment, S100 further includes:
s110, obtaining difference data dB (dB) of synchronous intrathoracic pressure measurement data B1，dB2，...，dBm-1) Difference data dM ═ dM of the synchronous intraoral pressure measurement data M1，dM2，...，dMm-1) Wherein, dBj＝Bj+1-Bj，dMj＝Mj+1-MjJ has a value of 1. (m-1).
S120, if dBj-dMj is larger than the preset threshold value, B is addedj+1And Mj+1As the noise point removal, B 'and M' after noise removal are obtained. The preset threshold may be an empirical value, and the present invention is not particularly limited.
In another exemplary embodiment, S100 may further include:
s130, obtaining difference data dB (dB) of synchronous intrathoracic pressure measurement data B1，dB2，...，dBm-1) Difference data dM ═ dM of the synchronous intraoral pressure measurement data M1，dM2，...，dMm-1) Wherein, dBj＝Bj+1-Bj，dMj＝Mj+1-MjJ has a value of 1. (m-1).
S140, if Bi+1≥BiIf the value of dBi is equal to the first identifier, otherwise, dBi is equal to the second identifier; and
if M isi+1≥MiThen dMi is the first identifier, otherwise dMi is the second identifier; the first identifier and the second identifier are different. In one exemplary embodiment, the first flag may be set to 1 and the second flag may be set to 0.
S150, if dBiNot equal to dMiThen B will bei+1And Mi+1As the noise point removal, B 'and M' after noise removal are obtained.
Compared with the processing modes of steps S110 to S120, steps S130 to S150 can remove noise points in the synchronous intrathoracic pressure measurement data B and the synchronous intraoral pressure measurement data M more quickly, and for the processor disposed in the cloud, the processing speed can be increased, and resources can be saved.
The sum determined in step S200 using the least squares method may be prior art. The α and β in step S300 may be stored in a nonvolatile register.
Further, in another embodiment of the present invention, α and β may be directly obtained by a preset calculation formula without determining the sum by using the least square method. In one example, a and β may be determined based on synchronized intrathoracic pressure measurement data B and synchronized intraoral pressure measurement data M. Specifically, the method comprises the following steps:
based on
Figure BDA0002883168890000071
Determining;
based on
Figure BDA0002883168890000072
Determining;
wherein, dBj＝Bj+1-Bj，dMj＝Mj+1-Mj。
In another example, the sum may be determined based on the denoised synchronous intrathoracic pressure measurement data B 'and the synchronous intraoral pressure measurement data M', and the denoised synchronous intrathoracic pressure measurement data B 'and the synchronous intraoral pressure measurement data M' may be obtained by the same method as in the foregoing embodiment. Specifically, the method comprises the following steps:
based on
Figure BDA0002883168890000073
Determining;
based on
Figure BDA0002883168890000074
Determining;
wherein, dB'k＝B′k+1-B′k，dM′k＝M′k+1-M′kAnd n is the number of the denoised synchronous intrathoracic pressure measurement data or the denoised synchronous intraoral pressure measurement data.
In the embodiment, the sum is determined by using the preset calculation formula, so that the calculation amount can be greatly reduced and the resources can be saved for the condition that cloud calculation is needed.
Further, in the embodiment of the present invention, the processor 1 further executes a computer program for obtaining a corresponding real-time intrathoracic pressure according to the mapping relationship and the real-time intraoral pressure of the measured person within a preset time period (for example, 3s) measured by the intraoral pressure measuring apparatus, and specifically may include the following steps:
s10, acquiring an oral pressure measurement value M0 measured by an oral pressure measurement device in real time;
s20, obtaining a corresponding real-time intrathoracic pressure measured value B0 ═ α × M0+ β according to the α and the β;
and S30, displaying the real-time intrathoracic pressure measurement value B0.
In one embodiment of the present invention, for example, the real-time intrathoracic pressure measurement value B0 may be presented on a display oscilloscope of the intrathoracic pressure measurement device so that the waveform of the resulting intrathoracic pressure can be presented on the oscilloscope.
In another embodiment of the present invention, the real-time intrathoracic pressure measurement B0 may be presented on the mobile terminal of the measured person so that the measured person can use it at home. Therefore, the intrathoracic pressure measuring device according to the embodiment of the present invention may further include a communication module, which is configured to transmit the intrathoracic pressure measurement value B0 obtained in real time to a mobile terminal of the user, so as to display a waveform on the mobile terminal, and further, the mobile terminal (pad, mobile phone, etc.) may also record the intraoral pressure measurement value M0 measured in real time.
Further, in the embodiment of the present invention, the processor 1 is further configured to:
displaying an M curve of the synchronous intraoral pressure measurement data M and an M0 curve of intraoral pressure measurement value M0 obtained in real time along with time on the mobile terminal of the measured person; and
comparing the intraoral pressure data acquired in real time with the synchronized intraoral pressure measurement data based on the M curve and the M0 curve.
Generally, M is measured at the hospital and can be considered accurate, in particular synchronized with the measurement of the intrathoracic pressure measurement data B. However, M0 is measured at home and is measured in a healthy state, but may be interfered by many situations, for example, the situation of the measurement is not standard, which results in measurement error, and for example, when the measurement is performed with cough, etc., the situation brings noise of M0 measurement, which further causes B0 to fall out of the range of the warning value due to inaccuracy. Therefore, the curves of M and M0 over time may be presented on the display screen of the mobile terminal of the measured person to compare the two curves.
Further, comparing the intraoral pressure data acquired in real time with the synchronized intraoral pressure measurement data based on the M curve and the M0 curve may include:
(1) receiving one or more time pairs (S) on an M curve and an M0 curve specified by a user (measured person)k，Ek) K is 1, or>1，SkThe expression is the start time, EkIndicating the end time.
As shown in FIG. 2, the user has specified two time pairs: (S1, E1) and (S2, E2). Obviously, the location user of E1 may be designated as E11, and may also be designated as E12. The mobile terminal can prompt the user in a text or voice mode, and the time is right (S)kAnd Ek) The interval of (d) includes a peak and a valley.
Specifically, the above (1) may include:
1) receiving the starting time S specified by the user on the M0 curvekThen the start time SkAnd dragging the corresponding point to the corresponding point on the M curve customized by the user so as to align the starting points on the two curves.
2) Receiving the end time E specified by the user on the M0 curvekThen according to the start time SkAnd end time EkAutomatically marks the corresponding reception time E on the M-curvekWherein, in the M curve, the time E is endedkCoordinates on the time axis are start times SkThe sum of the time axis coordinate and the time span, i.e. the end time EkCoordinates on the time axis are start times SkTime axis coordinates + time span.
(2) Displaying a corresponding M-M0 curve on the mobile terminal based on the time-pairs.
Specifically, the time pair (S)k，Ek) The M0 curve and the M curve in between translate to the M-M0 curve. Thus, the user can visually see the comparison state after the noise is removed by M and M0.
Further, when drawing an M-M0 curve, from the M curvePart using the first color, part from the M0 curve using the second color, end time EkAnd start time Sk+1The part in between is left blank drawn, i.e. the curve between the two time pairs is not drawn, to remove noise in the curve. The first color and the second color are different.
Further, in drawing the M-M0 curve, if there is a partial overlap of the curve from the M curve and the curve from the M0 curve, the overlapped portion is drawn bold with a third color, wherein the third color value is 0.5 × first color value +0.5 × second color value. The third color is different from both the first color and the second color.
Further, when the M-M0 curve is drawn, if the time E is endedkAnd start time Sk+1Exceeds a preset threshold, e.g., 1 second, the time interval is set to the preset threshold and a time compression flag, e.g., "-", is presented on the M-M0 curve.
Thus, the M-M0 curve presented by the above contents can very intuitively display the difference between the synchronous intraoral pressure measurement data and the intraoral pressure acquired in real time, so that the measured person can clearly know the condition of the intrathoracic pressure of the measured person.
Further, in the embodiment of the present invention, on the display screen of the mobile terminal, the user drags SkIs easy to malfunction, and in order to improve the user experience, the processor 1 is further configured to:
on the display screen of the mobile terminal, the peak value and the valley value of the M curve and the M0 curve are automatically prompted, and as shown in FIG. 3 (FIG. 3 shows the M curve, and the M0 curve is also in the manner shown in FIG. 3), the peak value and the valley value of the curves are automatically amplified.
Specifically, when the user clicks on a peak of the M0 curve and drags the peak toward the M curve, all peaks on the M curve blink to guide the user to align. This way of automatically amplifying the valleys and peaks of the curve is much faster than the existing "up-scaling- > selection" way.
In summary, the intrathoracic pressure measurement device provided by the embodiment of the present invention determines the mapping relationship between the intrathoracic pressure and the intraoral pressure by the intrathoracic pressure measurement data of invasive measurement and the intraoral pressure measurement data of simultaneous intraoral pressure measurement, and thus, the mapping relationship is accurate. When the intrathoracic pressure needs to be measured, according to the determined mapping relation, the user can directly obtain the corresponding intrathoracic pressure at home through measuring the intraoral pressure, the time for the user to go to a hospital for measurement can be reduced, discomfort caused by invasive measurement can be avoided, and the method is simple, convenient and accurate and has good user experience. And the obtained real-time intrathoracic pressure curve and the curve corresponding to the synchronous intraoral pressure measurement data can be displayed on a mobile terminal of a user, so that the user can intuitively know the difference between the two, and the visualization effect is good.
The above-mentioned embodiments are only specific embodiments of the present invention, which are used for illustrating the technical solutions of the present invention and not for limiting the same, and the protection scope of the present invention is not limited thereto, although the present invention is described in detail with reference to the foregoing embodiments, those skilled in the art should understand that: any person skilled in the art can modify or easily conceive the technical solutions described in the foregoing embodiments or equivalent substitutes for some technical features within the technical scope of the present disclosure; such modifications, changes or substitutions do not depart from the spirit and scope of the embodiments of the present invention, and they should be construed as being included therein. Therefore, the protection scope of the present invention shall be subject to the protection scope of the claims.

Claims (10)

1. An intrathoracic pressure measurement device, comprising: the system comprises a processor, a synchronous database and an intraoral pressure measuring device;
the synchronous database stores synchronous intrathoracic pressure measurement data B ═ B (B) of the measured person1，B2，......，Bm) And synchronous intraoral pressure measurement data M ═ (M1, M)2，......Mm) When the synchronous intrathoracic pressure measurement data and the synchronous intraoral pressure measurement data are used for invasive measurement of intrathoracic pressure of the measured person,simultaneously carrying out intraoral pressure measurement, wherein BiAnd MiRespectively obtaining a synchronous intrathoracic pressure value and an intraoral pressure value sampled and obtained at the ith preset time dt, wherein the value of i is 1.. m;
the processor is used for determining the mapping relation between the intrathoracic pressure and the intraoral pressure of the measured person according to the synchronous intrathoracic pressure measurement data and the synchronous intraoral pressure measurement data, and obtaining the corresponding real-time intrathoracic pressure according to the mapping relation and the real-time intraoral pressure of the measured person within the preset time period measured by the intraoral pressure measurement device; the mapping relation between the intrathoracic pressure and the intra-oral pressure is as follows: b ═ α × M + β, α and β are coefficients of the mapping relationships, respectively.
2. The intrathoracic pressure measurement device of claim 1, wherein the determining of the mapping relationship between intrathoracic pressure and intraoral pressure of the subject from the synchronized intrathoracic pressure measurement data and the synchronized intraoral pressure measurement data comprises the steps of:
s100, denoising the synchronous intrathoracic pressure measurement data B and the synchronous intraoral pressure measurement data M to obtain denoised synchronous intrathoracic pressure measurement data B 'and synchronous intraoral pressure measurement data M';
s200, determining alpha and beta by adopting a least square method according to the synchronous intrathoracic pressure measurement data B 'and the synchronous intraoral pressure measurement data M' which are subjected to denoising treatment;
and S300, storing the alpha and the beta.
3. The intrathoracic pressure measurement device of claim 2, wherein S100 further comprises:
s110, obtaining difference data dB (dB) of synchronous intrathoracic pressure measurement data B1，dB2，...，dBm-1) Difference data dM ═ dM of the synchronous intraoral pressure measurement data M1，dM2，...，dMm-1) Wherein, dBj＝Bj+1-Bj，dMj＝Mj+1-MjJ has a value of 1. (m-1);
s120, if dBj-dMjIf it is greater than the preset threshold, then B will bej+1And Mj+1And removing noise points to obtain synchronous intrathoracic pressure measurement data B 'and synchronous intraoral pressure measurement data M' after noise removal.
4. The intrathoracic pressure measurement device of claim 2, wherein S100 further comprises:
s130, obtaining difference data dB (dB) of synchronous intrathoracic pressure measurement data B1，dB2，...，dBm-1) Difference data dM ═ dM of the synchronous intraoral pressure measurement data M1，dM2，...，dMm-1) Wherein, dBj＝Bj+1-Bj，dMj＝Mj+1-MjJ has a value of 1. (m-1);
s140, if Bi+1≥BiIf the value of dBi is equal to the first identifier, otherwise, dBi is equal to the second identifier; and if Mi+1≥MiThen dMi is the first identifier, otherwise dMi is the second identifier; the first identifier and the second identifier are different;
s150, if dBiNot equal to dMiThen B will bei+1And Mi+1As the noise point removal, B 'and M' after noise removal are obtained.
5. The intrathoracic pressure measurement device of claim 1, wherein determining the mapping relationship between intrathoracic pressure and intraoral pressure of the subject based on the synchronized intrathoracic pressure measurement data and the synchronized intraoral pressure measurement data comprises:
a is based on
Figure FDA0002883168880000021
Determining;
said beta is based on
Figure FDA0002883168880000022
Determining;
wherein, dBj＝Bj+1-Bj，dMj＝Mj+1-Mj。
6. The intrathoracic pressure measurement device of claim 1, wherein the obtaining of the corresponding real-time intrathoracic pressure based on the mapping relationship and the real-time intraoral pressure of the subject measured by the intraoral pressure measurement device over a preset time period comprises:
s10, acquiring an oral pressure measurement value M0 measured by an oral pressure measurement device in real time;
s20, obtaining a corresponding real-time intrathoracic pressure measured value B0 ═ α × M0+ β according to the α and the β;
and S30, displaying the real-time intrathoracic pressure measurement value B0.
7. The intrathoracic pressure measurement device of claim 6, wherein the processor is further configured to:
displaying an M curve of the synchronous intraoral pressure measurement data M and an M0 curve of intraoral pressure measurement value M0 obtained in real time along with time on the mobile terminal of the measured person; and
comparing the intraoral pressure data acquired in real time with the synchronized intraoral pressure measurement data based on the M curve and the M0 curve.
8. The intrathoracic pressure measurement device of claim 7, wherein comparing the intraoral pressure data acquired in real time and the synchronized intraoral pressure measurement data based on the M curve and the M0 curve comprises:
receiving one or more time pairs (S) on the M curve and the M0 curve specified by the userk，Ek) K is 1, or>1，SkThe expression is the start time, EkRepresents an end time;
displaying a corresponding M-M0 curve on the mobile terminal based on the time-pairs.
9. Intrathoracic pressure measurement according to claim 8Means, characterized in that said receiving user specified M-curve and one or more time pairs (S) on M0 curvek，Ek) The method comprises the following steps:
receiving the starting time S specified by the user on the M0 curvekThen the start time SkDragging the corresponding point to the corresponding point on the M curve;
receiving the end time E specified by the user on the M0 curvekThen according to the start time SkAnd end time EkAutomatically marks the corresponding reception time E on the M-curvekWherein, in the M curve, the time E is endedkCoordinates on the time axis are start times SkThe sum of the time axis coordinate and the time span.
10. The intrathoracic pressure measurement device of claim 9, wherein the displaying of the corresponding M-M0 curve on the mobile terminal based on the time-pairs comprises:
time pair (S)k，Ek) The M curve in between and the M0 curve translate to the M-M0 curve.
CN202110005877.XA 2021-01-05 2021-01-05 Intrathoracic pressure measuring device Active CN112790754B (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CN202110005877.XA CN112790754B (en) 2021-01-05 2021-01-05 Intrathoracic pressure measuring device
PCT/CN2021/094878 WO2022147944A1 (en) 2021-01-05 2021-05-20 Intrapleural pressure measurement apparatus

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202110005877.XA CN112790754B (en) 2021-01-05 2021-01-05 Intrathoracic pressure measuring device

Publications (2)

Publication Number Publication Date
CN112790754A true CN112790754A (en) 2021-05-14
CN112790754B CN112790754B (en) 2021-11-09

Family

ID=75808033

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202110005877.XA Active CN112790754B (en) 2021-01-05 2021-01-05 Intrathoracic pressure measuring device

Country Status (2)

Country Link
CN (1) CN112790754B (en)
WO (1) WO2022147944A1 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022147945A1 (en) * 2021-01-05 2022-07-14 中国医学科学院北京协和医院 Visual intrapleural pressure measurement apparatus
WO2022147944A1 (en) * 2021-01-05 2022-07-14 中国医学科学院北京协和医院 Intrapleural pressure measurement apparatus

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4452252A (en) * 1981-05-26 1984-06-05 Respitrace Corporation Non-invasive method for monitoring cardiopulmonary parameters
US4456015A (en) * 1981-05-26 1984-06-26 Respitrace Corporation Non-invasive method for semiquantitative measurement of neck volume changes
US4860766A (en) * 1983-11-18 1989-08-29 Respitrace Corp. Noninvasive method for measuring and monitoring intrapleural pressure in newborns
CN105530860A (en) * 2013-06-28 2016-04-27 皇家飞利浦有限公司 Non-invasive estimation of intra-pleural pressure and/or computation of work of breathing based on a non-invasive estimation of intra-pleural pressure
CN107613865A (en) * 2015-08-06 2018-01-19 株式会社电装 Intrathoracic pressure computing device and intrathoracic pressure computational methods

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112790754B (en) * 2021-01-05 2021-11-09 中国医学科学院北京协和医院 Intrathoracic pressure measuring device

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4452252A (en) * 1981-05-26 1984-06-05 Respitrace Corporation Non-invasive method for monitoring cardiopulmonary parameters
US4456015A (en) * 1981-05-26 1984-06-26 Respitrace Corporation Non-invasive method for semiquantitative measurement of neck volume changes
US4860766A (en) * 1983-11-18 1989-08-29 Respitrace Corp. Noninvasive method for measuring and monitoring intrapleural pressure in newborns
CN105530860A (en) * 2013-06-28 2016-04-27 皇家飞利浦有限公司 Non-invasive estimation of intra-pleural pressure and/or computation of work of breathing based on a non-invasive estimation of intra-pleural pressure
CN107613865A (en) * 2015-08-06 2018-01-19 株式会社电装 Intrathoracic pressure computing device and intrathoracic pressure computational methods

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022147945A1 (en) * 2021-01-05 2022-07-14 中国医学科学院北京协和医院 Visual intrapleural pressure measurement apparatus
WO2022147944A1 (en) * 2021-01-05 2022-07-14 中国医学科学院北京协和医院 Intrapleural pressure measurement apparatus

Also Published As

Publication number Publication date
CN112790754B (en) 2021-11-09
WO2022147944A1 (en) 2022-07-14

Similar Documents

Publication Publication Date Title
CN112790754B (en) Intrathoracic pressure measuring device
CN106163388B (en) Processing device and method for processing cardiac data of a living being
US11026591B2 (en) Intravascular pressure sensor calibration
JP2018510683A5 (en)
CN104248438A (en) Apparatus for determining respiratory condition
JPWO2013089072A1 (en) Information management apparatus, information management method, information management system, stethoscope, information management program, measurement system, control program, and recording medium
US12114969B2 (en) Hypoventilation monitoring system and method
US20210244901A1 (en) Method and apparatus for determining a regional compliance of a lung during spontaneous respiration
JP7550178B2 (en) Providing guidance during medical procedures
JP6522327B2 (en) Pulse wave analyzer
Hersh et al. Validation of a conical cuff on the forearm for estimating radial artery blood pressure
CN104173033B (en) Equipment for testing respiratory function
CN112826489B (en) Visual intracavity pressure measuring device
CN107205672A (en) For the apparatus and method for the breath data for assessing monitoring object
CN109589137B (en) Fetal movement identification method, fetal movement identification device, terminal and computer-readable storage medium
JP2014036847A (en) Frequency domain analysis transform of renal blood flow doppler signal to determine stress level
Nakayama et al. A Practical Training Program for peripheral radial artery catheterization in adult patients: a prospective, randomized controlled trial
CN112107767B (en) Monitoring index providing method and device, ventilation equipment and storage medium
JP2022085424A (en) Information generation device, information generation method, computer program, and non-temporary computer readable medium
WO2020090763A1 (en) Processing device, system, processing method, and program
US20200345275A1 (en) A method for measuring a sedation state of a patient
Yoon et al. Blood Pressure Measurement Based on the Camera and Inertial Measurement Unit of a Smartphone
CN112716525B (en) Fetal heart rate processing method and device and readable storage medium
EP4371596A1 (en) Cardiogenic interference identification method for medical ventilation device, and medical ventilation device
US20210007677A1 (en) Diagnostic assistance system, diagnostic assistance method, and diagnostic assistance program

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant