CN112790721B - High-resolution lateral imaging miniature endoscopic microscope objective group and probe - Google Patents

High-resolution lateral imaging miniature endoscopic microscope objective group and probe Download PDF

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CN112790721B
CN112790721B CN202110123542.8A CN202110123542A CN112790721B CN 112790721 B CN112790721 B CN 112790721B CN 202110123542 A CN202110123542 A CN 202110123542A CN 112790721 B CN112790721 B CN 112790721B
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lens
end surface
image
microscope objective
imaging
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CN112790721A (en
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王立强
郭飞
杨青
游兴海
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Zhejiang University ZJU
Zhejiang Lab
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Zhejiang Lab
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00163Optical arrangements
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/06Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
    • A61B1/07Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements using light-conductive means, e.g. optical fibres
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B1/00Optical elements characterised by the material of which they are made; Optical coatings for optical elements
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/0004Microscopes specially adapted for specific applications
    • G02B21/002Scanning microscopes
    • G02B21/0024Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0052Optical details of the image generation
    • G02B21/0076Optical details of the image generation arrangements using fluorescence or luminescence

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Abstract

The invention relates to a miniature endoscopic microscope objective group and a probe for high-resolution lateral imaging, which comprise a first prism, a first lens, a second lens, a third lens, a fourth lens and an imaging surface which are sequentially arranged from an object side, wherein each lens of the miniature microscope objective group is provided with parameters which are matched with each other, so that when the clear aperture of the miniature microscope objective group is smaller than 0.8mm, the working distance is 40-80 mu m under the wavelength of 488nm, the magnification is 1.9-2.1, and the visual field can reach 290 mu m. The lateral imaging miniature endoscopic microscope objective group can observe the tissue structure of the side wall of a narrow pancreatic duct, and can better cooperate with an optical fiber bundle to observe tissue cells by utilizing a confocal technology.

Description

High-resolution lateral imaging miniature endoscopic microscope objective group and probe
Technical Field
The invention relates to the technical field of medical imaging, in particular to a miniature endoscopic microscope objective group and a probe for high-resolution lateral imaging.
Background
The key problem of multi-organ diagnosis and treatment integration is multi-azimuth stereoscopic imaging in a narrow space. Optical fiber endoscope is a major breakthrough of flexible endoscope technology, so that a flexible imaging probe can flexibly conduct steering observation in a body, however, in a narrow area, the probe cannot be bent at a large angle due to small space, so that omission frequently occurs in the pancreatic duct area clinically, and the optical fiber endoscope technology for multi-direction observation is still an urgent practical problem. Therefore, in a narrow space, a miniature lateral imaging device with high resolution at the cell level is very important for early diagnosis of canceration in areas such as pancreatic duct.
In order to solve the above-mentioned problems, a large field-of-view micro-objective lens is disclosed in chinese patent publication No. CN 110764226A, which has an outer diameter of 2.6mm, and sequentially comprises a first lens having positive refractive power, a second lens having positive refractive power, a third lens, a fourth lens having positive refractive power, a fifth lens having negative refractive power, a sixth lens having negative refractive power, and an imaging plane from an object side to an image side along an optical axis direction thereof. The device can be matched with a fluorescence confocal endoscope for use, enters a human body through a working channel of a conventional enteroscope to carry out clinical diagnosis of intestinal diseases, but the device cannot realize lateral imaging.
Another example of the chinese patent publication No. CN 107003502A discloses an endoscope objective optical system capable of changing the visual field in an arbitrary direction without bending the endoscope even in a narrow space. The endoscope objective optical system is composed of an optical path deflecting prism group and a lens group, and the direction of the field of view of the endoscope objective optical system is changeable by moving the prism in the optical path deflecting prism group. The device can change the visual field to any direction without bending the endoscope, but the diameter of the device exceeds 5mm, and the device cannot enter a narrow part of a human body middle cavity.
At present, no endoscope equipment capable of entering narrow channels such as pancreatic channels and simultaneously realizing lateral imaging exists at home and abroad, a miniature endoscopic microscope objective group and a probe for high-resolution lateral imaging are designed, and meanwhile, the miniature endoscopic microscope objective group and the probe have the capabilities of small size and lateral imaging, and have practical significance and good application prospects in early detection of pancreatic channel canceration.
Disclosure of Invention
The invention aims at overcoming the defects of the prior art, and provides a miniature endoscopic microscope objective group and a probe which can be matched with an optical fiber bundle to observe a cell structure and perform high-resolution lateral imaging.
The application discloses a miniature endoscopic microscope objective group for high-resolution lateral imaging, which sequentially comprises a first prism, a first lens, a second lens, an opening diaphragm, a third lens, a fourth lens and an imaging surface from an object side; the first prism is a 45-degree right-angle prism and is provided with a first object end surface, a first reflecting surface and a first image end surface; the first lens is a plano-convex lens and is provided with a second object end surface and a second image end surface; the second lens is a double-cemented lens formed by combining a positive lens and a negative lens, the positive lens is provided with a third object end surface and a third image end surface, the negative lens is provided with a fourth object end surface and a fourth image end surface, and the third image end surface and the fourth object end surface are in close contact superposition; the third lens is a meniscus lens and is provided with a fifth object end surface and a fifth image end surface; the fourth lens is a convex flat lens and is provided with a sixth object end surface and a sixth image end surface; the second object end surface and the sixth image end surface are planes, the second image end surface, the third object end surface, the third image end surface, the fourth image end surface, the fifth object end surface and the sixth object end surface are convex surfaces, the fourth object end surface and the fifth image end surface are concave surfaces, the clear aperture of the high-resolution lateral imaging miniature endoscope microscope objective group is smaller than 0.8mm, and the high-resolution lateral imaging miniature endoscope microscope objective group meets the following relation:
0.9<f dou /f<1.6;
0.5<Las/L 0 <0.6;
wherein f dou F is the effective focal length of the miniature endoscopic microscope objective group for high-resolution lateral imaging, L 0 A distance from the first object end surface of the first prism to the aperture stop along the optical axis for the high-resolution lateral imaging miniature endoscope lens group, wherein Las is a distance from the first object end surface of the first prism to the imaging surface along the optical axis for the high-resolution lateral imaging miniature endoscope lens group;
preferably, the first prism is made of medium refractive index high hardness glass, the first lens is made of low refractive index glass, the second lens is made of a combination of high refractive index low dispersion coefficient glass and high refractive index high dispersion coefficient glass, the third lens is made of high refractive index glass, and the fourth lens is made of high refractive index glass.
Preferably, the first prism, the first lens, the second lens, the third lens, and the fourth lens satisfy the following conditions: R21S >0, R22S <0; R31S >0, R32S <0; R42S < R41S <0; R51S > R52S >0; R62S > R61S >0; wherein R21S is a radius of curvature of a second object surface of the first lens; R22S is a radius of curvature of the second image-side surface of the first lens; R31S is the radius of curvature of the third object-side surface of the second lens; R32S is a radius of curvature of the third image-side surface of the second lens; R41S is the radius of curvature of the fourth object-side surface of the second lens; R42S is a radius of curvature of the fourth image-side surface of the second lens; R51S is a radius of curvature of a fifth object-side surface of the third lens; R52S is a radius of curvature of the fifth image-side surface of the third lens; R61S is a radius of curvature of a sixth object-side surface of the fourth lens; R62S is a radius of curvature of the sixth image-side surface of the fourth lens.
Preferably, the miniature endoscopic microscope objective group for high resolution lateral imaging satisfies the following relationship: 1.1< Lst/La <1.3;
wherein Lst is a distance on an optical axis from a second object end surface of the first lens to the aperture stop, and La is a distance on an optical axis from a second object end surface of the first lens to a fourth image end surface of the second lens.
Preferably, the miniature endoscopic microscope objective group for high resolution lateral imaging satisfies the following relationship: 1.2< La/f <2.1;
wherein La is the distance from the second end surface of the first lens to the fourth end surface of the second lens on the optical axis, and f is the effective focal length of the miniature endoscopic microscope objective group for high-resolution lateral imaging.
Preferably, the high resolutionThe miniature endoscopic microscope objective group for lateral imaging satisfies the following relationship: 0.2<f b /f<0.4;
Wherein f b And f is the effective focal length of the miniature endoscopic microscope objective group for high-resolution lateral imaging.
The application also discloses a probe, including lens cone and protection gasket, the inside miniature endoscopic microscope objective group that is equipped with high resolution side direction formation of image of lens cone, the front end side of lens cone is equipped with the light inlet, the light inlet is located the first object terminal surface of first prism, the front end of lens cone is equipped with protection gasket.
Preferably, a plurality of spacers and an optical fiber bundle for imaging are arranged in the lens barrel, the optical fiber bundle is positioned at the rear end of the fourth lens, the spacers comprise a first spacer positioned between the first lens and the second lens, a second spacer positioned between the second lens and the third lens, a third spacer positioned between the third lens and the fourth lens and a fourth spacer positioned between the fourth lens and the optical fiber bundle.
Preferably, the side wall of the lens barrel is provided with an observation hole which is convenient for determining the position of the end face of the optical fiber during assembly.
Preferably, the number of the observation holes is 2, and the two observation holes are located at opposite positions on the side wall of the lens barrel.
The invention has the beneficial effects that: the high-resolution micro-objective lens group capable of laterally imaging for the human body tiny cavity can carry out fluorescence imaging by means of fluorescent substances under the excitation of laser with wavelength of 488nm, and can conveniently observe the side wall of the cavity within the working distance of 40-80 mu m; because the micro-microscope objective has 2 times of magnification, the micro-microscope objective can be well matched with an optical fiber bundle to realize the observation of tissue cells.
The features and advantages of the present invention will be described in detail by way of example with reference to the accompanying drawings.
Drawings
FIG. 1 is a schematic view of the optical path structure of a miniature endoscopic microscope objective unit for high resolution lateral imaging provided by the invention;
FIG. 2 is a schematic view of a miniature endoscopic microscope objective probe for high resolution lateral imaging provided by the invention;
fig. 3 is an image space spherical aberration curve, an image space field curvature curve and a distortion curve of embodiment 1;
FIG. 4 is the MTF curve of example 1;
fig. 5 is an image space spherical aberration curve, an image space field curvature curve and a distortion curve of embodiment 2;
FIG. 6 is an MTF curve of example 2;
fig. 7 is an image space spherical aberration curve, an image space field curvature curve and a distortion curve of embodiment 3;
FIG. 8 is an MTF curve of example 3;
fig. 9 is an image space spherical aberration curve, an image space field curvature curve and a distortion curve of embodiment 4;
FIG. 10 is the MTF curve of example 4;
fig. 11 is an image space spherical aberration curve, an image space field curvature curve, and a distortion curve of example 5;
FIG. 12 is the MTF curve of example 5;
in the figure: 10-first prism, 20-first lens, 30-positive lens, 40-negative lens, 50-third lens, 60-fourth lens, 90-optical fiber bundle, 100-lens barrel, 110-protective gasket, 120-first space ring, 130-second space ring, 140-third space ring, 150-fourth space ring, K1-light entrance, K2-observation hole, S11-first object end surface, S12-first reflection surface, S13-first image end surface, S21-second object end surface, S22-second image end surface, S31-third object end surface, S32-third image end surface, S41-fourth object end surface, S42-fourth image end surface, S51-fifth object end surface, S52-fifth image end surface, S61-sixth object end surface, S62-sixth image end surface.
Detailed Description
The present invention will be further described in detail with reference to the drawings and examples, in order to make the objects, technical solutions and advantages of the present invention more apparent. It should be understood that the detailed description and specific examples, while indicating the invention, are intended for purposes of illustration only and are not intended to limit the scope of the invention. In addition, in the following description, descriptions of well-known structures and techniques are omitted so as not to unnecessarily obscure the present invention.
Referring to fig. 1, the present invention provides a miniature endoscopic microscope objective with high resolution and lateral imaging, comprising a first prism 10, a first lens 20, second lenses 30 and 40, a third lens 50, a fourth lens 60 and an imaging surface 70, which are sequentially arranged from the object side, wherein each lens of the miniature endoscopic microscope objective has parameters adapted so that the working distance is 40-80 μm and the field of view can reach 290 μm at a wavelength of 488nm when the clear aperture of the miniature endoscopic microscope objective is smaller than 0.8 mm. Light rays emitted from the object plane sequentially pass through the first prism 10, the first lens 20, the second lenses 30 and 40, the third lens 50 and the fourth lens 60 and then are imaged on the imaging plane 70; the first prism 10 is a 45 ° right angle prism for turning the light path to enable the system to image a lateral object, and the first prism 10 includes a first object end surface S11, a first reflecting surface S12 and a first image end surface S13; the first lens 20 is a plano-convex lens, and is conveniently in direct contact with the prism at the front end. The first lens 20 includes a second object-side surface S21 and a second image-side surface S22. The second object surface S21 is a plane, so as to be convenient to be in close contact with and coincide with the first image end surface S13 of the first prism 10; the second lens is a double-cemented lens formed by combining a lens 30 and a lens 40, and aberration is corrected by respectively matching a glass material with a high refractive index and a low dispersion coefficient with a glass material with a high refractive index and a high dispersion coefficient; the lens 30 includes a third object-side surface S31 and a third image-side surface S32; the lens 40 includes a fourth object-side surface S41 and a fourth image-side surface S42, and the third image-side surface S32 is in close contact with the fourth object-side surface S41; the third lens 50 is a thick meniscus lens, which can be used to correct field curvature, and is a high refractive index glass material. The third lens 50 includes a fifth object-side surface S51 and a fifth image-side surface S52; the fourth lens 60 is a convex flat lens, which is convenient to couple with the optical fiber at the rear end, and is used for compensating residual aberration, and glass material with high refractive index is selected. The fourth lens 60 comprises a sixth object-side surface S61 and a sixth image-side surface S62; the second object surface S21 is a plane, which is convenient to be in direct contact with the first image end surface S13 of the first prism. The sixth image end surface S62 is planar to facilitate coupling and interfacing with the fiber bundle. The second image end surface S22, the third object end surface S31, the third image end surface S32, the fourth image end surface S42, the fifth object end surface S51 and the sixth object end surface S61 are convex; the fourth object end surface S41 and the fifth image end surface S52 are concave; namely, the miniature endoscopic microscope objective group for high-resolution lateral imaging meets the following conditions:
(1)R21S>0,R22S<0;
(2)R31S>0,R32S<0;
(3)R42S<R41S<0;
(4)R51S>R52S>0;
(5)R62S>R61S>0;
wherein R21S is the radius of curvature of the second object surface S21 of the first lens; R22S is the radius of curvature of the second image-side surface S22 of the first lens; R31S is the radius of curvature of the third object-side surface S31 of the second lens; R32S is the radius of curvature of the third image-side surface S32 of the second lens; R41S is the radius of curvature of the fourth object-end surface S41 of the second lens; R42S is the radius of curvature of the fourth image-side surface S42 of the second lens; R51S is the radius of curvature of the fifth object-end surface S51 of the third lens; R52S is the radius of curvature of the fifth image-side surface S52 of the third lens; R61S is the radius of curvature of the sixth object-side surface S61 of the fourth lens; R62S is the radius of curvature of the sixth image-side surface S62 of the fourth lens.
The miniature endoscopic microscope objective lens group for high-resolution lateral imaging has processability, and all the curvature radius R of the lens, the thickness CT of the middle lens, the thickness ET of the side of the lens and the thickness AT of the air gap meet the following conditional expression:
(1)R>0.5mm
(2)CT>0.4mm
(3)ET>0.4mm
(4)AT>0.2mm
specific examples of a high resolution lateral imaging miniature endoscopic microscope objective with an outer diameter less than 1.2mm are as follows:
example 1
The lens structure of the objective lens for endoscope of example 1 is as shown in fig. 1, the outer diameter of the miniature endoscopic microscope objective lens group for high resolution lateral imaging provided in example 1 is 0.8mm, the aperture is smaller than 0.6mm, specific lens data of each lens are shown in table 1, the specification is shown in table 2, and each aberration diagram is shown in fig. 3 to 4:
TABLE 1
TABLE 2
TTL/mm 5.4
Object distance/μm 60
Object field of view/. Mu.m 296
F number 5.05
In the miniature endoscopic microscope objective group for high-resolution lateral imaging in the embodiment 1, the diameter of the probe with a shell, which is made of the miniature endoscopic microscope objective group, is less than or equal to 1mm because the outer diameter of the lens is 0.8mm, the clear aperture is less than 0.6mm, and the thickness of the conventional shell is 0.1 mm.
Example 2
The outer diameter of the miniature endoscopic microscope objective set for high resolution lateral imaging provided in example 2 is 0.9mm, the aperture is smaller than 0.7mm, the specific lens data of each lens are shown in table 3, the specification is shown in table 4, and the aberration diagrams are shown in fig. 5 to 6:
TABLE 3 Table 3
TABLE 4 Table 4
TTL/mm 5.45
Object distance/μm 60
Object field of view/. Mu.m 304
F number 4.09
In the miniature endoscopic microscope objective group for high-resolution lateral imaging in the embodiment 2, the diameter of the miniature endoscopic microscope objective group for high-resolution lateral imaging is smaller than 0.7mm because the outer diameter of the miniature endoscopic microscope objective group is 0.9mm, the clear aperture of the miniature endoscopic microscope objective group is smaller than 0.7mm, and the thickness of a conventional shell is 0.1mm, so that the diameter of a probe with a shell, which is made of the miniature endoscopic microscope objective group, is smaller than or equal to 1.1mm.
Example 3
The external diameter of the miniature endoscopic microscope objective set for high-resolution lateral imaging provided in example 3 is 1mm, the aperture of light transmission is less than 0.8mm, the specific lens data of each lens are shown in table 5, the specification is shown in table 6, and the aberration diagrams are shown in fig. 7 to 8:
TABLE 5
TABLE 6
TTL/mm 5.77
Object distance/μm 60
Object field of view/. Mu.m 317
F number 3.68
In the miniature endoscopic microscope objective group for high-resolution lateral imaging in the embodiment 3, the diameter of the miniature endoscopic microscope objective group for high-resolution lateral imaging is smaller than 0.8mm because the outer diameter of the miniature endoscopic microscope objective group is 1mm, and the diameter of a probe with a shell, which is made of the miniature endoscopic microscope objective group, is smaller than 1.2mm because the clear aperture of the miniature endoscopic microscope objective group is smaller than 0.1mm, and the thickness of a conventional shell is smaller than 0.1 mm.
Example 4
Example 4 provides a high resolution side-imaging miniature endoscopic microscope objective with an object distance of 40 μm, specific lens data for each lens are shown in table 7, and specifications are shown in table 8, and aberrations are shown in fig. 9 to 10:
TABLE 7
TABLE 8
TTL/mm 5.22
Light-transmitting aperture/mm <0.6mm
Object field of view/. Mu.m 296
F number 5.11
In the miniature endoscopic microscope objective group for high-resolution lateral imaging in the embodiment 4, the diameter of the probe with the shell, which is made of the miniature endoscopic microscope objective group, is less than or equal to 1mm because the clear aperture is less than 0.6mm and the thickness of the conventional shell is 0.1 mm.
Example 5
Example 5 provides a high resolution side-imaging miniature endoscopic microscope objective with an object distance of 80 μm, specific lens data for each lens are shown in table 9, and specifications are shown in table 10, with aberrations shown in fig. 11-12:
TABLE 9
Table 10
TTL/mm 5.2
Light-transmitting aperture/mm <0.6mm
Object field of view/. Mu.m 296
F number 5.12
In the miniature endoscopic microscope objective group for high-resolution lateral imaging in the embodiment 5, the diameter of a probe with a shell, which is made of the miniature endoscopic microscope objective group, is less than or equal to 1mm because the clear aperture is less than 0.6mm and the thickness of a conventional shell is 0.1 mm.
The spherical aberration curves, astigmatic curves, distortion curves, MTF curves of the respective clear apertures of a high resolution side-view imaging miniature endoscope objective set of examples 1-3 were approximated; the spherical aberration curve, astigmatic curve, distortion curve, MTF curve of a miniature endoscopic microscope objective set for high resolution lateral imaging at different object distances described in examples 1, 4, 5 are close to each other, so only example 1 is selected for detailed description. The method comprises the following steps:
fig. 3 shows, in order from the left, aberration diagrams of the high-resolution side-view imaging miniature endoscope of example 1, showing spherical aberration, astigmatism, and distortion. In the spherical aberration graph, the spherical aberration curve is shown with a solid line. In the astigmatism graph, aberration in the meridian plane is shown by a solid line, and aberration in the sagittal plane is shown by a broken line. In the distortion graph, the distortion aberration of the system is shown with a solid line.
The symbols, meanings, and description methods of the respective data described in the description of the above embodiment 1 are the same as those of the following embodiments unless otherwise specified, and therefore, duplicate descriptions are omitted below.
Fig. 4 is a graph showing MTF curves corresponding to meridian and sagittal planes at four different positions of 0-150cy/mm in frequency, 0.15mm (0.5 field of view), 0.2mm (0.707 field of view), 0.3mm (edge field of view) and comparing the MTF curves under diffraction limit conditions. The 8 MTF curves are all different from the MTF curve under the diffraction limit condition. The fiber bundle core diameter is about 3.5 μm, i.e. the pixel size is 3.5 μm, corresponding to a cut-off frequency of 143lp/mm. As shown, at a frequency of 150cy/mm, the full field of view MTF >0.43 meets a design criterion of greater than 0.4. The design resolution can be considered to be satisfactory.
The conditional expressions (1) - (5) and the corresponding parameter values involved for one high resolution side-imaging miniature endoscopic microscope objective set of examples 1-5 are shown in table 11. The values shown in Table 11 are based on 488nm wavelength:
TABLE 11
Numbering device Parameters (parameters) Example 1 Example 2 Example 3 Example 4 Example 5
1 Lst 2.00 2.03 2.41 1.95 1.92
2 La 1.74 1.75 1.91 1.69 1.65
3 Lst/La 1.15 1.16 1.26 1.15 1.16
4 f dou 1.32 1.38 2.01 1.30 1.32
5 f 0.86 1.07 1.47 1.35 1.32
6 f dou /f 1.54 1.29 1.36 0.96 1.00
7 La/f 2.02 1.64 1.30 1.25 1.25
8 fb 0.31 0.30 0.30 0.30 0.30
9 fb/f 0.36 0.28 0.20 0.22 0.23
10 Las 2.72 2.75 3.13 2.67 2.64
11 L 0 5.10 5.15 5.47 4.92 4.90
12 Las/L 0 0.53 0.53 0.57 0.54 0.54
From the above data, it can be seen that a miniature endoscopic microscope objective set for high resolution lateral imaging of examples 1-5 is an optical system of 1 prism plus 4 lens (including a double cemented lens) structure, and the outer diameter of the objective set is smaller than 1mm, and is constructed as a miniature. The 1 prism can turn the light path by 90 degrees to form lateral imaging. The resolution of the imaging surface of the objective lens group reaches 150cy/mm, the requirement of the optical fiber bundle can be met, the diameter of the fiber core of the optical fiber bundle is about 3.5 mu m, and the objective lens group has 2 times of magnification, can realize object space resolution smaller than 2 mu m, and is constructed to be high resolution.
Fig. 2 is a schematic overall configuration view of the endoscope. The endoscope probe shown in fig. 2 mainly includes a lens barrel 100, a protective spacer 110, a plurality of spacers included in the lens barrel, including a first spacer 120 between the lenses 20 and 30, a second spacer 130 between the lenses 40 and 50, a third spacer 140 between the lenses 50 and 60, and a fourth spacer 150 between the lenses 60 and the optical fiber bundle 90, and the optical fiber bundle 90 for imaging.
The lens barrel 100 is characterized in that it has an opening K1 to facilitate light from the lateral direction to enter the lens; the side wall of the device is provided with small holes K2, and the number of the small holes is two, and the small holes are arranged at opposite positions, so that the device is convenient to assemble and position.
The foregoing description of the preferred embodiments of the invention is not intended to be limiting, but rather is intended to cover all modifications, equivalents, or alternatives falling within the spirit and principles of the invention.

Claims (10)

1. A miniature endoscopic microscope objective group for high resolution lateral imaging, which is characterized in that: the lens comprises a first prism, a first lens, a second lens, an opening diaphragm, a third lens, a fourth lens and an imaging surface in sequence from the object side; the first prism is a 45-degree right-angle prism and is provided with a first object end surface, a first reflecting surface and a first image end surface; the first lens is a plano-convex lens and is provided with a second object end surface and a second image end surface; the second lens is a double-cemented lens formed by combining a positive lens and a negative lens, the positive lens is provided with a third object end surface and a third image end surface, the negative lens is provided with a fourth object end surface and a fourth image end surface, and the third image end surface and the fourth object end surface are in close contact superposition; the third lens is a meniscus lens and is provided with a fifth object end surface and a fifth image end surface; the fourth lens is a convex flat lens and is provided with a sixth object end surface and a sixth image end surface; the second object end surface and the sixth image end surface are planes, the second image end surface, the third object end surface, the third image end surface, the fourth image end surface, the fifth object end surface and the sixth object end surface are convex surfaces, the fourth object end surface and the fifth image end surface are concave surfaces, the clear aperture of the high-resolution lateral imaging miniature endoscope microscope objective group is smaller than 0.8mm, and the high-resolution lateral imaging miniature endoscope microscope objective group meets the following relation:
0.9<f dou /f<1.6;
0.5<Las/L 0 <0.6;
wherein f dou F is the effective focal length of the miniature endoscopic microscope objective group for high-resolution lateral imaging, L 0 And Las is the distance from the first object end surface of the first prism to the imaging surface along the optical axis.
2. A high resolution side-imaging miniature endoscope objective lens set according to claim 1 and wherein: the first lens is made of medium-refractive-index high-hardness glass, the first lens is made of low-refractive-index glass, the second lens is made of a combination of high-refractive-index low-dispersion-coefficient glass and high-refractive-index high-dispersion-coefficient glass, the third lens is made of high-refractive-index glass, and the fourth lens is made of high-refractive-index glass.
3. A high resolution side-imaging miniature endoscope objective lens set according to claim 1 and wherein: the first prism, the first lens, the second lens, the third lens and the fourth lens meet the following conditions: R21S >0, R22S <0; R31S >0, R32S <0; R42S < R41S <0; R51S > R52S >0; R62S > R61S >0; wherein R21S is a radius of curvature of a second object surface of the first lens; R22S is a radius of curvature of the second image-side surface of the first lens; R31S is the radius of curvature of the third object-side surface of the second lens; R32S is a radius of curvature of the third image-side surface of the second lens; R41S is the radius of curvature of the fourth object-side surface of the second lens; R42S is a radius of curvature of the fourth image-side surface of the second lens; R51S is a radius of curvature of a fifth object-side surface of the third lens; R52S is a radius of curvature of the fifth image-side surface of the third lens; R61S is a radius of curvature of a sixth object-side surface of the fourth lens; R62S is a radius of curvature of the sixth image-side surface of the fourth lens.
4. A high resolution side-imaging miniature endoscope objective lens set according to claim 1 and wherein: the high-resolution lateral imaging miniature endoscopic microscope objective group meets the following relation:
1.1<Lst/La<1.3;
wherein Lst is a distance on an optical axis from a second object end surface of the first lens to the aperture stop, and La is a distance on an optical axis from a second object end surface of the first lens to a fourth image end surface of the second lens.
5. A high resolution side-imaging miniature endoscope objective lens set according to claim 1 and wherein: the high-resolution lateral imaging miniature endoscopic microscope objective group meets the following relation: 1.2< La/f <2.1;
wherein La is the distance from the second end surface of the first lens to the fourth end surface of the second lens on the optical axis, and f is the effective focal length of the miniature endoscopic microscope objective group for high-resolution lateral imaging.
6. A high resolution side-imaging miniature endoscope objective lens set according to claim 1 and wherein: the high-resolution lateral imaging miniature endoscopic microscope objective group meets the following relation:
0.2<f b /f<0.4;
wherein f b And f is the effective focal length of the miniature endoscopic microscope objective group for high-resolution lateral imaging.
7. A probe, characterized in that: the miniature endoscopic microscope objective lens comprises a lens cone and a protection gasket, wherein the miniature endoscopic microscope objective lens group for high-resolution lateral imaging is arranged in the lens cone, a light inlet is formed in the side face of the front end of the lens cone, the light inlet is positioned on the surface of the first object end of the first prism, and the protection gasket is arranged at the front end of the lens cone.
8. A probe as in claim 7 wherein: the lens barrel is internally provided with a plurality of space rings and an optical fiber bundle for imaging, the optical fiber bundle is positioned at the rear end of the fourth lens, the space rings comprise a first space ring positioned between the first lens and the second lens, a second space ring positioned between the second lens and the third lens, a third space ring positioned between the third lens and the fourth lens and a fourth space ring positioned between the fourth lens and the optical fiber bundle.
9. A probe as in claim 7 wherein: and the side wall of the lens barrel is provided with an observation hole which is convenient for determining the position of the end face of the optical fiber during assembly.
10. A probe as in claim 9, wherein: the number of the observation holes is 2, and the two observation holes are positioned at opposite positions on the side wall of the lens cone.
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