CN112754726A

CN112754726A - Automatic experimental animal drug delivery device based on big data

Info

Publication number: CN112754726A
Application number: CN202110043074.3A
Authority: CN
Inventors: 李晶; 李玲玲; 李欣欣; 于海波; 李雨轩
Original assignee: Jiamusi University
Current assignee: Jiamusi University
Priority date: 2021-01-13
Filing date: 2021-01-13
Publication date: 2021-05-07

Abstract

The invention discloses an experimental animal automatic drug delivery device based on big data, and belongs to the field of medical instruments for animal experiments. The fixed plate is fixedly connected to the bottom plate through the upright post, the connecting post is sleeved on the upright post, the lower end of the connecting post is fixedly connected with a first rotating plate, the first rotating plate is rotatably connected to the working groove, the upper end of the connecting post is fixedly connected with a second rotating plate, the output shaft of the motor is in transmission connection with a transmission mechanism, and the transmission mechanism is in transmission connection with the rotating device; the first rotating plate is provided with a clamping groove, the second rotating plate is provided with a connecting device corresponding to the clamping groove, the lower end of the fixed plate is fixedly connected with an introduction lug, the introduction lug is provided with a first connecting hole, the output end of the anesthesia jar is communicated and connected to the first connecting hole through an anesthesia tube, when the connecting device is in a second working state, the connecting device is positioned at the lower end of the introduction lug, and the connecting device is communicated with the first connecting hole and a connecting passage of the accommodating device; can continuously operate, has high efficiency, realizes the anesthesia of experimental animals in small batches, and saves manpower.

Description

Automatic experimental animal drug delivery device based on big data

Technical Field

The invention relates to the field of medical instruments for animal experiments, in particular to an automatic drug delivery device for experimental animals based on big data.

Background

In the medical animal experiment, veterinary medicine and pet medical industry, animals are often subjected to anesthesia treatment. The current methods of anesthesia for animals are mainly injection anesthesia and inhalation anesthesia.

Injection of anaesthesia is the intravenous, intramuscular or intraperitoneal injection of an anaesthetic to bring the animal into anaesthesia. Injection type anesthesia has relatively strict control on the dosage of anesthesia, has relatively high operation difficulty, often causes the condition of animal death caused by poor anesthesia effect or excessive anesthesia, can be cleared in vivo after the anesthesia drug is metabolized by the liver and the kidney, has certain side effect on the liver and the kidney, has influence on the experimental result, and has relatively long recovery time of the anesthetized animal; inhalation anesthesia means that an anesthetic enters into blood after entering into an alveolus through breathing, the concentration of the anesthetic in the blood and the inhalation concentration are balanced to maintain an anesthesia state, after the inhalation of the anesthetic is stopped, the anesthetic in the blood is exhaled out of a body through the alveolus, metabolism in the body is basically not needed, the anesthetic is cleared quickly, damage to an internal organ is small, and the influence on an experimental result is small. .

Need carry out the anesthesia to the animal during the experiment among the prior art, adopt the supplementary fixed animal of equipment usually, and carry out the anesthesia operation, because the animal is in the waking state before the anesthesia, and new environment makes the animal be in the alert state easily, receive the frightening easily, need slowly be close to the animal and adopt special fixed gimmick to snatch when anaesthetizing the animal, the removal that needs supplementary fixing device usually or directly restrict the animal with the hand after snatching, and snatch the posture and standardize or the animal receives the frightening, the experimenter is bitten easily, the wound is infected easily, consequently, need carry out a large amount of experimental standardization teaching before the experiment, it is very time-consuming, for improving teaching efficiency, be convenient for the concentrated anesthesia of small batch experimental animal, improve teaching efficiency, the automatic device of dosing of experimental animal based on big data is.

Disclosure of Invention

The invention provides an automatic drug delivery device for experimental animals based on big data, which can solve the problems of low efficiency of an anesthesia mode and inconvenience for batch anesthesia in the prior art.

The utility model provides an automatic device of dosing of experimental animals based on big data, includes base, rotating device, connecting device, accommodate device, motor, anesthesia jar and drive mechanism, wherein:

the base comprises a bottom plate, the bottom plate is provided with a working groove, a feeding groove and a discharging groove, and the feeding groove and the discharging groove are communicated and connected to the working groove;

the rotating device comprises a first rotating plate, a connecting column, a second rotating plate and a fixed plate, the fixed plate is fixedly connected to the bottom plate through an upright column, the connecting column is sleeved on the upright column, the lower end of the connecting column is fixedly connected with the first rotating plate, the first rotating plate is rotatably connected to the working groove, the upper end of the connecting column is fixedly connected with the second rotating plate, the anesthesia tank and the motor are fixedly connected to the fixed plate, an output shaft of the motor is in transmission connection with an input end of the transmission mechanism, and an output end of the transmission mechanism is in transmission connection with the rotating device;

the utility model discloses an anesthesia jar, including first commentaries on classics board, draw-in groove, holding device, second commentaries on classics board corresponds the position of draw-in groove is provided with connecting device, the leading-in lug of lower extreme fixedly connected with of fixed plate, first connecting hole has been seted up to leading-in lug, anesthesia jar's output through anesthesia pipe through-connection to first connecting hole, anesthesia pipe is equipped with the control valve, control valve signal connection to controller, connecting device includes first operating condition, second operating condition and third operating condition at least, wherein:

when the connecting device is in a first working state, the accommodating device corresponding to the connecting device is positioned at the joint of the feed chute and the clamping groove, and the upper end of the connecting device is far away from the guide-in bump;

when the connecting device is in a second working state, the connecting device is positioned at the lower end of the guide-in lug and is communicated with the first connecting hole and the connecting passage of the accommodating device;

when the connecting device is in the third working state, the accommodating device corresponding to the connecting device is positioned at the joint of the discharge chute and the clamping groove, and the upper end of the connecting device is far away from the guiding-in bump.

Further, the guiding-in bump further comprises a first slider and a first limiting block, the first limiting block is fixedly connected in the first connecting hole, the first slider is slidably connected to the first limiting block, the first slider is in dynamic sealing connection with the first limiting block, the first slider is provided with a first vent hole, the side wall of the first slider is provided with a first connecting hole, and the first connecting hole is connected to the first vent hole in a penetrating manner;

when the connecting device is in a first working state or a third working state, the first communicating hole is positioned below the upper end of the first limiting block, and the connecting passage of the anesthetic tube and the first communicating hole is disconnected;

when the connecting device is in the second working state, the first communicating hole is positioned above the upper end of the first limiting block, and the anesthetic tube is communicated with the connecting passage of the first communicating hole.

Furthermore, the connecting device comprises a first slide bar, a connector, a second spring, a second slide bar and a compression spring, the first slide bar is slidably connected to the second rotating plate, the upper end of the first slide bar is fixedly connected with the connector, one end of the second spring is fixedly connected to the connector, the other end of the second spring is fixedly connected to the second rotating plate, the connector is provided with a second connecting hole, the first slide bar is provided with a second vent hole, the second vent hole is communicated with the second connecting hole, the second vent hole is slidably connected with the second slide bar, the second slide bar is provided with a second communicating hole, the second communicating hole is communicated with the second vent hole, one end of the compression spring is fixedly connected to the second slide bar, the other end of the compression spring is fixedly connected to the inner side wall of the second vent hole, and the lower end of the second slide bar is also fixedly connected with a second connecting groove, the second connecting groove may be connected to the accommodating means.

Further, drive mechanism includes wheel groove dish, driver plate and sleeve, the upper end fixed connection of second commentaries on classics board the sleeve, telescopic upper end fixed connection have wheel groove dish, the fixed plate rotationally is connected with the driver plate, the motor passes through the reduction gears transmission and is connected to the driver plate, the driver plate with wheel groove dish cooperation forms intermittent type mechanism.

Further, the accommodating device comprises an accommodating shell, a cover plate and a cover cap, the upper end of the accommodating shell is connected with the cover plate in a sealing fit manner, the cover plate is provided with a rotating rod, the lower end of the rotating rod penetrates through the cover plate, the lower end of the rotating rod is provided with a ventilation cavity, the side wall of the rotating rod is provided with a connecting cavity, the connecting cavity is connected with the ventilation cavity in a penetrating manner, the upper end of the rotating rod is sleeved with the cover cap, the upper end of the cover cap is provided with a third ventilation hole, the lower end of the cover cap is provided with a third connecting hole, the third ventilation hole is connected with the third connecting hole in a penetrating manner, the side wall of the third connecting hole is fixedly connected with a third limiting block, the third limiting block is provided with a clamping groove, the upper end of the rotating rod is fixedly connected with a clamping block, the clamping groove is matched with the clamping block, the other end of the sixth spring is fixedly connected to the third limiting block, and the sixth spring is in a compressed state in a normal state;

when the connecting device is in a first working state or a third working state, the connecting device is separated from the cap, the clamping block is positioned in the clamping groove, the lower end of the clamping block is in sealing fit with the bottom end of the clamping groove, and the connecting passage of the connecting cavity and the third vent hole is disconnected;

when the connecting device is located at the second working state, the connecting device is connected to the third vent hole in a penetrating mode, the lower end of the clamping block is separated from the bottom end of the clamping groove, and the connecting cavity is communicated with a connecting passage of the third vent hole.

Furthermore, the containing device further comprises a clamping device, the rotating rod is rotatably connected to the cover plate, the rotating rod is in dynamic sealing connection with the cover plate, the lower end of the rotating rod is fixedly connected with a second gear, the lower end of the cover plate is provided with a cover plate groove, two opposite side walls of the cover plate groove are slidably connected with a third rack, a connecting block is fixedly connected to the third rack and slidably connected to the cover plate groove, an adjusting rod is rotatably connected to the connecting block, two clamping seats are slidably connected to the connecting block, clamping rods are fixedly connected to the clamping seats, the adjusting rod is a bidirectional screw rod, the two clamping seats are respectively in threaded connection with two opposite sides of the adjusting rod in threaded rotation direction, one end of the adjusting rod is fixedly connected with a rotating handle, and one end of the connecting block, which is far away from the second gear, is fixedly connected with one end of a fifth spring, the other end of the fifth spring is fixedly connected to the inner side of the cover plate groove.

Further, the block fixedly connected with handle, apron upper end fixedly connected with borrow power piece.

Furthermore, the accommodating outer shell further comprises an accommodating inner shell and a sliding plate, the accommodating inner shell is slidably connected to the inner side wall of the accommodating outer shell, the bottom of the accommodating inner shell is fixedly connected with one end of a fourth spring, the other end of the fourth spring is fixedly connected to the bottom of the accommodating outer shell, a first accommodating groove is formed in the side wall of the accommodating outer shell, the sliding plate is slidably connected to the first accommodating groove, the first accommodating groove is rotatably connected with the first gear, one end of the sliding plate, close to the first gear, is fixedly connected with a first rack, the outer side of the accommodating inner shell is fixedly connected with a second rack, and the first rack and the second rack are both meshed with the first gear;

the second rotating plate is fixedly connected with a height sensor, the fixing plate is fixedly connected with a receiver, the height sensor is an ultrasonic sensor, the height sensor is connected to the controller in a linear mode, the receiver can receive signals of the height sensor, and the receiver is connected to the controller in a signal mode.

Further, the outside fixedly connected with second wedge of apron, fixedly connected with sealing flange on the inside wall that holds the inner shell, lead-in groove, sliding tray and seal groove have still been seted up on the inside wall that holds the inner shell, the upper end through connection of lead-in groove to the upper end that holds the inner shell, the lower extreme through connection of lead-in groove to the one end of sliding tray, the other end through connection of sliding tray to the seal groove, the lower extreme through connection of seal groove to the upper end of sealing flange, the upper end slidable of seal groove is connected with first wedge, the upper end fixedly connected with one end of third spring of first wedge, the other end fixed connection of third spring to the upper end of seal groove.

Has the advantages that: the motor passes through drive mechanism and drives the rotating device rotation, the relative position of second commentaries on classics board and fixed plate changes when rotating device rotates, when first commentaries on classics board rotates the below that the container device rotated to leading-in flange, leading-in flange pushes down connecting device, intercommunication anesthesia pipe and container's connecting channel, the quantity of opening and shutting time control anesthetic through controller control solenoid valve, drive the container device and rotate when the blown down tank when first board that changes one by one and take out, can continuously operate, high efficiency, in order to realize the anesthesia of small batch experimental animals, practice thrift the manpower.

Drawings

FIG. 1 is a schematic axial side structure diagram of a big data-based automatic drug delivery device for experimental animals according to the present invention;

FIG. 2 is a schematic side view of the shaft of FIG. 1 with the receiver removed;

FIG. 3 is a front view of a big data-based automatic drug delivery device for laboratory animals according to the present invention;

FIG. 4 is a top view of a big data-based automatic drug delivery device for laboratory animals according to the present invention;

FIG. 5 is a schematic cross-sectional view taken along line A-A of FIG. 4;

FIG. 6 is an enlarged view of a portion of the structure at B in FIG. 5;

FIG. 7 is an enlarged view of a portion of the structure at C in FIG. 5;

FIG. 8 is a schematic axial side structure view of a holding device of a big data-based laboratory animal automatic drug delivery device provided by the invention;

FIG. 9 is a top view of a holding device of the big data based laboratory animal automatic drug delivery device provided by the invention;

FIG. 10 is a schematic cross-sectional view taken at D-D in FIG. 9;

FIG. 11 is an enlarged view of a portion of the structure at E in FIG. 10;

FIG. 12 is a schematic axial side view of the cover plate of FIG. 8;

fig. 13 is a schematic axial side structure diagram of a transmission device of an experimental animal automatic drug delivery device based on big data provided by the invention.

Description of reference numerals:

1-a base, 11-a bottom plate, 12-a discharge chute, 13-a feed chute, 14-a working chute, 2-a rotating device, 21-a first rotating plate, 211-a clamping groove, 22-a connecting column, 23-a second rotating plate, 24-a fixing plate, 241-a lead-in projection, 242-a first connecting hole, 243-a first slider, 244-a first vent hole, 245-a first connecting hole, 246-a first stopper, 3-a connecting device, 31-a first sliding rod, 311-a second vent hole, 312-a second stopper, 32-a connector, 321-a second connecting hole, 33-a second spring, 34-a second sliding rod, 341-a second connecting hole, 342-a second connecting groove, 343-a compression spring, 4-a containing device, 41-accommodating outer shell, 411-first accommodating groove, 412-first gear, 413-fourth spring, 42-accommodating inner shell, 421-sealing flange, 422-introducing groove, 423-sliding groove, 424-sealing groove, 425-first wedge block, 426-third spring, 427-second rack, 43-sliding plate, 431-first rack, 44-cover plate, 441-borrowing block, 442-second wedge block, 443-cover plate groove, 444-fifth spring, 45-cover cap, 451-handle, 452-third vent hole, 453-third connecting hole, 454-third limiting block, 455-sixth spring, 48-clamping device, 481-rotating rod, 482-second gear, 483-third rack, 484-connecting block, 485-clamping seat, 486-adjusting rod, 487-clamping rod, 488-rotating handle, 5-motor, 6-anesthesia can, 61-anesthesia tube, 62-control valve, 63-controller, 7-receiver, 8-height sensor, 9-transmission mechanism, 91-wheel groove disc, 92-drive plate and 93-sleeve.

Detailed Description

An embodiment of the present invention will be described in detail below with reference to the accompanying drawings, but it should be understood that the scope of the present invention is not limited to the embodiment.

Specific example 1:

as shown in fig. 1 to 13, the experimental animal automatic drug delivery device based on big data provided by the embodiment of the present invention includes a base 1, a rotating device 2, a connecting device 3, a containing device 4, a motor 5, an anesthetic tank 6 and a transmission mechanism 9, wherein:

the base 1 comprises a bottom plate 11, the bottom plate 11 is provided with a working groove 14, a feeding groove 13 and a discharging groove 12, and the feeding groove 13 and the discharging groove 12 are connected to the working groove 14 in a penetrating manner;

the rotating device 2 comprises a first rotating plate 21, a connecting column 22, a second rotating plate 23 and a fixing plate 24, the fixing plate 24 is fixedly connected to the bottom plate 11 through an upright column, the connecting column 22 is sleeved to the upright column, the lower end of the connecting column 22 is fixedly connected with the first rotating plate 21, the first rotating plate 21 is rotatably connected to the working groove 14, the upper end of the connecting column 22 is fixedly connected with the second rotating plate 23, the anesthesia tank 6 and the motor 5 are fixedly connected to the fixing plate 24, the output shaft of the motor 5 is in transmission connection with the input end of the transmission mechanism 9, and the output end of the transmission mechanism 9 is in transmission connection with the;

the draw-in groove 211 has been seted up on first commentaries on classics board 21, draw-in groove 211 is used for joint accommodate device 4, accommodate device 4 is used for fixed experimental animals, the position that second commentaries on classics board 23 corresponds draw-in groove 211 is provided with connecting device 3, the leading-in lug 241 of the lower extreme fixedly connected with of fixed plate 24, first connecting hole 242 has been seted up to leading-in lug 241, anesthesia jar 6's output is through anesthesia pipe 61 through-connection to first connecting hole 242, anesthesia pipe 61 is equipped with

control valve

62, 62 signal connection of control valve to controller 63, connecting device 3 includes first operating condition at least, second operating condition and third operating condition, wherein:

when the connecting device 3 is in the first working state, the accommodating device 4 corresponding to the connecting device 3 is located at the joint of the feeding chute 13 and the clamping groove 211, and the upper end of the connecting device 3 is far away from the guiding-in bump 241;

when the connecting device 3 is in the second working state, the connecting device 3 is located at the lower end of the guiding-in projection 241, and the connecting device 3 is communicated with the connecting passage of the first connecting hole 242 and the accommodating device 4;

when the connecting device 3 is in the third operating state, the accommodating device 4 corresponding to the connecting device 3 is located at the joint of the discharging chute 12 and the clamping groove 211, and the upper end of the connecting device 3 is far away from the guiding-in projection 241.

The guiding-in protrusion 241 further includes a first slider 243 and a first stopper 246, the first stopper 246 is fixedly connected in the first connecting hole 242, the first slider 243 is slidably connected to the first stopper 246, the first slider 243 is movably and hermetically connected with the first stopper 246, the first slider 243 is provided with a first vent 244, a side wall of the first slider 243 is provided with a first connecting hole 245, and the first connecting hole 245 is connected to the first vent 244 in a penetrating manner;

when the connecting device 3 is in the first working state or the third working state, the first communicating hole 245 is positioned below the upper end of the first limiting block 246, and the connecting passage of the anesthetic tube 61 and the first communicating hole 245 is disconnected;

when the connecting device 3 is in the second working state, the first communicating hole 245 is located above the upper end of the first stopper 246, and the anesthetic tube 61 is communicated with the communicating passage of the first communicating hole 245.

The connecting device 3 comprises a first sliding rod 31, a connecting head 32, a second spring 33, a second sliding rod 34 and a compression spring 343, the first sliding rod 31 is slidably connected to the second rotating plate 23, the upper end of the first sliding rod 31 is fixedly connected with the connecting head 32, one end of the second spring 33 is fixedly connected to the connecting head 32, the other end is fixedly connected to the second rotating plate 23, the connecting head 32 is provided with a second connecting hole 321, the first sliding rod 31 is provided with a second vent hole 311, the second vent hole 311 is connected to the second connecting hole 321 in a penetrating manner, the second vent hole 311 is slidably connected with the second sliding rod 34, the second sliding rod 34 is provided with a second communicating hole 341, the second communicating hole 341 is connected to the second vent hole 311 in a penetrating manner, one end of the compression spring 343 is fixedly connected to the second sliding rod 34, the other end is fixedly connected to the inner side wall of the second, the second connecting groove 342 may connect the accommodating means 4.

The transmission mechanism 9 comprises a wheel groove disc 91, a drive plate 92 and a sleeve 93, the upper end of the second rotating plate 23 is fixedly connected with the sleeve 93, the upper end of the sleeve 93 is fixedly connected with the wheel groove disc 91, the fixed plate 24 is rotatably connected with the drive plate 92, the motor 5 is in transmission connection with the drive plate 92 through a speed reducing mechanism, and the drive plate 92 and the wheel groove disc 91 are matched to form an intermittent mechanism.

When the anesthesia tube is used, the accommodating device 4 is loaded into the clamping groove 211 through the feeding groove 13, the motor 5 is started, the motor 5 drives the driving plate 92 to rotate, the driving plate 92 drives the wheel groove disc 91 to rotate intermittently, the wheel groove disc 91 drives the second rotating plate 23, the connecting column 22 and the first rotating plate 21 to rotate intermittently, the first rotating plate 21 drives the accommodating device 4 to rotate to the position below the guiding-in bump 241, the slope formed on the lower end face of the guiding-in bump 241 presses the first sliding rod 31 downwards through the hemispherical connector 32, the second sliding rod 34 contacts the accommodating device 4 and is connected to the inside of the accommodating device 4 in a penetrating way, at the moment, the second sliding rod 34 provides flexible pressure through the compression spring 343 and provides pressure for the accommodating device 4 and the first sliding block 243, the first sliding block 243 overcomes gravity to move upwards under the pressure effect, the first vent hole 244 is connected to the second connecting hole 321 in a penetrating way, the first connecting hole 242, at this time, the controller 63 controls the opening and closing of the control valve 62 to input the anesthetic agent into the accommodating device 4, so that the small animal in the accommodating device 4 inhales the anesthetic agent to achieve anesthesia, the motor 5 continues to rotate, and similarly, the accommodating device 4 is driven to leave the position below the introducing projection 241, the first slide bar 31 returns to the original position by overcoming the gravity under the action of the second spring 33, the second slide bar 34 is driven to move upwards, so that the second slide bar 34 leaves the accommodating device 4, which is convenient for taking out the subsequent accommodating device 4, when the connector 32 leaves the first slide bar 243, the first slide bar 243 moves downwards under the action of gravity, the first connection hole 242 is positioned below the upper end of the first limiting block 246, the first connection hole 242 is disconnected with the connection passage of the anesthetic tube 61, the escape of the anesthetic agent is reduced, and the loss;

when the motor 5 continues to rotate, the accommodating device 4 is driven to enter the discharge chute 12, and the accommodating device 4 can be taken out along the discharge chute 12.

Specific example 2:

in embodiment 1, because the requirement of the amount of anesthetic aerosol required by the small animals with different weights is different, in order to improve the anesthetic effect, and the device can adjust the amount of anesthetic aerosol according to the weights of the small animals, as shown in fig. 1 to 13, in this embodiment, the accommodating device 4 includes an accommodating casing 41, a cover plate 44, and a cap 45, the upper end of the accommodating casing 41 is connected with the cover plate 44 in a sealing and fitting manner, the cover plate 44 is provided with a rotating rod 481, the lower end of the rotating rod 481 penetrates through the cover plate 44, the lower end of the rotating rod 481 is provided with a ventilation cavity, the side wall of the rotating rod 481 is provided with a connecting cavity, the connecting cavity is connected to the ventilation cavity in a penetrating manner, the upper end of the rotating rod 481 is sleeved with the cap 45, the upper end of the cap 45 is provided with a third vent 452, the lower end of the cap 45 is provided with a third connecting hole 453, the third vent 452 is connected to the third connecting hole, a clamping groove is formed in the third limiting block 454, a clamping block is fixedly connected to the upper end of the rotating rod 481, the clamping groove is matched with the clamping block, one end of a sixth spring 455 is fixedly connected to the cover plate 44, the other end of the sixth spring 455 is fixedly connected to the third limiting block 454, and the sixth spring 455 is in a compressed state in a normal state;

when the connecting device 3 is in the first working state or the third working state, the connecting device 3 is separated from the cap 45, the clamping block is positioned in the clamping groove, the lower end of the clamping block is in sealing fit with the bottom end of the clamping groove, and the connecting passage of the connecting cavity and the third vent hole 452 is disconnected;

when the connecting device 3 is in the second working state, the connecting device 3 is connected to the third vent hole 452 in a penetrating manner, the lower end of the clamping block is separated from the bottom end of the clamping groove, and the connecting cavity is communicated with the connecting passage of the third vent hole 452;

the cap 45 is fixedly connected with a handle 451, and the upper end of the cover plate 44 is fixedly connected with a force-borrowing block 441.

The accommodating outer shell 41 further comprises an accommodating inner shell 42 and a sliding plate 43, the accommodating inner shell 42 is slidably connected to the inner side wall of the accommodating outer shell 41, the bottom of the accommodating inner shell 42 is fixedly connected with one end of a fourth spring 413, the other end of the fourth spring 413 is fixedly connected to the bottom of the accommodating outer shell 41, a first accommodating groove 411 is formed in the side wall of the accommodating outer shell 41, the sliding plate 43 is slidably connected to the first accommodating groove 411, a first gear 412 is rotatably connected to the first accommodating groove 411, a first rack 431 is fixedly connected to one end of the sliding plate 43 close to the first gear 412, a second rack 427 is fixedly connected to the outer side of the accommodating inner shell 42, and the first rack 431 and the second rack 427 are both meshed with;

the second rotating plate 23 is fixedly connected with a height sensor 8, the fixing plate 24 is fixedly connected with a receiver 7, the height sensor 8 is an ultrasonic sensor, the height sensor 8 is connected to the controller 63 in a linear mode, the receiver 7 can receive signals of the height sensor 8, and the receiver 7 is connected to the controller 63 in a signal mode.

The outer side of the cover plate 44 is fixedly connected with a second wedge block 442, the inner side wall of the accommodating inner shell 42 is fixedly connected with a sealing flange 421, the inner side wall of the accommodating inner shell 42 is further provided with an introduction groove 422, a sliding groove 423 and a sealing groove 424, the upper end of the introduction groove 422 is connected to the upper end of the accommodating inner shell 42 in a penetrating manner, the lower end of the introduction groove 422 is connected to one end of the sliding groove 423 in a penetrating manner, the other end of the sliding groove 423 is connected to the sealing groove 424 in a penetrating manner, the lower end of the sealing groove 424 is connected to the upper end of the sealing flange 421 in a penetrating manner, the upper end of the sealing groove 424 is slidably connected with a first wedge block 425, the upper end of the first wedge.

Before use, a small animal is placed in the inner accommodating shell 42, the first wedge block 425 of the cover plate 44 slides into the sliding groove 423 along the introduction groove 422 and slides into the sealing groove 424 along the sliding groove 423, when the first wedge block 425 slides into the sealing groove 424, the first wedge block 425 jacks up the second wedge block 442 through a wedge surface and slides into the sealing groove 424, at the moment, the second wedge block 442 is pressed downwards to provide pressure for the first wedge block 425, the sealing effect is improved, and the cover plate 44 is matched with the sealing flange 421 to realize sealing;

when the device is used, after a small animal is placed in the containing inner shell 42, the containing inner shell 42 moves downwards due to the fact that the fourth spring 413 is pressed downwards by gravity, the first gear 412 is driven to rotate by the second rack 427, the first gear 412 drives the first rack 431 to move upwards, the sliding plate 43 rises to different heights according to different weights to serve as a mark, after the containing device 4 is placed in the clamping groove 211, the corresponding height sensor 8 on the second rotating plate 23 measures the shortest distance, when the containing device 4 rotates to the position below the guiding-in bump 241, the receiver 7 receives and only receives signals from the height sensor 8 right below and sends the signals to the controller 63, and the controller 63 adjusts the opening duration of the control valve 62 through a big data model, so that the adjustment of the dosage of the anesthetic aerosol is realized, the adaptability is improved, the dosage accuracy of the anesthetic aerosol is improved, and the dosage of the anesthetic aerosol is saved;

when the second sliding rod 34 is pressed downwards, the cap 45 is pressed in, under the action of pressure, the sixth spring 455 is compressed, the cap 45 moves downwards, the third vent hole 452 is communicated with the connecting passage of the connecting cavity, so that the anesthetic aerosol is conveniently filled in the accommodating device 4, for the convenience of air pressure balance, the lower end of the accommodating inner shell 42 is provided with a one-way valve, so that the anesthetic aerosol is conveniently and smoothly filled, when the accommodating device 4 leaves the introducing lug 241, the second sliding rod 34 leaves the cap 45, under the action of the sixth spring 455, the cap 45 moves upwards, the clamping block of the rotating rod 481 is in sealing fit with the lower end of the clamping groove, the third vent hole 452 is disconnected with the connecting passage of the connecting cavity, so that the anesthetic aerosol in the accommodating device 4 is prevented from escaping, and an animal can conveniently and fully absorb the anesthetic aerosol.

Specific example 3:

in embodiment 1 or 2, since the animal is easily shocked by a fright when the animal is grabbed, the operator is easily injured, and the animal is easily grabbed and clamped and fixed by the operator, in embodiment 2, as shown in fig. 1 to 13, the accommodating device 4 in this embodiment further includes a clamping device 48, the rotating rod 481 is rotatably connected to the cover plate 44, the rotating rod 481 is movably and hermetically connected to the cover plate 44, the lower end of the rotating rod 481 is fixedly connected with a second gear 482, the lower end of the cover plate 44 is provided with a cover plate 44 groove, two opposite side walls of the cover plate 44 groove are slidably connected with a third rack 483, a connecting block 484 is fixedly connected to the third rack 483, the connecting block 484 is slidably connected to the cover plate 44 groove, an adjusting rod 486 is rotatably connected to the connecting block 484, two clamping seats 485 are slidably connected to the connecting block 484, and a clamping rod 487 is fixedly connected to the, the adjusting rod 486 is a two-way screw rod, the two clamping seats 485 are respectively in threaded connection with two opposite sides of the adjusting rod 486 in the threaded direction, one end of the adjusting rod 486 is fixedly connected with a rotating handle 488, one end, far away from the second gear 482, of the connecting block 484 is fixedly connected with one end of the fifth spring 444, and the other end of the fifth spring 444 is fixedly connected to the inner side of the groove of the cover plate 44.

Before snatching the toy, it drives the regulation pole 486 and rotates to rotate the swing handle 488, adjust the position of pressing from both sides tight seat 485, thereby adapt to the distance of the different kinds of toy limbs, rotate block 45, block 45 drives the joint piece through the joint groove and rotates, the joint piece drives swing rod 481 and second gear 482 and rotates, second gear 482 drives third rack 483 and removes, third rack 483 drives connecting block 484 and removes, thereby it keeps away from each other to drive tight seat 485 and clamp pole 487, borrow power piece 441 cooperation handle 451 and be convenient for rotate, press from both sides the animal four limbs through clamp pole 487 clamp, loosen block 45, press from both sides tightly under the effort of fifth spring 444, be convenient for press from both sides, apron 44 does the hand protector and prevents that the animal from stinging, be convenient for fixed animal, it struggles the influence to the accuracy of heavy volume measurement to reduce the.

The above disclosure is only for a few specific embodiments of the present invention, however, the present invention is not limited to the above embodiments, and any variations that can be made by those skilled in the art are intended to fall within the scope of the present invention.

Claims

1. The utility model provides an automatic device of dosing of experimental animals based on big data, its characterized in that includes base (1), rotating device (2), connecting device (3), accommodate device (4), motor (5), anesthesia jar (6) and drive mechanism (9), wherein:

the base (1) comprises a bottom plate (11), the bottom plate (11) is provided with a working groove (14), a feeding groove (13) and a discharging groove (12), and the feeding groove (13) and the discharging groove (12) are communicated with the working groove (14);

the rotating device (2) comprises a first rotating plate (21), a connecting column (22), a second rotating plate (23) and a fixing plate (24), the fixing plate (24) is fixedly connected to the bottom plate (11) through an upright column, the connecting column (22) is sleeved to the upright column, the lower end of the connecting column (22) is fixedly connected with the first rotating plate (21), the first rotating plate (21) is rotatably connected to the working groove (14), the upper end of the connecting column (22) is fixedly connected with the second rotating plate (23), the fixing plate (24) is fixedly connected with the anesthesia tank (6) and the motor (5), an output shaft of the motor (5) is in transmission connection with an input end of the transmission mechanism (9), and an output end of the transmission mechanism (9) is in transmission connection with the rotating device (2);

seted up draw-in groove (211) on first commentaries on classics board (21), draw-in groove (211) are used for the joint accommodate device (4), accommodate device (4) are used for fixed experimental animals, second commentaries on classics board (23) correspond the position of draw-in groove (211) is provided with connecting device (3), the leading-in lug of lower extreme fixedly connected with (241) of fixed plate (24), first connecting hole (242) have been seted up in leading-in lug (241), the output of anesthesia jar (6) is through-connected to through anesthetic tube (61) first connecting hole (242), anesthetic tube (61) are equipped with control valve (62), control valve (62) signal connection is to controller (63), connecting device (3) include first operating condition, second operating condition and third operating condition at least, wherein:

when the connecting device (3) is in a first working state, the accommodating device (4) corresponding to the connecting device (3) is positioned at the joint of the feeding groove (13) and the clamping groove (211), and the upper end of the connecting device (3) is far away from the guiding-in lug (241);

when the connecting device (3) is in a second working state, the connecting device (3) is positioned at the lower end of the guiding convex block (241), and the connecting device (3) is communicated with the connecting passage of the first connecting hole (242) and the accommodating device (4);

when the connecting device (3) is in the third working state, the accommodating device (4) corresponding to the connecting device (3) is located at the joint of the discharge chute (12) and the clamping groove (211), and the upper end of the connecting device (3) is far away from the guide-in bump (241).

2. The big-data-based automatic drug delivery device for laboratory animals according to claim 1, wherein the introduction lug (241) further comprises a first slider (243) and a first stopper (246), the first stopper (246) is fixedly connected in the first connection hole (242), the first slider (243) is slidably connected to the first stopper (246), the first slider (243) is movably and hermetically connected with the first stopper (246), the first slider (243) is provided with a first vent hole (244), a side wall of the first slider (243) is provided with a first connection hole (245), and the first connection hole (245) is penetratingly connected to the first vent hole (244);

when the connecting device (3) is in the first working state or the third working state, the first communicating hole (245) is positioned below the upper end of the first limiting block (246), and the connecting passage of the anesthetic tube (61) and the first communicating hole (245) is disconnected;

when the connecting device (3) is in the second working state, the first communicating hole (245) is positioned above the upper end of the first limiting block (246), and the anesthesia tube (61) is communicated with the connecting passage of the first communicating hole (245).

3. The big data-based automatic drug delivery device for laboratory animals according to claim 2, wherein said connection device (3) comprises a first slide bar (31), a connector (32), a second spring (33), a second slide bar (34) and a compression spring (343), said first slide bar (31) is slidably connected to said second rotating plate (23), said connector (32) is fixedly connected to the upper end of said first slide bar (31), one end of said second spring (33) is fixedly connected to said connector (32), the other end of said second spring is fixedly connected to said second rotating plate (23), said connector (32) is opened with a second connection hole (321), said first slide bar (31) is opened with a second ventilation hole (311), said second ventilation hole (311) is through-connected to said second connection hole (321), said second ventilation hole (311) is slidably connected to said second slide bar (34), the second sliding rod (34) is provided with a second communication hole (341), the second communication hole (341) is connected to the second ventilation hole (311) in a penetrating manner, one end of the compression spring (343) is fixedly connected to the second sliding rod (34), the other end of the compression spring is fixedly connected to the inner side wall of the second ventilation hole (311), the lower end of the second sliding rod (34) is further fixedly connected with a second connecting groove (342), and the second connecting groove (342) can be connected with the accommodating device (4).

4. The big-data-based automatic drug delivery device for laboratory animals according to claim 1, wherein the transmission mechanism (9) comprises a wheel-slot disc (91), a dial (92) and a sleeve (93), the upper end of the second rotating plate (23) is fixedly connected with the sleeve (93), the upper end of the sleeve (93) is fixedly connected with the wheel-slot disc (91), the fixing plate (24) is rotatably connected with the dial (92), the motor (5) is in transmission connection with the dial (92) through a speed reduction mechanism, and the dial (92) and the wheel-slot disc (91) are matched to form an intermittent mechanism.

5. The big data-based automatic drug delivery device for laboratory animals according to claim 1, wherein said container (4) comprises a container housing (41), a cover plate (44) and a cap (45), said cover plate (44) is connected to the upper end of said container housing (41) in a sealing fit manner, said cover plate (44) is provided with a rotating rod (481), the lower end of said rotating rod (481) penetrates said cover plate (44), the lower end of said rotating rod (481) is provided with a ventilation cavity, the side wall of said rotating rod (481) is provided with a connection cavity, said connection cavity is connected to said ventilation cavity in a penetrating manner, the upper end of said rotating rod (481) is sleeved with said cap (45), the upper end of said cap (45) is provided with a third ventilation hole (452), the lower end of said cap (45) is provided with a third connection hole (453), said third ventilation hole (452) is connected to said third connection hole (453) in a penetrating manner, a third limiting block (454) is fixedly connected to the side wall of the third connecting hole (453), a clamping groove is formed in the third limiting block (454), a clamping block is fixedly connected to the upper end of the rotating rod (481), the clamping groove is matched with the clamping block, one end of a sixth spring (455) is fixedly connected to the cover plate (44), the other end of the sixth spring (455) is fixedly connected to the third limiting block (454), and the sixth spring (455) is in a compressed state in a normal state;

when the connecting device (3) is in a first working state or a third working state, the connecting device (3) is separated from the cover cap (45), the clamping block is located in the clamping groove, the lower end of the clamping block is in sealing fit with the bottom end of the clamping groove, and a connecting passage between the connecting cavity and the third vent hole (452) is disconnected;

when connecting device (3) are located the second operating condition, connecting device (3) through connection to third ventilation hole (452), the lower extreme of joint piece with the bottom in joint groove breaks away from, connect the chamber with the connecting channel intercommunication of third ventilation hole (452).

6. The big data-based automatic drug delivery device for laboratory animals according to claim 5, wherein the receiving device (4) further comprises a clamping device (48), the rotating rod (481) is rotatably connected to the cover plate (44), the rotating rod (481) is movably and hermetically connected with the cover plate (44), the lower end of the rotating rod (481) is fixedly connected with a second gear (482), the lower end of the cover plate (44) is provided with a groove of the cover plate (44), two opposite side walls of the groove of the cover plate (44) are slidably connected with a third rack (483), the third rack (483) is fixedly connected with a connecting block (484), the connecting block (484) is slidably connected to the groove of the cover plate (44), the connecting block (484) is rotatably connected with an adjusting rod (486), and the connecting block (484) is slidably connected with two clamping seats (485), the clamping rod (487) is fixedly connected to the clamping seat (485), the adjusting rod (486) is a bidirectional screw rod, the two clamping seats (485) are respectively in threaded connection with two opposite sides of the adjusting rod (486) in the threaded direction, one end of the adjusting rod (486) is fixedly connected with a rotating handle (488), one end, far away from the second gear (482), of the connecting block (484) is fixedly connected with one end of a fifth spring (444), and the other end of the fifth spring (444) is fixedly connected to the inner side of the groove of the cover plate (44).

7. The automatic big data-based drug delivery device for laboratory animals according to claim 6, wherein the cap (45) is fixedly connected with a handle (451), and the upper end of the cover plate (44) is fixedly connected with a force-borrowing block (441).

8. The big data based automatic drug delivery device for laboratory animals according to claim 7, wherein said outer receiving case (41) further comprises an inner receiving case (42) and a sliding plate (43), said inner receiving case (42) is slidably connected to the inner sidewall of said outer receiving case (41), the bottom of said inner receiving case (42) is fixedly connected with one end of a fourth spring (413), the other end of said fourth spring (413) is fixedly connected to the bottom of said outer receiving case (41), a first receiving groove (411) is opened on the sidewall of said outer receiving case (41), said sliding plate (43) is slidably connected to said first receiving groove (411), said first receiving groove (411) is rotatably connected with said first gear (412), a first rack (431) is fixedly connected to one end of said sliding plate (43) near said first gear (412), a second rack (427) is fixedly connected to the outer side of the accommodating inner shell (42), and the first rack (431) and the second rack (427) are both meshed with the first gear (412);

second commentaries on classics board (23) fixedly connected with height sensor (8), fixed plate (24) fixedly connected with receiver (7), height sensor (8) are ultrasonic sensor, height sensor (8) nature number is connected to controller (63), the signal of height sensor (8) can be accepted in receiver (7), receiver (7) signal connection to controller (63).

9. The big data-based automatic drug delivery device for experimental animals as claimed in claim 8, wherein a second wedge block (442) is fixedly connected to the outer side of the cover plate (44), a sealing flange (421) is fixedly connected to the inner side wall of the inner containing shell (42), an introduction groove (422), a sliding groove (423) and a sealing groove (424) are further formed in the inner side wall of the inner containing shell (42), the upper end of the introduction groove (422) is connected to the upper end of the inner containing shell (42) in a penetrating manner, the lower end of the introduction groove (422) is connected to one end of the sliding groove (423) in a penetrating manner, the other end of the sliding groove (423) is connected to the sealing groove (424) in a penetrating manner, the lower end of the sealing groove (424) is connected to the upper end of the sealing flange (421) in a penetrating manner, and the upper end of the sealing groove (424) is slidably, one end of a third spring (426) is fixedly connected to the upper end of the first wedge-shaped block (425), and the other end of the third spring (426) is fixedly connected to the upper end of the sealing groove (424).