CN112716849A - 一种含有油茶提取物的防皲裂护肤膏霜 - Google Patents
一种含有油茶提取物的防皲裂护肤膏霜 Download PDFInfo
- Publication number
- CN112716849A CN112716849A CN202110047888.4A CN202110047888A CN112716849A CN 112716849 A CN112716849 A CN 112716849A CN 202110047888 A CN202110047888 A CN 202110047888A CN 112716849 A CN112716849 A CN 112716849A
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- China
- Prior art keywords
- camellia oleifera
- oil
- skin
- cream containing
- skin cream
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Abstract
本发明属于日化领域。一种含有油茶提取物的防皲裂护肤膏霜,包括以下组分:油茶果油、油茶花提取物、透明质酸钠/乙酰化透明质酸钠/透明质酸钠交联聚合物/水解透明质酸钠、甘草酸二甲/尿囊素、甜菜碱/海藻糖/泛醇/锁水磁石/木糖醇、德敏舒/红没药醇/神经酰胺、乳化剂、牛油果树脂、环五聚二甲基硅氧烷/聚二甲基硅氧烷、霍霍巴籽油/澳洲坚果籽油/甜扁桃油/椰子油、鲸蜡硬脂醇/花生醇/山俞醇、矿脂以及余量的水。本发明含有油茶提取物的防皲裂护肤膏霜,以油茶果油和结果前期的油茶花提取物作为主要活性物质,可有效提高肌肤含水量和含油脂量,修复肌肤屏障,增强肌肤抵御环境侵害的能力,从而实现了预防和改善皲裂的效果。
Description
技术领域
本发明属于技术领域,具体涉及一种含有油茶提取物的防皲裂护肤膏霜。
背景技术
皮肤皲裂是指皮肤出现干燥和裂痕症状,常发生于经常摩擦、表皮干燥、增厚的部位,例如手足等无皮脂腺、角质层较厚的区域。秋冬季节皮肤皲裂的原因包括以下几点:①皮脂腺分泌减少,油脂挥发快,缺少油脂,肌肤粗糙;②环境中水分含量降低,肌肤失水干燥;③细胞新陈代谢依赖水分,细胞构成需要脂质,缺乏水分和脂质时,细胞屏障能力减弱,抵御环境侵害能力降低,肌肤易老化、角质层脱落,干燥、皲裂甚至因微生物入侵引发炎症。
茶油色清味香,营养丰富,性质稳定耐存储,油茶果油中的不饱和脂肪酸含量高达80-85%,远高于橄榄油、椰子油、豆油、菜籽油等其它植物油,其维生素E含量也比橄榄油高一倍,还富含原儿茶酸(PCA),这是一种适用于护肤品中的天然酚酸。
现有的防皲裂护肤膏霜大多通过添加大量的如矿脂、腊类脂质等固态合成油脂,增加油脂层厚度来实现隔绝的效果。天然植物油脂如橄榄油、乳木果油、澳大利亚坚果油虽然也有类似油茶果油的抗氧化、修护皮肤、抗炎等作用,但因为这些油脂中三油酸甘油酯含量相对低一点,皮肤护理效果略微显的不足。
发明内容
本发明所要解决的技术问题是提供一种含有油茶提取物的防皲裂护肤膏霜,以油茶果油和结果前期的油茶花提取物作为主要活性物质,可有效提高肌肤含水量和含油脂量,修复肌肤屏障,增强肌肤抵御环境侵害的能力,从而实现了预防和改善皲裂的效果。
本发明的技术方案如下:
一种含有油茶提取物的防皲裂护肤膏霜,包括以下按质量百分比计算的组分:油茶果油1-5%、油茶花提取物0.1-3%、透明质酸钠/乙酰化透明质酸钠/透明质酸钠交联聚合物/水解透明质酸钠0.05-3%、增稠剂0.15-1%、PH调节剂0.03-1%、多元醇1-8%、乙二胺四乙酸二钠0.01-0.02%、甘草酸二甲/尿囊素0.01-0.3%、甜菜碱/海藻糖/泛醇/锁水磁石/木糖醇1-3%、德敏舒/红没药醇/神经酰胺0.1-1%、乳化剂2-6%、牛油果树脂1-8%、环五聚二甲基硅氧烷/聚二甲基硅氧烷0.5-4%、霍霍巴籽油/澳洲坚果籽油/甜扁桃油/椰子油0.1-2.5%、鲸蜡硬脂醇/花生醇/山俞醇0.8-4.5%、矿脂0.2-3.5%、氢化椰油甘油酯类0.2-2%、辛酸/癸酸甘油三酯1-5%以及余量的水。
A.油茶果油
所述油茶果油的制备方法,包括以下步骤:
a取成熟油茶果干燥后,经至少三次的蒸炒处理,去壳粉碎,压榨出油,收集油茶饼;
b.在油茶饼加入无机溶剂浸提,过滤取滤液,将步骤a的压榨所得茶油与滤液混合,即得所述油茶果油。
进一步的,述无机溶剂为6号溶剂油或者丁烷。
油茶果油主要成分为三油酸甘油酯(Oleic Acid),其占比高达83.7wt%,高含量的脂肪酸温和无刺激,对酸化有一定的稳定性,同时可使其他功效成分有效融入肌肤,易被人体吸收。油茶花提取液能显著抑制炎症因子,如Nitril Oxide*(ND)和Eotaxin-1的诱导作用,减少环氧合酶(COX-2)的表达,促进胶原蛋白的合成,抑制由重金属混合物引起的氧化应激作用,具有保护皮肤、舒缓抗皱、淡化暗疮、收缩毛孔的功效。
B.油茶花提取物
所述油茶花提取物的制备方法,包括以下步骤:
S1.摘取10-11月的新鲜油茶花,花瓣洗净、晒干、粉碎,加入浓度95%的乙醇水溶液,乙醇水溶液和花瓣的质量比为16-20:1,室温下浸泡1.5-2h;升温至50-60℃,恒温搅拌20-30min,降至室温后过400目滤网取滤液;
S2.所述滤液加水稀释至乙醇浓度低于60%,在80-83℃的温度下蒸馏,蒸馏收集液用其质量28-30倍的水稀释,搅拌10-30min,升温至78-80℃蒸馏去除乙醇,即得油茶花提取物。
油茶花提取物的主要成分为PCA,作为一种天然酚酸,PCA可有效融入皮肤,抗菌、消炎、抗氧化,预防皮肤衰老。
C.透明质酸钠交联聚合物/透明质酸钠/乙酰化透明质酸钠/水解透明质酸钠
透明质酸钠交联聚合物可使水分进入细胞间隙,并与蛋白质结合形成蛋白凝胶,粘结细胞,发挥正常代谢作用,起到保持细胞水分,保护细胞不受病原菌的侵害,加快恢复皮肤组织,提高创口愈合再生能力,减少疤痕,增强免疫力等作用;大分子透明质酸钠可以在肌肤表面形成致密防护膜,长效锁水保湿,软化角质层,促使组织细胞再生,紧致肌肤,其良好的成膜性能可增强皮肤屏障功能,大大减少紫外线对表皮细胞的损伤,并对外界污染物进行有效隔离;乙酰化透明质酸钠,由HA经乙酰化反应得到,乙酰基的引入给HA带来亲脂性,增强了HA对角质层的亲和性和吸附性,提高了HA的保湿性和修复性;既可在皮肤表面减少水分蒸发、增加内部水分蓄积,又能渗透表皮水合软化角质层,修复受损角质细胞,内外同时作用,发挥双重保湿、高效修复的功效,从而改善肌肤干燥、粗糙状态;水解透明质酸钠可快速渗透肌肤内部,深层锁水,肌底养护,对紫外线损伤细胞有显著的修复能力;四重透明质酸钠复配,可构建针对皮肤的不同层次,外层补水,内层锁水,层层保湿,肌肤由内而外水润亮泽;可随时发挥保湿功效,为肌肤源源不断补充水分,提高皮肤内部水分蓄积,使肌肤满水复活,柔软有弹性。
D.环五聚二甲基硅氧烷/聚二甲基硅氧烷交联聚合物
有机硅弹体混合物是高分子量有机硅弹体在环戊甲基硅氧烷中的混合物,可使皮肤干爽,细腻光滑,清爽不油腻。
E.甘草酸二钾
甘草酸二钾可起到类似于肾上腺皮脂激素的作用,温和安全无毒副作用,可抑制皮肤的炎症反应,改善毛细血管扩张,从而改善皮肤红肿状态,有效抗敏消炎。
F.丙烯酰二甲基牛磺酸铵/VP共聚物
丙烯酰二甲基牛磺酸铵/VP共聚物作为悬浮稳定剂可增加体系的粘稠度,提高体系稳定性,与其他组分配合,赋予了组合物清爽的肤感和细腻柔亮的外观。
进一步的,所述增稠剂为黄原胶/汉生胶0.05-0.2%、卡波姆树脂/聚丙烯酸/丙烯酸聚合物/聚丙烯酸C10-30烷醇丙烯酸酯交联聚合物/聚丙烯酸C10-30烷基丙烯酸酯交联聚合物/丙稀酰二甲基牛磺酸铵VP共聚物/羟乙基丙烯酸酯丙稀酰二甲基牛磺酸钠共聚物0.1-0.8%。
进一步的,所述PH调节剂为三乙醇胺/氢氧化钠/氨甲基丙醇。
进一步的,所述多元醇包括丙三醇、甘油聚醚-26、1,3-丁二醇、丙二醇、乙二醇中的至少一种。
进一步的,所述乳化剂包括鲸蜡硬脂基葡糖苷、椰油基葡糖苷、C12-20烷基葡糖苷、山梨坦硬脂酸酯、鲸蜡硬脂醇聚醚-20、硬脂醇聚醚-2、硬脂醇聚醚-21、甘油硬脂酸酯、PEG-100硬脂酸酯、氢化卵磷脂中的至少一种。
进一步的,还包括防腐剂0.1-0.7%,所述防腐剂包括对羟基苯乙酮、尼泊金酯类、氯苯甘醚、苯氧乙醇、苯甲醇中的至少一种。
本发明具有如下有益效果:
1.赋脂:选用天然植物油油茶果油为主要赋脂剂,辅以乳木果油、橄榄油、霍霍巴籽油、甜扁桃油,复配聚二甲基硅氧烷、合成角鲨烯、氢化椰油甘油酯类等合成油脂,使用后油脂在肌肤表面停留时间长,与肌肤融和效果好,可作用于细胞膜表面,深层次的修复细胞,构建肌肤屏障。
2.补水:选用的保湿剂包括透明质酸、甜菜碱、木糖醇类、海藻糖,可有效渗入细胞间隙和细胞基质内,进行深层补水锁水,提高肌肤含水量,长效保湿滋润。
3.增强皮肤屏障:选用的油茶花提取液具有良好的渗透性,可对德敏舒、神经酰胺、红没药醇等组分进行增效,增强产品在抗菌消炎、抗氧化、抗衰老方面的功效,提高细胞的自我修复能力,赋活肌肤,修复肌肤屏障,增强肌肤抵御环境侵害功能。油茶花、果提取物协同,赋脂、补水、增强肌肤屏障,从而达到了预防、改善皲裂的效果。
具体实施方式
下面结合实施例对本发明进行详细的说明,实施例仅是本发明的优选实施方式,不是对本发明的限定。
实施例1
一种含有油茶提取物的防皲裂护肤膏霜,包括以下按质量百分比计算的组分:
A相:黄原胶/汉生胶0.05%、卡波姆树脂/聚丙烯酸/丙烯酸聚合物/聚丙烯酸C10-30烷醇丙烯酸酯交联聚合物/聚丙烯酸C10-30烷基丙烯酸酯交联聚合物/丙稀酰二甲基牛磺酸铵VP共聚物/羟乙基丙烯酸酯丙稀酰二甲基牛磺酸钠共聚物0.1%、透明质酸钠/乙酰化透明质酸钠/透明质酸钠交联聚合物/水解透明质酸钠0.05%、丙三醇1%;
B相:乙二胺四乙酸二钠0.02%、甘草酸二甲/尿囊素0.01%;
C相:鲸蜡硬脂基葡糖苷2%、牛油果树脂1%、鲸蜡硬脂醇/花生醇/山俞醇0.8%、凡士林0.2%、氢化椰油甘油酯类0.2%、环五聚二甲基硅氧烷/聚二甲基硅氧烷0.5%、油茶果油1%、霍霍巴籽油/澳洲坚果籽油/甜扁桃油/椰子油0.1%、辛酸/癸酸甘油三酯1%;
D相:三乙醇胺/氢氧化钠/氨甲基丙醇0.03%、甜菜碱/海藻糖/泛醇/锁水磁石/木糖醇1%、德敏舒/红没药醇/神经酰胺0.1%、油茶花提取物0.1%;
以及余量的水。
实施例2
一种含有油茶提取物的防皲裂护肤膏霜,包括以下按质量百分比计算的组分:
A相:黄原胶/汉生胶0.2%、卡波姆树脂/聚丙烯酸/丙烯酸聚合物/聚丙烯酸C10-30烷醇丙烯酸酯交联聚合物/聚丙烯酸C10-30烷基丙烯酸酯交联聚合物/丙稀酰二甲基牛磺酸铵VP共聚物/羟乙基丙烯酸酯丙稀酰二甲基牛磺酸钠共聚物0.8%、透明质酸钠/乙酰化透明质酸钠/透明质酸钠交联聚合物/水解透明质酸钠3%、甘油聚醚-26/1,3-丁二醇8%;
B相:
乙二胺四乙酸二钠0.02%、甘草酸二甲/尿囊素0.3%;
C相:
椰油基葡糖苷/山梨坦硬脂酸酯6%、牛油果树脂8%、鲸蜡硬脂醇/花生醇/山俞醇4.5%、凡士林3.5%、氢化椰油甘油酯类2%、环五聚二甲基硅氧烷/聚二甲基硅氧烷4%、油茶果油5%、霍霍巴籽油/澳洲坚果籽油/甜扁桃油/椰子油2.5%、辛酸/癸酸甘油三酯5%;
D相:三乙醇胺/氢氧化钠/氨甲基丙醇1%、甜菜碱/海藻糖/泛醇/锁水磁石/木糖醇3%、德敏舒/红没药醇/神经酰胺1%、油茶花提取物3%;
以及余量的水。
实施例3
一种含有油茶提取物的防皲裂护肤膏霜,包括以下按质量百分比计算的组分:
A相:
黄原胶/汉生胶0.1%、卡波姆树脂/聚丙烯酸/丙烯酸聚合物/聚丙烯酸C10-30烷醇丙烯酸酯交联聚合物/聚丙烯酸C10-30烷基丙烯酸酯交联聚合物/丙稀酰二甲基牛磺酸铵VP共聚物/羟乙基丙烯酸酯丙稀酰二甲基牛磺酸钠共聚物0.6%、透明质酸钠/乙酰化透明质酸钠/透明质酸钠交联聚合物/水解透明质酸钠0.2%、乙二醇5%;
B相:
乙二胺四乙酸二钠0.02%、甘草酸二甲/尿囊素0.01-0.3%;
C相:
硬脂酸甘油酯4%、牛油果树脂4%、鲸蜡硬脂醇/花生醇/山俞醇2.5%、凡士林0.2-3.5%、氢化椰油甘油酯类1.1%、环五聚二甲基硅氧烷/聚二甲基硅氧烷2%、油茶果油3%、霍霍巴籽油/澳洲坚果籽油/甜扁桃油/椰子油1.25%、辛酸/癸酸甘油三酯2.5%;
D相:三乙醇胺/氢氧化钠/氨甲基丙醇0.5%、甜菜碱/海藻糖/泛醇/锁水磁石/木糖醇2%、德敏舒/红没药醇/神经酰胺0.5%、油茶花提取物1.5%;
以及余量的水。
实施例4
一种含有油茶提取物的防皲裂护肤膏霜,包括以下按质量百分比计算的组分:
A相:黄原胶/汉生胶0.05%、卡波姆树脂/聚丙烯酸/丙烯酸聚合物/聚丙烯酸C10-30烷醇丙烯酸酯交联聚合物/聚丙烯酸C10-30烷基丙烯酸酯交联聚合物/丙稀酰二甲基牛磺酸铵VP共聚物/羟乙基丙烯酸酯丙稀酰二甲基牛磺酸钠共聚物0.1%、透明质酸钠/乙酰化透明质酸钠/透明质酸钠交联聚合物/水解透明质酸钠0.05%、丙三醇1%;
B相:乙二胺四乙酸二钠0.02%、甘草酸二甲/尿囊素0.01%;
C相:鲸蜡硬脂基葡糖苷2%、牛油果树脂1%、鲸蜡硬脂醇/花生醇/山俞醇0.8%、凡士林0.2%、氢化椰油甘油酯类0.2%、环五聚二甲基硅氧烷/聚二甲基硅氧烷0.5%、油茶果油5%、霍霍巴籽油/澳洲坚果籽油/甜扁桃油/椰子油0.1%、辛酸/癸酸甘油三酯1%;
D相:三乙醇胺/氢氧化钠/氨甲基丙醇0.03%、甜菜碱/海藻糖/泛醇/锁水磁石/木糖醇1%、德敏舒/红没药醇/神经酰胺0.1%、油茶花提取物3%;
以及余量的水。
对比例1
一种含有油茶提取物的防皲裂护肤膏霜,包括以下按质量百分比计算的组分:
A相:黄原胶/汉生胶0.05%、卡波姆树脂/聚丙烯酸/丙烯酸聚合物/聚丙烯酸C10-30烷醇丙烯酸酯交联聚合物/聚丙烯酸C10-30烷基丙烯酸酯交联聚合物/丙稀酰二甲基牛磺酸铵VP共聚物/羟乙基丙烯酸酯丙稀酰二甲基牛磺酸钠共聚物0.1%、透明质酸钠/乙酰化透明质酸钠/透明质酸钠交联聚合物/水解透明质酸钠0.05%、丙三醇1%;
B相:乙二胺四乙酸二钠0.02%、甘草酸二甲/尿囊素0.01%;
C相:鲸蜡硬脂基葡糖苷2%、牛油果树脂1%、鲸蜡硬脂醇/花生醇/山俞醇0.8%、凡士林0.2%、氢化椰油甘油酯类0.2%、环五聚二甲基硅氧烷/聚二甲基硅氧烷0.5%、油茶果油5%、霍霍巴籽油/澳洲坚果籽油/甜扁桃油/椰子油3.1%、辛酸/癸酸甘油三酯1%;
D相:三乙醇胺/氢氧化钠/氨甲基丙醇0.03%、甜菜碱/海藻糖/泛醇/锁水磁石/木糖醇1%、德敏舒/红没药醇/神经酰胺0.1%;
以及余量的水。
对比例2
一种含有油茶提取物的防皲裂护肤膏霜,包括以下按质量百分比计算的组分:
A相:黄原胶/汉生胶0.05%、卡波姆树脂/聚丙烯酸/丙烯酸聚合物/聚丙烯酸C10-30烷醇丙烯酸酯交联聚合物/聚丙烯酸C10-30烷基丙烯酸酯交联聚合物/丙稀酰二甲基牛磺酸铵VP共聚物/羟乙基丙烯酸酯丙稀酰二甲基牛磺酸钠共聚物0.1%、透明质酸钠/乙酰化透明质酸钠/透明质酸钠交联聚合物/水解透明质酸钠0.05%、丙三醇1%;
B相:乙二胺四乙酸二钠0.02%、甘草酸二甲/尿囊素0.01%;
C相:鲸蜡硬脂基葡糖苷2%、牛油果树脂1%、鲸蜡硬脂醇/花生醇/山俞醇0.8%、凡士林0.2%、氢化椰油甘油酯类0.2%、环五聚二甲基硅氧烷/聚二甲基硅氧烷0.5%、霍霍巴籽油/澳洲坚果籽油/甜扁桃油/椰子油5.1%、辛酸/癸酸甘油三酯1%、油茶花提取物3%;
D相:三乙醇胺/氢氧化钠/氨甲基丙醇0.03%、甜菜碱/海藻糖/泛醇/锁水磁石/木糖醇1%、德敏舒/红没药醇/神经酰胺0.1%、油茶花提取物3%;
以及余量的水。
对比例3
一种含有油茶提取物的防皲裂护肤膏霜,包括以下按质量百分比计算的组分:
A相:黄原胶/汉生胶0.05%、卡波姆树脂/聚丙烯酸/丙烯酸聚合物/聚丙烯酸C10-30烷醇丙烯酸酯交联聚合物/聚丙烯酸C10-30烷基丙烯酸酯交联聚合物/丙稀酰二甲基牛磺酸铵VP共聚物/羟乙基丙烯酸酯丙稀酰二甲基牛磺酸钠共聚物0.1%、、丙三醇1%;
B相:乙二胺四乙酸二钠0.02%、甘草酸二甲/尿囊素0.06%;
C相:鲸蜡硬脂基葡糖苷2%、牛油果树脂1%、鲸蜡硬脂醇/花生醇/山俞醇0.8%、凡士林0.2%、氢化椰油甘油酯类0.2%、环五聚二甲基硅氧烷/聚二甲基硅氧烷0.5%、霍霍巴籽油/澳洲坚果籽油/甜扁桃油/椰子油8.1%、辛酸/癸酸甘油三酯1%;
D相:三乙醇胺/氢氧化钠/氨甲基丙醇0.03%、甜菜碱/海藻糖/泛醇/锁水磁石/木糖醇1%、德敏舒/红没药醇/神经酰胺0.1%;
以及余量的水。
本发明防皲裂护肤膏霜实施例和对比例中所用牛油果树脂的制备方法,包括以下步骤:
a取成熟油茶果干燥后,经三次的蒸炒处理,去壳粉碎,压榨出油,收集油茶饼;
b.在油茶饼加入6号溶剂油浸提,6号溶剂油与油茶饼的质量比为10:1过滤取滤液,将步骤a的压榨所得茶油与滤液混合,即得所述油茶果油。
所用油茶花提取物的制备方法,包括以下步骤:
S1.摘取5-6月的新鲜油茶花,花瓣洗净、晒干、粉碎,加入浓度95%的乙醇水溶液,乙醇水溶液和花瓣的质量比为16:1,室温下浸泡2h;升温至50℃,恒温搅拌20min,降至室温后过400目滤网取滤液;
S2.所述滤液加水稀释至乙醇浓度低于60%,在83℃的温度下蒸馏,蒸馏收集液用其质量28倍的水稀释,搅拌30min,升温至78℃蒸馏去除乙醇,即得油茶花提取物。
本发明防皲裂护肤膏霜实施例和对比例的制备方法为:将A相组分混合,搅拌分散至无结团成块状态;加入水和B相组分搅拌均匀,升温至80-85℃,均质30min;将C相中各组分混合升温至82-88℃,搅拌至完全溶解,均质5min,与均质后的AB相混合;ABC相降温至40-45℃,加入D相搅拌15-20min,分散均匀即可。
对本发明防皲裂护肤膏霜4个实施例和3个对比例的功效进行仪器功效评估、人体感官评价两种方法进行功效评估,采用均值分析、变化率分析及T检验进行检测分析,测试方法如下:
(1)任意挑选70个有皮肤皲裂现象的志愿者,每组为10个志愿者,选择足部作为测试部位,测试部位测试前2~3天不能使用任何产品(化妆品或外用药品),1~3小时不能接触。
(2)测试取点:角质层水分含量测试项目、经表皮失水量测试项目、皮肤光泽度测试项目的对照区与样品区应具有随机性,对照区和样品区均应随机且均匀地出现在样本总体左右侧的其中一侧,对照区与样品区的取点应左右对称,确保所有对照区和空白区位置在统计学上达到平衡。筛选入组后,受试者需要统一用清水清洁测试部位,用干的面巾纸擦拭干水分,在符合环境要求的房间内静坐10min,期间不能喝水和饮料。测试部位暴露,呈测试状态放置,保持放松。选取足部两处皲裂部位,分别作为样品区和对照区,测试时间为初始值、一周后、两周后、四周后四个时间点数值。
(3)用Corneometer水分测试探头测试受试者对照区、样品区的角质层水分含量,每个区域平行测定2次,取平均值作为基础角质层水分含量。
(4)用Tewameter水分流失探头测试受试者对照区、样品区的经表皮失水量,每个区域测定3次,取平均值作为基础经表皮失水量。
(5)用Skin-GlossymeterGL200皮肤光泽度测试探头测试受试者对照区、样品区的皮肤光泽度,每个区域测定2次,取平均值作为皮肤光泽度值。
(6)用Cutometer皮肤弹性测试探头测试受试者对照区、样品区的皮肤弹性数值,每个区域测定2次,取平均值作为皮肤弹性数值。
(7)对受试者进行问卷调差,看受试者自我感觉皮肤皲裂效果是否有改善,分别进行评分,0分无改善,10分较大改善。
(8)使用样品:将受试者正常使用身体膏霜的量实施例涂抹于样品区,涂抹至完全吸收,对照区为对比例。
(9)功效测试:从涂抹样品的时间开始计时,于7d、14d和28d分别测定样品区、对照区的角质层水分含量、经表皮失水量、皮肤光泽度,角质层水分含量每个区域平行测定2次,经表皮失水量每个区域测定3次,皮肤光泽度每个区域平行测定2次,皮肤弹性数值每个区域测定2次,皮肤油脂数值每个区域测定2次取平均值作为各指标数值。
(10)各自取平均值作为测试角质层水分含量值、测试经表皮失水量值,皮肤光泽度值,同一个受试者的测试必须使用同一仪器由同一个测试人员完成,两次测量之间应清洁测试探头。
所用仪器如下表所示:
仪器名称 | 型号规格 |
皮肤测试仪 | CKMPA580 |
Corneometer水分测试探头 | CorneometerCM825 |
Tewameter水分流失探头 | TewameterTM300 |
Glossymeter光泽度测试探头 | GlossymeterGL200 |
Cutometer皮肤弹性测试探头 | CutometerMPA580 |
Sebumeter皮肤油脂测试探头 | SebumeterSM815 |
(11)人体感官评价:各受试者从涂抹样品的时间开始计时,对坚实度、挑起性、厚实感、滑感、即时粘感、2min粘感、5min粘感、滋润感(5min)、残留感(5min)、滑感(5min)等指标进行评价,评分介于0-10分,取平均值。
可见,本发明护肤膏霜具有较好的肤感,可以提高皮肤水分和油脂含量,减少短期经表皮平均水分流失率,进行补水赋脂,同时能够改善因失水干燥而引起的皮肤皲裂。
本发明含有油茶提取物的防皲裂护肤膏霜,以油茶果油和结果前期的油茶花提取物作为主要活性物质,可有效提高肌肤含水量和含油脂量,修复肌肤屏障,增强肌肤抵御环境侵害的能力,从而实现了预防和改善皲裂的效果。
Claims (9)
1.一种含有油茶提取物的防皲裂护肤膏霜,其特征在于,包括以下按质量百分比计算的组分:油茶果油1-5%、油茶花提取物0.1-3%、透明质酸钠/乙酰化透明质酸钠/透明质酸钠交联聚合物/水解透明质酸钠0.05-3%、增稠剂0.15-1%、PH调节剂0.03-1%、多元醇1-8%、乙二胺四乙酸二钠0.01-0.02%、甘草酸二甲/尿囊素0.01-0.3%、甜菜碱/海藻糖/泛醇/锁水磁石/木糖醇1-3%、德敏舒/红没药醇/神经酰胺0.1-1%、乳化剂2-6%、牛油果树脂1-8%、环五聚二甲基硅氧烷/聚二甲基硅氧烷0.5-4%、霍霍巴籽油/澳洲坚果籽油/甜扁桃油/椰子油0.1-2.5%、鲸蜡硬脂醇/花生醇/山俞醇0.8-4.5%、矿脂0.2-3.5%、氢化椰油甘油酯类0.2-2%、辛酸/癸酸甘油三酯1-5%以及余量的水。
2.根据权利要求1所述的含有油茶提取物的防皲裂护肤膏霜,其特征在于,所述油茶果油的制备方法,包括以下步骤:
a.取成熟油茶果干燥后,经至少三次的蒸炒处理,去壳粉碎,压榨出油,收集油茶饼;
b.在油茶饼加入无机溶剂浸提,过滤取滤液,将步骤a的压榨所得茶油与滤液混合,即得所述油茶果油。
3.根据权利要求2所述的含有油茶提取物的防皲裂护肤膏霜,其特征在于,所述无机溶剂为6号溶剂油或者丁烷。
4.根据权利要求1所述的含有油茶提取物的防皲裂护肤膏霜,其特征在于,所述油茶花提取物的制备方法,包括以下步骤:
S1.摘取10-12月的新鲜油茶花,花瓣洗净、晒干、粉碎,加入浓度95%的乙醇水溶液,乙醇水溶液和花瓣的质量比为16-20:1,室温下浸泡1.5-2h;升温至50-60℃,恒温搅拌20-30min,降至室温后过400目滤网取滤液;
S2.所述滤液加水稀释至乙醇浓度低于60%,在80-83℃的温度下蒸馏,蒸馏收集液用其质量28-30倍的水稀释,搅拌10-30min,升温至78-80℃蒸馏去除乙醇,即得油茶花提取物。
5.根据权利要求1所述的含有油茶提取物的防皲裂护肤膏霜,其特征在于,所述增稠剂为黄原胶/汉生胶0.05-0.2%、卡波姆树脂/聚丙烯酸/丙烯酸聚合物/聚丙烯酸C10-30烷醇丙烯酸酯交联聚合物/聚丙烯酸C10-30烷基丙烯酸酯交联聚合物/丙稀酰二甲基牛磺酸铵VP共聚物/羟乙基丙烯酸酯丙稀酰二甲基牛磺酸钠共聚物0.1-0.8%。
6.根据权利要求1所述的含有油茶提取物的防皲裂护肤膏霜,其特征在于,所述PH调节剂为三乙醇胺/氢氧化钠/氨甲基丙醇。
7.根据权利要求1所述的含有油茶提取物的防皲裂护肤膏霜,其特征在于,所述多元醇包括丙三醇、甘油聚醚-26、1,3-丁二醇、丙二醇、乙二醇中的至少一种。
8.根据权利要求1所述的含有油茶提取物的防皲裂护肤膏霜,其特征在于,所述乳化剂包括鲸蜡硬脂基葡糖苷、椰油基葡糖苷、C12-20烷基葡糖苷、山梨坦硬脂酸酯、鲸蜡硬脂醇聚醚-20、硬脂醇聚醚-2、硬脂醇聚醚-21、甘油硬脂酸酯、PEG-100硬脂酸酯、氢化卵磷脂中的至少一种。
9.根据权利要求1所述的含有油茶提取物的防皲裂护肤膏霜,其特征在于,还包括防腐剂0.1-0.7%,所述防腐剂包括对羟基苯乙酮、尼泊金酯类、氯苯甘醚、苯氧乙醇、苯甲醇中的至少一种。
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