CN112716661B - Artificial cervical intervertebral joint printed in 3D mode - Google Patents
Artificial cervical intervertebral joint printed in 3D mode Download PDFInfo
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- CN112716661B CN112716661B CN202011533979.0A CN202011533979A CN112716661B CN 112716661 B CN112716661 B CN 112716661B CN 202011533979 A CN202011533979 A CN 202011533979A CN 112716661 B CN112716661 B CN 112716661B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
- A61F2/4405—Joints for the spine, e.g. vertebrae, spinal discs for apophyseal or facet joints, i.e. between adjacent spinous or transverse processes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
- A61F2/30771—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
- A61F2/442—Intervertebral or spinal discs, e.g. resilient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/3094—Designing or manufacturing processes
- A61F2002/30985—Designing or manufacturing processes using three dimensional printing [3DP]
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- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Neurology (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Prostheses (AREA)
Abstract
The embodiment of the invention discloses a 3D-printed artificial cervical intervertebral joint, which comprises an upper cone, a nucleus pulposus-spring structural unit and a lower cone, wherein the nucleus pulposus-spring structural unit comprises a nucleus pulposus body and a medical spring, the nucleus pulposus body comprises an upper spherical surface of the nucleus pulposus body, a nucleus pulposus main body and a nucleus pulposus lower connecting body which are of an integrated structure, a concave surface matched with the upper spherical surface of the nucleus pulposus body is arranged on the bottom surface of the upper cone and is in contact with the upper spherical surface of the nucleus pulposus body, a channel for the movement of the nucleus pulposus lower connecting body is arranged in the lower cone, the medical spring is arranged in the channel and acts on the nucleus pulposus lower connecting body, a spring limiting plate bayonet penetrating into the channel is arranged on the side surface of the lower cone, and a spring limiting clamping plate for limiting the medical spring in a compressed state is inserted in the spring limiting plate bayonet. The invention can solve the problems of prosthesis dislocation after the existing artificial cervical intervertebral disc replacement, difficult installation of the existing artificial cervical intervertebral disc and the like.
Description
Technical Field
The invention relates to the technical field of medical prosthesis and 3D printing, in particular to a 3D printed artificial cervical interbody joint.
Background
Cervical spondylosis takes protrusion of intervertebral disc as a main pathogenic cause, pain can be relieved by massage with light degree, diseased intervertebral disc needs to be removed by operation for more serious cervical spondylosis, and artificial intervertebral disc prosthesis is implanted into the intervertebral of a patient by cervical intervertebral disc replacement; however, artificial intervertebral disc prostheses also have some disadvantages: firstly, the product has complicated structure and single size selection, and for some individuals with larger or smaller vertebrae, the intervertebral height can not be well maintained after the prosthesis is implanted, so that the intervertebral space is too large or too small, the joint mobility is reduced, and finally, the soft tissue ossification is caused; secondly, the product has poor fatigue resistance and abrasion resistance, so that the prosthesis is easy to abrade, most of the prosthesis brackets have metal structures, the biocompatibility of the prosthesis brackets and the original vertebral tissues is extremely poor, the distribution rule of human body biomechanics is easy to damage, and the artificial prosthesis falls off.
And the artificial skeleton printed by 3D can well solve the problems. The 3D printing technology is one of the rapid prototyping technologies, and is a technology for constructing an object by using an adhesive material such as powdered metal or plastic on the basis of a digital model in a layer-by-layer stacking manner, so that many complex structures can be printed. For vertebrae with serious pathological changes, which have bone spurs and even bone necrosis, the requirement for implanting the artificial intervertebral disc prosthesis cannot be met, and at this time, a part of vertebrae of a patient needs to be cut off and replaced by a 3D printed bionic cervical vertebra shoulder joint. The pathological part of the vertebra of the patient is intercepted through the operation, and the bionic vertebra printed by 3D and the designed intervertebral disc are used for replacing, so that the bionic cervical vertebra based on 3D printing can be well combined with the vertebra of the patient, and the individual requirements of all patients can be almost met. The existing artificial cervical intervertebral disc on the market adopts the traditional simplified structure of the human cervical vertebra, the function and the form are single, the shapes of the cervical end plates of each patient are different, the existing standard implant cannot be matched with the physiological parameters of all patients, the artificial intervertebral disc is easy to fall off, the individualized requirement and the requirement of flexible manufacturing are difficult to adapt, in addition, the activity intensity of the existing artificial cervical intervertebral disc is limited, and the success of the operation is difficult to ensure.
Disclosure of Invention
The technical problem to be solved by the embodiment of the invention is to provide a 3D printed artificial cervical intervertebral joint. Can improve the movement strength and firmness of the artificial cervical intervertebral joint and improve the success rate of the operation.
In order to solve the technical problems, an embodiment of the invention provides a 3D-printed artificial cervical intervertebral joint, which comprises an upper cone, a nucleus pulposus-spring structural unit and a lower cone, wherein the nucleus pulposus-spring structural unit comprises a nucleus pulposus body and a medical spring, the nucleus pulposus body comprises an upper spherical surface of the nucleus pulposus body, a nucleus pulposus main body and a lower nucleus pulposus connecting body which are of an integrated structure, a concave surface matched with the upper spherical surface of the nucleus pulposus body is arranged on the bottom surface of the upper cone and is in contact with the upper spherical surface of the nucleus pulposus body, a channel for allowing the lower nucleus pulposus connecting body to move is arranged in the lower cone, the medical spring is arranged in the channel and acts on the lower nucleus pulposus connecting body, a spring limiting plate bayonet penetrating into the channel is arranged on the side surface of the lower cone, and a spring limiting clamping plate for limiting the medical spring in a compressed state is inserted in the spring limiting plate.
Wherein, the nucleus pulposus-spring constitutional unit still includes connector under spring supporter, the spring supporter includes the connector on spliced pole, the fixed disc of spring under the fixed disc of spring, the fixed disc of spring passes through the fixed disc of spring on the connector with connector fixed connection under the nucleus pulposus, the fixed disc of spring under the spliced pole fixed set up in the fixed disc lower surface of spring, the connector fixed set up in under the spring the bottom of passageway, medical spring set up in under the fixed disc of spring between the connector under spliced pole, the spring.
The tail end of the spring limiting clamping plate acts between the spring fixing disc and the nucleus pulposus lower connecting body.
Wherein, the upper surface of the upper cone and the lower surface of the lower cone are provided with irregular cylindrical osteogenic pores.
Wherein, the side edges of the upper cone and the lower cone are provided with positioning perforations matched with the osteotomy of the human body.
Wherein, the shapes of the nucleus pulposus lower connecting body and the channel are both cylinders which are matched with each other.
The embodiment of the invention has the following beneficial effects:
(1) The invention effectively solves the problem of difficult installation in the process of artificial cervical intervertebral joint replacement. When the artificial cervical intervertebral joint replacement operation is carried out, the installation mode of the integrated structure is difficult to install, the operation time is long, and the operation risk is large.
(2) The invention adopts perforation for fixation. Compared with the traditional fixing method of additionally arranging the fixing ears on and under the cervical vertebra shoulder joint, the perforation fixing ensures that the joint of the artificial cervical vertebra shoulder joint and the upper and lower vertebrae is firmer, the stress distribution is more uniform during the movement, and the stress concentration can not be generated.
(3) The present invention is an asymmetric intervertebral disc design. The upper spherical surface 13 of the marrow nucleus body is the upper half part of the intervertebral disc and is a hemispherical surface which is tightly attached to the printed upper vertebra, can realize the twisting and tilting actions with multiple degrees of freedom and has certain elasticity; the nucleus pulposus body 12 is a nucleus pulposus body, has a lateral concave structure, and cannot bulge out of an intervertebral disc due to the extrusion of upper and lower vertebrae in a stress process due to the special structure; the nucleus pulposus lower connecting body 11 is the lower half part of the intervertebral disc and is a cylinder and mainly used for preventing the artificial intervertebral disc from falling off. Therefore, the design of the intervertebral disc not only enables a person to move with multiple degrees of freedom, but also can effectively prevent the intervertebral disc from bulging and falling off.
(4) The upper and lower vertebral bodies are of different sizes. The patient may have more bone necrosis to remove, and may be provided with a medical spring to minimize the removal of the vertebrae.
(5) The bionic cervical vertebra shoulder joint is combined with a 3D printing technology, and the diseased vertebra and intervertebral disc of a patient are replaced by the bionic cervical vertebra shoulder joint printed in a 3D mode, so that the problems of complex structure and unmatched size and model of a vertebral body can be solved to the greatest extent; the upper and lower printed vertebrae have cylindrical pores and are coated with nanometer bone affinity material for loading the factors secreted by vertebrae and better fusing the printed vertebrae with vertebrae.
Drawings
FIG. 1 is a half cross-sectional view of the inventive structure;
FIG. 2 is an isometric view of the upper cone of the present invention;
FIG. 3 is an isometric view of the lower cone of the present invention;
FIG. 4 is an assembly view of the nucleus pulposus-spring structural unit of the invention;
FIG. 5 is a semi-sectional view of the nucleus pulposus-spring structural unit of the invention in a compressed state;
FIG. 6 is a view of the nucleus pulposus-spring structural unit of the invention in a compressed state;
FIG. 7 is a view of the nucleus pulposus-spring structural unit of the invention in an extended state;
fig. 8 is a schematic view of the assembly structure of the present invention.
In the figure: 1 osteogenic pores; 2, an upper cone; 2-1, a concave surface; 2-2, an upper end plate; 3, positioning and perforating; 4, a lower cone; 4-1 nucleus pulposus-spring structure unit movement channel; 4-2 lower end plate; 5, a spring limiting plate bayonet; 6, a spring limiting clamping plate; 7, a lower spring connecting body; 8, a medical spring; 9 spring fixing disc; 9-1 spring fixing disc lower connecting column; 10 spring fixing disc upper connector; 11 a nucleus pulposus lower connector; 12 a nucleus pulposus body; 13 spherical on the nucleus.
Detailed Description
To make the objects, technical solutions and advantages of the present invention more apparent, the present invention will be described in further detail with reference to the accompanying drawings.
The artificial cervical intervertebral joint printed in 3D comprises an upper cone 2, a nucleus pulposus-spring structural unit and a lower cone 4; the nucleus pulposus-spring structural unit comprises a nucleus pulposus body, a spring supporting body, a medical spring 8 and a spring lower connecting body 7; the nucleus pulposus body comprises a nucleus pulposus upper spherical surface 13, a nucleus pulposus main body 12 and a nucleus pulposus lower connecting body 11; the spring support body comprises a spring fixing disc 9, a spring fixing disc lower connecting column 9-1 and a spring fixing disc upper connecting body 10; the lower spring connector 7 is installed at the bottom of the moving channel 4-1.
A motion channel 4-1 is arranged in the lower cone 4, and a spring limiting plate bayonet 5 is arranged on the side surface of the lower cone 4.
An irregular cylindrical osteogenic aperture 1 is provided in the upper surface of the superior vertebra 2 and the inferior surface of the inferior vertebra 4 for receiving an osteogenesis inducing factor.
As the axonometric drawing of last cone 2 shown in fig. 2, last cone 2 is provided with and cuts bone matched with location perforation 3, and location perforation 3 runs through whole last cone, and when combining together fixedly with human cone, the location is more accurate, connects more firmly. Meanwhile, a concave surface 2-1 which is matched with the upper spherical surface 13 of the marrow nucleus body is arranged, the upper spherical surface 13 of the marrow nucleus body is contacted with the concave surface 2-1 in the upper cone body 2 through the spherical surface, and the functions of buffering and dispersing stress are realized in the process of stretching the cervical vertebra.
As shown in fig. 3, the lower cone 4 and the upper cone 2 are asymmetric structural features. As the structural characteristics of different vertebrae of a human body are known, the upper vertebrae and the lower vertebrae have slight structural differences, and in order to realize convenient installation, reduce the surgical risk of the artificial cervical intervertebral joint and improve the operability of the surgery, a channel 4-1 for the movement of the nucleus pulposus-spring structural unit is arranged in the lower vertebrae 4, the arranged movement channel 4-1 is positioned in the central part of the lower vertebrae 4, the shape of the movement channel is a cylindrical shape, so that the nucleus pulposus-spring unit can reduce the friction resistance in the extending process, and a positioning through hole 3 matched with the osteotomy of the human body is arranged, penetrates through the whole lower vertebrae 4, is distributed on one side of the side surface of the lower vertebrae 4, and is a pair.
As can be seen from fig. 4, the nucleus pulposus-spring structure unit comprises a nucleus pulposus upper spherical surface 13, a nucleus pulposus body main body 12, a nucleus pulposus lower connecting body 11, a spring fixing disc 9, a spring fixing disc lower connecting column 9-1, a spring fixing disc upper connecting body 10, a medical spring 8 and a spring lower connecting body 7, wherein the medical spring 8 has high elastic potential energy and high mobility, the upper end of the medical spring 3 is in interference fit with the spring fixing disc lower connecting column 9-1, the lower end of the medical spring 3 is also in interference fit with the spring lower connecting body 7, and the interference fit connection is simple and firm. The nucleus pulposus-spring structure unit mode is adopted, the medical spring 8 is combined with the nucleus pulposus body, the intensity of cervical vertebra movement can be improved, and meanwhile, the high flexibility of the movement of the nucleus pulposus body is improved.
As shown in fig. 5 and 6, before the operation, the artificial cervical intervertebral joint is in a compressed state, the spring limiting clamping plate 6 passes through the bayonet 5 of the spring limiting plate arranged on the lower cone 4 and is blocked on the spring fixing disc 9 to limit the medical spring, so that the nucleus pulposus-spring movable unit 14 is in a compressed state, and the upper cone 2 and the lower vertebra 4 are in a tight gap position. As can be seen from fig. 6, when the operation is performed, the artificial cervical intervertebral joint with the nucleus pulposus-spring structural unit in a compressed state is implanted into the osteotomy space, so that the convenience of the operation is greatly improved, and the complexity of the installation of the artificial cervical intervertebral joint is reduced.
As shown in fig. 6, 7 and 8, in the operation process, the artificial cervical joint which is already installed in the human body osteotomy space is fixed in the human body osteotomy space through the fixing through hole 3 on the side surface of the upper cone 2 and the lower cone 4, then the spring limiting clamping plate 6 is taken out from the spring limiting plate bayonet 5 arranged on the lower vertebra 4, the spring limiting clamping plate 6 is not blocked on the spring fixing disc 9, the medical spring 8 is in an extending state, at the moment, the nucleus pulposus-spring structural unit is lifted in the movement channel 4-1 under the thrust of the medical spring 8, the nucleus pulposus upper spherical core body 13 is in spherical combination with the concave surface 2-1 arranged in the upper cone 2, the medical spring 8 is in the extending state and has certain pretightening force, so that the medical spring 8 is combined with the nucleus pulposus 14, the nucleus pulposus core body 14 is installed in place through the medical spring 8 by means of the movement channel 4-1, the operation process is simplified, and the movement strength and firmness of the nucleus pulposus 14 are enhanced.
The artificial cervical intervertebral joint has the advantages of ingenious structural design and simple manufacture, improves the motion intensity of the cervical vertebra, and increases the motion activity of the cervical vertebra (the motion intensity is enhanced by the spring, and the sphere 13 on the nucleus pulposus body improves the motion range and activity of the cervical vertebra).
The upper vertebra 2 and the lower vertebra 5 are connected with the cervical vertebra of the human body through the positioning perforation 3, the connection mode is simple, and the strength is reliable.
Before the operation, adopt spring limiting plate 6 to be spacing nucleus pulposus-spring constitutional unit at compression state, easy to assemble and simplify the operation step, after artifical cervical intervertebral joint implantation osteotomy space, take out spring limiting clamping plate 6, make the nucleus pulposus body 14 rise to with the inside anastomotic within range of upper cone 2, improved the success nature of operation greatly, improved the intensity and the dynamics of cervical vertebra activity simultaneously.
The invention can be used in the operation treatment of various artificial intervertebral joints, can realize individual requirements by adjusting the 3D printing process aiming at different individual cervical intervertebral discs and cervical vertebra structures, enlarges the application range of the artificial intervertebral joints and brings good news to patients.
While the foregoing is directed to the preferred embodiment of the present invention, it will be understood by those skilled in the art that various changes and modifications may be made without departing from the spirit and scope of the invention.
Claims (4)
1. The utility model provides a joint between artifical cervical vertebra that 3D printed, its characterized in that, includes cone, nucleus pulposus-spring constitutional unit, lower cone, nucleus pulposus-spring constitutional unit includes nucleus pulposus body, medical spring, the nucleus pulposus body includes that the nucleus pulposus body of integrative structure goes up sphere, nucleus pulposus main part, connector under the nucleus pulposus, go up the cone bottom surface be provided with the identical concave surface of sphere on the nucleus pulposus body, both contact through the sphere, cone inside is provided with down is used for supplying the passageway of connector motion under the nucleus pulposus, medical spring set up in the passageway, and act on connector under the nucleus pulposus, the cone side is provided with one down and runs through extremely spring limiting plate bayonet socket in the passageway, nucleus pulposus-spring constitutional unit still includes connector under spring supporter, the spring supporter includes that the spring fixes disc, the connector on the spring fixed disc connector under the disc, the spring fixed disc passes through connector on the spring fixed disc with connector fixed connection under the nucleus pulposus, the spring fixed disc connector is fixed under the spring fixed disc lower, the spring fixed disc connector is equipped with the spring clamping plate under the spring fixed spring clamping plate, the spring fixed spring clamping plate makes the spring clamping plate.
2. The 3D-printed artificial cervical intervertebral joint according to claim 1, wherein the upper surface of the upper cone and the lower surface of the lower cone are provided with irregular cylindrical osteogenic pores.
3. The 3D printed artificial inter-cervical joint according to claim 2, wherein the side edges of the upper cone and the lower cone are provided with positioning perforations which are matched with the osteotomy of the human body.
4. The 3D printed artificial cervical intervertebral joint according to any one of claims 1 to 3, wherein the shape of the sub-nucleus pulposus connector and the shape of the channel are both mutually matched cylinders.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011533979.0A CN112716661B (en) | 2020-12-22 | 2020-12-22 | Artificial cervical intervertebral joint printed in 3D mode |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011533979.0A CN112716661B (en) | 2020-12-22 | 2020-12-22 | Artificial cervical intervertebral joint printed in 3D mode |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN112716661A CN112716661A (en) | 2021-04-30 |
| CN112716661B true CN112716661B (en) | 2022-11-22 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN202011533979.0A Active CN112716661B (en) | 2020-12-22 | 2020-12-22 | Artificial cervical intervertebral joint printed in 3D mode |
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Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1542626B1 (en) * | 2002-08-15 | 2012-09-26 | Synthes GmbH | Controlled artificial intervertebral disc implant |
| NZ550176A (en) * | 2004-04-02 | 2009-09-25 | Synthes Gmbh | Intervertebral disc prosthesis or artificial vertebral body |
| CN101612073B (en) * | 2008-06-23 | 2012-05-09 | 邹德威 | Telescopic artificial intervertebral disc scaffold and artificial intervertebral disc body using same |
| US8353964B2 (en) * | 2010-11-04 | 2013-01-15 | Carpenter Clyde T | Anatomic total disc replacement |
| CN108836579B (en) * | 2018-07-06 | 2023-07-28 | 北京爱康宜诚医疗器材有限公司 | Artificial intervertebral disc prosthesis |
| CN111317597B (en) * | 2020-02-24 | 2022-03-18 | 汕头大学 | 3D printed bionic artificial cervical intervertebral joint |
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2020
- 2020-12-22 CN CN202011533979.0A patent/CN112716661B/en active Active
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| CN112716661A (en) | 2021-04-30 |
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