CN112681947B - Isolator is with double-deck airtight structure mouse hole door - Google Patents

Isolator is with double-deck airtight structure mouse hole door Download PDF

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Publication number
CN112681947B
CN112681947B CN202011499707.3A CN202011499707A CN112681947B CN 112681947 B CN112681947 B CN 112681947B CN 202011499707 A CN202011499707 A CN 202011499707A CN 112681947 B CN112681947 B CN 112681947B
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hole door
door
rat
mouse
hole
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CN112681947A (en
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崔华星
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Shanghai Tofflon Airex Science And Technology Co ltd
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Shanghai Tofflon Airex Science And Technology Co ltd
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Abstract

The invention discloses a rat hole door with a double-layer air-tight sealing structure for an isolator, which is characterized in that: the mouse hole door structure comprises a mouse hole inner flange arranged in a connecting hole of a front section cavity and a rear section cavity, a mouse hole outer flange matched with the mouse hole inner flange to form a mouse hole, and a mouse hole door arranged in a mouse hole opening, wherein a front-back double-layer air sealing structure is arranged between the mouse hole door and the mouse hole inner flange as well as between the mouse hole door and the mouse hole outer flange, and a limiting device used for limiting the position of the mouse hole door is arranged between the mouse hole door and the mouse hole inner flange; when one of the front section cavity and the rear section cavity is sterilized, the air sealing structure close to the other section cavity is filled with compressed air to form sealing with the rat hole door, and the air sealing structure close to the sterilization cavity is not filled with compressed air. The isolator provided by the invention is provided with the rat hole door with the double-layer air sealing structure, so that a sterilization blind area between the air sealing and the rat hole door can be avoided, the aim of completely sterilizing the rat hole can be fulfilled, the sterilization effect of the isolator is enhanced, and the sterility guarantee inside the isolator is increased.

Description

Isolator is with double-deck airtight structure mouse hole door
Technical Field
The invention relates to a rat hole door with a double-layer air-tight sealing structure for an isolator, belonging to the field of pharmaceutical machinery, in particular to the field of isolators of pharmaceutical equipment.
Background
With the rapid development of the isolator technology of pharmaceutical equipment, the segmented sterilization of the interior of the isolator gradually becomes a widely recommended sterilization mode, and a rat hole door with a sealing function needs to be arranged between a front cavity and a rear cavity of an isolator region boundary to achieve the purpose. The isolator needs to keep a relatively stable pressure difference gradient relative to a room, and sterilization treatment needs to be carried out on the inside of the isolator before production, so that a certain leakage rate requirement needs to be met, the isolator with the regional sterilization requirement needs to be provided with a sealing structure of the rat hole door at the junction of the front section and the rear section, meanwhile, the sterilization dead angle is avoided, and the rat hole door is convenient to operate and easy to clean.
And the mouse hole door of traditional mode only sets up inside certain cavity, adopts sliding mounting structure, and only the individual layer is airtight, and this kind of structure can have a sterilization blind area between airtight and mouse hole door seal department, mouse hole door and guide rail when the isolator carries out the sterilization, makes mouse hole department sterilization not thorough, can not reach the inside purpose of sterilizing completely of isolator.
Disclosure of Invention
The technical problem to be solved by the invention is as follows: when current isolator was disinfected, there was the problem of sterilization blind area between airtight and mouse hole door, mouse hole door and the slide rail.
In order to solve the problems, the technical scheme of the invention provides a rat hole door with a double-layer air-tight structure for an isolator, which is characterized in that: the mouse hole door structure comprises a mouse hole inner flange arranged in a connecting hole of a front section cavity and a rear section cavity, a mouse hole outer flange matched with the mouse hole inner flange to form a mouse hole, and a mouse hole door arranged in a mouse hole opening, wherein a front-back double-layer air sealing structure is arranged between the mouse hole door and the mouse hole inner flange as well as between the mouse hole door and the mouse hole outer flange, and a limiting device used for limiting the position of the mouse hole door is arranged between the mouse hole door and the mouse hole inner flange;
the mouse hole door is provided with a safety proximity switch for providing an inflation signal for the double-layer air sealing structure, when one of the front section cavity and the rear section cavity is sterilized, the air sealing structure close to the other section cavity is filled with compressed air to form sealing with the mouse hole door, and the air sealing structure close to the sterilization cavity is not filled with compressed air.
Preferably, the front-back double-layer air-tight structure comprises a front-end air-tight seal fixed in the front section cavity and a rear-end air-tight seal fixed in the rear section cavity, an air-tight groove used for containing the front-end air-tight seal and the rear-end air-tight seal is arranged on the inner flange of the rat hole, and the front-end air-tight seal and the rear-end air-tight seal are attached to the surface of the outer ring of the rat hole door after inflation and expansion to form the double-layer air-tight structure.
Preferably, a flange and a cavity sealing ring which play a role in sealing are arranged between the rat hole inner flange and the rear section cavity and between the rat hole outer flange and the front section cavity.
Preferably, the inner side of the rat hole inner flange and the inner side of the rat hole outer flange are provided with rat hole flange sealing rings to form a rat hole with a sealing structure.
Preferably, the safety proximity switch is butted on a rat hole door and a rat hole inner flange to form a switch signal.
Preferably, the limiting device comprises a rat hole door hanging piece and a rat hole door limiting column which are arranged on the rat hole door, and a rat hole door short hanging rod arranged on an inner flange of the rat hole, the rat hole door hanging piece is hung on the rat hole door short hanging rod to limit the rat hole door in vertical size, and the rat hole door limiting column is clamped on the rat hole door short hanging rod to prevent the rat hole door from inclining.
Preferably, the rear section cavity is provided with a rat hole door long hanging rod for placing the taken-out rat hole door.
Preferably, an integrally formed door handle is arranged on the rat hole door.
Preferably, the flange and cavity sealing ring and the rat hole flange sealing ring are made of silicon rubber or fluorine rubber or EPDM.
Compared with the prior art, the invention has the beneficial effects that:
the isolator provided by the invention is provided with the rat hole door with the double-layer air sealing structure, so that a sterilization blind area between the air sealing and the rat hole door can be avoided, the aim of completely sterilizing the rat hole can be fulfilled, the sterilization effect of the isolator is enhanced, and the sterility guarantee inside the isolator is increased.
Drawings
FIG. 1 is a schematic cross-sectional view of the present invention;
FIG. 2 is a schematic view of the rat hole door of the present invention closed;
FIG. 3 is a schematic view of the rat hole door of the present invention when opened.
Description of the reference numerals:
1. a mouse hole inner flange; 2. a mouse hole outer flange; 3. a mouse hole door; 4. preposing air sealing; 5. post-air sealing; 6. a flange and a cavity sealing ring; 7. a mouse hole flange seal ring; 8. a safety proximity switch; 9. a rat hole door hanging sheet; 10. a rat hole gate spacing post; 11. a short hanging rod at the mouse hole door; 12. mouse hole door long peg.
Detailed Description
In order to make the invention more comprehensible, preferred embodiments accompanied with figures are described in detail below.
As shown in fig. 1 to 3, the rat hole door with the double-layer air-tight seal structure for the isolator comprises a rat hole inner flange 1, a rat hole outer flange 2, a rat hole door 3, a front air-tight seal 4, a rear air-tight seal 5, a flange and cavity sealing ring 6, a rat hole flange sealing ring 7, a safety proximity switch 8, a rat hole door hanging sheet 9, a rat hole door limiting column 10, a rat hole door short hanging rod 11 and a rat hole door long hanging rod 12.
The inner mouse hole flange 1 is plugged into the front cavity and the rear cavity to be in butt joint to form a hole, the outer mouse hole flange 1 and the outer mouse hole flange 2 are clamped in a butt joint mode, the front cavity and the rear cavity are clamped tightly, the flange and the cavity sealing ring 6 are respectively plugged into outer ring grooves of the inner mouse hole flange 1 and the outer mouse hole flange 2 before clamping, and the mouse hole flange sealing ring 7 is plugged into an inner ring groove of the inner mouse hole flange 1 to form the mouse hole with a sealing structure. In this embodiment, the flange and cavity seal ring 6 and the rat hole flange seal ring 7 are made of materials such as silicon rubber, fluorine rubber, or EPDM, which are elastic and meet the FDA requirement, so as to perform a sealing function.
The front-mounted air seal 4 and the rear-mounted air seal 5 are respectively plugged into air seal grooves in the flange 1 in the rat hole, and compressed air pipes are connected to air nozzles of the front-mounted air seal 4 and the rear-mounted air seal 5 to form a double-layer air seal structure. In this embodiment, the front hermetic seal 4 and the rear hermetic seal 5 are made of a material such as silicone rubber or fluororubber to perform a sealing function.
The safety proximity switch 8 is installed on the rat hole door 3 and the rat hole inner flange 1, when the rat hole door 3 is plugged into a rat hole formed by butting the rat hole inner flange 1 and the rat hole outer flange 2, the safety proximity switch 8 is butted to form a switch signal, and the front-mounted air seal 4 and the rear-mounted air seal 5 can be prompted to be filled with compressed air.
The mouse hole door hanging piece 9 and the mouse hole door limiting column 10 are installed on the mouse hole door 3, the mouse hole door short hanging rod 11 is installed on the mouse hole inner flange 1, when the mouse hole door 3 is plugged into a mouse hole formed by butting the mouse hole inner flange 1 and the mouse hole outer flange 2, the mouse hole door hanging piece 9 can be hung on the mouse hole door short hanging rod 11 to limit the up-down size of the mouse hole door 3, and the mouse hole door limiting column 10 is placed on the mouse hole door short hanging rod 11 to prevent the mouse hole door 3 from inclining.
The long hanging rod 12 of the mouse hole door is arranged on the rear-section cavity, and the mouse hole door 3 can be placed on the long hanging rod 12 of the mouse hole door after being taken out.
The handle of the mouse hole door 3 and the mouse hole door 3 are made into an integral structure, so that the mouse hole door is attractive, free of butt joint gaps and easy to clean.
When the leakage rate of the isolator is tested before the sectional sterilization, the front-mounted air seal 4 and the rear-mounted air seal 5 are filled with compressed air, and the front-mounted air seal 4 and the rear-mounted air seal 5 are attached to the surface of the outer ring of the rat hole door 3 after being expanded, so that a sealing structure is formed.
When the front section cavity body sterilizes, the back section cavity body does not sterilize, the back-mounted air seal 5 is filled into compressed air, the front-mounted air seal 4 discharges compressed air, the back-mounted air seal 5 is attached to the outer ring surface of the rat hole door 3, a sealing structure is formed, a certain gap exists between the front-mounted air seal 4 and the rat hole door 3, and the front-mounted air seal 4 and the butt joint area of the rat hole door 3 can be sterilized during the sterilization of the front section cavity body.
When the front section cavity is not sterilized and the back section cavity is sterilized, the front air seal 4 is filled with compressed air, the back air seal 5 discharges the compressed air, the front air seal 4 is attached to the outer ring surface of the rat hole door 3 to form a sealing structure, and a certain gap exists between the back air seal 5 and the rat hole door 3, so that the back section cavity can be sterilized in the butt joint area of the back air seal 5 and the rat hole door 3.
When the project is integrally sterilized, the rat hole door 3 can be taken out from the rat hole formed by butting the rat hole inner flange 1 and the rat hole outer flange 2, hung on the long rat hole door hanging rod 12 arranged on the rear-section cavity and integrally sterilized.
The above embodiments are merely illustrative of the present invention, and not restrictive, and the material, type, or configuration may be changed without departing from the scope of the invention.

Claims (8)

1. The utility model provides an isolator is with double-deck airtight structure mouse hole door which characterized in that: the mouse hole door structure comprises a mouse hole inner flange (1) arranged in a connecting hole of a front section cavity and a rear section cavity, a mouse hole outer flange (2) matched with the mouse hole inner flange (1) to form a mouse hole, and a mouse hole door (3) arranged in a mouse hole opening, wherein a front-back double-layer air sealing structure is arranged between the mouse hole door (3) and the mouse hole inner flange (1) as well as between the mouse hole door (3) and the mouse hole outer flange (2), and a limiting device used for limiting the position of the mouse hole door (3) is arranged between the mouse hole door (3) and the mouse hole inner flange (1);
the mouse hole door (3) is provided with a safety proximity switch (8) for providing an inflation signal for the double-layer air-tight sealing structure, when one of the front section cavity and the rear section cavity is sterilized, the air-tight sealing structure close to the other section cavity is filled with compressed air to form sealing with the mouse hole door (3), and the air-tight sealing structure close to the sterilization cavity is not filled with compressed air;
the front-back double-layer air sealing structure comprises a front-mounted air seal (4) fixed in the front section cavity and a back-mounted air seal (5) fixed in the back section cavity, an air sealing groove used for containing the front-mounted air seal (4) and the back-mounted air seal (5) is formed in the rat hole inner flange (1), and the front-mounted air seal (4) and the back-mounted air seal (5) are attached to the surface of the outer ring of the rat hole door (3) after inflation and expansion to form the double-layer air sealing structure;
when the isolator leakage rate is tested before the subsection sterilization, the front-mounted air seal (4) and the rear-mounted air seal (5) are filled with compressed air, and the front-mounted air seal (4) and the rear-mounted air seal (5) are attached to the surface of the outer ring of the rat hole door (3) after being expanded to form a sealing structure;
when the front section cavity is sterilized and the rear section cavity is not sterilized, the rear air seal (5) is filled with compressed air, the front air seal (4) discharges the compressed air, so that the rear air seal (5) is attached to the outer ring surface of the rat-hole door (3) to form a sealing structure, and a certain gap is formed between the front air seal (4) and the rat-hole door (3), so that the front air seal (4) and a butt-joint area of the front air seal (4) and the rat-hole door (3) can be sterilized when the front section cavity is sterilized;
when the front-section cavity is not sterilized and the rear-section cavity is sterilized, the front-end air seal (4) is filled with compressed air, the rear-end air seal (5) discharges the compressed air, the front-end air seal (4) is attached to the surface of the outer ring of the rat hole door (3) to form a sealing structure, and a certain gap is formed between the rear-end air seal (5) and the rat hole door (3), so that the rear-end air seal (5) and a butt joint area of the rear-end air seal and the rat hole door (3) can be sterilized when the rear-section cavity is sterilized;
and if integral sterilization is carried out, taking the rat hole door (3) out of the rat hole formed by butting the rat hole inner flange (1) and the rat hole outer flange (2), and carrying out integral sterilization.
2. The rat hole door with the double-layer air-tight structure for the isolator as claimed in claim 1, wherein: and flanges and cavity sealing rings (6) which play a role in sealing are arranged between the rat hole inner flange (1) and the rear section cavity and between the rat hole outer flange (2) and the front section cavity.
3. The rat hole door with the double-layer air-tight structure for the isolator as claimed in claim 2, wherein: the inner sides of the rat hole inner flange (1) and the rat hole outer flange (2) are provided with rat hole flange sealing rings (7) to form a rat hole with a sealing structure.
4. The rat hole door with the double-layer air-tight structure for the isolator as claimed in claim 1, wherein: the safety proximity switch (8) is in butt joint with the rat hole door (3) and the rat hole inner flange (1) to form a switch signal.
5. The rat hole door with the double-layer air-tight structure for the isolator as claimed in claim 1, wherein: the limiting device comprises a mouse hole door hanging piece (9) and a mouse hole door limiting column (10) which are arranged on a mouse hole door (3) and a mouse hole door short hanging rod (11) which is arranged on a mouse hole inner flange (1), the mouse hole door hanging piece (9) is hung on the mouse hole door short hanging rod (11) to limit the mouse hole door (3) in vertical size, and the mouse hole door limiting column (10) is clamped on the mouse hole door short hanging rod (11) to prevent the mouse hole door (3) from inclining.
6. The rat hole door with the double-layer air-tight structure for the isolator as claimed in claim 1, wherein: and a mouse hole door long hanging rod (12) for placing the mouse hole door (3) after being taken out is arranged on the rear section cavity.
7. The rat hole door with the double-layer air-tight structure for the isolator as claimed in claim 1, wherein: and the mouse hole door (3) is provided with an integrally formed door handle.
8. The rat hole door with the double-layer air-tight structure for the isolator as claimed in claim 3, wherein: the flange and cavity sealing ring (6) and the rat hole flange sealing ring (7) are made of silicon rubber or fluorine rubber or EPDM.
CN202011499707.3A 2020-12-18 2020-12-18 Isolator is with double-deck airtight structure mouse hole door Active CN112681947B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202011499707.3A CN112681947B (en) 2020-12-18 2020-12-18 Isolator is with double-deck airtight structure mouse hole door

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Application Number Priority Date Filing Date Title
CN202011499707.3A CN112681947B (en) 2020-12-18 2020-12-18 Isolator is with double-deck airtight structure mouse hole door

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CN112681947A CN112681947A (en) 2021-04-20
CN112681947B true CN112681947B (en) 2023-03-10

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Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2542215Y (en) * 2002-04-26 2003-04-02 叶大林 Aseptic isolation transmitter
US20050232807A1 (en) * 2004-04-16 2005-10-20 Noboru Nishimura Sterile closure apparatus
CN205531960U (en) * 2016-04-14 2016-08-31 上海东富龙爱瑞思科技有限公司 Double glazing structure for isolator
CN205532012U (en) * 2016-04-14 2016-08-31 上海东富龙爱瑞思科技有限公司 Rat hole door structure for isolator
CN109025715A (en) * 2018-09-04 2018-12-18 上海翡诺医药设备有限公司 A kind of isolator bilayer zone sterilizing door mechanism
CN210685741U (en) * 2019-08-22 2020-06-05 山东新华医疗器械股份有限公司 Isolator pass-through box overhead door

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2542215Y (en) * 2002-04-26 2003-04-02 叶大林 Aseptic isolation transmitter
US20050232807A1 (en) * 2004-04-16 2005-10-20 Noboru Nishimura Sterile closure apparatus
CN205531960U (en) * 2016-04-14 2016-08-31 上海东富龙爱瑞思科技有限公司 Double glazing structure for isolator
CN205532012U (en) * 2016-04-14 2016-08-31 上海东富龙爱瑞思科技有限公司 Rat hole door structure for isolator
CN109025715A (en) * 2018-09-04 2018-12-18 上海翡诺医药设备有限公司 A kind of isolator bilayer zone sterilizing door mechanism
CN210685741U (en) * 2019-08-22 2020-06-05 山东新华医疗器械股份有限公司 Isolator pass-through box overhead door

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