CN112674803A

CN112674803A - Male genital HPV virus partition sampler

Info

Publication number: CN112674803A
Application number: CN202011351847.6A
Authority: CN
Inventors: 赵惠
Original assignee: Affiliated Hospital of Weifang Medical University
Current assignee: Affiliated Hospital of Weifang Medical University
Priority date: 2020-11-27
Filing date: 2020-11-27
Publication date: 2021-04-20
Anticipated expiration: 2040-11-27
Also published as: CN112674803B

Abstract

The invention discloses a male genital HPV virus partition sampler, which comprises a sampling main body, wherein a main inner cavity is arranged in the sampling main body, an annular sprayer is matched in the main inner cavity, three limiting ribs are arranged on the outer side of the annular sprayer and positioned in limiting sliding grooves in the inner wall of the main inner cavity, a side inner cavity is arranged on the side surface of the main inner cavity, a connecting threaded hard tube is arranged in the side inner cavity, the bottom of the connecting threaded hard tube is butted with the annular hard tube, an adjusting nut is limited at the top of the side inner cavity and meshed with the connecting threaded hard tube, the top of the connecting threaded hard tube is butted with a pressurizing flusher through a connecting hose, and the bottom of the sampling main body is butted with a centrifugal tube. The core of the invention is that the annular sprayer provides high-pressure flushing liquid to wash a target part to obtain a tissue specimen. The target part flushed by the annular sprayer can be accurately adjusted through the adjusting nut, and accurate extraction in a subarea mode is achieved; compared with the traditional brush wiping method, the method greatly reduces the wound and improves the comfort.

Description

Male genital HPV virus partition sampler

Technical Field

The invention relates to the field of medical instruments, in particular to a male genital HPV virus partition sampler.

Background

HPV virus is the abbreviation of human papilloma virus, a genus of papilloma vacuolato virus A of the papovaviridae family, a sexually transmitted disease caused by infection with spherical DNA virus. The main types are HPV1, 2, 6, 11, 16, 18, 31, 33 and 35, etc., and long-term infection of HPV16 and 18 types can be related to female cervical cancer.

The virus mainly infects human epidermis and mucosa squamous epithelium, more than 130 kinds of virus are isolated so far, the virus only invades human beings, is not pathogenic to other animals, and can be eliminated by human bodies after being treated by a formal system. It has also been proposed by scholars that the virus will be carried for life. Scientific research and demonstration are also required for this argument.

At present, the method for acquiring HPV virus from the surface of male genital organs is mainly a brush wiping method, can not acquire HPV virus in a subarea manner, can cause certain trauma in the sampling process, easily causes unnecessary infection, can cause stronger pain for patients, and has poorer comfort in the sampling process. In order to solve the existing problems, the invention designs a male genital HPV virus partition sampler.

Disclosure of Invention

The invention aims to solve the defects that the existing method for acquiring HPV virus from the surface of male genitals is mainly a brush wiping method, can not acquire HPV virus in a subarea manner, can cause certain trauma in the sampling process, is easy to cause unnecessary infection, can cause stronger pain of a patient, is poorer in comfort in the sampling process and the like, and provides a subarea sampler for the HPV virus of the male genitals.

In order to achieve the purpose, the invention provides the following technical scheme:

a male genital HPV virus partition sampler comprises a sampling main body, wherein a main inner cavity is arranged inside the sampling main body, the inner part of the main inner cavity is matched with an annular sprayer, the outer side of the annular sprayer is provided with three limiting ribs, the inner wall of the main inner cavity is correspondingly provided with three limiting sliding grooves, wherein the limiting rib is positioned in the limiting sliding groove, the inner side of the annular sprayer is uniformly provided with a plurality of fine holes towards the circle center, a side inner cavity is arranged on the side surface of the main inner cavity in a penetrating way, a connecting thread hard tube is arranged inside the side inner cavity, wherein the bottom of the connecting thread hard tube is butted with the annular sprayer, the top of the side inner cavity is limited by an adjusting nut, wherein adjusting nut and the looks meshing of connecting thread hard tube, the top of connecting thread hard tube is passed through coupling hose and is docked with the pressurization flusher, the bottom and the centrifuging tube dock of sample main part.

Preferably, the annular threaded hard pipe is in a circular ring shape; the connecting thread hard tube is L-shaped, the bottom of the connecting thread hard tube is a horizontal end, and the top of the connecting thread hard tube is a vertical end; wherein, the horizontal end at the bottom of the connecting thread hard tube is butted with the annular sprayer. The circular ring-shaped sprayer can completely cover the target sampling position, the extracting solution is uniformly sprayed on the male genitals through the fine holes on the inner side of the circular ring-shaped sprayer, a flushing liquid water column with specific pressure can be provided to non-invasively flush the male genitals, and the sample is extracted by flushing the skin of the target position.

Preferably, the positions of three limiting sliding grooves in the inner wall of the main inner cavity correspond to the positions of three limiting ribs in the outer side of the annular threaded hard tube; wherein, clearance fit is adopted between the limiting rib and the limiting sliding groove. The limiting ribs are mainly used for limiting the annular threaded hard pipe, so that the annular threaded hard pipe can only move along the direction of the limiting sliding groove.

Preferably, the surface of the vertical end at the top of the connecting threaded hard tube is provided with an external thread; wherein, the vertical end at the top of the connecting thread hard tube is meshed with the adjusting nut through threads. The connecting thread hard pipe is mainly used for connecting the ring-shaped sprayer so as to facilitate the ring-shaped sprayer to move up and down, wherein the connecting thread hard pipe moves up or down under the meshing action of the threads by rotating the adjusting nut in different directions, thereby realizing the movement of the position of the ring-shaped sprayer. The target part flushed by the annular sprayer can be accurately adjusted, and accurate extraction in a subarea mode is achieved.

Preferably, the upper limit and the lower limit of the adjusting nut are positioned at the top of the side inner cavity, and the part of the adjusting nut is positioned at the outer side of the side inner cavity; wherein, the surface of adjusting nut evenly is provided with the sawtooth. The friction force contacted with the adjusting nut can be increased through the saw teeth, and the adjusting nut is convenient to rotate.

Preferably, two ends of the connecting hose are respectively fixedly connected with the connecting threaded hard pipe and the pressurizing flusher in an expansion mode; wherein, the structure of the pressurizing flusher is the same as that of the injector. The pressurizing flusher is detachably connected with the connecting hose, after the extracting solution is injected into the pressurizing flusher, the pressurizing flusher is in soft butt joint with the connecting hose, the pressurizing flusher is pressed, and the extracting solution with certain pressure intensity is injected into the annular sprayer through the connecting threaded hard pipe.

Preferably, the bottom of the sampling body is fixed with the centrifuge tube by engaging threads. Can dismantle between centrifuging tube and the sample main part, can directly put into the centrifuging tube that contains HPV virus extract, one-step target in place has reduced unnecessary sample transfer process, and is safer, prevents that the sample from exposing the polluted environment to and the sample runs off and reduces and detect positive rate.

Compared with the prior art, the invention has the beneficial effects that: the invention relates to a male genital HPV virus partition sampler, which is characterized in that a high-pressure extracting solution is sprayed out by a ring-shaped sprayer with holes, and the skin of a target part is brushed under certain pressure to extract a sample; the target part flushed by the annular sprayer can be accurately adjusted, and accurate extraction in a subarea manner is achieved; compared with the traditional brush wiping method, the method greatly reduces the wound, reduces the infection risk and improves the comfort.

Drawings

Fig. 1 is a schematic front view of the present invention.

Fig. 2 is a partially enlarged view of a portion a in fig. 1.

Fig. 3 is a schematic top view of the present invention.

Fig. 4 is a partially enlarged view of fig. 3 at B.

Fig. 5 is a cross-sectional view at C-C in fig. 3.

Fig. 6 is a partial enlarged view of fig. 5 at D.

Fig. 7 is a partial enlarged view at E in fig. 5.

Fig. 8 is a partial cross-sectional view at F-F in fig. 7.

In the figure: 1-a sampling main body, 2-a main inner cavity, 3-a ring-shaped sprayer, 4-a limiting rib, 5-a limiting chute, 6-a pore, 7-a side inner cavity, 8-a connecting threaded hard tube, 9-an adjusting nut, 10-a sawtooth, 11-a connecting hose, 12-a pressurizing flusher and 13-a centrifuge tube.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

Referring to fig. 1-8, the present invention provides a technical solution:

a male genital organ HPV virus partition sampler comprises a sampling main body 1, wherein a main inner cavity 2 is arranged inside the sampling main body 1, a ring-shaped sprayer 3 is matched inside the main inner cavity 2, three limiting ribs 4 are arranged on the outer side of the ring-shaped sprayer 3, three limiting sliding chutes 5 are correspondingly arranged on the inner wall of the main inner cavity 2, the limiting ribs 4 are positioned in the limiting sliding chutes 5, a plurality of fine holes 6 are uniformly arranged on the inner side of the ring-shaped sprayer 3 towards the circle center, a side inner cavity 7 is arranged on the side surface of the main inner cavity 2 in a penetrating manner, a connecting thread hard pipe 8 is arranged inside the side inner cavity 7, the bottom of the connecting thread hard pipe 8 is butted with the ring-shaped sprayer 3, an adjusting nut 9 is limited on the top of the side inner cavity 7, the adjusting nut 9 is meshed with the connecting thread hard pipe 8, the top of the connecting thread hard pipe 8 is butted with a pressurizing flusher 12 through a connecting hose 11, the bottom of the sampling body 1 is interfaced with a centrifuge tube 13.

The annular sprayer 3 is in an annular shape; the connecting threaded hard tube 8 is L-shaped, the bottom of the connecting threaded hard tube 8 is a horizontal end, and the top of the connecting threaded hard tube 8 is a vertical end; wherein, the horizontal end at the bottom of the connecting thread hard pipe 8 is butted with the ring-shaped sprayer 3. The circular ring-shaped sprayer 3 can more comprehensively and noninvasively wash the male genitals, the extracting solution is uniformly sprayed on the male genitals through the fine holes 6 on the inner side of the circular ring-shaped sprayer 3 under certain pressure, and the skin of the target part is washed to extract a sample.

The positions of three limiting sliding chutes 5 in the inner wall of the main inner cavity 2 correspond to the positions of three limiting ribs 4 in the outer side of the annular sprayer 3; wherein, clearance fit is adopted between the limiting rib 4 and the limiting sliding groove 5. The limiting rib 4 is mainly used for limiting the ring-shaped sprayer 3, so that the ring-shaped sprayer 3 can only move along the direction of the limiting sliding groove 5.

The surface of the vertical end at the top of the connecting threaded hard tube 8 is provided with external threads; wherein, the vertical end of the top of the connecting thread hard tube 8 is engaged with the adjusting nut 9 through threads. The connecting thread hard pipe 8 is mainly used for connecting the ring type sprayer 3 so that the ring type sprayer 3 can move up and down, wherein the connecting thread hard pipe 8 can move up or down under the meshing action of the threads by rotating the adjusting nut 9 in different directions, thereby realizing the movement of the position of the ring type sprayer 3. The target part flushed by the annular sprayer 3 can be accurately adjusted, and accurate extraction in a subarea mode is achieved.

The adjusting nut 9 is vertically limited at the top of the side inner cavity 7, and the part of the adjusting nut 9 is positioned at the outer side of the side inner cavity 7; wherein, the outer surface of the adjusting nut 9 is evenly provided with saw teeth 10. The friction force in contact with the adjustment nut 9 can be increased by the serrations 10, facilitating the rotation of the adjustment nut 9.

Two ends of the connecting hose 11 are respectively fixedly connected with the connecting threaded hard pipe 8 and the pressurizing flusher 12 in an expanding way; the pressurized flusher 12 is identical in construction to the syringe. The pressurizing flusher 12 and the connecting hose 11 are detachable, after extracting liquid is injected into the pressurizing flusher 12, the pressurizing flusher 12 is butted with the connecting soft part 11, the pressurizing flusher 12 is pressed, and extracting liquid with certain pressure is injected into the annular sprayer 3 through the connecting threaded hard pipe 8.

The bottom of the sampling body 1 is fixed by engaging with the centrifugal tube 13 through screw threads. Can dismantle between centrifuging tube 13 and the sample main part 1, can directly put into the centrifuge with centrifuging tube 13 that contains HPV virus extract, one-step target in place has reduced unnecessary sample transfer process, and is safer, prevents that the sample from exposing the polluted environment to and the sample runs off and reduce and detect positive rate.

The working principle of the invention is as follows:

first, the pressure washer 12 and the centrifuge tube 13 are butted against the sampling body 1. After the extraction liquid is injected into the pressure syringe 12, the pressure syringe 12 is connected to the connection screw pipe 8 through the connection soft part 11. The centrifuge tube 13 is butted against the bottom of the sampling body 1.

Secondly, the position between the ring-type shower 3 and the male genitals is accurately adjusted. The genitals of a male patient are placed in the main inner cavity 2, the saw teeth 10 are rubbed, the adjusting nut 9 is rotated, and the connecting threaded hard pipe 8 is slowly moved upwards or downwards under the meshing action of the threads, so that the annular sprayer 3 is slowly moved upwards or downwards. The target part flushed by the annular sprayer 3 can be accurately adjusted, and accurate extraction in a subarea mode is achieved.

Finally, the samples were washed. Pressing the pressurizing flusher 12, injecting extracting solution with certain pressure into the annular sprayer 3 through the connecting threaded hard tube 8, enabling the extracting solution with certain pressure to uniformly and comprehensively impact on genital skin through a plurality of fine holes 6 on the inner side of the annular sprayer 3, and flushing the skin of a target part to obtain extracting solution containing HPV virus, wherein the extracting solution containing HPV virus finally flows into the centrifuge tube 13. After the centrifugal tube 13 containing the HPV virus extracting solution and the sampling main body 1 are separated, the centrifugal tube can be directly placed into a centrifugal machine to be in place in one step, the redundant sample transfer process is reduced, the safety is higher, the sample is prevented from exposing and polluting the environment, the sample loss is prevented, and the detection positive rate is reduced.

It will be evident to those skilled in the art that the invention is not limited to the details of the foregoing illustrative embodiments, and that the present invention may be embodied in other specific forms without departing from the spirit or essential attributes thereof. The present embodiments are therefore to be considered in all respects as illustrative and not restrictive, the scope of the invention being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein. Any reference sign in a claim should not be construed as limiting the claim concerned.

Claims

1. A male genital HPV virus zonal sampler, characterized in that: comprises a sampling main body (1), a main inner cavity (2) is arranged in the sampling main body (1), the main inner cavity (2) is internally matched with a ring-shaped sprayer (3), the outer side of the ring-shaped sprayer (3) is provided with three limit ribs (4), the inner wall of the main inner cavity (2) is correspondingly provided with three limit chutes (5), wherein the limit ribs (4) are positioned in the limit chutes (5), the inner side of the ring-shaped sprayer (3) is uniformly provided with a plurality of pores (6) towards the circle center, the side surface of the main inner cavity (2) is provided with a side inner cavity (7) in a run-through manner, a connecting thread hard pipe (8) is arranged in the side inner cavity (7), the bottom of the connecting thread hard pipe (8) is connected with the ring-shaped sprayer (3) in a relative manner, the top of the side inner cavity (7) is limited by an adjusting nut (9), wherein the adjusting nut (9) is meshed with the connecting thread hard pipe (, the top of the connecting thread hard tube (8) is butted with a pressurizing flusher (12) through a connecting hose (11), and the bottom of the sampling main body (1) is butted with a centrifugal tube (13).

2. The HPV viral zonal sampler for male genitalia according to claim 1, wherein: the annular sprayer (3) is in a circular ring shape; the connecting thread hard tube (8) is L-shaped, the bottom of the connecting thread hard tube (8) is a horizontal end, and the top of the connecting thread hard tube (8) is a vertical end; wherein, the horizontal end of the bottom of the connecting thread hard tube (8) is butted with the ring-shaped hard tube (3).

3. The HPV viral zonal sampler for male genitalia according to claim 1, wherein: the positions of three limiting sliding chutes (5) in the inner wall of the main inner cavity (2) correspond to the positions of three limiting ribs (4) in the outer side of the annular sprayer (3); wherein, the spacing rib (4) is in clearance fit with the spacing sliding groove (5).

4. The HPV viral zonal sampler for male genitalia according to claim 1, wherein: the surface of the vertical end at the top of the connecting threaded hard pipe (8) is provided with an external thread; wherein, the vertical end of the top of the connecting thread hard tube (8) is meshed with the adjusting nut (9) through threads.

5. The HPV viral zonal sampler for male genitalia according to claim 1, wherein: the adjusting nut (9) is vertically limited at the top of the side inner cavity (7), and the part of the adjusting nut (9) is positioned at the outer side of the side inner cavity (7); wherein, the outer surface of the adjusting nut (9) is evenly provided with saw teeth (10).

6. The HPV viral zonal sampler for male genitalia according to claim 1, wherein: two ends of the connecting hose (11) are respectively fixedly connected with the connecting threaded hard pipe (8) and the pressurizing flusher (12) in an expanding way; wherein, the structure of the pressure flusher (12) is the same as that of the injector.

7. The HPV viral zonal sampler for male genitalia according to claim 1, wherein: the bottom of the sampling main body (1) is engaged and fixed with the centrifugal tube (13) through threads.