CN112674700A - Capsule endoscope system - Google Patents
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- CN112674700A CN112674700A CN201910995843.2A CN201910995843A CN112674700A CN 112674700 A CN112674700 A CN 112674700A CN 201910995843 A CN201910995843 A CN 201910995843A CN 112674700 A CN112674700 A CN 112674700A
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Abstract
The invention relates to the technical field of medical instruments, in particular to a capsule endoscope system which comprises a capsule endoscope and an in-vitro control system. The capsule endoscope comprises a capsule, a data acquisition part, a magnetic part and a communication part, wherein the data acquisition part, the magnetic part and the communication part are arranged in the capsule, the data acquisition part is used for acquiring image information in a machine body, the magnetic part provides an endoscope action function and a magnetic induction heat function, and the communication part processes the image information acquired by the data acquisition part and transmits the image information through wireless communication. The external control system is a moving magnetic field for the capsule endoscope to move or an alternating magnetic field for generating a magnetocaloric effect. The capsule endoscope provided by the invention has an image pick-up function for shooting the inside of a detected body, a wireless communication function for transmitting in-vivo information to an in-vitro control system, and a function for moving and generating a magneto-caloric effect under the control of the in-vitro control system.
Description
Technical Field
The invention relates to the technical field of medical instruments, in particular to a capsule endoscope system.
Background
Currently, a capsule endoscope is an endoscope that a patient can examine by oral administration. The medical endoscope has a built-in image acquisition camera and is in wireless communication with an in-vitro wireless communication device to acquire images in the alimentary canal, and a doctor receives the images shot by the capsule endoscope by using an in-vitro instrument to know the condition of the alimentary canal of a detected person so as to diagnose the condition of the patient. The capsule endoscopy has the advantages of convenient examination, no wound, no lead, no pain, no cross infection, no influence on normal work of patients and the like, expands the visual field of the digestive tract examination, overcomes the defects of poor tolerance, inapplicability to the elderly, the infirm and the critical illness and the like of the traditional plug-in endoscopy, and can be used as a first-choice method for diagnosing digestive tract diseases, particularly small intestine diseases.
The existing capsule endoscope only can perform the functions of examination and diagnosis in a human body and has no treatment function. The motion control of the existing capsule endoscope can be controlled by a built-in micro motor and a magnetic field source arranged outside the body, and the examination requirement cannot be met only by the peristalsis of the alimentary canal of the human body. The micro motor controls the movement mode, the motor needs high energy consumption, and an in-vitro accurate and complex control system is needed.
Disclosure of Invention
In order to solve the above problems, an embodiment of the present invention provides a capsule endoscope system, which controls a movement of a capsule endoscope and a subject and performs a magnetic thermal treatment on a lesion site at the same time, and the technical solution is as follows:
a capsule endoscope system comprising a capsule endoscope and an extracorporeal control system, the capsule endoscope comprising:
a data acquisition part for acquiring image information in a body, the image information including normal image information and lesion image information;
the magnetic part comprises a support part, a magnetic ball and a magnetocaloric piece, the magnetic ball is arranged in a spherical cavity formed by the support part, the magnetic ball freely rotates in the spherical cavity, and the magnetocaloric piece generates a magnetic induction heat effect under the action of an in vitro alternating magnetic field;
the communication part processes the image information collected by the data collection part and sends the image information through wireless communication;
the extracorporeal control system comprises:
a capsule driving unit for providing an action magnetic field for the magnetic round balls and an alternating magnetic field for the magnetocaloric piece;
and a control unit that receives the normal image information or the lesion image information transmitted via the communication unit and transmits a different control command to the capsule driving unit, wherein the capsule driving unit supplies the operating magnetic field or the alternating magnetic field based on the control command.
The technical scheme provided by the invention at least comprises the following beneficial effects:
the capsule endoscope provided by the invention has an image pick-up function for shooting the inside of a detected body, a wireless communication function for transmitting in-vivo information to an in-vitro control system, and a function for moving and generating a magneto-caloric effect under the control of the in-vitro control system. The capsule endoscope device enters the alimentary canal by being swallowed into the body of the subject through the esophagus in the subject, moves by the peristalsis of the alimentary canal and moves under the action of a constant magnetic field in vitro. The peristalsis of the alimentary canal often cannot fully examine all tissues inside the alimentary canal, and the capsule endoscope is driven to move in a detected body by the control movement of an in-vitro control system through the action of a constant magnetic field on the magnetic round balls inside the capsule endoscope. When the lesion site is judged and found through the image information obtained by the control unit, the magnetocaloric therapy is carried out on the lesion site in the cavity of the examined body.
Additional advantages, objects, and features of the invention will be set forth in part in the description which follows and in part will become apparent to those having ordinary skill in the art upon examination of the following or may be learned from practice of the invention.
In the present invention, unless otherwise expressly specified or limited, the term "disposed" is to be construed broadly, as meaning either a static or dynamic connection, a non-removable or removable connection, or a rest thereon or in a particular orientation; "fixed" is a static connection; the sleeve joint can be sleeved outside a certain part without contacting, sleeved outside the certain part and in threaded connection with the certain part, or sleeved outside the certain part and in detachable connection; "threaded connection" means a connection by thread engagement, rotation; "rotationally connected" means connected by balls, rollers, etc., and one or both of the two connectors can rotate; the term "transmission connection" refers to a connection mode that is indirectly connected by means of a chain, a conveyor belt or a connecting rod and acts synchronously; "communicate" means "fixed" or "connected" together and the internal spaces are in communication; "electrically connected" means that the electronic components are connected by a conductive medium; unless otherwise specifically defined, the specific meanings of the above terms in the present invention can be understood by those of ordinary skill in the art according to specific situations.
Drawings
FIG. 1 is a schematic structural diagram of a capsule endoscope system provided by an embodiment of the present invention;
FIG. 2 is a functional block diagram of a capsule endoscope provided by an embodiment of the present invention;
FIG. 3 is a functional block diagram of an extracorporeal control system according to an embodiment of the present invention;
in the figure:
1 capsule endoscope, 10 capsules, 11 data acquisition part, 12 magnetic part, 120 support piece, 1200 spherical cavity, 121 magnetic sphere, 122 magnetocaloric piece, 122a magnetocaloric body, 122b sealing film, 13 communication part, 130 mounting plate, 131 circuit board, 1310 second communication module, 132 connection part, 133 battery,
2 external control system, 20 capsule driving unit, 200 Helmholtz coil, 201 workbench, 21 control unit, 210 first communication module, 211 magnetic field control module, 2110 signal generation module, 2111 amplitude adjustment module, 2112 signal processing module, 2113 signal feedback module and 212 upper computer.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention will be described in further detail below. It is to be understood that the described embodiments are merely exemplary of the invention, and not restrictive of the full scope of the invention. All other embodiments, which can be obtained by a person skilled in the art without any inventive step based on the embodiments of the present invention, are within the scope of the present invention. In the description of the present invention, it is to be understood that the terms "first", "second", "third", "fourth", "fifth", and the like are used merely for distinguishing between descriptions and are not to be construed as indicating or implying relative importance.
In the description of the present invention, it is to be understood that, if the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", etc. are used for indicating the orientation or positional relationship indicated based on the drawings, they are only for convenience of describing the present invention and simplifying the description, but do not indicate or imply that the device or element referred to must have a specific orientation, be constructed in a specific orientation and be operated, and thus, should not be construed as limiting the present invention.
Example one
The present embodiment is an example of an application of the entire capsule endoscope system including the capsule endoscope 1 and the extracorporeal control system 2. The capsule endoscope 1 includes a data acquisition section 11, a magnetic section 12, and a communication section 13. The extracorporeal control system 2 comprises a capsule drive unit 20 and a control unit 21. The capsule endoscope 1 collects image information and biological information in a body through the data collection part 11, sends the image information and the biological information to the control unit 21 through the communication part 13, the control unit 21 performs analysis and judgment or manual judgment through the image information and the biological information, starts the capsule driving unit 20 to generate an external constant magnetic field so that the magnetic round balls 121 of the magnetic part 12 act in the constant magnetic field, or generates an alternating magnetic field so that the magnetocaloric element 122 generates a magnetocaloric effect in the alternating magnetic field, and performs magnetocaloric treatment on a lesion part in a cavity of a detected body.
The capsule endoscope provided by the invention has an image pick-up function for shooting the inside of a detected body, a wireless communication function for transmitting in-vivo information to an in-vitro control system, and a function for moving and generating a magneto-caloric effect under the control of the in-vitro control system. The capsule endoscope device enters the alimentary canal by being swallowed into the body of the subject through the esophagus in the subject, moves by the peristalsis of the alimentary canal and moves under the action of a constant magnetic field in vitro. The peristalsis of the alimentary canal often cannot fully examine all tissues inside the alimentary canal, and the capsule endoscope is driven to move in a detected body by the control movement of an in-vitro control system through the action of a constant magnetic field on the magnetic round balls inside the capsule endoscope. When the lesion site is found by the judgment of the image information and the biological information obtained by the control unit, the magnetocaloric treatment is performed on the lesion site in the cavity of the subject.
Example two
The present example is an embodiment of a capsule endoscope structure according to the present invention.
Referring to fig. 1, the capsule endoscope 1 according to the present invention is generally elliptical, two data acquisition units 11 are fixed to both ends, a magnetic unit 12 is disposed in the middle, a magnetocaloric element 122 of the magnetic unit 12 extends to the surface of the capsule 10, the surface of the capsule 10 except the magnetocaloric element 122 is made of a transparent material, and the data acquisition units 11 are fixed to a mounting plate 130 of the communication unit 13 in a state of facing outward from one end of the capsule endoscope 1.
The capsule 10 is made of a non-digestible polymer transparent material, such AS poly-4-methyl-1-pentene (PMP), styrene/butadiene copolymer (K resin), styrene/acrylonitrile copolymer (AS), polynorbornene, cellulose-based transparent plastic (CA, CN), etc.
The magnetic part 12 includes a support 120, a magnetic sphere 121 and a magnetocaloric element 122, the magnetic sphere 121 is disposed in a spherical cavity 1200 formed inside the support 120, the magnetic sphere 121 freely rotates in the spherical cavity 1200, and the magnetocaloric element 122 generates a magnetic induction thermal effect under the action of an external alternating magnetic field.
Because the magnetic ball 121 arranged in the capsule endoscope has magnetism, the magnetic ball 121 can act on the capsule endoscope under the action of a constant magnetic field generated by an in-vitro control system and is also driven to follow the action, so that the whole capsule endoscope 1 is driven to act.
When a diseased part is found through the data acquisition part 11, the in vitro control system is switched to a mode of generating an alternating magnetic field, so that the magnetic sphere 121 rotates in the spherical cavity 100, and the capsule endoscope 1 stops near the diseased part; while the magnetocaloric element 122 generates a magnetocaloric effect.
The support member 120 extends to the surface of the capsule 10 and is spaced apart from other portions, and is made of an inorganic heat insulating material to reduce the influence of heat generated from the magneto-thermal member 122 on other portions. The magnetic sphere 121 is a Bake magnetic sphere with a smooth surface, has a diameter of 3-8mm, and is a spherical strong magnet formed by finely processing NdFeB magnetic ore.
The magnetocaloric component 122 includes a magnetocaloric element 122a and a sealing film 122b, the sealing film 122b is disposed at the opening of the annular groove to wrap the magnetocaloric element 122a in the annular groove, and the magnetocaloric element 122a generates heat in the alternating magnetic field provided by the capsule driving unit 20.
The magnetocaloric element 122a is a monolithic ferromagnetic thermal seed made of a ferromagnetic metal group doped with a non-magnetic metal element.
The magnetocaloric elements 122a comprise core-shell particles of a magnetic metal-organic framework composite, with a particle size of 40-70 nm. Specific results for core-shell particles are exemplified by: fe3O4-SH@PDA@Au、Fe3O4-SH@PDA@MnFe2O4、Fe3O4-SH@PDA@ZnFe2O4、Fe3O4-SH@PDA@ZnFe2O4、MnxZn(1-x)Fe2O4@DSPE-PEG2000、MnxZn(1-x)Fe2O4-DMSA @ DSPE-PEG2000 (magnetic nanoparticles coated with pegylated phospholipids). The magnetic heat body provides heat to the affected part under the action of the applied alternating magnetic field for treating and can minimize toxic side effect to normal tissue.
In particular, Fe3O4The preparation method of the-SH @ PDA @ Au magnetic heat body is as follows.
Fe3O4Preparation of-SH: mixing Fe3Cl3And NaAc was dissolved in ethylene glycol in a water bath at 70 ℃ for 30min to give a brown solution, followed by the rapid addition of 2-mercaptoethanol. And (3) quickly transferring the solution into a polytetrafluoroethylene liner, putting the polytetrafluoroethylene liner into a reaction kettle, reacting for 10 hours at 205 ℃, taking out and cooling to room temperature. Removing supernatant, washing substrate with water for several times, and magnetically separating, and finally dispersing in water.
Fe3O4Preparation of-SH @ PDA: taking Fe3O4And (3) magnetically separating the suspension of the-SH to remove water, adding the suspension into HCL-Tris buffer solution, ultrasonically dispersing, adding dopamine hydrochloride (PDA) and Sodium Dodecyl Sulfate (SDS), and stirring for reacting for 4-6 hours. After the reaction is finished, the mixture is washed by magnetic separation water for multiple times until the clear liquid is colorless and transparent and has no foam.
Fe3O4Preparation of-SH @ PDA @ Au: weighing AgNO3Dissolving in ethylene glycol, adding polyvinylpyrrolidone (PVP), completely dissolving, placing the solution in an oil bath, heating to 160 ℃ from room temperature, magnetically stirring for reaction for 1.5h, and measuring from the beginning of heating to obtain silver nano cubic solution; diluting with water, magnetically stirring to homogenize, and dropwise adding chloroauric acid (HAuCl)4) After dropping, the reaction was continued for 20 min. Adding mercaptopropionic acid (MPA) to react for 30min, adding NaCl solid to dissolve until saturation, stirring overnight to dissolve to generate silver chloride (AgCl), centrifuging the obtained reaction solution, removing supernatant, adding water, performing ultrasonic dispersion, centrifuging again, repeating for 3 times, and washing off redundant NaCl to obtain Aunanocage stock solution; the synthesized Fe3O4Mixing the-SH @ PDA nano example with an Aunanocage stock solution, performing ultrasonic dispersion, performing oscillation adsorption for more than 12 hours at 30 ℃, performing magnetic separation, and washing to obtain the product.
The magnetocaloric body 122a is based on a carrier liquid and a surfactant. The base carrier fluid comprises a water base, a hydrocarbon base, a kerosene base or an organic compound base. The base carrier liquid is 0.01MPBS, and the surfactant is oleic acid or polyethylene glycol.
The wall material of the sealing film 122b can resist digestion of the digestive tract, but when the magnetic nanoparticles generate a magnetocaloric effect, the magnetic nanoparticles are melted away due to the magnetocaloric effect. The specific membrane sealing wall material can resist gastric acid, is not easily degraded by various protein digestive enzymes in the digestive tract, and can be melted under the action of magnetic heat. For example, the magnetic nanoparticles are wrapped in the sealing film wall material made of paraffin, graphene oxide modified paraffin and other materials.
EXAMPLE III
This embodiment is an implementation of data acquisition, transmission and magnetic field control of a capsule endoscope system provided by the present invention, please refer to fig. 2 and 3.
A data acquisition unit 11 that acquires image information and biological information in a subject; the data acquisition part 11 comprises a light source and a camera, and the light source and the camera are powered by a power module. The Light source can irradiate illumination Light into the subject, and is realized by using an LED (Light Emitting Diode) or the like. The camera includes an optical system for forming an optical image and an image pickup Device such as a CCD (Charge Coupled Device) or a CMOS (Complementary Metal Oxide Semiconductor), and the optical system of the camera is connected to a circuit board 131 of a communication unit 13 to be described later in a communication manner, and the image pickup Device is configured to two-dimensionally arrange a plurality of pixels, each of which receives an optical image formed on a light receiving surface by the optical system and photoelectrically converts the optical image to generate in-vivo image data of the subject.
The communication unit 13 transmits image information to the extracorporeal control system by wireless communication. The communication unit 13 includes a mounting board 130, a circuit board 131, a connection unit 132, and a battery 133. Mounting plate 130 provides support for the entire capsule 10, prevents collapse of capsule 10, and also provides a mounting base for circuit board 121, connection portion 132, battery 133, and support member 120.
The circuit board 131 is arranged on the mounting plate 130 at one end in the capsule endoscope 1, and the circuit board 131 is provided with a power management module, a second wireless communication module 1310 and a signal processing module; the mounting board 130 on the other side is also provided with a first wireless communication module 1310, and is connected with the signal processing module on the circuit board 131 through the connecting portion 132. The respective data acquisition parts 11 at both ends send the acquired data to the circuit board 131 for processing, and then are respectively in communication connection with the extracorporeal control system through the respective first wireless communication modules 1310 at both ends.
The battery 133 is electrically connected to the power management module on the circuit board 131, and the battery mounting box extending to the surface of the capsule 10 is disposed on the mounting plate 130, so that after the capsule is used by a subject, the battery in the battery mounting box can be taken out after the capsule 10 is opened from the outside, and meanwhile, the magnetocaloric element 122a and the sealing film 122b can be assembled on the magnetocaloric element 122 again to recycle the whole capsule endoscope. The battery 123 can be provided in two for backup.
The circuit board 131 performs a/D conversion on the analog image data output from the data acquisition unit 11 to generate digital image data, and performs amplification, filtering, and other processing on the digital image data, and transmits the digital image data to the outside through the wireless communication module 1310 on the data circuit board 131. The wireless communication module 1310 can be a Micro XBee module of Digi or an MBH7WLZ17 module. The Micro XBee supports the ZigBee 3.0 standard and simultaneously supports the Bluetooth with low power consumption, and the size is 13mm multiplied by 19 mm. The MBH7WLZ17 supports the IEEE802.11b/g standard, integrates RF, baseband and MAC on a chip with a package size of 8.0mm multiplied by 1.2mm, and can strengthen a filter of an RF part to effectively reduce interference. The connecting portion 122 is embedded in the supporting member 10 to connect the data collecting portions 11 at both ends.
The light from the outside of the body can be received from the cameras 111 at the two ends of the capsule 10 to the maximum extent, the images generated by the light are processed by the circuit board 131 and then returned to the wireless communication module 1310, and image digital signals are transmitted between the wireless communication module 1310 and the receiving unit of the outside of the body control system. The acquired image digital signals are displayed on a graphical user interface of an in-vitro control system, the tumor part can be accurately identified through identification and assistance of the inside of a detected body by artificial experience, for example, a level set method is adopted to obtain the class contour characteristics, and a Mumford-Shah model is adopted to perform separation calculation on the tumor part.
Referring to fig. 3, the extracorporeal control system 2 includes a capsule driving unit 20 and a control unit 21.
The capsule driving unit 20 provides an alternating magnetic field for the magnetocaloric unit 122 and provides an operating magnetic field for the magnetic sphere 121, and specifically, the capsule driving unit 20 includes a helmholtz coil 200, a table 201 for placing a subject and an operation driving unit (not shown in the drawing) disposed in the internal magnetic field, the table 201 includes a table top and the operation driving unit, the operation driving unit can be a three-axis system or a mechanical arm, and the operation driving unit controls the table top to operate in the magnetic field generated by the helmholtz coil through an upper computer 212 described later.
The control unit 21 includes a first communication module 210, a magnetic field control module 211, and an upper computer 212. The upper computer 212 is a computer including a liquid crystal display capable of cleaning the image acquired by the display data acquisition section 11. The magnetic field control module 211 includes a signal generation module 2110, an amplitude adjustment module 2111, a signal processing module 2112, and a signal feedback module 2113. The upper computer 212 uses Direct Digital Synthesis (DDS) technology, and performs frequency presetting and control word setting on the DDS signal generator 2110 through a microcontroller to output a dc signal or a sinusoidal ac signal. The DDS signal generator 2110 may be a DDS chip, such as AD9850, AD9851 or AD9852 from AD.
The amplitude adjusting module 2111 realizes the adjustability of the amplitude of the sinusoidal alternating current signal through the combination of a DA converter and a multiplier, thereby indirectly controlling the heating effect of the magnetocaloric component 122. The model of the DA converter is TLC5615, and the model of the multiplier is AD 633.
The signal processing module 2112 mainly comprises a filter circuit and a power amplification circuit, and for a direct-current signal generated by the DDS signal generator 2110, the driving current of the helmholtz coil is obtained only through the power amplification circuit; for the sinusoidal ac signal generated by the signal generator 2110, the stable driving alternating current of the helmholtz coil with certain amplitude is obtained through the current processing and power amplification of the filtering part.
The signal feedback acquisition module 2113 is mainly used for acquiring the magnetic field generated by the helmholtz coil and feeding the magnetic field back to the upper computer 212. The specific signal feedback acquisition module 2113 is a fluxgate meter, and comprises a fluxgate probe and a host computer, wherein the fluxgate probe and the host computer are connected through a cable, and the host computer is connected with the upper computer 212 through a cable; the host provides control signals to drive the probe and process output signals of the probe to the upper computer 212, analyzes the angle and vector composite value of the magnetic field, is convenient for the upper computer 212 to monitor in real time, adjusts the input current signals through the control signal generation module 2110, and achieves the purpose of automatically adjusting the magnetic field generated by the Helmholtz coil. The specific signal feedback acquisition module 2113 may be of a CH-370 type (manufactured by beijing cuihai jiacheng-cheng-ci magneto).
The first communication module 210 receives the image information sent by the communication unit 13 through wireless communication and sends the image information to the host computer 212, and specifically, the first communication module 210 also adopts a Micro xbe module of Digi or an MBH7WLZ17 module.
The software programming of the extracorporeal control system 1 is mainly directed to the operation control of the capsule endoscope 1 in the subject or the magnetocaloric control of the magnetocaloric element 12.
The working process of the invention is as follows:
for the action mode of the capsule endoscope 1, the image data acquired by the data acquisition part 11 is transmitted to the upper computer 212 through wireless communication and displayed on the liquid crystal display of the upper computer 212, when the image information is judged to be normal image information manually, the software control button of the upper computer 212 is started to send a first control instruction to the magnetic field control module 211 and the workbench 201, the capsule endoscope 1 acts in the action magnetic field, and meanwhile, the workbench 201 acts in the magnetic field generated by the Helmholtz coil to drive the capsule endoscope 1 to move in the detected body.
When the capsule endoscope 1 moves in the subject, a doctor finds a suspected lesion, manually controls the magnetic field control module 211 and the workbench 201 to stop operating through software control of the upper computer 212, and simultaneously segments the suspected lesion, the segmented result is compared with a database of a training set of the upper computer 212, when the comparison result shows that the lesion is detected (in the actual diagnosis and treatment process, diagnosis needs to be performed by combining other detection means), the upper computer 212 sends a second control instruction to the DDS signal generator, the DDS signal generator sends a sinusoidal alternating current signal, and the helmholtz coil is started to generate an alternating magnetic field, so that the magnetocaloric element 122a in the magnetocaloric element 12 of the capsule endoscope 1 generates a magnetocaloric effect, the sealing film 122b is heated and melted, and the sealing film is released to the lesion for treatment.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents, improvements and the like that fall within the spirit and principle of the present invention are intended to be included therein.
Claims (8)
1. A capsule endoscope system comprising a capsule endoscope and an extracorporeal control system, the capsule endoscope comprising:
a data acquisition part for acquiring image information in a body, the image information including normal image information and lesion image information;
the magnetic part comprises a support part, a magnetic ball and a magnetocaloric piece, the magnetic ball is arranged in a spherical cavity formed by the support part, the magnetic ball freely rotates in the spherical cavity, and the magnetocaloric piece generates a magnetic induction heat effect under the action of an in vitro alternating magnetic field;
the communication part processes the image information collected by the data collection part and sends the image information through wireless communication;
the extracorporeal control system comprises:
a capsule driving unit for providing an action magnetic field for the magnetic round balls and an alternating magnetic field for the magnetocaloric piece;
and a control unit that receives the normal image information or the lesion image information transmitted via the communication unit and transmits a different control command to the capsule driving unit, wherein the capsule driving unit supplies the operating magnetic field or the alternating magnetic field based on the control command.
2. The capsule endoscopic system of claim 1, wherein said capsule endoscope further comprises a capsule for housing said data acquisition portion, magnetic portion and communication portion.
3. The capsule endoscopic system of claim 2, wherein both ends of said capsule are transparent and each end thereof is provided with one said data acquisition portion and one said communication portion.
4. The capsule endoscopic system of claim 3, wherein said magnetic portion is located in a non-transparent portion between two ends of said capsule, said support member surface forming an annular groove into which said magnetocaloric element is inserted.
5. The capsule endoscopic system of claim 4, wherein the magnetocaloric element comprises a magnetocaloric body and a sealing film, the sealing film is disposed at the opening of the annular groove to enclose the magnetocaloric body in the annular groove, and the magnetocaloric body generates heat in the alternating magnetic field provided by the capsule driving unit.
6. The capsule endoscopic system of claim 5, wherein said magnetocaloric element is a monolithic ferromagnetic thermal seed made of a ferromagnetic metal body doped with a non-magnetic metal element.
7. The capsule endoscopic system of claim 5, wherein the magnetocaloric body comprises magnetic nanoparticles, the magnetic nanoparticles being core-shell particles having a magnetic metal-organic framework composite.
8. The capsule endoscopic system of claim 7, wherein said magnetocaloric body further comprises a base carrier fluid and a surfactant.
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| CN201910995843.2A CN112674700A (en) | 2019-10-18 | 2019-10-18 | Capsule endoscope system |
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| CN201910995843.2A CN112674700A (en) | 2019-10-18 | 2019-10-18 | Capsule endoscope system |
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| CN1909824A (en) * | 2004-01-07 | 2007-02-07 | 奥林巴斯株式会社 | Capsule-type medical apparatus, medical capsule housing, and production method thereof |
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| CN201719699U (en) * | 2010-08-05 | 2011-01-26 | 福州浩联医疗科技有限公司 | Medical magnetic induction thermoseed |
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