CN112674323A

CN112674323A - Composition for promoting growth and development

Info

Publication number: CN112674323A
Application number: CN202011472807.7A
Authority: CN
Inventors: 曹晶晶; 崔跃然; 崔渭然
Original assignee: Tianjin Jingran Technology Co ltd
Current assignee: Tianjin Jingran Technology Co ltd
Priority date: 2020-12-15
Filing date: 2020-12-15
Publication date: 2021-04-20

Abstract

The invention discloses a composition for promoting growth and development, which comprises the following components in percentage by weight: 20-60% of protein and 40-80% of fat. The composition disclosed by the invention is simple in components and convenient to eat, can provide energy and protein required by infants and patients every day, can obviously increase the weight, and has excellent social and economic values.

Description

Composition for promoting growth and development

Technical Field

The invention provides a product for a patient with dysplasia to eat, and belongs to the field of food.

Background

With the improvement of living standard, the incidence of milk protein allergy in infants is increasing year by year in recent years. Milk protein allergies are statistically increased by more than 7% per year. For milk protein allergic infants, the better results can be obtained by the intervention of supplementary food and the avoidance of allergen, and the infants generally can be desensitized smoothly in 2 to 3 years old and normally eat foods such as milk, eggs and the like. However, in the early stage of the complementary food intervention, a small part of milk protein allergic infants have the situations of poor intestinal tract condition, poor growth and development and slow weight increase, and even the situation that the weight increase is stopped for 3 to 6 months. Therefore, there is an urgent need to develop a safe food for milk protein allergy infants that can rapidly improve body weight.

With the wide popularization of clinical nutrition, clinical nutrition support becomes an increasingly important treatment means during hospitalization of patients. Research shows that clinical nutrition support during hospitalization can obviously improve the constitution of patients, shorten the treatment period and save treatment cost and medical resources. Some patients consume large substrates during treatment, such as tumors, and patients who cannot eat food for a long time after operation, and need to provide a high-energy-density and safe food.

High-energy fat-and-oil foods can provide enough energy for milk protein allergic infants and patients in hospital, but are easy to cause new problems such as fat diarrhea or severe diarrhea. In view of the above, it is urgent to develop a formulation capable of solving the above problems, which can rapidly and effectively solve the existing clinical problems without causing or aggravating diarrhea.

Disclosure of Invention

The invention aims to provide a composition capable of promoting growth and development.

Another object of the present invention is to provide a composition free of common allergens to satisfy the safety of milk protein allergic people.

It is another object of the present invention to provide a food product that is capable of delivering high energy shocks during patient treatment, reducing disease consumption.

The technical scheme of the invention for achieving the aim comprises the following components in percentage by weight:

protein 20-60%, and fat 40-80%

Preferably, protein 25-55%, fat 45-75%;

more preferably, the protein is 30-50% and the fat is 50-70%

Further preferably, the protein is 35-45% and the fat is 55-65%

Still more preferably, the protein content is 40% and the fat content is 60%

The protein of the invention comprises one or more than two of proteins in aquatic products, poultry, livestock, dairy products or eggs. The aquatic protein comprises one or more than two of fish, shrimp or crab; the poultry protein comprises one or more than two of chicken, duck and goose; the livestock protein comprises one or more of pork, beef or mutton; the dairy product comprises one or more of whole milk powder, skimmed milk powder or whey protein such as cow milk, goat milk, camel milk, mare milk, etc.

The protein may be a hydrolyzed protein.

In order to meet the requirements of the growth and development of infants, the protein is preferably red meat, such as pork, beef, mutton and the like; more preferably, the protein is beef.

The fat comprises saturated fatty acid and/or unsaturated fatty acid. The saturated fatty acid comprises animal oil, such as lard, beef tallow, mutton fat or chicken fat; the unsaturated fatty acid comprises vegetable oil, including one or more of oleum Rapae, soybean oil, oleum Cocois, oleum Arachidis Hypogaeae, oleum Helianthi, palm oil, oleum Camelliae and oleum Olivarum. The grease can be combined in any weight ratio; preferably, either weight ratio is in the range of 1:1 to 3.

Preferably, the grease is one or more than two of rapeseed oil, coconut oil or sunflower seed oil; more preferably, the weight ratio of the grease is 1:1:1-1:3:3.

The fat of the invention is common grease on the market.

The composition disclosed by the invention is simple in components and convenient to eat, can be combined with daily diet, such as added into complementary food or milk, can provide energy and protein required by a baby and a patient every day, can obviously increase the weight, and has excellent social and economic values.

Test examples

1 clinical data

1.1 general data 104 outpatients of children with dysplasia were randomly divided into 52 treatment groups and 52 control groups. Before all cases are treated, the height and the weight of the infant are not increased for more than 2 months, and the weight of the infant is lower than that of a normal infant of the same age. The treatment group had 52 cases, of which 34 were male, 28 were female, aged 5-24 months, with an average of 11 months, of which 44 were milk protein allergic. Control group 52, of which 30 men and 32 women had an age of 5 months to 20 months, with an average of 12.5 months, of which 0 is allergic to milk protein. Two groups of clinical data were comparable (P >0.05) by statistical treatment.

1.2 treatment methods both groups were given normal diet feeding. The treatment group orally took the composition prepared by the weight ratio of 50% beef and 50% fat in the invention example 9, wherein the fat is coconut oil, sunflower seed oil and rapeseed oil which are mixed according to the weight ratio of 1:1: 1. Each person was fed 10 grams of the composition of the invention per day on a meal basis. Other milk and supplementary food are eaten normally without changing the original feeding mode. A treatment course is 30 days after continuous administration. Body weight and height were observed before and after treatment. The control group orally takes the high-energy formula powder according to the taking method and dosage of the instruction.

1.3 Standard judgment of curative Effect evaluation in accordance with the Standard for growth and development of children under 7 years old in China. The effect is shown: the weight is increased by more than or equal to 200 g; the method has the following advantages: the weight is increased by less than 200 g; and (4) invalidation: the body weight did not increase.

2. Results

2.1 the two groups of therapeutic effects are compared and shown in Table 1.

TABLE 1 comparison of the two therapeutic effects

。

3. Discussion of the related Art

The composition and the control group have the functions of increasing weight and promoting growth and development. The effect of the composition group of the invention is better than that of the control group. The composition of the invention is particularly suitable for milk protein allergic infants.

Detailed Description

In one embodiment of the invention, any one of the weight proportion combinations of 20-60% of protein and 40-80% of fat is selected, such as 20% of protein and 80% of fat; or protein 60%, fat 40%; or protein 25%, fat 75%.

In another embodiment of the invention, the protein is 25-55% and the fat is 45-75%, such as 25% of protein and 74% of fat; or protein 55%, fat 45%; or protein 40% and fat 60%.

In the third embodiment of the present invention, any combination of protein 30-50% and fat 50-70% by weight is selected, such as protein 30% and fat 70%; or 50% protein, 50% fat; or protein 38%, fat 62%.

In a fourth embodiment of the invention, any combination of protein 35-45% and fat 55-65% by weight is selected, such as protein 35%, fat 65%, or protein 45%, fat 55%, or protein 42%, fat 58%, or protein 40%, fat 60%.

The protein comprises one or more than two of fish, shrimp or crab in any weight ratio; or one or more than two of chicken, duck or goose in any weight ratio; or one or more than two of pig, cattle or sheep in any weight ratio. Preferably; the protein can be any weight ratio combination of the animal proteins.

The fat comprises saturated fatty acid or/and unsaturated fatty acid. The saturated fatty acid comprises animal oil such as one or more of lard, beef tallow, mutton fat or chicken fat; the unsaturated fatty acid comprises vegetable oil, including one or more of oleum Rapae, soybean oil, oleum Cocois, oleum Arachidis Hypogaeae, oleum Helianthi, oleum Camelliae, palm oil, and oleum Olivarum. The grease can be combined in any weight ratio; preferably, either weight ratio is in the range of 1:1 to 3.

In order to be convenient to eat and carry, the protein and the fat are prepared into powder.

In a fifth embodiment of the invention, any of the protein and fat ratios of embodiments 1 to 4 are selected. The protein is selected from one or more of beef protein, chicken protein, pork protein, egg protein, whole milk powder, whey protein or fish protein. The proteins can be combined in any weight ratio; preferably, the proteins are combined in equal weight ratios. The protein may be a hydrolyzed protein; the hydrolyzed protein is preferably hydrolyzed whey protein.

The fat is selected from unsaturated vegetable fatty acid; preferably, the unsaturated fatty acid comprises one or more of coconut oil, rapeseed oil, peanut oil, soybean oil, tea oil, corn oil, sunflower seed oil or rapeseed oil. The unsaturated fatty acids can be combined in any weight ratio; preferably, the unsaturated fatty acids are combined in equal weight ratios.

In a sixth embodiment of the invention, any one of the protein and fat ratios of embodiments 1 to 4 is selected. The protein is selected from one or more of beef, chicken or fish; the fat is selected from coconut oil, sunflower seed oil and rapeseed oil; the coconut oil, the sunflower seed oil and the rapeseed oil can be combined according to any weight ratio; preferably, the coconut oil, the sunflower seed oil and the rapeseed oil are mixed according to the weight ratio of 1:1: 1; more preferably, the meat and the grease are both powder.

In a seventh embodiment of the invention, the protein to fat ratio of any one of embodiments 1 to 4 is selected. The protein is selected from one or more of beef, chicken or fish; the fat is selected from coconut oil, soybean oil and peanut oil; the coconut oil, the soybean oil and the peanut oil can be combined according to any weight ratio; preferably, the coconut oil, the soybean oil and the peanut oil are mixed according to the weight ratio of 1:2: 1; more preferably, the meat and the grease are both powder.

In an eighth embodiment of the invention, any one of the protein and fat ratios of embodiments 1 to 4 is selected. The protein is chicken; the fat is selected from coconut oil, sesame oil and peanut oil; the coconut oil, the sesame oil and the peanut oil can be combined according to any weight ratio; preferably, the coconut oil, the sesame oil and the peanut oil are mixed according to the weight ratio of 1:1: 2; more preferably, the meat and the grease are both powder.

In the ninth embodiment of the present invention, in order to meet the growth and development requirements of milk protein allergic infants, the protein and fat ratio of any one of embodiments 1 to 4 is selected. The protein is selected from one or more of beef, chicken, hydrolyzed whey protein or duck meat; preferably, the protein is beef or chicken; more preferably, the protein is beef. The fat is selected from coconut oil, sunflower seed oil and rapeseed oil; the coconut oil, the sesame oil and the peanut oil can be combined according to any weight ratio; preferably, the coconut oil, the sunflower seed oil and the rapeseed oil are mixed according to the weight ratio of 1:1: 1; more preferably, the meat and the grease are both powder.

In order to reduce the introduction of allergen, the grease powder is embedded by starch. The composition of the invention is taken together with infant formula powder and supplementary food according to the required amount of the corresponding month-old in daily diet, can rapidly supplement missing protein and fat, and meets the requirements of infant growth and development.

Claims

1. A composition for promoting growth and development comprises the following components in parts by weight: 20-60% of protein and 40-80% of fat.

2. The composition according to claim 1, wherein the weight ratio of the components is as follows: protein 25-55%, fat 45-75%.

3. The composition according to claim 1, wherein the weight ratio of the components is as follows: protein 30-50%, fat 50-70%.

4. The composition according to claim 3, wherein the weight ratio of the components is as follows: 35-45% of protein and 55-65% of fat.

5. The composition according to claim 4, wherein the weight ratio of the components is as follows: protein 40% and fat 60%.

6. The composition of any one of claims 1-5, wherein the protein comprises one or more of aquatic, poultry, livestock, dairy, or egg proteins; the aquatic protein comprises one or more than two of fish, shrimp or crab;

the poultry protein comprises one or more than two of chicken, duck and goose;

the livestock protein comprises one or more of pork, beef or mutton; more preferably, the protein is beef;

the dairy product comprises one or more of whole milk powder, skimmed milk powder or whey protein such as cow milk, goat milk, camel milk and mare milk;

the protein may be a hydrolyzed protein.

7. A composition according to any one of claims 1 to 6, wherein the fat comprises saturated and/or unsaturated fatty acids;

the saturated fatty acid is animal oil such as lard, beef tallow, mutton fat or chicken fat;

the unsaturated fatty acid is vegetable oil, including one or more of oleum Rapae, soybean oil, oleum Cocois, oleum Arachidis Hypogaeae, oleum Helianthi, palm oil, oleum Camelliae and oleum Olivarum;

the weight ratio of any two of the grease is 1: 1-3.

8. The composition according to any one of claims 1 to 7, wherein the fat is coconut oil, sunflower oil and rapeseed oil in a weight ratio of 1:1: 1; the coconut oil, the soybean oil and the peanut oil are mixed according to the weight ratio of 1:2: 1.