CN112656837A - Composition for treating beriberi - Google Patents
Composition for treating beriberi Download PDFInfo
- Publication number
- CN112656837A CN112656837A CN202110019271.1A CN202110019271A CN112656837A CN 112656837 A CN112656837 A CN 112656837A CN 202110019271 A CN202110019271 A CN 202110019271A CN 112656837 A CN112656837 A CN 112656837A
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- Prior art keywords
- composition
- salicylic acid
- borneol
- treating beriberi
- treating
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention provides a composition for treating beriberi, which comprises the following components in percentage by mass: 57.4-79.5% of water, 6-15% of polyalcohol, 1-10% of thickening agent, 3-5% of salicylic acid, 1-5% of surfactant, 1-3% of borneol and 0.1-1% of sophora flavescens extract. The invention can achieve 99.9% killing effect on staphylococcus aureus, escherichia coli and candida albicans. Can effectively relieve itching in time, treat beriberi and prevent relapse.
Description
Technical Field
The invention relates to a composition for treating beriberi.
Background
Beriberi is a physical disease troubling patients all the time, is often accompanied by pruritus, also can cause burning and pain, and also can cause blister, erosion and liquid seepage on local parts. The repetitive operation is annoying. Most of the currently common treatment schemes in the market adopt topical glucocorticoids (such as dexamethasone, hydrocortisone, triamcinolone acetonide, fluticasone and the like) or antifungal drugs (such as amorolfine, ciclopirox olamine, miconazole, econazole, netilmicin and the like), although the products have effective effects, the products are not suitable for long-term use, have other consequences such as dependence dermatitis and the like, have poor instant effect and are repeated after use.
Disclosure of Invention
The invention aims to overcome the defects in the prior art, and provides a composition for treating beriberi, which can effectively relieve itching in time, treat beriberi and prevent relapse.
In order to solve the technical problems, the invention adopts the technical scheme that: the composition for treating dermatophytosis comprises the following components in parts by mass:
further, the salicylic acid comprises artificially synthesized salicylic acid and naturally extracted salicylic acid, and the purity of the salicylic acid is more than 99.5%; the borneol comprises synthetic borneol and natural extracted borneol, and the purity of the borneol is 90%.
Further, the polyalcohol is one or more of glycerol, butanediol, propylene glycol, polyethylene glycol-8, polyethylene glycol-32 or dipropylene glycol.
Further, the thickening agent is one or more of magnesium aluminum silicate or poloxamer 407 or polyacrylate cross-linked polymer-6.
Further, the surfactant is one or more of laureth-4, laureth-8 or PEG-40 hydrogenated castor oil.
Further, the preparation method of the composition comprises the following steps: dissolving Borneolum and salicylic acid in mixed solution of surfactant and polyalcohol, dissolving thickener in water under heating, adding dissolved Borneolum and salicylic acid solution into water phase, stirring, cooling to 50 deg.C, adding radix Sophorae Flavescentis extract, and stirring.
Further, the composition can be used for soaking in an aqueous product, and can also be used for topical application in a gel cream product.
Compared with the prior art, the invention has the beneficial effects that: the bactericidal composition achieves 99.9% of killing effect on staphylococcus aureus, escherichia coli and candida albicans. Can effectively relieve itching in time, treat beriberi and prevent relapse.
Detailed Description
It is easily understood that according to the technical solution of the present invention, a person skilled in the art can propose various alternative structures and implementation ways without changing the spirit of the present invention. Therefore, the following detailed description is merely illustrative of the technical solutions of the present invention, and should not be construed as being all of the present invention or limiting or restricting the technical solutions of the present invention.
The composition for treating dermatophytosis comprises the following components in parts by mass: 57.4-79.5% of water, 6-15% of polyalcohol, 1-10% of thickening agent, 3-5% of salicylic acid, 1-5% of surfactant, 1-3% of borneol and 0.1-1% of sophora flavescens extract.
Wherein the salicylic acid comprises artificially synthesized salicylic acid and naturally extracted salicylic acid, and the purity of the salicylic acid is more than 99.5%; the borneol comprises synthetic borneol and natural extracted borneol, and the purity of the borneol is 90%; the radix Sophorae Flavescentis extract is solution or powder obtained by water extraction, alcohol extraction or supercritical extraction; the polyalcohol is one or more of glycerol, butanediol, propylene glycol, polyethylene glycol-8, polyethylene glycol-32 or dipropylene glycol; the thickening agent is one or more of magnesium aluminum silicate or poloxamer 407 or polyacrylate cross-linked polymer-6; the surfactant is one or more of laureth-4, laureth-8, PEG-40 hydrogenated castor oil.
The preparation method of the combination formula comprises the following steps: dissolving Borneolum and salicylic acid in mixed solution of surfactant and polyalcohol, dissolving thickener in water under heating, adding dissolved Borneolum and salicylic acid solution into water phase, stirring, cooling to 50 deg.C, adding radix Sophorae Flavescentis extract, and stirring. The composition can be used for soaking in water aqua product, or can be used for topical application in gel cream product.
The following description is given with reference to specific examples
Example 1
Weighing 5g of butanediol and 1g of glycerol as polyhydric alcohol, 10g of poloxamer 407 as a thickening agent, 1g of laureth-4 as a surfactant, 3g of salicylic acid, 1g of borneol and 0.1g of radix sophorae flavescentis extract, dissolving the borneol and the salicylic acid in a mixed solution of the surfactant and the polyhydric alcohol, putting the thickening agent in 78.9g of water, heating and stirring until the mixture is dissolved, adding the dissolved mixed solution of the borneol and the salicylic acid into a water phase after the mixture is completely dissolved, stirring and uniformly mixing, cooling to 50 ℃, adding the radix sophorae flavescentis extract, and uniformly stirring to obtain the composition for treating beriberi.
Example 2
Weighing 5g of butanediol and 5g of polyethylene glycol as polyhydric alcohol, 2g of poloxamer 407 as a thickening agent, 2g of laureth-4 as a surfactant, 5g of salicylic acid, 1g of borneol and 0.5g of radix sophorae flavescentis extract, dissolving the borneol and the salicylic acid in a mixed solution of the surfactant and the polyhydric alcohol, putting the thickening agent in 79.5g of water, heating and stirring until the mixture is dissolved, adding the dissolved mixed solution of the borneol and the salicylic acid into a water phase after the mixture is completely dissolved, stirring and uniformly mixing, cooling to 50 ℃, adding the radix sophorae flavescentis extract, and uniformly stirring to obtain the composition for treating beriberi.
Example 3
Weighing 10g of glycerol and 2g of polyethylene glycol as polyhydric alcohol, 3g of laureth-4 as surfactant, 4g of salicylic acid, 3g of borneol and 1g of radix sophorae flavescentis extract, dissolving borneol and salicylic acid in a mixed solution of the surfactant and the polyhydric alcohol, placing a thickening agent in 77g of water, heating and stirring until the borneol and the salicylic acid are dissolved, adding the dissolved mixed solution of the borneol and the salicylic acid into an aqueous phase after the borneol and the salicylic acid are completely dissolved, stirring and mixing uniformly, cooling to 50 ℃, adding the radix sophorae flavescentis extract, and stirring uniformly to obtain the composition for treating beriberi.
Example 4
Weighing 3g of butanediol, 10g of glycerol and 2g of polyethylene glycol as polyhydric alcohol, 15g of poloxamer 407 as a thickening agent, 5g of laureth-4 as a surfactant, 5g of salicylic acid, 2g of borneol and 0.5g of radix sophorae flavescentis extract, dissolving the borneol and the salicylic acid in a mixed solution of the surfactant and the polyhydric alcohol, putting the thickening agent in 57.5g of water, heating and stirring until the thickening agent is dissolved, adding the dissolved mixed solution of the borneol and the salicylic acid into a water phase after the thickening agent is completely dissolved, stirring and mixing uniformly, cooling to 50 ℃, adding the radix sophorae flavescentis extract, and stirring uniformly to obtain the composition for treating beriberi.
Example 5
Weighing 15g of glycerol as polyhydric alcohol, 4g of laureth-4 as surfactant, 5g of salicylic acid, 1g of borneol and 1g of radix sophorae flavescentis extract, dissolving the borneol and the salicylic acid in a mixed solution of the surfactant and the polyhydric alcohol, placing a thickening agent in 74g of water, heating and stirring until the borneol and the salicylic acid are dissolved, adding the dissolved mixed solution of the borneol and the salicylic acid into a water phase after the borneol and the salicylic acid are completely dissolved, stirring and mixing uniformly, cooling to 50 ℃, adding the radix sophorae flavescentis extract, and stirring uniformly to obtain the composition for treating beriberi.
The technical scope of the present invention is not limited to the above description, and those skilled in the art can make various changes and modifications to the above-described embodiments without departing from the technical spirit of the present invention, and such changes and modifications should fall within the protective scope of the present invention.
Claims (7)
1. The composition for treating dermatophytosis is characterized by comprising the following components in parts by mass:
2. the composition for treating beriberi as claimed in claim 1, wherein the salicylic acid comprises artificially synthesized salicylic acid and naturally extracted salicylic acid, and the purity of the salicylic acid is more than 99.5%; the borneol comprises synthetic borneol and natural extracted borneol, and the purity of the borneol is 90%.
3. The composition for treating beriberi according to claim 1, wherein the polyol is one or more of glycerol or butylene glycol or propylene glycol or polyethylene glycol-8 or polyethylene glycol-32 or dipropylene glycol.
4. The composition for treating beriberi according to claim 1, wherein the thickener is one or more of magnesium aluminum silicate or poloxamer 407 or polyacrylate crosspolymer-6.
5. The composition for treating beriberi according to claim 1, wherein the surfactant is one or more of laureth-4, laureth-8, or PEG-40 hydrogenated castor oil.
6. The composition for treating beriberi according to any one of claims 1 to 5, wherein the composition is prepared by a method comprising the following steps: dissolving Borneolum and salicylic acid in mixed solution of surfactant and polyalcohol, dissolving thickener in water under heating, adding dissolved Borneolum and salicylic acid solution into water phase, stirring, cooling to 50 deg.C, adding radix Sophorae Flavescentis extract, and stirring.
7. The composition for treating beriberi according to claim 6, wherein the composition can be used for soaking in a water aqua product or can be used for topical application in a gel cream product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110019271.1A CN112656837A (en) | 2021-01-07 | 2021-01-07 | Composition for treating beriberi |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110019271.1A CN112656837A (en) | 2021-01-07 | 2021-01-07 | Composition for treating beriberi |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN112656837A true CN112656837A (en) | 2021-04-16 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202110019271.1A Pending CN112656837A (en) | 2021-01-07 | 2021-01-07 | Composition for treating beriberi |
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| CN (1) | CN112656837A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115337233A (en) * | 2022-06-24 | 2022-11-15 | 广州环亚化妆品科技股份有限公司 | Gel mask with mild acne removing effect and preparation method thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1067384A (en) * | 1991-06-01 | 1992-12-30 | 贵州神奇制药有限公司 | The manufacture method of Pharmaccutical cotton gripped between toes for curing beriberi |
| CN103908491A (en) * | 2013-12-23 | 2014-07-09 | 广西博科药业有限公司 | Composition for treating beriberi and foot stench, and preparation method thereof |
-
2021
- 2021-01-07 CN CN202110019271.1A patent/CN112656837A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1067384A (en) * | 1991-06-01 | 1992-12-30 | 贵州神奇制药有限公司 | The manufacture method of Pharmaccutical cotton gripped between toes for curing beriberi |
| CN103908491A (en) * | 2013-12-23 | 2014-07-09 | 广西博科药业有限公司 | Composition for treating beriberi and foot stench, and preparation method thereof |
Non-Patent Citations (2)
| Title |
|---|
| 刘福强等主编: "《医师案头用药参考》", 31 March 2012, 中国中医药出版社 * |
| 道苠编著: "《家庭金钥匙》", 31 March 1996, 西藏人民出版社 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115337233A (en) * | 2022-06-24 | 2022-11-15 | 广州环亚化妆品科技股份有限公司 | Gel mask with mild acne removing effect and preparation method thereof |
| CN115337233B (en) * | 2022-06-24 | 2023-05-30 | 广州环亚化妆品科技股份有限公司 | Gel mask with mild acne removing effect and preparation method thereof |
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Application publication date: 20210416 |