CN112617905A - Ultrasonic microprobe, ultrasonic endoscopy system and biopsy sampling system - Google Patents

Abstract

The invention discloses an ultrasonic microprobe, an ultrasonic endoscope inspection system and a biopsy sampling system, and belongs to the field of medical instruments. The ultrasonic microprobe comprises an ultrasonic transducer, a driving shaft and a conduit, wherein the driving shaft is connected with the ultrasonic transducer, the ultrasonic transducer is arranged in the conduit, a plurality of positioning marks are axially arranged on the outer side surface of a far-end pipe section of the conduit, and a preset distance larger than zero is reserved between every two adjacent positioning marks, so that a distance scale is formed. According to the invention, the distance scale is arranged on the catheter of the ultrasonic microprobe, so that a doctor can conveniently and accurately and visually determine the position of a focus under the visual field of an endoscope, and accurate positioning guidance is provided for subsequent biopsy sampling, thereby solving the problem that the clinical pain point of the focus cannot be quickly and visually positioned at present, simplifying clinical examination operation, reducing clinical consumable cost and shortening operation time.

Description

Ultrasonic microprobe, ultrasonic endoscopy system and biopsy sampling system

Technical Field

The invention relates to the technical field of medical instruments, in particular to an ultrasonic microprobe, an ultrasonic endoscopic examination system provided with the ultrasonic microprobe and a biopsy sampling system enabling biopsy forceps to be combined with the ultrasonic endoscopic examination system.

Background

Endobronchial ultrasound (REBUS) can clearly display changes on the surface of respiratory mucosa and tiny focuses of a deep tissue structure under the mucosa due to the characteristics of high frequency, small diameter and the like, and plays a very important role in clinical diagnosis and treatment of trachea, particularly peripheral bronchi.

The broncho-intracavity ultrasound microprobe can quickly confirm and position a focus in an operation, further clarify a suspicious focus of chest CT examination, improve the diagnosis rate and shorten the bronchoscopy operation time. If necessary, the focus confirmed and positioned by the ultrasonic microprobe is subjected to biopsy, and further pathological diagnosis is carried out. Typically, an ultrasound microprobe is passed through a jaw tract (i.e., instrument channel) of a bronchoscope (i.e., bronchoscope) to reach a lesion site. When the ultrasonic microprobe is examined, the ultrasonic microprobe can go deep into the far end position in the bronchial cavity, which can not be seen by a bronchoscope, and when the focus observed by the microprobe needs to be biopsied, a certain auxiliary method is needed for estimating the focus position. Currently, the approximate location of the lesion is usually estimated clinically by endobronchial ultrasound microprobe combined with ranging (REBUS-D) or guided sheath (REBUS-GS).

Generally, the ultrasonic microprobe combined distance measurement method combines a focus ultrasonic image and a bronchoscope lower bronchoscope clamp meatus, a bifurcation bronchus or other reference positions, extracts the ultrasonic microprobe to the corresponding position from the focus outwards, and measures the extracted distance of the microprobe by using a measuring tool (such as a ruler) outside the bronchoscope clamp meatus so as to estimate the focus distance position. The method can not quickly and intuitively define the position of the focus, and the examination operation is complex and tedious, which is not beneficial to shortening the operation time.

When the little probe of supersound jointly guides the sheath pipe to use, guide the sheath pipe and can lead to bronchoscope flexion stiff usually, it is less relatively to acquire pathological tissue sample simultaneously, guides the pipe in addition and belongs to disposable consumptive material, and the price is high.

Therefore, a simple and easy-to-use and low-cost means for locating the lesion site is urgently needed in clinic.

Disclosure of Invention

In view of the above, an object of the present invention is to provide an ultrasound microprobe, an ultrasound endoscopy system provided with the ultrasound microprobe, and a biopsy sampling system using a biopsy forceps in combination with the ultrasound endoscopy system, in which a distance scale is disposed on a catheter of the ultrasound microprobe, so that a doctor can conveniently and intuitively determine a lesion position in an endoscope view field, and provide precise positioning guidance for subsequent biopsy sampling.

In order to achieve the purpose, the invention provides the following technical scheme:

the ultrasonic microprobe comprises an ultrasonic transducer, a driving shaft and a catheter, wherein the driving shaft is connected with the ultrasonic transducer, the ultrasonic transducer is installed in the catheter, a plurality of positioning marks are axially arranged on the outer side surface of a far-end pipe section of the catheter, and a preset distance larger than zero is reserved between every two adjacent positioning marks.

Optionally, in the above ultrasonic microprobe, the positioning mark is a coating structure having a preset shape;

or the positioning mark is a convex structure with a section in a preset shape;

or the positioning mark is a groove structure with a preset cross section.

Optionally, in the ultrasonic microprobe, the preset shape is an arc line, and a plane of the arc line is perpendicular to a central axis of the catheter;

or the preset shape is a circular line perpendicular to the central axis of the conduit;

or, the preset shape is a polygonal pattern;

or the preset shape is an annular pattern formed by sequentially arranging a plurality of figures in an annular array along the circumferential direction of the conduit.

Optionally, in the above-mentioned ultrasound microprobe, every N positioning marks are grouped in a direction gradually approaching to the proximal end from the distal end of the catheter, N is a natural number greater than zero, and one positioning mark farthest from the distal end (i.e., the tip end) of the catheter in each group is different in size or shape from the other positioning marks.

Optionally, in the above-mentioned ultrasound microprobe, N is 2, or N is 3, or N is 5.

Optionally, in the above-mentioned ultrasound microprobe, starting from the distal end of the catheter, in a direction gradually approaching to the proximal end, every X of the positioning marks are grouped, X being a natural number greater than zero, wherein: the positioning marks in the same group have the same shape and the same size, and the positioning marks in different groups have different shapes or different sizes or different shapes and sizes.

Optionally, in the ultrasound microprobe, the positioning mark closest to the tip end of the catheter among the plurality of positioning marks is a start mark, and the start mark is located outside a tube segment for fixing the ultrasound transducer in the catheter.

An ultrasonic endoscopy system comprising an endoscope and an ultrasonic microprobe as described hereinabove, wherein an insertion end of a body of the endoscope is provided with an objective lens and a channel exit for protruding the catheter.

A biopsy sampling system comprising a biopsy forceps, and an endoultrasound system as described above.

In the ultrasonic microprobe, the ultrasonic endoscope inspection system and the biopsy sampling system, the distance scale is arranged on the far-end pipe section of the catheter of the ultrasonic microprobe, so that a doctor can conveniently and accurately and visually determine the position of a focus under the visual field of an endoscope, accurate positioning guidance is provided for subsequent biopsy sampling, the problem that the clinical pain point of the focus cannot be quickly and visually positioned at present is solved, the clinical inspection operation is simplified, the cost of clinical consumables is reduced, and the operation time is shortened.

Drawings

In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to the drawings without creative efforts.

FIG. 1 is a partial schematic structural view of an ultrasonic microprobe provided according to a first embodiment of the present invention, as it extends out of an instrument channel exit of an endoscope;

FIG. 2 is a schematic structural diagram of an ultrasonic microprobe in an endoscopic field of view according to a first embodiment of the present invention;

fig. 3 is a schematic structural diagram of an ultrasonic microprobe according to a first embodiment of the present invention;

FIG. 4 is a schematic structural diagram of an ultrasound microprobe according to a second embodiment of the present invention;

fig. 5 is a schematic structural diagram of an ultrasound microprobe according to a third embodiment of the present invention.

Wherein:

1-i.e., ultrasound transducer, 2-catheter, 3-drive shaft,

4-an objective lens, 5-an endoscope,

20-positioning the marker.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

First embodiment

Referring to fig. 1 to 3, a first embodiment of the present invention provides an ultrasonic microprobe and an ultrasonic endoscopy system provided with the ultrasonic microprobe.

The ultrasonic microprobe comprises an ultrasonic transducer 1, a driving shaft 3 and a catheter 2, wherein the driving shaft 3 is connected with the ultrasonic transducer 1, and the ultrasonic transducer 1 is arranged in the catheter 2. Wherein, a plurality of positioning marks 20 are arranged on the outer side surface of the far end pipe section of the catheter 2 along the axial direction, and the plurality of positioning marks 20 form a distance scale. In the distance scale, adjacent positioning marks 20 have a preset distance greater than zero, and the preset distance is preferably set to be 2mm, or 3mm, or 5mm, or 10mm, or 15mm, or other suitable parameters set according to actual needs.

The ultrasonic endoscopy system comprises an endoscope 5 and the ultrasonic microprobe. Wherein: the body insertion end of the endoscope 5 is provided with an objective 4 and a channel exit 6 for protruding the catheter 2, which channel exit 6 is the exit of the instrument channel inside the endoscope 5. Specifically, the system for ultrasonic endoscopy refers to the whole related system for microprobe examination, and includes not only the endoscope 5 and the ultrasonic microprobe, but also the whole system of the endoscope in which the endoscope 5 is located and the whole system of the microprobe in which the ultrasonic microprobe is located, wherein the microprobe is excited by the imaging system, and the microprobe and the imaging system are used in cooperation to produce an image. The whole endoscope system and the imaging system are all systems conventionally used in the field, and therefore, the detailed description thereof is omitted.

Here, it should be noted that: the 'endoscope body insertion end of the endoscope 5' refers to the end of the endoscope body inserted into the cavity in the operation process, and is generally provided with an objective lens 4 and a channel outlet 6, and according to different product requirements, an illuminating device, an air outlet pipe orifice and the like can be arranged; by "distal segment of the catheter 2" is meant the segment of the catheter 2 which, in operation, extends outside the channel outlet 6, within which the ultrasound transducer 1 operates and which is connected to the proximal end of the ultrasound microprobe by the drive shaft 3.

Taking the example of performing the intracavity ultrasound examination on the bronchus, the operation process of the ultrasound endoscopy system in the actual clinical use process is as follows:

s1: the distal end of the endoscope 5 is inserted into the bronchial lumen to be close to the site to be examined.

S2: the ultrasonic microprobe is inserted through an instrument channel in the endoscope 5.

S3: according to the approximate position of suspicious lesion shown in a chest CT image or in combination with auxiliary guiding means such as an electronic navigation bronchoscope system and the like, the ultrasonic microprobe is guided to be initially positioned until the ultrasonic microprobe confirms that the corresponding lesion is observed, and according to a distance scale on the catheter 2, the relative position and the distance between the distal lesion and a reference position (such as an endoscope jaw opening, a bronchial bifurcation or other reference positions) can be visually determined under the visual field of the objective lens 4. For example, referring to fig. 2, the distance d between the lesion position and the reference position in the field of view of the objective lens 4 can be measured directly by a distance scale on the catheter 2.

S4: finally, the biopsy forceps or the cell brush or other sampling instruments are guided to be accurately positioned at the focus position according to the focus position and the distance d obtained in the process, so that the focus can be quickly and accurately positioned. Taking the biopsy sampling process as an example, the sampling process is as follows: the biopsy forceps are firstly sent to the reference position, and then the biopsy forceps are moved forward by the distance d, so that the position of the biopsy forceps at the moment can be determined to be the focus position.

It can be seen that, because the distance scale is arranged on the far-end pipe section of the catheter 2 in the ultrasonic endoscope inspection system, a doctor can conveniently and accurately and visually determine the focus position under the endoscope visual field, so that the biopsy forceps or the cell brush or other instruments can be conveniently and accurately guided and positioned to the focus position subsequently, the problem that the clinical pain point of the focus cannot be quickly and visually positioned at present is solved, the clinical inspection operation is simplified, the cost of clinical consumables is reduced, and the operation time is shortened.

Moreover, when the ultrasonic microprobe is used for carrying out intracavity ultrasonic examination, a guide sheath tube is not needed, so that the cost is saved, and the problems that the bent part of the bronchoscope is rigid, the pathological tissue specimen is relatively small and the like caused by the guide sheath tube can be avoided.

Specifically, of the plurality of positioning marks 20, the positioning mark 20 closest to the tip end (i.e., the distal end) of the catheter 2 is a start mark, and the start mark is located outside a tube segment for fixing the ultrasound transducer 1 in the catheter 2. See in particular fig. 1 to 3.

Specifically, the positioning mark 20 may be a coating structure having a predetermined shape provided on the catheter 2, or the positioning mark 20 may be a protrusion structure having a predetermined shape provided on the catheter 2, or the positioning mark 20 may be a groove structure having a predetermined shape provided on the catheter 2. The "preset shape" may be an arc line (a plane where the arc line is located is perpendicular to the central axis of the catheter 2), or may be a circular line perpendicular to the central axis of the catheter 2, or, in a specific embodiment, the distance scale may be formed by arranging the arc-line-shaped positioning marks 20 and the circular-line-shaped positioning marks 20 at intervals.

Specifically, the plurality of positioning marks 20 are evenly arranged in the axial direction of the catheter 2. Among the plurality of positioning marks 20, the positioning mark 20 closest to the tip end of the catheter 2 is a first positioning mark, and the position of the first positioning mark is the position of the ultrasound transducer 1. Each position point of the catheter 2 in the endoscope field of view has a function of measurement positioning. The zero point position of the distance scale is set at the position where the ultrasonic transducer 1 is located.

To further optimize the above embodiment, starting from the distal end of the catheter 2, in the direction of the gradually approaching proximal end, every N positioning markers 20 are grouped, N being a natural number greater than zero, for example, N-2, or N-3, or N-5, or other values. Also, in each set of positioning marks 20, the one positioning mark 20 farthest from the tip (i.e., distal end) of the catheter 2 is different in size or shape from the other positioning marks 20 for easy visual counting.

Specifically, as shown in fig. 3, 10 circular ring-shaped positioning marks 20 with a distance of 1cm are arranged on the catheter 2, the position of the ultrasonic transducer 1 is the zero point position of the distance scale, and from the zero point position, the 5 th positioning mark 20 and the positioning marks 20 at the integral multiple positions of 5 are thickened lines, so as to be convenient for quick and intuitive distinguishing and counting; the positioning marks 20 at other positions are thin lines.

Second embodiment

The second embodiment of the present invention provides an ultrasonic microprobe, which is different from the ultrasonic microprobe provided in the first embodiment of the present invention only in that: each positioning marker 20 on the catheter 2 is a polygonal symbol, and, starting from the distal end of the catheter 2, in a direction gradually approaching towards the proximal end, every X positioning markers 20 are grouped, X being a natural number greater than zero, preferably X being 3, or alternatively X being 5, or another value. Wherein: the positioning marks 20 in the same group have the same shape and size, and the positioning marks 20 in different groups have different shapes or sizes or both shapes and sizes, so as to facilitate observation and counting. For example, referring to fig. 4, the first set of positioning marks 20 are all rectangular symbols, and the second set of positioning marks 20 are all triangles. However, the positioning mark 20 may be designed as a circle, a star, a flower, or other patterns in other embodiments.

Third embodiment

Referring to fig. 5, a third embodiment of the present invention provides an ultrasound microprobe, which is different from the ultrasound microprobe provided in the second embodiment of the present invention only in that: each positioning mark 20 is an annular pattern formed by sequentially arranging a plurality of patterns in an annular array along the circumferential direction of the catheter 2, so that the positioning marks 20 can be observed in different angular directions, and the positioning marks 20 can be observed under the condition that the catheter 2 is twisted.

Finally, it should be noted that in different embodiments, even on the same catheter 2 in the same embodiment, the positioning mark 20 can be formed by various processing methods, and the positioning mark 20 can be designed into various structures or shapes, as long as it is ensured that the normal transmission of the ultrasonic wave is not affected and the ultrasonic wave can be clearly observed in the endoscope view.

Third embodiment

In a third embodiment, the present invention provides a biopsy sampling system comprising a biopsy forceps or a cell brush or other sampling device, and an endoultrasound system as provided in any of the above embodiments.

Finally, it should also be noted that, herein, relational terms such as first and second, and the like may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus. Without further limitation, an element defined by the phrase "comprising an … …" does not exclude the presence of other identical elements in a process, method, article, or apparatus that comprises the element.

The embodiments in the present description are described in a progressive manner, each embodiment focuses on differences from other embodiments, and the same and similar parts among the embodiments are referred to each other.

The previous description of the disclosed embodiments is provided to enable any person skilled in the art to make or use the present invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the generic principles defined herein may be applied to other embodiments without departing from the spirit or scope of the invention. Thus, the present invention is not intended to be limited to the embodiments shown herein but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.

Claims (9)

1. The ultrasonic microprobe is characterized by comprising an ultrasonic transducer (1), a driving shaft (3) and a catheter (2), wherein the driving shaft (3) is connected with the ultrasonic transducer (1), the ultrasonic transducer (1) is installed in the catheter (2), a plurality of positioning marks (20) are axially arranged on the outer side surface of a far-end pipe section of the catheter (2), and a preset distance larger than zero is reserved between every two adjacent positioning marks (20).

2. The ultrasound microprobe of claim 1, wherein the positioning mark (20) is a coating structure having a preset shape;

or the positioning mark (20) is a convex structure with a preset cross section;

or the positioning mark (20) is a groove structure with a preset cross section.

3. The ultrasound microprobe according to claim 2, wherein the predetermined shape is an arc-shaped line, and a plane of the arc-shaped line is perpendicular to a central axis of the catheter (2);

or the preset shape is a circular line perpendicular to the central axis of the conduit (2);

or, the preset shape is a polygonal pattern;

or the preset shape is an annular pattern formed by sequentially arranging a plurality of figures in an annular mode along the circumferential direction of the guide pipe (2).

4. The ultrasound microprobe according to any one of claims 1 to 3, wherein every N positioning marks (20) are grouped in a direction gradually approaching proximally from the distal end of the catheter (2), N being a natural number greater than zero, and one positioning mark (20) farthest from the distal end of the catheter (2) in each group of the positioning marks (20) is different in size or shape from the other positioning marks (20).

5. The ultrasound microprobe of claim 4, wherein N-2, or N-3, or N-5.

6. The ultrasound microprobe according to any one of claims 1 to 3, wherein every X number of the positioning marks (20) is a group in a direction gradually approaching to a proximal end from a distal end of the catheter (2), X being a natural number greater than zero, wherein: the positioning marks (20) in the same group are the same in shape and size, and the positioning marks (20) in different groups are different in shape or size or both.

7. The ultrasound microprobe according to claim 1, wherein, of the plurality of positioning marks (20), the positioning mark (20) closest to the tip end of the catheter (2) is a start mark, the start mark being located outside a tube section for fixing the ultrasound transducer (1) in the catheter (2).

8. An endoultrasound inspection system, comprising an endoscope (5), and an ultrasound microprobe according to any one of claims 1 to 7, wherein a body insertion end of the endoscope (5) is provided with an objective lens (4) and a channel exit (6) for protruding the ultrasound microprobe.

9. A biopsy sampling system comprising a biopsy forceps or cell brush, and an ultrasound endoscopy system of claim 8.

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