CN112594999A - Control method, system and equipment for chemical refrigeration drug transfer box - Google Patents

Control method, system and equipment for chemical refrigeration drug transfer box Download PDF

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Publication number
CN112594999A
CN112594999A CN202011344962.0A CN202011344962A CN112594999A CN 112594999 A CN112594999 A CN 112594999A CN 202011344962 A CN202011344962 A CN 202011344962A CN 112594999 A CN112594999 A CN 112594999A
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China
Prior art keywords
temperature
information
medicine
medicine storage
freezing
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CN202011344962.0A
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CN112594999B (en
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许波
曹婉雯
何燕
许重远
乔惠
康玲
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Southern Hospital Southern Medical University
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Southern Hospital Southern Medical University
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    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25DREFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
    • F25D11/00Self-contained movable devices, e.g. domestic refrigerators
    • F25D11/02Self-contained movable devices, e.g. domestic refrigerators with cooling compartments at different temperatures
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25DREFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
    • F25D29/00Arrangement or mounting of control or safety devices

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  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Combustion & Propulsion (AREA)
  • Physics & Mathematics (AREA)
  • Mechanical Engineering (AREA)
  • Thermal Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Devices That Are Associated With Refrigeration Equipment (AREA)
  • Cold Air Circulating Systems And Constructional Details In Refrigerators (AREA)

Abstract

The invention discloses a control method, a system and equipment of a chemical refrigeration drug transfer box, wherein the method comprises the following steps: acquiring first temperature information of the freezing compartment, second temperature information of the medicine storage box and gravity information of the medicine storage box; generating temperature alarm information and medicine placement prompt information of the medicine storage box according to the second temperature information and the gravity information; and generating freezing grid replacement reminding information or medicine storage information according to the first temperature information. The invention can maintain the medicine storage temperature in the medicine storage box, improve the stability of the medicine storage environment temperature, and can be widely applied to the technical field of medical instruments.

Description

Control method, system and equipment for chemical refrigeration drug transfer box
Technical Field
The invention relates to the technical field of medical instruments, in particular to a control method, a system and equipment for a chemical refrigeration drug transfer box.
Background
The drug clinical test refers to any systematic research of drugs in human bodies, and is vital to monitoring the temperature of the test drugs in the whole process of the drug clinical test, and the temperature of the test drug in the processes of transportation, transportation and storage needs to be recorded in detail in each drug clinical test, so that the environment where the test drug is located is always in a specified temperature range, and the safety, stability and effectiveness of the drug are ensured. Particularly, test drugs (such as insulin glargine injection, adalimumab, infliximab and the like) stored at low temperature always need to be placed in an environment with the temperature of 2-8 ℃.
At present, a lot of test medicines are centrally managed, all the test medicines are uniformly placed in a central pharmacy of a clinical medicine testing institution, when the test medicines are used, a researcher takes the test medicines from the central pharmacy and transfers the test medicines to a department for a subject to use, and a common method is that the medicines are firstly placed in an insulation box or a foam box with a heat insulation effect, and then a plurality of ice blocks or ice bags are placed in the medicines and the insulation box. If the ice blocks in the heat preservation box are placed too little, the test drugs in the heat preservation box are easy to exceed the specified storage temperature of the drugs due to the long transportation distance, especially in hot summer in the south, and the outdoor temperature is high; if the ice blocks are excessively placed in the heat preservation box, the test medicine contacts the ice blocks, so that the temperature of the medicine is lower than the specified storage temperature of the medicine, and the phenomenon of medicine overtemperature occurs. According to the regulation of the clinical trial administration of the medicine, once the medicine is over-temperature, the medicine can not be delivered to the testee for use, and the testee participating in the clinical trial of the medicine can not take the medicine on time, thus seriously affecting the clinical trial process.
Disclosure of Invention
In view of this, embodiments of the present invention provide a method, a system, and an apparatus for controlling a chemical refrigeration drug transfer box, so as to improve the stability of the temperature of the drug storage environment.
The invention provides a control method of a chemical refrigeration drug transfer box, which comprises the following steps:
acquiring first temperature information of the freezing compartment, second temperature information of the medicine storage box and gravity information of the medicine storage box;
generating temperature alarm information and medicine placement prompt information of the medicine storage box according to the second temperature information and the gravity information;
and generating freezing grid replacement reminding information or medicine storage information according to the first temperature information.
In some embodiments, generating temperature alarm information and medicine placement prompt information of the medicine storage box according to the second temperature information and the gravity information includes:
when the second temperature information is higher than the temperature of the medicine storage tank and the gravity information is not changed, displaying an alarm prompt for reducing the temperature of the medicine storage tank and a prompt message for not placing the medicine through a display;
when the second temperature information is higher than the temperature for storing the medicine and the gravity information is increased, displaying a prompt for checking foreign matters in the medicine storage box, an alarm prompt for reducing the temperature of the medicine storage box and a prompt message for not placing the medicine by a display;
and when the second temperature information is in the temperature range for storing the medicines and the gravity information is not changed, displaying prompt information for placing the medicines by a display.
In some embodiments, the method further comprises:
and generating temperature information in the medicine storage tank, the starting time of the medicine placement and the duration information of the medicine placement according to the first temperature information.
In some embodiments, the method further comprises:
work as the second temperature information is in the temperature range that the medicine was stored, just gravity information takes place to increase, acquires the temperature information of freezing check in real time through the temperature-sensing ware, acquires the gravity information of medicine bin and the temperature-sensing ware through the medicine bin in real time through the gravity-sensing ware in real time acquires the temperature information of medicine bin.
In some embodiments, the method further comprises:
when the temperature of the medicine storage tank is reduced to a preset lower storage temperature limit value,
the freezing grids and the reactor are taken out through the prompt of a display;
sending out a flicker prompt through a signal lamp of the freezing grid;
the flash prompt is sent out by a signal lamp of the reactor.
In some embodiments, the method further comprises:
when the temperature of the medicine storage tank is increased to a preset upper limit value of the storage temperature,
controlling water in the freezing grids to flow into the reactor to generate a refrigeration reaction;
controlling the signal lamp of the freezing grid to be normally on;
the number of the freezing compartment in which the temperature is increased to the upper limit value of the storage temperature is displayed through the display, and the number of the reactor into which the water in the freezing compartment is to flow is displayed.
In some embodiments, the method further comprises:
when the temperature of the medicine storage tank is increased to a preset upper limit value of the storage temperature,
acquiring gravity information of the medicine storage tank through a gravity sensor;
determining that the medicine is stored in the medicine storage tank when the gravity of the medicine storage tank increases;
determining that the drug is removed from the drug storage bin when the weight of the drug storage bin is reduced;
the time of drug withdrawal, the temperature of drug withdrawal, and the start time of drug withdrawal were recorded.
A second aspect of the invention provides a control system for a chemically-refrigerated drug transfer cassette, comprising:
the acquisition module is used for acquiring first temperature information of the freezing grid, second temperature information of the medicine storage box and gravity information of the medicine storage box;
the first generation module is used for generating temperature alarm information and medicine placement prompt information of the medicine storage box according to the second temperature information and the gravity information;
and the second generation module is used for generating freezing grid replacement reminding information or medicine storage information according to the first temperature information.
The invention provides a control system of a chemical refrigeration drug transfer box, which comprises an insulation can, a drug storage box, a connector, a freezing grid, a reactor, a signal processing system, a gravity sensor, a temperature sensor, an information storage, a power supply, a display screen and a signal lamp, wherein the insulation can is arranged in the drug storage box;
the temperature sensor is respectively positioned in the heat insulation box and the medicine storage box, and the output end of the temperature sensor is connected with the input end of the signal processing system;
the gravity sensor is positioned on the partition plate, and the output ends of the gravity sensors are connected with the input end of the signal processing system;
the signal lamp consists of a freezing grid signal lamp and a reactor signal lamp, and the signal lamps are respectively positioned on the side wall of the heat-insulation box and the cover of the heat-insulation box;
the output end of the signal processing system is respectively connected with the input ends of the electric switch, the signal lamp and the display screen, and the power supply is respectively connected with the signal lamp, the signal processing system, the electric switch, the gravity sensor, the temperature sensor, the information storage and the display screen.
A fourth aspect of the invention provides an electronic device comprising a processor and a memory;
the memory is used for storing programs;
the processor executes the program to implement the method as described above.
After acquiring first temperature information of the freezing compartment, second temperature information of the medicine storage box and gravity information of the medicine storage box; generating temperature alarm information and medicine placement prompt information of the medicine storage box according to the second temperature information and the gravity information; generating freezing grid replacement reminding information or medicine storage information according to the first temperature information; the invention can maintain the medicine storage temperature in the medicine storage box and improve the stability of the medicine storage environment temperature.
Drawings
In order to more clearly illustrate the technical solutions in the embodiments of the present application, the drawings needed to be used in the description of the embodiments are briefly introduced below, and it is obvious that the drawings in the following description are only some embodiments of the present application, and it is obvious for those skilled in the art to obtain other drawings based on these drawings without creative efforts.
FIG. 1 is a schematic diagram of a chemically refrigerated drug transfer cassette provided in an embodiment of the present invention;
fig. 2 is a schematic overall flow chart of a control method of a drug transfer box according to an embodiment of the present invention.
Detailed Description
In order to make the objects, technical solutions and advantages of the present application more apparent, the present application is described in further detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the present application and are not intended to limit the present application.
The embodiment of the invention provides a control method of a chemical refrigeration drug transfer box, which comprises the following steps of:
acquiring first temperature information of the freezing compartment, second temperature information of the medicine storage box and gravity information of the medicine storage box;
generating temperature alarm information and medicine placement prompt information of the medicine storage box according to the second temperature information and the gravity information;
and generating freezing grid replacement reminding information or medicine storage information according to the first temperature information.
In some embodiments, generating temperature alarm information and medicine placement prompt information of the medicine storage box according to the second temperature information and the gravity information includes:
when the second temperature information is higher than the temperature of the medicine storage tank and the gravity information is not changed, displaying an alarm prompt for reducing the temperature of the medicine storage tank and a prompt message for not placing the medicine through a display;
when the second temperature information is higher than the temperature for storing the medicine and the gravity information is increased, displaying a prompt for checking foreign matters in the medicine storage box, an alarm prompt for reducing the temperature of the medicine storage box and a prompt message for not placing the medicine by a display;
and when the second temperature information is in the temperature range for storing the medicines and the gravity information is not changed, displaying prompt information for placing the medicines by a display.
In some embodiments, the method further comprises:
and generating temperature information in the medicine storage tank, the starting time of the medicine placement and the duration information of the medicine placement according to the first temperature information.
In some embodiments, the method further comprises:
work as the second temperature information is in the temperature range that the medicine was stored, just gravity information takes place to increase, acquires the temperature information of freezing check in real time through the temperature-sensing ware, acquires the gravity information of medicine bin and the temperature-sensing ware through the medicine bin in real time through the gravity-sensing ware in real time acquires the temperature information of medicine bin.
In some embodiments, the method further comprises:
when the temperature of the medicine storage tank is reduced to a preset lower storage temperature limit value,
the freezing grids and the reactor are taken out through the prompt of a display;
sending out a flicker prompt through a signal lamp of the freezing grid;
the flash prompt is sent out by a signal lamp of the reactor.
In some embodiments, the method further comprises:
when the temperature of the medicine storage tank is increased to a preset upper limit value of the storage temperature,
controlling water in the freezing grids to flow into the reactor to generate a refrigeration reaction;
controlling the signal lamp of the freezing grid to be normally on;
the number of the freezing compartment in which the temperature is increased to the upper limit value of the storage temperature is displayed through the display, and the number of the reactor into which the water in the freezing compartment is to flow is displayed.
In some embodiments, the method further comprises:
when the temperature of the medicine storage tank is increased to a preset upper limit value of the storage temperature,
acquiring gravity information of the medicine storage tank through a gravity sensor;
determining that the medicine is stored in the medicine storage tank when the gravity of the medicine storage tank increases;
determining that the drug is removed from the drug storage bin when the weight of the drug storage bin is reduced;
the time of drug withdrawal, the temperature of drug withdrawal, and the start time of drug withdrawal were recorded.
The embodiment of the invention also provides a control system of the chemical refrigeration drug transfer box, which comprises the following components:
the acquisition module is used for acquiring first temperature information of the freezing grid, second temperature information of the medicine storage box and gravity information of the medicine storage box;
the first generation module is used for generating temperature alarm information and medicine placement prompt information of the medicine storage box according to the second temperature information and the gravity information;
and the second generation module is used for generating freezing grid replacement reminding information or medicine storage information according to the first temperature information.
The embodiment of the invention also provides a control system of the chemical refrigeration drug transfer box, which comprises an insulation can, a drug storage box, a connector, a freezing grid, a reactor, a signal processing system, a gravity sensor, a temperature sensor, an information storage, a power supply, a display screen and a signal lamp;
the temperature sensor is respectively positioned in the heat insulation box and the medicine storage box, and the output end of the temperature sensor is connected with the input end of the signal processing system;
the gravity sensor is positioned on the partition plate, and the output ends of the gravity sensors are connected with the input end of the signal processing system;
the signal lamp consists of a freezing grid signal lamp and a reactor signal lamp, and the signal lamps are respectively positioned on the side wall of the heat-insulation box and the cover of the heat-insulation box;
the output end of the signal processing system is respectively connected with the input ends of the electric switch, the signal lamp and the display screen, and the power supply is respectively connected with the signal lamp, the signal processing system, the electric switch, the gravity sensor, the temperature sensor, the information storage and the display screen.
The embodiment of the invention also provides the electronic equipment, which comprises a processor and a memory;
the memory is used for storing programs;
the processor executes the program to implement the method as described above.
Specifically, in order to implement the control method of the drug delivery box, referring to fig. 1, an embodiment of the present invention provides a chemically refrigerated drug delivery box.
The embodiment of the invention provides a chemical refrigeration drug transfer box, which comprises: incubator 1, medicine case 2, connector 8, freezing check 37, reactor 17, signal processing system 14, gravity inductor 16, temperature-sensing ware, information memory 15, power 19, display screen 29, signal lamp.
The drug storage box 2, the connector 8, the freezing grid 37 and the reactor 17 are arranged in the heat preservation box 1, the connector 8 is connected with the freezing grid 37 and the reactor 17 respectively, the temperature sensor is composed of a heat preservation box temperature sensor 36 and a drug storage box temperature sensor 18, the temperature sensors are located in the heat preservation box and the drug storage box respectively, and the output end of the temperature sensor is connected with the input end of the signal processing system 14. The gravity sensor 16 is positioned on the partition plate 12, the output end of the gravity sensor 16 is connected with the input end of the signal processing system 14, the signal lamp consists of a freezing grid signal lamp 33 and a reactor signal lamp 23, and the signal lamps are respectively positioned on the side wall of the heat-insulation box and the cover 42 of the heat-insulation box; the output end of the signal processing system 14 is respectively connected with the input ends of the electric switch 9, the signal lamp and the display screen 29, and the power supply 19 is respectively connected with the signal lamp, the signal processing system 14, the electric switch 9, the gravity sensor 16, the temperature sensor, the information storage 15 and the display screen 29;
further, insulation can 1 is hollow cuboid, insulation can 1 is used for placing medicine and deposits case 2, insulation can 1 has the heat preservation effect, insulation can 1 is bilayer structure, it has heat preservation material, like polyurethane foam to fill in insulation can 1 intermediate layer.
Furthermore, the outer side wall of the heat preservation box 1 is made of hard and wear-resistant plastic or metal materials, so that the heat preservation effect is prevented from being influenced after the outer side wall of the heat preservation box 1 is broken due to abrasion in the use process of the heat preservation box 1. The outer side of the heat preservation box 1 is provided with a lock catch 25, and the lock catch 25 is used for closing the heat preservation box.
Furthermore, a plurality of brackets 38 are arranged on the inner side wall of one side of the heat insulation box 1, and the brackets 38 enable a gap to be formed between the medicine storage box 2 and the heat insulation box 1. A freezing compartment 37 can be placed between two adjacent brackets 38, and an operator can place several freezing compartments 37 in the thermal box 1.
Furthermore, a plurality of incubator temperature sensors 36 are arranged on the inner side wall of the incubator 1, a corresponding incubator temperature sensor 36 is arranged between each freezing grid 37 and the incubator 1, and the incubator temperature sensors 36 are used for sensing the temperature of the freezing grids 37 and transmitting the temperature signals to the signal processing system 14. The output end of the temperature sensor 36 of the heat preservation box is connected with the input end of the signal processing system 14.
Further, the freezing lattices 37 are positioned between the medicine storage box 2 and the heat insulation box 1, the freezing lattices 37 are closed cuboids, the width of each freezing lattice 37 is slightly smaller than the distance between the two adjacent brackets 38, and the thickness of each freezing lattice 37 is slightly smaller than the distance between the medicine storage box 2 and the heat insulation box 1. The freezing grid 37 is made of a hard material (such as organic glass, plastic, metal, and the like) with good heat conduction, and a freezing medium is filled in the freezing grid 37, wherein the freezing medium can be water or physiological saline with a lower freezing point.
Further, freezing check handle 34 is arranged on the top of freezing check 37, freezing check handle 34 is used for taking freezing check 37, and a spring is arranged between freezing check handle 34 and freezing check 37. Depressing or releasing the spring allows the freezer handle 34 to expand and contract.
Further, a spring valve 39 is arranged at the bottom of the freezing compartment 37. When pressed, the spring valve 39 is opened and the freezing medium in the freezing compartment 37 can flow out.
Further, the spring valve 39 is composed of a piston 40 and a support plate 6, and a spring is arranged between the piston 40 and the support plate 6. When the support plate 6 is pressed, the spring is compressed and the piston 40 moves upward. The freezing medium in the freezing compartment 37 flows out from below the piston 40.
Further, freezing check 37 outside has freezing check barb 3 of a plurality of, freezing check barb 3 is triangle-shaped, freezing check barb 3 is close to freezing check 37 bottom, freezing check barb 3 and 4 one-to-one of connector interface barb. The bottom of the freezing compartment 37 is connected to the connector inlet 5.
Further, the connectors 8 are located below the freezing compartments 37, one connector 8 for each freezing compartment 37. The connector 8 is located on one side of the reactor 17. The connector 8 consists of a connector inlet 5, a filter plate 7, a connector outlet 10 and an electric switch 9.
Further, the connector inlet 5 is connected to the bottom of the freezing compartment 37. A perforated filter plate 7 is provided in the connector inlet 5, said filter plate 7 being adapted to filter the freezing medium entering the connector 8.
Further, the inside wall of connector entry 5 has a plurality of connector interface barb 4, connector interface barb 4 is triangle-shaped, freezing check barb 3 and 4 one-to-one of connector interface barb. During the use, freezing check 37 passes through freezing check barb 3 and fixes at connector entry 5, continues to press down again, and after the last pressure backup pad 6 of spring valve contacted filter 7, the spring was compressed, and piston 40 moved upwards. The freezing medium in the freezing compartment 37 flows out from below the piston 40. The freezing medium flows from the holes in the middle of the filter plate 7 into the connector inlet 5.
Further, the electric switch 9 is located between the connector inlet 5 and the connector outlet 10. When the electric switch 9 is turned on, the connector inlet 5 communicates with the connector outlet 10, and when the electric switch 9 is turned off, the connector inlet 5 does not communicate with the connector outlet 10. The input of the electric switch 9 is connected to a signal processing system 14.
Further, the connector outlet 10 is connected to one side of the reactor 17, and when the electric switch 9 is turned on, the connector inlet 5 is communicated with the connector outlet 10, and the refrigerant at the connector inlet is introduced into the reactor 17 through the connector outlet 10, one connector 8 corresponding to one reactor 17.
Further, the reactor 17 is positioned between the partition plate 12 and the bottom of the heat insulation box 1, the reactor 17 is a cuboid, the thickness of the reactor 17 is slightly smaller than the distance between the partition plate 12 and the bottom of the heat insulation box 1, and the width of the reactor 17 is substantially the same as that of the freezing grid 37. The length of the reactor 17 is slightly less than that of the bottom of the heat preservation box 1, and the reactor 17 is composed of a reactor handle 20, a storage grid 41 and a one-way valve 11. The reactor handle 20 is used for taking the freezing grids 37, a spring is arranged in the reactor handle 20, and the reactor handle 20 can be stretched by pressing or loosening the spring.
Further, the storage grid 41 is connected to the reactor handle 20, the storage grid 41 is made of a hard material (such as organic glass, metal, etc.) with good heat conduction, and a refrigerating substance (such as urea, nitrophosphate, or ammonium nitrate) which can perform an endothermic reaction when encountering water is placed in the storage grid 41. The one-way valve 11 is arranged on one side of the storage grid 41 close to the connector outlet 10, when the storage grid 41 is inserted into the connector outlet 10, the one-way valve 11 is opened, and the connector outlet 10 is communicated with the storage grid 41; when the reservoir 41 is pulled out of the connector outlet 10, the check valve 11 is closed, and when the substance in the reservoir 41 does not flow out of the check valve 11.
Furthermore, a plurality of reactor outlets 21 are arranged on the side wall of the heat preservation box 1. One reactor outlet 21 corresponds to one reactor 17, the reactor outlet 21 is substantially the same size as the reactor 17, and the reactor outlet 21 has a C-shaped groove.
Furthermore, there are reactor signal lamps 23 above the reactor outlets 21, each reactor outlet 21 corresponds to a reactor signal lamp 23, and the input end of the reactor signal lamp 23 is connected to the output end of the signal processing system 14.
Further, the reactor baffle 22 is located in the middle of the C-shaped groove of the reactor outlet 21, the reactor baffle 22 can move left and right on the reactor outlet 21, and the reactor baffle 22 is made of a hard material with a heat preservation effect, such as a double-layer vacuum metal plate or a plastic plate. The reactor baffle 22 is used for opening or closing the reactor outlet 21, when in use, the reactor 17 is placed in the insulation can 1 through the reactor outlet 21 and communicated with the connector outlet 10, the reactor baffle 22 closes the reactor outlet 21, and the spring of the reactor handle 20 is compressed, so that the reactor 17 is fixed on one side of the connector outlet 10; when the reactor 17 is taken out, the reactor baffle 22 is opened, the spring of the reactor handle 20 is extended, and the reactor 17 can be pulled out after the reactor handle 20 is protruded.
The cover 42 of the incubator box is provided with a freezing grid outlet 31, the freezing grid outlet 31 is arranged right above the freezing grid 37, the size of the freezing grid outlet 31 is basically the same as that of the freezing grid 37, and the freezing grid outlet 31 is provided with a C-shaped groove.
Furthermore, a freezing grid signal lamp 33 is arranged on the cover 42 of the incubator, each freezing grid outlet 31 corresponds to one freezing grid signal lamp 33, and the input end of each freezing grid signal lamp 33 is connected with the output end of the signal processing system 14.
The freezing check baffle 32 is located in the middle of the C-shaped groove of the freezing check outlet 31, the freezing check baffle 32 can move left and right on the freezing check outlet 31, and the freezing check baffle 32 is made of hard materials with heat preservation effect, such as a double-layer vacuum metal plate or a plastic plate. The freezing grid baffle 32 is used for opening or closing the freezing grid outlet 31, when the freezing grid baffle 32 is used, the freezing grid 37 is placed in the heat preservation box 1 through the freezing grid outlet 31 and communicated with the connector inlet 5, the freezing grid baffle 32 closes the freezing grid outlet 31, and the spring of the freezing grid handle 34 is compressed, so that the freezing grid 37 is fixed above the connector inlet 5; when the freezing compartment 37 is taken out, the freezing compartment baffle 32 is opened, the spring of the freezing compartment handle 34 is extended, and the freezing compartment 37 can be pulled out after the freezing compartment handle 34 is protruded.
Further, a display screen 29 is arranged on the cover 42 of the heat preservation box. The display screen 29 is used for displaying contents according to the control signal of the signal processing system 14, including the contents of the temperature and the variation curve in the heat preservation box 1 and the medicine storage box 2, the start and end time of the transferred medicine storage, and the like. The display screen 29 may be implemented using an existing touch display screen 29 that is connected to the signal processing system 14 via a general purpose I/O interface. In addition, the invention also obtains the input signal of the user through the touch display screen 29 and sends the input signal to the signal processing system 14.
Further, the partition plate 12 is positioned in the insulation can 1, and the partition plate 12 is positioned between the medicine storage box 2 and the reactor 17. The partition plate 12 is made of a hard material (such as organic glass, metal, etc.) with good heat conduction. When an endothermic chemical reaction occurs in the reactor 17, the low temperature in the reactor 17 can be conducted to the bottom of the medicine storage tank 2 through the partition 12.
Further, a gravity sensor 16 is disposed on the partition board 12. The gravity sensor 16 is used for sensing the gravity change of the medicine storage box 2. And conducts the gravity signal to the signal processing system 14. The output end of the gravity sensor 16 is connected with the input end of the signal processing system 14.
Further, the medicine storage box 2 is positioned in the heat insulation box 1, and the medicine storage box 2 is positioned above the partition plate 12. The medicine storage case 2 is composed of a case body 28 and a case cover 27.
Further, the box 28 is a hollow cuboid, the box 28 is a double-layer structure, and the hollow part of the box 28 is used for placing the transported drugs.
Further, the outer side wall of the box body 28 has a heat preservation effect, and a heat preservation material can be wrapped on the outer side of the box body 28, wherein the heat preservation material can be a combination of pearl wool and aluminum foil tinfoil (similar to a heat preservation bag used in daily life).
Further, the box 28 inside wall comprises stereoplasm and the good material of heat conductivity, the material of inlayer can be individual layer plastics, organic glass or metal material.
Further, the interlayer between the outer wall and the inner wall of the box 28 is filled with a buffer substance, which may be water or a sodium carboxymethyl cellulose (CMC-Na) solution.
Further, the inner side wall of the box body 28 is provided with a temperature sensor 18 of the medicine storage box. The drug storage bin temperature sensor 18 is used to sense the temperature at the bottom of the drug storage bin and to conduct a temperature signal to the signal processing system 14. The output end of the temperature sensor 18 of the medicine storage box is connected with the input end of the signal processing system 14.
Further, the box 28 has a magnet 26 at its upper edge. For adsorbing the tank cap 27.
Further, the cover 27 is located above the case 28. The box cover 27 is a double-layer structure, and the box cover 27 can be double-layer vacuum transparent organic glass. An operator can observe the condition of the transported medicine through the box cover 27, an iron sheet 30 is arranged on the inner side edge of the box cover 27, and the iron sheet 30 can enable the box cover 27 to be adsorbed on the magnet 26 of the box body 28.
Further, the signal processing system 14 is located at the bottom of the heat insulation box 1, and the signal processing system 14 is configured to trigger a corresponding control signal according to the gravity sensing signal sent by the gravity sensor 16 and the temperature sensing signal sent by the temperature sensor, and send the control signal to the display screen 29, the signal lamp, the connector 8, and the like. The signal processing system 14 of the present invention does not relate to the improvement of the data processing flow, and the signal triggering process can be implemented by using the existing MCU, which is not described herein again.
The information storage 15 is located at the bottom of the incubator 1 and is used for storing all data after the instrument is started.
The power supply 19 is positioned at the bottom of the heat preservation box 1, and the power supply 19 is used for providing the power supply 19 for the gravity sensor 16, the temperature sensor, the display screen 29, the electric switch 9, the signal lamp, the signal processing system 14 and the information storage 15. The power supply 19 is a reservoir type battery.
Furthermore, a pull rod 24 is arranged on the outer side wall of the heat preservation box 1, and the pull rod 24 is used for pulling the heat preservation box 1.
Furthermore, wheels 13 are arranged at the bottom of the incubator 1. The operator can conveniently pull the incubator 1.
When the medicine is transported, the heat preservation effect of the heat preservation box can effectively protect and maintain the environmental temperature of the medicine storage box, and when the temperature in the heat preservation box exceeds 8 ℃, the buffer substance with lower temperature in the medicine storage box can further maintain the medicine storage temperature, so that the medicine storage temperature is maintained between 2 ℃ and 8 ℃, and the medicine is prevented from being over-heated; when the temperature in the insulation can is lower than 2 ℃, the buffer substance in the medicine storage box absorbs the low temperature in the insulation can, and the low temperature in the insulation can is buffered to influence the temperature of the medicine stored in the storage box, so that the temperature of the medicine stored is maintained between 2 and 8 ℃, and the medicine is prevented from being over-heated; because the specific heat capacity of the buffer substance in the medicine storage box is large, the temperature of the buffer substance can rise or fall only after the buffer substance absorbs or releases a large amount of energy, the rise or fall of the temperature of the buffer substance can influence the environment temperature for storing the medicines, meanwhile, the heat insulation material on the outer side of the medicine storage box enables the buffer substance to be relatively isolated from the inner environment of the heat insulation box, and the rise or fall amplitude of the temperature of the buffer substance in the medicine storage box along with the change of the inner environment temperature of the heat insulation box is further reduced. Improve the buffering effect of the buffering substance and reduce the temperature difference change of the medicine storage environment. The stability of the temperature of the drug storage environment is improved; when the freezing grids and the reactor are put in or taken out and the endothermic chemical reaction occurs, the temperature in the medicine storage box is ensured not to be excessively higher or lower than the temperature for storing the medicine due to the buffer action of the heat insulation material at the outer side of the medicine storage box and the buffer material in the box body.
When the medicine is transported, the frozen freezing grids can be placed to maintain the low-temperature transportation environment in the heat preservation box, and when the frozen freezing grids can not maintain the low-temperature environment, the freezing medium in the freezing grids flows into the reactor to generate endothermic chemical reaction, so that the low-temperature environment is continuously maintained; or the freezing medium in the freezing grid can directly flow into the reactor to generate endothermic chemical reaction and maintain the low-temperature environment. The freezing grids and the reactors in the heat preservation box can be taken out, an operator can adjust the number of the freezing grids and the reactors in the device according to actual use requirements, and when the chemical refrigeration is carried out, the signal processing system preferentially flows the freezing medium in the freezing grids which is high in temperature or cannot continuously maintain the low-temperature environment into the reactors according to the temperature of each freezing grid sensed by the temperature sensor of the heat preservation box, so that the endothermic chemical reaction is carried out, and the low-temperature environment is maintained.
The used freezing grids and the reactor are updated in time, and then the freezing medium in the replaced freezing grids flows into the reactor to generate endothermic chemical reaction, so that the low-temperature environment can be maintained for a long time. The handle that can stretch out and draw back makes things convenient for the operator to take freezing check and reactor. The signal light may alert the operator to take a used freezer compartment and reactor.
The gravity sensor senses the gravity of the medicine storage box, and the signal processing system can judge the time for taking out the medicine storage box and putting in the medicine to be transported according to the gravity change of the medicine storage box.
The information storage stores all information in the use process, so that the operation is convenient to know whether the whole process of drug loading and transporting is over-temperature, the safety and the quality of the drug are ensured, and the drug taking safety of a subject is ensured.
The wheels at the bottom of the heat preservation box and the pull rods on the side walls facilitate the transfer of the medicine by an operator, and the practicability is high.
In the description herein, references to the description of the term "one embodiment," "some embodiments," "an example," "a specific example," or "some examples," etc., mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the invention. In this specification, the schematic representations of the terms used above do not necessarily refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.
While embodiments of the invention have been shown and described, it will be understood by those of ordinary skill in the art that: various changes, modifications, substitutions and alterations can be made to the embodiments without departing from the principles and spirit of the invention, the scope of which is defined by the claims and their equivalents.
While the preferred embodiments of the present invention have been illustrated and described, it will be understood by those skilled in the art that various changes in form and details may be made therein without departing from the spirit and scope of the invention as defined by the appended claims.

Claims (10)

1. A control method of a chemical refrigeration drug transfer box is characterized by comprising the following steps:
acquiring first temperature information of the freezing compartment, second temperature information of the medicine storage box and gravity information of the medicine storage box;
generating temperature alarm information and medicine placement prompt information of the medicine storage box according to the second temperature information and the gravity information;
and generating freezing grid replacement reminding information or medicine storage information according to the first temperature information.
2. The method for controlling a chemical refrigeration drug transfer box according to claim 1, wherein generating temperature alarm information and drug placement prompt information of a drug storage box according to the second temperature information and gravity information comprises:
when the second temperature information is higher than the temperature of the medicine storage tank and the gravity information is not changed, displaying an alarm prompt for reducing the temperature of the medicine storage tank and a prompt message for not placing the medicine through a display;
when the second temperature information is higher than the temperature for storing the medicine and the gravity information is increased, displaying a prompt for checking foreign matters in the medicine storage box, an alarm prompt for reducing the temperature of the medicine storage box and a prompt message for not placing the medicine by a display;
and when the second temperature information is in the temperature range for storing the medicines and the gravity information is not changed, displaying prompt information for placing the medicines by a display.
3. The method of controlling a chemically-refrigerated drug transport cassette of claim 1, further comprising:
and generating temperature information in the medicine storage tank, the starting time of the medicine placement and the duration information of the medicine placement according to the first temperature information.
4. The method of controlling a chemically-refrigerated drug transport cassette of claim 1, further comprising:
work as the second temperature information is in the temperature range that the medicine was stored, just gravity information takes place to increase, acquires the temperature information of freezing check in real time through the temperature-sensing ware, acquires the gravity information of medicine bin and the temperature-sensing ware through the medicine bin in real time through the gravity-sensing ware in real time acquires the temperature information of medicine bin.
5. The method of controlling a chemically-refrigerated drug transfer cassette of claim 4, further comprising:
when the temperature of the medicine storage tank is reduced to a preset lower storage temperature limit value,
the freezing grids and the reactor are taken out through the prompt of a display;
sending out a flicker prompt through a signal lamp of the freezing grid;
the flash prompt is sent out by a signal lamp of the reactor.
6. The method of controlling a chemically-refrigerated drug transfer cassette of claim 5, further comprising:
when the temperature of the medicine storage tank is increased to a preset upper limit value of the storage temperature,
controlling water in the freezing grids to flow into the reactor to generate a refrigeration reaction;
controlling the signal lamp of the freezing grid to be normally on;
the number of the freezing compartment in which the temperature is increased to the upper limit value of the storage temperature is displayed through the display, and the number of the reactor into which the water in the freezing compartment is to flow is displayed.
7. The method of controlling a chemically-refrigerated drug transfer cassette of claim 6, further comprising:
when the temperature of the medicine storage tank is increased to a preset upper limit value of the storage temperature,
acquiring gravity information of the medicine storage tank through a gravity sensor;
determining that the medicine is stored in the medicine storage tank when the gravity of the medicine storage tank increases;
determining that the drug is removed from the drug storage bin when the weight of the drug storage bin is reduced;
the time of drug withdrawal, the temperature of drug withdrawal, and the start time of drug withdrawal were recorded.
8. A control system for a chemically refrigerated drug transfer cassette, comprising:
the acquisition module is used for acquiring first temperature information of the freezing grid, second temperature information of the medicine storage box and gravity information of the medicine storage box;
the first generation module is used for generating temperature alarm information and medicine placement prompt information of the medicine storage box according to the second temperature information and the gravity information;
and the second generation module is used for generating freezing grid replacement reminding information or medicine storage information according to the first temperature information.
9. A control system of a chemical refrigeration drug transfer box is characterized by comprising an insulation box, a drug storage box, a connector, a freezing grid, a reactor, a signal processing system, a gravity sensor, a temperature sensor, an information storage, a power supply, a display screen and a signal lamp;
the temperature sensor is respectively positioned in the heat insulation box and the medicine storage box, and the output end of the temperature sensor is connected with the input end of the signal processing system;
the gravity sensor is positioned on the partition plate, and the output ends of the gravity sensors are connected with the input end of the signal processing system;
the signal lamp consists of a freezing grid signal lamp and a reactor signal lamp, and the signal lamps are respectively positioned on the side wall of the heat-insulation box and the cover of the heat-insulation box;
the output end of the signal processing system is respectively connected with the input ends of the electric switch, the signal lamp and the display screen, and the power supply is respectively connected with the signal lamp, the signal processing system, the electric switch, the gravity sensor, the temperature sensor, the information storage and the display screen.
10. An electronic device comprising a processor and a memory;
the memory is used for storing programs;
the processor executing the program realizes the method according to any one of claims 1-7.
CN202011344962.0A 2020-11-26 2020-11-26 Control method, system and equipment for chemical refrigeration drug transfer box Active CN112594999B (en)

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CN207751208U (en) * 2017-09-16 2018-08-21 成都老农王农业开发有限公司 A kind of cold storage plant of blueberry
CN210823384U (en) * 2020-03-02 2020-06-23 南方医科大学南方医院 Layered biomedical medicine storage box
CN211077044U (en) * 2019-08-01 2020-07-24 蔡海平 Portable liquid collecting device for medical treatment

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2032692U (en) * 1988-04-06 1989-02-15 黄巧珍 Portable refrigerator
CN2064484U (en) * 1989-11-15 1990-10-24 杨宗德 Chemical freezers
US5154067A (en) * 1990-04-12 1992-10-13 Matsushita Electric Industrial Co., Ltd. Portable cooler using chemical reaction
CN104272038A (en) * 2012-05-03 2015-01-07 科尔德维公司 Device and method for the continuous thermochemical production of cold
CN207751208U (en) * 2017-09-16 2018-08-21 成都老农王农业开发有限公司 A kind of cold storage plant of blueberry
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CN211077044U (en) * 2019-08-01 2020-07-24 蔡海平 Portable liquid collecting device for medical treatment
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