CN112515813A

CN112515813A - Artificial ligament

Info

Publication number: CN112515813A
Application number: CN202011383810.1A
Authority: CN
Inventors: 胡叶枫; 董超杰; 罗星宇; 陈晓颖
Original assignee: Huamu Medical Technology Shanghai Co ltd
Current assignee: Huamu Medical Technology Shanghai Co ltd
Priority date: 2020-12-01
Filing date: 2020-12-01
Publication date: 2021-03-19

Abstract

The invention relates to the technical field of human ligament repair, in particular to an artificial ligament which comprises an implantation section, a first fixed section and a second fixed section, wherein the first fixed section and the second fixed section are arranged at two ends of the implantation section, two ends of the implantation section are connected with the first fixed section and the second fixed section through a traction section, and the implantation section, the first fixed section and the second fixed section respectively comprise a fastening layer arranged in the center and a degradation protective layer wrapped on the outer side of the fastening layer. The degradable protective layer has the advantages of good hydrophilicity and biocompatibility, and the fastening layer wrapping the center of the degradable protective layer can effectively avoid the situation that the fastening layer is abraded in a human body and particles fall off to cause synovitis.

Description

Artificial ligament

Technical Field

The invention belongs to the technical field of human ligament repair, and particularly relates to an artificial ligament.

Background

Among the options for repairing ligaments are artificial ligaments and the body's own ligaments, which are not biocompatible because they are part of themselves but have the disadvantage of slow recovery and additional trauma at the site of ligament extraction. In the aspect of the artificial ligament, the artificial ligament of france LARS is mature on the market at present, polyethylene glycol terephthalate is used as the material, the polyethylene glycol terephthalate has good mechanical property, the situation that secondary ligament rupture is caused by movement after implantation is ensured, but the hydrophilicity of the polyethylene glycol terephthalate material is poor, the biocompatibility is not very good, biological tissues can not grow to the artificial ligament well after implantation, the ligament is recovered to a certain extent, and the situation that synovitis is caused by the fact that particles fall due to abrasion in a limiting mode exists.

Aiming at the problems, through search, the Chinese invention patent is as follows: a composite artificial ligament and a preparation method thereof (application number is 201310082756.0, application date is 2013-03-15), the application discloses a composite artificial ligament and a preparation method thereof, the composite artificial ligament has a rod-shaped structure, and the rod-shaped structure is formed by rolling a woven mesh; the weaving net is a net-shaped structure woven by wires, and the wires in the rod-shaped structure are entangled with each other and are cohered to form a mesh staggered structure; the thread is formed by winding a plurality of tows with different degradation performances, and the tows with different degradation performances are respectively formed by spinning or spinning components with different degradation performances, so that the obtained composite artificial ligament has gradient degradation performance. The composite artificial ligament has good mechanical property, can promote the attachment of surrounding tissues and the repair and normal growth of ligament tissues, can gradually biodegrade partial components in a body, and does not cause the obvious reduction of the mechanical property of the ligament during degradation.

However, the disadvantages of this application are: this application adopts several kinds of tows of different degradation properties to wind and forms, because different degradation speed leads to this application artificial ligament physical properties unstable in the human body, and this application also can't solve artificial ligament and abrade the condition that the granule dropped and cause the synovitis in the human body simultaneously.

Disclosure of Invention

1. Technical problem to be solved by the invention

The invention aims to solve the problem that synovitis is caused by abrasion and falling of particles of the existing artificial ligament in a human body and the problem that the existing artificial ligament has poor hydrophilicity and biocompatibility.

2. Technical scheme

In order to achieve the purpose, the technical scheme provided by the invention is as follows: the utility model provides an artificial ligament including implant the section with set up in implant the first and the canned paragraph two at section both ends, implant the both ends of section through pull the section with canned paragraph one is connected with canned paragraph two, implant section, canned paragraph one and canned paragraph two all including set up in the fastening layer at center and parcel set up in the degradation protective layer in the fastening layer outside.

Preferably, the implantation section, the first fixed section and the second fixed section are formed by rolling a woven mesh, the degradation protective layer is formed by weaving degradable materials, and the fastening layer is formed by weaving polyethylene glycol terephthalate materials.

Preferably, the implantation section, the first fixed section and the second fixed section are all formed by weaving a first weaving line and a second weaving line which are transversely and vertically interwoven; the braided wire I in the degradation protection layer of the implantation section is arranged along the length direction of the implantation section; the braided wire I in the degradation protection layer of the first fixed section is arranged along the length direction of the first fixed section; the braided wire I in the degradation protective layer of the second fixed section is arranged along the length direction of the second fixed section; and the first braided wire is made of polyethylene glycol terephthalate material, the second braided wire is perpendicular to the first braided wire, and the second braided wire is made of degradable material.

Preferably, the thickness of the degradation protection layer arranged on the implantation section, the first fixing section and the second fixing section is twice of that of the fastening layer.

Preferably, the middle section of the implantation section is provided with a folding section, and the folding section is woven by polyethylene terephthalate material.

Preferably, the first fixing section comprises a first fixing section and a second fixing section, the first fixing section and the second fixing section are arranged at the end part of the implanting section in parallel through the traction section, the second fixing section comprises a first fixing section and a second fixing section, and the first fixing section and the second fixing section are arranged at the end part of the implanting section far away from the first fixing section in parallel through the traction section.

Preferably, the traction segment is woven from a polyethylene terephthalate material.

3. Advantageous effects

Compared with the prior art, the technical scheme provided by the invention has the following beneficial effects:

the artificial ligament comprises an implantation section, a first fixing section and a second fixing section, wherein the first fixing section and the second fixing section are arranged at two ends of the implantation section, two ends of the implantation section are connected with the first fixing section and the second fixing section through traction sections, and the implantation section, the first fixing section and the second fixing section respectively comprise a fastening layer arranged in the center and a degradation protective layer wrapped outside the fastening layer. The degradable protective layer has the advantages of good hydrophilicity and biocompatibility, and the fastening layer wrapping the center of the degradable protective layer can effectively avoid the situation that the fastening layer is abraded in a human body and particles fall off to cause synovitis.

Drawings

FIG. 1 is a schematic view of the artificial ligament of the present invention in a deployed configuration;

FIG. 2 is a schematic view of the structure of the present inventors when rolling the ligament;

FIG. 3 is a schematic structural view of the present invention after implantation in a human body;

fig. 4 is a schematic structural view of the first fixing section and the second fixing section of the present invention engaged with a sheath.

The reference numerals in the schematic drawings illustrate:

100. an implantation section; 110. a folding section; 200. a first fixed section; 210. a first fixed section I; 220. a first second fixing section; 300. a second fixed section; 310. a second first fixing section; 320. a second fixed section II; 400. a traction section; 510. a fastening layer; 520. and degrading the protective layer.

Detailed Description

In order to facilitate an understanding of the invention, the invention will now be described more fully hereinafter with reference to the accompanying drawings, in which several embodiments of the invention are shown, but which may be embodied in many different forms and are not limited to the embodiments described herein, but rather are provided for the purpose of providing a more thorough disclosure of the invention.

It will be understood that when an element is referred to as being "secured to" another element, it can be directly on the other element or intervening elements may also be present; when an element is referred to as being "connected" to another element, it can be directly connected to the other element or intervening elements may also be present; the terms "vertical," "horizontal," "left," "right," and the like as used herein are for illustrative purposes only.

Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs; the terminology used herein in the description of the invention is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention; as used herein, the term "and/or" includes any and all combinations of one or more of the associated listed items.

Example 1

Referring to fig. 1 to 4, the present embodiment provides a technical solution: the utility model provides an artificial ligament is including implanting section 100 and set up in implant the first 200 of fixed segment and the second 300 of fixed segment at section 100 both ends, the both ends of implanting section 100 through pull the section 400 with the first 200 of fixed segment and the second 300 of fixed segment are connected, implant section 100, first 200 of fixed segment and the second 300 of fixed segment and all set up in the degradation protective layer 520 in the fastening layer 510 outside including setting up in the fastening layer 510 at center and parcel, fastening layer 510 adopts the material that mechanical properties is good to make, has ensured that artificial ligament has good mechanical properties for can not lead to the secondary ligament fracture because of the motion after artificial ligament is implanted. The degradable protective layer 520 is made of degradable materials, has good hydrophilicity and biocompatibility, and can enable biological tissues in a human body to be well combined with the artificial ligament after the artificial ligament is implanted into the human body, thereby being beneficial to the recovery of the human body ligament. Simultaneously degradation protective layer 520 parcel sets up in the fastening layer 510 outside to keep apart fastening layer 510 and human tissue, make fastening layer 510 is difficult for taking place the condition that the granule dropped in wearing and tearing under the state of human motion, prevents to cause the synovitis, helps the recovery of human ligament.

In a preferred embodiment, the implantation section 100, the first fixing section 200 and the second fixing section 300 are formed by rolling a mesh grid, the degradation protection layer 520 is formed by weaving degradable materials, and the fastening layer 510 is formed by weaving polyethylene terephthalate.

In a preferable scheme, the implantation section 100, the first fixed section 200 and the second fixed section 300 are all formed by weaving a first weaving line and a second weaving line which are transversely and vertically interwoven; the braided wire I in the degradable protective layer 520 of the implantation section 100 is arranged along the length direction of the implantation section 100; the braided wire I in the degradation protection layer 520 of the first fixing segment 200 is arranged along the length direction of the first fixing segment 200; the first braided wire in the second fixed segment 300 degradation protection layer 520 is arranged along the length direction of the second fixed segment 300; and the braided wire I is made of polyethylene terephthalate material, so that the degradation protection layer 520 has better mechanical property in different length directions along the implantation section 100, the first fixing section 200 and the second fixing section 300.

The second braided wire is perpendicular to the first braided wire and made of degradable materials, so that the degradation protective layer 520 has good hydrophilicity and biocompatibility, can be better combined with biological tissues of a human body, ensures that the artificial ligament is better implanted into the human body, and enables the ligament of the human body to be better recovered.

Meanwhile, the polyethylene glycol terephthalate material and the degradable material are woven together to form the degradation protective layer 520, so that the degradation protective layer 520 is degraded more uniformly, the artificial ligament still can keep uniform mechanical property when the degradation protective layer 520 is degraded by different degrees, and a weak part of the mechanical property is not easy to generate, so that the safety and the reliability of the artificial ligament are higher, and the rapid recovery of the human ligament is facilitated. The braided wire of the fastening layer 510 is made of a polyethylene terephthalate material.

In a preferred embodiment, the degradation protection layer 520 provided on the implant segment 100, the first fixation segment 200 and the second fixation segment 300 has a thickness twice that of the fastening layer 510. At this time, the mechanical properties and degradation rates of the implant section 100, the first fixed section 200 and the second fixed section 300 are optimally matched, so that the implant section 100, the first fixed section 200 and the second fixed section 300 can maintain high mechanical properties before the degradation protective layer 520 is degraded; meanwhile, after the ligament of the human body is recovered, the degradation protection layer 520 can be completely degraded, so that the artificial ligament can be better combined with the human body, and the optimal treatment effect can be achieved.

In a preferred embodiment, a folding section 110 is disposed at a middle section of the implantation section 100, and the folding section 110 is woven from a polyethylene terephthalate material, and the folding section 110 is used for folding the implantation section 100, so as to facilitate the implantation section 100 to be implanted into a human body bone after being folded.

In a preferred embodiment, the first fixing segment 200 includes a first fixing segment 210 and a second fixing segment 220, the first fixing segment 210 and the second fixing segment 220 are disposed at the end of the implantation segment 100 in parallel through a traction segment 400, the second fixing segment 300 includes a second fixing segment 310 and a second fixing segment 320, and the first fixing segment 310 and the second fixing segment 320 are disposed at the end of the implantation segment 100 away from the first fixing segment 200 in parallel through the traction segment 400. Through being provided with the first fixed segment 200 of multistage and the second fixed segment 300 for first fixed segment 200 and second fixed segment 300 when using with the cooperation of degradable area sheath interface screw, the breach of sheath is corresponding with the first fixed segment 200 and the second fixed segment 300 of multistage in implantation process, thereby after the screw is screwed in the sheath, the surface of screw and the even contact block of first fixed segment 200 and second fixed segment 300 of multistage make the screw can be to the fixed condition of first fixed segment 200 and second fixed segment 300 more stable and even.

In a preferred embodiment, the pulling section 400 is woven from a polyethylene terephthalate material.

The above-mentioned embodiments only express a certain implementation mode of the present invention, and the description thereof is specific and detailed, but not construed as limiting the scope of the present invention; it should be noted that, for those skilled in the art, without departing from the concept of the present invention, several variations and modifications can be made, which are within the protection scope of the present invention; therefore, the protection scope of the present patent shall be subject to the appended claims.

Claims

1. An artificial ligament, comprising: including implant section (100) and set up in the fixed segment one (200) and the fixed segment two (300) of implanting section (100) both ends, the both ends of implanting section (100) through pull section (400) with fixed segment one (200) and fixed segment two (300) are connected, implant section (100), fixed segment one (200) and fixed segment two (300) all including setting up in central fastening layer (510) and parcel set up in the degradation protective layer (520) in the fastening layer (510) outside.

2. An artificial ligament according to claim 1, wherein: implant section (100), fixed segment one (200) and fixed segment two (300) and roll up by the mesh grid and make and form, just degradation protective layer (520) are woven by degradable material and are formed, fastening layer (510) are woven by the material of polyethylene terephthalate and are formed.

3. An artificial ligament according to claim 2, wherein: the implantation section (100), the first fixed section (200) and the second fixed section (300) are all formed by weaving a first weaving line and a second weaving line which are transversely and vertically interwoven; the braided wire I in the degradation protection layer (520) of the implantation section (100) is arranged along the length direction of the implantation section (100); the braided wire I in the degradation protection layer (520) of the first fixed section (200) is arranged along the length direction of the first fixed section (200); the first braided wire in the degradation protective layer (520) of the second fixed section (300) is arranged along the length direction of the second fixed section (300); and the first braided wire is made of polyethylene glycol terephthalate material, the second braided wire is perpendicular to the first braided wire, and the second braided wire is made of degradable material.

4. An artificial ligament according to any one of claims 1-3, wherein: the thickness of the degradation protection layer (520) arranged on the implantation section (100), the first fixing section (200) and the second fixing section (300) is twice that of the fastening layer (510).

5. An artificial ligament according to claim 1, wherein: the middle section of the implantation section (100) is provided with a folding section (110), and the folding section (110) is woven by polyethylene terephthalate material.

6. An artificial ligament according to claim 1, wherein: the first fixing section (200) comprises a first fixing section (210) and a second fixing section (220), the first fixing section (210) and the second fixing section (220) are arranged at the end part of the implantation section (100) in parallel through a traction section (400), the second fixing section (300) comprises a second fixing section (310) and a second fixing section (320), and the second fixing section (310) and the second fixing section (320) are arranged at the end part of the implantation section (100) far away from the first fixing section (200) in parallel through the traction section (400).

7. An artificial ligament according to claim 1 or 6, wherein: the traction section (400) is woven from a polyethylene terephthalate material.