CN112515637A - Electrocardiosignal noise reduction method based on group sparsity characteristic - Google Patents

Electrocardiosignal noise reduction method based on group sparsity characteristic Download PDF

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CN112515637A
CN112515637A CN202011397754.7A CN202011397754A CN112515637A CN 112515637 A CN112515637 A CN 112515637A CN 202011397754 A CN202011397754 A CN 202011397754A CN 112515637 A CN112515637 A CN 112515637A
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optimal solution
electrocardiosignal
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noise reduction
group sparsity
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陈长芳
舒明雷
刘瑞霞
杨媛媛
魏诺
孔祥龙
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Shandong Institute of Artificial Intelligence
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7203Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal

Abstract

A group sparsity characteristic-based electrocardiosignal noise reduction method fully utilizes the group sparsity characteristic of electrocardiosignals and promotes the group sparsity of understanding by reasonably selecting a signal group sparsity measurement function. Based on the characteristics of a banded system, only one tri-diagonal equation set needs to be solved for each iteration, the effectiveness and the calculation efficiency of the algorithm are improved, the method is suitable for non-overlapped group sparse signals, and when the group sparse signals are overlapped, the method is still effective. By selecting the strictly convex cost function, the convergence of the algorithm is ensured, the only optimal solution is finally converged, and the accurate and efficient noise reduction is achieved while the waveform characteristics of the original electrocardiosignal are maintained.

Description

Electrocardiosignal noise reduction method based on group sparsity characteristic
Technical Field
The invention relates to the technical field of electrocardiosignal noise reduction, in particular to an electrocardiosignal noise reduction method based on group sparsity.
Background
The aging problem of population and unhealthy life style of people lead to the rapid increase of the number of residents suffering from cardiovascular diseases in China in recent years. Nowadays, cardiovascular diseases are the first killers threatening human life and health, and have the characteristics of high morbidity, disability rate and fatality rate, and low treatment rate and control rate. Electrocardiogram (ECG), which is a bioelectrical signal for recording the electrical activity of the heart, has been widely used for diagnosis of cardiovascular diseases because of its simplicity and non-invasiveness. However, the electrocardiographic signal is an extremely weak electrophysiological signal, and is very susceptible to various external noises and interferences during the acquisition process. Such as power line interference, baseline drift, muscle noise, electrode motion artifacts, etc., which will cause waveform distortion of the original electrocardiographic signal, and have an important impact on the subsequent analysis of the electrocardiographic signal, even cause a doctor to make an erroneous evaluation on the patient, therefore, the noise reduction processing of the electrocardiographic signal is very important for the clinical diagnosis and classification of cardiovascular diseases.
The electrocardiosignal and the differential signal thereof have the group sparsity characteristic, namely, the electrocardiosignal not only has the sparsity characteristic, but also has the clustering or grouping characteristic. In particular, the large values of the cardiac signal itself and its derivative are not isolated, but generally occur near or adjacent to other large values. At present, the denoising method for electrocardiosignals comprises adaptive filtering, principal component analysis, empirical mode decomposition, neural network, wavelet transformation, sparse denoising and the like. The traditional filtering method has the phenomenon that the detail information of the signal and noise are discarded together, and the self sparse characteristic of the electrocardiosignal cannot be well utilized. The sparse noise reduction method based on the L1 norm can guarantee the sparsity of the solution, but the peak value of the electrocardiosignal is easily under-estimated, and the original signal information is lost. The full-variation noise reduction method improves the problem of signal peak value underestimation, retains more signal detail characteristics, and is easy to generate sawtooth waveforms, so that the signal waveforms are not smooth enough. Therefore, how to better utilize the group sparsity of the electrocardiosignal itself is a challenging problem in the academic and medical fields while maintaining the waveform characteristics of the original electrocardiosignal and achieving accurate and efficient noise reduction effects.
Disclosure of Invention
In order to overcome the defects of the technology, the invention provides the electrocardiosignal noise reduction method based on the group sparsity characteristic, and the electrocardiosignal is more accurately and efficiently estimated by selecting the strictly convex cost function and utilizing the characteristic of a banded system.
The technical scheme adopted by the invention for overcoming the technical problems is as follows:
an electrocardiosignal noise reduction method based on group sparsity characteristics comprises the following steps:
a) establishing an electrocardiosignal mathematical model such as y ═ x + w, wherein y ∈ RNIs a noisy electrocardiosignal, x is a clean electrocardiosignal, x ═ x (0), x (1), x (n)]T∈RN,w∈RNFor added noise signals, RNReal number space of N dimensions, xn,K=[x(n),...,x(n+K-1)]T∈RK,0≤n≤N-K,xn,KRepresenting a vector with a starting index n and consisting of K points in the vector x;
b) building a convex optimization problem for a variable x by solving an optimal solution x of the convex optimization problem*Obtaining a clean electrocardiosignal x, namely x*=x;
c) Based on an alternating direction multiplier method, enabling x to be equal to z, and enabling z to be an auxiliary variable, and obtaining a convex optimization problem about the variables x and z;
d) calculating an optimal solution through an iterative algorithm based on an optimization minimum method;
e) judging whether the iteration result meets the set convergence condition, if not, returning to the step d) to continue the iteration until the convergence condition is met, and finally obtaining the optimal solution x of the convex optimization problem*Optimal solution x of the convex optimization problem*Is a clean electrocardiosignal.
Further, in step b), the formula is used
Figure BDA0002812821760000021
Computing an optimal solution x*In the formula
Figure BDA0002812821760000022
|xiI denotes the ith element x of xiF (x) is a convex optimization function, arg represents a variable corresponding to the minimum value of f (x), and D isFirst order differential matrix, D ∈ R(N-1)×N
Figure BDA0002812821760000023
λ1And λ2Are all constant, phi1(x) Phi and phi2(Dx) is the selected electrocardiosignal group sparsity measuring function,
Figure BDA0002812821760000031
0≤k≤K-1,s=Dx。
further, the formula is used in step c)
Figure BDA0002812821760000032
Establishing an optimization problem, wherein z*Is the optimal solution for z.
Further, step d) comprises the following steps:
d-1) by the formula
Figure BDA0002812821760000033
Iteratively solving the minimization problem to obtain the optimal solution x of the ith step(i)Where eta is a constant, eta > 0, d is an optimization variable, F1(x) Has a maximum function of G1(x,r),
Figure BDA0002812821760000034
r is an auxiliary variable, C1Is a constant that is independent of x,
Figure BDA0002812821760000035
0≤j≤K-1,[Λ(r)]n,nis the element of the N-th row and the N-th column of Λ (r), and Λ (r) is an NxNth order matrix, when x ≠ r, G1(x,r)≥F1(x) When x is r, G1(r,r)=F1(x) Wherein, in the step (A),
Figure BDA0002812821760000036
by the formula
Figure BDA0002812821760000037
Calculating to obtain the (i + 1) th stepIterative optimal solution x(i+1)
Figure BDA0002812821760000038
I is an identity matrix [ ·]-1Is the inverse of the matrix, z(i)Is the optimal solution of step Z, d(i)Is the optimal solution of the ith step, wherein
Figure BDA0002812821760000041
[Λ(x(i))]n,nIs Λ (x)(i)) The nth row and the nth column of elements,
Figure BDA0002812821760000042
d-2) by the formula
Figure BDA0002812821760000043
Iteratively solving the minimization problem to obtain the optimal solution z of the step i(i)Wherein v is Dz, vn,KIs a vector of vector v with a starting index n and consisting of K successive points, F2(z) has a maximum function of G2(z,u),
Figure BDA0002812821760000044
Figure BDA0002812821760000045
0≤j≤K-1,[Λ(Du)]n,nRow n and column n of Λ (Du), where ξ Du, T is the matrix transpose, C2Is a constant independent of z, u is an auxiliary variable, and G is a constant independent of z when z ≠ u2(z,u)≥F2(z) when z is u, G2(u,u)=F2(u) wherein,
Figure BDA0002812821760000046
by the formula
Figure BDA0002812821760000047
Calculating to obtain the i +1 st step iterative optimal solution z(i+1)
Figure BDA0002812821760000048
In the formula
Figure BDA0002812821760000049
Figure BDA0002812821760000051
0≤j≤K-1,[Λ(Dz(i))]n,nIs Λ (Dz)(i)) Of the nth row and the nth column of (1), wherein v(i)=Dz(i)
d-3) by the formula d(i+1)=d(i)-(z(i+1)-x(i+1)) Iterating to obtain the optimal solution d of the (i + 1) th step(i+1),d(i)And (4) obtaining the optimal solution of the step (i).
Further, step e) is based on the formula
Figure BDA0002812821760000052
Calculating the convergence criterion F (x)(i)) In the formula c0For given constant, when the iteration result is not satisfied, returning to the step d) by the formula
Figure BDA0002812821760000053
And d(i+1)=d(i)-(z(i+1)-x(i +1)) The iteration continues.
The invention has the beneficial effects that: the staircase artifact caused by the noise reduction of the electrocardiosignals based on the total variation method is effectively solved, so that the waveform characteristics of the original electrocardiosignals are kept, the group sparsity characteristic of the electrocardiosignals is fully utilized by reasonably selecting a signal group sparsity measurement function, and the group sparsity of the electrocardiosignals is promoted to be known. Based on the characteristics of a banded system, only one tri-diagonal equation set needs to be solved for each iteration, the effectiveness and the calculation efficiency of the algorithm are improved, the method is suitable for non-overlapped group sparse signals, and when the group sparse signals are overlapped, the method is still effective. By selecting the strictly convex cost function, the convergence of the algorithm is ensured, the only optimal solution is finally converged, and the accurate and efficient noise reduction is achieved while the waveform characteristics of the original electrocardiosignal are maintained.
Detailed Description
The present invention is further explained below.
An electrocardiosignal noise reduction method based on group sparsity characteristics comprises the following steps:
a) establishing an electrocardiosignal mathematical model such as y ═ x + w, wherein y ∈ RNIs a noisy electrocardiosignal, x is a clean electrocardiosignal, x ═ x (0), x (1), x (n)]T∈RN,w∈RNFor added noise signals, RNReal number space of N dimensions, xn,K=[x(n),...,x(n+K-1)]T∈RK,0≤n≤N-K,xn,KRepresents that the initial subscript in the vector x is N and the vector consisting of K points is not less than 0 and not more than N and not more than N-K;
b) due to the electrocardiosignal x and the differentiation thereof
Figure BDA0002812821760000063
All are group sparse, in order to promote the group sparsity of the solution, an electrocardiosignal group sparsity measurement function is selected, a convex optimization problem about a variable x is established, and the optimal solution x of the convex optimization problem is solved*Obtaining a clean electrocardiosignal x, namely x*=x;
c) Based on an alternating direction multiplier method, enabling x to be equal to z, and enabling z to be an auxiliary variable, and obtaining a convex optimization problem about the variables x and z;
d) calculating an optimal solution through an iterative algorithm based on an optimization minimum method;
e) judging whether the iteration result meets the set convergence condition, if not, returning to the step d) to continue the iteration until the convergence condition is met, and finally obtaining the optimal solution x of the convex optimization problem*Optimal solution x of the convex optimization problem*The electrocardiosignal is clean, thereby realizing the aim of noise reduction of the electrocardiosignal.
By the method, stair artifacts caused by noise reduction of the electrocardiosignals based on a total variation method are effectively solved, so that the waveform characteristics of the original electrocardiosignals are kept, the group sparsity characteristic of the electrocardiosignals is fully utilized by reasonably selecting a signal group sparsity measurement function, and the group sparsity of understanding is promoted. Based on the characteristics of a banded system, only one tri-diagonal equation set needs to be solved for each iteration, the effectiveness and the calculation efficiency of the algorithm are improved, the method is suitable for non-overlapped group sparse signals, and when the group sparse signals are overlapped, the method is still effective. By selecting the strictly convex cost function, the convergence of the algorithm is ensured, the only optimal solution is finally converged, and the accurate and efficient noise reduction is achieved while the waveform characteristics of the original electrocardiosignal are maintained.
The purpose of electrocardiosignal noise reduction is to recover clean electrocardiosignal x from electrocardiosignal y containing noise, and the electrocardiosignal noise reduction is realized by an optimization method because of the electrocardiosignal x and the differential thereof
Figure BDA0002812821760000064
Are all group sparse, and further, in step b), the group sparsity of the solution is promoted by a formula
Figure BDA0002812821760000061
Computing an optimal solution x*In the formula
Figure BDA0002812821760000062
|xiI denotes the ith element x of xiF (x) is a convex optimization function, arg denotes the variable corresponding to the minimum of f (x), D is a first order differential matrix,
Figure BDA0002812821760000071
λ1and λ2Are all constant, phi1(x) Phi and phi2(Dx) is the selected electrocardiosignal group sparsity measuring function,
Figure BDA0002812821760000072
0≤k≤K-1,s=Dx。
further, the formula is used in step c)
Figure BDA0002812821760000073
Establishing an optimization problem, wherein z*Is the optimal solution for z.
Further, step d) comprises the following steps:
d-1) by the formula
Figure BDA0002812821760000074
Iteratively solving the minimization problem to obtain the optimal solution x of the ith step(i)Where eta is a constant, eta > 0, d is an optimization variable, F1(x) Has a maximum function of G1(x,r),
Figure BDA0002812821760000075
r is an auxiliary variable, C1Is a constant that is independent of x,
Figure BDA0002812821760000076
0≤j≤K-1,[Λ(r)]n,nis the element of the N-th row and the N-th column of Λ (r), and Λ (r) is an NxNth order matrix, when x ≠ r, G1(x,r)≥F1(x) When x is r, G1(r,r)=F1(x) Wherein, in the step (A),
Figure BDA0002812821760000077
by the formula
Figure BDA0002812821760000089
The (i + 1) th step iteration optimal solution x is obtained through calculation(i+1)
Figure BDA0002812821760000081
I is an identity matrix [ ·]-1Is the inverse of the matrix, z(i)Is the optimal solution of step Z, d(i)Is the optimal solution of the ith step, wherein
Figure BDA0002812821760000082
[Λ(x(i))]n,nIs Λ (x)(i)) The nth row and the nth column of elements,
Figure BDA0002812821760000083
d-2) by the formula
Figure BDA0002812821760000084
Iteratively solving the minimization problem to obtain the optimal solution z of the step i(i)Wherein v is Dz, vn,KIs a vector of vector v with a starting index n and consisting of K successive points, F2(z) has a maximum function of G2(z,u),
Figure BDA0002812821760000085
Figure BDA0002812821760000086
0≤j≤K-1,[Λ(Du)]n,nRow n and column n of Λ (Du), where ξ Du, T is the matrix transpose, C2Is a constant independent of z, u is an auxiliary variable, and G is a constant independent of z when z ≠ u2(z,u)≥F2(z) when z is u, G2(u,u)=F2(u) wherein,
Figure BDA0002812821760000087
by the formula
Figure BDA0002812821760000088
Calculating to obtain the i +1 st step iterative optimal solution z(i+1)
Figure BDA0002812821760000091
In the formula
Figure BDA0002812821760000092
Figure BDA0002812821760000093
0≤j≤K-1,[Λ(Dz(i))]n,nIs Λ (Dz)(i)) Of the nth row and the nth column of (1), wherein v(i)=Dz(i)
d-3) by the formula d(i+1)=d(i)-(z(i+1)-x(i+1)) Iterating to obtain the optimal solution d of the (i + 1) th step(i+1),d(i)And (4) obtaining the optimal solution of the step (i).
Further, step e) is based on the formula
Figure BDA0002812821760000094
Calculating the convergence criterion F (x)(i)) In the formula c0For given constant, when the iteration result is not satisfied, returning to the step d) by the formula
Figure BDA0002812821760000095
And d(i+1)=d(i)-(z(i+1)-x(i +1)) The iteration continues.

Claims (5)

1. An electrocardiosignal noise reduction method based on group sparsity characteristics is characterized by comprising the following steps:
a) establishing an electrocardiosignal mathematical model such as y ═ x + w, wherein y ∈ RNIs a noisy electrocardiosignal, x is a clean electrocardiosignal, x ═ x (0), x (1), x (n)]T∈RN,w∈RNFor added noise signals, RNReal number space of N dimensions, xn,K=[x(n),...,x(n+K-1)]T∈RK,0≤n≤N-K,xn,KRepresenting a vector with a starting index n and consisting of K points in the vector x;
b) building a convex optimization problem for a variable x by solving an optimal solution x of the convex optimization problem*Obtaining a clean electrocardiosignal x, namely x*=x;
c) Based on an alternating direction multiplier method, enabling x to be equal to z, and enabling z to be an auxiliary variable, and obtaining a convex optimization problem about the variables x and z;
d) calculating an optimal solution through an iterative algorithm based on an optimization minimum method;
e) judging whether the iteration result meets the set convergence condition, if not, returning to the step d) to continue the iteration until the convergence condition is met, and finally obtaining the optimal solution x of the convex optimization problem*Optimal solution x of the convex optimization problem*Is a clean electrocardiosignal.
2. The electrocardiosignal noise reduction method based on the group sparsity characteristic as claimed in claim 1, wherein:
in step b) by the formula
Figure FDA0002812821750000011
Computing an optimal solution x*In the formula
Figure FDA0002812821750000012
|xiI denotes the ith element x of xiIs given by f (x), arg denotes the variable corresponding to the minimum of f (x), D is a first order differential matrix, D ∈ R(N-1)×N
Figure FDA0002812821750000013
λ1And λ2Are all constant, phi1(x) Phi and phi2(Dx) is the selected electrocardiosignal group sparsity measuring function,
Figure FDA0002812821750000021
Figure FDA0002812821750000022
0≤k≤K-1,s=Dx。
3. the electrocardiosignal noise reduction method based on the group sparsity characteristic as claimed in claim 3, wherein: in step c) using the formula x*,
Figure FDA0002812821750000023
Establishing an optimization problem, wherein z*Is the optimal solution for z.
4. The electrocardiosignal noise reduction method based on the group sparsity characteristic as claimed in claim 4, wherein the step d) comprises the following steps:
d-1) by the formula
Figure FDA0002812821750000024
Iteratively solving the minimization problem to obtain the optimal solution x of the ith step(i)Where eta is a constant, eta > 0, and d is an optimization variable,F1(x) Has a maximum function of G1(x,r),
Figure FDA0002812821750000025
r is an auxiliary variable, C1Is a constant that is independent of x,
Figure FDA0002812821750000026
0≤j≤K-1,[Λ(r)]n,nis the element of the N-th row and the N-th column of Λ (r), and Λ (r) is an NxNth order matrix, when x ≠ r, G1(x,r)≥F1(x) When x is r, G1(r,r)=F1(x) Wherein, in the step (A),
Figure FDA0002812821750000027
by the formula
Figure FDA0002812821750000028
The (i + 1) th step iteration optimal solution x is obtained through calculation(i+1)
Figure FDA0002812821750000031
I is an identity matrix [ ·]-1Is the inverse of the matrix, z(i)Is the optimal solution of step Z, d(i)Is the optimal solution of the ith step, wherein
Figure FDA0002812821750000032
[Λ(x(i))]n,nIs Λ (x)(i)) The nth row and the nth column of elements,
Figure FDA0002812821750000033
d-2) by the formula
Figure FDA0002812821750000034
Iteratively solving the minimization problem to obtain the optimal solution z of the step i(i)Wherein v is Dz, vn,KIs a vector of vector v with a starting index n and consisting of K successive points, F2(z) has a maximum function of G2(z,u),
Figure FDA0002812821750000035
Figure FDA0002812821750000036
0≤j≤K-1,[Λ(Du)]n,nRow n and column n of Λ (Du), where ξ Du, T is the matrix transpose, C2Is a constant independent of z, u is an auxiliary variable, and G is a constant independent of z when z ≠ u2(z,u)≥F2(z) when z is u, G2(u,u)=F2(u) wherein,
Figure FDA0002812821750000037
by the formula
Figure FDA0002812821750000038
Calculating to obtain the i +1 st step iterative optimal solution z(i+1)
Figure FDA0002812821750000039
In the formula
Figure FDA0002812821750000041
Figure FDA0002812821750000042
0≤j≤K-1,[Λ(Dz(i))]n,nIs Λ (Dz)(i)) Of the nth row and the nth column of (1), wherein v(i)=Dz(i)
d-3) by the formula d(i+1)=d(i)-(z(i+1)-x(i+1)) Iterating to obtain the optimal solution d of the (i + 1) th step(i+1),d(i)And (4) obtaining the optimal solution of the step (i).
5. The electrocardiosignal noise reduction method based on the group sparsity characteristic as claimed in claim 5, wherein: in step e) by formula
Figure FDA0002812821750000043
Calculating the convergence criterion F (x)(i)) In the formula c0For given constant, when the iteration result is not satisfied, returning to the step d) by the formula
Figure FDA0002812821750000044
And d(i+1)=d(i)-(z(i+1)-x(i +1)) The iteration continues.
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