CN112469341A - Ultrasonic image processing method and equipment and storage medium - Google Patents
Ultrasonic image processing method and equipment and storage medium Download PDFInfo
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- CN112469341A CN112469341A CN201880095965.XA CN201880095965A CN112469341A CN 112469341 A CN112469341 A CN 112469341A CN 201880095965 A CN201880095965 A CN 201880095965A CN 112469341 A CN112469341 A CN 112469341A
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Abstract
The embodiment of the invention discloses an ultrasonic image processing method, equipment and a storage medium, wherein the method comprises the following steps: determining a region of interest in an ultrasound image of an examination object; determining an original ultrasonic echo signal corresponding to the region of interest; determining a preset reference echo signal corresponding to the region of interest, wherein the preset reference echo signal is an original reference ultrasonic echo signal of a reference region of the inspection object, which is different from the region of interest; and determining the evaluation parameters of the region of interest according to the original ultrasonic echo signal and a preset reference echo signal.
Description
The embodiment of the invention relates to an image processing technology in the field of medical instruments, in particular to an ultrasonic image processing method and equipment and a storage medium.
With the improvement of medical level and medical equipment research and development technology, the medical equipment is adopted to carry out health index examination or evaluation, and plays a very important role in discovery and treatment of diseases. For example, with the advancement of obstetrical and neonatal intensive care techniques, the survival rate of premature infants, especially very low birth weight infants, has increased dramatically, as has the incidence of premature brain injury. In the case of very low birth weight live infants, neurological diseases such as cerebral palsy, cognitive, behavioral deficits or mild dyskinesia are very likely to occur, and the incidence of the diseases is mainly caused by White Matter Injury (WMI) of premature infants, especially softening of Periventricular White Matter (PVL). Therefore, it is important to provide an index for detecting and evaluating diseases such as brain injury.
Currently, due to the advantages of convenience, bedside dynamic viewing, relative cheapness and no radiation damage, in many application scenarios, ultrasonic detection of a target region of an examination object (i.e. the region to be examined) has been listed as the preferred examination method, for example, neonatal skull ultrasound examination. In the early stage of white matter injury of brain, ultrasound is mainly manifested as symmetrical echo enhancement due to edema, so that the white matter injury of brain can be quantitatively analyzed by measuring the intensity of echo. Clinical studies indicate that an increase in the intensity of the echo is positively correlated with the extent of white matter damage, which is helpful in prognosis judgment and clinical early treatment guidance.
However, quantitative analysis in clinical practice is usually evaluated by the gray values of ultrasound images obtained by ultrasound. The gray value based on the ultrasound image is affected by a plurality of parameters (transmitting, receiving and post-processing), and has great difference between different ultrasound probes and different ultrasound examination modes, thereby causing the accuracy of index examination to be reduced.
Disclosure of Invention
The embodiment of the invention provides an ultrasonic image processing method and equipment and a storage medium, which can improve the accuracy and stability of evaluation.
The embodiment of the invention provides an ultrasonic image processing method, which comprises the following steps:
determining a region of interest in an ultrasound image of an examination object;
determining an original ultrasonic echo signal corresponding to the region of interest;
determining a preset reference echo signal corresponding to the region of interest, wherein the preset reference echo signal is an original reference ultrasonic echo signal of a reference region of the examination object, which is different from the region of interest;
and determining the evaluation parameters of the region of interest according to the original ultrasonic echo signal and the preset reference echo signal.
In the above solution, before the determining the region of interest in the ultrasound image of the examination object, the method further comprises: acquiring an ultrasonic echo signal corresponding to the inspection object;
determining an ultrasonic image of the inspection object according to the ultrasonic echo signal;
the determining of the original ultrasonic echo signal corresponding to the region of interest includes:
determining imaging position information of the region of interest in the ultrasonic image;
performing geometric transformation on the imaging position information, and determining acquisition position information of the region of interest corresponding to the inspection object;
and determining the original ultrasonic echo signal corresponding to the region of interest from the ultrasonic echo signals according to the acquisition position information.
In the above solution, the determining the region of interest in the ultrasound image includes:
determining the region of interest in the ultrasound image by an image recognition algorithm;
or receiving a gesture operation instruction for the ultrasonic image, and determining the region of interest in the ultrasonic image according to the gesture operation instruction.
In the above scheme, the determining the evaluation parameter of the region of interest according to the original ultrasonic echo signal and the preset reference echo signal includes:
acquiring first echo intensity information of the original ultrasonic echo signal and acquiring second echo intensity information of the preset reference echo signal;
determining an echo intensity difference value according to the first echo intensity information and the second echo intensity information;
and determining the evaluation parameters of the region of interest according to a preset evaluation model and the echo intensity difference value.
In the foregoing scheme, the obtaining second echo strength information of the preset reference echo signal includes:
determining the reference region in the ultrasound image;
determining the original reference ultrasonic echo signal corresponding to the reference area from the ultrasonic echo signals, wherein the original reference ultrasonic echo signal is the preset reference echo signal;
and acquiring reference echo intensity information of the original reference ultrasonic echo signal, wherein the reference echo intensity information is the second echo intensity information.
In the above scheme, the acquiring first echo intensity information of the original ultrasonic echo signal includes:
counting the internal gain of the second machine in different ultrasonic modes;
and determining the first echo intensity information according to the original ultrasonic echo signal and the internal gain of the second machine.
In the foregoing scheme, the obtaining second echo strength information of the preset reference echo signal includes:
counting the preset reference echo signals corresponding to the reference areas of different collection batches;
counting the internal gains of the first machine in different ultrasonic modes;
and determining the second echo strength information according to the preset reference echo signal and the internal gain of the first machine.
The embodiment of the invention also provides an ultrasonic image processing method, which comprises the following steps:
transmitting ultrasonic waves to an inspection object;
receiving an ultrasonic echo signal based on the ultrasonic wave returned from the inspection object;
determining an ultrasonic image of the inspection object according to the ultrasonic echo signal;
determining a region of interest in the ultrasound image;
determining an original ultrasonic echo signal corresponding to the region of interest;
determining a preset reference echo signal corresponding to the region of interest, wherein the preset reference echo signal is an original reference ultrasonic echo signal of a reference region of the examination object, which is different from the region of interest;
and determining the evaluation parameters of the region of interest according to the original ultrasonic echo signal and the preset reference echo signal.
An embodiment of the present invention further provides an ultrasound image processing apparatus, including: a processor, a memory, the memory communicatively coupled with the processor;
the memory is used for storing the executable instructions of the processor or running a related program for processing the ultrasonic image;
the processor is used for calling the related program of the ultrasonic image processing stored in the memory and executing the determination of the region of interest in the ultrasonic image of the inspection object; determining an original ultrasonic echo signal corresponding to the region of interest; determining a preset reference echo signal corresponding to the region of interest, wherein the preset reference echo signal is an original reference ultrasonic echo signal of a reference region of the examination object, which is different from the region of interest; and determining the evaluation parameters of the region of interest according to the original ultrasonic echo signal and the preset reference echo signal.
In the above device, the processor is further configured to acquire an ultrasonic echo signal corresponding to an inspection object before determining a region of interest in an ultrasonic image of the inspection object; determining an ultrasonic image of the inspection object according to the ultrasonic echo signal;
the processor is further specifically configured to determine imaging position information of the region of interest in the ultrasound image; performing geometric transformation on the imaging position information, and determining acquisition position information of the region of interest corresponding to the inspection object; and determining the original ultrasonic echo signal corresponding to the region of interest from the ultrasonic echo signals according to the acquisition position information.
In the above apparatus, the processor is further specifically configured to determine the region of interest in the ultrasound image through an image recognition algorithm;
alternatively, the first and second electrodes may be,
the processor is further specifically configured to receive a gesture operation instruction for the ultrasound image, and determine the region of interest in the ultrasound image according to the gesture operation instruction.
In the above device, the processor is further specifically configured to obtain first echo intensity information of the original ultrasonic echo signal, and obtain second echo intensity information of the preset reference echo signal; determining an echo intensity difference value according to the first echo intensity information and the second echo intensity information; and determining the evaluation parameters of the region of interest according to a preset evaluation model and the echo intensity difference value.
In the above apparatus, the processor is further specifically configured to determine the reference region in the ultrasound image; determining the original reference ultrasonic echo signal corresponding to the reference area from the ultrasonic echo signals, wherein the original reference ultrasonic echo signal is the preset reference echo signal; and acquiring reference echo intensity information of the original reference ultrasonic echo signal, wherein the reference echo intensity information is the second echo intensity information.
In the above device, the processor is further specifically configured to count the preset reference echo signals corresponding to the reference regions of different acquisition batches; counting the internal gains of the first machine in different ultrasonic modes; and determining the second echo strength information according to the preset reference echo signal and the internal gain of the first machine.
In the above apparatus, the processor is further specifically configured to count internal gains of the second machine in different ultrasound modes; and determining the first echo intensity information according to the original ultrasonic echo signal and the internal gain of the second machine.
An embodiment of the present invention provides an ultrasound image processing system, including:
an ultrasonic probe;
a transmitting/receiving sequence controller which excites the ultrasonic probe to transmit ultrasonic waves to a detection object through a transmitting/receiving selection switch; and receiving an ultrasonic echo signal based on the ultrasonic wave returned from the inspection object;
a processor, which processes the ultrasonic echo signal to obtain an ultrasonic image corresponding to the inspection object;
a display that displays the ultrasound image;
wherein the processor further performs the steps of:
generating an ultrasonic image of the inspection object according to the ultrasonic echo signal; determining a region of interest in the ultrasound image; determining an original ultrasonic echo signal corresponding to the region of interest; determining a preset reference echo signal corresponding to the region of interest, wherein the preset reference echo signal is an original reference ultrasonic echo signal of a reference region of the examination object, which is different from the region of interest; and determining the evaluation parameters of the region of interest according to the original ultrasonic echo signal and the preset reference echo signal.
The embodiment of the invention provides a computer-readable storage medium, which is applied to an ultrasound image processing device or an ultrasound image processing system, and the computer-readable storage medium stores one or more ultrasound image processing related programs, and the one or more ultrasound image processing related programs can be executed by one or more processors to implement the ultrasound image processing method.
The embodiment of the invention provides an ultrasonic image processing method and equipment and a storage medium, wherein the ultrasonic image processing equipment determines an interested area in an ultrasonic image of an inspection object; determining an original ultrasonic echo signal corresponding to the region of interest; determining a preset reference echo signal corresponding to the region of interest, wherein the preset reference echo signal is an original reference ultrasonic echo signal of a reference region of the inspection object, which is different from the region of interest; and determining the evaluation parameters of the region of interest according to the original ultrasonic echo signal and the preset reference echo signal. By adopting the technical scheme, because the ultrasonic image processing equipment is based on the acquired original ultrasonic echo signals of the region of interest in the process of carrying out ultrasonic imaging on the inspection object, therefore, the lost information and the (man-made) difference caused by data transformation in the ultrasonic imaging process are reduced, and, the ultrasound image processing apparatus may make a judgment as to whether the original ultrasound echo signal has echo increase/decrease based on a preset reference echo signal of the reference region, therefore, the index evaluation of the region of interest can be realized by directly eliminating the influence of machine parameters based on the fact that the preset reference echo signal and the original ultrasonic echo signal have similar machine parameter influence, thereby reducing the limitation that the evaluation is influenced by the equipment parameters and the like, and improving the accuracy and stability of the evaluation.
Fig. 1 is a first schematic structural diagram of an ultrasound image processing apparatus according to an embodiment of the present invention;
fig. 2 is a first flowchart illustrating an ultrasound image processing method according to an embodiment of the present invention;
fig. 3 is a second flowchart illustrating an ultrasound image processing method according to an embodiment of the present invention;
FIG. 4 is a schematic diagram of an exemplary ultrasound image I provided in accordance with an embodiment of the present invention;
FIG. 5 is a schematic diagram of an exemplary ultrasound image II provided in accordance with an embodiment of the present invention;
fig. 6 is a third schematic flowchart of an ultrasound image processing method according to an embodiment of the present invention.
So that the manner in which the features and aspects of the embodiments of the present invention can be understood in detail, a more particular description of the embodiments of the invention, briefly summarized above, may be had by reference to the embodiments, some of which are illustrated in the appended drawings.
The embodiment of the invention provides a quantitative analysis device which is not influenced by machine parameters, can be standardized, can quantitatively reflect evaluation parameters and conveniently carry out evaluation parameters, and has an important effect on various clinical practices, such as early diagnosis of brain injury degree of premature infants, liver or kidney examination and the like.
Fig. 1 is a block diagram illustrating an ultrasound imaging system 10 according to an embodiment of the present invention. The ultrasound imaging system 10 may include an ultrasound probe 100, a transmit/receive selection switch 101, a transmit/receive sequence controller 102, a processor 103, and a display 104. The transmission/reception sequence controller 102 can excite the ultrasound probe 100 to transmit an ultrasonic wave to the inspection object through the transmission/reception selection switch 101, and can also control the ultrasound probe 100 to receive an ultrasonic echo returned from the inspection object, thereby obtaining an ultrasonic echo signal/data. The processor 103 processes the ultrasound echo signals/data to obtain relevant parameters of the examination object and an ultrasound image. Ultrasound images obtained by the processor 103 may be stored in the memory 105 and displayed on the display 104.
In the embodiment of the present invention, the display 104 of the ultrasonic imaging apparatus 10 may be a touch display screen, a liquid crystal display, or the like, or may be an independent display apparatus such as a liquid crystal display, a television, or the like, which is independent of the ultrasonic imaging apparatus 10, or may be a display screen on an electronic apparatus such as a mobile phone, a tablet computer, or the like.
In the embodiment of the present invention, the memory 105 of the ultrasound imaging apparatus 10 can be a flash memory card, a solid-state memory, a hard disk, or the like.
In addition, each component in the embodiment may be integrated in one processing unit, or each unit may exist alone physically, or two or more units are integrated in one unit. The integrated unit can be realized in a form of hardware or a form of a software functional module.
Based on the understanding that the technical solution of the present embodiment essentially or a part contributing to the prior art, or all or part of the technical solution may be embodied in the form of a software product stored in a storage medium, and include several instructions for causing a computer device (which may be a personal computer, a server, or a network device, etc.) or a processor (processor) to execute all or part of the steps of the method of the present embodiment. And the aforementioned storage medium includes: examples of the medium that can store the program code include a magnetic random access Memory (FRAM), a Read Only Memory (ROM), a Programmable Read Only Memory (PROM), an Erasable Programmable Read Only Memory (EPROM), an Electrically Erasable Programmable Read Only Memory (EEPROM), a Flash Memory (Flash Memory), a magnetic surface Memory, an optical Disc, and a Compact Disc Read Only Memory (CD-ROM), and the embodiments of the present invention are not limited thereto.
The embodiment of the present invention provides a computer-readable storage medium, which is applied in an ultrasound image processing device or an ultrasound image processing system, and the computer-readable storage medium stores one or more ultrasound image processing-related programs, which can be executed by one or more processors 103 to implement some or all of the steps in ultrasound image processing or any combination of the steps in ultrasound image processing in the various embodiments of the present application.
In one embodiment of the invention, the computer readable storage medium may be the memory 105, which may be a non-volatile storage medium such as a flash memory card, a solid state memory, a hard disk, or the like.
In the embodiment of the present invention, the processor 103 of the ultrasound imaging apparatus 10 may be implemented by software, hardware, firmware or a combination thereof, and may use a circuit, a single or multiple Application Specific Integrated Circuits (ASICs), a single or multiple general purpose integrated circuits, a single or multiple microprocessors, a single or multiple programmable logic devices, or a combination of the foregoing circuits or devices, or other suitable circuits or devices, so that the processor 103 may execute the corresponding steps of the ultrasound image processing methods in the foregoing embodiments.
In some embodiments of the invention, the processor 103 further performs the steps of:
generating an ultrasonic image of the inspection object according to the ultrasonic echo signal; determining a region of interest in the ultrasound image; determining an original ultrasonic echo signal corresponding to the region of interest; determining a preset reference echo signal corresponding to the region of interest, wherein the preset reference echo signal is an original reference ultrasonic echo signal of a reference region of the examination object, which is different from the region of interest; and determining the evaluation parameters of the region of interest according to the original ultrasonic echo signal and the preset reference echo signal.
In some embodiments of the present invention, the processor 103 is further configured to acquire an ultrasound echo signal corresponding to an inspection object before determining a region of interest in an ultrasound image of the inspection object; determining an ultrasonic image of the inspection object according to the ultrasonic echo signal;
the processor 103 is further specifically configured to determine imaging position information of the region of interest in the ultrasound image; performing geometric transformation on the imaging position information, and determining acquisition position information of the region of interest corresponding to the inspection object; and determining the original ultrasonic echo signal corresponding to the region of interest from the ultrasonic echo signals according to the acquisition position information.
In some embodiments of the present invention, the processor 103 is further specifically configured to determine the region of interest in the ultrasound image through an image recognition algorithm;
alternatively, the first and second electrodes may be,
the processor 103 is further specifically configured to receive a gesture operation instruction for the ultrasound image, and determine the region of interest in the ultrasound image according to the gesture operation instruction.
In some embodiments of the present invention, the processor 103 is further specifically configured to obtain first echo strength information of the original ultrasonic echo signal, and obtain second echo strength information of the preset reference echo signal; determining an echo intensity difference value according to the first echo intensity information and the second echo intensity information; and determining the evaluation parameters of the region of interest according to a preset evaluation model and the echo intensity difference value.
In some embodiments of the present invention, the processor 103 is further specifically configured to determine the reference region in the ultrasound image; determining the original reference ultrasonic echo signal corresponding to the reference area from the ultrasonic echo signals, wherein the original reference ultrasonic echo signal is the preset reference echo signal; and acquiring reference echo intensity information of the original reference ultrasonic echo signal, wherein the reference echo intensity information is the second echo intensity information.
In some embodiments of the present invention, the processor 103 is further specifically configured to count the preset reference echo signals corresponding to the reference regions of different acquisition batches; counting the internal gains of the first machine in different ultrasonic modes; and determining the second echo strength information according to the preset reference echo signal and the internal gain of the first machine.
In some embodiments of the present invention, the processor 103 is further specifically configured to count a second machine internal gain in different ultrasound modes; and determining the first echo intensity information according to the original ultrasonic echo signal and the internal gain of the second machine.
Based on the architecture of the ultrasound image processing system 10, the following embodiments of ultrasound image processing methods are proposed.
An embodiment of the present invention provides an ultrasound image processing method, as shown in fig. 2, the method may include:
s101, determining a region of interest in an ultrasonic image of an inspection object.
The ultrasonic image processing method provided by the embodiment of the invention can be suitable for the process of carrying out ultrasonic imaging on an inspection object by adopting ultrasonic waves.
It should be noted that, in the process of performing ultrasound imaging by using ultrasound waves, the ultrasound probe is used to perform beam scanning, the scanning mode may be divided into A, B, C and D modes, and the scanning mode represents a mode in which ultrasound waves are used to acquire different physical quantities.
In the embodiment of the invention, the ultrasonic image processing device is based on the acquisition of ultrasonic echo signals, so that the ultrasonic imaging processing is carried out in a B scanning mode.
In this way, during the process of performing ultrasonic imaging on the inspection object, the transmission/reception sequence controller 102 is adopted to excite the ultrasonic probe 100 to transmit ultrasonic waves to the inspection object through the transmission/reception selection switch 101, and also can control the ultrasonic probe 100 to receive ultrasonic echoes returned from the inspection object, so as to obtain ultrasonic echo signals/data, and finally, an ultrasonic imaging ultrasonic image is obtained by adopting an ultrasonic imaging technology, namely, an ultrasonic image of the inspection object is determined according to the ultrasonic echo signals. Namely, an ultrasonic echo signal corresponding to the examination object is obtained, and an ultrasonic image of the examination object is determined according to the ultrasonic echo signal.
In this embodiment of the present invention, the ultrasound image processing apparatus may be an apparatus that has an ultrasound probe and can perform ultrasound imaging, and the specific embodiment of the present invention is not limited.
It should be noted that, the process of performing ultrasonic imaging by using ultrasonic waves may use a conventional focusing imaging technology, or may use an ultrasonic plane wave technology, and the embodiment of the present invention is not limited.
In the conventional focused imaging technology, transmit beams # 1, #2, …, # N, and the like are transmitted by an ultrasonic probe, and an ultrasound image is obtained by receiving a receive beam of the transmit beam for imaging. The ultrasonic plane wave technology can carry out universe receiving only by transmitting once full-array element transmitting excitation to obtain a frame of ultrasonic image, so that the transmitting times of the ultrasonic plane wave technology is 1/N of that of the traditional single-beam focusing imaging technology, even if the traditional focusing imaging method uses a parallel multi-beam processing method of double beams, four beams, even eight beams and the like to improve the frame rate, the advantages of the plane wave in the aspect of reducing the transmitting times are still huge, and finally the imaging frame rate is greatly improved by using the ultrasonic plane wave technology.
In the embodiment of the present invention, the ultrasound image processing apparatus may employ any one of the ultrasound imaging technologies described above, and the embodiment of the present invention is not limited.
It should be noted that, in the embodiment of the present invention, since the ultrasound image processing apparatus needs to perform ultrasound imaging processing on the organ during the index evaluation, that is, the target object of ultrasound detection is the examination object.
In an embodiment of the invention, the examination object characterizes the body or a part of an organ of the body of the examined person (or animal), for example, a skull object, a liver object or a kidney object, etc.; the indexes can be correspondingly as follows: brain damage degree, fatty liver examination data or liver and kidney examination data, etc., the embodiments of the present invention are not limited.
In the embodiment of the present invention, after the processor of the ultrasound image processing device acquires an ultrasound image of ultrasound imaging, since the ultrasound image processing device needs to perform index evaluation on an area of interest, the ultrasound image processing device needs to acquire ultrasound data of the area of interest that can be determined, and then the processor of the ultrasound image processing device determines an area of interest representing a key area for performing index evaluation based on the ultrasound image, that is, determines the area of interest in the ultrasound image of the inspection object, and then processes the area of interest to perform index evaluation. Wherein the region of interest characterizes a region of index evaluation of the examination object.
For example, when the index is a brain injury, the region for characterizing the evaluation of the index may be a white matter around the ventricle, or may be another region in which the index can be detected, and the embodiment of the present invention is not limited. When the index is fatty liver examination data, the region for which the index evaluation is performed may be characterized as a liver or the like, and the embodiment of the present invention is not limited thereto.
In some embodiments of the present invention, the processor of the ultrasound image processing device is configured to display the ultrasound image directly on the display after the ultrasound image is acquired, and the ultrasound image imaging display is a grayscale image. Thus, the determination of the region of interest may be determined by the inspector through a selection operation on the display. That is, the examiner may identify the region of interest based on the ultrasound image of the entirety of the examination object displayed on the display of the ultrasound image processing apparatus and then mark the region of interest on the display, that is, the processor of the ultrasound image processing apparatus acquires the region of interest marked by the examiner. Specifically, the processor receives a gesture operation instruction for the ultrasonic image, and determines an area of interest in the ultrasonic image according to the gesture operation instruction.
In some embodiments of the present invention, the region of interest may also be self-identified by a processor of the ultrasound image processing apparatus, that is, the region of interest is determined in the ultrasound image by an image identification algorithm; the specific implementation is as the process of S1011-S1012.
And S1011, identifying a target area corresponding to the index from the ultrasonic image through an image identification algorithm.
And S1012, determining the target area as an interested area.
In the embodiment of the present invention, the processor of the ultrasound image processing apparatus may perform image recognition on the ultrasound image, and identify a target region (i.e., a region of interest) that can be subjected to index evaluation, for example, when the index is a brain injury index, the target region (i.e., the region of interest) is a white matter region around a ventricle, so as to mark or determine the region of interest to be detected by itself.
Here, when the index is a brain injury index, the processor of the ultrasound image processing device identifies a white matter region around the ventricle from the ultrasound image through an image identification algorithm or technology; a white matter region around the ventricle is determined as a region of interest.
It should be noted that, the processor of the ultrasound image processing apparatus may identify the white matter region around the ventricle by performing feature extraction on the ultrasound image and performing identification based on the extracted features.
In the embodiments of the present invention, there are many methods for extracting features, including: random forest, SIFT, Histogram of Oriented Gradient (HOG), etc., and the features extracted from the random forest can be used to express image features in the ultrasound image, and based on the image features, the processor of the ultrasound image processing device can identify the region of interest.
Further, in the embodiment of the present invention, the processor of the ultrasound image processing apparatus may further identify the region of interest such as white matter through a deep learning algorithm, such as a convolutional neural network, and the like, which is not limited in the embodiment of the present invention.
The mode of determining the region of interest by the processor of the ultrasound image processing device is not limited in the embodiments of the present invention.
In the embodiment of the present invention, the target region, i.e., the region of interest, corresponds to the index, that is, it is determined which index needs to be evaluated, and then a part or an organ corresponding to the index is evaluated as the target region, i.e., the region of interest. For example, in the embodiment of the present invention, for fatty liver assessment, the region of interest is a liver, the reference region is a kidney, and the difference between the echo intensities of the liver and the kidney is compared to perform index assessment.
Therefore, the ultrasound image processing method provided by the embodiment of the present invention is suitable for a health examination scene of different organs or different body parts, such as a brain injury examination, a fatty liver examination, or a liver-kidney contrast, and the embodiment of the present invention is not limited.
S102, determining an original ultrasonic echo signal corresponding to the region of interest;
s103, determining a preset reference echo signal corresponding to the region of interest, wherein the preset reference echo signal is an original reference ultrasonic echo signal of a reference region of the inspection object, which is different from the region of interest.
After the processor of the ultrasound image processing device determines the region of interest, the processor may determine the index by determining the echo enhancement/attenuation of the region of interest, and then the processor acquires the ultrasound echo signal corresponding to the region of interest and the preset reference echo signal corresponding to the region of interest. The preset reference echo signal is an echo signal of a reference area which can be determined in advance. The preset reference echo signal is an ultrasonic echo signal of a reference region different from the region of interest in the examination object.
In the embodiment of the present invention, the processor of the ultrasound image processing apparatus may perform subsequent index evaluation by using the original ultrasound echo information of the region of interest through the ultrasound probe, where the original ultrasound echo signal is a signal acquired before ultrasound imaging and is not a gray value obtained by ultrasound imaging processing, that is, data transformation in the ultrasound imaging process is not performed, so that data information of the original ultrasound echo signal is relatively complete, a situation that detailed data is lost due to transformation does not exist, and the index evaluation performed by using the original ultrasound echo signal is more accurate.
The original ultrasonic echo signal is the initial echo signal collected by the ultrasonic probe, and the ultrasonic image can be formed only after the coordinate transformation and the gray scale processing are carried out on the original echo signal.
It should be noted that, since data conversion is required for the acquired echo signal (ultrasonic echo signal) in the ultrasonic imaging, data may be lost. For example, the original data (i.e., echo signals) acquired by the ultrasound probe of the ultrasound image processing apparatus may be 2 to the power of 16, but the image data displayed by the ultrasound imaging is already 256.
In an embodiment of the present invention, the process of determining the original ultrasound echo signal corresponding to the region of interest by the processor of the ultrasound image processing apparatus may include: and S1031-1033. The following were used:
s1031, determining imaging position information of the region of interest in the ultrasonic image;
s1032, carrying out geometric transformation on the imaging position information, and determining acquisition position information of an interested area corresponding to an acquisition inspection object;
and S1033, according to the acquisition position information, determining an original ultrasonic echo signal corresponding to the region of interest from the ultrasonic echo signals.
In some embodiments of the present invention, during the ultrasound imaging process, the processor of the ultrasound image processing device needs to perform geometric transformation and data transformation on the acquired region and the acquired ultrasound echo signal to obtain a sector-shaped grayscale image for display on the device. Therefore, when the original ultrasound echo signals acquired from the region of interest are to be acquired, the region of interest determined on the ultrasound image needs to be converted back to the position of the acquisition region belonging to the inspection object, and the original ultrasound echo signals corresponding to the region of interest can be found from all the ultrasound echo signals of the inspection object according to the acquisition position information.
Therefore, the processor of the ultrasound image processing device determines the imaging position information of the region of interest in the ultrasound image, performs geometric transformation (which is inverse transformation of the geometric transformation in the ultrasound imaging) on the imaging position information to obtain the acquisition position information of the region of interest when the examination object is acquired, and finally determines the original ultrasound echo signal corresponding to the acquisition position information from the ultrasound echo signals.
Here, both the imaging position information and the acquisition position information may be embodied in the form of coordinates, and the embodiment of the present invention does not limit the expression form of the position information.
And S104, determining the evaluation parameters of the region of interest according to the original ultrasonic echo signal and the preset reference echo signal.
In detail, the ultrasound image processing device may first determine a reference region, obtain a preset reference echo signal of the reference region, and then perform index evaluation on the region of interest based on the original ultrasound echo signal and the preset reference echo signal.
In the embodiment of the present invention, the reference region may be a non-region of interest in the inspection object, taking the brain injury evaluation as an example, and the reference region may be a choroid plexus region, a gray matter region, and the like, which is not limited in the embodiment of the present invention.
Therefore, the processor of the ultrasonic image processing device in the embodiment of the invention can eliminate the influence of machine parameters on the original ultrasonic echo signal based on the preset reference signal to realize index evaluation.
In an embodiment of the present invention, the preset reference echo signal may be a reference signal having a similar machine parameter influence as the original ultrasonic echo signal.
In detail, as shown in fig. 3, the process of determining the evaluation parameter of the region of interest based on the original ultrasound echo signal and the preset reference echo signal by the processor of the ultrasound image processing device may include: S1041-S1043. The following were used:
s1041, acquiring first echo intensity information of an original ultrasonic echo signal, and acquiring second echo intensity information of a preset reference echo signal;
s1042, determining an echo intensity difference value according to the first echo intensity information and the second echo intensity information;
and S1043, determining an evaluation parameter of the region of interest according to the preset evaluation model and the echo intensity difference value.
In some embodiments of the present invention, a processor of the ultrasound image processing apparatus may obtain signal strengths of an original ultrasound echo signal and a preset reference echo signal to obtain first echo strength information and second echo strength information, and determine whether echo enhancement exists by determining an echo strength difference value between the first echo strength and the second echo strength, that is, input the echo strength difference value into a preset evaluation model, and output an evaluation parameter of an index of an area of interest of an inspection object because the preset evaluation model is used to represent a relationship between an evaluation parameter of the index and the echo strength difference.
For example, the preset evaluation model is a corresponding relationship between a preset echo intensity difference value and an evaluation parameter, for example, when the echo intensity difference value is 10, the corresponding evaluation parameter is 0.1%, and the specific implementation manner is not limited in the embodiment of the present invention.
Further, in this embodiment of the present invention, the way for the processor of the ultrasound image processing device to determine the echo strength difference value between the first echo strength information and the second echo strength information may be: the first echo strength information and the second echo strength information are subjected to subtraction or quotient processing, and a specific implementation manner is not limited in the embodiment of the present invention.
Note that echo enhancement/reduction is one way of determining the index.
Further, the echo intensity difference value and the evaluation parameter can be visually displayed, taking the evaluation parameter as brain injury evaluation as an example, as shown in fig. 4, the echo intensity difference value 2 (obtained by the first echo intensity information 3-the second echo intensity information 4) obtained by analyzing the region of interest 1 and the final brain injury evaluation result 5(0db), that is, the brain injury is 0, can be displayed on the ultrasound image by using a pseudo color.
Further, in the embodiment of the present invention, the number of the regions of interest and the number of the reference regions are not limited in the embodiment of the present invention, and may be multiple or one. Therefore, the evaluation of the indexes can be realized based on the relevant data of the multiple interested areas and the multiple reference areas, and the evaluation parameters are obtained, so that the processing is more comprehensive and the effect is better.
For example, as shown in fig. 5, in the ultrasound image, a brain injury assessment method provided by an embodiment of the present invention may be performed based on an area of interest 1 and an area of interest 2 to obtain two brain injury assessment results (i.e., assessment parameters), and then the two brain injury assessment results are combined to give a final brain injury determination.
It can be understood that, in the process of performing ultrasound imaging on an inspection object, the original ultrasound echo signal of the region of interest is acquired, so that information lost by data transformation and (man-made) differences caused during the ultrasound imaging processing are reduced, and whether the original ultrasound echo signal has echo increase/decrease can be determined based on the preset reference echo signal of the reference region, so that the ultrasound image processing device can be evaluated by directly eliminating the influence of machine parameters based on the preset reference echo signal having similar machine parameter influence to the original ultrasound echo signal, thereby reducing the limitation that the evaluation of indexes is influenced by device parameters and the like, and improving the accuracy and stability of the evaluation.
The following describes a process of acquiring the preset reference echo signal by the processor of the ultrasound image processing apparatus.
In the embodiment of the present invention, there may be at least two cases of the preset reference echo signal, where the first case may be based on the same machine parameter influence in the same ultrasound imaging process, and then the reference area of the non-interest area may be determined from the ultrasound image, and the original reference ultrasound echo signal of the reference area may be obtained according to the processing process, so that the obtained echo intensity difference value is data with the same machine parameter eliminated, and is more accurate. The second method is that the preset reference echo signal may be a parameter of a region of non-interest of different people acquired based on different acquisition batches and different ultrasound modes, the preset reference echo signal may be a standardized preset reference echo signal with internal gain being deducted, and after the same standardization processing is performed on the original ultrasound echo signal, the obtained echo intensity difference value is data with influences of different acquisition batches, different ultrasound modes and the like eliminated, and the evaluation performed by using the echo intensity difference value is more accurate.
For the first processing mode, a specific process of acquiring the second echo strength information of the preset reference echo signal is as follows: determining a reference region in the ultrasound image; determining an original reference ultrasonic echo signal corresponding to a reference area from the ultrasonic echo signals, wherein the original reference ultrasonic echo signal is a preset reference echo signal; and acquiring reference echo intensity information of the original reference ultrasonic echo signal, wherein the reference echo intensity information is second echo intensity information.
For the second processing manner, the specific process of acquiring the first echo strength information of the original ultrasonic echo signal and the second echo strength information of the preset reference echo signal may include:
counting the internal gain of the second machine in different ultrasonic modes; counting preset reference echo signals corresponding to reference areas of different collection batches; determining first standard echo intensity information corresponding to the original ultrasonic echo signal according to the original ultrasonic echo signal and the internal gain of the second machine, wherein the first standard echo intensity information is first echo intensity information; and determining second standard echo intensity information corresponding to the preset reference echo signal according to the preset reference echo signal and the internal gain of the first machine, wherein the second standard echo intensity information is second echo intensity information.
It should be noted that, in the embodiment of the present invention, the second machine internal gain (machine fixed parameter) refers to the current gain in different scanning regions under different acquisition environments and ultrasound modes. The first machine internal gain (machine fixed parameter) refers to the mean gain in different scanning areas under different acquisition environments and ultrasound modes, and is a uniform estimation.
In the embodiment of the present invention, the normalization process is a process of subtracting or removing the original ultrasonic echo signal and the corresponding internal gain of the machine, or a process of subtracting or removing the reference echo signal and the corresponding internal gain of the machine is preset. The processing mode is beneficial to the standardized processing and popularization of the ultrasonic image processing method on the basis of ensuring the accurate evaluation.
Further, as shown in fig. 6, after S104, the method for processing an ultrasound image according to an embodiment of the present invention may further include: and S105. The following were used:
and S105, determining a risk evaluation result according to a preset risk analysis model and evaluation parameters.
After obtaining the evaluation parameters, the processor of the ultrasound image processing device may further perform quantization processing on the evaluation parameters to obtain a risk level, i.e., a risk evaluation result.
In the embodiment of the invention, the preset danger analysis model is obtained by sample training, and the danger analysis model can quantify the grade of the evaluation parameter and the grade of the danger to achieve the purpose of evaluating the danger degree.
In the embodiment of the invention, a processor of the ultrasonic image processing equipment needs to acquire sample data first, and model training of machine learning is carried out by adopting the sample data and a neural network, so that a preset danger analysis model is obtained.
In the model training process, the sample data includes: the evaluation parameters (or echo signal difference values) of personnel under different conditions such as different ages and different diseases and the actual crisis condition information. Wherein the sample data may be statistically obtained in an actual clinic.
In the embodiment of the invention, the processor of the ultrasonic image processing equipment inputs the evaluation parameters (echo signal difference values) of the sample data into the initial training model consisting of the neural network, outputs the training result, and continuously adjusts the initial training model by comparing the training result with the actual crisis condition information until the accuracy of the output training result reaches the standard, so that the obtained adjusted outgoing training model is the preset danger analysis model. Then, the crisis or the risk degree of the new evaluation parameter can be analyzed through the preset risk analysis model.
Illustratively, the hazard coefficient is 0.9 (assuming a hazard coefficient of 0-1) when the evaluation parameter is 50%.
Further, in the embodiment of the present invention, the risk assessment result may be processed by being visually displayed in the display of the ultrasound image processing apparatus.
It can be understood that the risk assessment method in the embodiment of the invention can also carry out the quantification of the risk coefficient through the training model, so that the risk degree is intuitively reflected, and the performance is better.
It can be understood that, in the process of performing ultrasound imaging on an inspection object, the ultrasound image processing device is based on the acquired original ultrasound echo signal of the region of interest, so that information lost by data transformation and (man-made) differences caused during the ultrasound imaging processing are reduced, and the ultrasound image processing device can determine whether the original ultrasound echo signal has echo increase/decrease based on the preset reference echo signal of the reference region, so that the evaluation can be performed by directly eliminating the influence of machine parameters based on the preset reference echo signal and the original ultrasound echo signal having similar machine parameter influence, thereby reducing the limitation that the evaluation parameters are influenced by the equipment parameters, and the like, and improving the accuracy and stability of the evaluation.
As will be appreciated by one skilled in the art, embodiments of the present invention may be provided as a method, system, or computer program product. Accordingly, the present invention may take the form of a hardware embodiment, a software embodiment, or an embodiment combining software and hardware aspects. Furthermore, the present invention may take the form of a computer program product embodied on one or more computer-usable storage media (including, but not limited to, disk storage, optical storage, and the like) having computer-usable program code embodied therein.
The present invention is described with reference to flowchart illustrations and/or block diagrams of methods, apparatus (systems), and computer program products according to embodiments of the invention. It will be understood that each flow and/or block of the flow diagrams and/or block diagrams, and combinations of flows and/or blocks in the flow diagrams and/or block diagrams, can be implemented by computer program instructions. These computer program instructions may be provided to a processor of a general purpose computer, special purpose computer, embedded processor, or other programmable data processing apparatus to produce a machine, such that the instructions, which execute via the processor of the computer or other programmable data processing apparatus, create means for implementing the functions specified in the flowchart flow or flows and/or block diagram block or blocks.
These computer program instructions may also be stored in a computer-readable memory that can direct a computer or other programmable data processing apparatus to function in a particular manner, such that the instructions stored in the computer-readable memory produce an article of manufacture including instruction means which implement the function specified in the flowchart flow or flows and/or block diagram block or blocks.
These computer program instructions may also be loaded onto a computer or other programmable data processing apparatus to cause a series of operational steps to be performed on the computer or other programmable apparatus to produce a computer implemented process such that the instructions which execute on the computer or other programmable apparatus provide steps for implementing the functions specified in the flowchart flow or flows and/or block diagram block or blocks.
The above description is only a preferred embodiment of the present invention, and is not intended to limit the scope of the present invention.
In the embodiment of the present invention, in the process of performing ultrasound imaging on an inspection object, an ultrasound image processing device is based on an acquired original ultrasound echo signal of a region of interest, so that information lost by data transformation and (man-made) differences caused during ultrasound imaging processing are reduced, and the ultrasound image processing device can determine whether the original ultrasound echo signal has echo increase/decrease based on a preset reference echo signal of a reference region, so that evaluation can be performed by directly eliminating the influence of machine parameters based on the preset reference echo signal and the original ultrasound echo signal having similar machine parameter influence, thereby reducing the limitation that evaluation parameters are influenced by device parameters, and the like, and improving the accuracy and stability of the evaluation.
Claims (17)
- A method of ultrasound image processing, the method comprising:determining a region of interest in an ultrasound image of an examination object;determining an original ultrasonic echo signal corresponding to the region of interest;determining a preset reference echo signal corresponding to the region of interest, wherein the preset reference echo signal is an original reference ultrasonic echo signal of a reference region of the examination object, which is different from the region of interest;and determining the evaluation parameters of the region of interest according to the original ultrasonic echo signal and the preset reference echo signal.
- The method of claim 1, wherein prior to determining a region of interest in an ultrasound image of an examination object, the method further comprises:acquiring an ultrasonic echo signal corresponding to the inspection object;determining an ultrasonic image of the inspection object according to the ultrasonic echo signal;the determining of the original ultrasonic echo signal corresponding to the region of interest includes:determining imaging position information of the region of interest in the ultrasonic image;performing geometric transformation on the imaging position information, and determining acquisition position information of the region of interest corresponding to the inspection object;and determining the original ultrasonic echo signal corresponding to the region of interest from the ultrasonic echo signals according to the acquisition position information.
- The method of claim 1, wherein determining a region of interest in an ultrasound image of an examination object comprises:determining the region of interest in the ultrasound image by an image recognition algorithm;or receiving a gesture operation instruction for the ultrasonic image, and determining the region of interest in the ultrasonic image according to the gesture operation instruction.
- The method of claim 1, wherein said determining evaluation parameters of the region of interest from the raw ultrasound echo signal and the preset reference echo signal comprises:acquiring first echo intensity information of the original ultrasonic echo signal and acquiring second echo intensity information of the preset reference echo signal;determining an echo intensity difference value according to the first echo intensity information and the second echo intensity information;and determining the evaluation parameters of the region of interest according to a preset evaluation model and the echo intensity difference value.
- The method according to claim 4, wherein said obtaining second echo strength information of the pre-determined reference echo signal comprises:determining the reference region in the ultrasound image;determining the original reference ultrasonic echo signal corresponding to the reference area from the ultrasonic echo signals, wherein the original reference ultrasonic echo signal is the preset reference echo signal;and acquiring reference echo intensity information of the original reference ultrasonic echo signal, wherein the reference echo intensity information is the second echo intensity information.
- The method according to claim 4, wherein said obtaining second echo strength information of the pre-determined reference echo signal comprises:counting the preset reference echo signals corresponding to the reference areas of different collection batches;counting the internal gains of the first machine in different ultrasonic modes;and determining the second echo strength information according to the preset reference echo signal and the internal gain of the first machine.
- The method of claim 4, wherein the obtaining first echo intensity information of the raw ultrasound echo signal comprises:counting the internal gain of the second machine in different ultrasonic modes;and determining the first echo intensity information according to the original ultrasonic echo signal and the internal gain of the second machine.
- An ultrasound image processing method, comprising:transmitting ultrasonic waves to an inspection object;receiving an ultrasonic echo signal based on the ultrasonic wave returned from the inspection object;determining an ultrasonic image of the inspection object according to the ultrasonic echo signal;determining a region of interest in the ultrasound image;determining an original ultrasonic echo signal corresponding to the region of interest;determining a preset reference echo signal corresponding to the region of interest, wherein the preset reference echo signal is an original reference ultrasonic echo signal of a reference region of the examination object, which is different from the region of interest;and determining the evaluation parameters of the region of interest according to the original ultrasonic echo signal and the preset reference echo signal.
- An ultrasound image processing apparatus characterized by comprising: a processor, a memory, the memory communicatively coupled with the processor;the memory is used for storing the executable instructions of the processor or running a related program for processing the ultrasonic image;the processor is used for calling the related program of the ultrasonic image processing stored in the memory and executing the determination of the region of interest in the ultrasonic image of the inspection object; determining an original ultrasonic echo signal corresponding to the region of interest; determining a preset reference echo signal corresponding to the region of interest, wherein the preset reference echo signal is an original reference ultrasonic echo signal of a reference region of the examination object, which is different from the region of interest; and determining the evaluation parameters of the region of interest according to the original ultrasonic echo signal and the preset reference echo signal.
- The apparatus of claim 9,the processor is further configured to acquire an ultrasonic echo signal corresponding to an inspection object before determining a region of interest in an ultrasonic image of the inspection object; determining an ultrasonic image of the inspection object according to the ultrasonic echo signal;the processor is further specifically configured to determine imaging position information of the region of interest in the ultrasound image; performing geometric transformation on the imaging position information, and determining acquisition position information of the region of interest corresponding to the inspection object; and determining the original ultrasonic echo signal corresponding to the region of interest from the ultrasonic echo signals according to the acquisition position information.
- The apparatus of claim 9,the processor is further specifically configured to determine the region of interest in the ultrasound image through an image recognition algorithm;alternatively, the first and second electrodes may be,the processor is further specifically configured to receive a gesture operation instruction for the ultrasound image, and determine the region of interest in the ultrasound image according to the gesture operation instruction.
- The apparatus of claim 9,the processor is further specifically configured to obtain first echo intensity information of the original ultrasonic echo signal, and obtain second echo intensity information of the preset reference echo signal; determining an echo intensity difference value according to the first echo intensity information and the second echo intensity information; and determining the evaluation parameters of the region of interest according to a preset evaluation model and the echo intensity difference value.
- The apparatus of claim 12,the processor is further specifically configured to determine the reference region in the ultrasound image; determining the original reference ultrasonic echo signal corresponding to the reference area from the ultrasonic echo signals, wherein the original reference ultrasonic echo signal is the preset reference echo signal; and acquiring reference echo intensity information of the original reference ultrasonic echo signal, wherein the reference echo intensity information is the second echo intensity information.
- The apparatus of claim 12,the processor is further specifically configured to count the preset reference echo signals corresponding to the reference regions of different acquisition batches; counting the internal gains of the first machine in different ultrasonic modes; and determining the second echo strength information according to the preset reference echo signal and the internal gain of the first machine.
- The apparatus of claim 12,the processor is further specifically configured to count internal gains of the second machine in different ultrasound modes; and determining the first echo intensity information according to the original ultrasonic echo signal and the internal gain of the second machine.
- An ultrasound image processing system, comprising:an ultrasonic probe;a transmitting/receiving sequence controller which excites the ultrasonic probe to transmit ultrasonic waves to a detection object through a transmitting/receiving selection switch; and receiving an ultrasonic echo signal based on the ultrasonic wave returned from the inspection object;a processor, which processes the ultrasonic echo signal to obtain an ultrasonic image corresponding to the inspection object;a display that displays the ultrasound image;wherein the processor further performs the steps of:generating an ultrasonic image of the inspection object according to the ultrasonic echo signal; determining a region of interest in the ultrasound image; determining an original ultrasonic echo signal corresponding to the region of interest; determining a preset reference echo signal corresponding to the region of interest, wherein the preset reference echo signal is an original reference ultrasonic echo signal of a reference region of the examination object, which is different from the region of interest; and determining the evaluation parameters of the region of interest according to the original ultrasonic echo signal and the preset reference echo signal.
- A computer-readable storage medium, which is applied to an ultrasound image processing apparatus or an ultrasound image processing system, and stores one or more ultrasound image processing apparatus evaluation-related programs executable by one or more processors to implement the ultrasound image processing method according to claims 1 to 8.
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