CN112450937A - Transparent self-adhesive conductive hydrogel electrode and preparation method thereof - Google Patents
Transparent self-adhesive conductive hydrogel electrode and preparation method thereof Download PDFInfo
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- C08J2339/00—Characterised by the use of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen; Derivatives of such polymers
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Abstract
A transparent self-adhesive conductive hydrogel electrode and a preparation method thereof, the electrode comprises: the protective film layer, the conductive hydrogel layer and the back lining layer are sequentially arranged from top to bottom, the protective film layer is a polyethylene film, the conductive hydrogel layer is chemical crosslinking type hydrogel, the conductive hydrogel layer is obtained by performing acid catalysis ketal reaction on polyvinyl alcohol and polyvinylpyrrolidone under a heating condition, the hydrogel is a three-dimensional network structure formed by the polyvinyl alcohol and the polyvinylpyrrolidone, and the back lining layer is non-woven fabric. The transparent self-adhesive conductive hydrogel electrode provided by the invention has the advantages of good biocompatibility, high transparency and high adhesiveness, simple and convenient preparation process, low material cost and suitability for large-scale production.
Description
Technical Field
The invention relates to the technical fields of sensors, bioelectricity collection/stimulation and the like, in particular to a transparent self-adhesion conductive hydrogel electrode, and particularly relates to a conductive hydrogel electrode which has high transparency and self-adhesion and is adjustable in conductive performance and electrode shape.
Background
With the rapid development of medical science and technology and the increasing concern of people on health problems, the demand of precise medical treatment and individual medical treatment is higher and higher, and various medical monitoring devices, such as blood glucose meters, heart rate monitors, muscle rehabilitation trainers, electronic physiotherapy instruments and the like, begin to enter the daily lives of the public. The instrument for monitoring based on the bioelectric signals is the most widely applied instrument, the bioelectric signals mainly comprise electroencephalogram signals (EEG), electromyogram signals (ECG), Electrocardiosignals (ECG) and the like, and by collecting or stimulating the bioelectric signals, the bioelectric signals have important clinical application values for diagnosis and treatment of brain or heart diseases, nerve or muscle injuries and the like, and also have important academic values for basic research of rehabilitation medicine, research of sports science and the like. While sensors have been the focus of research and application as the most sentinel in signal acquisition and stimulation, the market for medical sensors reached $ 82.1 billion in 2015, and $ 150 billion in 2022 with a compound growth rate of 8.5% predicted. The sensor is composed of two parts, namely an electrode and a circuit, wherein the electrode part determines the monitoring threshold value, the signal stability and the application form of the sensor, the improvement of electrode materials and performance is continuously and successfully carried out in the last two decades, the problems of safety, controllability, sensitivity, convenience and the like of the electrode are more and more emphasized nowadays, and the development trend from the traditional solid electrode to the flexible electrode is gradually formed in the research and application fields.
Hydrogel electrodes are representative of a new generation of flexible electrodes. The hydrogel is a material having a three-dimensional network structure and is rich in a large amount of moisture. The hydrogel material is soft and flexible, and has excellent biocompatibility and ion transmission capability, so that the hydrogel material is widely applied to the fields of flexible sensor preparation, wound healing, tissue engineering and the like. Compared with the traditional solid electrode, the hydrogel electrode has the characteristics close to human tissues, and can be well connected with wet and soft human tissues and dry and hard electronic components. However, the existing hydrogel electrode generally cannot meet the requirements of good biocompatibility, high transparency, high adhesion and the like, the problems of irritation, deformation of the electrode in the using process, deep color of the electrode and the like of an electrode material not only affect the monitoring result, but also lead to unsatisfactory testing experience, and in order to solve the problem, a novel hydrogel electrode which has good biocompatibility, high transparency and adhesion and adjustable and controllable conductivity and shape and size is provided.
Disclosure of Invention
The invention aims to provide a transparent self-adhesion conductive hydrogel electrode and a preparation method thereof, so that the problems that the conventional hydrogel electrode cannot simultaneously meet good biocompatibility, high transparency and high adhesion are solved, the hydrogel electrode mainly comprises polyvinyl alcohol (PVA), polyvinylpyrrolidone (PVP) and polydopamine nanodots (PDA NDs), and the material has good biocompatibility; wherein, the PVA and the PVP generate ketal reaction under the condition of heating to form covalent crosslinking sites so as to form a skeleton network of the whole hydrogel, and the process does not involve toxic and harmful organic reagents, initiators and crosslinking agents; the PDA NDs are obtained by treating polydopamine with hydrogen peroxide/sodium hydroxide, and the PDA NDs and sodium ions (Na +) jointly form an internal conductive network of the hydrogel; the hydrogel electrode has the advantages of simple preparation process and low material cost, and is suitable for large-scale production.
The invention provides a transparent self-adhesive conductive hydrogel electrode, which comprises: the protective film layer, the conductive hydrogel layer and the back lining layer are sequentially arranged from top to bottom, the protective film layer is a polyethylene film, the conductive hydrogel layer is chemical crosslinking type hydrogel and is obtained by performing acid catalysis ketal reaction on polyvinyl alcohol and polyvinylpyrrolidone under a heating condition, the hydrogel is a three-dimensional network structure formed by polyvinyl alcohol and polyvinylpyrrolidone, and the back lining layer is non-woven fabric.
Further, the conductive hydrogel layer forms a conductive network by introducing PDA NDs, derivatives of polydopamine, and Na + solution.
Furthermore, the non-woven fabric is made of polypropylene and polyurethane glue.
Furthermore, the conductive hydrogel layer is a special shape prepared by pouring and cutting the hydrogel, and the conductive hydrogel layer and the backing layer are pressed together after being mechanically coated.
Further, the hydrogel has a conductivity ranging from 0.14 to 1.47S/m.
Further, the hydrogel has a light transmittance ranging from 91 to 98%.
Further, the hydrogel has an adhesive strength to human tissue in the range of 29 to 42 kPa.
The preparation method of the transparent self-adhesive conductive hydrogel electrode comprises the following specific preparation processes: (1) preparing a hydrogel; (2) preparing a hydrogel electrode;
the preparation of the hydrogel (1) comprises the following steps:
the method comprises the following steps: adding polyvinyl alcohol (PVA) into deionized water, and heating and stirring to dissolve the PVA to obtain a PVA solution;
step two: adding polyvinylpyrrolidone (PVP) into deionized water, and dissolving with ultrasonic assistance to obtain a PVP solution;
step three: adding dopamine hydrochloride into a slightly alkaline Tris-HCl buffer solution, stirring for 12 hours in an open atmosphere to obtain a PDA solution, and then mixing and heating the PDA solution with a mixed solution of hydrogen peroxide and sodium hydroxide to obtain a polydopamine nanodot (PDA NDs) solution;
step four: uniformly mixing the PVA solution obtained in the first step, the PVP solution obtained in the second step and the polydopamine nanodot (PDA NDs) solution obtained in the third step according to a certain volume ratio;
step five: and (4) adjusting the pH value of the mixed solution obtained in the fourth step to be acidic, and heating to obtain the hydrogel.
Further, the mass percentage concentration of the polyvinyl alcohol is 15-20%, and preferably 20%; the mass percentage concentration of the polyvinylpyrrolidone is 30-40%, and preferably 40%.
Further, the mixing ratio in the fourth step can be set as 1:1:0, 1:1:0.2, 1:1:0.4, 1:1:0.6 and 1:1:0.8, and the conductivity, transparency, adhesion and mechanical properties of the final hydrogel can be adjusted by changing the ratio of PDA NDs.
(2) The preparation of the hydrogel electrode comprises the following specific operation steps:
the hydrogel electrode comprises a protective film layer, a conductive hydrogel layer and a back lining layer from top to bottom. Pouring and cutting the prepared hydrogel into a specific shape to be used as a conductive hydrogel layer; mechanically coating the conductive hydrogel layer and a backing layer, and then pressing the conductive hydrogel layer and the backing layer together, wherein the backing layer is non-woven fabric, and polypropylene and polyurethane glue are preferred; and covering a protective film layer on the conductive hydrogel layer, wherein the protective film layer is a polyethylene film.
The invention provides a transparent self-adhesive conductive hydrogel electrode, which has the beneficial effects that:
1. the prepared hydrogel electrode has good biocompatibility, high transparency and self-adhesion;
2. the conductivity, transparency and adhesion performance of the prepared hydrogel electrode can be regulated and controlled simply by changing the addition of PDA NDs, and the shape and size of the hydrogel electrode can be designed according to actual requirements;
3. the main components of the prepared hydrogel electrode are linear polymers PVA and PVP, the hydrogel electrode is non-toxic and mild, the biocompatibility is good, the type used by the invention is approved by FDA and can be used for being directly contacted with a human body, in addition, the price is low, the preparation process is relatively simple and convenient, and the hydrogel electrode is suitable for large-scale production and preparation;
4. the prepared hydrogel electrode can accurately collect myoelectric signals on the surface of an arm, and is stable in signal and good in repeatability.
Drawings
FIG. 1 is a schematic structural diagram of a transparent self-adhesive conductive hydrogel electrode according to an embodiment of the present invention;
FIG. 2 is a photograph demonstrating an embodiment of the transparent self-adhering conductive hydrogel of the present invention;
FIG. 3 is a photograph of a skin sensitization test of a transparent self-adhesive conductive hydrogel electrode according to an embodiment of the present invention;
FIG. 4 is an electromyographic sensor constructed on the basis of the transparent self-adhesive conductive hydrogel electrode and a test experimental diagram thereof.
Detailed Description
In order to make the features of the present invention more comprehensible and to explain the main components of the invention and the importance of the selected conditions, the following description is given with reference to specific examples, but it should be noted that these examples are not intended to limit the present invention, and any equivalent products obtained by simple substitution by those skilled in the art are intended to be included in the scope of the claims of the present invention.
The invention provides an embodiment of a transparent self-adhesive conductive hydrogel electrode, comprising: the protective film layer, the conductive hydrogel layer and the back lining layer are sequentially arranged from top to bottom, the protective film layer is a polyethylene film, the conductive hydrogel layer is chemical crosslinking type hydrogel, the conductive hydrogel layer is obtained by performing acid catalysis ketal reaction on polyvinyl alcohol and polyvinylpyrrolidone under a heating condition, the hydrogel is a three-dimensional network structure formed by the polyvinyl alcohol and the polyvinylpyrrolidone, and the back lining layer is non-woven fabric.
Alternatively, the conductive hydrogel layer forms a conductive network by introducing PDA NDs, a derivative of polydopamine, and a Na + solution.
Optionally, the backing layer is comprised of polypropylene and polyurethane glue.
Optionally, the conductive hydrogel layer is a hydrogel, and is prepared into a specific shape by casting and cutting, and the conductive hydrogel layer and the backing layer are pressed together after mechanical coating.
Alternatively, the hydrogel has a conductivity in the range of 0.14 to 1.47S/m.
Alternatively, the hydrogel has a light transmittance in the range of 91-98%.
Alternatively, the hydrogel has an adhesive strength to human tissue in the range of 29-42 kPa.
The invention also provides an embodiment of a preparation method of the transparent self-adhesive conductive hydrogel electrode, and the preparation method of the transparent self-adhesive conductive hydrogel electrode comprises the following specific preparation processes: (1) preparing a hydrogel; (2) preparing a hydrogel electrode;
(1) the preparation of the hydrogel comprises:
the method comprises the following steps: adding polyvinyl alcohol (PVA) into deionized water, and heating and stirring to dissolve the PVA to obtain a PVA solution;
step two: adding polyvinylpyrrolidone (PVP) into deionized water, and dissolving with ultrasonic assistance to obtain a PVP solution;
step three: adding dopamine hydrochloride into a slightly alkaline Tris-HCl buffer solution, stirring for 12 hours in an open atmosphere to obtain a PDA solution, and then mixing and heating the PDA solution with a mixed solution of hydrogen peroxide and sodium hydroxide to obtain a polydopamine nanodot (PDA NDs) solution;
step four: uniformly mixing the PVA solution obtained in the step one, the PVP solution obtained in the step two and the polydopamine nanodot (PDA NDs) solution obtained in the step three according to a certain volume ratio;
step five: and (4) adjusting the pH value of the mixed solution obtained in the fourth step to be acidic, and heating to obtain the hydrogel.
Optionally, the mass percentage concentration of the polyvinyl alcohol is 15-20%, preferably 20%; the mass percentage concentration of the polyvinylpyrrolidone is 30-40%, preferably 40%.
Optionally, the mixing ratio in the fourth step can be set as 1:1:0, 1:1:0.2, 1:1:0.4, 1:1:0.6 and 1:1:0.8, and the conductivity, transparency, adhesion and mechanical properties of the final hydrogel can be adjusted by changing the ratio of the PDA NDs.
(2) The preparation of the hydrogel electrode comprises the following specific operation steps:
the hydrogel electrode comprises a protective film layer, a conductive hydrogel layer and a back lining layer from top to bottom. Pouring and cutting the prepared hydrogel into a specific shape to be used as a conductive hydrogel layer; mechanically coating the conductive hydrogel layer and a backing layer, and then pressing the conductive hydrogel layer and the backing layer together, wherein the backing layer is non-woven fabric, and preferably polypropylene and polyurethane adhesive; and covering a protective film layer on the conductive hydrogel layer, wherein the protective film layer is a polyethylene film.
Optionally, according to an embodiment provided by the present invention, the preparation process of the present invention includes: (1) preparing conductive hydrogel and (2) preparing hydrogel electrode. In the step (1), the conductive hydrogel is formed by covalent crosslinking through ketal reaction of linear polymers PVA and PVP after acid catalysis under heating condition, so that a skeleton network structure of the hydrogel is formed, and in the process, PVA and PVP are indispensable conditions; although PDA NDs are not necessary for forming hydrogel, conductive hydrogel with different properties can be obtained by changing the adding amount of the PDA NDs, namely the conductivity of the hydrogel is continuously adjustable within the range of 0.14-1.47S/m, the light transmittance of the hydrogel is continuously adjustable within the range of 91-98%, and the adhesive strength of the hydrogel and human tissues is continuously adjustable within the range of 29-42 kPa. In (2), the conductive hydrogel layer and the non-woven fabric layer are fixed together through mechanical pressing.
Example 1:
(1) preparation of the conductive hydrogel:
the method comprises the following steps: adding PVA into deionized water, and heating and stirring to dissolve the PVA to obtain a PVA solution with the mass concentration percentage of 20%;
step two: adding a certain amount of dopamine hydrochloride into a slightly alkaline Tris-HCl buffer solution, stirring for 12 hours in an open air to obtain a PDA solution, and then mixing and heating the PDA solution with a hydrogen peroxide/sodium hydroxide solution until a light yellow PDA NDs solution is obtained;
step three: uniformly mixing the PVA solution obtained in the step one and the PDA NDs solution obtained in the step two according to the volume ratio of 1: 0.4;
step four: adjusting the pH value of the mixed solution obtained in the third step to acidity, and heating.
Example 2:
(1) preparation of the conductive hydrogel:
the method comprises the following steps: adding PVP into deionized water, and dissolving by ultrasonic assistance to obtain a PVP solution with the mass concentration of 40%;
step two: adding a certain amount of dopamine hydrochloride into a slightly alkaline Tris-HCl buffer solution, stirring for 12 hours in an open air to obtain a PDA solution, and then mixing and heating the PDA solution with a hydrogen peroxide/sodium hydroxide solution until a light yellow PDA NDs solution is obtained;
step three: uniformly mixing the PVP solution obtained in the step one and the PDA NDs solution obtained in the step two according to the volume ratio of 1: 0.4;
step four: adjusting the pH value of the mixed solution obtained in the third step to acidity, and heating.
Example 3:
(1) preparation of the conductive hydrogel:
the method comprises the following steps: adding PVA into deionized water, and heating and stirring to dissolve the PVA to obtain a PVA solution with the mass concentration percentage of 20%;
step two: adding PVP into deionized water, and dissolving by ultrasonic assistance to obtain a PVP solution with the mass concentration of 40%;
step three: uniformly mixing the PVA solution obtained in the step one and the PVP solution obtained in the step two according to the volume ratio of 1: 1;
step four: adjusting the pH value of the mixed solution obtained in the third step to acidity, and heating.
Example 4:
(1) preparation of the conductive hydrogel:
the method comprises the following steps: adding PVA into deionized water, and heating and stirring to dissolve the PVA to obtain a PVA solution with the mass concentration percentage of 20%;
step two: adding PVP into deionized water, and dissolving by ultrasonic assistance to obtain a PVP solution with the mass concentration of 40%;
step three: adding a certain amount of dopamine hydrochloride into a slightly alkaline Tris-HCl buffer solution, stirring for 12 hours in an open air to obtain a PDA solution, and then mixing and heating the PDA solution with a hydrogen peroxide/sodium hydroxide solution until a light yellow PDA NDs solution is obtained;
step four: uniformly mixing the PVA solution obtained in the step one, the PVP solution obtained in the step two and the PDA NDs solution obtained in the step three according to the volume ratio of 1:1: 0.4;
step five: and (4) adjusting the pH value of the mixed solution obtained in the fourth step to be acidic, and heating.
Example 5:
(1) preparation of the conductive hydrogel:
the method comprises the following steps: adding PVA into deionized water, and heating and stirring to dissolve the PVA to obtain a PVA solution with the mass concentration percentage of 20%;
step two: adding PVP into deionized water, and dissolving by ultrasonic assistance to obtain a PVP solution with the mass concentration of 40%;
step three: adding a certain amount of dopamine hydrochloride into a slightly alkaline Tris-HCl buffer solution, stirring for 12 hours in an open air to obtain a PDA solution, and then mixing and heating the PDA solution with a hydrogen peroxide/sodium hydroxide solution until a light yellow PDA NDs solution is obtained;
step four: uniformly mixing the PVA solution obtained in the step one, the PVP solution obtained in the step two and the PDA NDs solution obtained in the step three according to the volume ratio of 1:1: 0.8;
step five: and (4) adjusting the pH value of the mixed solution obtained in the fourth step to be acidic, and heating.
Example 6:
(1) preparation of the conductive hydrogel:
the method comprises the following steps: adding PVA into deionized water, and heating and stirring to dissolve the PVA to obtain a PVA solution with the mass concentration percentage of 20%;
step two: adding PVP into deionized water, and dissolving by ultrasonic assistance to obtain a PVP solution with the mass concentration of 40%;
step three: adding a certain amount of dopamine hydrochloride into a slightly alkaline Tris-HCl buffer solution, stirring for 12 hours in an open air to obtain a PDA solution, and then mixing and heating the PDA solution with a hydrogen peroxide/sodium hydroxide solution until a light yellow PDA NDs solution is obtained;
step four: uniformly mixing the PVA solution obtained in the step one, the PVP solution obtained in the step two and the PDA NDs solution obtained in the step three according to the volume ratio of 1:1: 0.4;
step five: and (4) adjusting the pH value of the mixed solution obtained in the fourth step to be acidic, and heating.
(2) Preparation of hydrogel electrode:
in an alternative embodiment, the hydrogel electrode is formed as shown in fig. 1, and comprises a protective film layer, a conductive hydrogel layer and a non-woven fabric layer from top to bottom. The preparation method comprises the following steps: firstly, cutting the transparent self-adhesive conductive hydrogel obtained in the step (1) into a wafer with the diameter of 10mm and the thickness of 2mm, fixing the conductive hydrogel and the medical non-woven fabric through mechanical coating and pressing, and finally covering a polyethylene protective film on the conductive hydrogel layer.
Whether or not it is gelled | Conductivity (S/m) | Light transmittance (%) | Adhesive Strength (kPa) | |
Example 1 | Whether or not | / | / | / |
Example 2 | Whether or not | / | / | / |
Example 3 | Is that | 0.14±0.01 | 98.3±0.8 | 28.9±1.4 |
Example 4 | Is that | 0.71±0.02 | 94.8±2.1 | 41.7±3.0 |
Example 5 | Is that | 1.47±0.01 | 91.2±2.0 | 32.9±1.4 |
Comparing the results of examples 1 to 5, the results show that in the preparation process of the hydrogel electrode, the gel forming matrix is two linear polymers of PVA and PVP, and the two are indispensable components for forming the conductive hydrogel; the PDA NDs are used for enhancing the conductivity and tissue adhesion of the conductive hydrogel, and the transparency of the conductive hydrogel is influenced by the addition amount of the PDA NDs. Therefore, by changing the adding amount of the PDA NDs, the electric conductivity of the final hydrogel electrode can be regulated and controlled within the range of 0.14-1.47S/m, the adhesive strength can be regulated and controlled within the range of 29-42kPa, and the light transmittance can be regulated and controlled within the range of 91-98%.
As shown in figure 2, the prepared transparent self-adhesive conductive hydrogel has high transparency and tissue adhesion, and can firmly attach a small LED chip to an index finger.
As shown in figure 3, the prepared hydrogel electrode is quite mild, and does not cause allergic symptoms such as erythra, blisters and the like after being attached to a wrist for 24 hours.
As shown in fig. 4, the electromyographic sensor prepared using the above embodiment can accurately detect the surface electromyographic signal on the arm.
Compared with the traditional conductive hydrogel electrode, the conductive hydrogel electrode has the beneficial effects that: the transparent self-adhesive conductive hydrogel electrode is prepared by a simple method, all adopted materials are biocompatible materials, the materials are safe and mild, the conductivity, the adhesive property and the light transmittance of the hydrogel electrode can be regulated and controlled by the amount of the added PDA NDs, the operation is simple, the cost is low, and the transparent self-adhesive conductive hydrogel electrode has great practical production potential.
The above exemplary descriptions of the present invention are provided for further illustrating the preparation conditions and the application properties, and it is obvious to those skilled in the art that equivalent variations and modifications can be made without departing from the inventive concept of the present invention, and these are within the protection scope of the present invention.
Claims (10)
1. A transparent self-adhesive electrically conductive hydrogel electrode, comprising: the protective film layer, the conductive hydrogel layer and the back lining layer are sequentially arranged from top to bottom, the protective film layer is a polyethylene film, the conductive hydrogel layer is chemical crosslinking type hydrogel and is obtained by performing acid catalysis ketal reaction on polyvinyl alcohol and polyvinylpyrrolidone under a heating condition, the hydrogel is a three-dimensional network structure formed by polyvinyl alcohol and polyvinylpyrrolidone, and the back lining layer is non-woven fabric.
2. The transparent self-adhesive conductive hydrogel electrode according to claim 1, wherein the conductive hydrogel layer forms a conductive network by introducing PDA NDs, a derivative of polydopamine, and a Na + solution.
3. The transparent self-adhesive conductive hydrogel electrode according to claim 1, wherein the non-woven fabric is made of polypropylene or polyurethane glue.
4. The transparent self-adhesive conductive hydrogel electrode according to claim 1, wherein the conductive hydrogel layer is cast and cut into a specific shape for the hydrogel, and the conductive hydrogel layer and the backing layer are mechanically coated and then pressed together.
5. The transparent self-adhesive conductive hydrogel electrode according to claim 1, wherein the hydrogel has a conductivity in the range of 0.14 to 1.47S/m.
6. The transparent self-adhesive conductive hydrogel electrode according to claim 1, wherein the hydrogel has a light transmittance ranging from 91 to 98%.
7. The transparent self-adhesive conductive hydrogel electrode according to claim 1, wherein the hydrogel has an adhesive strength to human tissue in the range of 29-42 kPa.
8. A method for preparing the transparent self-adhesive conductive hydrogel electrode according to any one of claims 1 to 7, comprising: (1) preparing a hydrogel; (2) preparing a hydrogel electrode;
the preparation of the hydrogel (1) comprises the following steps:
the method comprises the following steps: adding polyvinyl alcohol (PVA) into deionized water, and heating and stirring to dissolve the PVA to obtain a PVA solution;
step two: adding polyvinylpyrrolidone (PVP) into deionized water, and dissolving with ultrasonic assistance to obtain a PVP solution;
step three: adding dopamine hydrochloride into a slightly alkaline Tris-HCl buffer solution, stirring for 12 hours in an open atmosphere to obtain a PDA solution, and then mixing and heating the PDA solution with a mixed solution of hydrogen peroxide and sodium hydroxide to obtain a polydopamine nanodot (PDA NDs) solution;
step four: uniformly mixing the PVA solution obtained in the first step, the PVP solution obtained in the second step and the polydopamine nanodot (PDA NDs) solution obtained in the third step according to a certain volume ratio;
step five: and C, adjusting the pH value of the mixed solution obtained in the fourth step to be acidic, and heating to obtain the hydrogel.
The (2) preparation of the hydrogel electrode comprises the following steps: pouring and cutting the prepared hydrogel into a specific shape to be used as a conductive hydrogel layer; mechanically coating the conductive hydrogel layer and a backing layer, and then pressing the conductive hydrogel layer and the backing layer together, wherein the backing layer is non-woven fabric; and covering a protective film layer on the conductive hydrogel layer, wherein the protective film layer is a polyethylene film.
9. The method for preparing the transparent self-adhesive conductive hydrogel electrode according to claim 8, wherein the concentration of the polyvinyl alcohol is 15-20% by mass; the mass percentage concentration of the polyvinylpyrrolidone is 30-40%.
10. The method for preparing the transparent self-adhesive conductive hydrogel electrode according to claim 9, wherein the concentration of the polyvinyl alcohol is 20% by mass; the mass percentage concentration of the polyvinylpyrrolidone is 40%.
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CN103908682B (en) * | 2014-04-29 | 2016-08-24 | 中国科学院长春应用化学研究所 | The application of poly-dopamine nanoparticle |
CN105153359B (en) * | 2015-08-25 | 2018-02-23 | 康柏医疗器械(惠州)有限公司 | A kind of conductive hydrogel and conductive hydrogel coiled material and preparation method thereof |
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CN107129573B (en) * | 2017-06-26 | 2020-02-07 | 中国科学院宁波材料技术与工程研究所 | Diamond-reinforced polyimide nano composite material and preparation method and application thereof |
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CN110117369B (en) * | 2019-05-16 | 2022-03-01 | 吉林大学 | Antibacterial adhesive conductive hydrogel and preparation method and application thereof |
CN110384654B (en) * | 2019-07-10 | 2022-04-01 | 浙江理工大学 | Preparation method of controlled-release hydrogel with photothermal treatment and wound repair functions |
CN110496609B (en) * | 2019-09-25 | 2022-04-22 | 青岛科技大学 | Graphene oxide/hydroxyapatite nanowire multifunctional adsorption aerogel and preparation method thereof |
CN111790005A (en) * | 2020-07-16 | 2020-10-20 | 复旦大学 | Polydopamine-modified artificial ligament and modification method thereof |
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2020
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