CN112450923A - Method for detecting performance of sensor - Google Patents

Method for detecting performance of sensor Download PDF

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Publication number
CN112450923A
CN112450923A CN202010856740.0A CN202010856740A CN112450923A CN 112450923 A CN112450923 A CN 112450923A CN 202010856740 A CN202010856740 A CN 202010856740A CN 112450923 A CN112450923 A CN 112450923A
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CN
China
Prior art keywords
sensor
detection
reagent
module
motor
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Pending
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CN202010856740.0A
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Chinese (zh)
Inventor
马千理
丁建林
张文伶
杨清刚
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Hangzhou Weice Biotechnology Co ltd
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Hangzhou Weice Biotechnology Co ltd
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Application filed by Hangzhou Weice Biotechnology Co ltd filed Critical Hangzhou Weice Biotechnology Co ltd
Priority to CN202010856740.0A priority Critical patent/CN112450923A/en
Publication of CN112450923A publication Critical patent/CN112450923A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1486Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using enzyme electrodes, e.g. with immobilised oxidase
    • A61B5/14865Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using enzyme electrodes, e.g. with immobilised oxidase invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1495Calibrating or testing of in-vivo probes

Abstract

The invention discloses a method for detecting the performance of a sensor, which comprises the following steps: (1) placing the sensor in a sensor placing plate; (2) reading sensor data; (3) selecting sensor detection parameters, and (4) putting corresponding detection reagents; (5) selecting a detection scheme, wherein the detection scheme comprises static detection, vibration detection, vortex detection, reciprocating detection and composite detection; (6) carrying out real-time detection; (7) and displaying the real-time detection result. The detection method of the invention enables the sensor to finish detection in a dynamic environment, compared with static detection, the dynamic environment of the invention is closer to the environment in human body, the detection result is more accurate, the error is smaller when repeated detection is carried out, and the detection and the performance evaluation of the sensor are facilitated; the detection method can detect various properties of the sensor, such as sensitivity, service life, mechanical property, repeatability precision and corrosion resistance.

Description

Method for detecting performance of sensor
Technical Field
The invention relates to the field of blood glucose monitoring, in particular to a method for detecting sensor performance.
Background
The dynamic blood sugar monitor (CGMS) is one of diagnosis and treatment instruments in the endocrinology department, and is used for collecting dynamic blood sugar change data of diabetics for multiple days and serving as a monitoring tool of a blood sugar map. Through the instrument, doctors can comprehensively know the blood sugar fluctuation type and the trend of patients, and the instrument has great significance for blood sugar control and diabetes treatment. The dynamic blood sugar detector consists of a glucose emitter and a blood sugar recorder, wherein the emitter is internally provided with a sensor which can be implanted under the skin, has the characteristics of strong detection function, small volume, convenient use, little pain and the like, and can accurately master the blood sugar condition of patients with abnormal blood sugar and complicated illness. Glucose oxidase contained in the sensor placed under the skin and glucose in subcutaneous interstitial fluid are subjected to chemical reaction, and the generated electric signal is transmitted to analysis software by the sensor through an emitter and then converted into a blood glucose value.
Because the sensor needs to be implanted into a human body, the contact period of the sensor with the human body is long (about 20 days); this requires a long service life of the sensor; part of patients have rejection reaction and pain to the sensor, so that the sensor is required to have better biocompatibility and mechanical property; in addition, the sensitivity of the sensor to the reaction of substances in the human body, the repeatability accuracy of the sensor, the corrosion resistance and other properties are also important. Therefore, it is necessary to detect the performance of the sensor. There is a need to establish a feasible detection method. And no detection standard is formed in the market at present.
At present, when the performance of a sensor is generally detected, a static detection mode is adopted, namely, in the detection process, relative motion does not exist between the sensor and a reagent, so that the accuracy of the detected data is low, and the error is large when repeated detection is carried out; moreover, the sensor parameters that can be detected are limited and the detection period is long. In the static detection mode, the detection environment of the sensor is greatly different from the environment in the human body, the accuracy is low, and the detection of the sensor in the human body cannot be truly simulated.
Disclosure of Invention
In view of the above, the present invention provides a method for detecting sensor performance to overcome the drawbacks of the prior art.
In order to achieve the purpose, the invention provides the following technical scheme:
a method of detecting sensor performance, comprising the steps of:
(1) placing the sensor in a sensor placing plate;
(2) reading sensor data;
(3) the sensor is selected to detect the parameter(s),
(4) putting corresponding detection reagents;
(5) selecting a detection scheme, wherein the detection scheme comprises static detection, vibration detection, vortex detection, reciprocating detection and composite detection;
(6) carrying out real-time detection;
(7) and displaying the real-time detection result.
Further, in step (2), the sensor data includes the model of the sensor, the number of sensors, and other information indicating the sensors.
Further, in the step (3), the detection parameters of the sensor include sensitivity, service life, mechanical properties, repeatability precision and corrosion resistance.
Further, in the step (6), the specific process of performing the static detection is as follows: the second motor works to drive the first synchronous wheel, the synchronous belt and the second synchronous wheel to move, the sensor pressing plate rotates, the sensor placing plate rotates, the included angle between the sensor pressing plate and the sensor placing plate is reduced, and finally the sensor pressing plate fixes the sensor; according to the position of the sensor, the fourth motor works to drive the second screw rod to rotate, so that the reagent box moves backwards or forwards to a working position; the first motor works to drive the first screw rod to rotate, the first screw rod sleeve and the mounting plate move downwards, and the sensor moves downwards along with the first screw rod sleeve until the sensor is immersed in a reagent to perform detection.
Further, in the step (6), the vibration detection process includes: on the basis of static detection, the sensor reciprocates upwards and downwards in the reagent; or/and the sensor reciprocates back and forth in the reagent.
Further, in the step (6), the specific process of the upward or downward movement of the sensor in the reagent is as follows: the first motor rotates to drive the first screw rod to rotate, the first screw rod sleeve and the mounting plate move downwards or upwards, the sensor moves downwards or upwards in the reagent along with the mounting plate, and the sensor completes detection in the process of moving upwards or downwards.
Further, in step (6), the specific process of the sensor moving forwards or backwards in the reagent is as follows: the fourth motor rotates to drive the second screw rod to rotate, the second screw rod sleeve and the reagent box move forwards or backwards, the reagent moves forwards or backwards along with the reagent box, and the sensor completes detection in the process that the reagent moves forwards or backwards.
Further, in the step (6), the specific process of performing vortex detection is as follows: on the basis of static detection, the third motor works to drive the second gear to rotate, the first gear rotates along with the second gear, the reagent box connected with the first gear rotates, a vortex is generated in a reagent, and the sensor detects in a vortex state.
Further, in the step (6), the process of performing the reciprocating detection is consistent with the process of detecting the vibration, but the motion amplitude of the vibration detection is smaller than that of the reciprocating detection, and the frequency of the vibration detection is lower than that of the reciprocating detection.
Further, in the step (6), the specific process of performing the composite detection is as follows: on the basis of static detection, reciprocating detection and vortex detection are carried out simultaneously.
The invention has the beneficial effects that:
(1) the detection method of the invention enables the sensor to finish detection in a dynamic environment, compared with static detection, the dynamic environment of the invention is closer to the environment in human body, the detection result is more accurate, the error is smaller when repeated detection is carried out, and the detection and the performance evaluation of the sensor are facilitated; the detection method can detect various properties of the sensor, such as sensitivity, service life, mechanical property, repeatability precision and corrosion resistance.
(2) The detection method has the advantages of high automation degree, simple operation and high detection efficiency, can be suitable for sensors with different specifications, and can carry out batch detection.
Drawings
FIG. 1 is a schematic view of the structure of the detecting device of the present invention.
FIG. 2 is a schematic view of the back side of the detecting device of the present invention.
Fig. 3 is a schematic diagram of data transmission relationship between modules.
Fig. 4 is a schematic structural diagram of a transmission module.
Fig. 5 is a schematic diagram of a wireless transmitter installation.
Fig. 6 is a schematic diagram of the wireless transmission circuit board mounted on the sensor pressing plate, wherein (a) is a schematic diagram of the back structure of the sensor pressing plate, and (b) is a schematic diagram of the front structure of the sensor pressing plate.
Fig. 7 is a schematic structural diagram of an interaction module, where (a) is a schematic structural diagram of a front side of a touch screen, and (b) is a schematic structural diagram of a back side of the touch screen.
Fig. 8 is a schematic diagram of data transmission relationship between the interactive module and other modules.
Fig. 9 is a schematic diagram of the line connections between the interactive module and other modules.
Fig. 10 is a schematic structural view of the front side of the sensor module.
Figure 11 is a schematic side view of the sensor module (showing the timing belt and the timing wheel).
Fig. 12 is a schematic view of a mounting structure of the spring contact.
Fig. 13 is a cross-sectional view of fig. 12.
Fig. 14 is a schematic view showing a connection relationship between the sensor placement board and the sensor pressing board.
Fig. 15 is an exploded view of the securing mechanism.
Fig. 16 is an exploded view of the height adjustment device.
Fig. 17 is a schematic diagram showing the installation of the sensor module, wherein (a) is a schematic diagram showing the structure of the back surface of the detection device after the installation of the sensor module, and (b) is a schematic diagram showing the structure of the side surface of the detection device after the installation of the sensor module.
Fig. 18 is a schematic view of the structure of the height adjusting means when the first motor is operated.
Fig. 19 is a schematic view of the fixing mechanism in operation of the second motor.
Fig. 20 is a schematic view of the fixing mechanism when the angle between the sensor pressing plate and the sensor placing plate is 90 degrees.
Fig. 21 is a schematic view of the fixing mechanism when the angle between the sensor pressing plate and the sensor mounting plate is 70 degrees.
Fig. 22 is a schematic view of the fixing mechanism when the angle between the sensor pressing plate and the sensor mounting plate is 0 degree.
Fig. 23 is a schematic structural view of the sensor module when the included angle between the sensor pressing plate and the sensor placing plate is 0 degree.
FIG. 24 is a schematic diagram of the structure of a reagent module.
Figure 25 is a reagent module installation diagram.
Fig. 26 is a schematic structural view of a power supply module.
Fig. 27 is a schematic structural diagram of a control module.
Fig. 28 is a schematic structural view of the drive module.
Fig. 29 is a schematic structural view of a frame module.
Fig. 30 is an exploded view of the detection device of the present invention.
Fig. 31 is a schematic view of a sensor detection process.
FIG. 32 is a schematic view of a reagent detection process.
FIG. 33 is a diagram illustrating the display content of the touch screen during the sensor detection process.
Fig. 34 is a schematic view showing the display content of the touch screen during the sensor detection process (showing the detection result).
Fig. 35 is a schematic diagram of a sensor structure in which (a) is a single sensor structure and (b) is a structure in which a plurality of sensors are connected in parallel.
Fig. 36 is a schematic structural view of a sensor placement board, in which (a) is a schematic side structural view of the sensor placement board, and (b) is a schematic front structural view of the sensor placement board.
FIG. 37 is a schematic view of a square kit; wherein (a) is a cross-sectional view of the square kit, and (b) is a top view of the square kit.
Fig. 38 is a schematic structural view of a round-shaped reagent cartridge, in which (a) is a sectional view of the reagent cartridge and (b) is a schematic structural view of the inside of the reagent cartridge.
Fig. 39 is a schematic view showing a connection relationship between the sensor and the sensor placement board, in which (a) is a schematic view showing a structure in which the sensor and the sensor placement board are separated from each other, and (b) is a schematic view showing a structure in which the sensor and the sensor placement board are combined.
FIG. 40 is a schematic view of the cartridge in connection with the first gear.
FIG. 41 is a schematic diagram of the structure of the device of the present invention prior to detection of sensor performance.
FIG. 42 is a schematic structural view of the detecting device of the present invention when the included angle between the sensor pressing plate and the sensor placing plate is 0 degree.
FIG. 43 is a schematic view showing the structure of the detecting unit of the present invention when the position of the reagent cartridge is adjusted.
FIG. 44 is a schematic view showing the structure of the detecting unit of the present invention in the process of inserting the sensor into the reagent.
FIG. 45 is a schematic view showing the structure of the detecting unit of the present invention in the case of still detection.
FIG. 46 is a schematic view showing the structure of the detecting unit of the present invention in vibration detection.
FIG. 47 is a schematic view of the detecting unit of the present invention in the case of vortex detection.
FIG. 48 is a schematic view showing the structure of the detecting unit of the present invention in the case of multiplex detection.
FIG. 49 is a schematic configuration diagram of another embodiment of a reagent site adjustment apparatus.
FIG. 50 is a schematic structural diagram of another embodiment of the reagent position adjusting apparatus (showing the relative positional relationship among gears, motors, conveyor belts, and sliders).
Fig. 51 is a side view of fig. 49.
Detailed Description
The technical solutions of the present invention are further described in detail below with reference to the accompanying drawings, and it should be noted that the detailed description is only for describing the present invention, and should not be construed as limiting the present invention. The motor described below is mainly used for supplying power, and other devices capable of supplying power may be applied to the present invention, and the present invention is not limited to the device for supplying power.
Example 1
As shown in fig. 1-2, a multi-channel detection device includes a transmission module 1, an interaction module 2, a sensor module 3, a reagent module 4, a power supply module 5, a control module 6, a driving module 7, and a frame module 8. The transmission module 1, the interaction module 2, the sensor module 3, the reagent module 4, the power supply module 5, the control module 6 and the driving module 7 are respectively connected with the frame module 8.
In some preferred modes, as shown in fig. 3, the transmission module 1 can recognize signals from the sensor module 3 and the reagent module 4 and can feed the signals back to the control module 6, the control module 6 can transmit the signals to the interaction module 2, the interaction module 2 displays corresponding data, the control module 6 can also receive the signals from the interaction module 2, the control module 6 can control the driving module 7 to move, and the power supply module 5 supplies power to the whole device. The transmission module 3 is also capable of transmitting data to the outside or receiving data from the outside.
In some preferred forms, as shown in fig. 29, the frame module 8 is composed of a left side plate 39, a right side plate 40, a back plate 41, a top plate 42, a partition plate 43, and a bottom plate 222, and the final assembly effect is shown in fig. 1.
In some preferred modes, as shown in fig. 10 to 11, the sensor module 3 comprises a fixing mechanism for mounting and fixing the sensor, a height adjusting device for adjusting the vertical distance between the sensor and the detection reagent, and a collecting device for collecting the sensor signal.
In some preferred manners, as shown in fig. 10 to 11, the height adjusting device includes a first motor 121, a first coupling 123, a first lead screw 124, and a mounting plate 128, wherein the first motor 121 is connected to the first coupling 123, the first coupling 123 is connected to the first lead screw 124, the first lead screw 124 is directly or indirectly connected to the mounting plate 128, and the sensor placing plate can be directly or indirectly mounted on the mounting plate. The first motor 121 can provide power, and the first coupling 123 connects the first motor 121 and the first lead screw 124 together to transmit motion and power. If the first motor 121 is activated, the first lead screw 124 can be rotated therewith. In other modes, instead of the first lead screw 124, a gear and a toothed plate can be combined to adjust the height of the sensor. In some preferred manners, the first motor 121 can drive the first lead screw 124 to perform clockwise or counterclockwise motion; programmable electrical pulse signals are input into the motors, so that the first motor 121 has two motion modes of uniform speed and variable speed. The motor used in the invention can adopt the motor and the coupler in the prior art, and the invention does not improve the structure and the working principle of the motor and the coupler.
In some preferred forms, as shown in fig. 10 to 11, the height adjustment device further includes a first motor bracket 120, the first motor 121 can be mounted on the first motor bracket 120, and the first motor bracket 120 can be fixed to the frame module 8, so that the first motor 121 can be fixed.
In some preferred forms, as shown in fig. 10-11, the height adjustment device further includes a first screw sleeve 127, the first screw sleeve 127 is matched with the first screw 124, the first screw sleeve 127 can be mounted on other components, in this embodiment, the first screw sleeve 127 is mounted and fixed on the mounting plate 128; the first lead screw 124 can rotate in the first lead screw sleeve 127, and when the first lead screw 124 rotates, the first lead screw sleeve 127 can perform a linear motion along the first lead screw 124, and the mounting plate 128 performs a linear motion therewith (for example, the first lead screw sleeve 127 and the mounting plate 128 can move downward or upward along the first lead screw 124, and the clockwise or counterclockwise motion of the first lead screw 124 determines whether the first lead screw sleeve 127 and the mounting plate 128 move upward or downward).
In some preferred forms, as shown in fig. 10-11, the height adjustment device further includes a stop assembly that limits the maximum distance the mounting plate 128 can move up or down to avoid excessive upward movement of the mounting plate 128 that could contact and wear the first coupling 123, and also to avoid excessive downward movement of the mounting plate 128 that could disengage the first lead screw 124.
In some preferred forms, as shown in fig. 10, the limiting assembly includes a polish rod 125, a polish rod sleeve 126 and a supporting seat 122, the polish rod 125 is sleeved with the polish rod sleeve 126, and the supporting seat 122 is connected with the polish rod 125, in this embodiment, as shown in fig. 16, the polish rod 125 can be inserted into the polish rod sleeve 126 and can be inserted into an opening of the supporting seat 122 to a step surface, and then the polish rod 125 and the supporting seat 122 are locked by a set screw 111 to fixedly connect the polish rod 125 with the supporting seat 122. In some preferred forms, as shown in fig. 10-11, the polish rod sleeve 126 is mounted and fixed to the mounting plate 128, and two bearings 122 are attached to the ends of the polish rod 125 above and below the mounting plate 128, respectively, the upper bearing 122 being capable of restraining the mounting plate 128 against unlimited upward movement and the lower bearing 122 being capable of restraining the mounting plate 128 against unlimited downward movement. In some preferred forms, as shown in fig. 17, the support base 122 may be fixed to the frame module 8 by a set screw 111. In this embodiment, the shaft coupling can the flexible compensation motor with the installation error of lead screw, avoids power device and lead screw to cause the motion card to pause, the card is dead because of installation error, avoids power device to cause the burnout because of the torque is unbalanced.
The motor 121 is started to drive the first coupler 123 to rotate, the first coupler 123 drives the first lead screw 124 to rotate, the first lead screw sleeve 127 and the mounting plate 128 can make upward or downward linear reciprocating motion, the supporting seats 122 at the two ends of the polished rod 125 are mechanical limiting, the number of rotating circles of the motor is defined in the control module to be used as software limiting, the number of rotating circles of the motor is limited, the number of rotating circles of the first coupler is further controlled to be converted into linear length, and the general software limiting distance is smaller than or equal to the mechanical limiting distance, and in some preferred modes, the movement range of the mounting plate is 0-25 mm. In some preferred forms, the motor 121 is a stepper motor, and the first lead screw 124 and the first lead screw sleeve 127 are ball screws. The stepping motor can realize accurate control according to the constant rotation characteristic of the stepping angle; the ball screw can realize higher displacement precision and transmission efficiency, extremely low shaking coefficient and frictional resistance and higher repeated positioning precision during reciprocating movement. The ball screw used in the invention is available, and the invention does not improve the structure and the working principle of the ball screw.
In some preferred modes, the fixing mechanism comprises a sensor placing plate 134 and a sensor pressing plate 135, the sensor placing plate 134 can be used for installing and placing the sensor 133, the sensor pressing plate 135 can be used for fixing and pressing the sensor 133, and the sensor placing plate 134 is connected with the sensor pressing plate 135, and in some preferred modes, the sensor placing plate 134 and the sensor pressing plate 135 are connected together through a connecting shaft, similar to hinge type connection. In this embodiment, as shown in fig. 14, the convex portion of the sensor placement plate 134 is fitted into the concave portion of the sensor holding plate 135 in the 1 direction, and then the third shaft 141 is inserted into the shaft hole in the 2 direction, so that the sensor placement plate 134 is coupled to the sensor holding plate 135, and the sensor placement plate 134 can hinge-move in the range of 0 to 90 degrees along the third shaft 141. An included angle between the sensor placing plate 134 and the sensor pressing plate 135 may be 0 to 90 degrees, and when the included angle between the sensor placing plate 134 and the sensor pressing plate 135 is 0 degree, as shown in fig. 23, the sensor pressing plate 135 compresses and fixes the sensor 133 on the sensor placing plate 134, so as to prevent the sensor 133 from loosening and falling off from the sensor placing plate 134; when the angle between the sensor placement plate 134 and the sensor pressing plate 135 is 90 degrees, as shown in fig. 10, it is easy to place and mount the sensor 133 on the sensor placement plate 134 and to detach the sensor 133 from the sensor placement plate 134.
In some preferred forms, the sensor pressure plate 135 is connected to the mounting plate 128, and in some preferred forms, the sensor pressure plate 135 and the mounting plate 128 are hingedly connected together by a connecting shaft, similar to a hinge-type connection. In this embodiment, as shown in fig. 15, the mounting plate 128 and the sensor pressure plate 135 are connected by fitting the convex portion of the sensor pressure plate 135 into the concave portion of the mounting plate 128 and then inserting the second shaft 137 into the shaft hole, and the sensor pressure plate 135 can rotate relative to the mounting plate 128 about the second shaft 137. When the mounting plate 128 moves up or down along the first lead screw 124, the sensor pressing plate 135 and the sensor placing plate 134 can move up or down, so that the height of the sensor can be changed, and the distance from the sensor to the reagent can be changed.
In some preferred manners, the sensor placement board 134 is fixedly or indirectly connected to the mounting board 128, and in this embodiment, as shown in fig. 10 and 15, the two are connected together by a connecting rod 136, one end of the connecting rod 136 is connected to the sensor placement board 134, and the other end is connected to the mounting board 128. The projection at the end of the connecting rod 136 can be inserted into the groove on the mounting plate 128 to realize clamping, and the projection at the end of the connecting rod 136 can rotate in the groove and cannot be disengaged. Similarly, the projection of the other end of the link 136 can be coupled to the recess provided in the sensor placement plate 134, and the projection can also be rotated in the recess without being disengaged.
In some preferred forms, as shown in fig. 11, the fixing mechanism further comprises a second motor 140, the second motor 140 being capable of providing power, and in some preferred forms, the second motor 140 being capable of providing both clockwise and counterclockwise motion; two motion modes of uniform speed and variable speed. Specifically, the second motor 140 can change the distance between the sensor pressing plate 135 and the sensor placing plate 134, so that the included angle between the sensor placing plate 134 and the sensor pressing plate 135 can be 0 to 90 degrees, the sensor can be automatically fixed or released, the degree of automation is high, and manual fixing is not needed.
In some preferred forms, the second motor 140 may be fixedly mounted on the mounting plate 128, and in this embodiment, as shown in fig. 15 and 19, the second motor 140 is first connected to the second motor bracket 142, and then the second motor bracket 142 is fixedly mounted on the mounting plate 128.
In some preferred manners, the second motor 140 is connected to the sensor pressure plate 135 through a timing belt 138 and a timing wheel, so as to transmit power to the second shaft 137 and the sensor pressure plate 135 to realize a rotary motion. In some preferred forms, as shown in fig. 15 and 19, the first synchronizing wheel 139 is connected to the second motor 140, the second synchronizing wheel 1391 is connected to the sensor pressure plate 135, the second synchronizing wheel 1391 is connected to the second shaft 137, and the sensor pressure plate 135 is also connected to the second shaft 137; second motor 140 rotates, can drive first synchronizing wheel 139 and rotate, and then drive second synchronizing wheel 1391 through the transmission of drive belt and rotate, correspondingly, second axle 137 rotates, and sensor clamp plate 135 rotates thereupon, and the board 134 rotation is placed to the sensor, finally can realize that sensor clamp plate 135 compresses tightly, the fixed sensor places board 134, the purpose of fixed sensor.
In some preferred embodiments, as shown in fig. 20-21, the sensor placement plate 134 rotates about the third axis 141(O3) relative to the sensor pressure plate 135, and when the back surface of the sensor placement plate 134 contacts the side surface of the boss of the sensor pressure plate 135, the sensor placement plate 134 cannot rotate clockwise due to mechanical limitations, and the included angle between the sensor placement plate 134 and the sensor pressure plate 135 is 90 ° at the maximum, and the mechanism is in the open state, as shown in fig. 20. (the number of motor revolutions is defined as a software limit in the control module system program) this avoids excessive counterclockwise or clockwise rotation of the sensor placement plate 134, resulting in a poor sensor fixation.
As shown in fig. 21, the first timing wheel 139 rotates clockwise about the first axis O1, the second timing wheel 1391 rotates clockwise about the second axis 137(O2) by transmission of the timing belt 138, the sensor pressure plate 135 rotates clockwise about the second axis 137(O2) with respect to the mounting plate 128, and the sensor placement plate 134 rotates counterclockwise about the third axis 141(O3) with respect to the mounting plate 128. The included angle between the sensor placing plate 134 and the sensor pressing plate 135 is reduced, and the fixing mechanism is in a transition state.
As shown in fig. 22, when the first synchronous wheel 139 continues to rotate clockwise for a certain number of turns around the first axis O1, due to a mechanical limit (the number of turns of the motor can be defined as a software limit in the control module system program), the sensor placing plate 134 cannot rotate counterclockwise, the angle between the sensor placing plate 134 and the sensor pressing plate 135 is 0 °, and the fixing mechanism is in a closed state.
In some preferred forms, the fixing mechanism further includes a collecting device, the collecting device includes a sensor circuit board 130, the sensor circuit board 130 is connected to the sensor pressing plate 135, in some preferred forms, as shown in fig. 12 to 13, the sensor circuit board 130 is fixed on the upper surface of the sensor pressing plate 135 by using a hexagon stud 131 and a set screw, and in other forms, the fixing mechanism may be fixed by using a snap-in connection or a screw. In some preferred forms, as shown in fig. 10, a connection terminal 132 is connected to the upper surface of the sensor circuit board 130, and a connection port is provided on the connection terminal 132. In some preferred forms, spring contact 1321 is connected to sensor circuit board 130, spring contact 1321 can be used to connect to sensor contact 1326, and thus transmit a sensing signal, in some preferred forms, as shown in fig. 12-13, spring contact 1321 is fixed between sensor circuit board 130 and sensor pressure plate 135, the upper end of spring contact 1321 is located in the upper counterbore of sensor circuit board 130, the lower end of spring contact 1321 is located in the lower counterbore of sensor pressure plate 135, in some preferred forms, the counterbore on sensor pressure plate 135 includes two different sections, the first section is larger than the second section, so that the lower end of spring contact 1321 can extend out of sensor pressure plate 135, and the length of spring contact 1321 extending out of sensor pressure plate 135 can be limited. In some preferred forms, spring contacts 1321 are standard components, known in the art, and are commercially available with internal structure and travel shown in fig. 13.
In the prior art, as shown in fig. 35, the sensor includes an upper segment 1322, a middle segment 1323 and a lower segment 1324, the middle segment 1323 is used as a transition segment to connect the upper segment 1322 and the lower segment 1324 together. The upper end of upper segment 1322 is equipped with insulating layer 1325, and the surface region of upper segment 1322 is equipped with contact 1326, can be connected with elastic contact 1321, and lower segment 1324 is the detection segment, as effective reaction length, and the model of the sensor that awaits measuring is different, and effective reaction length is different. Generally, the sensors are small and irregular in shape, and it is not easy to put the sensors in the sensor placement board 134.
In the invention, the sensors are connected in parallel, specifically, as shown in fig. 35, the insulating layer 1325 at the upper end of each sensor is connected with the insulating rod 1327, when the sensors need to be placed, the sensors only need to be held by the insulating rod 1327 and correspondingly installed on the sensor placing plate 134, the operation is simple and quick, so that a plurality of sensors can be placed in the sensor placing plate 134 at one time, the sensors can be placed in batch, and the working efficiency is improved. In some preferred forms, each sensor is removably attached to the insulating rod 1327, such as by snapping, to facilitate removal of the sensor. In a specific case, a corresponding number of sensors can be placed according to requirements, and the number of the sensors can be one or more than two. In this embodiment, 8 sensors are connected to the insulating rod 1327.
In some preferred forms, as shown in fig. 39, the sensor mounting plate 134 is provided with a lateral catching slot 1328 on its surface for catching the insulating rod 1327. In some preferred manners, as shown in fig. 36, the sensor placement board 134 is further provided with a slot 1329 on the surface, and the slot 1329 facilitates the placement of the sensor and can fix the sensor so that the sensor is in a fixed state to prevent the sensor from tilting or separating from the sensor placement board 134. In some preferred forms, the slot 1329 is shaped to match the shape of the sensor, in some preferred forms, the slot 1329 is shaped like a "Y", and in some preferred forms, the open end of the slot 1329 is provided with a positioning surface 1330, and the positioning surface 1330 can fix the upper segment 1322 of the sensor when the sensor is placed in the slot 1329. In some preferred manners, a sensor 1331 is further disposed on the sensor placement board 134, and the sensor 1331 can read information of the type, number, placement position, and the like of the sensors.
In some preferred forms, as shown in fig. 14, a protrusion 1332 is formed on the lower surface of the sensor pressing plate 135 and can be caught at the lower portion of the slot 1329, so that the sensor pressing plate 135 can be tightly combined with the sensor placing plate 134, and the elastic contact 1321 is in contact connection with the sensor contact 1326.
In some preferred modes, as shown in fig. 6, the wireless transmission circuit board 100 in the transmission module 1 is mounted on the back of the sensor pressing plate 135, so as to transmit the sensor signal, and in some preferred modes, the sensor pressing plate 135 is provided with an opening, so that the quick connector 101 extends out of the sensor pressing plate 135 and is inserted into the connection port on the connection terminal 132.
Generally, the sensor is placed on the sensor placement board 134, and then the sensor pressing board 135 presses the sensor placement board 134, at this time, the elastic contact 1321 is in contact with the sensor contact 1326 and can transmit a signal to the sensor circuit board 130, and the sensor circuit board 130 transmits the sensor signal to the wireless transmission circuit board 100 through the connection terminal 132.
In some preferred modes, the reagent module 4 comprises a reagent containing device, a vortex generating device and a reagent position adjusting device, wherein the reagent containing device can be used for containing a reagent for detection; the vortex generating device is configured to enable the reagent in the kit to generate a vortex and mix the reagent uniformly, so that the mechanical property and the repeatability of the sensor can be conveniently tested, and the test result is more accurate. And the reagent position adjusting device is configured to be capable of adjusting the position of the reagent containing device so as to adjust the position of the reagent.
In some preferred forms, the reagent holding means comprises a reagent cartridge comprising a plurality of reagent holding recesses. As shown in fig. 24, the reagent cartridge may be a square reagent cartridge 200, or a round reagent cartridge 201, or in another preferred embodiment, an eccentric reagent cartridge may be used; the shape of the kit is not limited in the present invention, and any one of the kit may be selected according to actual needs in the specific implementation. The groove for holding the reagent can be a cylindrical groove or a groove similar to a centrifugal tube, so that the use amount is small, and the groove can be in other shapes. In some preferred embodiments, as shown in fig. 37, the reagent box is a square reagent box 200, and the reagent box 200 has a plurality of cylindrical recesses for holding reagents, and the plurality of cylindrical recesses are separated from each other and independent of each other.
In other preferred modes, as shown in fig. 38, the reagent cartridge 201 includes a plurality of circles of annular grooves 2011, the circle centers of the annular grooves 2011 are the same, and reagents can be stored in the annular grooves 2011. Different annular recesses 2011 may store the same reagent or different reagents therein. The annular groove 2011 can be used for storing a certain amount of reagents, is convenient for adding the reagents, and is beneficial to oscillation and uniform mixing of the reagents. In some preferred modes, as shown in fig. 38, a reagent induction ring 2012 is disposed in the annular groove 2011 for detecting the amount of the reagent, and whether the amount of the reagent is sufficient for the detection test.
In some preferred ways, as shown in fig. 37, a reagent sensor 2013 is provided in the groove for holding the reagent, and the reagent sensor 2013 can be used to detect whether the correct reagent is placed at the corresponding position; the reagent induction loop 2012 can be used to detect whether a sufficient amount of reagent is placed at the corresponding location. The reagent induction ring 2012 and the reagent inductor 2013 can transmit the induction data to the transmission module 1 wirelessly. In other preferred forms, as shown in fig. 37(a), a sensing circuit board 2014 is provided at the bottom of the reagent cartridge, and the sensing circuit board 2014 can be used for receiving sensing data of a plurality of reagent sensors 2013 and reagent sensing rings 2012 and sending the sensing data to the control module 6. Reagent induction ring 2012, reagent inductor 2013, response circuit board 2014 all exist among the prior art, can buy.
In some preferred forms, as shown in fig. 24, the vortex generating means comprises a third motor 206, a first gear 203, a second gear 204, and a tray 202. In some preferred modes, the third motor 206 is fixedly connected with the tray 202, the second gear 204 is connected with the third motor 206, the first gear 203 is in contact and meshed connection with the second gear 204, and the first gear 203 is installed on the fixed tray 202. In this embodiment, as shown in fig. 24, an outer cylindrical surface of the third motor 206 is screwed into a corresponding threaded hole on the tray 202 until the stepped surface is fixed, the second gear 204 and the first gear 203 are respectively inserted into a rotating shaft of the third motor 206 and a boss of the tray 202, and are connected and fixed, and the gear set (the second gear 204 and the first gear 203) can move in a meshing manner; in some preferred modes, the reagent cartridge 201 is fixedly connected with the first gear 203, and as shown in fig. 40, the center of the reagent cartridge 201 is connected with the center of the first gear 203 through a screw. In other preferred embodiments, the reagent cartridge 201 and the first gear 203 are connected by a snap-in connection. When the third motor 206 is started, the second gear 204 rotates, the first gear 203 also rotates, and accordingly the reagent kit 201 rotates along with the second gear, so that the reagent in the reagent kit 201 can generate vortexes, the reagents are uniformly mixed, the vortexes can be conveniently detected, and the mechanical property and the repeatability of the sensor can be conveniently detected. In some preferred modes, the reference circle diameter of the first gear is larger than that of the second gear, so that the contact area of the first gear and the reagent kit is larger, the reagent kit can be better supported, and the reagent kit is driven to rotate. Of course, the pitch circle diameters of the first gear and the second gear may be equal or the pitch circle diameter of the first gear may be smaller. In some preferred modes, the height of the first gear is higher than that of the second gear, so that the first gear does not interfere with the second gear when the first gear drives the reagent kit to rotate.
In other preferred forms, only one gear 204 is used, the gear 204 being connected to the reagent cartridge; third motor 206 rotates, can drive gear 204 and rotate, and the kit that is connected with gear 204 can rotate to the reagent mixing.
In some preferred modes, as shown in fig. 24, the reagent position adjusting means includes a fourth motor 221, a second lead screw 213, and a second coupling 219. The fourth motor 221 is connected with a second coupling 219, the second coupling 219 is connected with the second lead screw 213, the fourth motor 221 can provide power, and the second coupling 219 connects the fourth motor 221 with the second lead screw 213 to transmit motion and power. If the fourth motor 221 is activated, the second lead screw 213 can be rotated therewith. In some preferred manners, the fourth motor 221 can drive the second lead screw 213 to perform clockwise or counterclockwise motion; the fourth motor 221 has two motion modes of uniform speed and variable speed. In other modes, a screw rod is not adopted, and a gear and a toothed plate are combined to adjust the horizontal position of the reagent kit 201.
In other preferred modes, instead of the lead screw, as shown in fig. 49-51, a motor 400, a gear assembly (including a third gear 401 and a fourth gear 402), a conveyor belt 403, a sliding block 404 and a limiting device are used, the limiting device is a shell 405 with an opening, the motor 400 is installed inside the shell 405, and the third gear 401 and the fourth gear 402 are also installed inside the shell 405; the motor 400 is connected to a third gear 401, the third gear 401 and a fourth gear 402 are respectively connected to a conveyor belt 403, a slider 404 is connected to the conveyor belt 403, the slider 404 is directly or indirectly connected to the reagent cartridge 200, in this embodiment, as shown in fig. 51, the slider 404 is connected to the tray 202, and the reagent cartridge 200 is mounted inside the tray 202. The motor 400 rotates to drive the third gear 401 and the fourth gear 402 to rotate, the conveyor belt 403 moves, the sliding block 404 moves, the reagent kit 200 can move at the opening, and the length of the opening determines the moving distance of the reagent kit.
In some preferred manners, the fourth motor 221 can be installed and fixed on the bottom plate 222, in some preferred manners, the fourth motor 221 is installed on the first support 220, the first support 220 can be fixed on the bottom plate 222 of the frame module 8, and then the fourth motor 221 can be fixed.
In some preferred manners, the reagent position adjusting device further includes a limiting structure, in some preferred manners, the limiting structure includes a second support 215 and a third support 207, and the second support 215 and the third support 207 can be respectively connected and fixed with the bottom plate 222. In this embodiment, as shown in fig. 24, the hole locations at the bottom of the second support 215 and the third support 207 are aligned with the corresponding hole locations of the bottom plate 222 and tightly attached to the step surface, and screws are screwed into the corresponding hole locations respectively for locking.
In some preferred modes, as shown in fig. 24, a first bearing 216 and a second bearing 214 are connected to the second support for connecting and fixing the second lead screw, the rotating shaft of the motor is connected with a second coupling 219, and the second coupling 219 is connected with the second lead screw 213. In this embodiment, as shown in fig. 24, the fourth motor 221 is installed in the first support 220 to the motor installation surface, and the screw is screwed into the corresponding hole position and locked; one end of the second coupling 219 penetrates through the rotating shaft of the motor 221, and the other end penetrates through the second lead screw 213 to the step surface to be fixedly connected.
In some preferred modes, as shown in fig. 24, the second support 215 is provided with a mounting hole, the first bearing 216 and the second bearing 214 are mounted in the mounting hole, the third support 207 is also provided with a mounting hole, the third bearing 209 is mounted in the mounting hole, one end of the second lead screw 213 is connected with the second bearing 214, and the other end of the second lead screw is connected with the third bearing 209. In some preferred manners, a second screw rod sleeve 212 is connected to the second screw rod 213 at an intermediate position, and when the second screw rod 213 rotates, the second screw rod sleeve 212 can perform a linear motion between the second support 215 and the third support 207. In some preferred manners, the second screw sleeve 212 is connected to the tray 202, the second screw sleeve 212 can support the tray 202 and can drive the tray 202 to move linearly along the screw shaft, and in some preferred manners, as shown in fig. 24, the screw 205 is used to connect and fix the tray 202 on the upper portion of the screw sleeve 211.
In some preferred manners, the second support 215 and the third support 207 are further connected with a first optical axis 210 and a second optical axis 2101, in this embodiment, as shown in fig. 24, a connection hole is formed on the second support 215 and the third support 207, and the first optical axis 210 and the second optical axis 2101 may be connected and fixed on the second support 215 and the third support 207. In some preferred modes, the first optical axis 210 and the second optical axis 2101 are respectively connected with the first optical axis sleeve 211 and the second optical axis sleeve 2102, the first optical axis sleeve 211 and the second optical axis sleeve 2102 are respectively connected with the tray 202, and in some preferred modes, the tray 202 is fixed on the first optical axis sleeve 211 and the second optical axis sleeve 2102 by using screws, so that the weight of a part of the reagent kit 201 can be shared by the second lead screw 213, the reagent kit 201 can be supported together, and the structure is more stable. In some preferred manners, the first optical axis 210 and the second optical axis 2101 are respectively located at two sides of the second lead screw 213. The fourth motor 221 is started, the fourth motor 221 can drive the second coupler 219 to rotate, and the second coupler 219 drives the second lead screw 213 to rotate, so that the second lead screw sleeve 212 and the tray 202 can perform forward or backward linear reciprocating motion, and the position of a reagent in the reagent box 201 can be changed, thereby facilitating detection by a sensor; the second support 215 and the third support 207 at the two ends of the first optical axis 210 are mechanical limits, which can limit the movement range of the lead screw sleeve (at the same time, the number of rotation turns of the motor is defined as a software limit in a system program). In some preferred forms, the fourth motor 221 is a stepping motor, and the second lead screw 213 and the second lead screw housing 212 are ball screws. The stepping motor can realize accurate control according to the constant rotation characteristic of the stepping angle; the ball screw can realize higher displacement precision and transmission efficiency, extremely low shaking coefficient and friction resistance and higher repeated positioning precision during reciprocating movement.
In some preferred modes, as shown in fig. 4, the transmission module 1 comprises a wireless transmitter 104, a mounting bracket 105 and a data transmission device; the data transmission device comprises a quick connector 101 and a wireless transmission circuit board 100, wherein the quick connector 101 is connected with the wireless transmission circuit board 100 through a connecting line, and a data input element 102 and a data output element 103 are arranged on the wireless transmission circuit board 100. As shown in fig. 5, the wireless transmitter 104 is connected to the mounting bracket 105, and the wireless transmitter 104 is mounted on the side of the frame module 8 via the mounting bracket 105 and the set screw 111. As shown in fig. 6, the wireless transmission circuit board 100 is fastened to the sensor pressure plate 135 using the support cylinder 110 and the set screw 111; the quick connect plug 101 may be inserted into a connection port of the sensor pressure plate 135. The data information is transferred to the wireless transmitter 104 through the wireless transmission circuit board 100, the data input element 102, and the data output element 103. The wireless transmitter 104 converts the data into wireless signals through wireless technology, and transmits the wireless signals to the control module 6 according to the requirements of the interaction module 2. The wireless transmitter 104 is also capable of transmitting a wireless signal to an external signal receiving device.
The wireless transmitter 104 in the invention adopts the existing conventional wireless transmitter, and the transmission mode can adopt Bluetooth transmission or wireless SmartAir transmission.
Bluetooth transmission has the following advantages:
a. bluetooth uses the 2.4G ISM frequency band which is universal all over the world and can be used without license in the world; b. the Bluetooth device is micro-modularized; the data transmission between the Bluetooth devices does not need complex setting; d. the data transmission rate is high, and the transmission distance is long; e. has good anti-interference capability.
The Bluetooth transmission can be well used as a wireless transmission link among the sensor module 3, the reagent module 4, the driving module 7 and the control module 6; and the system can be perfectly compatible with a PC (personal computer) end and a client, and is a preferred mode of the invention.
The wireless SmartAir transmission has the following advantages:
a. ultra-high speed b, ultra-low power consumption c, ultra-low delay d, ultra-low cost e, ultra-low radiation.
The wireless SmartAir transmission can be used as a wireless transmission link among the interaction module 2, the driving module 7 and the control module 6.
As shown in fig. 26, the power supply module 5 includes a transformer 5111, an external three-phase outlet 1151, and a power switch 116, and the transformer 5111 is connected to the external three-phase outlet 1151 and the power switch 116 through connection lines, respectively. In some preferred modes, an INPUT + port, an INPUT-port, a ground port, an OUTPUT + port, and an OUTPUT-port are provided inside the transformer 5111; the power switch 116 includes a switch button, and an INPUT + port, an INPUT-port, and a ground port are provided in the external three-phase outlet 1151.
The power supply module is mainly used for continuously converting external voltage into voltage used by the whole device through a transformer 5111, wherein INPUT + and INPUT-are INPUT ends; OUPUT +, OUTPUT-are OUTPUT terminals. Under normal power conditions, power may be manually turned off and on via the power switch 116.
As shown in fig. 27, the control module 6 includes a single chip microcomputer 300, an output terminal 301, an input terminal 302, a wireless transmission element 303, a data input/output serial port 304, and a power supply terminal 305.
As shown in fig. 28, the single chip microcomputer 300 writes in program instructions through the data input/output serial port 304, can read/store system data, and is a central core of the whole device. The power supply module 4 supplies power to the power supply terminal 305, and activates the rest of the components of the control module 6. The wireless transmission element 303 is used for wirelessly receiving/sending signals to the transmission module 1, and the control module 6 is used for transmitting signals to the interaction module 2 and the driving module 7 through the input end 302 and the output end 301 in a wired manner.
As shown in fig. 28, the driving module 7 includes an output terminal 310 and an input terminal 311. As shown in fig. 28, the signal of the control module 6 can be transmitted to the driving module 7 through the input terminal 311, and then transmitted to the sensor module 3 and the reagent module 4 through the output terminal 310.
In some preferred modes, as shown in fig. 7, the interactive module 2 includes a touch screen 115, and the lower end of the touch screen 115 is provided with a USB data port 112, a power supply wire 113, and a control module connecting wire 114. The control module 6 and the interaction module 2 are connected by a wire (i.e., a control module connection wire 114).
As shown in fig. 8, after the sensor module 3 and the reagent module 4 are respectively placed with corresponding sensors and reagents, the reagent sensor 2013 and/or the reagent induction ring 2012 transmit the collected reagent information to the transmission module 1, the sensor collects sensor placement position signals and can transmit the signals to the transmission module 1, the sensors and the reagents generate chemical reaction identification valid/invalid signals and then transmit the signals to the transmission module 1, and the wireless transmission circuit board 100 in the transmission module 1 receives the signals and can transmit the signals to the control module 6.
When the control module 6 successfully identifies the signal, the data is processed and then transmitted to the interaction module 2 and the driving module 7 through wires. At this time, the interactive module 2 displays a program interface to show that the next step operation can be performed.
When the control module 6 recognizes incorrectly, the interactive module 2 displays that the reagent and/or the sensor is placed incorrectly or the placed object is incorrect, and the touch screen 115 may be a voice interactive type, a key digital display interactive type or a touch panel interactive type.
The research and development personnel can complete each instruction by talking with the voice interactive touch screen 115. The identity of the user can be recognized through voice, and if the user is not a research and development worker, the touch screen system sends out an alarm sound and closes the system; research personnel interact with the touch screen system through the input of the key digital display interactive touch screen 115, and characters and graphs can be displayed on the screen of the touch screen 115; the on-screen haptic feedback system can drive various connected devices when a developer touches graphical buttons on the screen through the touch panel interactive touch screen 115.
Fig. 9 is a circuit connection diagram of the interactive module 2 and other modules, and it can be seen that the motors (including the first motor 121, the second motor 140, the third motor 206, and the fourth motor 221) are connected to the driving module 7 and can provide power, the driving module 7 is connected to the control module 6, the control module 6 is connected to the touch screen 115, and the control module 6 is further connected to the power supply module 5.
In the control module 6, the single chip microcomputer 300 is a core control component, is connected with a touch display screen through a serial port, communicates through the serial port, performs corresponding operation according to touch input of a user, transmits current information collected by a sensor at present through a Bluetooth module and an upper computer, a power box is a power supply module, performs AC-DC conversion to supply power to the whole control system, the single chip microcomputer 300 performs stroke control on a stepping motor through a stepping motor driver to enable the sensor to reach a set kit position, and a stroke switch is responsible for position determination. Each stepper motor is provided with two travel switches defining a starting and operating position. In the embodiment, the adopted single chip microcomputer and the adopted stepping motor are both in the prior art, and the structure, the principle and the connection relation of the single chip microcomputer and the stepping motor are not improved.
A method for detecting sensor performance, which can adopt the multi-channel detection device, comprises the following steps:
(1) placing the sensor in the sensor placement board 134;
(2) reading sensor data, wherein the sensor data comprises the type, the number and the like of the sensors;
(3) selecting sensor detection parameters, wherein the sensor detection parameters comprise sensitivity, service life, mechanical property, repeatability precision, corrosion resistance and the like;
(4) putting corresponding detection reagents;
(5) selecting a detection scheme, wherein the detection scheme comprises static detection, vibration detection, vortex detection, reciprocating detection and composite detection;
(6) carrying out real-time detection;
(7) the real-time detection result is displayed, the detection result can be in a character table or a curve graph form, and as shown in fig. 34, the detection result can be derived. In some preferred modes, the detection result can be transmitted to the PC terminal or the mobile terminal through bluetooth or WiFi.
In some preferred manners, in step (1), after the sensor is placed on the sensor placement board 134, the sensor 1331 checks the sensor placement position information, and transmits the data information to the transmission module 1, the wireless transmission circuit board 100 in the transmission module 1 receives the signal and can send the signal to the control module 6 (or the sensor 1331 can directly and wirelessly transmit the collected sensor placement position information to the control module 6), the control module 6 analyzes and judges whether the sensor placement position is correct, and if the sensor placement position is correct, the data is processed and then transmitted to the interaction module 2 and the driving module 7 through a wire. At this time, the interactive module 2 displays a program interface to show that detection can be carried out; if the data is incorrect, the data is processed and then transmitted to the interactive module 2 through a wire, at this time, the interactive module 2 displays that the reagent and/or the sensor is placed incorrectly or the placed object is wrong, and the like, and the touch screen 115 can be a voice interactive type, a key digital display interactive type or a touch panel interactive type.
In some preferred modes, the specific process of step (2) is as follows: the single chip microcomputer 300 in the control module 6 reads the sensor data information and can transmit the data information to the interaction module 2, and the interaction module 2 displays the type of the sensors and the number of the sensors, as shown in fig. 34.
In some preferred manners, in step (3), after the detection scheme is selected, the interaction module 2 feeds back the information to the control module 6, the control module 6 analyzes and processes the information and then transmits the information to the interaction module 2, and the interaction module 2 displays an interface of the next step: prompting the placement of reagents into the kit.
In some preferred manners, in step (4), after the corresponding detection reagent is put in, the reagent sensor 2013 and/or the reagent induction ring 2012 can transmit the collected reagent information (including the amount of the reagent and whether the correct reagent is put in) to the transmission module 1, the wireless transmission circuit board 100 in the transmission module 1 receives the signal and can transmit the signal to the control module 6, the single-chip microcomputer 300 of the control module 6 analyzes and judges whether the received reagent information matches with the stored reagent information in advance (different sensor detection parameters, different reagents need to be used for inspection, and the information is stored in the single-chip microcomputer 300 in advance), and if the received reagent information matches with the stored reagent information, the single-chip microcomputer 300 processes the data and transmits the processed data to the interaction module 2; at the moment, the interactive module 2 displays an operation interface of the next step; if the reagent information is not matched, the single chip microcomputer 300 processes the data and transmits the processed data to the interaction module 2; at this time, the interactive module 2 displays that the amount of reagent is insufficient and/or that the reagent is wrong, etc.
In some preferred manners, in step (5), after the detection scheme is selected, the interaction module 2 transmits the information to the control module 6, and the control module 6 analyzes and processes the information and transmits the information to the driving module 7. As shown in fig. 31, the parameters that can be used for detection in the stationary detection are sensitivity and corrosion resistance, and the parameters that can be used for detection in the vibration detection are sensitivity and service life; parameters which can be used for detection in vortex detection are mechanical property and repetition precision, and parameters which can be used for detection in reciprocating detection are sensitivity and repetition precision; the composite detection can be used for detecting parameters such as sensitivity, repeatability precision, service life, mechanical property and corrosion resistance; the corresponding detection scheme needs to be selected according to the detection parameters selected previously.
In some preferred modes, in step (6), after the driving module receives the data information, the driving motor works to perform the detection operation. As shown in fig. 44, the specific process of performing the still detection is as follows: the driving module 7 transmits information to the sensor module 3 and the reagent module 4, the second motor 140 in the sensor module 3 works to drive the first synchronous wheel 139, the synchronous belt 138 and the second synchronous wheel 1391 to move, the sensor pressing plate 135 rotates, the sensor placing plate 134 rotates, an included angle between the sensor pressing plate 135 and the sensor placing plate 134 is gradually reduced, and finally the sensor pressing plate 135 compresses and fixes the sensor placing plate 134; according to the position of the sensor, the fourth motor 221 of the reagent module 4 works to drive the second screw rod 213 to rotate, so that the reagent kit moves backward or forward to the working position (in specific implementation, the reagent kit 201 moves to the lower side of the sensor, so that the sensor can be conveniently inserted into the reagent for detection). The first motor 121 in the sensor module is operated, the first lead screw 124 is rotated, the first lead screw sleeve 127 and the mounting plate 128 move downwards, and the sensor moves downwards along with the first lead screw sleeve until the sensor is immersed in the reagent for detection.
In some preferred manners, in step (6), as shown in fig. 46, the specific process of performing vibration detection is as follows: on a stationary basis, the sensor reciprocates up and down in the reagent and/or the sensor reciprocates forward and backward in the reagent. In some preferred manners, the first motor 121 rotates counterclockwise (or rotates clockwise) to drive the first lead screw 124 to rotate, the first lead screw sleeve 127 and the mounting plate 128 move downward (or move upward), the sensor moves downward (or move upward) in the reagent, and the sensor completes detection during the upward and downward reciprocating movement, so that reciprocating detection results of the sensor at different depths of the reagent can be obtained. In some preferred manners, the fourth motor 221 rotates counterclockwise (or rotates clockwise) to drive the second screw 213 to rotate, the second screw sleeve 212 and the reagent kit move forward (or move backward), the reagent moves forward (or move backward) along with the reagent kit, and the sensor completes detection during the forward and backward reciprocating movement of the reagent, so that reciprocating detection results of the sensor at different horizontal positions of the reagent can be obtained. In some preferred modes, the sensor reciprocates up and down in the reagent, while the sensor reciprocates forward and backward in the reagent, during which the sensor performs detection.
In some preferred modes, in step (6), as shown in fig. 47, the specific process of performing vortex detection is as follows: on the basis of static detection, a third motor 206 in the reagent module 4 works (clockwise or anticlockwise) to drive a second gear 204 to work, the first gear 203 rotates along with the second gear, the reagent kit 201 connected with the first gear 203 rotates, reagents are uniformly mixed, and the sensor detects in the state.
In some preferred manners, in step (6), as shown in fig. 46, the specific process of performing the reciprocating detection coincides with the process of vibration detection, but the motion amplitude of the vibration detection is smaller than that of the reciprocating detection, and the frequency of the vibration detection is lower than that of the reciprocating detection. The preferred amplitude of motion for vibration detection is +/-0.5mm, with a preferred frequency of 0.2 s; the preferred amplitude of motion for the reciprocating detection is +/-2mm, with a preferred frequency of 1 s.
In some preferred modes, in step (6), as shown in fig. 48, the specific process of performing the composite detection is as follows: there are both reciprocating and vortex detection. The reciprocating detection is the same as the reciprocating detection step, and the vortex detection is the same as the vortex detection step.
Some steps in the detection method described above may be performed in the interactive module 2. The operational interfaces of the interactive module 2 are shown in fig. 33-34.
The device of the invention can be used for detecting some performance parameters of the sensor, and can also be used for detecting the reagent to obtain related components of the reagent. As shown in fig. 32, when detecting a reagent, (1) a test reagent to be detected is first put in, the reagent sensor 2013 and/or the reagent induction ring 2012 can transmit collected reagent information (including the amount of the reagent) to the transmission module 1, the wireless transmission circuit board 100 in the transmission module 1 receives a signal and can transmit the signal to the control module 6, (2) the single chip microcomputer 300 of the control module 6 analyzes and judges whether the received reagent information matches with the pre-stored reagent information (whether the reagent amount is enough for detection), and if so, the single chip microcomputer 300 processes the data and transmits the processed data to the interaction module 2; at this time, the interactive module 2 displays the volume, number and number of the reagent; if the reagent information is not matched, the single chip microcomputer 300 processes the data and transmits the processed data to the interaction module 2; at this point the interactive module 2 displays that the amount of reagent is insufficient, etc. (3) Selecting components to be detected, wherein the components to be detected comprise saccharides, enzymes, lipids, minerals, metals and the like; for example, the saccharide in the detection reagent can be selected for reagent No. 2, and the enzyme in the detection reagent can be selected for reagent No. 8. (4) Putting the corresponding sensors, reading the types, the number, the placement positions and the like of the sensors by the sensor inductor 1331, transmitting the information to the transmission module 1, receiving signals by the wireless transmission circuit board 100 in the transmission module 1 and sending the signals to the control module 6, analyzing and judging whether the received sensor information is matched with the sensor information stored in advance by the singlechip 300 of the control module 6, and giving a prompt by the interaction module if the received sensor information is not matched with the sensor information stored in advance; if the matching is carried out, the next step is carried out; (5) selecting a detection scheme, wherein the detection scheme comprises static detection, vibration detection, vortex detection, reciprocating detection, composite detection and the like; (6) carrying out real-time detection, and (7) displaying a real-time detection result, wherein the detection result can be in a form of a character table and a curve graph, and can be transmitted to a PC (personal computer) end or a mobile end through Bluetooth and WiFi (wireless fidelity).
Example 2
In this embodiment, the fixing mechanism includes a sensor placement plate 134 (the fixing mechanism does not include a sensor pressure plate), and the sensor placement plate 134 is fixedly mounted or indirectly connected to the mounting plate 128; the sensor placement board 134 can be used to place and fix the sensor 133.
The surface of the sensor placement board 134 is further provided with a slot 1329, the slot 1329 is convenient for placing the sensor and can fix the sensor, so that the sensor is in a certain fixed state, and the sensor is prevented from inclining or separating from the sensor placement board 134. In some preferred forms, the slot 1329 is shaped to match the shape of the sensor, and in some preferred forms, the open end of the slot 1329 is provided with a positioning surface 1330, the positioning surface 1330 being capable of fixing the upper segment 1322 of the sensor when the sensor is placed in the slot 1329.
In some preferred modes, a sensor inductor is further arranged inside the slot of the sensor placing board, and the sensor inductor can read information such as the type, the number, the placing position and a sensor detection signal of the sensor and transmit the detected signal to the control module in a wired or wireless mode.
In some preferred manners, after the sensors are placed in the positioning slots 1329, the sensor sensors contact the contacts on the sensors, and the sensor sensors can receive signals related to the sensors, such as the model, number, placement position, sensor detection signals and the like.
The sensor inductor can adopt the existing sensor inductor in the prior art, and the structure and the working principle of the sensor inductor are not improved.
Other embodiments in this embodiment may be the same as embodiment 1.
It is to be understood that the described embodiments are merely a few embodiments of the invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

Claims (10)

1. A method of detecting sensor performance, comprising the steps of:
(1) placing the sensor in a sensor placing plate;
(2) reading sensor data;
(3) the sensor is selected to detect the parameter(s),
(4) putting corresponding detection reagents;
(5) selecting a detection scheme, wherein the detection scheme comprises static detection, vibration detection, vortex detection, reciprocating detection and composite detection;
(6) carrying out real-time detection;
(7) and displaying the real-time detection result.
2. The method for detecting sensor performance as claimed in claim 1, wherein in the step (2), the sensor data includes the type and number of the sensors.
3. The method for detecting the performance of the sensor according to claim 1, wherein in the step (3), the detection parameters of the sensor comprise sensitivity, service life, mechanical property, repeatability precision and corrosion resistance.
4. The method for detecting the performance of the sensor according to claim 1, wherein in the step (6), the static detection is performed by the following specific processes: the second motor works to drive the first synchronous wheel, the synchronous belt and the second synchronous wheel to move, the sensor pressing plate rotates, the sensor placing plate rotates, the included angle between the sensor pressing plate and the sensor placing plate is reduced, and finally the sensor pressing plate fixes the sensor; according to the position of the sensor, the fourth motor works to drive the second screw rod to rotate, so that the reagent box moves backwards or forwards to a working position; the first motor works to drive the first screw rod to rotate, the first screw rod sleeve and the mounting plate move downwards, and the sensor moves downwards along with the first screw rod sleeve until the sensor is immersed in a reagent to perform detection.
5. The method for detecting the performance of the sensor according to claim 4, wherein in the step (6), the vibration detection is performed by: on the basis of static detection, the sensor reciprocates upwards and downwards in the reagent; or/and the sensor reciprocates back and forth in the reagent.
6. The method for detecting the performance of the sensor according to claim 5, wherein in the step (6), the specific process of the upward or downward movement of the sensor in the reagent is as follows: the first motor rotates to drive the first screw rod to rotate, the first screw rod sleeve and the mounting plate move downwards or upwards, the sensor moves downwards or upwards in the reagent along with the mounting plate, and the sensor completes detection in the process of moving upwards or downwards.
7. The method for detecting the performance of the sensor according to claim 5, wherein in the step (6), the forward or backward movement of the sensor in the reagent is carried out by the following specific processes: the fourth motor rotates to drive the second screw rod to rotate, the second screw rod sleeve and the reagent box move forwards or backwards, the reagent moves forwards or backwards along with the reagent box, and the sensor completes detection in the process that the reagent moves forwards or backwards.
8. The method for detecting the performance of the sensor according to claim 4, wherein in the step (6), the vortex detection is carried out by the specific processes of: on the basis of static detection, the third motor works to drive the second gear to rotate, the first gear rotates along with the second gear, the reagent kit connected with the first gear rotates, and the sensor detects in a vortex state.
9. The method for detecting the performance of a sensor according to claim 4, wherein in the step (6), the process of performing the reciprocating detection is the same as the process of performing the vibration detection, but the motion amplitude of the vibration detection is smaller than that of the reciprocating detection, and the frequency of the vibration detection is lower than that of the reciprocating detection.
10. The method for detecting the performance of the sensor according to claim 4, wherein in the step (6), the composite detection is carried out by the following specific processes: on the basis of static detection, reciprocating detection and vortex detection are carried out simultaneously.
CN202010856740.0A 2020-08-24 2020-08-24 Method for detecting performance of sensor Pending CN112450923A (en)

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Citations (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1473270A (en) * 2001-08-09 2004-02-04 ���µ�����ҵ��ʽ���� Biosensors and measurement method
WO2007084130A1 (en) * 2006-01-17 2007-07-26 Dexcom, Inc. Low oxygen in vivo analyte sensor
US20100169035A1 (en) * 2008-12-29 2010-07-01 Medtronic Minimed, Inc. Methods and systems for observing sensor parameters
KR20120088349A (en) * 2011-01-31 2012-08-08 주식회사 엘지생명과학 Diagnostic Equipment for signal detection of specimen using magnetic resistance sensor
CN103995139A (en) * 2014-05-30 2014-08-20 浙江大学 In vitro performance evaluating system of continuous blood sugar monitoring sensor
CN104470431A (en) * 2012-05-25 2015-03-25 美敦力迷你迈德公司 Foldover sensors and methods for making and using them
CN204514941U (en) * 2015-03-23 2015-07-29 上海蓝怡科技有限公司 A kind of evenly mixing device and automatic detection system
US20190077024A1 (en) * 2015-10-13 2019-03-14 Sensapex Oy Integrated measurement and micromechanical positioning apparatus for real-time test control
CN109490806A (en) * 2018-11-27 2019-03-19 南方电网科学研究院有限责任公司 A kind of detection method of sensor, system, device and readable storage medium storing program for executing
KR20200025610A (en) * 2018-08-31 2020-03-10 주식회사 리얼게인 Integrated apparatus for diagnosing sensors
CN210664984U (en) * 2019-11-29 2020-06-02 韶关学院 Vortex generation and detection experimental device
CN210719232U (en) * 2019-11-22 2020-06-09 深圳市第二人民医院 Biosensor performance detection device

Patent Citations (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1473270A (en) * 2001-08-09 2004-02-04 ���µ�����ҵ��ʽ���� Biosensors and measurement method
WO2007084130A1 (en) * 2006-01-17 2007-07-26 Dexcom, Inc. Low oxygen in vivo analyte sensor
US20100169035A1 (en) * 2008-12-29 2010-07-01 Medtronic Minimed, Inc. Methods and systems for observing sensor parameters
KR20120088349A (en) * 2011-01-31 2012-08-08 주식회사 엘지생명과학 Diagnostic Equipment for signal detection of specimen using magnetic resistance sensor
CN104470431A (en) * 2012-05-25 2015-03-25 美敦力迷你迈德公司 Foldover sensors and methods for making and using them
CN103995139A (en) * 2014-05-30 2014-08-20 浙江大学 In vitro performance evaluating system of continuous blood sugar monitoring sensor
CN204514941U (en) * 2015-03-23 2015-07-29 上海蓝怡科技有限公司 A kind of evenly mixing device and automatic detection system
US20190077024A1 (en) * 2015-10-13 2019-03-14 Sensapex Oy Integrated measurement and micromechanical positioning apparatus for real-time test control
KR20200025610A (en) * 2018-08-31 2020-03-10 주식회사 리얼게인 Integrated apparatus for diagnosing sensors
CN109490806A (en) * 2018-11-27 2019-03-19 南方电网科学研究院有限责任公司 A kind of detection method of sensor, system, device and readable storage medium storing program for executing
CN210719232U (en) * 2019-11-22 2020-06-09 深圳市第二人民医院 Biosensor performance detection device
CN210664984U (en) * 2019-11-29 2020-06-02 韶关学院 Vortex generation and detection experimental device

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