CN112402740A

CN112402740A - Injection pen and injection device

Info

Publication number: CN112402740A
Application number: CN201910772035.XA
Authority: CN
Inventors: 杨云龙; 张春; 车宇峰; 万亮; 孙筱婷; 孙琪; 江晨宇; 俞文; 叶颖
Original assignee: Fudan University
Current assignee: Fudan University
Priority date: 2019-08-21
Filing date: 2019-08-21
Publication date: 2021-02-26

Abstract

The invention belongs to the technical field of medical equipment, and relates to an injection pen and an injection device; the injection pen comprises an injection pen barrel, a medicine bin arranged inside the injection pen barrel, a capacitor and a medicine pushing structure. The medicine bin is filled with medicines in advance, and the medicines are selected according to a preset dose. The medicine pushing structure is movably connected with the medicine bin, and at least part of the medicine pushing structure is positioned in the medicine bin. The capacitor and the medicine pushing structure are arranged at intervals, and the capacitor is used for exploding to generate high-pressure driving gas when the capacitor is charged to enable the charging amount of the capacitor to exceed a preset threshold value. When the high-pressure driving gas is generated, the medicine pushing structure pushes the medicine in the medicine bin under the driving of the high-pressure driving gas so that the medicine can be injected to the subcutaneous tissue of a user in a liquid flow mode. The injection pen has the advantages of small volume, portability and convenience in operation.

Description

Injection pen and injection device

Technical Field

The invention belongs to the technical field of medical equipment, and particularly relates to an injection pen and an injection device.

Background

With the rapid development of modern medical science and technology, the treatment problem of many diseases is solved. However, there are diseases that require multiple or complex repeated dosing regimens over an extended period of time to provide for sustained treatment or control of the condition. For example: patients with diabetes need to use insulin for a long time, and patients with moderate to severe chronic pain need to use fentanyl for a long time; at present, the treatment of the diseases needs to be performed by a subcutaneous injection way to exert the efficacy of the medicine, and the existing medicine injector has larger volume and is not convenient to carry and operate when in use.

Based on the current state of the art, the inventor of the present application intends to provide an injection pen and an injection device that have a small volume, are convenient to carry, and are convenient to operate.

Disclosure of Invention

The present invention is directed to providing an injection pen and an injection device, which have a small volume, are easy to carry, and are easy to operate.

The present application provides an injection pen, comprising: the injection pen container, the medicine bin arranged in the injection pen container, the capacitor and the medicine pushing structure; the medicine bin is internally pre-filled with medicines, and the medicines are selected according to a preset dose; the medicine pushing structure is movably connected with the medicine bin, and at least part of the medicine pushing structure is positioned in the medicine bin; the capacitor and the medicine pushing structure are arranged at intervals, and the capacitor is used for exploding to generate high-pressure driving gas when the capacitor is charged to enable the charging amount of the capacitor to exceed a preset threshold value;

when the high-pressure driving gas is generated, the medicine pushing structure pushes the medicine in the medicine bin under the driving of the high-pressure driving gas so that the medicine can be injected to the subcutaneous tissue of a user in a liquid flow mode.

In an embodiment, the medicine pushing structure includes a liquid pushing plate, a piston shaft and a piston which are connected in sequence, the piston is arranged in the medicine bin, one end of the piston shaft can extend into the medicine bin and is connected with the piston, the other end of the piston shaft is connected with the liquid pushing plate, and the liquid pushing plate is used for pushing the piston to move to discharge the medicine under the driving of the high-pressure driving gas.

In one embodiment, the injection pen further comprises an injection tube, the injection tube is arranged at one end of the medicine bin, which is far away from the piston, and communicated with the medicine bin, and the outer diameter of the injection tube is smaller than that of the medicine bin.

In one embodiment, a protective sleeve is arranged between the injection tube and the wall of the injection pen barrel.

In an embodiment, the injection pen further comprises a power supply and a power supply controller, wherein the power supply controller is used for controlling the power supply to supply power to the capacitor.

In one embodiment, the injection pen barrel is provided with a first end and a second end opposite to the first end, the first end is provided with a blocking piece, and the blocking piece is arranged corresponding to the position of the injection tube and is movably connected with the first end.

In an embodiment, the second end is provided with a trigger, and the trigger is electrically connected with the power supply controller to trigger the power supply controller to control the power supply to supply power to the capacitor.

In one embodiment, the injection pen further comprises a pen cap, and the pen cap is detachably arranged at the front end of the pen container of the injection pen.

In one embodiment, the outer surface of the pen container of the injection pen is further provided with anti-skid grains.

The application still provides an injection apparatus, injection apparatus put the frame including the injection pen with the injection pen, the power is located the injection pen is put on the frame, the injection pen is put the frame and is used for the holding the injection pen and do the injection pen power supply.

Compared with the prior art, the injection pen in the application explodes by charging the capacitor to generate high-pressure driving gas and enables the high-pressure driving gas to serve as power to push the medicine pushing structure to move, so that the medicine in the medicine pushing structure pushing the medicine bin is discharged from the medicine bin quickly, penetrates through epidermal cells in the form of a liquid needle instantly and permeates into subcutaneous tissues to complete injection, and pain of a user is reduced. Simultaneously, adopt the condenser to come to promote the medicine as power and discharge in order to accomplish the injection, on the one hand because of the condenser is economical and practical to can reduce the cost of injection pen, improve the production efficiency of injection pen, on the other hand is because of the condenser volume is less, thereby can reduce the volume of injection pen, makes the syringe portable and easily operation, has increased the convenience of injection.

Drawings

In order to more clearly illustrate the technical solution of the embodiment of the present invention, the drawings used in the description of the embodiment will be briefly introduced below.

FIG. 1 is a schematic structural diagram of one embodiment of an injection pen provided herein;

FIG. 2 is a schematic cross-sectional view of the injection pen shown in FIG. 1 along line I-I;

FIG. 3 is a schematic view of the cartridge and pusher structure of FIG. 2;

FIG. 4 is a schematic diagram of an electrical circuit configuration of an injection pen provided herein;

FIG. 5 is a schematic structural diagram of another embodiment of an injection pen provided herein;

fig. 6 is a schematic view of an injection device provided herein.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are some, not all, embodiments of the present invention. Reference herein to "an embodiment" means that a particular feature, structure, or characteristic described in connection with the embodiment can be included in at least one embodiment of the invention. The appearances of the phrase in various places in the specification are not necessarily all referring to the same embodiment, nor are separate or alternative embodiments mutually exclusive of other embodiments. It is explicitly and implicitly understood by one skilled in the art that the embodiments described herein can be combined with other embodiments.

Referring to fig. 1 to 3 together, fig. 1 is a schematic structural diagram of an embodiment of an injection pen provided by the present application; FIG. 2 is a schematic cross-sectional view of the injection pen shown in FIG. 1 along line I-I; fig. 3 is a schematic structural view of the medicine bin and the medicine pushing structure in fig. 2.

The injection pen 100 comprises an injection pen barrel 10, a medicine bin 20 arranged inside the injection pen barrel 10, a capacitor 30 and a medicine pushing structure 40. The medicine bin 20 is filled with medicines 201 in advance, and the medicines 201 are selected according to a preset dosage. The medicine pushing structure 40 is movably connected with the medicine bin 20, and at least part of the medicine pushing structure 40 is positioned in the medicine bin 20. The capacitor 30 is spaced apart from the medicine pushing structure 40, and the capacitor 30 is used for generating high-pressure driving gas by explosion when the capacitor is charged to enable the charging amount of the capacitor to exceed a preset threshold value. When the high-pressure driving gas is generated, the medicine pushing structure 40 pushes the medicine 201 in the medicine bin 20 under the driving of the high-pressure driving gas, so that the medicine 201 can be injected to the subcutaneous tissue of the user in a liquid flow manner.

The injection pen 100 in this application is through making the condenser 30 explode to produce high pressure drive gas, and make high pressure drive gas move in order to promote the medicine pushing structure 40 as power, thereby make the medicine 201 that pushes away in the medicine storehouse 20 of medicine pushing structure 40 promote the medicine storehouse 20 discharge from the medicine storehouse 20 fast, pass the epidermal cell in the twinkling of an eye with the form of "liquid needle", the infiltration is into subcutaneous tissue, accomplishes the injection, thereby has reduced user's painful sense. Simultaneously, adopt the condenser 30 to come to promote medicine 201 as power and discharge in order to accomplish the injection, on the one hand because of condenser 30 is economical and practical to can reduce injection pen 100's cost, improve injection pen 100's production efficiency, on the other hand because of condenser 30 is small, thereby can reduce injection pen 100's volume, make the syringe portable and easy to operate, increased the convenience of injection.

The injection pen barrel 10 has a first end 101 and a second end 102 disposed opposite the first end 101, the first end 101 being an end relatively closer to an injection site, and the second end 102 being an end relatively farther from the injection site. It can be understood that the pen container 10 of the injection pen in the present application is similar to a ball-point pen in appearance, and has a structure in which the first end 101 is small and the second end 102 is large, so that the pen container can be conveniently carried due to its small size, and can be combined into various injection scenes, thereby enabling a user to more easily operate and inject the medicine 201, reducing the number of times of going to a hospital, and increasing the convenience of injection.

Further, in order to ensure the smooth injection of the medicine 201, the outer surface of the injection pen barrel 10 is further provided with anti-slip lines 103, and the friction force between the user and the injection pen 100 is increased due to the arrangement of the anti-slip lines 103, so that the user can more stably hold the injection pen 100 for injection, and the injection pen 100 is prevented from falling off due to the fact that the hands slip, and the injection process is prevented from being influenced.

In this embodiment, the cartridge 20 is cylindrical to fit the cylindrical shape of the injection pen 100, thereby reducing the difficulty in manufacturing and further improving the production efficiency. Meanwhile, the medicine bin 20 may be made of a medical polymer material meeting the injection requirement to accommodate a preset dose of the medicine 201 to be injected. The drug 201 can be, but is not limited to, a small peptide or a small molecule drug, the small titanium can be insulin or the like, and the small molecule drug 201 can be a targeting drug, a chemotherapeutic drug, nitroglycerin, a hormone drug 201, fentanyl or the like. In this embodiment, the drug 201 is described by taking insulin as an example.

Further, the capacitor 30 may be, but not limited to, a polyethylene capacitor, a dacron capacitor, a ceramic capacitor, a mica capacitor, a monolithic capacitor, an electrolytic capacitor, etc. Among them, the tantalum capacitor in the electrolytic capacitor has a small volume and can reach a larger capacitance, so that the electrolytic capacitor has a very high working electric field intensity in a unit volume, namely, a very high specific capacity, and is particularly suitable for miniaturization.

Further, the tantalum capacitor includes a tantalum polymer capacitor and a tantalum manganese dioxide capacitor. In this embodiment, the explosion principle of the capacitor 30 will be described by taking tantalum manganese dioxide capacitor as an example, because the capacitor 30 needs to explode.

When the tantalum manganese dioxide capacitor meets the condition that the polarity is reversed and large current is suddenly generated, the cathode manganese dioxide releases a large amount of oxygen due to rapid increase of heat, and the oxygen meets the anode tantalum through cracks or gaps of the medium tantalum pentoxide, so that reaction is generated and explosion is caused. For example, when the polarity of the tantalum-manganese dioxide is reversed and 2 times the rated voltage and 20 amperes (a) of current are applied, the tantalum-manganese dioxide capacitor rapidly explodes and generates high-pressure driving gas.

Further, the pressure generated by explosion will change according to the capacitance of tantalum manganese dioxide capacitor. That is, the capacitance value of each tantalum-manganese dioxide capacitor corresponds to a pressure value at which an explosion generates pressure. For example, the tantalum-manganese dioxide capacitor may be a TAJ series patch tantalum capacitor, and the higher the capacitance value of the TAJ series tantalum capacitor is, the larger the pressure value generated by explosion is, that is, the greater the propelling force for pushing the drug 201 in the drug container 20 is, so that the faster the drug 201 in the drug container 20 is pushed to be injected into the subcutaneous tissue of the human body. Preferably, the tantalum manganese dioxide capacitor may be a type C of TAJ series, having a gauge size of about 6.0 mm x 3.2 mm x 2.5 mm (length x width x thickness), a rated voltage of 10V (volts), and a capacitance of 47UF (microfarads).

It can be understood that, since the capacitor 30 explodes, fragments generated by the explosion of the capacitor 30 are generated inside the injection pen 100 after the explosion, and in order to avoid the contamination of the medicine 201, the medicine bin 20 cannot be detached from the injection pen 100 to replace the new medicine bin 20, so that the purpose of using the injection pen 100 once is achieved, the possibility of secondary use is avoided, and the injection pen is safe and reliable. It should be noted that the higher the capacitance value of the capacitor, the greater the pressure generated by explosion, and the greater the propelling force for pushing the medicine 201 in the medicine bin 20 can be combined into various capacitors in which explosion can occur.

Compared with the conventional injection pen which adopts an air pump, an air bag or a complex spring propelling structure as a power source for propelling the medicine 201 to be injected, the injection pen 100 of the present application adopts the capacitor 30 and explodes the capacitor to generate pressure, the high-pressure driving gas generated by the explosion of the capacitor 30 is enough to propel the medicine pushing structure 40 to gradually discharge the medicine 201 from the medicine bin 20, so as to ensure the fluency and stability of the movement of the medicine pushing structure 40, and the capacitor 30 is adopted as the power source of the injection pen 100, the price is ten times lower than that of the traditional power source, and the capacitor models on the market are more common and more widely applied, it can be understood that more types of capacitors also means more changes of capacitance values of the capacitors, that is, the adjustable range of the pressure generated by explosion is more detailed and specific. On the other hand, the capacitor 30 is used as a power source, and the volume occupied by the capacitor 30 is small, so that the volume of the injection pen 100 is optimized, the volume of the injection pen 100 using the capacitor 30 can be reduced by at least half to two thirds compared with the volume of the existing injection pen, and the portability is enhanced.

Further, the medicine pushing structure 40 includes a liquid pushing plate 41, a piston shaft 42 and a piston 43 which are connected in sequence, the piston 43 is arranged in the medicine bin 20, one end of the piston shaft 42 can extend into the medicine bin 20 and is connected with the piston 43, the other end of the piston shaft 42 is connected with the liquid pushing plate 41, and the liquid pushing plate 41 is used for pushing the piston 43 to move to discharge the medicine 201 under the driving of the high-pressure driving gas.

Specifically, the piston 43 has a cross-sectional diameter substantially the same as the inner cross-sectional diameter of the cartridge 20, so as to ensure that the medicine 201 in the cartridge 20 does not overflow to the end of the cartridge 20 located at the piston 43 through the gap between the piston 43 and the cartridge wall, thereby enabling the medicine 201 to be sufficiently injected and ensuring the utilization rate of the medicine 201.

Further, the injection pen 100 further comprises an injection tube 50, the injection tube 50 is disposed at one end of the medicine bin 20 away from the piston 43 and is communicated with the medicine bin 20, and the outer diameter of the injection tube 50 is smaller than the outer diameter of the medicine bin 20, so that the diameter of the injection tube 50 is smaller, thereby satisfying the principle of high-pressure air jet injection, so that the medicine 201 in the medicine bin 20 can rapidly pass through the injection tube 50 under the pushing of the medicine pushing structure 40, and the injection is ensured to be ejected in a form of a liquid needle. The first end 101 of the injection pen barrel 10 is provided with an exit port 103, and the exit port 103 is aligned with the injection tube 50 to guide the medicine 201 to exit to the injection site of the user.

Furthermore, a protective sleeve 60 is arranged between the injection tube 50 and the wall of the injection pen container 10. The arrangement of the protective sleeve 60 enhances the stability and reliability of the injection tube 50, so that the injection tube 50 is not easily deformed under the driving action of the high-pressure driving gas, and the medicine 201 can be smoothly ejected from the injection tube 50 through the exit port 103, thereby effectively reducing the risk of unsuccessful injection caused by the deviation of the injection tube 50.

Specifically, after the high-pressure driving gas is generated, the liquid pushing plate 41 impacts the piston shaft 42 at a fast speed under the driving action of the high-pressure driving gas, the piston shaft 42 pushes the piston 43 at a fast speed after being impacted, and then pushes the medicine 201 located in the medicine bin 20 to move towards the injection tube 50, the medicine 201 forms a liquid medicine flow jetted at a high speed under the pushing action of the piston 43, and then the liquid medicine flow passes through the injection tube 50 and the exit port 103 in sequence and then exits, so that the medicine 201 can be injected into the subcutaneous tissue of the user in a liquid flow manner.

It can be understood that the injection pen 100 is a needle-free injection pen, the injection pen 100 has a small and exquisite structure, is convenient to operate, does not need a needle tube to be inserted into the skin, does not cause pollution, and is more efficient to use, and meanwhile, as the medicine 201 is injected into the subcutaneous tissue at a high speed, the medicine 201 is in a dispersed and distributed state in the subcutaneous tissue, the medicine 201 has a faster onset time and a higher absorption rate. For example, the injection pen 100 can be used for injecting insulin, so that the insulin can be rapidly dispersed in subcutaneous tissues and can be rapidly absorbed by a human body conveniently, the blood sugar of a diabetic patient can be more accurately controlled, meanwhile, the injection pen 100 is not provided with a needle head, pain caused to the user is extremely weak, the experience degree of the diabetic patient is improved, and the pain of the diabetic patient is further reduced.

Further, the drugs 201 stored in the drug storage 20 can also be packaged into a cylindrical drug package by a polymer material, and the cylindrical drug package contains a preset dosage of the drugs 201, and specifically, the polymer material can be polyvinyl chloride or polypropylene. The columnar charge is ruptured by the pushing action of the plunger 43, allowing the drug 201 contained therein to enter the syringe 50. The columnar medicine package is formed by wrapping the medicine 201 with the high polymer material, so that the purity of the medicine 201 can be ensured, the medicine 201 is prevented from being polluted, and the safety of injecting the medicine 201 by a user is improved.

Further, the first end 101 is provided with a blocking piece 104, and the blocking piece 104 is arranged at a position corresponding to the injection tube 50 and movably connected with the first end 101. When the injection pen 100 is not needed, the stopper 104 covers the injection tube 50, so that the tightness of the injection pen 100 is further improved, the purity of the medicine 201 is ensured, and the medicine 201 is prevented from being polluted; when the injection pen 100 is to be used, the stopper 105 is removed, and the medicine 201 is injected to the subcutaneous tissue through the injection tube 50.

Referring to fig. 4, fig. 4 is a schematic circuit diagram of an injection pen provided in the present application. The injection pen 100 further includes a power supply 80 and a power supply controller 90, wherein the power supply controller 90 is configured to control the power supply 80 to supply power to the capacitor 30. Further, the second end 102 is provided with a trigger 70, and the trigger 70 is electrically connected to the power controller 90 to trigger the power controller 90 to control the power source 80 to supply power to the capacitor 30. In this embodiment, the trigger 70 is a button.

Further, referring to fig. 5, in other embodiments, the injection pen 100 further includes a cap 106, and the cap 106 is detachably mounted on the front end of the injection pen barrel 10. By providing the pen cap 106, the medicine 201 in the medicine bin 20 can be further prevented from being contaminated by foreign matters.

Furthermore, a hanging rod 107 is arranged on the pen cap 106, and the hanging rod 107 is arranged to enable a user to carry the injection pen 100 more conveniently, which is beneficial to diversification of application of the injection pen 100.

Before the injection pen 100 is used for injecting the medicine 201 to the subcutaneous tissue of the user, the injection pen 100 is aligned with an injection site, and then the trigger 70 on the injection pen 100 is pressed, so that the trigger 70 triggers the power supply controller 90 to operate, so as to control the power supply 80 to supply power to the capacitor 30 in the injection pen 100, and therefore the charging amount of the capacitor 30 exceeds a preset threshold value, and the capacitor 30 explodes. The high-pressure driving gas generated by explosion drives the liquid pushing plate 41, so that the liquid pushing plate 41 drives the piston 43 to move through the piston shaft 42, the medicine 201 forms a liquid medicine flow which is ejected at a high speed under the pushing action of the piston 43, and the liquid medicine flow is ejected after sequentially passing through the injection tube 50 and the ejection port 103, thereby ensuring that the medicine 201 can be injected into the subcutaneous tissue of a user in a liquid flow manner, and reducing the pain of the user in the process of injecting the medicine 201.

Please refer to fig. 6, fig. 6 is a schematic view of the injection device provided in the present application. The present application further provides an injection device 300, wherein the injection device 300 comprises an injection pen rack 200 and the injection pen (not shown) shown in fig. 1-4. In this embodiment, the power source (not shown) is disposed on the injection pen 100 rack, and the injection pen rack is configured to accommodate and supply power to the injection pen.

In this embodiment, the number of the injection pens is plural, the injection pen placing frame 200 is provided with a plurality of placing holes 201 including a cavity structure corresponding to the plurality of injection pens, the plurality of placing holes 201 are arranged at intervals on the injection pen placing frame 200, and one injection pen is embedded in one placing hole 201 and electrically connected to the power supply 80.

Compared with the prior art, the injection pen 100 in the present application explodes the capacitor 30 by charging the capacitor to generate the high-pressure driving gas, and the high-pressure driving gas is used as the power to push the medicine pushing structure 40 to move, so that the medicine 201 in the medicine bin 20 pushed by the medicine pushing structure 40 is rapidly discharged from the medicine bin 20, instantly passes through epidermal cells in a form of a "liquid needle" and permeates into subcutaneous tissues to complete injection, thereby reducing the pain of a user. Simultaneously, adopt the condenser 30 to come to promote medicine 201 as power and discharge in order to accomplish the injection, on the one hand because of condenser 30 is economical and practical to can reduce injection pen 100's cost, improve injection pen 100's production efficiency, on the other hand because of condenser 30 is small, thereby can reduce injection pen 100's volume, make the syringe portable and easy to operate, increased the convenience of injection.

Finally, it should be noted that the above embodiments are only for illustrating the technical solutions of the present application and not for limiting, and although the present application is described in detail with reference to the above preferred embodiments, it should be understood by those skilled in the art that modifications or equivalent substitutions may be made to the technical solutions of the present application without departing from the spirit and scope of the technical solutions of the present application.

Claims

1. An injection pen, characterized in that it comprises:

the injection pen container, the medicine bin arranged in the injection pen container, the capacitor and the medicine pushing structure;

the medicine bin is internally pre-filled with medicines, and the medicines are selected according to a preset dose;

the medicine pushing structure is movably connected with the medicine bin, and at least part of the medicine pushing structure is positioned in the medicine bin;

the capacitor and the medicine pushing structure are arranged at intervals, and the capacitor is used for exploding to generate high-pressure driving gas when the capacitor is charged to enable the charging amount of the capacitor to exceed a preset threshold value;

2. The injection pen as claimed in claim 1, wherein the drug pushing structure comprises a pushing plate, a piston shaft and a piston connected in sequence, the piston is disposed in the drug chamber, one end of the piston shaft can extend into the drug chamber and is connected to the piston, the other end of the piston shaft is connected to the pushing plate, and the pushing plate is used for pushing the piston to move to discharge the drug under the driving of the high-pressure driving gas.

3. The injection pen of claim 2, further comprising an injection tube disposed at an end of the cartridge facing away from the piston and in communication with the cartridge, wherein the injection tube has an outer diameter smaller than that of the cartridge.

4. Injection pen according to claim 3, characterized in that a protective sleeve is provided between the injection tube and the barrel wall of the injection pen barrel.

5. The injection pen of claim 1, further comprising a power source and a power controller for controlling the power source to supply power to the capacitor.

6. Injection pen according to any one of claims 1 to 5, characterised in that the injection pen barrel has a first end and a second end arranged opposite to the first end, the first end being provided with a stop, which is arranged in correspondence with the position of the injection tube and is movably connected to the first end.

7. The injection pen of claim 6, wherein the second end is provided with a trigger, the trigger being electrically connected to the power controller to trigger the power controller to control the power supply to supply power to the capacitor.

8. The injection pen of claim 6, further comprising a cap removably attached to the front end of the barrel of the injection pen.

9. The injection pen of claim 6, wherein the outer surface of the barrel of the injection pen is further provided with anti-slip threads.

10. An injection device, comprising an injection pen stand and an injection pen according to any one of claims 1 to 9, wherein the power source is disposed on the injection pen stand, and the injection pen stand is configured to receive and supply power to the injection pen.