CN112401942A

CN112401942A - Tissue sample collecting and separating device

Info

Publication number: CN112401942A
Application number: CN202011416705.3A
Authority: CN
Inventors: 于淳; 于岭
Original assignee: Beijing Donglin Fuji Medical Equipment Co ltd
Current assignee: Beijing Donglin Fuji Medical Equipment Co ltd
Priority date: 2020-12-07
Filing date: 2020-12-07
Publication date: 2021-02-26

Abstract

The invention discloses a tissue sample collecting and separating device, which comprises a cup body, a cup cover and a plurality of inner cores, wherein the cup cover is arranged on the cup body; wherein, a plurality of inner core inserting openings are arranged on the periphery of the cup body, and the inner core is inserted into the inner part of the cup body in a pluggable way through the inner core inserting openings; the cup cover is covered on the cup body to seal the cup body, and the cup cover can rotate under the state of covering the cup body; the cup cover is provided with a liquid inlet channel and a liquid outlet channel, the liquid outlet channel is arranged at the center of the cup cover, and the liquid inlet channel is arranged at a position close to the edge of the cup cover; by rotating the cup body, different inner cores are aligned with the liquid inlet channel. According to the biopsy tissue sample collecting and separating device, different inner cores correspond to the liquid inlet channel by rotating the cup body, tissue samples at different parts can be collected in different inner cores, and corresponding collection of tissue samples at different parts can be realized; and, the design of the pluggable inner core facilitates the taking out and detection of the tissue sample after collection.

Description

Tissue sample collecting and separating device

Technical Field

The invention relates to the technical field of medical instruments, in particular to a tissue sample collecting and separating device.

Background

At present, with the development of minimally invasive technology, the examination and treatment under an endoscope are gradually increased, and the collection of the excised tissues under the endoscope is always a difficult problem to be solved. The collection of the excised tissue can be carried out by a suction device of the endoscope, negative pressure suction is carried out, the tissue enters a suction pipeline through a suction cavity of the endoscope, gauze is placed at the suction pipeline to block the tissue, and then the tissue is collected. However, if there are multiple pieces of tissue, the above collection method is inconvenient because it is easy to confuse the tissue. Therefore, it is important to develop a collecting and separating apparatus for tissue to be excised under an endoscope by negative pressure suction.

The publication No. CN206228370U discloses a disposable tissue collector for endoscope suction, which comprises a bottle body, a bottle cap, a gastroscope connecting conduit and a suction apparatus connecting conduit, wherein the bottle cap is rotatably connected with the bottle body; the lower part of the bottle body is provided with a collection chamber, the upper part of the bottle body is provided with a plurality of equally-divided grids, three quarters of the grids are collection grids continuously, the bottom end of each collection grid is provided with a filter screen integrally arranged with the grids, the other quarter of the grids are ventilation grids continuously, and the ventilation grids and the collection grids are correspondingly communicated with the gastroscope connecting conduit respectively. The volume of collecting is big for this collector, and a plurality of samples of same patient can be collected to a plurality of collection check, have avoided losing of sample. However, after the sample is collected in the collection compartment, the sample needs to be taken out of the collection compartment by using tweezers, which is inconvenient for taking out and detecting the sample, and is easy to cause confusion and contamination of the sample during taking out the sample.

Disclosure of Invention

To solve the above technical problems, the present invention provides a tissue sample collecting and separating device.

In order to achieve the technical purpose, the invention provides the following technical scheme:

a tissue sample collecting and separating device comprises a cup body, a cup cover and a plurality of inner cores; wherein, a plurality of inner core inserting openings are arranged on the periphery of the cup body, and the inner core is inserted into the inner part of the cup body in a pluggable way through the inner core inserting openings;

the cup cover is covered on the cup body to seal the cup body, and the cup cover can rotate relative to the cup body in a state of covering the cup body;

the cup cover is provided with a liquid inlet channel and a liquid outlet channel, the liquid outlet channel is arranged at the center of the cup cover, and the liquid inlet channel is arranged at a position close to the edge of the cup cover; by rotating the cup body, different inner cores are aligned with the liquid inlet channel.

Preferably, the inner core comprises a connecting plate, a collecting box and a handle; the connecting plate is arc-shaped, the handle is arranged on the outer side of the connecting plate, and the collecting box is arranged on the inner side of the connecting plate.

Preferably, the collecting box comprises a fan-shaped bottom surface and two rectangular side surfaces, and a plurality of filtering holes are arranged in the fan-shaped bottom surface and/or the rectangular side surfaces.

Wherein, preferably, two sides of the collecting box are respectively provided with an elastic buckle which is connected with the inner side of the connecting plate; on the cup body, two inner core fixing grooves are respectively arranged on two sides of each inner core insertion hole and are used for being matched with the elastic buckles of the inner cores.

Wherein preferably, the lower edge of the inner core insertion opening is close to the bottom of the cup body; the inner core is arranged close to the bottom of the cup body, and the height of the inner core exceeds 1/2 of the height of the cup body.

Wherein preferably, the inside peripheral zone that is divided into central zone and is used for setting up the inner core of cup, and the peripheral zone divides into a plurality of inner core inserting regions and a plurality of interval regions that supply the inner core to insert, and inner core inserting region and interval region alternate the setting.

Preferably, guide baffles which respectively extend from the left side and the right side of the inner core insertion opening along the radial direction are arranged in the cup body, and the bottom of the U-shaped bottom support is connected with the bottom of the cup body; the cup body is also internally provided with a U-shaped bottom support connected with the bottom edge of the inner core insertion hole, and the bottom of the U-shaped bottom support is connected with the bottom of the cup body.

Preferably, a serial number mark is arranged on the outer wall of the cup body above each inner core insertion opening.

Preferably, the liquid inlet channel and the liquid outlet channel both vertically penetrate through the cup cover;

one end of the liquid inlet channel extends towards the inside of the cup body and extends to a position higher than the upper edge of the inner core insertion opening, and the other end of the liquid inlet channel protrudes out of the cup cover;

one end of the liquid outlet channel extends towards the inside of the cup body and extends to a position close to the bottom of the cup body, and the other end of the liquid outlet channel protrudes above the cup cover.

Wherein, preferably, the periphery of the cup cover is provided with a positioning part which is positioned on the same straight line with the liquid inlet channel and the liquid outlet channel.

The tissue sample collecting and separating device comprises a cup body, a cup cover and a plurality of pluggable inner cores, wherein different inner cores correspond to a liquid inlet pipeline by rotating the cup body, so that tissue samples at different parts can be collected in different inner cores, and the corresponding collection of the tissue samples at different parts can be realized; moreover, due to the design of the pluggable inner core, the tissue sample can be conveniently taken out and detected after being collected, the operation is simplified, and the tissue sample is not easily polluted.

Drawings

FIG. 1 is a schematic view of the overall construction of a biopsy tissue sample collection and separation device provided by the present invention;

FIG. 2 is a front view of the lid of FIG. 1;

FIG. 3 is a schematic top view of the lid of FIG. 1;

FIG. 4 is a bottom view of the lid of FIG. 1;

FIG. 5 is a schematic view of the cup and core of FIG. 1 in an assembled state;

FIG. 6 is a schematic top view of the cup of FIG. 1;

FIG. 7 is a perspective view of the cup of FIG. 1;

FIG. 8 is a schematic top view of the core of FIG. 1;

fig. 9 is a side view of the core of fig. 1.

Detailed Description

In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is described in further detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.

It will be understood that when an element is referred to as being "secured to" or "disposed on" another element, it can be directly on the other element or be indirectly on the other element. When an element is referred to as being "connected to" another element, it can be directly connected to the other element or be indirectly connected to the other element.

It will be understood that the terms "length," "width," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "inner," "outer," and the like, refer to an orientation or positional relationship as shown in the drawings for convenience in describing the application and to simplify the description, and do not indicate or imply that the referenced device or element must have a particular orientation, be constructed and operated in a particular orientation, and thus should not be considered as limiting the application.

Furthermore, the terms "first", "second" and "first" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of the present application, "a plurality" means two or more unless specifically limited otherwise.

As shown in figure 1, the biopsy tissue sample collecting and separating device provided by the invention comprises a cup cover 1, a cup body 2 and a plurality of inner cores 3. The cup cover 1 is a circular thin sheet, the cup body 2 is a cylindrical shape, the cup cover 1 covers the circular cup body 2 to seal the cup body 2, and the cup cover 1 can rotate relative to the cup body 2 under the state of covering the cup body 2. A plurality of core insertion ports 25 are provided on the outer periphery of the cup body 2, and the plurality of cores 3 are provided in the cup body 2 so as to be insertable and removable through the plurality of core insertion ports 25.

Specifically, as shown in fig. 2-4, the lid 1 is provided with a first channel 11 and a second channel 12, both the first channel 11 and the second channel 12 vertically penetrate through the lid 1, one end (the lower end shown in fig. 2) of the first channel extends into the cup body 2, and the other end (the upper end shown in fig. 2) protrudes above the lid 1. Wherein the first channel 11 extends to one end (the lower end as shown in fig. 2) of the cup body 2 to a position close to the bottom of the cup body 2; the second channel 12 extends to one end (lower end as viewed in fig. 2) of the cup body 2 to a position higher than the upper edge of the core 3 inside the cup body 2, that is, to a position higher than the upper edge of the core insertion port 20 of the cup body 2.

The first channel 11 is positioned at the circle center of the cup cover 1 and is used for pumping out waste liquid in the cup body 2. The second channel 12 is positioned between the first channel 11 and the edge of the cup cover 1 and is arranged at a position close to the edge of the cup cover 1; the arrangement position of the second channel 12 on the cup cover 1 corresponds to the arrangement area 20B of the inner cores 3 in the cup body 2.

The periphery of the cup cover 1 is provided with a positioning part 13, and the positioning part 13, the first channel 11 and the second channel 12 are positioned on the same straight line. When the cup cover 1 rotates to the position part 13 to align with one of the inner cores 3, the second channel 12 is located above the inner core 3 and is used for guiding the waste liquid into the inner part of the inner core 3. The positioning portion 13 may be a positioning protrusion as shown in the drawings, and the shape of the positioning protrusion is not limited to a triangle; the detent 13 may also be other visible markings such as a pointer image printed on the periphery of the lid 1.

The periphery of the cup cover 1 is also provided with a plurality of bulges 14 for enhancing the friction force between the cup cover 1 and a hand and facilitating the rotation of the cup cover 1. The number of the projections 14 is not limited, and may be any number.

Be provided with annular slot at the lower extreme of bowl cover 1 to be provided with a plurality of outstanding buckles 15 on the lateral wall of slot, a plurality of buckles 15 distribute along bowl cover 1's periphery, be used for with the annular flange 27 cooperation that sets up in 2 upper ends of cup, realize

bowl cover

1 and 2 block, and, when bowl cover 1 seals cup 2, cup 2 can be rotatory for bowl cover 1. The number of the catches 15 is not limited.

When in use, the collecting and separating device for the biopsy tissue sample is connected in a suction pipeline connected with a suction device of the biopsy device, wherein the first channel 11 is a liquid outlet channel, and the upper end of the first channel 11 is connected with the suction device and the waste liquid collecting device; the second channel 12 is a liquid inlet channel, the upper end of which is connected to the biopsy site by a suction conduit. Under the action of the suction device, waste liquid sucked out from the biopsy position by the suction device enters the inner core 3 through the second channel 12, is sucked away from the first channel 11 after being filtered, enters the waste liquid collecting device, and tissues in the waste liquid are separated into the inner core 3. When the biopsy position changes, the rotatable cup 2 replaces the inner core 3 corresponding to the second channel 12, thereby separating tissue samples cut from different biopsy positions into different inner cores 3.

As shown in fig. 5, the cup body 2 is a cylindrical shell with an open upper end, wherein the inside of the cup body 2 is divided into a central area 20A and an outer peripheral area 20B for disposing the core 3. A plurality of cores 3 are uniformly provided in the outer peripheral region 20B of the cup body 2 in a pluggable manner. The inner core 3 is positioned near the bottom of the cup body 2 and the height of the inner core 3 exceeds 1/2, which is preferably 3/4, which may exceed the height of the cup body 2, which provides a larger tissue sample collection space for each inner core 3.

As shown in fig. 6 and 7, the cup body 2 is a cylindrical shape with an opening on one side, and an annular flange 27 is arranged on the outer wall of the upper end of the cup body 2 along the circumferential direction and is used for being matched with the buckle 15 on the cup cover 1 to realize the clamping between the cup body 2 and the cup cover 1. In the process of inserting the upper end of cup 2 into the slot at the lower end of cup lid 1, annular flange 27 deforms snap 15, and after annular flange 27 exceeds snap 15, annular flange 27 is limited to the inner side of snap 15, so that connection between cup 2 and cup lid 1 is realized, and cup 2 can rotate around first channel 11 relative to cup lid 1.

A plurality of core insertion holes 25 are formed in a side surface of the outer circumference of the cup body 2, and core fixing grooves 26 are formed at both sides of each core insertion hole 25. In the cup body 2 provided in the present embodiment, 6

core insertion ports

25 and 12 core fixing grooves 26 are provided. The number of cores 3 and the number of core insertion ports 25 may be changed according to actual needs.

As shown in fig. 5 and 6, an outer peripheral area 20B corresponding to the core 3 inside the cup body 2 is divided into a plurality of core insertion areas 21 into which the core 3 is inserted and a plurality of partition areas 22, and the core insertion areas 21 and the partition areas 22 are provided at intervals.

A core insertion opening 25 is opened on the outer wall of the core insertion region 21, a lower edge of the core insertion opening 25 is close to the bottom of the cup body 2, and the core 3 is provided in the cup body 2 through the core insertion opening 25 in a pluggable manner. The inside of the cup body 2 is provided with guide baffles 23 which respectively extend from the left side and the right side of the inner core insertion opening 25 to the inside of the cup body, the guide baffles 23 extend along the radial direction of the cup body 2, and the bottom of the guide baffles 23 is connected with the bottom of the cup body 2; the length of the guide baffle 23 is smaller than the radius of the cup body 2 and is close to the extending depth of the inner core 3; the height of the guide baffle 23 is less than that of the inner core 3; the guide baffle 23 is spaced from the side wall of the inner core 3, so that waste liquid can flow into the cup body 2 from the side wall of the inner core 3 conveniently. The cup body 2 is also internally provided with a bottom support 24 connected with the bottom edge of the inner core inserting hole 25, the bottom support 24 is arranged at the bottom of the cup body 2, and the bottom of the bottom support 24 is connected with the bottom of the cup body 2 and used for supporting the inner core 3 from the bottom. The bottom support 24 is U-shaped and is used for supporting the edge of the bottom of the inner core 3, and a space for the waste liquid to flow is formed in the middle of the bottom support 24, so that the waste liquid can flow into the cup body 2 from the bottom of the inner core 3 conveniently. Waste liquid can flow into the cup body 2 from the space between the bottom of the core 3 and the bottom of the cup body 2 and the space between the side wall of the core 3 and the guide baffle 23 and be sucked out of the cup body 2 from the first channel 11 in the center of the cup body 2. Preferably, the deflector 23, the mounting 24 and the entire shell of the cup 2 are made in one piece from the same material.

The core fixing grooves 26 are formed in the outer wall of the partition region 22, two core fixing grooves 26 are formed between the two core insertion openings 25, and the core fixing grooves 26 are used for being matched with the elastic buckles 33 of the core 3 to fix the core 3.

Further, on the outer wall of the cup body 2, a serial number mark 28 for marking a serial number corresponding to the core 3 is provided above each core insertion opening 25. In this embodiment,

numerals

1, 2, 3, 4, 5, 6 are provided above the 6 core insertion ports 25, respectively.

As shown in fig. 8 and 9, the core 3 includes a collection box 30, a connection plate 31, a handle 32, and a resilient catch 33. Preferably, the collecting box 30, the connecting plate 31, the handle 32 and the elastic buckle 33 are integrally made of the same material. Wherein, the side of the connecting plate 31 facing the center of the cup body is taken as the inner side, the handle 31 is arranged at the outer side of the connecting plate 32, and the collecting box 30 is arranged at the inner side of the connecting plate 32. The connecting plate 32 connecting the collecting box 30 and the handle 31 is in the shape of a circular arc, and the connecting plate 32 is attached to the periphery of the cup body 2, so that when the inner cores 3 are inserted into the cup body 2, the connecting plate 31 and the outer wall of the cup body 2 are surrounded to be circular. The handle 31 is convenient for the operation of plugging the inner core 3, and the shape and the material of the handle can be changed according to the actual situation.

The shape of the collecting box 30 matches with the shape of the area defined by the two guiding baffles 23 and the bottom support 24 inside the core insertion opening 25, the shape in this embodiment is a structure gradually reduced from outside to inside, the collecting box 30 is a sector cylinder with an upper opening when viewed from top to bottom, and the sector cylinder is a cylinder with a sector cross section. Preferably, the cross section of the collecting box 30 is reduced from top to bottom in order to form a gap between the collecting box 30 and the guide baffle 23 for the flow of the waste liquid. The collecting box 30 in this embodiment has a fan-shaped bottom surface 301 and two rectangular side surfaces 302, and a plurality of filter holes 303 are provided in the fan-shaped bottom surface 301 and the rectangular side surfaces 302, respectively, for the circulation of waste liquid. By providing the filter holes 303 in both the bottom surface 301 and the side surface 302 of the collecting box 30, the flow rate of the waste liquid can be increased, and the resistance to the flow of the waste liquid can be reduced. Of course, the filter holes 303 may be provided only in the fan-shaped bottom surface 301 or the rectangular side surface 302, and the resistance to the flow of the waste liquid may be larger in this arrangement than in the case where the filter holes 303 are provided in all of the three surfaces.

An elastic catch 33 is provided on each side of the collecting case 30, and the elastic catch 33 is connected to the inner side of the connecting plate 32. The elastic catch 33 includes a connecting arm 331 and a hook 332 provided at the front end of the connecting arm 331, and the hook 332 has two curved contact surfaces 333 and 334 on its side surface and forms a tip 335 protruding in a direction away from the collecting box 30 at a position where the two contact surfaces intersect, facilitating insertion and extraction of the elastic catch 33. Wherein the first contact surface 333 is closer to the connection plate 31 than the second contact surface 334.

When the plunger 3 is inserted inward, the elastic catch 33 is inserted into the plunger fixing groove 26, the hook 332 is in contact with the edge of the plunger fixing groove 26, and the contact position is moved from the first contact surface 333 to the tip portion 335, in the above process, the connection arm 331 of the elastic catch 33 is slightly deformed, and after the contact position exceeds the tip portion 335, the connection arm 331 is restored to the original shape, and the hook 332 is caught at the inner side of the inner wall of the cup body 2, preventing the movement of the plunger 3.

When the plunger 3 is pulled outward, the contact position of the hook 332 with the plunger fixing groove 26 moves along the second contact surface 334, in the above process, the connection arm 331 of the elastic catch 33 is slightly deformed, and when the contact position exceeds the tip 335, the hook 332 slides outward along the plunger insertion groove 26, thereby pulling out the plunger 3.

The tissue sample collecting and separating device provided by the invention is suitable for collecting and separating the tissue sample in the process of obtaining the human tissue sample through surgical excision. Tissue samples include tumors, diseased tissues, and other control tissues (including near-cancerous tissues, paracancerous tissues, normal tissues, etc.).

When the mixed liquid of the biopsy tissue sample and the waste liquid enters the inner core 3 through the liquid inlet channel (i.e., the second channel 12), the inner core 3 can separate the biopsy tissue sample from the waste liquid, so that the biopsy tissue sample is collected in the collection box 30, the waste liquid is automatically discharged, and the waste liquid is drawn out through the liquid outlet channel (i.e., the first channel 11); during biopsy, different tissue samples can be collected in different inner cores 3 by rotating the cup lid 1, achieving the separation requirement. In combination with markings (e.g., 1, 2, 3, … …) provided on the cup 2, tissue samples from different biopsy locations may be obtained for ease of testing and analysis. The suction apparatus may be an endoscopic suction apparatus, and the waste liquid sucked by the suction pump flows into the waste liquid collection bottle.

In summary, the biopsy tissue sample collecting and separating device provided by the invention comprises a cup body, a cup cover and a plurality of pluggable inner cores, different inner cores correspond to the liquid inlet channel by rotating the cup body, tissue samples at different parts can be collected in different inner cores, and corresponding collection of tissue samples at different parts can be realized; moreover, due to the design of the pluggable inner core, the tissue sample can be conveniently taken out and detected after being collected, the operation is simplified, and the tissue sample is not easily polluted.

The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents and improvements made within the spirit and principle of the present invention are intended to be included within the scope of the present invention.

Claims

1. A tissue sample collecting and separating device is characterized by comprising a cup body, a cup cover and a plurality of inner cores; wherein the content of the first and second substances,

a plurality of inner core insertion holes are formed in the periphery of the cup body, and the inner cores are inserted into the cup body through the inner core insertion holes;

the cup cover is covered on the cup body to seal the cup body, and can rotate relative to the cup body in a state of covering the cup body;

2. The tissue sample collection and separation device of claim 1, wherein:

the inner core comprises a connecting plate, a collecting box and a handle; the connecting plate is arc-shaped, the handle is arranged on the outer side of the connecting plate, and the collecting box is arranged on the inner side of the connecting plate.

3. The tissue sample collection and separation device of claim 2, wherein:

the collecting box comprises a fan-shaped bottom surface and two rectangular side surfaces, and a plurality of filtering holes are arranged in the fan-shaped bottom surface and/or the rectangular side surfaces.

4. The tissue sample collection and separation device of claim 2, wherein:

two sides of the collecting box are respectively provided with an elastic buckle, and the elastic buckles are connected to the inner side of the connecting plate;

and the two sides of each inner core insertion hole are respectively provided with an inner core fixing groove which is used for being matched with the elastic buckle.

5. The tissue sample collection and separation device of claim 1, wherein:

the lower edge of the inner core insertion opening is close to the bottom of the cup body;

the inner core is arranged close to the bottom of the cup body, and the height of the inner core exceeds 1/2 of the height of the cup body.

6. The tissue sample collection and separation device of claim 1, wherein:

the cup body is internally divided into a central area and a peripheral area for arranging the inner core, the peripheral area is divided into a plurality of inner core inserting areas for inserting the inner core and a plurality of interval areas, and the inner core inserting areas and the interval areas are arranged at intervals.

7. The tissue sample collection and separation device of claim 1, wherein:

guide baffles which respectively extend from the left side and the right side of the inner core insertion opening along the radial direction are arranged in the cup body, and the bottom of each guide baffle is connected with the bottom of the cup body;

the cup body is also internally provided with a U-shaped bottom support connected with the bottom edge of the inner core insertion hole, and the bottom of the U-shaped bottom support is connected with the bottom of the cup body.

8. The tissue sample collection and separation device of claim 1, wherein:

and a serial number mark is arranged above each inner core insertion hole on the outer wall of the cup body.

9. The tissue sample collection and separation device of claim 1, wherein:

the liquid inlet channel and the liquid outlet channel penetrate through the cup cover up and down;

one end of the liquid outlet channel extends towards the inside of the cup body and extends to a position close to the bottom of the cup body, and the other end of the liquid outlet channel protrudes out of the cup cover.

10. A tissue sample collection and separation device according to claim 1 wherein:

the periphery of the cup cover is provided with a positioning part, and the positioning part, the liquid inlet channel and the liquid outlet channel are positioned on the same straight line.