CN112400866A - Incubator for organ preservation - Google Patents
Incubator for organ preservation Download PDFInfo
- Publication number
- CN112400866A CN112400866A CN202011410772.4A CN202011410772A CN112400866A CN 112400866 A CN112400866 A CN 112400866A CN 202011410772 A CN202011410772 A CN 202011410772A CN 112400866 A CN112400866 A CN 112400866A
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- Prior art keywords
- temperature
- control panel
- organ
- box body
- box
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000000082 organ preservation Substances 0.000 title claims abstract description 24
- 238000004321 preservation Methods 0.000 claims abstract description 31
- 238000007789 sealing Methods 0.000 claims abstract description 18
- 238000005192 partition Methods 0.000 claims abstract description 11
- 239000000463 material Substances 0.000 claims abstract description 5
- 230000008878 coupling Effects 0.000 claims description 3
- 238000010168 coupling process Methods 0.000 claims description 3
- 238000005859 coupling reaction Methods 0.000 claims description 3
- 210000000056 organ Anatomy 0.000 abstract description 51
- 230000000694 effects Effects 0.000 abstract description 11
- 230000009286 beneficial effect Effects 0.000 abstract description 2
- 238000001514 detection method Methods 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 description 13
- 238000002054 transplantation Methods 0.000 description 12
- 238000005516 engineering process Methods 0.000 description 3
- 238000000338 in vitro Methods 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 210000003734 kidney Anatomy 0.000 description 2
- 238000011084 recovery Methods 0.000 description 2
- 206010053159 Organ failure Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 238000005138 cryopreservation Methods 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 238000005265 energy consumption Methods 0.000 description 1
- 238000007710 freezing Methods 0.000 description 1
- 230000008014 freezing Effects 0.000 description 1
- 239000005457 ice water Substances 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 238000009413 insulation Methods 0.000 description 1
- 208000028867 ischemia Diseases 0.000 description 1
- 231100000518 lethal Toxicity 0.000 description 1
- 230000001665 lethal effect Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 230000017074 necrotic cell death Effects 0.000 description 1
- 230000001338 necrotic effect Effects 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 230000002980 postoperative effect Effects 0.000 description 1
- 238000004393 prognosis Methods 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 230000010410 reperfusion Effects 0.000 description 1
- 230000008054 signal transmission Effects 0.000 description 1
- 230000003068 static effect Effects 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/02—Preservation of living parts
- A01N1/0236—Mechanical aspects
- A01N1/0242—Apparatuses, i.e. devices used in the process of preservation of living parts, such as pumps, refrigeration devices or any other devices featuring moving parts and/or temperature controlling components
- A01N1/0252—Temperature controlling refrigerating apparatus, i.e. devices used to actively control the temperature of a designated internal volume, e.g. refrigerators, freeze-drying apparatus or liquid nitrogen baths
- A01N1/0257—Stationary or portable vessels generating cryogenic temperatures
Abstract
The invention discloses a constant temperature box for organ preservation, which comprises a box body, a sealing cover, a connecting buckle, a lifting handle, a control panel, a display screen, an indicator light, an inner wall of the box body, a heat preservation layer, a temperature regulator, a power box, a slide bar, a spring, a support plate, a placement groove, a partition plate and a temperature sensor. The invention has the beneficial effects that: the baffle adopts the material preparation that the heat conductivility is good to form, the temperature of detection donor's organ that the temperature sensor of being convenient for can be timely, the both sides of backup pad are provided with the through-hole with slide bar matched with, play certain spacing guard action to donor's organ, temperature sensor's output links to each other with control panel's input, control panel's output links to each other with the input of pilot lamp, guarantee the temperature control effect, be equipped with two constant temperature regulators, and temperature regulator's input links to each other with control panel's output, in order to improve accuse temperature efficiency, the backup pad upper surface is provided with the spacing hole that suits with the settling tank, be convenient for improve settling tank stability, guarantee the security of preserving the organ.
Description
Technical Field
The invention relates to a constant-temperature storage box, in particular to a constant-temperature box for organ storage, and belongs to the technical field of medical instruments.
Background
The purpose of organ transplantation is to replace organs with functions lost due to lethal diseases, and transplanted individuals can have corresponding organ functions again, so that the organ transplantation method is the only effective treatment method for treating a plurality of end-stage organ failure diseases. The donor organ required in organ transplantation originates from another person, and the organ needs to be harvested from the donor. If the obtained isolated organ is not well preserved, the obtained isolated organ will be necrotic in a short period of time, and cannot be used for transplantation operation. The importance of organ preservation techniques in the field of organ transplantation is therefore self-evident. The organ preservation technology is a measure for keeping the activity of an organ for transplantation in an isolated blood-free state or rapidly recovering the activity of the organ for transplantation, and due to the extreme shortage of donor organs and the fact that an improper preservation mode possibly has great influence on the prognosis of the organ transplantation operation and the postoperative organ function recovery, a reasonably proper organ preservation technology plays an important role in the organ transplantation operation.
The most common organ preservation method clinically at present is a low-temperature preservation method, and organ energy consumption is reduced through static low temperature, so that the preservation time of organs is prolonged. Most incubator does not have the function of detecting the temperature in the incubator, the actual temperature of the preserved organ cannot be monitored in real time, the constant and proper preservation temperature cannot be provided for the preserved organ exactly and effectively, the optimal preservation effect cannot be achieved, and the incidence rate of complications after transplantation cannot be increased. In addition, in the actual use process, if the actual preservation temperature of the organ is lower than 2 ℃ because of direct contact with ice blocks, the phenomenon of partial freezing necrosis of the organ can be caused.
With the further understanding and research on organ preservation technology in these years, the preservation of isolated organs is no longer limited to cryopreservation, and the newer concept of organ preservation is gradually being raised. The concept of normal temperature and sub-normal temperature preservation of organs has been proposed, and studies show that the method for preserving the organs in vitro by combining normal temperature or sub-normal temperature with the oxygen carrier can more effectively relieve the injury caused by ischemia reperfusion and achieve the effect of prolonging the preservation time. Patent 2014103847003.9 discloses a cryo-or sub-normothermic kidney preservation apparatus that has been considered for organ preservation at sub-normothermia to improve the quality of kidney preservation. Therefore, more and more preservation modes are suggested, and a single low-temperature incubator cannot be applied to the development of the current various preservation modes.
Disclosure of Invention
The present invention has been made to solve the above problems, and an object of the present invention is to provide an incubator for organ preservation.
The invention realizes the purpose through the following technical scheme: a thermotank for organ preservation comprises a box body, a sealing cover, a connecting buckle, a lifting handle, a control panel, a display screen, an indicator light, the inner wall of the box body, a heat preservation layer, a temperature regulator, a power supply box, a sliding rod, a spring, a supporting plate, a placing groove, a partition plate and a temperature sensor; the box body, the temperature regulator and the placing groove form a main body structure of the device, a sealing cover is arranged at the upper end of the box body and fixedly connected with the box body through a connecting buckle, lifting handles are fixedly arranged at two sides of the box body, a control panel is fixedly arranged on the surface of the sealing cover, a display screen is fixedly arranged on the control panel, an indicator lamp fixedly connected to the sealing cover is arranged at the lower side of the control panel, the box body comprises a box body inner wall, a heat preservation layer is arranged at the inner side of the box body inner wall, the temperature regulator is fixedly connected to one side of the heat preservation layer, which is far away from the box body inner wall, a power supply box is arranged at the center position of the lower side of the box body inner wall, slide bars are symmetrically arranged on the upper surface of the box body inner wall, a supporting plate is connected onto the slide bars, the inside fixed joint of resettlement groove has the baffle, the downside of baffle is provided with the temperature sensor of rigid coupling at resettlement inslot bottom surface.
Preferably, in order to facilitate the temperature sensor to detect the temperature of the organ in time, the partition plate is made of a material with good heat conductivity.
Preferably, in order to facilitate the movement of the support plate without the obstruction of the slide bar, the support plate plays a certain limiting protection role on the organ in the organ placing process, through holes matched with the slide bar are arranged on two sides of the support plate, and the inner diameter of each through hole is larger than the diameter of the slide bar.
Preferably, when the temperature sensor detects that the temperature of preserving the organ is not in the temperature zone of settlement, for the convenience of being convenient for, give control panel with signal transmission, control panel control indicator twinkling to remind medical personnel to adjust the incasement temperature, reach the organ preservation effect that needs, temperature sensor's output links to each other with control panel's input, and control panel's output links to each other with the input of pilot lamp.
Preferably, in order to provide a stable temperature control effect, the number of the temperature regulators is two, and the input end of the temperature regulator is connected with the output end of the control panel.
Preferably, in order to improve the stability of the placement groove and ensure the safety of the organ in-vitro preservation process, the upper surface of the supporting plate is provided with a limiting hole matched with the placement groove.
The invention has the beneficial effects that: the incubator for organ preservation is reasonable in design, the partition plate is made of materials with good heat conduction performance, a temperature sensor can detect the temperature of organs in time conveniently, through holes matched with the slide rods are formed in two sides of the support plate, the inner diameters of the through holes are larger than the diameters of the slide rods, the support plate can move freely on the slide rods, therefore, a certain limiting protection effect on the organs is achieved in the organ placing process, the output end of the temperature sensor is connected with the input end of the control panel, the output end of the control panel is connected with the input end of the indicator light, when the temperature sensor detects that the temperature of the organs is not in a set temperature area, signals are sent to the control panel, the control panel controls the indicator light to flicker, accordingly, medical staff are reminded of abnormal organ temperature and timely adjustment is achieved, the organ preservation effect is improved, and the number of the temperature regulators is two, and the input end of the temperature regulator is connected with the output end of the control panel, so that the temperature control efficiency is improved conveniently, the upper surface of the supporting plate is provided with a limiting hole matched with the placing groove, the stability of the placing groove is improved conveniently, and the safety and the stability of the preserved organs are ensured. In addition, in order to protect the environment and save the manufacturing cost of the heat preservation box, a refrigerating device is not added in the organ preservation box, and the transplanted organs are generally preserved in vitro only in a short time, and the effect of cooling is achieved by artificially adding a low-temperature solution.
Drawings
FIG. 1 is a schematic front view of the present invention;
FIG. 2 is a schematic cross-sectional view of the present invention;
FIG. 3 is a schematic top view of the present invention.
In the figure: 1. the temperature control box comprises a box body, 2 sealing covers, 3 connecting buckles, 4 lifting handles, 5 control panels, 6 display screens, 7 indicator lamps, 8 box inner walls, 9 heat preservation layers, 10 temperature regulators, 11 power boxes, 12 sliding rods, 13 springs, 14 supporting plates, 15 placing grooves, 16 partition plates, 17 and temperature sensors.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Referring to fig. 1-3, a thermostat for organ preservation comprises a box body 1, a sealing cover 2, a connecting buckle 3, a lifting handle 4, a control panel 5, a display screen 6, an indicator light 7, a box body inner wall 8, a heat insulation layer 9, a temperature regulator 10, a power supply box 11, a sliding rod 12, a spring 13, a support plate 14, a placement groove 15, a partition plate 16 and a temperature sensor 17; the box body 1, the temperature regulator 10 and the placing groove 15 form a main body structure of the device, a sealing cover 2 is arranged at the upper end of the box body 1, the sealing cover 2 is fixedly connected with the box body 1 through a connecting buckle 3, lifting handles 4 are fixedly arranged at two sides of the box body 1, a control panel 5 is fixedly arranged on the surface of the sealing cover 2, a display screen 6 is fixedly arranged on the control panel 5, an indicator lamp 7 fixedly connected to the sealing cover 2 is arranged at the lower side of the control panel 5, the box body 1 comprises a box body inner wall 8, a heat preservation layer 9 is arranged at the inner side of the box body inner wall 8, the temperature regulator 10 is fixedly connected to one side of the heat preservation layer 9, which is far away from the box body inner wall 8, a power supply box 11 is arranged at the center position of the lower side of the box body inner wall 8, a sliding rod 12 is, and a spring 13 is fixedly installed between the sliding rod 12 and the supporting plate 14, a placing groove 15 is fixedly arranged on the upper surface of the supporting plate 14, a partition plate 16 is fixedly clamped inside the placing groove 15, and a temperature sensor 17 fixedly connected to the inner bottom surface of the placing groove 15 is arranged on the lower side of the partition plate 16.
The partition board 16 is made of a material with good heat conductivity, so that the temperature sensor 17 can detect the temperature of the donor organ in time, through holes matched with the slide bars 12 are formed in the two sides of the support board 14, the inner diameter of each through hole is larger than the diameter of each slide bar 12, the support board 14 can move freely in the slide bars 12, so that a certain limiting protection effect on the organ is achieved in the organ placing process, the output end of the temperature sensor 17 is connected with the input end of the control panel 5, the output end of the control panel 5 is connected with the input end of the indicator light 7, when the temperature sensor 17 detects that the temperature of the organ is not in a set area, a signal is sent to the control panel 5, the control panel 5 controls the indicator light 7 to flash, so that medical staff is reminded to adjust the temperature in the preservation box, the preservation efficiency is improved, and the two temperature regulators 10 are arranged, and the input of temperature regulator 10 links to each other with control panel 5's output, is convenient for improve accuse temperature efficiency, reduces the hand labor cost, the backup pad 14 upper surface is provided with the spacing hole that suits with resettlement groove 15, is convenient for improve resettlement groove 15 stability, guarantees that the temperature regulation process goes on steadily.
The working principle is as follows: when the incubator is used for organ preservation, firstly the sealing cover 2 is opened, a medical worker needs to add ice-water mixture of 0-4 ℃ into the incubator in advance, a required preservation temperature interval is set through the control panel 5, then the sealing cover 2 is covered and sealed for a period of time, the incubator is controlled to be automatically stopped after being adjusted to the preset temperature, then an organ preservation bag containing organs to be preserved is slowly placed in the placing groove 15, organ preservation liquid is filled in the organ preservation bag in advance, the temperature sensor 17 sends a signal to the control panel 5, the instant temperature of the preserved organs can be monitored at any time, in the process of organ preservation and transportation, if the surface temperature of the organs exceeds the preset preservation temperature range, the temperature sensor 17 sends the signal to the control panel 5, the control panel 5 controls the indicator light 7 to flash, and the medical worker is reminded to adjust the temperature in the incubator in time, the preservation temperature can be adjusted according to medical personnel's demand in the whole organ preservation process, has improved the security of isolated organ greatly to before the transplantation operation, medical personnel can pass through control panel with the quick rewarming of isolated organ, the recovery of organ function before the assurance transplantation operation.
Furthermore, it should be understood that although the present description refers to embodiments, not every embodiment may contain only a single embodiment, and such description is for clarity only, and those skilled in the art should integrate the description, and the embodiments may be combined as appropriate to form other embodiments understood by those skilled in the art.
Claims (6)
1. An incubator for organ preservation, characterized in that: the portable temperature control box comprises a box body (1), a sealing cover (2), a connecting buckle (3), a lifting handle (4), a control panel (5), a display screen (6), an indicator light (7), a box body inner wall (8), a heat preservation layer (9), a temperature regulator (10), a power supply box (11), a sliding rod (12), a spring (13), a supporting plate (14), a placing groove (15), a partition plate (16) and a temperature sensor (17);
the device comprises a box body (1), a temperature regulator (10) and a placement groove (15), wherein the box body (1), the temperature regulator and the placement groove (15) form a main body structure of the device, a sealing cover (2) is arranged at the upper end of the box body (1), the sealing cover (2) is fixedly connected with the box body (1) through a connecting buckle (3), lifting handles (4) are fixedly arranged on two sides of the box body (1), a control panel (5) is fixedly arranged on the surface of the sealing cover (2), a display screen (6) is fixedly arranged on the control panel (5), and an indicator lamp (7) fixedly connected onto the sealing cover (2) is arranged on the lower side of the control panel (5;
box (1) includes box inner wall (8), the inboard of box inner wall (8) is provided with one deck heat preservation (9), one side rigid coupling that deviates from box inner wall (8) of heat preservation (9) has temperature regulator (10), the downside central point of box inner wall (8) puts and is provided with power pack (11), and the upper surface symmetry of box inner wall (8) is provided with slide bar (12), be connected with backup pad (14) on slide bar (12), and fixed mounting has spring (13) between slide bar (12) and backup pad (14), the last fixed surface of backup pad (14) is provided with resettlement groove (15), the inside fixed joint of resettlement groove (15) has baffle (16), the downside of baffle (16) is provided with temperature sensor (17) of rigid coupling bottom surface in resettlement groove (15).
2. An incubator according to claim 1, wherein: the partition plate (16) is made of a material with good heat-conducting property.
3. An incubator according to claim 1 or 2, wherein: through holes matched with the sliding rods (12) are formed in the two sides of the supporting plate (14), and the inner diameter of each through hole is larger than the diameter of each sliding rod (12).
4. The incubator according to claim 3, wherein: the output end of the temperature sensor (17) is connected with the input end of the control panel (5), and the output end of the control panel (5) is connected with the input end of the indicator lamp (7).
5. An incubator according to claim 4, wherein: the temperature regulators (10) are arranged in two numbers, and the input ends of the temperature regulators (10) are connected with the output end of the control panel (5).
6. An incubator according to claim 5, wherein: and the upper surface of the supporting plate (14) is provided with a limiting hole matched with the placing groove (15).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011410772.4A CN112400866A (en) | 2020-12-04 | 2020-12-04 | Incubator for organ preservation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011410772.4A CN112400866A (en) | 2020-12-04 | 2020-12-04 | Incubator for organ preservation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN112400866A true CN112400866A (en) | 2021-02-26 |
Family
ID=74830356
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202011410772.4A Pending CN112400866A (en) | 2020-12-04 | 2020-12-04 | Incubator for organ preservation |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN112400866A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113317311A (en) * | 2021-05-17 | 2021-08-31 | 上海理工大学 | Preservation and transportation device for isolated organs |
| EP4344542A1 (en) * | 2022-09-30 | 2024-04-03 | Aferetica S.r.l. | Device for the storage and transport of biological material |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20140017664A1 (en) * | 2012-07-10 | 2014-01-16 | Lifeline Scientific, Inc. | Temperature sensing in organ preservation apparatus |
| CN205431770U (en) * | 2015-12-25 | 2016-08-10 | 深圳市第二人民医院 | Pancreas transplantation is with active fresh -keeping case |
| CN207355343U (en) * | 2017-09-29 | 2018-05-15 | 韩彤霞 | A kind of human organ transplant donor stores carrying device |
| CN110342104A (en) * | 2019-07-17 | 2019-10-18 | 蒋欣 | A kind of active shock insulation organ transplant transfer device |
| CN214102935U (en) * | 2020-12-04 | 2021-09-03 | 上海长征医院 | Incubator for organ preservation |
-
2020
- 2020-12-04 CN CN202011410772.4A patent/CN112400866A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20140017664A1 (en) * | 2012-07-10 | 2014-01-16 | Lifeline Scientific, Inc. | Temperature sensing in organ preservation apparatus |
| CN205431770U (en) * | 2015-12-25 | 2016-08-10 | 深圳市第二人民医院 | Pancreas transplantation is with active fresh -keeping case |
| CN207355343U (en) * | 2017-09-29 | 2018-05-15 | 韩彤霞 | A kind of human organ transplant donor stores carrying device |
| CN110342104A (en) * | 2019-07-17 | 2019-10-18 | 蒋欣 | A kind of active shock insulation organ transplant transfer device |
| CN214102935U (en) * | 2020-12-04 | 2021-09-03 | 上海长征医院 | Incubator for organ preservation |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113317311A (en) * | 2021-05-17 | 2021-08-31 | 上海理工大学 | Preservation and transportation device for isolated organs |
| EP4344542A1 (en) * | 2022-09-30 | 2024-04-03 | Aferetica S.r.l. | Device for the storage and transport of biological material |
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