CN112386811B - Cooling type photodynamic therapy apparatus for intracavity therapy - Google Patents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0613—Apparatus adapted for a specific treatment
- A61N5/0625—Warming the body, e.g. hyperthermia treatment
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0613—Apparatus adapted for a specific treatment
- A61N5/062—Photodynamic therapy, i.e. excitation of an agent
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
- F25D17/00—Arrangements for circulating cooling fluids; Arrangements for circulating gas, e.g. air, within refrigerated spaces
- F25D17/02—Arrangements for circulating cooling fluids; Arrangements for circulating gas, e.g. air, within refrigerated spaces for circulating liquids, e.g. brine
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
- F25D29/00—Arrangement or mounting of control or safety devices
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
- F25D31/00—Other cooling or freezing apparatus
- F25D31/005—Combined cooling and heating devices
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- G—PHYSICS
- G05—CONTROLLING; REGULATING
- G05D—SYSTEMS FOR CONTROLLING OR REGULATING NON-ELECTRIC VARIABLES
- G05D23/00—Control of temperature
- G05D23/19—Control of temperature characterised by the use of electric means
- G05D23/1919—Control of temperature characterised by the use of electric means characterised by the type of controller
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61N5/00—Radiation therapy
- A61N2005/002—Cooling systems
- A61N2005/005—Cooling systems for cooling the radiator
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/0626—Monitoring, verifying, controlling systems and methods
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/063—Radiation therapy using light comprising light transmitting means, e.g. optical fibres
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Abstract
The invention provides a cooling type photodynamic therapy apparatus for intracavity therapy, which comprises a photodynamic therapy head PID temperature regulating system and a therapy head connector socket used for connecting a therapy head, wherein the therapy head connector socket is connected with a light source energy control panel and a PID temperature regulation control panel in the therapy apparatus, the therapy head connector socket is connected with a host end therapy head connector outside the therapy apparatus, the host end therapy head connector is connected with a therapy end therapy head connector through a connecting pipe, and the therapy end therapy head connector is connected with the therapy head. The invention can accurately set and control the treatment temperature in the cavity during photodynamic therapy, thoroughly avoids and eliminates 'photothermal effect' generated during photodynamic therapy, and provides guarantee for expanding the treatment application of the photodynamic therapy on the mucosa tissue of the inner cavity of the human body.
Description
Technical Field
The invention relates to a medical instrument for photodynamic therapy, in particular to a cooling type intracavity therapy treatment head technology which adopts the modern refrigeration technology to set temperature and control constant temperature and a photodynamic therapy system used for intracavity mucosal tissues.
Background
The progress of modern science and technology continuously pushes the progress and development of medical science. The development and popularization of modern photodynamic medicine provide safer, effective and convenient treatment means for the treatment of certain traditional diseases, and open up a new treatment way for diseases which can not be treated by the traditional medical treatment method.
In recent years, the use of photodynamic therapy has been widely used not only for the treatment of some body surface diseases, but also for the treatment of malignant tumors. For example: the traditional Chinese medicine composition has obvious curative effect on malignant tumors such as skin squamous cell carcinoma, oral squamous cell carcinoma, basal cell carcinoma, gynecological cervical early-stage precancerous lesion and the like, and is consistently determined and regarded as important by the medical field.
The basic principle of photodynamic therapy is: a specific photosensitizer, which generates a photochemical reaction in biological tissue in cooperation with irradiation of a specific wavelength spectrum, is composed of oxygen, a photosensitizer, and visible light (usually laser light) as essential elements. Firstly, the tumor tissue selectively takes up the photosensitizer and stores the photosensitizer therein, and then the photosensitizer is activated after local irradiation of light with proper wavelength to generate a photosensitizing effect. The photosensitizer is a porphyrin molecule capable of absorbing and re-releasing special wavelength and has a tetrapyrrole group structure. The first generation photosensitizers were hematoporphyrin derivatives (HpD), diphaemoporphyrin esters (DHE). Because tumor cells have more LDL receptors than normal cells, photosensitizers are more accessible into tumor cells mediated by LDL receptors; porphyrins can passively diffuse into cells, and the efficiency of diffusion is related to extracellular pH, with lower pH values dispersing more. The metabolism of tumor tissue is accelerated, so that the extracellular pH value is lower than that of normal tissue, and more porphyrins enter tumor cells. Therefore, the photosensitizer can quickly form singlet oxygen under the action of a specific spectrum, and pathological tissues and tumor cells are quickly poisoned and killed under the environment to achieve the purpose of curing diseases.
In the process of photodynamic therapy, the combination of light and photosensitizer can generate larger heat in the process of irradiation therapy, and stronger 'photothermal effect' is formed in human tissues, and the accumulation of photothermal effect can form 'thermal injury' on the treatment part if heat dissipation treatment is not carried out. Generally, the photodynamic therapy of the body surface can be implemented by cooling with cold air and spraying a coolant, but cooling is a problem to be solved when performing photodynamic therapy on some organs in cavities, and particularly when performing photodynamic therapy on delicate mucosal tissues such as vagina, cervix, oral cavity, anus and the like, if effective cooling is not performed, thermal damage of the mucosal tissues is very easily caused, so that the effective prevention of photothermal damage of the mucosal tissues in the process of photodynamic therapy on the inner cavities of a human body is a technical problem to be solved.
I have been engaged in the research work of photodynamic therapy at home from 1993, and have invented and adopted the semiconductor narrow spectrum technology for human disease treatment and photodynamic therapy, and obtained three invention patents and a plurality of utility model patents in this field, along with the progress of biomedical technology, numerous photosensitizers are continuously researched and developed, and photodynamic medicine is also continuously advanced and developed, and photodynamic therapy is gradually popularized and applied from common diseases to malignant tumors from the body surface to the body. Photodynamic medicine is the combined use of light and a photosensitizer, both of which are not indispensable. Therefore, the technical progress of the photodynamic therapy apparatus is also very important, and in order to solve the bottleneck problem of 'photo-thermal damage' of the inner cavity mucosa tissue in the photodynamic therapy, a set of photodynamic therapy system is developed, which can effectively protect the inner cavity mucosa tissue and is safe and reliable.
Disclosure of Invention
The invention aims to provide a cooling type photodynamic therapy apparatus for intracavity therapy, which thoroughly avoids and eliminates 'photothermal effect' generated during photodynamic therapy, and provides guarantee for expanding the therapeutic application of photodynamic on mucosal tissues of human body.
The technical scheme of the invention is as follows:
the utility model provides a cooled photodynamic therapy apparatus for intracavity treatment, includes treatment head PID temperature control system, keeps apart warm probe and light energy detection probe including installing the photoelectricity in the treatment head, the photoelectricity keeps apart the temperature and examines probe connection to PID temperature adjustment control panel, light energy detection probe is connected to light source energy control panel, light source energy control panel and PID temperature adjustment control panel are connected to CPU core control panel, the treatment head still connects the coolant liquid bin, and the two-cycle coolant liquid refrigerating system is connected to the coolant liquid bin, the two-cycle coolant liquid refrigerating system connects the coolant liquid circulating pump, the coolant liquid circulating pump is connected to the coolant liquid filter, thereby the coolant liquid filter is connected to the cyclic utilization of treatment head realization coolant liquid. The therapy apparatus also comprises a therapy head connector socket used for connecting the therapy head, the therapy head connector socket is connected with a light source energy control panel and a PID temperature adjusting control panel in the therapy apparatus, the therapeutic head connector socket is connected with a host end therapeutic head connector outside the therapeutic machine, the host end therapeutic head connector is connected with a therapeutic end therapeutic head connector through a connecting pipe, the therapeutic end therapeutic head connector is connected with a therapeutic head, the treatment head comprises a semiconductor narrow-spectrum light emitting array formed by a semiconductor narrow-spectrum light emitting unit surrounding the outer side wall of the cooling cavity, a transparent therapeutic head shell is arranged at the outer side of the semiconductor narrow-spectrum light emitting array, a cooling liquid inlet pipe and a cooling liquid outlet pipe are arranged in the cooling cavity, the cooling liquid inlet pipe, the cooling liquid outlet pipe, the cooling cavity and the treatment head shell form a treatment part inserted into the inner cavity of the human body.
The CPU core control panel is connected to the display and the control panel, and the light source energy control panel, the PID temperature adjustment control panel, the CPU core control panel, the double-circulation cooling liquid refrigeration system, the cooling liquid circulating pump, the display and the control panel are all connected to the power supply system.
And a cooling liquid flow photoelectric detector is also connected between the cooling liquid filter and the treatment head and is connected to the CPU core control board.
And a cooling liquid photoelectric isolation temperature detection probe is arranged in the cooling liquid storage tank and is connected to the PID temperature adjustment control panel.
The therapeutic machine is used for installing a radiating fan used for radiating the cavity on the shell of the cavity of the light source energy control panel and the PID temperature adjustment control panel, and the therapeutic machine is also provided with a therapeutic head placing frame used for supporting the therapeutic head.
The treatment head is provided with a light source working electrode socket and a signal detection electrode socket;
the semiconductor narrow-spectrum light-emitting array is connected with a light source working electrode socket, and the light source working electrode socket is connected with a light source energy control board;
the photoelectric isolation temperature detection probe and the light energy detection probe are connected to the PID temperature adjustment control panel and the light source energy control panel through the signal detection electrode socket and the therapeutic head connector socket.
The cooling cavity is of a cylindrical structure with one open end and one closed end, and the closed end of the cooling cavity is in a circular arc design.
A liquid inlet of the cooling liquid inlet pipe is connected to the cooling liquid filter, a liquid outlet of the cooling liquid inlet pipe extends to the closed end of the cooling cavity to convey cooling liquid into the whole cooling cavity, a liquid inlet of the cooling liquid outlet pipe is arranged at the closed end of the cooling cavity, and a liquid outlet of the cooling liquid outlet pipe is connected to the cooling liquid storage box to completely discharge the cooling liquid in the cooling cavity; the cross-sectional area of the cooling liquid inlet pipe is larger than that of the cooling liquid outlet pipe.
Compared with the prior art, the invention has the beneficial effects that: the modern control technology is adopted, an embedded computer system is taken as a core, and the technologies such as closed-loop light current detection, a photoelectric isolation type temperature detector, a double-circulation liquid refrigeration technology, a PID temperature control technology, an energy constant flow control technology and the like are integrated into a whole to form a complete therapeutic instrument system, so that the therapeutic temperature in the cavity during photodynamic therapy can be accurately set and controlled, the 'photothermal effect' generated during photodynamic therapy is thoroughly avoided and eliminated, the thermal injury to the mucosa tissue of the inner cavity of a human body is avoided, and the guarantee is provided for expanding the therapeutic application of the photodynamic on the mucosa tissue of the inner cavity of the human body.
Drawings
Fig. 1 is a schematic view of the overall structure of the therapy apparatus of the present invention.
Fig. 2 is a schematic cross-sectional structure of the therapeutic apparatus of the present invention.
Fig. 3 is a schematic diagram of the PID temperature regulation system of the photodynamic therapy head of the invention.
Fig. 4 is a schematic view of the treatment head connection of the present invention.
Fig. 5 is a schematic cross-sectional structure of the treatment head of the present invention.
Fig. 6 is a schematic sectional structure view of the treatment head of the present invention.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
As shown in fig. 3, a PID temperature adjusting system for a therapy head comprises a photoelectric isolation temperature detecting probe 17 and a light energy detecting probe 18 which are installed in the therapy head 1, wherein the photoelectric isolation temperature detecting probe 17 is connected to a PID temperature adjusting control board 21, the light energy detecting probe 18 is connected to a light source energy control board 20, the light source energy control board 20 and the PID temperature adjusting control board 21 are connected to a CPU core control board 22, the therapy head 1 is further connected to a cooling liquid storage tank 27, the cooling liquid storage tank 27 is connected to a dual-cycle cooling liquid refrigerating system 26, the dual-cycle cooling liquid refrigerating system 26 is connected to a cooling liquid circulating pump 25, the cooling liquid circulating pump 25 is connected to a cooling liquid filter 24, and the cooling liquid filter 24 is connected to the therapy head 1 so as to realize the recycling of cooling liquid.
The CPU core control board 22 is connected to a display and control panel 28, and the light source energy control board 20, the PID temperature adjustment control board 21, the CPU core control board 22, the dual-cycle coolant refrigeration system 26, the coolant circulation pump 25, and the display and control panel 28 are connected to a power supply system 29.
A cooling liquid flow photoelectric detector 23 is also connected between the cooling liquid filter 24 and the treatment head 1, and the cooling liquid flow photoelectric detector 23 is connected to the CPU core control board 22.
A coolant photoelectric isolation temperature detection probe 30 is arranged in the coolant storage tank 27, and the coolant photoelectric isolation temperature detection probe 30 is connected to the PID temperature adjustment control board 21.
As shown in fig. 1-4, a cooling type photodynamic therapy apparatus for intracavity therapy comprises the above-mentioned photodynamic therapy head PID temperature regulating system, and the light source energy control panel 20, PID temperature regulating control panel 21, CPU core control panel 22, coolant flow rate photodetector 23, coolant filter 24, coolant circulating pump 25, dual-circulating coolant refrigerating system 26, coolant storage tank 27, display and control panel 28 and power supply system 29 which constitute the photodynamic therapy head PID temperature regulating system are all installed in the casing of the therapy apparatus, the therapy apparatus further comprises a therapy head connector socket 31 for connecting the therapy head 1, the therapy head connector socket 31 is connected with the light source energy control panel 20 and the PID temperature regulating control panel 21 inside the therapy apparatus, the therapy head connector socket 31 is connected with a host end therapy head connector 32 outside the therapy apparatus, the main machine end treatment head connector 32 is connected to the treatment end treatment head connector 34 through a connecting pipe 33, and the treatment end treatment head connector 34 is connected with the treatment head 1.
The therapeutic machine is used for installing the radiating fan 35 used for radiating the cavity on the shell of the cavity of the light source energy control panel 20 and the PID temperature adjustment control panel 21, and the therapeutic machine is further provided with a therapeutic head placing frame 3 used for supporting the therapeutic head 1.
As shown in fig. 5 and 6, the treatment head 1 includes a semiconductor narrow-spectrum light emitting array formed by a semiconductor narrow-spectrum light emitting unit 10 surrounding the outer side wall of a cooling cavity 11, a transparent treatment head housing 12 is arranged outside the semiconductor narrow-spectrum light emitting array, a cooling liquid inlet pipe 15 and a cooling liquid outlet pipe 16 are installed in the cooling cavity 11, and the cooling liquid inlet pipe 15, the cooling liquid outlet pipe 16, the cooling cavity 11 and the treatment head housing 12 constitute a treatment portion inserted into the inner cavity of the human body.
The treatment head 1 is provided with a light source working electrode socket 14 and a signal detection electrode socket 13;
the semiconductor narrow-spectrum light emitting array is connected with a light source working electrode socket 14, and the light source working electrode socket 14 is connected with a light source energy control board 20;
the photoelectric isolation temperature detection probe 17 and the light energy detection probe 18 are connected to the PID temperature adjustment control board 21 and the light source energy control board 20 through the signal detection electrode socket 13 and the treatment head connector socket 31.
The cooling cavity 11 is a cylinder structure with an opening at one end and a closed end, and the closed end of the cooling cavity 11 is in a circular arc shape.
A liquid inlet of the cooling liquid inlet pipe 15 is connected to the cooling liquid filter 24, a liquid outlet of the cooling liquid inlet pipe 15 extends to the closed end of the cooling cavity 11 to convey cooling liquid into the whole cooling cavity 11, a liquid inlet of the cooling liquid outlet pipe 16 is arranged at the closed end of the cooling cavity 11, and a liquid outlet of the cooling liquid outlet pipe 16 is connected to the cooling liquid storage tank 27 to completely discharge the cooling liquid in the cooling cavity 11; the cross-sectional area of the coolant inlet pipe 15 is larger than that of the coolant outlet pipe 16.
The treatment head 1 is a temperature-adjustable constant-temperature cooling type photodynamic treatment head for intracavity treatment, and modern semiconductor narrow-spectrum light emitting devices with different wavelengths of 400nm-800nm can be adopted as treatment light sources according to treatment requirements; in order to adapt to the characteristics of photodynamic therapy of a human body inner cavity, the treatment part of the treatment head is designed into a luminous body with a cylindrical structure; the semiconductor narrow-spectrum light-emitting device takes a flexible circuit board as a substrate, and a printed circuit board is designed according to the electrical parameters of the semiconductor narrow-spectrum light-emitting device; and welding the semiconductor narrow-spectrum light-emitting device on a flexible circuit board to form a bendable light source circuit part.
The cooling cavity 11 is a closed cylindrical therapeutic head radiator body which is made of metal heat conducting materials, has a hollow interior and a smooth exterior according to the size of the cylindrical therapeutic head; one end of the cylindrical radiator body is provided with two cold junction interfaces which are connected with a refrigerant circulating pipe.
The cooling mode of the therapeutic head adopts the forced cooling of the temperature-controllable refrigerating fluid; inside the treatment head, a cooling liquid single-tube forced conveying mode is invented, the cooling flow channel is of a 'differential flow channel' structure, namely, an inlet of the cooling liquid is conveyed to the top end of the treatment head by a single tube in a forced flow guiding mode and flows out, then the cooling liquid is filled in the whole cooling cavity and flows back to the liquid return tube, and the 'differential flow channel' conveying is formed because the sectional area of the conveying tube is larger than that of the cooling cavity in the treatment head, so that no dead angle exists in the cooling cavity of the treatment head, and no bubble flows to maximize the cooling efficiency.
The electrode wire signal detection line of the treatment head and the like are led out by adopting a connector, so that the treatment head is conveniently connected with a treatment machine; the coolant liquid conveyer pipe adopts the soft resistant high microthermal combined material to make to at the high-efficient insulation material of pipe surface parcel with prevent that the temperature from giving off and causing the energy extravagant and temperature control inaccurate, with coolant liquid conveyer pipe, working electrode, detection electrode integration for a connecting pipe, adopt water and electricity separation plug to connect therapy apparatus and treatment head respectively, the plug can be wantonly drawn to treatment head one end, is convenient for change the treatment head of different wavelength and different specifications.
The light energy detection probe monitors the luminous intensity of the semiconductor narrow-spectrum luminous array in real time and transmits the luminous intensity to the light source energy control panel, the light source energy control panel controls the luminous intensity of the semiconductor narrow-spectrum luminous array, and the intensity of light is adjusted according to different requirements, so that the accuracy of treatment is ensured. The high-precision micro embedded temperature detector is adopted, the probe is directly embedded in the capsule wall at the central part of the treatment head cooling cavity, the temperature change of the treatment head is uniformly detected, and a temperature signal led out by an electrode of the temperature detector is convenient for a computer to carry out temperature regulation and constant temperature control. The PID temperature adjustment control board can carry out the regulation control precision height of temperature through the flow and the velocity of flow of control coolant liquid according to the temperature numerical value that temperature detecting head 17 detected is kept apart to the photoelectricity, and the cooling effect is good, effectively avoids causing mucosa tissue thermal damage when carrying out inner chamber photodynamic therapy.
Furthermore, it should be understood that although the present description refers to embodiments, not every embodiment may contain only a single embodiment, and such description is for clarity only, and those skilled in the art should integrate the description, and the embodiments may be combined as appropriate to form other embodiments understood by those skilled in the art.
Claims (8)
1. The utility model provides a cooled photodynamic therapy apparatus for intracavity therapy, which is characterized in that, including therapy head PID temperature control system, therapy head PID temperature control system is including installing photoelectricity isolation temperature detection probe (17) and light energy detection probe (18) in therapy head (1), photoelectricity isolation temperature detection probe (17) is connected to PID temperature control panel (21), light energy detection probe (18) are connected to light source energy control panel (20), light source energy control panel (20) and PID temperature control panel (21) are connected to CPU core control panel (22), therapy head (1) still connects coolant liquid storage tank (27), and double circulation coolant liquid refrigerating system (26) is connected to coolant liquid storage tank (27), double circulation coolant liquid refrigerating system (26) connect coolant liquid circulating pump (25), coolant liquid circulating pump (25) is connected to coolant liquid filter (24), the cooling liquid filter (24) is connected to the treatment head (1) so as to realize the recycling of the cooling liquid, the treatment machine further comprises a treatment head connector socket (31) used for connecting the treatment head (1), the treatment head connector socket (31) is connected with a light source energy control board (20) and a PID temperature adjustment control board (21) in the treatment machine, the treatment head connector socket (31) is connected with a host end treatment head connector (32) outside the treatment machine, the host end treatment head connector (32) is connected to a treatment end treatment head connector (34) through a connecting pipe (33), the treatment end treatment head connector (34) is connected with the treatment head (1), the treatment head (1) comprises a semiconductor narrow spectrum light emitting array formed by a semiconductor narrow spectrum light emitting unit (10) surrounding the outer side wall of the cooling cavity (11), and a transparent treatment head shell (12) is arranged outside the semiconductor narrow spectrum light emitting array, install coolant liquid feed pipe (15) and coolant liquid drain pipe (16) in cooling cavity (11), coolant liquid feed pipe (15), coolant liquid drain pipe (16), cooling cavity (11) and treatment head shell (12) are constituteed and are inserted the treatment portion of human inner chamber.
2. The photodynamic therapy machine for cooled intracavity therapy according to claim 1, wherein said CPU core control board (22) is connected to a display and control panel (28), and said light source energy control board (20), PID temperature adjustment control board (21), CPU core control board (22), dual-cycle coolant refrigeration system (26), coolant circulation pump (25) and display and control panel (28) are connected to a power supply system (29).
3. A photodynamic therapy machine for cooled intracavity therapy according to claim 1 wherein a coolant flow rate photodetector (23) is further connected between the coolant filter (24) and the therapy head (1), the coolant flow rate photodetector (23) being connected to the CPU core control board (22).
4. The photodynamic therapy machine for cooled intracavity therapy as recited in claim 1, wherein a coolant photo-electric isolation temperature detecting probe (30) is disposed in said coolant storage tank (27), and said coolant photo-electric isolation temperature detecting probe (30) is connected to a PID temperature adjustment control board (21).
5. The photodynamic therapy apparatus for cooling type intracavity therapy as claimed in claim 1, wherein a heat dissipation fan (35) for dissipating heat from the cavity is disposed on the housing of the cavity for mounting the light source energy control board (20) and the PID temperature adjustment control board (21), and a therapy head placing frame (3) for supporting the therapy head (1) is further disposed on the therapy apparatus.
6. Photodynamic therapy machine for cooled intracavity therapy according to claim 1, characterized in that said therapy head (1) is provided with a light source working electrode socket (14) and a signal detection electrode socket (13);
the semiconductor narrow-spectrum light emitting array is connected with a light source working electrode socket (14), and the light source working electrode socket (14) is connected with a light source energy control board (20);
the photoelectric isolation temperature detection probe (17) and the light energy detection probe (18) are connected to a PID temperature adjustment control board (21) and a light source energy control board (20) through a signal detection electrode socket (13) and a treatment head connector socket (31).
7. The photodynamic therapy machine for cooled intracavity therapy as recited in claim 1, wherein said cooling chamber (11) is a cylindrical structure with an open end and a closed end, and the closed end of the cooling chamber (11) is in the shape of a circular arc.
8. A cooled intracavity therapeutic photodynamic therapy device as claimed in claim 1 wherein, the inlet of said coolant inlet tube (15) is connected to a coolant filter (24), the outlet of said coolant inlet tube (15) extends to the closed end of the cooling chamber (11) for feeding coolant into the entire cooling chamber (11), the inlet of said coolant outlet tube (16) is disposed at the closed end of the cooling chamber (11), and the outlet of said coolant outlet tube (16) is connected to a coolant storage tank (27) for completely discharging the coolant from the cooling chamber (11); the cross-sectional area of the cooling liquid inlet pipe (15) is larger than that of the cooling liquid outlet pipe (16).
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| CN202110068983.2A CN112386811B (en) | 2021-01-19 | 2021-01-19 | Cooling type photodynamic therapy apparatus for intracavity therapy |
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| CN202110068983.2A CN112386811B (en) | 2021-01-19 | 2021-01-19 | Cooling type photodynamic therapy apparatus for intracavity therapy |
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| CN112386811B true CN112386811B (en) | 2021-04-09 |
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