CN112386252A - Blood glucose measuring probe and blood glucose measuring device and method - Google Patents
Blood glucose measuring probe and blood glucose measuring device and method Download PDFInfo
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- CN112386252A CN112386252A CN201910754311.XA CN201910754311A CN112386252A CN 112386252 A CN112386252 A CN 112386252A CN 201910754311 A CN201910754311 A CN 201910754311A CN 112386252 A CN112386252 A CN 112386252A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
Abstract
The invention discloses a blood sugar measuring probe, which comprises: the temperature sensor comprises a probe lower shell, a probe upper shell, a torsion spring, a finger containing assembly, a temperature sensor, a heat conducting rod, a first thermistor and a second thermistor which are respectively positioned at the upper end and the lower end of the heat conducting rod, a photoelectric receiver, a Light Emitting Diode (LED) and a humidity sensor. The blood sugar measured by the blood sugar measuring probe is more accurate.
Description
Technical Field
The invention relates to the technical field of blood sugar measurement, in particular to a blood sugar measuring probe, a blood sugar measuring device and a blood sugar measuring method.
Background
In the related art, there are many blood sugar monitoring methods, and among them, there are many non-invasive blood sugar detection methods, such as infrared spectroscopy, raman spectroscopy, etc. These methods have problems that the blood glucose concentration in human blood is low and that the measurement of the blood glucose concentration is greatly disturbed by other substances.
One of the noninvasive blood glucose measurement methods is metabolic heat integration, which measures blood glucose by measuring parameters related to human metabolism. Cho OK published in 2004 a document Cho, O.K., et al (2004), "Noninvasive measurement of glucose by metabolic fat formation method" Clinical Chemistry 50(10): 1894-.
In addition, US2006/0094941 discloses a blood glucose testing device and method based on thermal and optical sensors. The structure of the device is shown in fig. 1 and fig. 2, wherein 21 is a flat plate or a thin plate with good thermal conductivity, 22 is a thermal conduction device, 23 and 24 are thermistors, 33 is an optical fiber, 31a, 31b, 31c and 31d of 31 are optical fibers, 36a, 36b and 36c of 36 are LEDs, 38 is a photoelectric sensor or a light receiver, 40 is a photodiode (light receiver), and 25, 26, 27 and 28 are radiation temperature sensors. A finger is placed above the device in contact with the flat or thin plate 21. The radiation temperature sensor tests the temperature of the finger; the light receiver tests the light intensity of light emitted by the LED after passing through the finger, and is used for testing the concentration of hemoglobin and the degree of blood oxygen saturation; the thermistors at the two ends of the heat conducting rod change along with the temperature. The blood glucose monitoring device and method of US2006/0094941 have problems: 1. the heat emitted by the human body through the evaporation route is not considered; 2. when in test, a small area behind the finger is contacted with the device, other parts are exposed outside, and the movement of the finger can bring great interference to the test.
In summary, the problems of the current noninvasive blood glucose monitoring methods are mainly as follows: the content of blood sugar in blood is very low, substances with high content such as hemoglobin and water bring great interference to a non-invasive blood sugar test, and the blood sugar measured by the existing blood sugar measuring device and method is not accurate enough.
Disclosure of Invention
In order to solve the above technical problems, the present invention provides a blood glucose measuring probe, a blood glucose measuring device and a blood glucose measuring method, which can improve the accuracy of blood glucose measurement.
In order to achieve the object of the present invention, the present invention provides a blood glucose measuring probe comprising: the device comprises a probe lower shell, a probe upper shell, a torsion spring, a finger containing assembly, a temperature sensor, a heat conducting rod, a first thermistor and a second thermistor which are respectively positioned at the upper end and the lower end of the heat conducting rod, a photoelectric receiver, a Light Emitting Diode (LED) and a humidity sensor;
the lower probe shell is connected with the upper probe shell through the torsion spring and a connecting shaft positioned in the center of the torsion spring, the lower probe shell and the upper probe shell are connected with the finger containing assembly, one end of the torsion spring is in contact connection or fixed connection with the lower probe shell, and the other end of the torsion spring is in fixed connection or contact connection with the upper probe shell;
the temperature sensor is configured to: measuring the ambient temperature and the finger temperature;
the finger-receiving assembly is configured to: accommodating a finger;
the heat conducting rod is arranged vertically or approximately vertically to the finger containing assembly and is arranged to: transferring finger heat to the first and second thermistors;
the LED and the photoelectric receiver are respectively positioned on the upper side and the lower side of the finger containing component and are oppositely arranged, and the LED is arranged as follows: emitting light; the photoelectric receiver is arranged to: receiving light left after the light emitted by the LED passes through the finger;
the humidity sensor is configured to: ambient humidity and finger humidity were measured.
Optionally, the blood glucose measuring probe further comprises a probe connection wire, wherein,
the temperature sensor, the first thermistor, the second thermistor, the photoelectric receiver, the LED and the humidity sensor are all electrically connected with the probe connecting wire through a connector on a bottom plate of the blood glucose measuring probe;
the probe connecting wire is electrically connected with the power supply and the processor.
Optionally, the blood glucose measuring probe further comprises a grommet press block configured to: and connecting the probe connecting wire with the connector and then sealing the probe connecting wire.
Optionally, the blood glucose measurement probe further comprises: a heat sink sheet, wherein,
the heat sink is configured to: after the finger is put into the blood sugar measuring probe, the finger is separated from the heat conducting rod, and after the finger is taken out of the blood sugar measuring probe, the finger is contacted with the heat conducting rod to radiate heat for the heat conducting rod.
Optionally, the blood glucose measuring probe further comprises a heat conducting rod support member, one end of the heat conducting rod support member is fixed on the heat sink, and is configured to: supporting the heat conducting rod.
Optionally, the heat conducting rod support is fixed on the heat sink by a snap.
Optionally, the finger accommodation assembly comprises an upper silica gel pad and a lower silica gel pad, the upper silica gel pad is fixed to the upper probe shell through an upper silica gel pad pasting plate, and the lower silica gel pad is fixed to the lower probe shell through a lower silica gel pad pasting plate.
Optionally, the blood glucose measuring probe further comprises a spring plate and a compression spring, wherein,
one end of the elastic sheet is fixedly connected with the upper silica gel pad pasting plate, and the other end of the elastic sheet is fixedly connected with the probe upper shell;
the compression spring is positioned in the heat conducting rod supporting piece, one end of the compression spring is abutted against the heat conducting rod supporting piece, the other end of the compression spring is abutted against the heat conducting rod, and the compression spring enables the heat conducting rod to be in close contact with the radiating fin.
Optionally, one end of the heat sink is fixedly connected with the other end of the heat conducting rod supporting piece, the other end of the heat sink is fixedly connected with the lower silica gel pad pasting plate, and the lower silica gel pad pasting plate is fixedly connected with the lower probe shell;
the heat conduction rod protrudes out of the surface of the lower silica gel pad before fingers are placed into the finger accommodating assembly, the fingers move downwards after being placed into the finger accommodating assembly due to being pressed, and the compression spring provides force required by close contact between the heat conduction rod and the fingers.
Optionally, the temperature sensor is an infrared radiation temperature sensor, and is further configured to: sending its measured temperature to the processor.
Optionally, the first thermistor and the second thermistor are further configured to send the respective measured heat to the processor, so that the processor measures the blood flow rate of the human body according to the temperature change.
Optionally, the LED is a 4-band LED, and the LED sequentially emits light of 660nm, 730nm, 805nm, and 940 nm.
Optionally, the humidity sensor is further configured to: and sending the measured environment humidity and the measured finger humidity to the processor, so that the processor can calculate the heat dissipated by the human body through evaporation according to the environment humidity and the finger humidity.
The invention also discloses a blood sugar measuring device, which comprises the blood sugar measuring probe and a processor, wherein the processor is electrically connected with the probe connecting wire of the blood sugar measuring probe and is arranged as follows: and receiving various signals sent by the blood sugar measuring probe, and measuring the blood sugar of the human body according to the various signals received from the blood sugar measuring probe.
Compared with the prior art, the invention comprises the following steps: a blood glucose measurement probe, comprising: the device comprises a probe lower shell, a probe upper shell, a torsion spring, a finger containing assembly, a temperature sensor, a heat conducting rod, a first thermistor and a second thermistor which are respectively positioned at the upper end and the lower end of the heat conducting rod, a photoelectric receiver, a Light Emitting Diode (LED) and a humidity sensor; the lower probe shell is connected with the upper probe shell through the torsion spring and a connecting shaft positioned in the center of the torsion spring, the lower probe shell and the upper probe shell are connected with the finger containing assembly, one end of the torsion spring is in contact connection or fixed connection with the lower probe shell, and the other end of the torsion spring is in fixed connection or contact connection with the upper probe shell; the temperature sensor is configured to: measuring the ambient temperature and the finger temperature; the finger-receiving assembly is configured to: accommodating a finger; the heat conducting rod is arranged vertically or approximately vertically to the finger containing assembly and is arranged to: transferring finger heat to the first and second thermistors; the LED and the photoelectric receiver are respectively positioned on the upper side and the lower side of the finger containing component and are oppositely arranged, and the LED is arranged as follows: emitting light; the photoelectric receiver is arranged to: receiving light left after the light emitted by the LED passes through the finger; the humidity sensor is configured to: the blood sugar measuring accuracy can be improved by measuring the environmental humidity and the finger humidity.
Furthermore, the embodiment of the invention tests the environmental humidity and the humidity of the skin surface of the human body by adding the humidity sensor, further calculates the heat dissipation of the human body through an evaporation way, and improves the accuracy of the non-invasive blood sugar test.
According to the embodiment of the invention, the finger clip type probe is designed, so that the finger is completely wrapped by the probe during testing, the stability of the testing process is ensured, and the measured blood sugar is more accurate.
The integral structure of the probe provided by the embodiment of the invention can adapt to fingers with different thicknesses.
The probe provided by the embodiment of the invention has a simple structure, parts are convenient to process and produce, and the assembly and disassembly are easy; the upper part of the finger containing component is of an elastic cantilever structure, one end of the finger containing component sinks, the elastic design can counteract the pressure of a finger on a device at the lower part of the finger containing component, the deformation of blood vessels caused by the pressure of the finger is avoided, the force of the finger among the torsion spring, the elastic sheet and the compression spring is ensured to be balanced, so that the finger containing component is suitable for fingers with different sizes, the fingers with different sizes are ensured to have relatively balanced pressure in the probe, and the influence of the finger pressure on data acquisition can be effectively eliminated; the heat conduction stick elastic fixing piece is a cylindrical compression spring structure, so that the heat conduction stick is only vertical to the finger in the movement of separating from the radiating fin after contacting with the finger, the heat conduction stick can be well attached to the finger, the influence on data acquisition caused by floating of the heat conduction stick can be effectively eliminated, and the consistency of accurately acquiring physiological data at each time is ensured.
Additional features and advantages of the invention will be set forth in the description which follows, and in part will be obvious from the description, or may be learned by practice of the invention. The objectives and other advantages of the invention will be realized and attained by the structure particularly pointed out in the written description and claims hereof as well as the appended drawings.
Drawings
The accompanying drawings are included to provide a further understanding of the invention and are incorporated in and constitute a part of this specification, illustrate embodiments of the invention and together with the example serve to explain the principles of the invention and not to limit the invention.
FIG. 1 is a view showing one of the structures of a conventional blood sugar measuring apparatus;
FIG. 2 is a second structural view of a conventional blood glucose measuring device;
FIG. 3 is a schematic structural view of a blood glucose measurement probe according to an embodiment of the present invention;
FIG. 4 is a schematic cross-sectional A-A structure of FIG. 3 according to an embodiment of the present invention;
FIG. 5 is a schematic structural diagram of a spring plate according to an embodiment of the present invention;
FIG. 6 is a schematic view of a connection structure of a heat conducting rod, a heat sink, a heat conducting rod supporting member and a compression spring according to an embodiment of the present invention;
fig. 7 is a schematic view of a connection structure of the upper shell of the probe, the upper contact pad pasting plate and the elastic sheet according to the embodiment of the invention.
Description of reference numerals:
1-a lower probe shell, 2-a wire sheath pressing block, 3-a probe connecting wire, 4-an upper probe shell, 5-a temperature sensor, 6-a spring plate, 7-a heat conducting rod, 8-a thermistor, 9-a photoelectric receiver, 10-an LED, 11-a torsion spring, 12-a lower silica gel pad pasting plate, 13-a lower contact pad, 14-an upper silica gel pad pasting plate, 15-an upper contact pad, 16-a humidity sensor, 17-a heat radiating fin, 18-a heat conducting rod supporting piece, 19-a compression spring, 20-a finger containing component and 21-a connecting shaft.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, embodiments of the present invention will be described in detail below with reference to the accompanying drawings. It should be noted that the embodiments and features of the embodiments in the present application may be arbitrarily combined with each other without conflict.
The present invention discloses a blood sugar measuring probe, as shown in fig. 3 and 4, comprising: the probe comprises a probe lower shell 1, a probe upper shell 4, a probe connecting wire 3, a finger containing component 20, a temperature sensor 5, a heat conducting rod 7, a first thermistor 8 and a second thermistor 8' which are respectively positioned at the upper end and the lower end of the heat conducting rod, a photoelectric receiver 9, a Light Emitting Diode (LED) lighting Diode, an LED10, a humidity sensor 16, a radiating fin 17 and a heat conducting rod supporting piece 18.
The lower probe shell 1 is connected with the upper probe shell 4 through a torsion spring 11 and a connecting shaft 21; probe inferior valve 1 and probe epitheca 4 hold the subassembly 20 with the finger through screw or other modes and be connected, and wherein, torsion spring 11's one end and probe inferior valve 1 contact are connected or fixed connection, and torsion spring 11's the other end and probe epitheca 4 fixed connection or contact are connected. The contact connection refers to abutting against the lower probe shell 1 or the upper probe shell 4 by means of elastic force, specifically, one end of the torsion spring 11 with two support legs is installed and fixed on the upper probe shell 4, and the other end of the torsion spring 11 abuts against the lower probe shell 1 by means of elastic force; or one end of the torsion spring 11 with two supporting legs is fixedly arranged on the lower probe shell 1, and the other end of the torsion spring 11 is propped against the upper probe shell 4 by virtue of elasticity; or, both ends of the torsion spring 11 are propped against the upper shell 4 and the lower shell 1 of the probe by means of elastic force; alternatively, both ends of the torsion spring 11 are fixedly connected to the probe upper shell 4 and the probe lower shell 1.
The temperature sensor 5 is located above or below the finger-receiving member 20, generally below the finger-receiving member 20, and is used for measuring the temperature of the finger, and may or may not be in contact with the finger. The temperature sensor 5 may be an infrared radiation temperature sensor, and when the temperature sensor 5 is an infrared radiation temperature sensor, the radiation temperature of the skin is measured by an infrared radiation signal without contacting with a finger. The temperature sensor 5 may send its measured temperature to a processor connected to the blood glucose measurement probe.
The heat conduction rod 7 is positioned above or below the finger-receiving member 20, is generally positioned below the finger-receiving member 20, is arranged vertically or approximately vertically to the finger-receiving member 20, and is used for contacting with a finger and transferring finger heat to the first thermistor 8 and the second thermistor 8 ', and the first thermistor 8 and the second thermistor 8 ' transmit the respective measured heat to the processor connected to the blood glucose measuring probe, so that the processor measures the blood flow rate of the human body according to the temperature changes of the thermistors 8 and 8 ' positioned at the upper and lower ends of the heat conduction rod 7.
The LED10 and the photoelectric receiver 9 are respectively located at the upper and lower sides of the finger-holding member 20, the LED10 is used for emitting light of a specific wavelength, the light passes through the finger, and the rest of the light is received by the photoelectric receiver 9. Because of the fluctuation of the human body pulse, the intensity of light received by the photoelectric receiver 9 through the finger is strong and weak, and the pulse, the blood oxygen saturation and the hemoglobin of the human body can be measured by the intensity of light received by the photoelectric receiver 9. Optionally, the LED10 is a 4-band LED. The LED10 sends the light signal it sends to a processor connected to the blood glucose measuring probe, and the photoreceiver 9 also sends the light signal it receives to the processor. The LED10 may emit light at any one or more of 660nm, 730nm, 805nm, and 940 nm. Optionally, the LEDs 10 sequentially emit lights of 660nm, 730nm, 805nm and 940nm, and the calculation is performed through comprehensive information of 4 wavelengths to obtain the blood oxygen saturation, the pulse and the hemoglobin, or the blood sugar is directly calculated through light intensity information.
The humidity sensor 16 is located above or below the finger containing component 20, generally located below the finger containing component 20, and is configured to measure ambient humidity and finger humidity, and send the ambient humidity and the measured finger humidity to the processor connected to the blood glucose measuring probe, so that the processor can calculate the heat dissipated by the human body according to the ambient humidity and the finger humidity. Optionally, the humidity sensor is not in contact with the finger, and after the finger is placed in the probe, the humidity sensor 16, the lower contact pad and the finger form a semi-closed space, so that the humidity of the finger can be measured.
The heat radiating fins 17 are separated from the heat conducting rod 7 after the fingers are put into the probe, and the fingers are in contact with the heat conducting rod 7 after being taken out, so that heat is radiated to the heat conducting rod 7, specifically, the residual heat of the heat conducting rod 7 after the test is finished once is radiated as soon as possible, the temperature of the heat conducting rod 7 is balanced with the ambient temperature as soon as possible, and the next test can be started.
One end of the heat conducting rod support member 18 is fixedly connected to one end of the heat sink 17 by a snap or other means, and is used for supporting the heat conducting rod 7.
The temperature sensor 5, the first thermistor 8 and the second thermistor 8' which are respectively positioned at the upper end and the lower end of the heat conducting rod, the photoelectric receiver 9, the LED10 and the humidity sensor 16 are electrically connected with the probe connecting wire 3 through connectors on the bottom plate of the probe. The probe connecting wire 3 can be positioned at any position of the probe, and the probe connecting wire 3 is positioned at the left side of the probe in the figure. The probe connecting wire 3 is electrically connected with a power supply and a processor. The probe connecting wire 3 is provided with a power wire and a data wire. The data line transmits analog signals and digital signals, the digital signals are directly connected with the processor, and the analog signals are connected with the processor after passing through the processing circuit. Optionally, there are 14 lines in the probe connection line.
In an exemplary embodiment, the blood sugar measuring probe further comprises a wire sheath pressing block 2 for connecting the probe connecting wire 3 with a connector on the bottom plate of the probe and then sealing the probe connecting wire 3, so as to fix the probe connecting wire 3 and play a role in decoration.
In an exemplary embodiment, the finger containment assembly 20 includes an upper contact pad 15 and a lower contact pad 13. The upper contact pad 15 and the lower contact pad 13 may be silica gel pads, and when the upper contact pad 15 and the lower contact pad 13 are silica gel pads, the upper contact pad 15 is fixed to the probe upper case 4 through the upper silica gel pad pasting plate 14, and the lower contact pad 13 is fixed to the probe lower case 4 through the lower silica gel pad pasting plate 12. Optionally, the lower contact pad 13 is M-shaped.
One end of the radiating fin 17 is fixedly connected with the other end of the heat conducting rod supporting piece 18 through a buckle or other modes, the other end of the radiating fin 17 is fixedly connected with the lower silica gel pad pasting plate 12 through a screw or other modes, and the lower silica gel pad pasting plate 12 is fixedly connected with the lower probe shell 1 through a screw or other modes.
The blood sugar measuring probe also comprises an elastic sheet 6 and a compression spring 19, as shown in fig. 7, one end of the elastic sheet 6 is connected with the upper silica gel pad pasting plate 14 through two screws or other modes, the other end of the elastic sheet is connected with the probe upper shell 4 through two screws or other modes, the upper silica gel pad assembly (comprising the upper silica gel pad pasting plate 14 and the upper contact pad 15) is installed on the probe upper shell 4 in a cantilever mode through the elastic sheet 6, and the elastic sheet 6 can be fixed on the probe lower shell 1 or the probe upper shell 4 through screws or other modes. The shape of the elastic sheet 6 is concave-like. The compression spring 19 may be a cylindrical compression spring, and one end of the compression spring 19 abuts against the lower end of the heat conducting rod 7, and the other end abuts against the heat conducting rod support member 18, so as to provide a force required for the close contact between the heat conducting rod 7 and the finger. The heat conduction rod 7 protrudes out of the surface of the lower contact pad 13 before a finger is put into the probe, the finger presses the heat conduction rod 7 after being put into the probe, the heat conduction rod 7 moves downwards, and the cylindrical compression spring 19 provides force required by close contact between the heat conduction rod 7 and the finger. The forces or interactions among the torsion spring 11, the spring 6 and the compression spring 19 are balanced so that the probe can accommodate fingers of different sizes.
One end of the heat conducting rod supporting piece 18 is fixed on the radiating fin 17 through a buckle or other modes, the compression spring 19 is arranged in the heat conducting rod supporting piece 18, one end of the compression spring is pressed against the heat conducting rod supporting piece 18, the other end of the compression spring is pressed against the heat conducting rod 7, the tension of the compression spring 19 enables the heat conducting rod 7 to be in close contact with the radiating fin 17, and the specific connection relationship can be seen in an attached figure 6.
The embodiment of the invention also discloses a blood sugar measuring method, which is applied to the blood sugar measuring probe, and the probe needs to be placed on a flat desktop during blood sugar testing. When the probe is used, one sides of the torsion springs 11 of the upper probe shell 4 and the lower probe shell 1 are pressed, one sides of the upper probe shell 4 and the lower probe shell 1, where the torsion springs 11 are located, are close to each other under the action of the torsion springs 11, the other sides of the upper probe shell 4 and the lower probe shell 1 are far away from each other or are opened, fingers can be placed into the opened sides, and the fingers are in close contact with the upper contact pad 15 and the lower contact pad 13 after being placed into the probe. When fingers with different thicknesses are inserted into the probe, the elastic sheet 6 can deform differently to drive the upper contact pad 15 and the LED10 to move, so that the probe is suitable for fingers with different thicknesses. The heat conducting rod 7 protrudes out of the surface of the lower contact pad 13 before the finger is put into the probe, and the heat conducting rod 7 moves downwards after the finger is put into the probe. The compression spring 19 provides the force required for the heat conducting rod 7 to come into close contact with the finger. The forces among the torsion spring 11, the elastic sheet 6 and the compression spring 19 are balanced, and the probe can be ensured to adapt to fingers with different sizes.
The invention also discloses a blood sugar measuring device, which comprises the blood sugar measuring probe and a processor, wherein the processor is electrically connected with the probe connecting wire of the blood sugar measuring probe, is used for receiving various signals sent by the blood sugar measuring probe and measuring the blood sugar of the human body according to the various signals received from the blood sugar measuring probe.
The non-invasive blood sugar measuring device calculates blood sugar by testing temperature, humidity, blood flow rate, blood oxygen saturation, hemoglobin and pulse related to human body metabolism. The sensor in the probe comprises: the device comprises an infrared radiation temperature sensor, a humidity sensor, a heat conduction rod, thermistors arranged at two ends of the heat conduction rod, a 4-waveband LED and a light receiver. The 4-waveband LED and the optical receiver are positioned on two sides of a finger, and the blood oxygen saturation, the hemoglobin and the pulse are tested by a transmission method. The wavelengths of the 4-band LEDs are 660nm, 730nm, 805nm, and 940nm, respectively. The infrared radiation temperature sensor is not in direct contact with the skin, and can measure the radiation temperature of the skin. The humidity sensor is used for measuring environment humidity and human skin humidity, and after the probe is put into to the finger, the silica gel pad forms airtight space with the finger, and the moisture on finger skin surface gathers in airtight space. The heat conducting rod and the thermistors at the two ends of the heat conducting rod are used for measuring the blood flow velocity.
The finger that realizes adapting to different thickness through the torsion spring of epitheca and the cylinder compression spring of heat conduction stick below to and the shell fragment of epitheca.
It will be understood by those of ordinary skill in the art that all or some of the steps of the methods, systems, functional modules/units in the devices disclosed above may be implemented as software, firmware, hardware, and suitable combinations thereof. In a hardware implementation, the division between functional modules/units mentioned in the above description does not necessarily correspond to the division of physical components; for example, one physical component may have multiple functions, or one function or step may be performed by several physical components in cooperation. Some or all of the components may be implemented as software executed by a processor, such as a digital signal processor or microprocessor, or as hardware, or as an integrated circuit, such as an application specific integrated circuit. Such software may be distributed on computer readable media, which may include computer storage media (or non-transitory media) and communication media (or transitory media). The term computer storage media includes volatile and nonvolatile, removable and non-removable media implemented in any method or technology for storage of information such as computer readable instructions, data structures, program modules or other data, as is well known to those of ordinary skill in the art. Computer storage media includes, but is not limited to, RAM, ROM, EEPROM, flash memory or other memory technology, CD-ROM, Digital Versatile Disks (DVD) or other optical disk storage, magnetic cassettes, magnetic tape, magnetic disk storage or other magnetic storage devices, or any other medium which can be used to store the desired information and which can accessed by a computer. In addition, communication media typically embodies computer readable instructions, data structures, program modules or other data in a modulated data signal such as a carrier wave or other transport mechanism and includes any information delivery media as known to those skilled in the art.
Claims (14)
1. A blood glucose measurement probe, comprising: the device comprises a probe lower shell, a probe upper shell, a torsion spring, a finger containing assembly, a temperature sensor, a heat conducting rod, a first thermistor and a second thermistor which are respectively positioned at the upper end and the lower end of the heat conducting rod, a photoelectric receiver, a Light Emitting Diode (LED) and a humidity sensor;
the lower probe shell is connected with the upper probe shell through the torsion spring and a connecting shaft positioned in the center of the torsion spring, the lower probe shell and the upper probe shell are connected with the finger containing assembly, one end of the torsion spring is in contact connection or fixed connection with the lower probe shell, and the other end of the torsion spring is in fixed connection or contact connection with the upper probe shell;
the temperature sensor is configured to: measuring the ambient temperature and the finger temperature;
the finger-receiving assembly is configured to: accommodating a finger;
the heat conducting rod is arranged vertically or approximately vertically to the finger containing assembly and is arranged to: transferring finger heat to the first and second thermistors;
the LED and the photoelectric receiver are respectively positioned on the upper side and the lower side of the finger containing component and are oppositely arranged, and the LED is arranged as follows: emitting light; the photoelectric receiver is arranged to: receiving light left after the light emitted by the LED passes through the finger;
the humidity sensor is configured to: ambient humidity and finger humidity were measured.
2. The blood glucose measurement probe of claim 1, further comprising a probe connection wire, wherein,
the temperature sensor, the first thermistor, the second thermistor, the photoelectric receiver, the LED and the humidity sensor are all electrically connected with the probe connecting wire through a connector on a bottom plate of the blood glucose measuring probe;
the probe connecting wire is electrically connected with the power supply and the processor.
3. The blood glucose measurement probe of claim 2, further comprising a grommet press configured to: and connecting the probe connecting wire with the connector and then sealing the probe connecting wire.
4. The blood glucose measurement probe of claim 1, further comprising: a heat sink sheet, wherein,
the heat sink is configured to: after the finger is put into the blood sugar measuring probe, the finger is separated from the heat conducting rod, and after the finger is taken out of the blood sugar measuring probe, the finger is contacted with the heat conducting rod to radiate heat for the heat conducting rod.
5. The blood glucose measurement probe of claim 4, further comprising a thermally conductive rod support member secured at one end to the heat sink and configured to: supporting the heat conducting rod.
6. The blood glucose measurement probe of claim 5, wherein one end of the heat conducting rod support member is secured to the heat sink by a snap fit.
7. The blood glucose measurement probe of claim 6, wherein the finger receiving assembly comprises an upper silicone pad and a lower silicone pad, the upper silicone pad being secured to the probe upper shell by an upper silicone pad adhesive plate, the lower silicone pad being secured to the probe lower shell by a lower silicone pad adhesive plate.
8. The blood glucose measurement probe of claim 7, further comprising a spring plate and a compression spring, wherein,
one end of the elastic sheet is fixedly connected with the upper silica gel pad pasting plate, and the other end of the elastic sheet is fixedly connected with the probe upper shell;
the compression spring is positioned in the heat conducting rod supporting piece, one end of the compression spring is abutted against the heat conducting rod supporting piece, the other end of the compression spring is abutted against the heat conducting rod, and the compression spring enables the heat conducting rod to be in close contact with the radiating fin.
9. The blood glucose measurement probe of claim 8,
one end of the radiating fin is fixedly connected with the other end of the heat conducting rod supporting piece, the other end of the radiating fin is fixedly connected with the lower silica gel pad pasting plate, and the lower silica gel pad pasting plate is fixedly connected with the lower probe shell;
the heat conduction rod protrudes out of the surface of the lower silica gel pad before fingers are placed into the finger accommodating assembly, the fingers move downwards after being placed into the finger accommodating assembly due to being pressed, and the compression spring provides force required by close contact between the heat conduction rod and the fingers.
10. The blood glucose measurement probe of claim 2, wherein the temperature sensor is an infrared radiation temperature sensor further configured to: sending its measured temperature to the processor.
11. The blood glucose measurement probe of claim 2, wherein the first and second thermistors are further configured to send the respective measured heat to the processor such that the processor measures the blood flow rate of the person based on changes in temperature.
12. The blood glucose measurement probe of claim 2, wherein the LED is a 4-band LED that emits light at 660nm, 730nm, 805nm, and 940nm in that order.
13. The blood glucose measurement probe of any one of claims 2-12, wherein the humidity sensor is further configured to: and sending the measured environment humidity and the measured finger humidity to the processor, so that the processor can calculate the heat dissipated by the human body through evaporation according to the environment humidity and the finger humidity.
14. A blood glucose measuring device comprising the blood glucose measuring probe of any one of claims 1-13, further comprising a processor electrically connected to the probe connection wire of the blood glucose measuring probe, arranged to: and receiving various signals sent by the blood sugar measuring probe, and measuring the blood sugar of the human body according to the various signals received from the blood sugar measuring probe.
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| CN201910754311.XA CN112386252A (en) | 2019-08-15 | 2019-08-15 | Blood glucose measuring probe and blood glucose measuring device and method |
| PCT/CN2019/103122 WO2021026967A1 (en) | 2019-08-15 | 2019-08-28 | Blood glucose measurement probe and blood glucose measurement device and method |
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| CN114098724A (en) * | 2021-11-22 | 2022-03-01 | 乐普（北京）医疗器械股份有限公司 | Blood glucose prediction method and device based on optical signal characteristics and metabolic heat characteristics |
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| WO2021026967A1 (en) | 2021-02-18 |
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