CN112354421A - Raw materials mixing arrangement is used in gene medicine research and development - Google Patents

Raw materials mixing arrangement is used in gene medicine research and development Download PDF

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Publication number
CN112354421A
CN112354421A CN202110040250.8A CN202110040250A CN112354421A CN 112354421 A CN112354421 A CN 112354421A CN 202110040250 A CN202110040250 A CN 202110040250A CN 112354421 A CN112354421 A CN 112354421A
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CN
China
Prior art keywords
rod
mixing
rods
driving
bevel gear
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Pending
Application number
CN202110040250.8A
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Chinese (zh)
Inventor
陈文锦
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Cytate Biomedical(guangzhou) Technologies Inc
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Cytate Biomedical(guangzhou) Technologies Inc
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Priority to CN202110040250.8A priority Critical patent/CN112354421A/en
Publication of CN112354421A publication Critical patent/CN112354421A/en
Pending legal-status Critical Current

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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/40Mixers with shaking, oscillating, or vibrating mechanisms with an axially oscillating rotary stirrer
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00Other mixers; Mixing plants; Combinations of mixers
    • B01F33/50Movable or transportable mixing devices or plants
    • B01F33/501Movable mixing devices, i.e. readily shifted or displaced from one place to another, e.g. portable during use
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/30Driving arrangements; Transmissions; Couplings; Brakes
    • B01F35/32Driving arrangements
    • B01F35/32005Type of drive
    • B01F35/3204Motor driven, i.e. by means of an electric or IC motor
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F2101/00Mixing characterised by the nature of the mixed materials or by the application field
    • B01F2101/22Mixing of ingredients for pharmaceutical or medical compositions

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  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mixers Of The Rotary Stirring Type (AREA)

Abstract

The invention discloses a raw material mixing device for gene drug research and development, which comprises a mixing shell, a feeding hole, a discharging hole and a valve, wherein the mixing shell is provided with a feeding hole; the upper end and the lower end of the mixing shell are respectively provided with a feeding hole for feeding and a discharging hole for discharging, and the discharging hole is provided with a valve for controlling the opening and the closing of the discharging hole; the stirring mechanism is used for mixing the raw materials; the stirring mechanism comprises a base, an inner rotating rod, an outer rotating rod, an inner cross rod, an outer cross rod and a stirring longitudinal rod. The raw material mixing device for gene drug research and development is provided with the stirring mechanism and the driving mechanism, and can drive the plurality of stirring longitudinal rods to rotate reversely, so that raw materials can be fully stirred; through setting up pushing mechanism, can drive rabbling mechanism up-and-down reciprocating motion to stirring efficiency has further been improved.

Description

Raw materials mixing arrangement is used in gene medicine research and development
Technical Field
The invention relates to a wide range, in particular to a raw material mixing device for gene medicine research and development.
Background
With the development of medical science and technology, more and more attention is paid to the research and development of medicines for different diseases, and a medicine dispensing device is required to be used for dispensing medicines during the research and development of gene medicines. Most current gene medicines often need stir the raw materials of medicine and mix when research and development, and most stirring mixing arrangement that has now all is that the motor drives the (mixing) shaft and rotates and mix, adopts this kind of mode to mix, and the raw materials can rotate along with the rotation of (mixing) shaft to lead to mixing efficiency lower.
Disclosure of Invention
The present invention is directed to solving the above problems of the prior art by providing a raw material mixing apparatus for gene drug development.
In order to achieve the purpose, the invention provides the following technical scheme:
a raw material mixing device for gene drug research and development comprises a mixing shell, a feed inlet, a discharge outlet and a valve; the upper end and the lower end of the mixing shell are respectively provided with a feeding hole for feeding and a discharging hole for discharging, and the discharging hole is provided with a valve for controlling the opening and the closing of the discharging hole; the stirring mechanism is used for mixing the raw materials; the stirring mechanism comprises a base, an inner rotating rod, an outer rotating rod, an inner cross rod, an outer cross rod and a stirring longitudinal rod; a movable plate is arranged in the mixing shell, and a base is arranged at the bottom of the movable plate; an inner rotating rod is rotatably arranged in the base, and an outer rotating rod is rotatably arranged on the outer side of the inner rotating rod; a plurality of inner cross rods and outer cross rods are fixed on the outer sides of the bottoms of the inner rotating rods and the outer rotating rods at equal intervals along the ring shape respectively, and the inner cross rods are shorter than the outer cross rods; a plurality of longitudinal stirring rods for mixing the raw materials are fixed at the bottoms of the inner transverse rod and the outer transverse rod at equal intervals, and the longitudinal stirring rods arranged on the outer transverse rod are positioned at the outer sides of the longitudinal stirring rods arranged on the inner transverse rod; and a driving mechanism for driving the inner rotating rod and the outer rotating rod to rotate reversely is arranged below the movable plate.
As a further scheme of the invention: the driving mechanism comprises a driving motor, a driving bevel gear, an upper driven bevel gear and a lower driven bevel gear; a driving motor is fixed at the bottom of the movable plate, and a driving bevel gear is fixed at the rotating end of the driving motor; the upper end and the lower end of the driving bevel gear are respectively meshed with the upper driven bevel gear and the lower driven bevel gear; and the upper driven bevel gear and the lower driven bevel gear are respectively fixed on the inner rotating rod and the outer rotating rod.
As a still further scheme of the invention: a pushing mechanism for pushing the movable plate to reciprocate up and down is also arranged in the mixing shell; the pushing mechanism comprises a pushing motor, a driving gear, a driven gear, a screw rod, a sleeve and a pushing rod; a pushing motor is arranged on the outer side of the mixing shell, and the rotating end of the pushing motor rotatably penetrates through the side wall of the mixing shell and is connected with one end of a single screw rod rotatably arranged in the mixing shell; the number of the screw rods is two, and a driving gear and a driven gear are respectively fixed on the two screw rods; the driving gear and the driven gear are meshed with each other and have the same structure; reciprocating chutes are symmetrically arranged on the left and the right of the screw rods, and the rotating directions of the reciprocating chutes of the two screw rods are opposite; the reciprocating chutes of the two screw rods are respectively matched with and rotate with a sleeve; the bottoms of the four sleeves are respectively hinged with one ends of the four push rods; the other ends of the four pushing rods are hinged on the movable plate.
As a still further scheme of the invention: a plurality of locating levers are symmetrically arranged in the mixing shell, and the movable plate is arranged on the locating levers in a sliding mode.
As a still further scheme of the invention: the bottom of the mixing shell is designed to be downward inclined, and the discharge hole is positioned on one side of the lowest end of the mixing shell.
As a still further scheme of the invention: the outer side of the mixing shell is also provided with a control button which is convenient for controlling the driving motor and the pushing motor to work.
As a still further scheme of the invention: the bottom of the mixing shell is also symmetrically provided with a plurality of wheel mechanisms which are convenient to move; the wheel mechanism comprises an outer rod, an inner rod, a damping spring and wheels; an outer rod is fixed at the bottom of the mixing shell, and an inner rod is arranged in the outer rod in a sliding mode; the outer rod is connected with the inner rod through a damping spring, and the bottom of the inner rod is rotatably provided with wheels.
Compared with the prior art, the invention has the beneficial effects that: through the arrangement of the stirring mechanism and the driving mechanism, the plurality of longitudinal stirring rods can be driven to rotate reversely, so that raw materials can be fully stirred; through setting up pushing mechanism, can drive rabbling mechanism up-and-down reciprocating motion to stirring efficiency has further been improved.
Drawings
FIG. 1 is a schematic view showing the structure of a raw material mixing apparatus for gene drug development in example 1.
FIG. 2 is a schematic diagram showing the structure of a pushing mechanism of the raw material mixing apparatus for gene drug research in example 1.
FIG. 3 is a schematic view showing the structure of a raw material mixing apparatus for gene drug development in example 2.
In the figure: 1. a mixing housing; 2. a feed inlet; 3. a discharge port; 4. a valve; 5. a movable plate; 6. a base; 7. an inner rotating rod; 8. an outer rotating rod; 9. an inner cross bar; 10. an outer cross bar; 11. a longitudinal stirring rod; 12. a drive motor; 13. a drive bevel gear; 14. an upper driven bevel gear; 15. a lower driven bevel gear; 16. positioning a rod; 17. a push motor; 18. a driving gear; 19. a driven gear; 20. a screw rod; 21. a sleeve; 22. a push rod; 23. an outer rod; 24. an inner rod; 25. a damping spring; 26. and (4) wheels.
Detailed Description
The technical solution of the present invention will be described in further detail with reference to specific embodiments.
Example 1
Referring to fig. 1-2, the present embodiment provides a raw material mixing device for gene drug development, including a mixing housing 1, a feeding port 2, a discharging port 3 and a valve 4; the upper end and the lower end of the mixing shell 1 are respectively provided with a feeding hole 2 for feeding and a discharging hole 3 for discharging, and the discharging hole 3 is provided with a valve 4 for controlling the opening and the closing of the discharging hole 3; the stirring mechanism is used for mixing the raw materials; the stirring mechanism comprises a base 6, an inner rotating rod 7, an outer rotating rod 8, an inner cross rod 9, an outer cross rod 10 and a longitudinal stirring rod 11; a movable plate 5 is arranged in the mixing shell 1, and a base 6 is arranged at the bottom of the movable plate 5; an inner rotating rod 7 is rotatably arranged in the base 6, and an outer rotating rod 8 is rotatably arranged on the outer side of the inner rotating rod 7; a plurality of inner cross rods 9 and outer cross rods 10 are respectively fixed on the outer sides of the bottoms of the inner rotating rod 7 and the outer rotating rod 8 at equal intervals along a ring shape, and the inner cross rods 9 are shorter than the outer cross rods 10; a plurality of longitudinal stirring rods 11 for mixing raw materials are fixed at equal intervals at the bottoms of the inner cross rod 9 and the outer cross rod 10, and the longitudinal stirring rods 11 arranged on the outer cross rod 10 are positioned at the outer sides of the longitudinal stirring rods 11 arranged on the inner cross rod 9; the driving mechanism for driving the inner rotating rod 7 and the outer rotating rod 8 to rotate reversely is arranged below the movable plate 5; set up like this, when dwang 7 and outer dwang 8 antiport in the actuating mechanism drive to drive horizontal pole 9 and outer horizontal pole 10 antiport in a plurality of, thereby drive 11 antiport of a plurality of stirring vertical poles, thereby can carry out intensive mixing to the raw materials, stirring efficiency is higher.
Further, the driving mechanism comprises a driving motor 12, a driving bevel gear 13, an upper driven bevel gear 14 and a lower driven bevel gear 15; a driving motor 12 is fixed at the bottom of the movable plate 5, and a driving bevel gear 13 is fixed at the rotating end of the driving motor 12; the upper end and the lower end of the driving bevel gear 13 are respectively meshed with an upper driven bevel gear 14 and a lower driven bevel gear 15; the upper driven bevel gear 14 and the lower driven bevel gear 15 are respectively fixed on the inner rotating rod 7 and the outer rotating rod 8; so configured, when the driving motor 12 is operated, the driving bevel gear 13 is driven to rotate, thereby driving the upper driven bevel gear 14 and the lower driven bevel gear 15 to rotate in opposite directions, and thereby driving the inner rotating rod 7 and the outer rotating rod 8 to rotate in opposite directions.
In order to further improve the mixing efficiency, a pushing mechanism for pushing the movable plate 5 to reciprocate up and down is further arranged in the mixing shell 1; the pushing mechanism comprises a pushing motor 17, a driving gear 18, a driven gear 19, a screw rod 20, a sleeve 21 and a pushing rod 22; a pushing motor 17 is arranged on the outer side of the mixing shell 1, and the rotating end of the pushing motor 17 rotatably penetrates through the side wall of the mixing shell 1 and is connected with one end of a single screw rod 20 rotatably arranged in the mixing shell 1; the number of the screw rods 20 is two, and a driving gear 18 and a driven gear 19 are respectively fixed on the two screw rods 20; the driving gear 18 and the driven gear 19 are meshed with each other and have the same structure; reciprocating chutes are symmetrically arranged on the left and the right of the screw rods 20, and the rotating directions of the reciprocating chutes of the two screw rods 20 are opposite; the reciprocating chutes of the two screw rods 20 are respectively matched with and rotated with a sleeve 21; the bottoms of the four sleeves 21 are respectively hinged with one ends of four push rods 22; the other ends of the four pushing rods 22 are hinged on the movable plate 5; set up like this, when pushing motor 17 during operation, drive single lead screw 20 and rotate, because driving gear 18 and driven gear 19 intermeshing and structure are the same, thereby two lead screw 20 antiport, because the reciprocal spout of two lead screws 20 is turned to opposite soon, thereby the sleeve 21 that is located both sides can reciprocate be close to and keep away from, thereby promote four catch bar 22 reciprocating swing, thereby promote up-and-down reciprocating motion of fly leaf 5, thereby drive rabbling mechanism reciprocating motion from top to bottom, thereby can further promote the stirring effect.
In order to make the movable plate 5 more stable during the movement, a plurality of positioning rods 16 are symmetrically arranged in the hybrid housing 1, and the movable plate 5 is slidably arranged on the plurality of positioning rods 16.
In order to facilitate discharging, the bottom of the mixing housing 1 is formed to be downwardly inclined, and the discharging port 3 is located at the lowest end side thereof.
In order to facilitate the operation of the control device, the outer side of the mixing housing 1 is further provided with control buttons for facilitating the operation of the driving motor 12 and the pushing motor 17.
The working principle of the embodiment is as follows: when the driving motor 12 works, the driving bevel gear 13 is driven to rotate, so that the upper driven bevel gear 14 and the lower driven bevel gear 15 are driven to reversely rotate, the inner rotating rod 7 and the outer rotating rod 8 are driven to reversely rotate, the plurality of inner transverse rods 9 and the plurality of outer transverse rods 10 are driven to reversely rotate, the plurality of stirring longitudinal rods 11 are driven to reversely rotate, so that raw materials can be fully stirred, and the stirring efficiency is high.
When the driving motor 17 during operation, drive single lead screw 20 and rotate, because driving gear 18 and driven gear 19 intermeshing and the structure is the same, thereby two lead screw 20 antiport, because the reciprocal spout of two lead screws 20 is turned to opposite soon, thereby the sleeve 21 that is located both sides can reciprocate be close to and keep away from, thereby promote four catch bar 22 reciprocating swing, thereby promote the up-and-down reciprocating motion of fly leaf 5, thereby drive rabbling mechanism reciprocating motion from top to bottom, thereby can further promote the stirring effect.
Example 2
Referring to fig. 3, the embodiment is further improved on the basis of embodiment 1, and the improvement is as follows: in order to facilitate moving equipment, a plurality of wheel mechanisms which are convenient to move are symmetrically arranged at the bottom of the mixing shell 1; the wheel mechanism comprises an outer rod 23, an inner rod 24, a damping spring 25 and a wheel 26; an outer rod 23 is fixed at the bottom of the mixing shell 1, and an inner rod 24 is arranged in the outer rod 23 in a sliding manner; the outer rod 23 and the inner rod 24 are connected through a damping spring 25, and the bottom of the inner rod 24 is rotatably provided with a wheel 26.
While the preferred embodiments of the present invention have been described in detail, the present invention is not limited to the above embodiments, and various changes can be made without departing from the spirit of the present invention within the knowledge of those skilled in the art.

Claims (7)

1. A raw material mixing device for gene drug research and development comprises a mixing shell (1), a feeding hole (2), a discharging hole (3) and a valve (4); the upper end and the lower end of the mixing shell (1) are respectively provided with a feeding hole (2) for feeding and a discharging hole (3) for discharging, and the discharging hole (3) is provided with a valve (4) for controlling the opening and the closing of the discharging hole; the stirring mechanism is used for mixing the raw materials; the stirring mechanism is characterized by comprising a base (6), an inner rotating rod (7), an outer rotating rod (8), an inner cross rod (9), an outer cross rod (10) and a stirring longitudinal rod (11); a movable plate (5) is arranged in the mixing shell (1), and a base (6) is arranged at the bottom of the movable plate (5); an inner rotating rod (7) is rotatably arranged in the base (6), and an outer rotating rod (8) is rotatably arranged on the outer side of the inner rotating rod (7); a plurality of inner cross rods (9) and outer cross rods (10) are respectively fixed on the outer sides of the bottoms of the inner rotating rod (7) and the outer rotating rod (8) at equal intervals along a ring shape, and the inner cross rods (9) are shorter than the outer cross rods (10); a plurality of longitudinal stirring rods (11) for mixing the raw materials are fixed at the bottoms of the inner cross rod (9) and the outer cross rod (10) at equal intervals, and the longitudinal stirring rods (11) arranged on the outer cross rod (10) are positioned at the outer sides of the longitudinal stirring rods (11) arranged on the inner cross rod (9); the driving mechanism for driving the inner rotating rod (7) and the outer rotating rod (8) to rotate reversely is arranged below the movable plate (5).
2. The raw material mixing apparatus for gene drug development according to claim 1, wherein the driving mechanism comprises a driving motor (12), a driving bevel gear (13), an upper driven bevel gear (14), and a lower driven bevel gear (15); a driving motor (12) is fixed at the bottom of the movable plate (5), and a driving bevel gear (13) is fixed at the rotating end of the driving motor (12); the upper end and the lower end of the driving bevel gear (13) are respectively meshed with an upper driven bevel gear (14) and a lower driven bevel gear (15); the upper driven bevel gear (14) and the lower driven bevel gear (15) are respectively fixed on the inner rotating rod (7) and the outer rotating rod (8).
3. The raw material mixing device for gene drug development according to claim 1, wherein a pushing mechanism for pushing the movable plate (5) to reciprocate up and down is further provided in the mixing housing (1); the pushing mechanism comprises a pushing motor (17), a driving gear (18), a driven gear (19), a screw rod (20), a sleeve (21) and a pushing rod (22); a pushing motor (17) is arranged on the outer side of the mixing shell (1), and the rotating end of the pushing motor (17) rotatably penetrates through the side wall of the mixing shell (1) and is connected with one end of a single screw rod (20) rotatably arranged in the mixing shell (1); the number of the screw rods (20) is two, and a driving gear (18) and a driven gear (19) are respectively fixed on the two screw rods (20); the driving gear (18) and the driven gear (19) are meshed with each other and have the same structure; reciprocating chutes are symmetrically arranged on the left and the right of the screw rods (20), and the rotating directions of the reciprocating chutes of the two screw rods (20) are opposite; the reciprocating chutes of the two screw rods (20) are respectively matched with and rotated with a sleeve (21); the bottoms of the four sleeves (21) are respectively hinged with one ends of four push rods (22); the other ends of the four pushing rods (22) are hinged on the movable plate (5).
4. The mixing apparatus for gene drug development raw material according to claim 3, wherein a plurality of positioning rods (16) are symmetrically disposed in the mixing housing (1), and the movable plate (5) is slidably disposed on the plurality of positioning rods (16).
5. The raw material mixing apparatus for gene drug development according to claim 4, wherein the bottom of the mixing housing (1) is formed in a downwardly inclined shape, and the discharge port (3) is located at the side of the lowest end thereof.
6. The raw material mixing device for gene drug development according to claim 5, wherein the outer side of the mixing housing (1) is further provided with a control button for controlling the operation of the driving motor (12) and the pushing motor (17).
7. The raw material mixing device for gene drug development according to claim 6, wherein the bottom of the mixing housing (1) is further symmetrically provided with a plurality of wheel mechanisms for facilitating movement; the wheel mechanism comprises an outer rod (23), an inner rod (24), a damping spring (25) and a wheel (26); an outer rod (23) is fixed at the bottom of the mixing shell (1), and an inner rod (24) is arranged in the outer rod (23) in a sliding manner; the outer rod (23) is connected with the inner rod (24) through a damping spring (25), and the bottom of the inner rod (24) is rotatably provided with a wheel (26).
CN202110040250.8A 2021-01-13 2021-01-13 Raw materials mixing arrangement is used in gene medicine research and development Pending CN112354421A (en)

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CN202110040250.8A CN112354421A (en) 2021-01-13 2021-01-13 Raw materials mixing arrangement is used in gene medicine research and development

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Application Number Priority Date Filing Date Title
CN202110040250.8A CN112354421A (en) 2021-01-13 2021-01-13 Raw materials mixing arrangement is used in gene medicine research and development

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113385087A (en) * 2021-05-28 2021-09-14 南京晓庄学院 Manual-automatic integrated equipment for straw fertilizer production
CN113547637A (en) * 2021-06-05 2021-10-26 赵静 Two-stage pulping machine

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61192331A (en) * 1984-07-02 1986-08-26 Hitachi Ltd Stirring apparatus for submerged granulation
CN109603637A (en) * 2019-01-17 2019-04-12 张磊 A kind of industrial chemicals mixing stirring device of mutual impact type
CN111264153A (en) * 2020-01-15 2020-06-12 安徽科技学院 Fertilizing device capable of dynamically adjusting fertilizing amount and adjusting method
CN211025976U (en) * 2019-10-21 2020-07-17 重庆市尚言吉玻璃有限公司 Printing machine printing ink ration diluting device
CN211586217U (en) * 2019-12-27 2020-09-29 定州市润枫防水材料有限公司 Make things convenient for agitator tank for waterproof material production of ejection of compact
CN112106667A (en) * 2020-09-29 2020-12-22 王娟娟 Full-automatic cream whipper

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61192331A (en) * 1984-07-02 1986-08-26 Hitachi Ltd Stirring apparatus for submerged granulation
CN109603637A (en) * 2019-01-17 2019-04-12 张磊 A kind of industrial chemicals mixing stirring device of mutual impact type
CN211025976U (en) * 2019-10-21 2020-07-17 重庆市尚言吉玻璃有限公司 Printing machine printing ink ration diluting device
CN211586217U (en) * 2019-12-27 2020-09-29 定州市润枫防水材料有限公司 Make things convenient for agitator tank for waterproof material production of ejection of compact
CN111264153A (en) * 2020-01-15 2020-06-12 安徽科技学院 Fertilizing device capable of dynamically adjusting fertilizing amount and adjusting method
CN112106667A (en) * 2020-09-29 2020-12-22 王娟娟 Full-automatic cream whipper

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113385087A (en) * 2021-05-28 2021-09-14 南京晓庄学院 Manual-automatic integrated equipment for straw fertilizer production
CN113547637A (en) * 2021-06-05 2021-10-26 赵静 Two-stage pulping machine

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