CN1123341C - Liquid propanethiophenyl imidzole for expelling parasites from body of livestock and its preparing process - Google Patents
Liquid propanethiophenyl imidzole for expelling parasites from body of livestock and its preparing process Download PDFInfo
- Publication number
- CN1123341C CN1123341C CN 00110198 CN00110198A CN1123341C CN 1123341 C CN1123341 C CN 1123341C CN 00110198 CN00110198 CN 00110198 CN 00110198 A CN00110198 A CN 00110198A CN 1123341 C CN1123341 C CN 1123341C
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- Prior art keywords
- albendazole
- livestock
- medicinal liquid
- expelling
- liquid
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Abstract
The present invention relates to propanethiophenyl imidzole medical liquid for expelling livestock entozoic and a preparation method thereof. The propanethiophenyl imidzole medical liquid is reddish brown clear medical liquid comprising 10 wt% of albendazole, 1 wt% of sorbic acid, 60 wt% of organic solvent polyethylene glycol-400 and 29% of water. The administration is accurate and convenient and livestock difficultly vomit by the method that the medical liquid of the present invention is administrated in mouths of the livestock by a quantitative injector or by intramuscular injection. The medical liquid has the advantages of large dispersion area and easy absorption, and thus, the medical effect is improved.
Description
The present invention relates to a kind of veterinary drug and preparation method thereof.
Along with improving constantly of people's living standard, the demand of meats such as cattle, sheep, pig is constantly increased, this has just promoted Developing of Animal Industry greatly.Worm's ovum is generally survived in plant and meadow, and parasitic infection often takes place in raising and growth course domestic animal, and special is the pilosity district of parasitic disease in the pastoral area, grassland, and is very big for animal husbandry harm like this, restricted Developing of Animal Industry to a certain extent.At present, the wide spectrum specific drug of domestic expeling domestic animal endoparasite is an Albendazole, and it is than other all kinds of anthelmintics more economy, low toxicity.But it is water insoluble, generally can only make tablet, yet tablet is taken very inconvenient to domestic animal, and it is loaded down with trivial details to throw the clothes operation, and, easily cause the domestic animal vomiting, cause taking dose inaccurate and influence anthelminthic effect.
Purpose of the present invention, provide a kind of processing technology simple, throw that clothes are convenient, anthelminthic effect is good, domestic animal is difficult for vomiting, but folk prescription, compound recipe are made the Albendazole medicinal liquid and preparation method thereof of the expelling and controlling parasite in livestock of oral agents or intramuscular injection agent.
The Albendazole medicinal liquid of expelling and controlling parasite in livestock is a rufous, and its active ingredient is principal agent Albendazole 2-20%, sorbic acid 0.1--3%, organic solvent 40-80%, water 15-40% in the Albendazole complex that contains iodine by weight percentage.
The preparation method of the Albendazole medicinal liquid of expelling and controlling parasite in livestock:
Get Albendazole 2-20%, add hydrochloric acid 2-20%, iodine liquid 1-3%, fully stir, make its generation contain the Albendazole complex compound sediment of iodine, hydrochloric acid, unnecessary iodine are removed in washing then, and inclining supernatant, add organic solvent 40-80% dissolving, add again after sorbic acid 0.1-3%, water 15-40% stir, be the clear and bright medicinal liquid of finished product rufous.
Above-mentioned organic solvent comprises 12 propylene glycol, glycerol, ethanol, Polyethylene Glycol.
Advantage of the present invention:
1, simple, the steady quality of production technology
By the Albendazole that is insoluble to organic solvent, by adding after hydrochloric acid, iodine liquid forms the rufous complex, can be dissolved in organic solvent and the water, can place the long period and never degenerate, need not matching while using;
2, the throwing clothes are simple, dosage is accurate
This medicinal liquid drops in the domestic animal oral cavity or intramuscular injection by the calibrated shot device, and accurate when throwing clothes, convenient, domestic animal is difficult for vomiting, can alleviate pastoral area personnel's labor intensity greatly, and it is simple to operate to throw clothes than the tablet in the existing use, and dosage is accurate;
3, anthelminthic effect is remarkable
This medicinal liquid disperses area big, easily is absorbed, thereby improves its drug effect, drives to control parasite and be better than the like product tablet, can be mass-produced, and can satisfy the needs that pastoral area herdsman and raiser carry out the preventing and treating verminosis medication to cows, flock of sheep.
Embodiment:
The Albendazole medicinal liquid of expelling and controlling parasite in livestock is the clear and bright medicinal liquid of rufous (above-mentioned percentage ratio is weight percentage) that the Albendazole complex that contains iodine contains principal agent Albendazole 10%, sorbic acid 1%, organic solvent Polyethylene Glycol-400 60%, water 29%.
The preparation method of the Albendazole medicinal liquid of expelling and controlling parasite in livestock, be to get Albendazole 10%, add hydrochloric acid 10%, iodine liquid 2.5%, stir, generate the Albendazole complex compound sediment that contains iodine, washing, inclining supernatant, adds Polyethylene Glycol-400 60% dissolving, adds sorbic acid 1%, water 29% again, stir, be finished product.
Character: the clear and bright medicinal liquid of rufous.
Claims (3)
1, the Albendazole medicinal liquid of expelling and controlling parasite in livestock is characterized in that this medicine is to contain by weight percentage that the principal agent Albendazole is the clear and bright medicinal liquid of rufous of 2-20%, sorbic acid 0.1-3%, organic solvent 40-80%, water 15-40% in the Albendazole complex of iodine; Organic solvent can be 12 propylene glycol, glycerol, ethanol, also can be Polyethylene Glycol.
2, the Albendazole medicinal liquid of expelling and controlling parasite in livestock according to claim 1 is characterized in that this medicine is for principal agent Albendazole in the Albendazole complex that contains iodine by weight percentage is 10%, the clear and bright medicinal liquid of rufous of sorbic acid 1%, organic solvent Polyethylene Glycol-400 60%, water 29%.
3, the preparation method of the Albendazole medicinal liquid of expelling and controlling parasite in livestock, be to get Albendazole 10%, add hydrochloric acid 10%, iodine liquid 2.5%, fully stir, make its generation contain the Albendazole complex compound sediment of iodine, washing then, inclining supernatant, adds Polyethylene Glycol-400 60% dissolving, adds sorbic acid 1%, water 29% again, stir, be the clear and bright medicinal liquid of rufous.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 00110198 CN1123341C (en) | 2000-03-13 | 2000-03-13 | Liquid propanethiophenyl imidzole for expelling parasites from body of livestock and its preparing process |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 00110198 CN1123341C (en) | 2000-03-13 | 2000-03-13 | Liquid propanethiophenyl imidzole for expelling parasites from body of livestock and its preparing process |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1313088A CN1313088A (en) | 2001-09-19 |
| CN1123341C true CN1123341C (en) | 2003-10-08 |
Family
ID=4580208
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 00110198 Expired - Fee Related CN1123341C (en) | 2000-03-13 | 2000-03-13 | Liquid propanethiophenyl imidzole for expelling parasites from body of livestock and its preparing process |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1123341C (en) |
-
2000
- 2000-03-13 CN CN 00110198 patent/CN1123341C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN1313088A (en) | 2001-09-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C06 | Publication | ||
| PB01 | Publication | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C19 | Lapse of patent right due to non-payment of the annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |