CN112299969A - Application of imidazole carbonate in preparation of important chemical raw materials - Google Patents
Application of imidazole carbonate in preparation of important chemical raw materials Download PDFInfo
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- CN112299969A CN112299969A CN202011371338.XA CN202011371338A CN112299969A CN 112299969 A CN112299969 A CN 112299969A CN 202011371338 A CN202011371338 A CN 202011371338A CN 112299969 A CN112299969 A CN 112299969A
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- cyclohexanone
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- imidazole carbonate
- imidazole
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
- C07C45/32—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation with molecular oxygen
- C07C45/33—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation with molecular oxygen of CHx-moieties
- C07C45/34—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation with molecular oxygen of CHx-moieties in unsaturated compounds
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J27/00—Catalysts comprising the elements or compounds of halogens, sulfur, selenium, tellurium, phosphorus or nitrogen; Catalysts comprising carbon compounds
- B01J27/06—Halogens; Compounds thereof
- B01J27/128—Halogens; Compounds thereof with iron group metals or platinum group metals
- B01J27/13—Platinum group metals
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/54—Improvements relating to the production of bulk chemicals using solvents, e.g. supercritical solvents or ionic liquids
Abstract
The invention provides an application of imidazole carbonate in preparing cyclohexanone which is an important chemical raw material, which is characterized by comprising the following steps: putting cyclohexene in a reaction vessel, adding an ionic liquid imidazole carbonate and a Wacker catalyst, introducing an oxygen source, stirring and heating to react under normal pressure, and carrying out post-treatment to obtain the cyclohexanone. The imidazole carbonate ionic liquid is used as a solvent, the system can fully react without high pressure, the reaction time is greatly shortened, the higher yield and purity of the product can be ensured, the method is particularly suitable for industrial production, and the unexpected technical effect is achieved.
Description
Technical Field
The invention belongs to the field of organic synthesis, and particularly relates to a preparation method of a chemical intermediate, and more particularly relates to a preparation method of a chemical intermediate cyclohexanone.
Background
Cyclohexanone (Cyclohexanone), also known as anone, is a saturated cyclic ketone in which the carbonyl carbon atom is contained within a six-membered ring. Is a colorless transparent liquid with earthy smell, and has a mint flavor when trace amount of phenol is contained. The impurities are light yellow, generate impurities along with storage time to develop color, are water white to grey yellow and have strong pungent odor, and the cyclohexanone has an anesthetic effect on a human body in a high-concentration water vapor form, causes skin inflammation if contacting the skin for a long time, seriously damages the cornea if entering the eyes carelessly, and therefore strictly avoids contacting the skin and the eyes in the use process. Cyclohexanone is an important organic chemical raw material, is a main intermediate for preparing nylon, adipic acid, caprolactam and the like, is also a main raw material for preparing various vinyl resin paints, is widely used as a solvent for many high molecular polymers, such as soluble cellulose nitrate, coatings, paints and the like, and plays an extremely important role in the aspects of organic chemical industry, coating industry and the like.
The current industrial process for cyclohexanone production mainly comprises the following routes:
(1) the phenol hydrogenation method, which is the earliest industrialized method for producing cyclohexanone, is a gas-phase hydrogenation method and a liquid-phase hydrogenation method, and has the advantages of high product purity, simple product purification process, short process flow and the like. The gas phase hydrogenation method usually adopts 3-5 reactors connected in series, adopts a supported catalyst (usually Pt), has a reaction pressure of 0.1MPa, a reaction temperature of 140-170 ℃, and a yield of cyclohexanone of 81%, but the process needs to vaporize phenol and a solvent methanol, so that the energy consumption is high, and the catalyst is easy to cause carbon deposition to reduce the activity. The liquid phase hydrogenation method usually uses nickel as a catalyst, and compared with gas phase hydrogenation, the liquid phase can be carried out under a milder condition, so that the method is energy-saving and environment-friendly. Both production processes require a supply of hydrogen. The research on the preparation of cyclohexanone by using a phenol gas-phase one-step method is more, but most of the cyclohexanone is prepared by using a noble metal catalyst, such as transition metals of platinum, palladium, ruthenium, nickel and the like, so that the production cost is higher, and the application is limited. The supported Pd catalyst shows excellent activity and selectivity in the reaction of synthesizing cyclohexanone by phenol selective hydrogenation catalysis, and is widely applied to industry once, but the process flow for synthesizing phenol is complex, and phenol is a highly toxic organic substance, so that the preparation of cyclohexanone by a phenol method is almost not adopted at present.
(2) The oxidation method, which is the most important method for producing cyclohexanone in the world at present, mainly uses cyclohexane as a raw material and cobalt salt as a catalyst to synthesize cyclohexanone, and has mild process conditions, but has long continuous operation period, long process route, high energy consumption, heavy pollution, high energy consumption of production process, low conversion rate and multiple side reactions, which cause subsequent separation difficulty; the adoption of boric acid or metaboric acid as a catalyst increases the hydrolysis procedure and the boric acid recovery process, and overcomes the problems of low conversion rate and low selectivity, but the initial investment cost and the operation cost are high.
(3) The cyclohexene hydration method is characterized in that benzene is used as a raw material, transition metal ruthenium is used as a catalyst, hydrogenation is firstly carried out to generate cyclohexene, then the cyclohexene is subjected to the hydration method to generate cyclohexanol, and the cyclohexanol is subjected to hydrogenation reaction to prepare the cyclohexanone.
(4) Cyclohexanol is used as a raw material, a catalyst with complex components is generally used, the preparation of the catalyst is relatively troublesome, the preparation cost is relatively high, and a plurality of side reactions, mainly a polycondensation dehydration reaction between cyclohexanone, a reaction for generating phenol by dehydrogenation and a reaction for generating cyclohexene by dehydration of cyclohexanol, generally occur in the oxidative dehydrogenation process of cyclohexanol.
Disclosure of Invention
The invention aims to overcome the series of defects in the synthesis of cyclohexanone in the prior art, and provides a method for preparing cyclohexanone, which is characterized by comprising the following steps: putting cyclohexene in a reaction vessel, adding an ionic liquid imidazole carbonate and a Wacker catalyst, introducing an oxygen source, stirring and heating to react under normal pressure, and carrying out post-treatment to obtain the cyclohexanone.
According to the preparation method of the cyclohexanone as the chemical intermediate, the imidazole carbonate is selected from one or more of 1-methyl-3-ethyl imidazole carbonate, 1-methyl-3-propyl imidazole carbonate, 1-methyl-3-butyl imidazole carbonate, 1-methyl-3-pentyl imidazole carbonate, 1-methyl-3-hexyl imidazole carbonate or 1-methyl-3-octyl imidazole carbonate.
According to the preparation method of the chemical intermediate cyclohexanone, the Wacker catalyst is selected from PdCl2-CuCl2A catalyst.
According to the preparation method of the cyclohexanone as the chemical intermediate, the oxygen source is selected from air or oxygen.
According to the preparation method of the chemical intermediate cyclohexanone, the heating temperature is 60-100 ℃.
According to the preparation method of the chemical intermediate cyclohexanone, the reaction time is 1-4 h.
According to the preparation method of the chemical intermediate cyclohexanone, the feeding ratio of the cyclohexene, the catalyst and the ionic liquid is 1mol: 1-10 g: 100-200 g.
According to the preparation method of the chemical intermediate cyclohexanone, PdCl in the catalyst is used2And CuCl2The mass ratio of (A) to (B) is 1: 5-10.
According to the preparation method of the chemical intermediate cyclohexanone, the stirring speed is 500-1000 r/min.
According to the preparation method of the chemical intermediate cyclohexanone, the post-treatment process comprises the following steps: after the reaction was completed, the system was slowly returned to room temperature, and distilled under reduced pressure to obtain cyclohexanone.
Further, the present invention also provides a use of an ionic liquid in the preparation of cyclohexanone, preferably, the ionic liquid is imidazole carbonate, further preferably, the imidazole carbonate is selected from one or more of 1-methyl-3-ethyl imidazole carbonate, 1-methyl-3-propyl imidazole acid salt, 1-methyl-3-butyl imidazole carbonate, 1-methyl-3-pentyl imidazole carbonate, 1-methyl-3-hexyl imidazole carbonate, or 1-methyl-3-octyl imidazole carbonate.
The main contributions of the present invention with respect to the prior art are the following:
the invention takes cyclohexene as raw material and PdCl2-CuCl2The catalyst is added with the imidazole carbonate ionic liquid as a solvent for reaction, the raw material and the catalyst can be fully dissolved by using the imidazole carbonate ionic liquid, and the reaction efficiency is greatly improved compared with [ Bmim ]]·PF6The imidazole carbonate ionic liquid is used as a solvent, the system can fully react without high pressure, the reaction time is greatly shortened, the higher yield and purity of the product can be ensured, the method is particularly suitable for industrial production, and the unexpected technical effect is achieved.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present disclosure more apparent, the technical solutions of the embodiments of the present disclosure are clearly and completely described. It is to be understood that the described embodiments are only a few embodiments of the present disclosure, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the described embodiments of the disclosure without any inventive step, are within the scope of protection of the disclosure.
The invention provides a preparation method of cyclohexanone, which is characterized by comprising the following steps: putting cyclohexene in a reaction vessel, adding an ionic liquid imidazole carbonate and a Wacker catalyst, introducing an oxygen source, stirring and heating to react under normal pressure, and carrying out post-treatment to obtain the cyclohexanone.
According to the preparation method of the cyclohexanone as the chemical intermediate, the imidazole carbonate is selected from one or more of 1-methyl-3-ethyl imidazole carbonate, 1-methyl-3-propyl imidazole carbonate, 1-methyl-3-butyl imidazole carbonate, 1-methyl-3-pentyl imidazole carbonate, 1-methyl-3-hexyl imidazole carbonate or 1-methyl-3-octyl imidazole carbonate.
According to the preparation method of the chemical intermediate cyclohexanone, the Wacker catalyst is selected from PdCl2-CuCl2A catalyst.
According to the preparation method of the cyclohexanone as the chemical intermediate, the oxygen source is selected from air or oxygen.
According to the preparation method of the chemical intermediate cyclohexanone, the heating temperature is 60-100 ℃.
According to the preparation method of the chemical intermediate cyclohexanone, the reaction time is 1-4 h.
According to the preparation method of the chemical intermediate cyclohexanone, the feeding ratio of the cyclohexene, the catalyst and the ionic liquid is 1mol: 1-10 g: 100-200 g.
According to the preparation method of the chemical intermediate cyclohexanone, PdCl in the catalyst is used2And CuCl2The mass ratio of (A) to (B) is 1: 5-10.
According to the preparation method of the chemical intermediate cyclohexanone, the stirring speed is 500-1000 r/min.
According to the preparation method of the chemical intermediate cyclohexanone, the post-treatment process comprises the following steps: after the reaction was completed, the system was slowly returned to room temperature, and distilled under reduced pressure to obtain cyclohexanone.
Further, the present invention also provides a use of an ionic liquid in the preparation of cyclohexanone, preferably, the ionic liquid is imidazole carbonate, further preferably, the imidazole carbonate is selected from one or more of 1-methyl-3-ethyl imidazole carbonate, 1-methyl-3-propyl imidazole acid salt, 1-methyl-3-butyl imidazole carbonate, 1-methyl-3-pentyl imidazole carbonate, 1-methyl-3-hexyl imidazole carbonate, or 1-methyl-3-octyl imidazole carbonate.
Example 1
Adding 0.1mol of cyclohexene, 20g of 1-methyl-3-butylimidazole carbonate, 0.5g of copper chloride and 0.1g of palladium chloride into a reactor in sequence, stirring uniformly, continuously introducing oxygen, slowly heating to 60 ℃ under normal pressure, keeping the stirring speed at 500r/min, reacting for 4h, then slowly cooling the system to room temperature, and carrying out reduced pressure distillation to obtain cyclohexanone, wherein the yield is 96.2% and the purity is 99.0%.
Example 2
Adding 0.1mol of cyclohexene, 18g of 1-methyl-3-butylimidazole carbonate, 0.6g of copper chloride and 0.1g of palladium chloride into a reactor in sequence, stirring uniformly, continuously introducing oxygen, slowly heating to 70 ℃ under normal pressure, keeping the stirring speed at 1000r/min, reacting for 4h, then slowly cooling the system to room temperature, and carrying out reduced pressure distillation to obtain the cyclohexanone with the yield of 95.9% and the purity of 99.2%.
Example 3
Adding 0.1mol of cyclohexene, 20g of 1-methyl-3-propyl imidazole carbonate, 0.8g of copper chloride and 0.1g of palladium chloride into a reactor in sequence, stirring uniformly, continuously introducing air, slowly heating to 100 ℃ under normal pressure, keeping the stirring speed at 1000r/min, reacting for 2h, then slowly cooling the system to room temperature, and carrying out reduced pressure distillation to obtain cyclohexanone, wherein the yield is 94.7% and the purity is 99.6%.
Example 4
Adding 1mol of cyclohexene, 180g of 1-methyl-3-pentylimidazole carbonate, 9g of copper chloride and 1g of palladium chloride into a reactor in sequence, uniformly stirring, continuously introducing air, slowly heating to 100 ℃ under normal pressure, keeping the stirring speed at 800r/min, reacting for 4h, then slowly cooling the system to room temperature, and carrying out reduced pressure distillation to obtain cyclohexanone, wherein the yield is 96.1%, and the purity is 99.3%.
Example 5
Adding 1mol of cyclohexene, 200g of 1-methyl-3-hexyl imidazole carbonate, 9g of copper chloride and 1g of palladium chloride into a reactor in sequence, uniformly stirring, continuously introducing air, slowly heating to 60 ℃ under normal pressure, keeping the stirring speed at 1000r/min, reacting for 4h, then slowly cooling the system to room temperature, and carrying out reduced pressure distillation to obtain cyclohexanone, wherein the yield is 95.9%, and the purity is 99.0%.
Example 6
Adding 1mol of cyclohexene, 200g of 1-methyl-3-octyl imidazole carbonate, 9g of copper chloride and 1g of palladium chloride into a reactor in sequence, uniformly stirring, continuously introducing air, slowly heating to 100 ℃ under normal pressure, keeping the stirring speed at 1000r/min, reacting for 4 hours, then slowly cooling the system to room temperature, and carrying out reduced pressure distillation to obtain cyclohexanone, wherein the yield is 96.7%, and the purity is 99.3%.
Comparative example 1
Adding 0.1mol of cyclohexene, 20g of 1-methyl-3-butylimidazole hexafluorophosphate, 0.5g of copper chloride and 0.1g of palladium chloride into a reactor in sequence, stirring uniformly, continuously introducing oxygen, slowly heating to 60 ℃ under normal pressure, keeping the stirring speed at 500r/min, reacting for 4h, then slowly cooling the system to room temperature, and carrying out reduced pressure distillation to obtain the cyclohexanone with the yield of 76.2% and the purity of 85.1%.
Comparative example 2
Adding 0.1mol of cyclohexene, 20g of 1-methyl-3-propyl imidazole carbonate, 0.8g of copper chloride and 0.1g of palladium chloride into a reactor in sequence, stirring uniformly, continuously introducing air, slowly heating to 100 ℃ under normal pressure, keeping the stirring speed at 1000r/min, reacting for 2h, then slowly cooling the system to room temperature, and carrying out reduced pressure distillation to obtain cyclohexanone, wherein the yield is 76.5%, and the purity is 80.3%.
Comparative example 3
Adding 0.1mol of cyclohexene and 20g of 1-methyl-3-butylimidazole hexafluorophosphate into a reactor in sequence, stirring uniformly, continuously introducing oxygen, slowly heating to 60 ℃ under normal pressure, keeping the stirring speed at 500r/min, reacting for 4h, then slowly cooling the system to room temperature, distilling under reduced pressure, and detecting to obtain no cyclohexanone.
Finally, it should be noted that: it should be understood that the above examples are only for clearly illustrating the present invention and are not intended to limit the embodiments. Other variations and modifications will be apparent to persons skilled in the art in light of the above description. And are neither required nor exhaustive of all embodiments. And obvious variations or modifications of the invention may be made without departing from the scope of the invention.
Claims (10)
1. An application of imidazole carbonate in preparing cyclohexanone which is an important chemical raw material.
2. The use of imidazole carbonate according to claim 1 for the preparation of cyclohexanone, an important chemical raw material, characterized by comprising the steps of: putting cyclohexene in a reaction vessel, adding an ionic liquid imidazole carbonate and a Wacker catalyst, introducing an oxygen source, stirring and heating to react under normal pressure, and carrying out post-treatment to obtain the cyclohexanone.
3. The use of an imidazole carbonate according to claim 1 or 2 in the preparation of cyclohexanone, which is an important chemical raw material, wherein the imidazole carbonate is selected from one or more of 1-methyl-3-ethylimidazole carbonate, 1-methyl-3-propyl imidazole acid salt, 1-methyl-3-butyl imidazole carbonate, 1-methyl-3-pentyl imidazole carbonate, 1-methyl-3-hexyl imidazole carbonate, and 1-methyl-3-octyl imidazole carbonate.
4. The use of an imidazole carbonate according to any of the preceding claims in the preparation of cyclohexanone, an important chemical raw material, said Wacker catalyst being selected from PdCl2-CuCl2A catalyst.
5. Use of an imidazole carbonate according to any of the preceding claims in the preparation of cyclohexanone, an important chemical raw material, said source of oxygen being selected from air or oxygen.
6. The use of an imidazole carbonate according to any of the preceding claims for the preparation of cyclohexanone, an important chemical raw material, said heating temperature being 60-100 ℃.
7. The use of an imidazole carbonate according to any of the preceding claims for the preparation of cyclohexanone, an important chemical raw material, the reaction time of the reaction being 1-4 hours.
8. The use of an imidazole carbonate in the preparation of cyclohexanone, an important chemical raw material, according to any of the preceding claims, wherein the charge ratio of cyclohexene, catalyst and ionic liquid is 1mol: 1-10 g: 100-200 g; PdCl in the catalyst2And CuCl2The mass ratio of (A) to (B) is 1: 5-10.
9. The use of an imidazole carbonate according to any of the preceding claims for the preparation of cyclohexanone, an important chemical raw material, said stirring speed being 500-1000 r/min.
10. The use of an imidazole carbonate according to any of the preceding claims for the preparation of cyclohexanone, an important chemical raw material, said post-treatment process being: after the reaction was completed, the system was slowly returned to room temperature, and distilled under reduced pressure to obtain cyclohexanone.
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| CN202011371338.XA CN112299969A (en) | 2020-11-30 | 2020-11-30 | Application of imidazole carbonate in preparation of important chemical raw materials |
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Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105523907A (en) * | 2015-12-14 | 2016-04-27 | 河北工业大学 | Method for directly preparing cyclohexanone from benzene |
| CN107513009A (en) * | 2017-08-18 | 2017-12-26 | 浙江新和成股份有限公司 | A kind of method that cyclopentanone is prepared by oxidation of cyclopentene |
| CN107803220A (en) * | 2017-10-18 | 2018-03-16 | 三峡大学 | A kind of supported imidazole ion liquid catalyst and application on cyclohexanone and cyclohexanol is prepared in catalytic oxidation of cyclohexane |
| CN111217684A (en) * | 2019-10-29 | 2020-06-02 | 山西潞宝兴海新材料有限公司 | Production method for improving yield of cyclohexanone |
| CN111747832A (en) * | 2020-07-17 | 2020-10-09 | 山东卓俊实业有限公司 | Method for preparing cyclohexanone |
| CN111808054A (en) * | 2020-08-17 | 2020-10-23 | 李孝林 | Preparation method of ionic liquid and application of ionic liquid in cyclohexanone synthesis |
| CN112299968A (en) * | 2020-11-26 | 2021-02-02 | 山东卓俊实业有限公司 | Preparation method of chemical raw material |
-
2020
- 2020-11-30 CN CN202011371338.XA patent/CN112299969A/en not_active Withdrawn
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105523907A (en) * | 2015-12-14 | 2016-04-27 | 河北工业大学 | Method for directly preparing cyclohexanone from benzene |
| CN107513009A (en) * | 2017-08-18 | 2017-12-26 | 浙江新和成股份有限公司 | A kind of method that cyclopentanone is prepared by oxidation of cyclopentene |
| CN107803220A (en) * | 2017-10-18 | 2018-03-16 | 三峡大学 | A kind of supported imidazole ion liquid catalyst and application on cyclohexanone and cyclohexanol is prepared in catalytic oxidation of cyclohexane |
| CN111217684A (en) * | 2019-10-29 | 2020-06-02 | 山西潞宝兴海新材料有限公司 | Production method for improving yield of cyclohexanone |
| CN111747832A (en) * | 2020-07-17 | 2020-10-09 | 山东卓俊实业有限公司 | Method for preparing cyclohexanone |
| CN111808054A (en) * | 2020-08-17 | 2020-10-23 | 李孝林 | Preparation method of ionic liquid and application of ionic liquid in cyclohexanone synthesis |
| CN112299968A (en) * | 2020-11-26 | 2021-02-02 | 山东卓俊实业有限公司 | Preparation method of chemical raw material |
Non-Patent Citations (2)
| Title |
|---|
| EFREMOV, G. E. ET AL.: "Ethylene and Cyclohexene Oxidation by p-Benzoquinone, Hydrogen Peroxide,and Oxygen in the Solutions of Cationic Pd(II) Complexes inAcetonitrile-Water and Ionic Liquid-Water Binary Solvents", 《KINETICS AND CATALYSIS》 * |
| JIE SHANSHAN ET AL.: "Facile synthesis of ultra-stable Co-N-C catalysts using cobalt p", 《MOLECULAR CATALYSIS》 * |
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