CN112294326A - Flexible blood glucose electrochemical test probe and assembling method thereof - Google Patents
Flexible blood glucose electrochemical test probe and assembling method thereof Download PDFInfo
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- CN112294326A CN112294326A CN202011386140.9A CN202011386140A CN112294326A CN 112294326 A CN112294326 A CN 112294326A CN 202011386140 A CN202011386140 A CN 202011386140A CN 112294326 A CN112294326 A CN 112294326A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1468—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
- A61B5/1473—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1486—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using enzyme electrodes, e.g. with immobilised oxidase
- A61B5/14865—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using enzyme electrodes, e.g. with immobilised oxidase invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
- A61B2562/12—Manufacturing methods specially adapted for producing sensors for in-vivo measurements
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
- A61B2562/12—Manufacturing methods specially adapted for producing sensors for in-vivo measurements
- A61B2562/125—Manufacturing methods specially adapted for producing sensors for in-vivo measurements characterised by the manufacture of electrodes
Abstract
The invention provides a flexible blood glucose electrochemical test probe, which consists of a first electrode assembly and a second electrode assembly, wherein the first electrode assembly sequentially comprises from bottom to top: the flexible printed circuit comprises a first flexible circuit substrate, a second flexible circuit substrate and a plurality of first conductive layers, wherein the first flexible circuit substrate is provided with a first electrode and at least one first annular external connection bonding pad; a first insulating layer; a first insulating adhesive layer; the second electrode component sequentially comprises from bottom to top: the second flexible circuit substrate is provided with a second electrode and at least one second annular external connection bonding pad; a second insulating layer; a second insulating adhesive layer; the first electrode assembly and the second electrode assembly are adhered together through a second insulating adhesive layer. The flexible blood sugar electrochemical test probe improves the stability and reliability of the probe while ensuring the comfort of a tested person, has lower requirements on a production process and an assembly process, and is more beneficial to realizing large-scale production and processing.
Description
Technical Field
The invention relates to the technical field of blood glucose detection, in particular to a flexible blood glucose electrochemical test probe and an assembling method thereof.
Background
Diabetes is a disease caused by the abnormal condition of pancreas in a patient and the failure to produce sufficient insulin. More severe patients may be accompanied later by a series of complications, such as renal failure, skin ulcers. At the current medical level, no method for radically treating the disease is found, and only blood sugar can be controlled by diet or insulin and the like.
In most cases, diabetes mellitus uses a conventional glucose meter and glucose strip to monitor blood glucose values by measuring the amount of blood glucose by measuring the current produced by the reaction of glucose in the blood and glucose oxidase in the strip. Since the above-mentioned blood sugar test mostly uses finger tip blood, a diabetic needs to measure his or her glucose level every day at a time period designated by a medical staff. Besides the pain caused by the repeated use of the acupuncture blood sampling, the detection mode is also easily influenced by external factors (diet, emotion, exercise and the like), and the change trend of the blood sugar in the body of a patient cannot be effectively monitored.
With the development of blood sugar monitoring technology, products for monitoring dynamic blood sugar in real time appear on the market, and the change of the blood sugar of a human body is monitored in real time through a glucose sensor probe implanted into subcutaneous tissues of the human body. The sensor probe is matched with external equipment, can dynamically monitor the change of the blood sugar value in the body of the diabetic patient within 24 hours, and provides reliable data information for professional medical personnel, so that the diabetic patient can be better treated. At present, the dynamic blood glucose monitoring in the market mainly uses metal electrodes, the user experience is greatly influenced due to overlarge volume or overlarge thickness, the daily life is interfered, and therefore, the size of the flexible implanted electrode is higher in requirement.
Disclosure of Invention
The technical problem to be solved by the invention is to overcome the defects in the known technology, and provide a flexible blood glucose electrochemical test probe, which improves the stability and reliability of the probe while ensuring the comfort of a tested person, has lower requirements on a production process and an assembly process, and is more beneficial to realizing large-scale production and processing.
The invention is realized by the following technical scheme, and the flexible blood glucose electrochemical test probe provided by the invention consists of a first electrode component and a second electrode component, wherein,
the first electrode assembly sequentially comprises from bottom to top:
the flexible printed circuit comprises a first flexible circuit substrate, a second flexible circuit substrate and a plurality of first conductive wires, wherein the first flexible circuit substrate is provided with a first electrode and at least one first annular external connection bonding pad, and the first electrode and the first annular external connection bonding pad are connected through a first lead;
the first insulating layer is provided with a first electrode groove;
a first insulating adhesive layer;
the second electrode component sequentially comprises from bottom to top:
the second flexible circuit substrate is provided with a second electrode and at least one second annular external connection bonding pad, and the second electrode and the second annular external connection bonding pad are connected through a second lead;
the second insulating layer is provided with a second electrode groove at the position corresponding to the first electrode groove;
a second insulating adhesive layer;
the first insulating layer, the first insulating bonding layer, the second insulating layer and the second insulating bonding layer are provided with pad holes at corresponding positions of the first annular external connection pad and the second annular external connection pad, the first flexible circuit substrate is provided with a pad hole at a corresponding position of the second annular external connection pad, and the second flexible circuit substrate is provided with a pad hole at a corresponding position of the first annular external connection pad;
the first electrode assembly and the second electrode assembly are adhered together through a second insulating adhesive layer.
Because the metal electrode is extremely fine, the metal electrode can be easily mixed by naked eye resolution; the enzyme is coated on the electrodes, and the joint of the two electrodes is easy to cause mutual pollution of the enzyme; by adopting the structure, the flexible blood sugar electrochemical test probe is divided into two electrode assemblies, so that the two electrodes can be separately processed and are assembled together after being respectively made into the assemblies, and the two electrodes can be effectively prevented from being assembled and polluted; and adopt the multilayer composite construction of flexible circuit base plate, the gross thickness does not exceed 1mm, can guarantee measurand's comfort.
The invention can be further realized by adopting the following technical scheme:
preferably, the number of the first annular external connection bonding pads is two; the number of the second annular external connection bonding pads is two.
Preferably, in the flexible blood glucose electrochemical test probe, a conductive member is disposed in the pad hole corresponding to at least one of the first annular external connection pad and the second annular external connection pad, so that the first electrode assembly and the second electrode assembly are electrically connected to the pad on the main control PCB.
Preferably, the first annular external connection pad and the second annular external connection pad are disposed on different sides of the first flexible circuit substrate and the second flexible circuit substrate.
Preferably, in the flexible blood glucose electrochemical test probe, a third insulating adhesive layer is further disposed on the lower end surface of the second flexible circuit substrate, and is used for fixing the flexible blood glucose electrochemical test probe on the main control PCB.
Preferably, the first insulating adhesive layer, the second insulating adhesive layer and the third insulating adhesive layer are insulating double-sided tapes.
Further, one end of the first lead is connected with the first annular external connection bonding pad, and the other end of the first lead is connected with the first electrode bonding pad; one end of the second lead is connected with the second annular external connection bonding pad, and the other end of the second lead is connected with the second electrode bonding pad; the first insulating layer is provided with a first window at a position corresponding to the first electrode pad, and the first window is used for arranging a conductive part so that the first electrode is conducted with the first electrode pad; and the second insulating layer is provided with a second window at the position corresponding to the second electrode pad, and the second window is used for arranging a conductive part so that the second electrode is conducted with the second electrode pad.
Preferably, in the flexible blood glucose electrochemical test probe, one of the first electrode and the second electrode is a working electrode, and the other is a reference electrode.
Preferably, the flexible blood glucose electrochemical test probe is characterized in that the first electrode and the second electrode are metal wire electrodes.
Preferably, the flexible blood glucose electrochemical test probe is characterized in that the conductive component is conductive adhesive, conductive rubber, conductive silver paste or copper nut.
The invention also provides an assembly method of the flexible blood glucose electrochemical test probe, which comprises the following steps:
s1: and assembling the first electrode assembly and the first electrode assembly respectively.
Wherein the first electrode assembly assembling process includes:
s11: adhering a first insulating layer to the first flexible circuit substrate;
s12: placing a first electrode into a first electrode groove, wherein the first electrode penetrates through two first windows on a first insulating layer;
s13: printing conductive adhesive in the two first windows on the first insulating layer to conduct the first electrodes with the two first electrode pads on the first flexible circuit substrate 11;
s14: and adhering the first insulating adhesive layer to the first insulating layer to complete the assembly of the first electrode assembly.
The second electrode assembly assembling process includes:
s21: adhering a second insulating layer to the second flexible circuit substrate;
s22: placing a second electrode into a second electrode groove, wherein the second electrode penetrates through two second windows on the second insulating layer;
s23: conductive adhesive is applied to the two second windows on the second insulating layer, and the second electrodes are conducted with the two second electrode pads on the second flexible circuit substrate;
s24: and adhering the second insulating adhesive layer to the second insulating layer to complete the assembly of the second electrode assembly.
S2: and adhering the assembled first electrode assembly and the second electrode assembly together by using a second insulating adhesive layer.
The method for assembling the flexible blood glucose electrochemical test probe comprises the steps of,
step S15 is also included after step S14: after the conductive adhesive on the first electrode assembly is completely cured, whether the two first annular external connection pads on the first flexible circuit substrate are conducted or not is measured, if the two first annular external connection pads are conducted, the first assembly is assembled to be qualified, step S2 can be performed, if the first assembly is opened, the problem in the assembly process of the first assembly is solved, and the assembly is scrapped.
The step further comprising, after the step S24, a step further comprising S25: after the conductive adhesive on the second electrode assembly is completely cured, whether the two second annular external connection pads on the second flexible circuit substrate are conducted or not is measured, if the two second annular external connection pads are conducted, the second assembly is assembled to be qualified, step S2 can be performed, if the second assembly is opened, the problem in the second assembly assembling process is solved, and the assembly is scrapped.
The method for assembling the flexible blood glucose electrochemical test probe comprises the steps of,
there is also step S3 between step S24 and step S2 or after step S2: and adhering a third insulating adhesion layer on the lower surface of the second flexible circuit substrate.
Further, the method for assembling the flexible blood glucose electrochemical test probe further includes the following steps after step S3:
s4: and fixing the flexible blood glucose electrochemical test probe on the main control PCB board by using a third insulating adhesive layer.
S5: and driving conductive adhesive into the pad holes corresponding to the at least one first annular external connection pad and the at least one second annular external connection pad, so that the first electrode assembly and the second electrode assembly are conducted with the pads on the main control PCB.
Compared with the prior art, the flexible blood sugar electrochemical test probe provided by the invention has the advantages that the comfort of a tested person is ensured, the stability and reliability of the probe are improved, the requirements on a production process and an assembly process are lower, and the realization of large-scale production and processing is facilitated.
Drawings
FIG. 1 is a schematic external view of a flexible electrochemical blood glucose test probe of the present invention;
FIG. 2 is a schematic view of the assembly of a flexible glycemic electrochemical test probe of the present invention;
FIG. 3 is a front view of a first insulating layer of the present invention;
FIG. 4 is a front view of a second insulating layer of the present invention;
FIG. 5 is a front view of a first flexible circuit substrate of the present invention;
fig. 6 is a front view of a second flexible circuit substrate of the present invention.
Detailed Description
The structure, features and effects of the present invention are described in detail below with reference to the accompanying drawings and preferred embodiments:
as shown in fig. 1 to 6, the present invention provides a flexible blood glucose electrochemical test probe, which is composed of a first electrode assembly 1 and a second electrode assembly 2, wherein,
the first electrode assembly 1 includes, from bottom to top:
the flexible printed circuit comprises a first flexible circuit substrate 11, wherein a first electrode 111 and at least one first annular external connection pad 112 are arranged on the first flexible circuit substrate, and the first electrode and the first annular external connection pad are connected through a first lead 113;
a first insulating layer 12, which is provided with a first electrode groove 121;
a first insulating adhesive layer 13;
the second electrode assembly 2 comprises from bottom to top in sequence:
a second flexible circuit substrate 21, on which a second electrode 211 and at least one second annular external bonding pad 212 are disposed, and the second electrode and the second annular external bonding pad are connected by a second wire 213;
a second insulating layer 22, wherein a second electrode groove 221 is formed in the second insulating layer at a position corresponding to the first electrode groove 121;
a second insulating adhesive layer 23;
the first insulating layer 12, the first insulating adhesive layer 13, the second insulating layer 22 and the second insulating adhesive layer 23 are provided with pad holes (122, 131, 222, 231) at positions corresponding to the first annular outer bonding pad 112 and the second annular outer bonding pad 212, the first flexible circuit substrate 11 is provided with a pad hole 114 at a position corresponding to the second annular outer bonding pad 212, and the second flexible circuit substrate 21 is provided with a pad hole 214 at a position corresponding to the first annular outer bonding pad 112;
the first electrode assembly 1 and the second electrode assembly 2 are adhered together through a second insulating adhesive layer 23.
Specifically, the first electrode 111 and the second electrode 211 respectively include a distal insertion portion for penetrating into the skin of the subject and a proximal retention portion for mounting with the electrode assembly, which are conventional in design and will not be described herein. The first electrode 111 is a working electrode, the second electrode 211 is a reference electrode, or the first electrode is a reference electrode and the second electrode is a working electrode. Preferably, the first electrode and the second electrode are metal wire electrodes.
Because the metal wire electrode is extremely fine, the metal wire electrode can be easily mixed by naked eye resolution; the enzyme is coated on the electrodes, and the joint of the two electrodes is easy to cause mutual pollution of the enzyme; by adopting the structure, the flexible blood sugar electrochemical test probe is divided into two electrode assemblies, so that the two electrodes can be separately processed and are assembled together after being respectively processed into independent assemblies, and the two electrodes can be effectively prevented from being assembled and polluted; the first electrode and the second electrode are limited by arranging the first electrode groove and the second electrode groove, so that the two electrodes can be ensured to be parallel in the shortest distance; and adopt the multilayer composite construction of flexible circuit base plate, the gross thickness does not exceed 1mm, has guaranteed the comfort of measurand.
This embodiment can be further realized by the following structure:
the aforementioned flexible blood glucose electrochemical test probe, wherein the number of the first annular external connection pads 112 is two; the number of the second ring-shaped outer bonding pads 212 is two.
Specifically, one end of the first wire 113 is connected to the first annular external connection pad 112, and the other end is connected to the first electrode pad 115; one end of the second wire 213 is connected to the second annular outer bonding pad 212, and the other end is connected to the second electrode bonding pad 215; the first insulating layer 12 has a first window 123 formed at a position corresponding to the first electrode pad 115, the second insulating layer 22 has a second window 223 formed at a position corresponding to the second electrode pad 215, and a conductive member (not shown) may be disposed in the first window and the second window, so that the first electrode 111 is in conduction with the first electrode pad 115 and the second electrode 211 is in conduction with the second electrode pad 215. The conductive component can be conductive adhesive, conductive rubber, conductive silver paste or copper nut; preferably, the double-component conductive adhesive can be selected.
After the first electrode assembly 1 is assembled, the first electrodes 111 are respectively conducted with the two first electrode pads 115 on the first flexible circuit substrate 11, and the two first electrode pads 115 are respectively conducted with the corresponding first annular external connection pads 112, so that whether the first electrodes are conducted with the first flexible circuit substrate can be determined by detecting whether the two first annular external connection pads are conducted.
Similarly, after the second electrode assembly 2 is assembled, the second electrodes 211 are respectively conducted with the two second electrode pads 215 on the second flexible circuit board 21, and the two second electrode pads 215 are respectively conducted with the corresponding second annular external connection pads 212, so that it is only necessary to detect whether the two second annular external connection pads are conducted to determine whether the second electrodes are conducted with the second flexible circuit board.
Therefore, by adopting the structure, the first electrode assembly and the second electrode assembly can be respectively subjected to continuity detection after the assembly is finished, the phenomena of circuit breaking and poor contact of the electrodes are avoided, the yield is improved, the stability and the reliability of the probe are improved, and the production cost is effectively reduced.
Preferably, the first and second annular outer bonding pads 112 and 212 are disposed on different sides of the first and second flexible circuit substrates 11 and 21. Short circuit caused by the close distance of the conducting wire area can be avoided.
The flexible blood glucose electrochemical test probe is characterized in that a conductive component (not shown) is arranged in the pad hole corresponding to at least one first annular external bonding pad 112 and at least one second annular external bonding pad 212, so that the first electrode assembly 1 and the second electrode assembly 2 are conducted with a pad (not shown) on a main control PCB (not shown). Preferably, the conductive parts are arranged in the pad holes corresponding to the two first annular external connection pads and the two second annular external connection pads, so that the two first annular external connection pads and the two second annular external connection pads are respectively conducted with the corresponding pads on the main control PCB. This prevents disconnection due to contact failure, vibration, or the like. The conductive component can be conductive adhesive, conductive rubber, conductive silver paste or copper nut; preferably, the double-component conductive adhesive can be selected.
Preferably, in the flexible blood glucose electrochemical test probe, a third insulating adhesive layer 24 is further disposed on the lower end surface of the second flexible circuit substrate 21, and is used to fix the flexible blood glucose electrochemical test probe on the main control PCB. The third insulating adhesive layer 23 has pad holes 241 formed at positions corresponding to the first annular outer bonding pad 112 and the second annular outer bonding pad 212.
Preferably, in the flexible blood glucose electrochemical test probe, the first insulating adhesive layer 13, the second insulating adhesive layer 23 and the third insulating adhesive layer 24 are insulating double-sided tapes.
Taking the example that two first annular external connection pads 112 and two second annular external connection pads 212 are respectively arranged, the assembling process of the flexible blood glucose electrochemical test probe of the invention comprises the following steps:
s1: the first electrode assembly 1 and the first electrode assembly 2 are assembled.
Wherein the first electrode assembly 1 assembling process includes:
s11: adhering the first insulating layer 12 to the first flexible circuit substrate 11;
s12: placing a first electrode 111, which penetrates through two first windows 123 on the first insulating layer 12, into the first electrode groove 121;
s13: printing conductive adhesive in the two first windows on the first insulating layer to connect the first electrode 111 with the two first electrode pads 115 on the first flexible circuit substrate 11;
s14: the first insulating adhesive layer 13 is adhered to the first insulating layer 12, and the first electrode assembly is completed.
In this embodiment, the method further includes S15: after the conductive paste on the first electrode assembly is completely cured, it is measured whether the two first annular external connection pads 112 on the first flexible circuit substrate are conducted, if so, the first assembly is assembled to be qualified, step S2 may be performed, and if so, it is determined that the first assembly is in a problem and the assembly is discarded.
The second electrode assembly assembling process includes:
s21: adhering the second insulating layer 22 to the second flexible circuit substrate 21;
s22: placing a second electrode 211 in a second electrode groove 221, the second electrode penetrating through two second windows 223 on the second insulating layer 22;
s23: coating conductive adhesive in the two second windows on the second insulating layer to connect the second electrode 211 with the two second electrode pads 215 on the second flexible circuit substrate 21;
s24: the second insulating adhesive layer 23 is adhered to the second insulating layer 22, and the second electrode assembly is completed.
In this embodiment, the method further includes S25: after the conductive adhesive on the second electrode assembly is completely cured, whether the two second annular outer bonding pads 212 on the second flexible circuit substrate are conducted or not is measured, if the two second annular outer bonding pads are conducted, the second assembly is assembled to be qualified, step S2 can be performed, if the two second annular outer bonding pads are open, the problem exists in the second assembly assembling process, and the assembly is discarded.
S2: the assembled first electrode assembly 1 and second electrode assembly 2 are adhered together with the second insulating adhesive layer 23.
In the present embodiment, there is a step S3 between step S24 and step S2 or after step S2: a third insulating adhesive layer 24 is adhered to the lower surface of the second flexible circuit board 21.
Further, the method also comprises the following steps:
s4: the flexible glycemic electrochemical test probe was secured to a master control PCB board (not shown) with a third insulating adhesive layer 24.
S5: and (3) driving conductive adhesive into the pad holes corresponding to at least one first annular outer bonding pad 112 and at least one second annular outer bonding pad 212, so that the first electrode assembly and the second electrode assembly are conducted with pads (not shown) on a main control PCB.
Compared with the prior art, the flexible blood sugar electrochemical test probe provided by the invention has the advantages that the comfort of a tested person is ensured, the stability and reliability of the probe are improved, the requirements on a production process and an assembly process are lower, and the realization of large-scale production and processing is facilitated.
The above description is only a preferred embodiment of the present invention, and any simple modifications and equivalent changes to the above embodiment according to the technical solution of the present invention are within the protection scope of the present invention.
Claims (14)
1. A flexible blood glucose electrochemical test probe is characterized by consisting of a first electrode component and a second electrode component,
the first electrode assembly sequentially comprises from bottom to top:
the flexible printed circuit comprises a first flexible circuit substrate, a second flexible circuit substrate and a plurality of first conductive wires, wherein the first flexible circuit substrate is provided with a first electrode and at least one first annular external connection bonding pad, and the first electrode and the first annular external connection bonding pad are connected through a first lead;
the first insulating layer is provided with a first electrode groove;
a first insulating adhesive layer;
the second electrode component sequentially comprises from bottom to top:
the second flexible circuit substrate is provided with a second electrode and at least one second annular external connection bonding pad, and the second electrode and the second annular external connection bonding pad are connected through a second lead;
the second insulating layer is provided with a second electrode groove at the position corresponding to the first electrode groove;
a second insulating adhesive layer;
the first insulating layer, the first insulating bonding layer, the second insulating layer and the second insulating bonding layer are provided with pad holes at corresponding positions of the first annular external connection pad and the second annular external connection pad, the first flexible circuit substrate is provided with a pad hole at a corresponding position of the second annular external connection pad, and the second flexible circuit substrate is provided with a pad hole at a corresponding position of the first annular external connection pad;
the first electrode assembly and the second electrode assembly are adhered together through a second insulating adhesive layer.
2. The flexible glycemic electrochemical test probe of claim 1, wherein the first annular outer bond pads are two in number; the number of the second annular external connection bonding pads is two.
3. The flexible glycemic electrochemical test probe of claim 2, wherein a conductive member is disposed in the pad hole corresponding to at least one of the first annular outer bonding pad and at least one of the second annular outer bonding pads, such that the first electrode assembly and the second electrode assembly are in electrical communication with a pad on a main control PCB.
4. The flexible glycemic electrochemical test probe of claim 2, wherein the first and second annular outer bond pads are disposed on different sides of the first and second flexible circuit substrates.
5. The flexible blood glucose electrochemical test probe of claim 1, wherein a third insulating adhesive layer is further disposed on the lower end surface of the second flexible circuit substrate for fixing the flexible blood glucose electrochemical test probe on a main control PCB.
6. The flexible glycemic electrochemical test probe of claim 5, wherein the first, second, and third insulating adhesive layers are insulating double sided tape.
7. The flexible glycemic electrochemical test probe of claim 1, wherein the first wire has one end connected to the first annular outer bond pad and the other end connected to the first electrode pad; one end of the second lead is connected with the second annular external connection bonding pad, and the other end of the second lead is connected with the second electrode bonding pad; the first insulating layer is provided with a first window at a position corresponding to the first electrode pad, and the first window is used for arranging a conductive part so that the first electrode is conducted with the first electrode pad; and the second insulating layer is provided with a second window at the position corresponding to the second electrode pad, and the second window is used for arranging a conductive part so that the second electrode is conducted with the second electrode pad.
8. The flexible glycemic electrochemical test probe of claim 1, wherein the first electrode, the second electrode, one of the first electrode and the second electrode is a working electrode and the other of the first electrode and the second electrode is a reference electrode.
9. The flexible glycemic electrochemical test probe of claim 1, wherein the first and second electrodes are wire electrodes.
10. The flexible glycemic electrochemical test probe of claim 3, 7, wherein the electrically conductive component is a conductive paste, a conductive rubber, a conductive silver paste, or a copper nut.
11. A method of assembling a flexible glycemic electrochemical test probe, comprising the steps of:
s1: assembling the first electrode assembly and the first electrode assembly respectively;
wherein the first electrode assembly assembling process includes:
s11: adhering a first insulating layer to the first flexible circuit substrate;
s12: placing a first electrode into a first electrode groove, wherein the first electrode penetrates through two first windows on a first insulating layer;
s13: printing conductive adhesive in the two first windows on the first insulating layer to conduct the first electrodes with the two first electrode pads on the first flexible circuit substrate;
s14: adhering a first insulating adhesive layer to the first insulating layer, and completing the assembly of the first electrode assembly;
the second electrode assembly assembling process includes:
s21: adhering a second insulating layer to the second flexible circuit substrate;
s22: placing a second electrode into a second electrode groove, wherein the second electrode penetrates through two second windows on the second insulating layer;
s23: conductive adhesive is applied to the two second windows on the second insulating layer, and the second electrodes are conducted with the two second electrode pads on the second flexible circuit substrate;
s24: adhering a second insulating adhesive layer to the second insulating layer to complete the assembly of the second electrode assembly;
s2: and adhering the assembled first electrode assembly and the second electrode assembly together by using a second insulating adhesive layer.
12. The method of assembling a flexible glycemic electrochemical test probe of claim 11,
step S15 is also included after step S14: after the conductive adhesive on the first electrode assembly is completely cured, measuring whether the two first annular external connection pads on the first flexible circuit substrate are conducted, if the two first annular external connection pads are conducted, the first assembly is assembled to be qualified, and performing step S2, if the two first annular external connection pads are conducted, the problem is caused in the assembly process of the first assembly, and the assembly is scrapped;
the step further comprising, after the step S24, a step further comprising S25: after the conductive adhesive on the second electrode assembly is completely cured, whether the two second annular external connection pads on the second flexible circuit substrate are conducted or not is measured, if the two second annular external connection pads are conducted, the second assembly is assembled to be qualified, step S2 can be performed, if the second assembly is opened, the problem in the second assembly assembling process is solved, and the assembly is scrapped.
13. The method of assembling a flexible glycemic electrochemical test probe of claim 12,
there is also step S3 between step S24 and step S2 or after step S2: and adhering a third insulating adhesion layer on the lower surface of the second flexible circuit substrate.
14. The method of assembling a flexible glycemic electrochemical test probe of claim 13, further comprising, after step S3, the steps of:
s4: fixing the flexible blood glucose electrochemical test probe on a main control PCB board by using a third insulating adhesive layer;
s5: and driving conductive adhesive into the pad holes corresponding to the at least one first annular external connection pad and the at least one second annular external connection pad, so that the first electrode assembly and the second electrode assembly are conducted with the pads on the main control PCB.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011386140.9A CN112294326A (en) | 2020-12-01 | 2020-12-01 | Flexible blood glucose electrochemical test probe and assembling method thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011386140.9A CN112294326A (en) | 2020-12-01 | 2020-12-01 | Flexible blood glucose electrochemical test probe and assembling method thereof |
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| CN112294326A true CN112294326A (en) | 2021-02-02 |
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| CN202011386140.9A Pending CN112294326A (en) | 2020-12-01 | 2020-12-01 | Flexible blood glucose electrochemical test probe and assembling method thereof |
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2020
- 2020-12-01 CN CN202011386140.9A patent/CN112294326A/en active Pending
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