CN112280672A - Efficient collagen peptide enzymolysis tank - Google Patents

Efficient collagen peptide enzymolysis tank Download PDF

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Publication number
CN112280672A
CN112280672A CN202011183531.0A CN202011183531A CN112280672A CN 112280672 A CN112280672 A CN 112280672A CN 202011183531 A CN202011183531 A CN 202011183531A CN 112280672 A CN112280672 A CN 112280672A
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Prior art keywords
plate
tank body
tank
partition plate
collagen peptide
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CN202011183531.0A
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Chinese (zh)
Inventor
张震豪
吴钰涛
林晓光
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Zhejiang Xinmei Biotechnology Co Ltd
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Zhejiang Xinmei Biotechnology Co Ltd
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Priority to CN202011183531.0A priority Critical patent/CN112280672A/en
Publication of CN112280672A publication Critical patent/CN112280672A/en
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M21/00Bioreactors or fermenters specially adapted for specific uses
    • C12M21/18Apparatus specially designed for the use of free, immobilized or carrier-bound enzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/34Internal compartments or partitions
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00Means for mixing, agitating or circulating fluids in the vessel
    • C12M27/18Flow directing inserts
    • C12M27/22Perforated plates, discs or walls
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M37/00Means for sterilizing, maintaining sterile conditions or avoiding chemical or biological contamination
    • C12M37/04Seals
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/12Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
    • C12M41/18Heat exchange systems, e.g. heat jackets or outer envelopes
    • C12M41/22Heat exchange systems, e.g. heat jackets or outer envelopes in contact with the bioreactor walls

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Sustainable Development (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Thermal Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

The invention discloses a collagen peptide high-efficiency enzymolysis tank which comprises a tank body, wherein a bottom plate is fixed at the lower part in the tank body, the lower part of the tank body is divided into inactivation cavities, a partition plate which can be adjusted up and down is arranged above the bottom plate in an inner cavity of the tank body and can divide the upper part of the bottom plate into two closed cavities, a diving electromagnetic valve is communicated with the bottom plate corresponding to the cavities, and sealing backup plates which are attached to the partition plate and are highly matched with the partition plate are fixed at the front and back of two end parts of the partition plate in a staggered manner. According to the efficient collagen peptide enzymolysis tank, the baffle capable of being lifted up and down is arranged in the tank body, so that solutions in the tank body can be separated for continuous operation, and the working efficiency is greatly improved; in addition, a scraping plate capable of scraping the wall is arranged in the tank body, so that the stirring of the glue solution in the tank body can be promoted.

Description

Efficient collagen peptide enzymolysis tank
Technical Field
The invention relates to the technical field of collagen peptide production and processing equipment, in particular to a collagen peptide high-efficiency enzymolysis tank.
Background
Collagen peptide is widely used in food, cosmetic and health care product industries, in the past, raw materials for preparing the collagen peptide mainly come from bones and skins of animals (such as cow leather, pigskin and fish skin), the collagen peptide can be converted into small molecular peptides by enzymolysis treatment in the production process, an enzyme solution and a glue solution are pumped into an enzymolysis reaction tank firstly, after a certain pH and temperature are maintained, the solution after reaction is heated and inactivated to obtain the solution after enzymolysis, and the solution after enzymolysis is pumped out for subsequent treatment.
Because the protein glue solution has high viscosity and is pumped into the enzymolysis tank, the traditional enzymolysis tank has poor mixing effect on the glue solution close to the tank wall, so that the glue solution around the tank wall has high concentration and is easy to adhere to the periphery of the tank wall and is not uniformly mixed with the enzyme solution in the enzymolysis and stirring process;
in addition, the traditional enzymolysis tank needs to adopt more than two tank bodies to carry out enzymolysis and enzyme deactivation treatment respectively, which undoubtedly increases the equipment cost investment.
Disclosure of Invention
The present invention is directed to solving, at least to some extent, one of the technical problems in the related art. Therefore, one purpose of the invention is to provide a collagen peptide high-efficiency enzymolysis tank, wherein a baffle plate capable of being lifted up and down is arranged in a tank body, so that the solution in the tank body can be separated for continuous operation, and the working efficiency is greatly increased; in addition, a scraping plate capable of scraping the wall is arranged in the tank body, so that the stirring of the glue solution in the tank body can be promoted.
The technical scheme of the invention is as follows:
the utility model provides a high-efficient enzymolysis tank of collagen peptide, includes a jar body, the internal lower part of jar is fixed with the bottom plate and separates into the deactivation chamber with jar body lower part the bottom plate top in jar internal intracavity be provided with the baffle that can adjust from top to bottom can separate into two confined cavities with the bottom plate top, and correspond on the bottom plate the cavity intercommunication has dive solenoid valve, just the sealed backup plate who misplaces around the baffle both ends is fixed with the laminating of baffle and high matching.
Furthermore, an air cylinder is arranged at the top of the tank body, a transmission shaft of the air cylinder is connected with the top of the partition plate, sealing rubber strips are fixed on the sealing contact surfaces of the partition plate and the sealing backup plate, and the sealing rubber strips can be directly glued and fixed; meanwhile, a sealing rubber strip is also fixed at the bottom of the partition plate.
Furthermore, the transmission shaft of the cylinder is rotatably connected with the top of the partition plate, and an electric push rod capable of pushing the partition plate towards the direction of the sealing backup plate is arranged on the top of the inner wall of the tank body corresponding to the partition plate.
Furthermore, driving shafts are respectively arranged in two chambers which are separated by the separating plate from the tank body, a scraping plate mechanism which can rotate in a reciprocating manner is fixed on the driving shafts, the scraping plate mechanism comprises a stirring plate and a scraping plate which can be self-adaptive and is attached to the wall surface of the tank body, and a plurality of through holes are formed in the stirring plate.
Furthermore, the one end that the stirring board is close to jar body wall corresponds the slip chamber has been seted up to the scraper blade be equipped with the spring through the installation sleeve on the inner wall in slip chamber and be used for supporting the scraper blade stretches into the one end in slip chamber for the scraper blade can promote the scraper blade when the spring resets and closely laminate jar body wall in the rotation in-process.
Furthermore, the outer sides of the two chambers separated by the tank body by the partition plate are respectively provided with a first heating jacket and a second heating jacket, and the outer side of the inactivation chamber is provided with a third heating jacket.
The invention has the following beneficial effects: by arranging the sealing backup plate and the baffle plate which can be adjusted up and down, the solution in the tank body can be divided into two parts; the partition plate which is rotatably connected with the partition plate is arranged and is matched with the electric push rod, so that the partition plate can be conveniently and tightly attached to the sealing backup plate, and meanwhile, when the partition plate needs to be lifted, the sealing backup plate can be separated from the partition plate only by retracting the transmission rod of the electric push rod, the sealing backup plate can be conveniently pulled up by the air cylinder, and the service life of a sealing element can be prolonged; by arranging the scraping mechanism, glue in the tank body can be conveniently mixed, so that the glue is not easy to adhere to the wall surface; through setting up three clamp covers, can control respectively carry out enzymolysis reaction, carry out the intensification heating before going out the enzyme to the enzyme liquid after the enzymolysis reaction and discharge the temperature of deactivation in the inactivation chamber through diving solenoid valve with the solution after preheating, because inactivation chamber volume is less relatively, and solution has been through preheating simultaneously, and the piece heaies up, therefore efficiency is higher.
Drawings
The accompanying drawings, which are included to provide a further understanding of the invention and are incorporated in and constitute a part of this specification, illustrate embodiments of the invention and together with the description serve to explain the principles of the invention and not to limit the invention. In the drawings:
FIG. 1 is a schematic structural diagram of a collagen peptide high-efficiency enzymolysis tank provided by the invention (related feeding pipelines are omitted);
FIG. 2 is a schematic top view of the structure of FIG. 1 (with the associated feed lines omitted);
fig. 3 is a schematic structural view of the squeegee mechanism.
In the figure: 1-tank body; 11-a base plate; 12-a submersible electromagnetic valve; 13-an inactivation chamber; 2-a separator; 21-an electric push rod; 3-a cylinder; 4-sealing the backup plate; 5-a drive shaft; 51-a stirring plate; 511-sliding chamber; 512-a spring; 52-a scraper; 61-a first heating jacket; 62-a second heating jacket; 63-third heating jacket.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments.
Examples of which are illustrated in the accompanying drawings, wherein like reference numerals refer to the same or similar elements or elements having the same or similar function throughout. The embodiments described below with reference to the drawings are illustrative and intended to be illustrative of the invention and are not to be construed as limiting the invention.
Example one
Referring to fig. 1, a high-efficient enzymolysis tank of collagen peptide, including a jar body 1, 1 internal lower part of jar is fixed with bottom plate 11 and separates into inactivation chamber 13 with jar body 1 lower part bottom plate 11 top in 1 internal intracavity of jar is provided with baffle 2 that can adjust from top to bottom and can separates into two confined cavities with bottom plate 11 top, and correspond on the bottom plate 11 the cavity intercommunication has dive solenoid valve 12 (product sold in the market), just the dislocation is fixed with the sealed backup plate 4 of laminating and highly matching with baffle 2 around the baffle 2 both ends.
A cylinder 3 is arranged at the top of the tank body 1, a transmission shaft of the cylinder 3 is connected with the top of the partition plate 2, sealing rubber strips are fixed on the sealing contact surfaces of the partition plate 2 and the sealing backup plate 4, and the sealing rubber strips can be directly glued and fixed; meanwhile, a sealing rubber strip is also fixed at the bottom of the partition board 2.
Example two
Referring to fig. 1-2, in order to facilitate the vertical adjustment of the partition board 2 and ensure the sealing reliability of the partition board 2, the transmission shaft of the cylinder 3 is rotatably connected to the top of the partition board 2, and an electric push rod 21 capable of pushing the partition board 2 towards the direction of the sealing backup plate 4 is arranged on the top of the inner wall of the tank 1 corresponding to the partition board 2.
Because baffle 2 and cylinder 3's transmission shaft rotatable coupling, cooperation electric push rod 21 can conveniently closely laminate sealed backup plate 4 with baffle 2, when need raising baffle 2 simultaneously, only need make electric push rod 21's transfer line withdraw, can make sealed backup plate 4 and baffle 2 separation, be convenient for by cylinder 3 pull-up, also can increase the life of sealing member.
EXAMPLE III
Further referring to fig. 1-3, in order to facilitate the scraping coating of the inner wall of the tank body 1, a driving shaft 5 is respectively arranged in two chambers separated by the partition board 2 from the tank body 1, and a scraping mechanism capable of reciprocating rotation is fixed on the driving shaft 5. The scraper mechanism comprises a stirring plate 51 and a scraper 52 which can be self-adaptive and is attached to the wall surface of the tank body, and a plurality of through holes are formed in the stirring plate 51, so that the flow is guided while stirring is performed, and the resistance is reduced.
As shown in fig. 3, a sliding cavity 511 is opened at one end of the stirring plate 51 close to the wall surface of the can body 1 corresponding to the scraper 52, a spring 512 is provided on the inner wall of the sliding cavity 511 through a mounting sleeve for abutting against one end of the scraper 52 extending into the sliding cavity 511, and the scraper 52 can push the scraper 52 to closely adhere to the wall surface of the can body when the spring 512 is reset in the rotating process.
In the drawings, a drive mechanism for driving the drive shaft 5, which is a commercially available motor that intermittently and bidirectionally rotates and a reduction gear, is omitted, and the drive shaft 5 is bidirectionally driven.
Example four
Referring to fig. 1 and 2, the baffle 2 is provided with first heating jacket 61 and second heating jacket 62 respectively with jar body 1 divided two cavity outsides, set up third heating jacket 63 in the inactivation chamber 13 outside simultaneously, and heat through steam, can be respectively through adjusting the temperature of three jackets, in order to satisfy carry out the enzymolysis, carry out the intensification heating before going out the enzyme to the enzyme solution after the enzymolysis, and discharge the solution after preheating into inactivation chamber 13 through dive solenoid valve 12 and further inactivate, because inactivation chamber volume is less relatively, solution has been through preheating simultaneously, the piece heaies up, therefore efficiency is higher.
After the solution in the chamber at one end of the upper part of the bottom plate 11 is drained, the solution to be subjected to enzymolysis reaction can be pumped in for heating and preheating, the solution in the other chamber is also discharged into the inactivation chamber until the inactivation is completely carried out, and after the solution is combusted, the partition plate 2 can be lifted to pump new enzyme liquid into the whole tank body and continue to pump the solution to be subjected to enzymolysis, so that the heat energy can be fully utilized.
In the present application, the structure and the connection relationship that are not described in detail are all the prior art, for example, the related detecting instrument and the inlet and outlet pipeline for the raw material, the structure and the principle thereof are known in the prior art, and are not described herein again.
The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be considered to be within the technical scope of the present invention, and the technical solutions and the inventive concepts thereof according to the present invention should be equivalent or changed within the scope of the present invention.

Claims (6)

1. The utility model provides a high-efficient enzymolysis tank of collagen peptide which characterized in that: including a jar body, the internal lower part of jar is fixed with the bottom plate and separates into the deactivation chamber with jar body lower part the bottom plate top in the internal intracavity of jar is provided with the baffle that can adjust from top to bottom and can separates into two confined cavities with the bottom plate top, and correspond on the bottom plate the cavity intercommunication has dive solenoid valve, just the dislocation is fixed with around the baffle both ends with the sealed backup plate of baffle laminating and high matching.
2. The efficient collagen peptide enzymolysis tank of claim 1, which is characterized in that: a cylinder is arranged at the top of the tank body, a transmission shaft of the cylinder is connected with the top of the partition plate, sealing rubber strips are fixed on the sealing contact surfaces of the partition plate and the sealing backup plate, and the sealing rubber strips can be directly glued and fixed; meanwhile, a sealing rubber strip is also fixed at the bottom of the partition plate.
3. The efficient collagen peptide enzymolysis tank of claim 2, which is characterized in that: the transmission shaft of the cylinder is rotatably connected with the top of the partition plate, and an electric push rod capable of pushing the partition plate towards the direction of the sealing backup plate is arranged on the top of the inner wall of the tank body corresponding to the partition plate.
4. The tank for highly efficient enzymatic hydrolysis of collagen peptides according to any one of claims 1 to 3, wherein: the tank body is characterized in that driving shafts are respectively arranged in two chambers which are separated by the partition board, a scraping plate mechanism capable of rotating in a reciprocating mode is fixed on each driving shaft, each scraping plate mechanism comprises a stirring plate and a scraping plate capable of adapting to the wall surface of the tank body in a self-adaptive mode, and a plurality of through holes are formed in the stirring plate.
5. The efficient collagen peptide enzymolysis tank of claim 4, wherein: the one end that the stirring board is close to jar body wall corresponds the slip chamber has been seted up to the scraper blade be equipped with the spring through the installation sleeve on the inner wall in slip chamber and be used for supporting the scraper blade stretches into the one end in slip chamber for the scraper blade can promote the scraper blade when the spring resets and closely laminate jar body wall rotating the in-process.
6. The tank for highly efficient enzymatic hydrolysis of collagen peptide according to any one of claims 1 to 3 and 5, wherein: the outer sides of the two chambers separated by the tank body by the partition plate are respectively provided with a first heating jacket and a second heating jacket, and the outer side of the inactivation chamber is provided with a third heating jacket.
CN202011183531.0A 2020-10-29 2020-10-29 Efficient collagen peptide enzymolysis tank Pending CN112280672A (en)

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Application Number Priority Date Filing Date Title
CN202011183531.0A CN112280672A (en) 2020-10-29 2020-10-29 Efficient collagen peptide enzymolysis tank

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113652462A (en) * 2021-08-20 2021-11-16 青岛万图明生物制品有限公司 Novel reation kettle is used for collagen peptide to prepare equipment
CN116574605A (en) * 2023-05-23 2023-08-11 青岛浩大生物科技工程有限责任公司 Collagen peptide efficient enzymolysis tank

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4543978A (en) * 1983-07-25 1985-10-01 Chicago Bridge & Iron Company Single tank for dual thermal energy storage with internal movable partition
WO1993022418A1 (en) * 1992-04-28 1993-11-11 Pirtferm Limited Bioreactor system
KR200381841Y1 (en) * 2005-01-31 2005-04-18 (주)동명기술공단종합건축사사무소 Variable partition of reactor for advanced treatment
RU2011150342A (en) * 2011-12-09 2013-06-20 Владимир Николаевич Кононов CAPACITY BIORACTOR
CN104437294A (en) * 2014-12-11 2015-03-25 重庆欣欣向荣精细化工有限公司 Adjustable chemical reaction kettle
CN208577563U (en) * 2018-05-07 2019-03-05 泉州康馨专利应用服务有限公司 A kind of sewage-treatment plant of heavy metal ion
CN210645212U (en) * 2019-08-12 2020-06-02 云南金柯制药有限公司 Processingequipment is used in fibrauretine extraction
CN210751656U (en) * 2019-09-05 2020-06-16 南京永正生物科技有限公司 Enzyme preparation is gunbarrel for microcapsule preparation

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4543978A (en) * 1983-07-25 1985-10-01 Chicago Bridge & Iron Company Single tank for dual thermal energy storage with internal movable partition
WO1993022418A1 (en) * 1992-04-28 1993-11-11 Pirtferm Limited Bioreactor system
KR200381841Y1 (en) * 2005-01-31 2005-04-18 (주)동명기술공단종합건축사사무소 Variable partition of reactor for advanced treatment
RU2011150342A (en) * 2011-12-09 2013-06-20 Владимир Николаевич Кононов CAPACITY BIORACTOR
CN104437294A (en) * 2014-12-11 2015-03-25 重庆欣欣向荣精细化工有限公司 Adjustable chemical reaction kettle
CN208577563U (en) * 2018-05-07 2019-03-05 泉州康馨专利应用服务有限公司 A kind of sewage-treatment plant of heavy metal ion
CN210645212U (en) * 2019-08-12 2020-06-02 云南金柯制药有限公司 Processingequipment is used in fibrauretine extraction
CN210751656U (en) * 2019-09-05 2020-06-16 南京永正生物科技有限公司 Enzyme preparation is gunbarrel for microcapsule preparation

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113652462A (en) * 2021-08-20 2021-11-16 青岛万图明生物制品有限公司 Novel reation kettle is used for collagen peptide to prepare equipment
CN116574605A (en) * 2023-05-23 2023-08-11 青岛浩大生物科技工程有限责任公司 Collagen peptide efficient enzymolysis tank
CN116574605B (en) * 2023-05-23 2024-04-19 青岛浩大海洋生物科技股份有限公司 Collagen peptide efficient enzymolysis tank

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