CN112220780A - Skin-friendly low-irritation plaster and preparation method thereof - Google Patents

Skin-friendly low-irritation plaster and preparation method thereof Download PDF

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Publication number
CN112220780A
CN112220780A CN202011313052.6A CN202011313052A CN112220780A CN 112220780 A CN112220780 A CN 112220780A CN 202011313052 A CN202011313052 A CN 202011313052A CN 112220780 A CN112220780 A CN 112220780A
Authority
CN
China
Prior art keywords
skin
layer
glue
irritation
adhesive layer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202011313052.6A
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Chinese (zh)
Inventor
李洪增
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN202011313052.6A priority Critical patent/CN112220780A/en
Publication of CN112220780A publication Critical patent/CN112220780A/en
Priority to CN202111371945.0A priority patent/CN114053250A/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7069Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Abstract

The invention discloses a skin-friendly low-irritation plaster and a manufacturing method thereof, and the skin-friendly low-irritation plaster comprises a tough bottom plate layer, a flexible adhesive layer and a release film, wherein the bottom plate layer is attached to the adhesive layer through static electricity, a glue layer is arranged on one surface of the adhesive layer, which is far away from the bottom plate layer, and the release film covers the surface of the glue layer; the bottom plate layer selects the PET material for use, and the rubberizing layer selects the TPU material for use, selects the PE material for use from the type membrane, and the main component of glue in the glue layer is dimethyl silicon oil. After the adhesive is adhered to the skin, the adhesive can be easily torn off, and cannot damage the skin. Meanwhile, the dimethyl silicone oil has certain lubrication and moisture retention effects on the skin, and can protect the skin at the adhered position. The invention has good skin-friendly property, can not damage the skin, and is particularly suitable for children with delicate skin and the old with loose skin and lack of elasticity.

Description

Skin-friendly low-irritation plaster and preparation method thereof
Technical Field
The invention relates to the field of medical supplies, in particular to a skin-friendly low-irritation plaster and a manufacturing method thereof.
Background
The plaster is a common external use medicine, traditionally vegetable oil or animal oil is added with medicine and decocted into colloidal substance, and the colloidal substance is coated on one surface of cloth, paper or skin, can be pasted on an affected part for a long time, and is mainly used for treating sore furuncle, detumescence and pain relief or diseases in bone and joint aspects.
With the development of technology, in order to achieve the purpose of sterility and cost saving, the prior art generally uses a way of coating glue on non-woven fabric to make a plaster. However, the existing plaster is too tightly attached to the skin after being stuck on the skin. If the skin is delicate (such as children's skin) or the skin is damaged, the patch is often torn off from the skin, which often causes damage to the skin by adhering the surface layer of the skin together.
Therefore, there is a need for a patch that is skin friendly, less irritating to the skin, and easy to attach and remove.
Disclosure of Invention
The invention aims to overcome the problems and provide a skin-friendly plaster with low irritation and a manufacturing method thereof. In order to achieve the purpose, the invention adopts the following technical scheme:
a skin-friendly low-irritation plaster comprises a tough bottom plate layer, a flexible adhesive layer and a release film, wherein the bottom plate layer and the adhesive layer are attached through static electricity, a glue layer is arranged on one surface of the adhesive layer, which is far away from the bottom plate layer, and the release film covers the surface of the glue layer;
the base plate layer selects the PET material for use, the rubberizing layer selects the TPU material for use, it selects the PE material for use to leave the type membrane, the main component of glue in the glue layer is dimethyl silicon oil.
The invention also discloses a manufacturing method of the skin-friendly low-irritation plaster, which comprises the following steps:
s1, adhering a glue layer to a bottom plate through static electricity;
s2, coating glue on the surface of the adhesive layer;
s3, curing the glue layer at high temperature to reduce the fluidity of the glue layer;
s4, covering a release film on the glue layer;
s5, die cutting is carried out on the manufactured plaster.
As an improvement, an opening convenient to tear is arranged in the middle of the release film, and the release film is divided into two pieces by the opening.
As an improvement, the surface of the adhesive layer is provided with air holes.
As an improvement, a medicine layer is further arranged on the surface of the glue layer.
As a modification, the coating amount of the glue in S2 is 120 g per square meter.
In the step S4, air holes are drilled in advance on the surface of the adhesive layer before the release film is covered.
The invention has the advantages that:
the adhesive layer is made of TPU material, is soft, has good skin-friendly property and low irritation to skin; the bottom plate layer is made of PET material, is slightly hard and tough, and mainly plays a supporting role when the adhesive layer is stored; the main component of the glue in the glue layer is dimethyl silicone oil, which has good skin-friendly effect, low grade to skin and moderate adhesion; after being adhered on the skin, the adhesive can be easily torn off without causing damage to the skin. Meanwhile, the dimethyl silicone oil has certain lubrication and moisture retention effects on the skin, and can protect the skin at the adhered position. The invention has good skin-friendly property, can not damage the skin, and is particularly suitable for children with delicate skin and the old with loose skin and lack of elasticity.
Drawings
FIG. 1 is a structural view of a skin-friendly low-irritation patch of example 1;
FIG. 2 is a structural view of an adhesive layer of a skin-friendly, low-irritation plaster in example 1;
fig. 3 is a cross-sectional view of a skin-friendly, low-irritation patch of example 1.
The labels in the figures illustrate:
1-bottom plate layer, 2-adhesive layer, 21-air vent, 3-release film, 31-opening, 4-glue layer and 5-medicine layer.
Detailed Description
The present invention will be described in detail and specifically with reference to the following examples so as to facilitate the understanding of the present invention, but the following examples do not limit the scope of the present invention.
Example 1
The embodiment discloses a skin-friendly low-irritation plaster, which comprises a tough bottom plate layer 1, a flexible adhesive layer 2 and a release film 3. The bottom plate layer 1 passes through the static laminating with the veneer layer 2, and veneer layer 2 keeps away from 1 one side of bottom plate layer and is equipped with glue layer 4, covers on 4 surfaces of glue layer from type membrane 3.
The bottom plate layer 1 is made of PET material and has the thickness of 0.036 cm; the adhesive layer 2 is made of TPU material, and the thickness is 0.025 cm; the release film 3 is made of PE material and has a thickness of 0.1 cm. The main component of the glue in the glue layer 4 is dimethyl silicone oil.
An opening 31 convenient for tearing is arranged in the middle of the release film 3, and the opening 31 divides the release film 3 into a two-piece structure. The surface of the adhesive layer 2 is provided with air holes 21. The surface of the glue layer 4 is also provided with a medicine layer 5.
The manufacturing method of the embodiment comprises the following steps:
s1, adhering a glue layer to a bottom plate through static electricity;
s2, coating glue on the surface of the adhesive layer, wherein the coating amount of the glue is 120 g less than square meter;
s3, curing the glue layer at high temperature to reduce the fluidity of the glue layer;
s4, drilling air holes in the surface of the adhesive layer, and covering a release film on the adhesive layer;
s5, die cutting is carried out on the manufactured plaster.
When the invention is used, the release film 3 is firstly torn off through the opening 31, and the glue layer 4 leaks out. Then, the drug layer 5 is applied to the affected part, and the plaster is applied to the skin. The backsheet layer 1 is then peeled off leaving only the soft, skin-friendly adhesive 2. The invention has good skin-friendly effect, does not damage skin after being adhered and torn off, and has good market popularization value.
The embodiments of the present invention have been described in detail above, but they are merely exemplary, and the present invention is not equivalent to the above described embodiments. Any equivalent modifications and substitutions to those skilled in the art are also within the scope of the present invention. Accordingly, it is intended that all equivalent alterations and modifications be included within the scope of the invention, without departing from the spirit and scope of the invention.

Claims (7)

1. The skin-friendly low-irritation plaster is characterized by comprising a tough bottom plate layer, a flexible adhesive layer and a release film, wherein the bottom plate layer and the adhesive layer are attached through static electricity, an adhesive layer is arranged on one surface of the adhesive layer, which is far away from the bottom plate layer, and the release film covers the surface of the adhesive layer;
the base plate layer selects the PET material for use, the rubberizing layer selects the TPU material for use, it selects the PE material for use to leave the type membrane, the main component of glue in the glue layer is dimethyl silicon oil.
2. The skin-friendly low-irritation plaster according to claim 1, wherein the release film is provided with an opening at the center thereof for easy tearing, and the opening divides the release film into two pieces.
3. The skin-friendly low-irritation plaster according to claim 1, wherein the surface of the adhesive layer is provided with air holes.
4. The skin-friendly low-irritation plaster according to claim 1, wherein a drug layer is further disposed on the surface of the glue layer.
5. A method of making a skin friendly, low irritation patch according to claim 1, comprising the steps of:
s1, adhering a glue layer to a bottom plate through static electricity;
s2, coating glue on the surface of the adhesive layer;
s3, curing the glue layer at high temperature to reduce the fluidity of the glue layer;
s4, covering a release film on the glue layer;
s5, die cutting is carried out on the manufactured plaster.
6. The method of claim 5 wherein the glue is applied at a rate of 120 grams per square meter of the patch at S2.
7. The method for manufacturing a skin-friendly low-irritation patch according to claims 3 and 5, wherein in the step S4, air holes are drilled in the surface of the adhesive layer before the release film is coated.
CN202011313052.6A 2020-11-20 2020-11-20 Skin-friendly low-irritation plaster and preparation method thereof Pending CN112220780A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CN202011313052.6A CN112220780A (en) 2020-11-20 2020-11-20 Skin-friendly low-irritation plaster and preparation method thereof
CN202111371945.0A CN114053250A (en) 2020-11-20 2021-11-18 Skin-friendly low-irritation plaster and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202011313052.6A CN112220780A (en) 2020-11-20 2020-11-20 Skin-friendly low-irritation plaster and preparation method thereof

Publications (1)

Publication Number Publication Date
CN112220780A true CN112220780A (en) 2021-01-15

Family

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Family Applications (2)

Application Number Title Priority Date Filing Date
CN202011313052.6A Pending CN112220780A (en) 2020-11-20 2020-11-20 Skin-friendly low-irritation plaster and preparation method thereof
CN202111371945.0A Withdrawn CN114053250A (en) 2020-11-20 2021-11-18 Skin-friendly low-irritation plaster and preparation method thereof

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN202111371945.0A Withdrawn CN114053250A (en) 2020-11-20 2021-11-18 Skin-friendly low-irritation plaster and preparation method thereof

Country Status (1)

Country Link
CN (2) CN112220780A (en)

Also Published As

Publication number Publication date
CN114053250A (en) 2022-02-18

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Application publication date: 20210115