CN112206021A

CN112206021A - Intervention type remote suture locking device

Info

Publication number: CN112206021A
Application number: CN201910622453.0A
Authority: CN
Inventors: 李阳; 郑贤章; 张伟伟; 张庭超
Original assignee: Hangzhou Valgen Medtech Co Ltd
Current assignee: Hangzhou Valgen Medtech Co Ltd
Priority date: 2019-07-10
Filing date: 2019-07-10
Publication date: 2021-01-12

Abstract

The invention provides an intervention type remote suture locking device which is used for locking a suture and a locking nail, and comprises a chuck component, wherein a gap for placing the locking nail is arranged at the far end of the chuck component, a threading cavity is axially arranged on the locking nail, a threading channel is axially arranged on the chuck component, the suture penetrates through the threading cavity and the threading channel of the locking nail, and the chuck component extrudes the locking nail to deform the locking nail so as to fix the suture. When the intervention type remote suture locking device is used, a suture is always contained in the threading channel, so that an included angle cannot be formed between the suture and a conveying system when the suture is tensioned, and the suture is prevented from tearing a puncture hole.

Description

Intervention type remote suture locking device

Technical Field

The invention relates to the technical field of medical instruments, in particular to an intervention type remote suture locking device.

Background

The operation of knotting and fixing suture is often required in the operation, and the traditional surgical operation is operated under the condition of open vision, and the knotting is usually carried out manually by a doctor. However, with the advance of technology, various minimally invasive and interventional procedures, such as laparoscopic procedures, transcatheter interventional procedures, etc., are becoming more common, which require a small operating window to be cut in the patient's body, whereby an instrument, such as an endoscope or interventional catheter, is inserted into the patient's body to a predetermined site for treatment. In such procedures, tying or securing sutures in the patient's body often requires the operator to remotely manipulate the sutures outside the patient's body through a small manipulation window.

The prior art discloses a suture locking device, adopts the side opening to draw forth the suture mode, however, when this kind of suture locking device was used for intervention formula remote operation's locking process, because intervention formula operation needs the distal end of device to be in the bending state, when taking up or tightening up the suture from the near-end under the state of turning round, the suture that the side opening was drawn forth probably leads to the suture to tear the puncture hole, not only can't guarantee the effect of locking, probably causes patient's serious damage even.

Disclosure of Invention

The technical problem to be solved by the present invention is to provide an intervention type remote suture locking device for preventing suture from tearing puncture, aiming at the defects of the prior art.

In order to solve the technical problem, the invention firstly provides an intervention type remote suture locking device which comprises a chuck component, wherein a gap for placing a locking nail is arranged at the far end of the chuck component, a threading cavity is axially arranged on the locking nail, a threading channel is axially arranged on the chuck component, the suture penetrates through the threading cavity of the locking nail and the threading channel, and the chuck component extrudes the locking nail to deform the locking nail so as to fix the suture.

When the intervention type remote suture locking device is used, the suture is always contained in the threading channel, so that an included angle cannot be formed between the suture and a conveying system when the suture is tensioned, and the suture is prevented from tearing a puncture hole.

Drawings

In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings needed to be used in the embodiments will be briefly described below, and it is obvious that the drawings in the following description are some embodiments of the present invention, and it is obvious for those skilled in the art to obtain other drawings based on these drawings without creative efforts.

Fig. 1 is a schematic perspective view of an interventional remote suture locking device according to a first embodiment of the present invention.

Fig. 2 is a sectional view taken along line II-II in fig. 1.

Fig. 3 is an enlarged view of the portion III in fig. 2.

Fig. 4 is a schematic perspective view of a staple compressed by a collet assembly of an interventional remote suture fastening device according to a first embodiment of the present invention.

Fig. 5 is a cross-sectional view of the locking pin of fig. 4.

Fig. 6 is a perspective view of a cartridge assembly of the interventional remote suture keying device of fig. 2.

Figure 7 is an exploded perspective view of the cartridge assembly of figure 6.

Fig. 8 is a perspective view of another perspective of the first collet of the collet assembly of fig. 7.

Fig. 9 is a side schematic view of the first collet of fig. 8.

Fig. 10 is a perspective view of another perspective view of the second collet of the collet assembly of fig. 7.

Fig. 11 is a side view of the second collet of fig. 10.

Figure 12 is a perspective view of the cartridge assembly of figure 6 from another perspective.

Fig. 13-14 are schematic views of two different states of a jaw assembly of an interventional remote suture keying device provided in accordance with a first embodiment of the present invention.

Fig. 15 is a perspective view of a drive assembly of the interventional remote suture keying device of fig. 3.

Fig. 16 is an exploded perspective view of the drive assembly of fig. 15.

Fig. 17 is a perspective view of the pin member of the driving assembly of fig. 16.

Fig. 18 is a cross-sectional view of the pin member of fig. 17.

Fig. 19 is a cross-sectional view of the screw of fig. 16.

Fig. 20 is a cross-sectional view of the connecting rod pin of fig. 16.

Fig. 21 is a sectional view taken along line XXI-XXI in fig. 15.

Fig. 22 is a perspective view of a push assembly of the interventional remote suture keying device of fig. 3.

Fig. 23 is an exploded perspective view of the pusher assembly of fig. 22.

Figure 24 is a cross-sectional view of the thrust tube of figure 23.

Figure 25 is a side view of the front end outer tube of the pusher assembly of figure 23.

Fig. 26 is a cross-sectional view of the leading end outer tube of fig. 25.

Fig. 27 is a perspective view of an alternate perspective of the end cap of the pusher assembly of fig. 23.

Fig. 28 is a cross-sectional view of the end cap of fig. 27.

Fig. 29 is a sectional view taken along line XXIX-XXIX in fig. 22.

Fig. 30 is an assembled partial cross-sectional view of the cartridge assembly, drive assembly and pusher assembly of the interventional remote suture locking device provided in accordance with the first embodiment of the present invention.

Fig. 31-33 are schematic views of the interventional remote suture locking device for valve repair of a diseased mitral valve according to the first embodiment of the present invention.

Fig. 34-35 are schematic views of the process for securing suture to a staple of the interventional remote suture locking device according to the first embodiment of the present invention.

Fig. 36 is an enlarged view of the XXXVI portion in fig. 33.

Fig. 37 is a schematic structural diagram of an interventional remote suture locking device according to a second embodiment of the present invention.

Fig. 38 is a perspective view of a first jaw of a jaw assembly of the interventional remote suture keying device of fig. 37.

Fig. 39 is a perspective view of a shaft of a cartridge assembly of the interventional remote suture keying device of fig. 37.

Fig. 40-41 are schematic views of the process for securing suture to a staple of an interventional remote suture locking device according to a second embodiment of the present invention.

Fig. 42 is a schematic structural diagram of an interventional remote suture locking device according to a third embodiment of the present invention.

Fig. 43 is a perspective view of a screw of a drive assembly of the interventional remote suture keying device of fig. 42.

Fig. 44 is a cross-sectional view of the screw of fig. 43.

Fig. 45 is a perspective view of a top bar member of the drive assembly of the interventional remote suture keying device of fig. 42.

Fig. 46-47 are schematic views of the process for securing suture to a staple of an interventional remote suture locking device according to a third embodiment of the present invention.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without any inventive step, are within the scope of the present invention.

Furthermore, the following description of the various embodiments refers to the accompanying drawings, which illustrate specific embodiments in which the invention may be practiced. Directional phrases used in this disclosure, such as, for example, "upper," "lower," "front," "rear," "left," "right," "inner," "outer," "side," and the like, refer only to the orientation of the appended drawings and are, therefore, used herein for better and clearer illustration and understanding of the invention, and do not indicate or imply that the device or element so referred to must have a particular orientation, be constructed and operated in a particular orientation, and are therefore not to be considered limiting of the invention.

Orientation definition: for clarity of description, the end of the surgical procedure that is closer to the operator will be referred to hereinafter as the "proximal end" and the end that is further from the operator will be referred to hereinafter as the "distal end"; the axial direction is parallel to the direction of the connection line of the center of the far end and the center of the near end of the medical instrument; the foregoing definitions are for convenience only and are not to be construed as limiting the present invention.

Referring to fig. 1 to 3, the present invention provides an intervention type remote suture locking device 100 for locking a suture and a locking nail 300, wherein the intervention type remote suture locking device 100 includes a collet assembly 20, a driving assembly 40 disposed at a proximal end of the collet assembly 20, and a pushing assembly 60 sleeved outside the collet assembly 20 and the driving assembly 40. The distal end of the cartridge assembly 20 is provided with a gap 25 for placing the locking nail 300, the locking nail 300 is provided with a threading cavity 301 along the axial direction, the intervention type remote suture locking device 100 is provided with a threading channel 26 passing through the cartridge assembly 20 and the driving assembly 40 along the axial direction, the suture is arranged in the threading cavity 301 of the locking nail 300 and the threading channel 26, the driving assembly 40 rotates relative to the pushing assembly 60 and moves along the axial direction to push against the cartridge assembly 20, so as to press the locking nail 300 placed in the gap 25, and the locking nail 300 is deformed to fix the suture. Because the suture is always contained in the threading channel 26 in the use process of the intervention type remote suture locking and knot device 100, when the suture is tensioned, an included angle is not formed between the suture and the tube body of the locking and knot device, and the suture is prevented from being cut off by a suture outlet on the tube body and from tearing a puncture hole.

The interventional remote suture locking device 100 also includes a handle 80 connected to the proximal end of the drive assembly 40 and the proximal end of the pusher assembly 60. The handle 80 includes a fixed portion 82 at a distal end and a movable portion 84 at a proximal end and capable of moving relative to the fixed portion 82, the fixed portion 82 is fixedly connected to the proximal end of the pushing assembly 60, the movable portion 84 is connected to the proximal end of the driving assembly 40, and the driving assembly 40 is driven to move axially relative to the pushing assembly 60 by the relative movement between the movable portion 84 and the fixed portion 82. Specifically, the movable portion 84 and the fixed portion 82 are capable of rotating and moving axially relative to each other, so as to drive the driving component 40 to rotate and move axially relative to the pushing component 60, and when the driving component 40 moves axially and distally to push against the chuck component 20, the locking pin 300 disposed in the gap 25 can be pressed, so as to complete the fixation of the suture and the locking pin 300.

Referring to fig. 4 and 5, the threading cavity 301 of the locking nail 300 axially penetrates through two opposite ends of the locking nail 300, and the threading cavity 301 is used for accommodating and passing a suture. The locking pin 300 can be collapsed when subjected to mechanical external forces to secure the suture in the threading lumen 301 of the locking pin 300. The locking pin 300 may be of various shapes, e.g., cylindrical, prismatic, oval, etc., so long as it has a threaded cavity 301 for receiving a suture. In this embodiment, the locking pin 300 is formed in a hollow cylindrical shape to reduce the resistance to pressure and to prevent scratching of human tissue. The outer wall of the distal end of the locking nail 300 is provided with an annular truncated cone 303 in a protruding mode in the radial direction. The distal opening of the threading lumen 301 of the locking nail 300 smoothly transitions with the distal surface of the locking nail 300 to avoid the junction therebetween cutting the suture or scratching the internal tissue of the patient. Specifically, an arc-shaped transition surface 305 is provided between the distal opening of threading lumen 301 and the distal surface of locking pin 300. The locking pin 300 is made of a biocompatible material such as stainless steel, pure titanium, nickel titanium, cobalt chromium alloy, and preferably pure titanium or stainless steel.

In other embodiments, in order to improve the coupling force between the crimped nail 300 and the suture, at least one pair of interlocking structures may be disposed in the threading cavity 301 of the nail 300, for example, a convex locking platform and a concave locking hole may be disposed at two positions opposite to the threading cavity 301, when the nail 300 is subjected to external crimping force and begins to deform, the convex locking platform is pressed into the concave locking hole, and when the nail 300 continues to deform, the locking platform and the locking hole are simultaneously deformed until they cannot be separated, and at this time, the suture is firmly fixed in the threading cavity 301 of the nail 300.

In order to improve the coupling force between the crimped lock pin 300 and the suture, an anti-slip structure may be further provided on the inner circumferential surface of the threading cavity 301, for example, an anti-slip pattern or a roughening treatment may be provided on the inner circumferential surface of the threading cavity 301, so that after the lock pin 300 is deformed by external crimping force, the friction force between the suture and the inner circumferential surface of the threading cavity 301 is increased, and the suture is more firmly fixed in the threading cavity 301 of the lock pin 300.

The jaw assembly 20 includes a first jaw 22 and a second jaw 24 connected or integrally formed with each other, and the connection between the first jaw 22 and the second jaw 24 communicates with a threading channel 26. A gap 25 is formed between the distal end of the first collet 22 and the distal end of the second collet 24, and when the driving member 40 rotates relative to the pushing member 60 and moves axially to push the first collet 22 and the second collet 24 of the collet assembly 20 to rotate towards each other, the first collet 22 and the second collet 24 can press the locking pin 300, so that the locking pin 300 is deformed and fixed to the suture.

In this embodiment, the proximal end of the first clamping head 22 is rotatably connected to the proximal end of the second clamping head 24 by a shaft 27, and the shaft 27 defines a through hole 271 communicating with the threading channel 26.

Opposite ends of the shaft 27 may be connected to the pusher assembly 60. A shaft 27 is fixed to the proximal end of second chuck 24 or first chuck 22, and accordingly, the proximal end of first chuck 22 or second chuck 24 is rotatably coupled to shaft 27.

Referring to fig. 6 to 13, the first clamping head 22 includes a first clamping piece 221 and a connecting hook 223 disposed at a middle portion of a proximal end of the first clamping piece 221. The coupling hook 223 is provided with a shaft hole 224 in an axial direction perpendicular to the interventional remote suture locking device 100, the rotation shaft 27 is received in the shaft hole 224, and the coupling hook 223 rotates along the rotation shaft 27. The proximal end of the first clamping head 22 is axially provided with a threading hole 225, and the threading hole 225 is communicated with the threading channel 26. In this embodiment, the wire passing hole 225 is opened on the connecting hook 223, and the wire passing hole 225 penetrates through the shaft hole 224 and the gap between the connecting hook 223 and the first clip 221. The side of first jaw 22 facing away from second jaw 24 is provided with a sloped slide guide surface 226, and slide guide surface 226 is located at the distal end of first jaw 22 and extends obliquely towards the side facing away from threading channel 26. Specifically, the thickness of the distal end of the first clip piece 221 is greater than the thickness of the proximal end, a protrusion is formed on the distal end of the first clip piece 221, and the sliding guide surface 226 is connected to the first clip piece 221 and the protrusion. The side of first jaw 22 facing second jaw 24 adjacent the distal end is provided with first clamping teeth 227, specifically, first clamping teeth 227 are located in the middle of the distal end of the side of first jaw 221 facing second jaw 24, and first clamping teeth 227 include a plurality of splines each extending in an axial direction substantially parallel to axial bore 224. The distal end of the first clamping head 22 is provided with a spring catch 228, and in this embodiment, the side of the first clamping piece 221 facing the second clamping head 24 is provided with inclined spring catches 228 on two opposite sides of the first clamping teeth 227.

As shown in fig. 10 and 11, the second clamping head 24 includes a second clamping piece 241, a second clamping tooth 243 is disposed adjacent to the distal end of the side surface of the second clamping head 24 facing the first clamping head 22, specifically, the second clamping tooth 243 is disposed adjacent to the distal end of the side surface of the second clamping piece 241 facing the first clamping head 22, the second clamping tooth 243 includes a plurality of tooth slots, and each tooth slot of the second clamping tooth 243 extends in the same direction as the tooth slot of the first clamping tooth 227. When the first chuck 22 and the second chuck 24 are rotatably connected by the rotating shaft 27, the first teeth 227 of the first chuck 22 and the second teeth 243 of the second chuck 24 are dislocated and can be engaged with each other, so that the first chuck 22 rotates towards the second chuck 24, and the first teeth 227 and the second teeth 243 extrude the locking pin 300 placed in the gap 25 into a shape with curvature. The proximal end of the second collet 24 defines a shaft hole 244 along an axial direction parallel to the shaft hole 224, and the shaft 27 is received in the shaft hole 244. Specifically, the axial bore 244 is located adjacent the proximal end of the side of the second jaw 241 facing the first jaw 22. The proximal end of the second jaw 241 facing the side of the first collet 22 defines a receiving slot 246, the proximal end of the receiving slot 246 extends through the proximal end of the second jaw 241, and the receiving slot 246 is configured to receive the coupling hook 223 of the first collet 22. One side of the second clamping piece 241 facing away from the second clamping teeth 243 is provided with a positioning portion 247, and the positioning portion 247 is used for fixing the chuck assembly 20 in the pushing assembly 60.

As shown in fig. 7, the collet assembly 20 further includes an elastic member 28, the elastic member 28 is used for rotational restoration of the first collet 22 and/or the second collet 24 so that the locking pin 300 is inserted into the gap 25 between the first collet 22 and the second collet 24, and after the first collet 22 and the second collet 24 compress the locking pin 300, the first collet 22 is restored so that the locking pin 300 is smoothly released.

In this embodiment, the elastic element 28 is located between the first chuck 22 and the second chuck 24, and the elastic element 28 is a spring plate, which includes a fixing portion 282 located on the second chuck 24 and an elastic portion 284 extending from the fixing portion 282 to the first chuck 22 in an inclined manner. Specifically, the fixing portion 282 is a rectangular piece, two opposite ends of one side of the rectangular piece away from the rotating shaft 27 are respectively provided with an elastic portion 284, and each elastic portion 284 is an arc-shaped piece extending from the rectangular piece toward the first chuck 22 in an inclined manner. One end of the elastic part 284 away from the fixing part 282 is bent toward the second clip head 24, and one end of the elastic part 284 away from the fixing part 282 is provided with an abutting surface 285 contacting the first clip head 22, specifically, the abutting surface 285 slidably abuts against the corresponding clip groove 228. Preferably, the abutment surface 285 is an arcuate surface.

As shown in fig. 7 and 12, when assembling the cartridge assembly 20, the fixing portion 282 of the elastic member 28 is fixed to the second clip 241 of the second cartridge 24, the coupling hook 223 of the first cartridge 22 is inserted into the receiving groove 246 of the second cartridge 24, the shaft hole 224 of the first cartridge 22 is aligned with the shaft hole 244 of the second cartridge 24, the shaft 27 is inserted into the shaft holes 224 and 244, and the through hole 271 of the shaft 27 faces the wire passing hole 225 of the first cartridge 22. At this time, the elastic element 28 is located between the first chuck 22 and the second chuck 24, the abutting surface 285 of the elastic element 28 contacts the spring clip groove 228 of the first chuck 22, and the through hole 271 communicates with the gap between the first chuck 22 and the second chuck 24; first teeth 227 and second teeth 243 are offset from each other such that the distal surfaces of first jaw 22 and second jaw 24 are not coplanar.

Referring to fig. 13 and 14, when a force is applied to the first chuck 22 to rotate the first chuck 22 along the rotating shaft 27 toward the second chuck 24, that is, the distal end of the first chuck 22 approaches the distal end of the second chuck 24, the elastic element 28 is pressed by the first chuck 24 to be elastically deformed, the contact surface 285 of the elastic element 28 is slidably contacted with the spring slot 228 of the first chuck 22, and the first clamping teeth 227 move toward the second clamping teeth 243 until the first clamping teeth 227 and the second clamping teeth 243 are engaged with each other. During the rotation of the first clamping teeth 227 relative to the second clamping teeth 243, the through hole 271 of the rotating shaft 27 and the wire passing hole 225 of the first clamping head 22 are always in a communication state.

In other embodiments, the second chuck 24 is provided with a coupling hook, the first chuck 22 is provided with a receiving groove corresponding to the coupling hook, and the first chuck 22 and the second chuck 24 are rotatably connected through a rotating shaft.

In other embodiments, the fixing portion 282 of the elastic element 28 may be positioned at the first chuck 22, the elastic portion 284 of the elastic element 28 extends obliquely toward the second chuck 24, and the contact surface 285 of the elastic portion 284 is in contact with the second chuck 24 in a sliding manner.

In other embodiments, the elastic element 28 may also be a spring or an elastic block disposed between the first chuck 22 and the pushing assembly 60, and the spring or the elastic block is used for resetting the first chuck 22.

Referring to fig. 15 and 16, the driving assembly 40 includes a rod member 42, a driving member 44 rotatably connected to a proximal end of the rod member 42, and a link pin 45 connected between the rod member 42 and the driving member 44, the threading passage 26 passes through the rod member 42 and the driving member 44, the proximal end of the driving member 44 is rotatably connected to the pushing assembly 60, and the driving member 44 rotates relative to the pushing assembly 60 and moves axially to drive the rod member 42 to slidably push the first chuck 22 axially, so that the first chuck 22 rotates relative to the second chuck 24 with the rotating shaft 27 as a rotation center. In this embodiment, the driving member 44 includes a screw 442 and a rotating mandrel 445 axially connected to the screw 442, specifically, a distal end of the rotating mandrel 445 is fixedly connected to the screw 442, a proximal end of the rotating mandrel 445 is fixedly connected to the movable portion 84, and the rotation of the movable portion 84 can drive the rotating mandrel 445 and the screw 442 to rotate together.

As shown in fig. 17 and 18, the push rod member 42 includes a push rod 421 for axially slidably abutting against the guide surface 226 of the first chuck 22, and a connection block 423 disposed at a proximal end of the push rod 421, and the push rod 421 is located at one side of the connection block 423 in the radial direction. The connecting block 423 is provided with a through hole 424 along the axial direction, and the through hole 424 penetrates through the distal end face and the proximal end face of the connecting block 423. One end of the push rod 421 away from the connecting block 423 is provided with an arc-shaped sliding-assistant surface 426, and the sliding-assistant surface 426 is used for slidably abutting against the sliding-guiding surface 226. Specifically, one end of the top bar 421 away from the connecting block 423 is convexly provided with an abutting block 425, and the sliding guide surface 226 is arranged on the outer side surface of the abutting block 425. In this embodiment, the connection block 423 is a cylindrical block, the through hole 424 extends along an axial line of the cylindrical block, and an outer side surface of the push rod 421 is coplanar with an outer side surface of the connection block 423.

In other embodiments, the abutting block 425 of the push rod 421 can be omitted, and the sliding guide surface 226 is directly disposed on the distal end surface of the push rod 421.

As shown in fig. 19, the proximal end of the screw 442 is provided with a fixing hole 4420 along the axial center line thereof for fixing the rotating shaft 445. The distal end of screw 442 is pivotally connected to the proximal end of ram member 42 by link pin 45.

Specifically, the distal end of the screw 442 is provided with a connecting hole 4422 along the axial line thereof, the connecting hole 4422 is communicated with the fixing hole 4420, the aperture of the connecting hole 4422 is smaller than that of the fixing hole 4420, and a step surface 4425 is formed between the connecting hole 4422 of the screw 442 and the fixing hole 4420. The rotating mandrel 445 is a hollow shaft rod, that is, the rotating mandrel 445 is provided with a hollow inner hole 4450 in the axial direction, the distal end of the rotating mandrel 445 is fixed in the fixing hole 4420, and the hollow inner hole 4450 of the rotating mandrel 445 is communicated with the connecting hole 4422.

As shown in fig. 20, the link pin 45 includes a cylindrical pin body 451 and a stopper ring 453 provided on an outer peripheral surface of one end of the pin body 451, an outer diameter of the pin body 451 is slightly smaller than a bore diameter of the connection hole 4422, and an outer diameter of the stopper ring 453 is larger than the bore diameter of the connection hole 4422 and smaller than the bore diameter of the fixing hole 4420. The connecting rod pin 45 is axially provided with a lead hole 455.

Referring to fig. 15-21, in the assembled driving assembly 40, the rotating shaft 445 is fixedly connected to the screw 442, and the rotation of the rotating shaft 445 can drive the screw 442 to rotate axially; the hollow inner hole 4450 of the rotating spindle 445 and the lead hole 455 of the link pin 45 communicate.

In other embodiments, the proximal end of the pin body 451 of the link pin 45 is fixed to the screw 442, and the distal end of the pin body 451 is rotatably connected to the connection block 423 of the pin member 42, i.e., the distal end of the pin body 451 is rotatably connected to the through hole 424. The distal end of the pin body 451 is provided with a stopper ring 453 stopped at the distal end surface of the connection block 423 to prevent the pin body 451 from being separated from the plunger member 42.

Referring to fig. 22 to 29, the pushing assembly 60 includes a thrust tube 62 rotatably sleeved on the screw 442, a front end outer tube 64 connected to a distal end of the thrust tube 62, a pushing shaft 66 connected to a distal end of the thrust tube 62, and an end cap 67 covering a distal end of the front end outer tube 64. The thrust pipe 62 is provided with an internal thread corresponding to the screw rod 442, and the rotation of the rotary mandrel 445 drives the screw rod 442 to rotate relative to the thrust pipe 62 and move along the axial direction; preferably, the inner wall of the thrust tube 62 is provided with an internal thread 622 corresponding to the screw 442, the distal end of the pushing shaft 66 is fixedly connected to the proximal end of the thrust tube 62, and the proximal end of the pushing shaft 66 is fixedly connected to the fixing portion 82.

As shown in fig. 24, a through hole 623 is axially formed in the thrust tube 62, the internal thread 622 is disposed on the inner circumferential surface of the through hole 623, a clamping ring groove 624 is formed around the through hole 623 at the proximal end of the thrust tube 62, and the distal end of the pushing shaft 66 is fixedly connected to the clamping ring groove 624; the distal end of the thrust tube 62 projects from the periphery of the through hole 623 to a distal end by a snap ring 626, the snap ring 626 is used for fixedly connecting the proximal end of the front end outer tube 64, and the internal thread 622 also passes through the inner circumferential surface of the snap ring 626.

As shown in fig. 25 and 26, the front end outer tube 64 is a hollow tube, i.e., the front end outer tube 64 is axially provided with a through hole 641. A clamping ring groove 644 is formed around the through hole 641 at the near end of the front end outer tube 64, and the clamping ring 626 of the thrust tube 62 is connected to the clamping ring groove 644; the distal end of the front outer tube 64 protrudes distally around the through hole 641 to form a snap ring 646, and the snap ring 646 is used for fixedly connecting the end cap 67. Two opposite shaft holes 647 are formed in the middle of the front end outer tube 64 in the radial direction and used for mounting two opposite ends of the rotating shaft 27.

The pushing shaft 66 is a hollow outer tube, i.e., the pushing shaft 66 is axially provided with a hollow inner cavity 662.

As shown in fig. 27 and 28, the end cap 67 defines a suture entrance 670 corresponding to the void 25, and the locking pin 300 can be inserted into the void 25 through the suture entrance 670. Specifically, the end cap 67 includes a circular cover plate 672 and an annular connecting plate 674 disposed at the periphery of the cover plate 672, the connecting plate 674 is used for sleeving the clamping ring 646 of the front end outer tube 64, and the suture inlet 670 is axially opened at the middle of the cover plate 672. Suture inlet 670 includes a central opening 671 in the middle of cover plate 672 and side slots 673 on opposite sides of central opening 671, each side slot 673 extending radially for receiving compressed staple 300. In this embodiment, the central opening 671 is a circular hole, and the width of each side slot 673 is slightly smaller than the diameter of the central opening 671.

Referring to fig. 30, when the remote suture locking device 100 is assembled, the thrust tube 62 is sleeved outside the screw rod 442, so that the internal thread 622 of the thrust tube 62 is screwed with the external thread of the screw rod 442, and the distal end surface of the screw rod 442 is flush with the distal end surface of the thrust tube 62 or the distal end surface of the screw rod 442 extends out of the distal end surface of the thrust tube 62; inserting the pin body 451 of the link pin 45 into the connection hole 4422 through the fixing hole 4420 of the screw 442 such that the pin body 451 is exposed to the distal end surface of the connection hole 4422 until the stopper ring 453 contacts the step surface 4425; inserting the pin body 451 into the through hole 424 of the connecting block 423 and fixing the pin body by laser welding or the like, wherein the distal end surface of the pin body 451 is flush with the distal end surface of the connecting block 423; the far end of the rotating mandrel 445 is fixedly inserted into the fixing hole 4420 of the screw 442, at this time, the ejector rod piece 42 is rotatably connected to the far end of the screw 442 through the connecting rod pin 45, the stop ring 453 prevents the ejector rod piece 42 from being separated from the screw 442, the rotating mandrel 445 is fixedly connected with the screw 442, the rotation of the rotating mandrel 445 can drive the screw 442 to rotate, and the hollow inner hole 4450 of the rotating mandrel 445 is communicated with the lead hole 455 of the connecting rod pin 45; sleeving the pushing shaft 66 outside the rotating mandrel 445, and inserting the distal end of the pushing shaft 66 into the clamping ring groove 624 of the thrust tube 62; the clamping ring 626 of the thrust tube 62 is inserted and fixed into the clamping ring groove 644 of the front end outer tube 64, so that the far end of the thrust tube 62 is fixedly connected to the near end of the front end outer tube 64; fixing the clamp head assembly 20 at the far end inside the front end outer tube 64, specifically, fixing the positioning part 247 of the second clamp head 24 on the inner circumferential surface of the front end outer tube 64, so that the push rod 421 faces the first clamp head 22, that is, the slide-assisting surface 426 on the push rod 421 corresponds to the slide-guiding surface 226 of the first clamp head 22, and the two opposite ends of the rotating shaft 27 are respectively installed inside two shaft holes 647 of the front end outer tube 64; sleeving the connecting plate 674 of the end cover 67 on the clamping ring 646 of the front end outer tube 64, so that the end cover 67 is fixedly connected to the distal end of the front end outer tube 64, and the suture inlet 670 faces the gap 25 between the first chuck 22 and the first chuck 24, at this time, the hollow inner cavity 662 of the pushing shaft 66, the through hole 623 of the thrust tube 62, the through hole 641 of the front end outer tube 64 and the suture inlet 670 of the end cover 67 are axially communicated; the proximal end of the rotating mandrel 445 and the proximal end of the pushing shaft 66 are connected to the movable portion 84 and the fixed portion 82, respectively. At this time, the gap 25, the through hole 271, the thread passing hole 225, the through hole 641, the lead hole 455 and the hollow inner hole 4450 are axially communicated with each other, and a threading passage 26 for threading the suture thread is formed.

Referring to fig. 31 to fig. 36, the following description will be made of the use of the interventional remote suture locking device 100 according to the present invention, taking a valve repair of a mitral valve of a heart as an example.

The mitral valve is a one-way "valve" between the Left Atrium (LA) and the Left Ventricle (LV), which ensures blood flow from the left atrium to the left ventricle. A normal, healthy mitral valve has a plurality of chordae tendineae, and when the left ventricle is in a diastolic state, the leaflets of the mitral valve are in an open state, and blood flows from the left atrium to the left ventricle; when the left ventricle is in a contraction state, the chordae tendineae are stretched, and the valve leaflets are prevented from being flushed to the atrium side by blood flow. As shown in fig. 31, the leaflets of the mitral valve are divided into an anterior leaflet 401 and a posterior leaflet 403, and if the mitral valve is diseased and the left ventricle is in a contracted state, the anterior leaflet 401 and the posterior leaflet 403 cannot return to a closed state as in a normal state, and the impulse of blood further causes the leaflets to fall into the left atrium, which causes blood regurgitation.

The use of the interventional remote suture knot device 100 in a valve repair procedure with a first embodiment of the invention is as follows:

the first step is as follows: as shown in fig. 31, firstly, after the femoral vein puncture and transseptal puncture of a patient, a plurality of suture lines 500 with elastic gaskets 501 are respectively implanted into the anterior leaflet 401 and the posterior leaflet 403 of the mitral valve, and the point contact between the suture lines 500 and the leaflets is converted into the surface contact between the elastic gaskets 501 and the leaflets, so that the risk of tearing of the leaflets can be effectively reduced;

the second step is that: as shown in fig. 32 and fig. 34, a plurality of sutures 500 on both side leaflets are all threaded into the threading cavity 301 of the locking nail 300 outside the patient body, and the proximal ends of the sutures 500 pass through the threading cavity 301 of the locking nail 300 of the intervention remote suture locking device 100, the gap 25 between the first clamping head 22 and the second clamping head 24, the through hole 271 of the rotating shaft 27, the thread passing hole 225 of the first clamping head 22, the through hole 641 of the front end outer tube 64, the lead hole 455 of the connecting rod pin 45 and the hollow inner hole 4450 of the rotating spindle 445 in sequence and then pass out from the proximal end of the movable part 84;

the third step: as shown in fig. 32 and 35, the distal end of the interventional remote suture locking device 100 is pushed into the heart through the femoral vein and interatrial septum by means of a bending sheath (not shown), moving closer to the leaflets of the mitral valve while pulling the suture 500 until the distal end of the interventional remote suture locking device 100 reaches a predetermined position;

the fourth step: adjusting the tightness of the sutures 500 on the anterior leaflet 401 and the posterior leaflet 403, respectively, while determining by ultrasound the state of minimum mitral regurgitation, when this state is reached, stopping the adjustment, maintaining the tightness of the two sets of sutures 500, i.e. maintaining the relative distance between the anterior leaflet 401 and the posterior leaflet 403 of the mitral valve;

the fifth step: keeping the fixed part 82 of the handle 80 still, driving the movable part 84 to rotate towards the far end, at this time, the rotating mandrel 445 drives the screw rod 442 to move towards the far end relative to the pushing shaft 66, the screw rod 442 drives the ejector rod 42 to move towards the far end, the far end of the ejector rod 421 of the ejector rod 42 continuously extrudes the first chuck 22, so that the first chuck 22 approaches towards the second chuck 24, the locking nail 300 between the first chuck 22 and the second chuck 24 is pressed, the elastic part 28 is extruded and elastically deformed until the locking nail 300 deforms, the suture 500 in the locking nail 300 is locked together, then the movable part 84 is driven to move towards the near end, the ejector rod 421 releases the extrusion on the first chuck 22, the first chuck 22 expands and restores to the initial position under the elastic resetting effect of the elastic part 28, and the deformed locking nail 300 is released from the suture inlet 670 of the end cover 67;

and a sixth step: as shown in fig. 33 and 36, the distal end of the interventional remote suture locking device 100 is withdrawn from the patient, the locking nail 300 is left in the patient, the suture 500 at the end of the locking nail 300 is cut off, and at this time, the locking nail 300 fixes the two sets of sutures 500 passing through the anterior leaflet 401 and the posterior leaflet 403, respectively, of the mitral valve together, and the anterior leaflet 401 and the posterior leaflet 403 of the mitral valve complete the edge-to-edge repair to form a double-meshed structure.

It will be appreciated that while the use of the present invention has been described with respect to an interventional remote suture locking device for use in interventional mitral valve repair procedures via the femoral vein-interatrial septum-left atrium-mitral valve approach, the present invention may also be used for locking and securing sutures in other surgical procedures.

The interventional remote suture knot device 100 of the present invention is particularly useful in the following scenarios, such as:

(1) performing an interventional mitral valve repair procedure via a femoral vein-interatrial septum-left atrium-mitral valve pathway;

(2) performing an interventional mitral valve repair procedure via a femoral artery-aortic arch-aortic valve-left ventricle-mitral valve pathway;

(3) interventional mitral valve repair procedures are performed via the jugular vein-interatrial septum-left atrium-mitral valve approach.

The following scenario applies as well: (1) performing an interventional tricuspid valve repair procedure via the femoral vein-right atrium-tricuspid valve pathway; (2) interventional tricuspid valve repair surgery is performed via the jugular vein-right atrium-tricuspid valve approach. Remotely operating the interventional remote suture locking device 100 outside the patient's body secures the suture 500 implanted on the leaflets with the locking staples 300 by way of minimally invasive intervention.

In other embodiments, the rod member 42 is connected to the front end outer tube 64 by axially extending guide slots and guide bars, so as to ensure that the rod member 42 moves only axially and does not rotate within the through hole 641 of the front end outer tube 64. Specifically, the outer wall of the ejector rod 42 is provided with a guide bar extending in the axial direction, and the inner circumferential surface of the front end outer tube 64 is provided with a guide groove corresponding to the guide bar; or the outer wall of the ejector rod 42 is provided with a guide groove extending along the axial direction, and the inner circumferential surface of the front end outer tube 64 is provided with a guide bar corresponding to the guide groove, and the guide bar can slide along the axial direction in the guide groove.

Referring to fig. 37 to 40, the structure of the intervention type remote suture locking device provided by the second embodiment of the present invention is similar to that of the first embodiment, except that: the threading channel 26a of the second embodiment is slightly different from the first embodiment in that a gap 229 for threading is provided between the proximal end of the first jaw 22a and the proximal end of the second jaw 24. That is, a gap 25 between the distal end of first jaw 22a and the distal end of second jaw 24, a gap 229 between the proximal end of first jaw 22a and the proximal end of second jaw 24, a through hole 641 of front end outer tube 64, a lead hole 455 of link pin 45, and a hollow inner hole 4450 of rotary shaft 445 form threading channel 26a, and suture 500 is passed through and received in threading channel 26 a.

Referring to fig. 38, the first chuck 22a of the second embodiment is similar to the first embodiment except that: the first cartridge 22a of the second embodiment is formed by omitting the wire passing hole 225 from the first cartridge 22 of the first embodiment, and providing a gap 229 between the coupling hook 223 of the first cartridge 22a of the assembled cartridge assembly and the proximal end of the second cartridge 24.

Referring to fig. 39, the rotating shaft 27a of the second embodiment is similar to the first embodiment, except that: the rotating shaft 27a of the second embodiment is formed by omitting the through-hole 271 from the rotating shaft 27 of the first embodiment.

As shown in fig. 40 and 41, the use of the interventional remote suture locking device of the second embodiment is similar to the first embodiment, except that: in a second step, the proximal end of suture 500 is threaded out of the proximal end of movable portion 84 through the distal opening of staple 300 and threading lumen 301 of the interventional remote suture locking device, gap 25 between first jaw 22a and second jaw 24, gap 229 between the proximal end of first jaw 22a and the proximal end of second jaw 24, through hole 641 of front end outer tube 64, lead hole 455 of connecting rod pin 45, and hollow inner hole 4450 of rotating mandrel 445.

In the second embodiment of the present invention, the first chuck 22a does not need to process the wire passing hole 225, and the rotating shaft 27a does not need to process the through hole 271, so that the assembly difficulty of the rotating shaft 27a is reduced, the production efficiency is improved, and the production cost and the processing cost are saved.

Referring to fig. 42 to 47, the structure of the intervention type remote suture locking device provided by the third embodiment of the present invention is similar to that of the first embodiment, except that the structure of the screw 442a, the thrust tube 62a and the top rod 42a in the third embodiment is different from that of the first embodiment, as follows:

the driving member 44 of the interventional remote suture locking device in the third embodiment comprises a screw 442a and a rotating mandrel 445 axially connected to the proximal end of the screw 442a, the ejector rod 42a is provided with a through hole along the axial line of the screw 442a, the inner surface of the through hole is provided with an internal thread 428 corresponding to the screw 442a, the screw 442a is driven to rotate by the rotating mandrel 445, and the ejector rod 42a is driven to move axially by the rotating mandrel 442 a.

As shown in fig. 43 and 44, the screw 442a is a hollow screw rod, that is, the screw 442a is provided with a threading hole 4426 along the axial line thereof, and the threading hole 4426 is used for threading a suture. The outer wall of the proximal end of the screw shaft 442a is provided with a rotating ring 4427 in a radial direction, the proximal end face of the screw shaft 442a is provided with a fixed cylinder 4428 protruding from the circumference of the threading hole 4426 in the axial direction of the screw shaft 442a toward the proximal end, and the outer diameter of the fixed cylinder 4428 is larger than the outer diameter of the screw shaft 442a and smaller than the outer diameter of the rotating ring 4427. The fixed cylinder 4428 is axially provided with a fixed hole 4429 communicated with the threading hole 4426, and the inner diameter of the fixed hole 4429 is larger than that of the threading hole 4426.

As shown in fig. 45, the top rod member 42a of the third embodiment is added with at least one guiding and sliding plate 427 and an internal thread 428 corresponding to the external thread of the screw rod 442a on the inner circumferential surface of the through hole 424 in addition to the first embodiment. Specifically, at least one guide sliding plate 427 is disposed at the distal end of the connecting block 423 and extends along the length direction of the push rod 421, the inner surface of the front end outer tube 64 is provided with a guide sliding groove 648 (as shown in fig. 42) corresponding to the guide sliding plate 427, and the guide sliding plate 427 is slidably inserted into the guide sliding groove 648, so as to prevent the push rod 42a from rotating in the front end outer tube 64.

As shown in fig. 42, the thrust tube 62a of the third embodiment omits the internal thread 622 from the thrust tube 62 of the first embodiment, and the fixed cylinder 4428 of the screw 442a is rotatably accommodated in the through hole 623 of the thrust tube 62. A retaining ring 649 is provided radially protruding from the inner circumferential surface of the through hole 641 of the front end outer tube 64 near the proximal end.

When assembling the interventional remote suture locking device of the third embodiment, the distal end of screw 442a is inserted into through hole 641 from the proximal end of forward outer tube 64 until rotating ring 4427 of screw 442a stops at setting ring 649; inserting the connecting block 423 of the ejector pin member 42a into the through hole 641 from the distal end of the front end outer tube 64, screwing the external thread of the screw 442a to the internal thread 428 of the connecting block 423 until the proximal end face of the ejector pin member 42a contacts the retaining ring 649, and the sliding guide plate 427 is slidably inserted into the sliding guide groove 648; the collet assembly is then secured at the distal end within the forward outer tube 64 in accordance with the assembly process of the first embodiment; sleeving the connecting plate 674 of the end cover 67 on the clamping ring 646 of the front end outer tube 64; fixedly connecting the far end of the thrust tube 62a to the near end of the front end outer tube 64, so that the far end surface of the thrust tube 62a contacts the rotating ring 4427, the fixed cylinder 4428 is rotatably accommodated in the through hole 623, and the far end surface of the thrust tube 62a and the positioning ring 649 together limit the rotating ring 4427 to move axially; the far end of the rotating mandrel 445 is fixedly inserted into the fixed cylinder 4428; sleeving the pushing shaft 66 outside the rotating mandrel 445, wherein the distal end of the pushing shaft 66 is fixed at the proximal end of the thrust tube 62; the proximal ends of the thrust tube 62 and the pushing shaft 66 are fixedly connected to the movable portion 84 and the fixed portion 82, respectively. At this time, the gap 25, the through hole 271, the threading hole 225, the through hole 641, the threading hole 4426 and the hollow inner hole 4450 are axially communicated with each other, and a threading channel 26 is formed to facilitate the threading of the suture thread through the threading channel 26; the rotation of the movable portion 84 can drive the screw rod 442a to rotate, and since the top rod 42a is screwed to the screw rod 442a and the sliding guide plate 427 and the sliding guide groove 648 limit the rotation of the top rod 42a, the rotation of the screw rod 442a drives the top rod 42a to move axially, so that the top rod 421 slidably presses against the first chuck 22.

Referring to fig. 46 and 47, the use of the interventional remote suture locking device of the third embodiment is similar to the first embodiment, except that: in a second step, the proximal end of suture 500 is passed out of the gap 25 between first jaw 22 and second jaw 24 and through bore 271 of shaft 27.

In the fifth step, the fixed part 82 of the handle 80 is kept still, the movable part 84 is driven to rotate, at this time, the rotating mandrel 445 drives the screw rod 442a to rotate relative to the front end outer tube 64, the rotation of the screw rod 442a drives the ejector pin 42a to move towards the far end, the first clamping head 22 is continuously extruded until the locking nail 300 is deformed, and the suture threads 500 in the locking nail 300 are locked together; then, the movable portion 84 is driven to rotate to drive the rotating shaft 445 and the screw 442a, the first clamping head 22 is opened and restored to the original position by the elastic restoration of the elastic member 28, and the deformed locking nail 300 is released from the suture inlet 670 of the end cap 67.

The foregoing is illustrative of embodiments of the present invention, and it should be noted that modifications and adaptations to those skilled in the art may be made without departing from the principles of the embodiments of the present invention and are intended to be within the scope of the present invention.

Claims

1. The utility model provides a long-range stylolite of intervention formula locking device, its characterized in that, long-range stylolite of intervention formula locking device includes the cartridge assembly, the distal end of cartridge assembly is equipped with the space that is used for placing the lock nail, the lock nail is equipped with the threading chamber along the axial, the threading passageway is seted up along its axial to the cartridge assembly, the stylolite is worn to locate the threading chamber of lock nail reaches the threading passageway, the cartridge assembly extrusion the lock nail makes the lock nail warp in order to fix the stylolite.

2. The interventional remote suture knot device of claim 1, wherein the jaw assembly comprises a first jaw and a second jaw connected or integrally formed to each other, the connection of the first and second jaws being in communication with the threading channel.

3. The interventional remote suture locking device of claim 2, wherein the proximal end of the first collet is rotatably coupled to the proximal end of the second collet by a shaft, the shaft defining a through-hole communicating with the threading channel.

4. The interventional remote suture knot device of claim 3, wherein the collet assembly further comprises a resilient member for rotational return of the first collet and/or the second collet.

5. The interventional remote suture knot device of claim 4, wherein the resilient member comprises a fixed portion positioned at the second jaw and a resilient portion extending obliquely from the fixed portion to the first jaw, an end of the resilient portion distal from the fixed portion being provided with an abutment surface contacting the first jaw.

6. The interventional remote suture knot device of claim 5, wherein the abutment surface is an arcuate surface, wherein a distal end of the first collet is provided with a spring catch, and wherein the abutment surface slidably abuts against the spring catch.

7. The interventional remote suture locking device of claim 2, wherein a side of the first jaw facing the second jaw is provided adjacent the distal end with first gripping teeth, a side of the second jaw facing the first jaw is provided adjacent the distal end with second gripping teeth, the first gripping teeth and the second gripping teeth are misaligned and intermeshable, the first and second gripping teeth extruding the staple into a shape having a curvature.

8. The interventional remote suture locking device of claim 2, wherein the proximal end of the first collet and/or the proximal end of the second collet is axially provided with a wire passing hole, the wire passing hole communicating with the threading channel.

9. The interventional remote suture keying device of claim 2, further comprising a drive assembly disposed proximal to the cartridge assembly, the threading channel extending through the drive assembly.

10. The interventional remote suture locking device of claim 9, further comprising a pushing assembly sleeved outside the collet assembly and the driving assembly, wherein the driving assembly comprises a pushing rod and a driving member rotatably connected to a proximal end of the pushing rod, the proximal end of the driving member is connected to the pushing assembly, and the driving member moves distally relative to the pushing assembly to drive the pushing rod to slidably push the collet assembly axially to squeeze the locking pin.

11. The interventional remote suture knot device of claim 10, wherein a side of the first jaw facing away from the second jaw is provided with an inclined slide guide surface, and the ejector pin member comprises an ejector pin for axially slidably abutting against the slide guide surface.

12. The interventional remote suture locking device of claim 11, wherein an end of the push rod proximate the slide guide surface is provided with an arcuate slide assist surface that slidingly abuts the slide guide surface.

13. The interventional remote suture knot device of claim 10, wherein the driving member comprises a screw rod and a rotating mandrel axially connected to a proximal end of the screw rod, a distal end of the screw rod is connected to the ejector rod member, the pushing assembly comprises a thrust tube sleeved on the screw rod and a front outer tube connected to a distal end of the thrust tube, the collet assembly is located at a distal end of the front outer tube, the ejector rod member is located at a proximal end of the front outer tube, and the rotating mandrel drives the screw rod to move axially to push the ejector rod member to slide axially.

14. The interventional remote suture locking device of claim 13, wherein the thrust tube is provided with internal threads corresponding to the threaded rod, and rotation of the rotating mandrel causes the threaded rod to rotate and move axially relative to the thrust tube.

15. The interventional remote suture tying device of claim 13 wherein a proximal end of the screw has a fixing hole along an axial center line thereof for fixing the rotating mandrel, and a distal end of the screw is rotatably connected to a proximal end of the ejector pin by a connecting rod pin.

16. The interventional remote suture locking device of claim 15, wherein a distal end of the screw rod is provided with a connecting hole along an axial line thereof, the ejector pin member is provided with a through hole along an axial line direction of the screw rod, a distal end of the connecting rod pin is fixed to the through hole, a proximal end of the connecting rod pin is rotatably inserted into the connecting hole, the rotating mandrel is provided with a hollow inner hole axially, the connecting rod pin is provided with a lead hole axially, and the threading channel communicates the hollow inner hole of the rotating mandrel and the lead hole of the connecting rod pin.

17. The interventional remote suture knot device of claim 16, wherein the connecting hole is communicated with the fixing hole, the diameter of the connecting hole is smaller than that of the fixing hole, a step surface is formed between the connecting hole and the fixing hole of the screw, and the proximal end of the connecting rod pin is provided with a stop ring which is rotatably contacted with the step surface.

18. The interventional remote suture knot device of claim 13, wherein the pushing assembly further comprises an end cap covering the distal end of the front end outer tube, the end cap defining a suture entry opening corresponding to the void through which the locking pin is inserted into the void.

19. The interventional remote suture knot device of claim 18, wherein the suture inlet comprises a central opening in a central portion and side slots on opposite sides of the central opening for receiving the crushed staples.

20. The interventional remote suture locking device of claim 13, wherein the ejector pin is provided with a through hole along an axial line of the screw, an inner surface of the through hole is provided with an inner thread corresponding to the screw, and the rotation of the rotating mandrel drives the screw to rotate and move axially.

21. The interventional remote suture locking device of claim 20, wherein the inner lumen of the outer forward tube is provided with a positioning ring, the screw is provided with a rotating ring that rotatably abuts the positioning ring, and the distal end face of the thrust tube cooperates with the positioning ring to limit axial movement of the rotating ring.

22. The interventional remote suture knot device of claim 21, wherein the ejector pin member and the leading end outer tube are slidably connected therebetween by an axially extending guide slide and guide slot.