CN112180023A - Liquid chromatography analysis method and device and liquid chromatography workstation - Google Patents
Liquid chromatography analysis method and device and liquid chromatography workstation Download PDFInfo
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- G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
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Abstract
The invention provides a liquid chromatography analysis method, a device and a liquid chromatography workstation, comprising: receiving a search instruction of a user; wherein the search instruction comprises keywords; searching alternative method files matched with the keywords from a preset built-in method library so that a user can select a target method file from the alternative method files; wherein, the alternative method files are one or more; the built-in method library comprises a plurality of method files with preset operation parameters of the liquid chromatograph; and sending the target method file selected by the user to the liquid chromatograph so that the liquid chromatograph detects the tested substance according to the operating parameters in the target method file. The invention can lead the detection personnel to quickly acquire the detection method, save time and improve the detection working efficiency and accuracy.
Description
Technical Field
The invention relates to the technical field of liquid chromatography, in particular to a liquid chromatography method, a liquid chromatography device and a liquid chromatography workstation.
Background
The liquid chromatogram workstation is an important component of the liquid chromatograph, and the operating parameters of the liquid chromatograph can be set through the liquid chromatogram workstation matched with the liquid chromatograph so as to control the work of each module of the liquid chromatograph; and then collecting chromatographic data output by the liquid chromatograph, and carrying out corresponding data processing and analysis to obtain qualitative and quantitative analysis of the test substance. However, since different substances are analyzed by different methods and different parameters need to be set, for example, the chinese pharmacopoeia has detailed method regulations for the conventional common herbs, decoction pieces, chemicals, biological products, etc., so that the testing personnel needs to set the relevant operating parameters in the liquid chromatography workstation by referring to the pharmacopoeia manual before testing, and the process is complicated and is prone to error.
Disclosure of Invention
In view of this, the present invention provides a liquid chromatography method, a liquid chromatography device and a liquid chromatography workstation, which enable a detection person to quickly obtain a detection method, save time, and improve detection efficiency and accuracy.
In a first aspect, an embodiment of the present invention provides a liquid chromatography method, including: receiving a search instruction of a user; wherein the search instruction comprises keywords; searching alternative method files matched with the keywords from a preset built-in method library so that a user can select a target method file from the alternative method files; wherein, the alternative method files are one or more; the built-in method library comprises a plurality of method files with preset operation parameters of the liquid chromatograph; and sending the target method file selected by the user to the liquid chromatograph so that the liquid chromatograph detects the tested substance according to the operating parameters in the target method file.
In one embodiment, the method further comprises: and receiving chromatographic data sent by the liquid chromatograph, and analyzing the chromatographic data to obtain a detection result of the tested substance.
In one embodiment, the method further comprises: and providing an editing channel for a user so that the user can edit the operation parameters in the method file through the editing channel.
In one embodiment, the step of sending the target method file selected by the user to the liquid chromatograph includes: and if the preset sending key is triggered, sending the target method file selected by the user to the liquid chromatograph.
In one embodiment, before the step of receiving the search instruction of the user, the method further includes: and if the preset opening key is triggered, providing a search interface for the user so that the user can input a search instruction.
In one embodiment, the method file includes at least one or more of the following elements: the device comprises a summary unit, an infusion pump unit, an automatic sample injector unit, a column temperature box unit and a detector unit.
In one embodiment, the liquid chromatograph operating parameters include at least one or more of the following: acquisition time, column temperature, mobile phase flow, gradient elution parameters, detector sampling rate, maximum absorption wavelength, and autosampler parameters.
In a second aspect, an embodiment of the present invention provides a liquid chromatography apparatus, including: the instruction receiving module is used for receiving a search instruction of a user; wherein the search instruction comprises keywords; the searching module is used for searching the alternative method files matched with the keywords from a preset built-in method library so that a user can select the target method files from the alternative method files; wherein, the alternative method files are one or more; the built-in method library comprises a plurality of method files with preset operation parameters of the liquid chromatograph; and the sending module is used for sending the target method file selected by the user to the liquid chromatograph so that the liquid chromatograph detects the tested substance according to the operating parameters in the target method file.
In a third aspect, embodiments of the present invention provide a liquid chromatography workstation, including a processor and a memory, where the memory stores computer executable instructions capable of being executed by the processor, and the processor executes the computer executable instructions to implement the steps of any one of the methods provided in the first aspect.
In a fourth aspect, the present invention provides a computer-readable storage medium, on which a computer program is stored, where the computer program is executed by a processor to perform the steps of any one of the methods provided in the first aspect.
The embodiment of the invention has the following beneficial effects:
according to the liquid chromatography analysis method, the liquid chromatography analysis device and the liquid chromatography workstation provided by the embodiment of the invention, when a search instruction (the search instruction comprises a keyword) of a user is received, one or more alternative method files matched with the keyword can be searched from a preset built-in method library (comprising a plurality of method files with preset liquid chromatography operating parameters) so that the user can select a target method file from the alternative method files, and then the target method file selected by the user is sent to the liquid chromatography so that the liquid chromatography detects a tested substance according to the operating parameters in the target method file. According to the method, the plurality of method files are stored in the built-in method library in advance, the operation parameters of the liquid chromatograph are set in advance in each method file, when the tested substance is detected, the target method files can be directly searched in the built-in method library and sent to the liquid chromatograph, the operation parameters are not required to be set one by one, and therefore the process of setting the substance detection method is simplified, the detection time is saved, and the detection working efficiency and accuracy are improved.
Additional features and advantages of the invention will be set forth in the description which follows, and in part will be obvious from the description, or may be learned by practice of the invention. The objectives and other advantages of the invention will be realized and attained by the structure particularly pointed out in the written description and claims hereof as well as the appended drawings.
In order to make the aforementioned and other objects, features and advantages of the present invention comprehensible, preferred embodiments accompanied with figures are described in detail below.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, and it is obvious that the drawings in the following description are some embodiments of the present invention, and other drawings can be obtained by those skilled in the art without creative efforts.
FIG. 1 is a flow chart of a liquid chromatography method according to an embodiment of the present invention;
FIG. 2 is a schematic diagram of a search interface provided in an embodiment of the present invention;
FIG. 3 is a diagram illustrating a search results interface according to an embodiment of the present invention;
FIG. 4 is a diagram of a summarization unit according to an embodiment of the present invention;
fig. 5 is a schematic diagram of an infusion pump unit according to an embodiment of the present invention;
FIG. 6 is a schematic diagram of an auto sampler unit according to an embodiment of the present invention;
FIG. 7 is a schematic diagram of a column oven unit according to an embodiment of the present invention;
FIG. 8 is a schematic diagram of an UV-visible light detection unit provided by an embodiment of the present invention;
fig. 9 is a schematic diagram of an operation method of a built-in method library according to an embodiment of the present invention;
FIG. 10 is a schematic structural diagram of a liquid chromatography apparatus according to an embodiment of the present invention;
fig. 11 is a schematic structural diagram of a liquid chromatography workstation according to an embodiment of the present invention.
Detailed Description
To make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions of the present invention will be clearly and completely described below with reference to the accompanying drawings, and it is apparent that the described embodiments are some, but not all embodiments of the present invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
At present, a liquid chromatograph sets a liquid chromatograph method through a matched liquid chromatograph workstation, and because different substances have different analysis methods and various parameters required to be set are different, for example, detailed method regulations are provided for existing common medicinal materials, decoction pieces, chemicals, biological products and the like in Chinese pharmacopoeia, and the chromatograph method is not fixed because research works in new substances, new fields and the like need to grope the chromatograph method, and the pharmacopoeia and other industry standard methods cover most existing analysis methods for common medicinal materials, decoction pieces, chemicals, other substances and the like. Therefore, when analyzing a sample, a detection person needs to set relevant parameters in a liquid chromatography workstation one by one, such as the acquisition time, the parameters of an infusion pump, the parameters of an automatic sample injector, the parameters of an ultraviolet-visible light detector and the like, on one hand, the detection person needs to browse a pharmacopoeia manual for parameter confirmation, and the process is complicated; on the other hand, some substances need a gradient elution program, the process of inputting the gradient program is complicated and is easy to make mistakes, and the phenomenon of abnormal experimental results caused by wrong method setting is more frequent in the use of the liquid chromatograph.
Based on this, the liquid chromatography analysis method, the liquid chromatography analysis device and the liquid chromatography workstation provided by the embodiment of the invention can enable detection personnel to quickly acquire the detection method, save time and improve the detection work efficiency and accuracy.
To facilitate understanding of the present embodiment, a detailed description will be first given of a liquid chromatography method disclosed in the present embodiment, referring to a flowchart of the liquid chromatography method shown in fig. 1, which may be executed by a liquid chromatography workstation, and mainly includes the following steps S102 to S106:
step S102: and receiving a search instruction of a user.
Wherein, the search instruction comprises keywords. In a specific implementation manner, if it is detected that a preset open key is triggered, a search interface is provided for a user to input a search instruction for the user, and the specific user can click the open key to open the search interface. The user inputs the keyword of the detection method to be selected on the search interface, namely sending a search instruction, wherein the keyword can be the name of the tested substance. For convenience of understanding, an embodiment of the present invention provides a schematic diagram of a search interface, referring to the search interface shown in fig. 2, the upper right corner of the search interface includes a search method file column and a search key, a user may input a keyword in the search method file column, and then click the search key or enter is to send a search instruction; the search interface can also display preset built-in method library folders, default method files, Demo folders and the like, and a user can also click the built-in method library folders to search a desired method file in the files.
Step S104: and searching for alternative method files matched with the keywords from a preset built-in method library so that a user can select a target method file from the alternative method files.
Wherein, the alternative method files are one or more; the built-in method library comprises a plurality of method files with preset operation parameters of the liquid chromatograph. In a specific embodiment, the built-in method library comprises a plurality of method files, each method file is preset with corresponding liquid chromatograph operation parameters, each method file corresponds to a test method of a tested substance, and the method files can be named by the name of the tested substance (such as agilawood, mulberry leaves and the like) and test contents (such as content measurement, characteristic map and the like), such as: agilawood-content measurement, agilawood-feature map and the like, therefore, in this embodiment, a user can search for a matched alternative method file in the built-in method library according to an input keyword. Because the content of each tested substance is different, the adopted method is different, the content of different tested substances is the same, the adopted method is different, the same tested substance or the same test content can comprise a plurality of method files, therefore, only one or a plurality of alternative method files searched according to the keywords can be found, and a user can select a required method file (namely a target method file) from the alternative method files according to the self requirement.
Referring to a schematic diagram of a search result interface shown in fig. 3, it is illustrated that after a user inputs "agilawood" click search in a method file search field, two method files, namely, an agilawood-content determination method file and an agilawood-feature map method file, can be found in an internal method. The user can select a desired method file from the two files, take it as a target method file by clicking the method file, and open the target method file by clicking the "ok" button.
Step S106: and sending the target method file selected by the user to the liquid chromatograph so that the liquid chromatograph detects the tested substance according to the operating parameters in the target method file.
In a specific embodiment, when the target method file is sent, if it is detected that a preset sending key is triggered (i.e. a user clicks the sending key of the method interface), the target method file selected by the user is sent to the liquid chromatograph. After receiving the target method file, the liquid chromatograph can control each module to automatically detect the tested substance according to the operating parameters in the method file.
According to the liquid chromatography analysis method provided by the embodiment of the invention, when a search instruction (the search instruction comprises a keyword) of a user is received, one or more alternative method files matched with the keyword can be searched from a preset built-in method library (comprising a plurality of method files with preset liquid chromatograph operation parameters) so that the user can select a target method file from the alternative method files, and then the target method file selected by the user is sent to the liquid chromatograph so that the liquid chromatograph can detect a tested substance according to the operation parameters in the target method file. According to the method, the plurality of method files are stored in the built-in method library in advance, the operation parameters of the liquid chromatograph are set in advance in each method file, when the tested substance is detected, the target method files can be directly searched in the built-in method library and sent to the liquid chromatograph, the operation parameters are not required to be set one by one, and therefore the process of setting the substance detection method is simplified, the detection time is saved, and the detection working efficiency and accuracy are improved.
Further, the method provided by the embodiment of the present invention further includes: and receiving chromatographic data sent by the liquid chromatograph, and analyzing the chromatographic data to obtain a detection result of the tested substance. In a specific embodiment, the liquid chromatograph generates chromatographic data after running the detection method corresponding to the target method file, the liquid chromatograph can send the chromatographic data to the liquid chromatography workstation, and the liquid chromatography workstation can analyze the data according to a built-in analysis method after receiving the chromatographic data, so as to obtain a detection result, such as a characteristic map, of the substance to be tested.
In view of that the detection method of each substance may change according to the actual situation, or the analysis method of a new substance needs to be stored in the built-in method library in time, in order to update the built-in method library in time, the method provided by the embodiment of the present invention may also provide an editing channel for the user to edit the operation parameters in the method file through the editing channel. In a specific embodiment, the user may modify the operation parameters in the method file by clicking the edit button to open the method modification interface, or the user may enter the operation parameters and the name corresponding to the new method to save by clicking the new button to open the new method new interface, so as to obtain the new method file.
In one implementation, the method file provided by the embodiment of the present invention at least includes one or more of the following units: the device comprises a summary unit, an infusion pump unit, an automatic sample injector unit, a column temperature box unit and a detector unit. The user can enter a parameter setting interface by clicking the name of each unit to edit the corresponding operating parameters, wherein the operating parameters of the liquid chromatograph at least comprise one or more of the following: acquisition time, column temperature, mobile phase flow, gradient elution parameters, detector sampling rate, maximum absorption wavelength, and autosampler parameters.
For easy understanding, the present invention also provides a schematic diagram of each unit, see fig. 4 for a schematic diagram of an abstract unit, which is an example of an agilawood-content determination for detecting the content of agarotetraol in agilawood, document mtd, the abstract unit of the method can set the collection time and whether to stop automatically, can also set the mobile phase and the mixture ratio thereof needed for detecting the tested substance in the mobile photo frame (such as acetonitrile as mobile phase a and 0.1% formic acid solution as mobile phase B), set the column specification (such as octadecylsilane bonded silica gel) needed for detecting the tested substance in the column frame, set the name and the test content (such as agilawood-content determination) of the tested substance in the description column, and set the name of the needed reference substance (such as agilawood tetraol reference substance) in other columns, so that the user can prepare the items needed for measuring the tested substance according to the setting content in the abstract unit An article.
Referring to the schematic diagram of an infusion pump unit shown in fig. 5, it is shown that the left side of the infusion pump unit can set parameters such as start time, flow rate, ratio a and ratio B in a gradient table (i.e. set gradient elution parameters), and can add, delete or sort data in a ground gradient table; the right side of the infusion pump unit can be used for setting parameters such as an idle state, a user-defined flow rate, a user-defined proportion, an upper pressure limit and a lower pressure limit. In addition, the user can set the mobile phase in the infusion pump unit, select the channel according to the requirement of the user, and input or select the name of each channel.
Referring to fig. 6, a schematic diagram of an auto sampler unit shows that parameters such as a sample injection mode, a rinsing volume, a speed of an injection pump, a height of a sample injection needle, a cleaning manner, and a number of times of cleaning can be set in the auto sampler unit, and whether to perform air-cut sampling, whether to skip a position without a sample bottle during sequential operation, whether to spit part of a washing solution before sampling, and whether to start an auto sampler can be selected in a checking manner.
Referring to fig. 7, a schematic diagram of a column oven unit shows that a constant temperature mode of the column oven can be selected and a temperature value of the column oven (i.e., a column temperature) can be set in the column oven unit; meanwhile, a user can select whether to allow the sample introduction of the column incubator when the column incubator is not balanced, stop temperature control when the column incubator is disconnected and start the column incubator in a checking mode.
The detector unit provided in the embodiment of the present invention may be an ultraviolet-visible light detector unit, and referring to a schematic diagram of an ultraviolet-visible light detector unit shown in fig. 8, it is illustrated that the detector unit may set parameters such as a detection mode (such as a single wavelength), a sampling rate, and a wavelength, as well as auto-zero at a sampling time and auto-zero at a wavelength changing time; meanwhile, a wavelength time program can be set, including the starting time and the holding time of the wavelength.
It is to be understood that fig. 2 to 8 are only schematic illustrations for easy understanding and should not be considered as limitations, and in practical applications, the search interface and the method file may contain more or less contents than those in fig. 2 to 8, and the interface arrangement may be different from that in fig. 2 to 8.
According to the liquid chromatograph analysis method provided by the embodiment of the invention, the liquid chromatograph method of the common and standardized substances related in the pharmacopoeia is built in the liquid chromatograph workstation, a user can quickly search the method content of the substance to be detected through the name, the corresponding method file in the built-in method library is opened, the corresponding chromatograph method can be generated, and the user only needs to click to operate, so that the detection working efficiency is improved to the maximum extent.
Further, a built-in method library folder is installed in a method root directory in the liquid chromatography workstation, an embodiment of the present invention further provides an operation method of a built-in method library (that is, a liquid chromatography analysis method), and referring to an operation method schematic diagram of a built-in method library shown in fig. 9, it is shown that the method mainly includes the following steps S902 to S908:
step S902: and opening a method search interface.
Specifically, the user may open the method search interface by clicking the open button, and the method search interface may be as shown in fig. 2.
Step S904: inputting keywords, searching a target method file matched with the keywords and opening the target method file.
Step S906: the target method file is sent to a liquid chromatograph.
Step S908: the liquid chromatograph runs a target method file.
The implementation principle and the generated technical effect of the operation method of the built-in method library provided by the embodiment of the invention are the same as those of the method embodiment, and for brief description, no part of the embodiment is mentioned, and reference may be made to the corresponding contents in the method embodiment.
As for the liquid chromatography analysis method provided in the foregoing embodiment, an embodiment of the present invention further provides a liquid chromatography analysis apparatus, referring to a schematic structural diagram of the liquid chromatography analysis apparatus shown in fig. 10, where the apparatus may include the following components:
an instruction receiving module 1001, configured to receive a search instruction of a user; wherein, the search instruction comprises keywords.
A searching module 1002, configured to search, from a preset built-in method library, an alternative method file matched with the keyword, so that a user selects a target method file from the alternative method files; wherein, the alternative method files are one or more; the built-in method library comprises a plurality of method files with preset operation parameters of the liquid chromatograph.
A sending module 1003, configured to send the target method file selected by the user to the liquid chromatograph, so that the liquid chromatograph detects the substance to be tested according to the operation parameters in the target method file.
When a search instruction (including a keyword) of a user is received, the liquid chromatography analysis apparatus provided in the embodiments of the present invention may search one or more candidate method files matching the keyword from a preset built-in method library (including a plurality of method files in which operation parameters of the liquid chromatograph are preset), so that the user selects a target method file from the candidate method files, and then send the target method file selected by the user to the liquid chromatograph, so that the liquid chromatograph detects a substance to be tested according to the operation parameters in the target method file. According to the device, the method files are stored in the built-in method library in advance, the operation parameters of the liquid chromatograph are set in advance in each method file, when the tested substance is detected, the target method files can be directly searched in the built-in method library and sent to the liquid chromatograph, the operation parameters are not required to be set one by one, and therefore the process of setting the substance detection method is simplified, the detection time is saved, and the detection working efficiency and accuracy are improved.
In one embodiment, the apparatus and method further include a data analysis module for receiving the chromatographic data sent by the liquid chromatograph and analyzing the chromatographic data to obtain a detection result of the substance under test.
In an embodiment, the apparatus and method further include an editing module, configured to provide an editing channel for a user, so that the user can edit the operation parameters in the method file through the editing channel.
In an embodiment, the sending module 1003 is further configured to send the target method file selected by the user to the liquid chromatograph if it is detected that the preset sending key is triggered.
In an implementation manner, the apparatus further includes an open module, configured to provide a search interface for the user to input a search instruction if it is detected that the preset open key is triggered.
The device provided by the embodiment of the present invention has the same implementation principle and technical effect as the method embodiments, and for the sake of brief description, reference may be made to the corresponding contents in the method embodiments without reference to the device embodiments.
The embodiment of the invention also provides a liquid chromatography workstation, and specifically, the electronic equipment comprises a processor and a storage device; the storage means has stored thereon a computer program which, when executed by the processor, performs the method of any of the above embodiments.
Fig. 11 is a schematic structural diagram of a liquid chromatography workstation 100 according to an embodiment of the present invention, where the liquid chromatography workstation 100 includes: a processor 1101, a memory 1102, a bus 1103 and a communication interface 1104, the processor 1101, the communication interface 1104 and the memory 1102 being connected by the bus 1103; the processor 1101 is used to execute executable modules, such as computer programs, stored in the memory 1102.
The Memory 1102 may include a high-speed Random Access Memory (RAM) and may also include a non-volatile Memory (non-volatile Memory), such as at least one disk Memory. The communication connection between the network element of the system and at least one other network element is implemented through at least one communication interface 1104 (which may be wired or wireless), and the internet, a wide area network, a local network, a metropolitan area network, and the like may be used.
The bus 1103 may be an ISA bus, PCI bus, EISA bus, or the like. The bus may be divided into an address bus, a data bus, a control bus, etc. For ease of illustration, only one double-headed arrow is shown in FIG. 11, but that does not indicate only one bus or one type of bus.
The memory 1102 is configured to store a program, and the processor 1101 executes the program after receiving an execution instruction, and the method executed by the apparatus defined by the flow disclosed in any of the foregoing embodiments of the present invention may be applied to the processor 1101, or implemented by the processor 1101.
The processor 1101 may be an integrated circuit chip having signal processing capabilities. In implementation, the steps of the above method may be performed by instructions in the form of hardware, integrated logic circuits, or software in the processor 1101. The Processor 1101 may be a general-purpose Processor, and includes a Central Processing Unit (CPU), a Network Processor (NP), and the like; the device can also be a Digital Signal Processor (DSP), an Application Specific Integrated Circuit (ASIC), a Field-Programmable Gate Array (FPGA), or other Programmable logic devices, discrete Gate or transistor logic devices, discrete hardware components. The various methods, steps and logic blocks disclosed in the embodiments of the present invention may be implemented or performed. A general purpose processor may be a microprocessor or the processor may be any conventional processor or the like. The steps of the method disclosed in connection with the embodiments of the present invention may be directly implemented by a hardware decoding processor, or implemented by a combination of hardware and software modules in the decoding processor. The software module may be located in ram, flash memory, rom, prom, or eprom, registers, etc. storage media as is well known in the art. The storage medium is located in the memory 1102, and the processor 1101 reads the information in the memory 1102 and completes the steps of the above method in combination with the hardware thereof.
The computer program product of the readable storage medium provided in the embodiment of the present invention includes a computer readable storage medium storing a program code, where instructions included in the program code may be used to execute the method described in the foregoing method embodiment, and specific implementation may refer to the foregoing method embodiment, which is not described herein again.
The functions, if implemented in the form of software functional units and sold or used as a stand-alone product, may be stored in a computer readable storage medium. Based on such understanding, the technical solution of the present invention may be embodied in the form of a software product, which is stored in a storage medium and includes instructions for causing a computer device (which may be a personal computer, a server, or a network device) to execute all or part of the steps of the method according to the embodiments of the present invention. And the aforementioned storage medium includes: a U-disk, a removable hard disk, a Read-Only Memory (ROM), a Random Access Memory (RAM), a magnetic disk or an optical disk, and other various media capable of storing program codes.
Finally, it should be noted that: the above-mentioned embodiments are only specific embodiments of the present invention, which are used for illustrating the technical solutions of the present invention and not for limiting the same, and the protection scope of the present invention is not limited thereto, although the present invention is described in detail with reference to the foregoing embodiments, those skilled in the art should understand that: any person skilled in the art can modify or easily conceive the technical solutions described in the foregoing embodiments or equivalent substitutes for some technical features within the technical scope of the present disclosure; such modifications, changes or substitutions do not depart from the spirit and scope of the embodiments of the present invention, and they should be construed as being included therein. Therefore, the protection scope of the present invention shall be subject to the protection scope of the claims.
Claims (10)
1. A method of liquid chromatography comprising:
receiving a search instruction of a user; wherein the search instruction comprises a keyword;
searching an alternative method file matched with the keyword from a preset built-in method library so that the user can select a target method file from the alternative method files; wherein, the alternative method files are one or more; the built-in method library comprises a plurality of method files with preset operation parameters of the liquid chromatograph;
and sending the target method file selected by the user to the liquid chromatograph so that the liquid chromatograph detects the tested substance according to the operating parameters in the target method file.
2. The liquid chromatography method of claim 1, further comprising:
and receiving chromatographic data sent by the liquid chromatograph, and analyzing the chromatographic data to obtain a detection result of the tested substance.
3. The liquid chromatography method of claim 1, further comprising:
and providing an editing channel for the user so that the user can edit the operation parameters in the method file through the editing channel.
4. The liquid chromatography analysis method according to claim 1, wherein the step of transmitting the target method file selected by the user to the liquid chromatograph includes:
and if the preset sending key is triggered, sending the target method file selected by the user to the liquid chromatograph.
5. The liquid chromatography analysis method of claim 1, wherein the step of receiving a search instruction from a user is preceded by the step of:
and if the preset opening key is triggered, providing a search interface for the user so that the user can input the search instruction.
6. The liquid chromatography analysis method of claim 1, wherein the method file comprises at least one or more of the following units: the device comprises a summary unit, an infusion pump unit, an automatic sample injector unit, a column temperature box unit and a detector unit.
7. The liquid chromatography analysis method of claim 1, wherein the liquid chromatograph operating parameters include at least one or more of: acquisition time, column temperature, mobile phase flow, gradient elution parameters, detector sampling rate, maximum absorption wavelength, and autosampler parameters.
8. A liquid chromatography apparatus, comprising:
the instruction receiving module is used for receiving a search instruction of a user; wherein the search instruction comprises a keyword;
the searching module is used for searching the alternative method files matched with the keywords from a preset built-in method library so that the user can select the target method files from the alternative method files; wherein, the alternative method files are one or more; the built-in method library comprises a plurality of method files with preset operation parameters of the liquid chromatograph;
and the sending module is used for sending the target method file selected by the user to the liquid chromatograph so that the liquid chromatograph detects the tested substance according to the operating parameters in the target method file.
9. A liquid chromatography workstation comprising a processor and a memory, the memory storing computer executable instructions executable by the processor, the processor executing the computer executable instructions to perform the steps of the method of any one of claims 1 to 7.
10. A computer-readable storage medium, on which a computer program is stored, which, when being executed by a processor, carries out the steps of the method according to any one of the claims 1 to 7.
Priority Applications (1)
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| CN112863615A (en) * | 2021-02-25 | 2021-05-28 | 华谱科仪(大连)科技有限公司 | Chromatographic analysis system based on double-database architecture |
| CN114088847A (en) * | 2022-01-19 | 2022-02-25 | 华谱科仪(北京)科技有限公司 | Sample determination method and device based on chromatographic analysis, storage medium and server |
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