CN112142874A - Pressure device for heparin sodium processing - Google Patents

Pressure device for heparin sodium processing Download PDF

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Publication number
CN112142874A
CN112142874A CN202011129321.3A CN202011129321A CN112142874A CN 112142874 A CN112142874 A CN 112142874A CN 202011129321 A CN202011129321 A CN 202011129321A CN 112142874 A CN112142874 A CN 112142874A
Authority
CN
China
Prior art keywords
chamber
heparin sodium
rod
plunger
block
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202011129321.3A
Other languages
Chinese (zh)
Inventor
钱成
季志娟
丁佐爱
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Jiangsu Qianmu Biotechnology Co ltd
Original Assignee
Jiangsu Qianmu Biotechnology Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jiangsu Qianmu Biotechnology Co ltd filed Critical Jiangsu Qianmu Biotechnology Co ltd
Priority to CN202011129321.3A priority Critical patent/CN112142874A/en
Publication of CN112142874A publication Critical patent/CN112142874A/en
Pending legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D29/00Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups B01D24/00 - B01D27/00; Filtering elements therefor
    • B01D29/01Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups B01D24/00 - B01D27/00; Filtering elements therefor with flat filtering elements
    • B01D29/03Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups B01D24/00 - B01D27/00; Filtering elements therefor with flat filtering elements self-supporting
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D29/00Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups B01D24/00 - B01D27/00; Filtering elements therefor
    • B01D29/62Regenerating the filter material in the filter
    • B01D29/70Regenerating the filter material in the filter by forces created by movement of the filter element
    • B01D29/72Regenerating the filter material in the filter by forces created by movement of the filter element involving vibrations
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D29/00Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups B01D24/00 - B01D27/00; Filtering elements therefor
    • B01D29/76Handling the filter cake in the filter for purposes other than for regenerating
    • B01D29/80Handling the filter cake in the filter for purposes other than for regenerating for drying
    • B01D29/82Handling the filter cake in the filter for purposes other than for regenerating for drying by compression
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D35/00Filtering devices having features not specifically covered by groups B01D24/00 - B01D33/00, or for applications not specifically covered by groups B01D24/00 - B01D33/00; Auxiliary devices for filtration; Filter housing constructions
    • B01D35/30Filter housing constructions

Abstract

The invention discloses a pressurizing device for processing heparin sodium, which relates to the field of processing heparin sodium and comprises a pressurizing chamber, wherein one side of the pressurizing chamber is provided with a filtering chamber, a filtering plate is arranged in the filtering chamber, a plunger block is arranged in the pressurizing chamber, the top side of the plunger block is fixedly provided with a plunger push rod, one side of the pressurizing chamber is fixedly provided with a fixed block, and the bottom side of the fixed block is rotatably provided with a rotating rod. According to the invention, the plunger push rod can drive the connecting rod to move in the downward movement pressurizing process, so that the sliding column is driven to move, the sliding column moves under the action of the threaded sliding groove, the rotating rod can be driven to rotate, the rotating rod rotates to drive the knocking cam to rotate, the filter plate is knocked continuously, the blockage on the filter plate is vibrated and can be separated from the filter plate, the heparin sodium liquid in the raw material is rapidly filtered, and the problems of slow filtering and insufficient filtering caused by blockage are effectively avoided.

Description

Pressure device for heparin sodium processing
Technical Field
The invention relates to the technical field of heparin sodium processing, in particular to a pressurizing device for heparin sodium processing.
Background
Heparin sodium can interfere with many links of the blood coagulation process and has the function of anticoagulation in vivo and in vitro. The mechanism of action is complex, and the inhibition of activated blood coagulation factors II, IX, X, XI and XII by the latter is enhanced mainly by binding to antithrombin III (AT-III), which later involves preventing platelet aggregation and destruction, preventing the formation of thromboplastin, preventing prothrombin from becoming thrombin, inhibiting thrombin, thereby preventing fibrinogen from becoming fibrin, and thus exerting anticoagulation.
Through the retrieval, the patent that publication number is CN210699007U discloses an extract pig source heparin sodium and use flat-plate separation filter equipment, including the filter, the shape of filter is L type structure and inside is the cavity formula structure, the vertical end left side intercommunication of filter has the pan feeding pipe, through the pressurized mode, extrudees the filtration to inside extraction pig source heparin sodium, but at filterable in-process, has more float dress thing on the raw materials of extraction, when carrying out the pressurization and filtering, can pile up on the filter screen to cause the jam, can not be quick filter the raw materials and filter inadequately, consequently need a pressure device that heparin sodium processing used to satisfy people's demand.
Disclosure of Invention
The invention aims to provide a pressurizing device for processing heparin sodium, which aims to solve the problems that in the filtering process, a large amount of floating objects exist in extracted raw materials, and the extracted raw materials are accumulated on a filter screen during pressure filtering, so that blockage is caused, the raw materials cannot be quickly filtered, and the filtering is insufficient.
In order to achieve the purpose, the invention provides the following technical scheme: the utility model provides a pressure device that heparin sodium processing used, includes the pressurized chamber, and one side of pressurized chamber is equipped with the filter chamber, is equipped with the filter in the filter chamber, is equipped with the plunger piece in the pressurized chamber, and the top side fixed mounting of plunger piece has the plunger push rod, one side fixed mounting of pressurized chamber has the fixed block, and the bottom side of fixed block is rotated and is installed the bull stick, has seted up the commentaries on classics hole on one side inner wall of filter chamber, and the bottom of bull stick is rotated and is run through commentaries on classics hole and fixed mounting.
Preferably, the top side of fixed block has been seted up and has been removed the hole, removes downthehole movable mounting and have a drive pole, and outside the both ends of drive pole all extended to removing the hole, the top fixed mounting of drive pole had the connecting rod, and the one end fixed mounting of connecting rod is on one side of plunger push rod.
Preferably, a threaded sliding groove is formed in the rotating rod, a sliding column is fixedly mounted on one side of the driving rod, and the sliding column is slidably mounted in the sliding groove.
Preferably, the bottom side of fixed block has seted up protruding type rotary trough, and the top fixed mounting of bull stick has protruding type rotatory piece, and protruding type rotatory piece rotates to be installed at protruding type rotary trough.
Preferably, a sealing plate is fixedly mounted on the top side of the plunger block, a movable hole is formed in the inner wall of the top side of the pressurizing chamber, the sealing plate movably penetrates through the movable hole, a feeding pipe is arranged on one side of the pressurizing chamber and communicated with the pressurizing chamber, and the sealing plate is matched with the feeding pipe.
Preferably, the top end of the plunger push rod is fixedly provided with a lower pressure rod, and the lower pressure rod is provided with a protective sleeve.
Preferably, discharge pipes are arranged on the bottom sides of the pressurizing chamber and the filtering chamber, and support frames are fixedly arranged on the bottom sides of the pressurizing chamber and the filtering chamber.
The invention has the beneficial effects that:
according to the invention, the plunger push rod can drive the connecting rod to move in the downward moving and pressurizing process, the connecting rod moves to drive the driving rod to move in the moving hole, the driving rod moves to drive the sliding column to move, the sliding column moves under the action of the threaded sliding groove and can drive the rotating rod to rotate, the rotating rod rotates to drive the knocking cam to rotate and continuously knock the filter plate, so that a blockage on the filter plate is vibrated and can be separated from the filter plate, the heparin sodium liquid in the raw material is rapidly filtered, and the problems of slow filtering and insufficient filtering caused by blockage are effectively avoided.
In the invention, certain raw materials are remained in the feeding pipe in the extrusion process, the raw materials flow when the plunger block moves downwards for pressurization, and the arranged sealing plate can block the raw materials in the feeding pipe, so that the problems of corrosion and inconvenience in cleaning caused by the fact that the raw materials flow to the top side of the plunger block are avoided.
Drawings
Fig. 1 is a left-view three-dimensional structural schematic diagram of a pressurizing device for heparin sodium processing according to the present invention.
Fig. 2 is a schematic structural diagram of a pressurizing device for heparin sodium processing according to the present invention.
Fig. 3 is a schematic structural view of a cross section of a pressurizing device used for heparin sodium processing according to the present invention.
Fig. 4 is a schematic structural view of a portion a in fig. 3 of a pressurizing device for heparin sodium processing according to the present invention.
In the figure: 1. a pressurized chamber; 2. a filtering chamber; 3. a filter plate; 4. a feeding pipe; 5. a plunger block; 6. a plunger push rod; 7. a lower pressure lever; 8. a sealing plate; 9. a movable hole; 10. a fixed block; 11. a rotating rod; 12. a male rotating block; 13. hole turning; 14. knocking the cam; 15. a connecting rod; 16. driving the rod; 17. moving the hole; 18. a sliding post; 19. a sliding groove; 20. and (4) discharging the pipe.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments.
Referring to fig. 1-4, a pressurizing device for heparin sodium processing comprises a pressurizing chamber 1, wherein one side of the pressurizing chamber 1 is provided with a filtering chamber 2, a filtering plate 3 is arranged in the filtering chamber 2, a plunger block 5 is arranged in the pressurizing chamber 1, a plunger push rod 6 is fixedly arranged on the top side of the plunger block 5, a fixed block 10 is fixedly arranged on one side of the pressurizing chamber 1, a rotating rod 11 is rotatably arranged on the bottom side of the fixed block 10, a rotating hole 13 is formed in the inner wall of the top side of the filtering chamber 2, the bottom end of the rotating rod 11 rotatably penetrates through the rotating hole 13 and is fixedly provided with a knocking cam 14, the knocking cam 14 is matched with the filtering plate 3, a worker presses a pressing rod 7 downwards, the pressing rod 7 moves to drive the plunger push rod 6 to move, the plunger push rod 6, the pressure in the pressure chamber 1 is increased, so that the heparin sodium in the raw material can be extracted quickly.
In the invention, a moving hole 17 is formed in the top side of the fixed block 10, a driving rod 16 is movably installed in the moving hole 17, two ends of the driving rod 16 extend out of the moving hole 17, a connecting rod 15 is fixedly installed at the top end of the driving rod 16, one end of the connecting rod 15 is fixedly installed on one side of the plunger push rod 6, and the driving rod 16 is convenient to move on the fixed block 10.
In the invention, a threaded sliding groove 19 is formed in the rotating rod 11, a sliding column 18 is fixedly arranged on one side of the driving rod 16, the sliding column 18 is slidably arranged in the sliding groove 19, and the sliding column 18 can drive the rotating rod 11 to rotate under the action of the threaded sliding groove 19.
In the invention, a convex rotating groove is formed at the bottom side of the fixed block 10, a convex rotating block 12 is fixedly arranged at the top end of the rotating rod 11, and the convex rotating block 12 is rotatably arranged in the convex rotating groove, so that the rotating rod 11 can conveniently rotate on the fixed block 10.
According to the invention, a sealing plate 8 is fixedly arranged on the top side of a plunger block 5, a movable hole 9 is formed in the inner wall of the top side of a pressure chamber 1, the sealing plate 8 movably penetrates through the movable hole 9, a feeding pipe 4 is arranged on one side of the pressure chamber 1, the feeding pipe 4 is communicated with the pressure chamber 1, the sealing plate 8 and the feeding pipe 4 are matched with each other, after the feeding pipe 4 feeds raw materials, certain raw materials are remained in the feeding pipe 4 in the extrusion process, and when the plunger block 5 moves downwards for pressurization, the arranged sealing plate 8 can block the raw materials in the feeding pipe 4, so that the problems of corrosion and inconvenience in cleaning caused by the fact that the raw materials flow to the top side of the plunger block 5 are.
According to the invention, the top end of the plunger push rod 6 is fixedly provided with the lower pressure rod 7, and the lower pressure rod 7 is provided with the protective sleeve, so that the plunger push rod 6 can be moved better.
In the invention, discharge pipes 20 are arranged at the bottom sides of the compression chamber 1 and the filter chamber 2, and support frames are fixedly arranged at the bottom sides of the compression chamber 1 and the filter chamber 2.
This practical theory of operation:
in the invention, a worker presses a pressing rod 7 downwards, the pressing rod 7 moves to drive a plunger push rod 6 to move, the plunger push rod 6 moves to drive a plunger block 5 to move, the plunger block 5 presses the pressure chamber 1 after moving upwards, so that heparin sodium in raw materials can be rapidly extracted, residues in the raw materials can block a filter plate 3 in the extraction process, the plunger push rod 6 drives a connecting rod 15 to move in the downward moving and pressurizing process, the connecting rod 15 moves to drive a driving rod 16 to move in a moving hole 17, the driving rod 16 moves to drive a sliding column 18 to move, the sliding column 18 moves under the action of a threaded sliding groove 19 and can drive a rotating rod 11 to rotate, the rotating rod 11 rotates to drive a convex rotating block 12 to rotate in the convex rotating groove, the rotating rod 11 rotates to drive a knocking cam 14 to rotate, and the filter plate 3 is continuously knocked, make the plug on the filter 3 receive vibrations, can break away from filter 3, heparin sodium liquid in the raw materials carries out quick quilt and filters, effectively avoid causing the filtration slow because of blockking up, filter insufficient problem, the extrusion in-process, still can leave certain raw materials in the pan feeding pipe 4, plunger piece 5 is when the downward movement pressurization, the raw materials can flow, the closing plate 8 of setting, can carry out the shutoff with the raw materials in the pan feeding pipe 4, avoid flowing to on the top side of plunger piece 5, cause the problem of corruption and the clearance of not being convenient for, high durability and convenient use.
The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be considered to be within the technical scope of the present invention, and the technical solutions and the inventive concepts thereof according to the present invention should be equivalent or changed within the scope of the present invention.

Claims (7)

1. The utility model provides a pressure device that heparin sodium processing was used, includes pressurized chamber (1), and one side of pressurized chamber (1) is equipped with filter chamber (2), is equipped with filter (3) in filter chamber (2), is equipped with plunger piece (5) in pressurized chamber (1), and the top side fixed mounting of plunger piece (5) has plunger push rod (6), its characterized in that: one side fixed mounting of pressurized chamber (1) has fixed block (10), and the bottom side of fixed block (10) is rotated and is installed bull stick (11), has seted up on the top side inner wall of filter chamber (2) and has been changeed hole (13), and the bottom of bull stick (11) is rotated and is run through commentaries on classics hole (13) and fixed mounting has and strikes cam (14), strikes cam (14) and filter (3) looks adaptation.
2. The pressurization device for heparin sodium processing according to claim 1, wherein: removal hole (17) have been seted up to the top side of fixed block (10), and movable mounting has drive rod (16) in removal hole (17), and outside the both ends of drive rod (16) all extended to removal hole (17), the top fixed mounting of drive rod (16) had connecting rod (15), and the one end fixed mounting of connecting rod (15) is on one side of plunger push rod (6).
3. The pressurization device for heparin sodium processing according to claim 1, wherein: a threaded sliding groove (19) is formed in the rotating rod (11), a sliding column (18) is fixedly mounted on one side of the driving rod (16), and the sliding column (18) is slidably mounted in the sliding groove (19).
4. The pressurization device for heparin sodium processing according to claim 1, wherein: the bottom side of fixed block (10) has seted up protruding type rotary trough, and the top fixed mounting of bull stick (11) has protruding type rotatory block (12), and protruding type rotatory block (12) rotate to be installed in protruding type rotary trough.
5. The pressurization device for heparin sodium processing according to claim 1, wherein: the plunger piston is characterized in that a sealing plate (8) is fixedly mounted on the top side of the plunger piston block (5), a movable hole (9) is formed in the inner wall of the top side of the pressurizing chamber (1), the sealing plate (8) movably penetrates through the movable hole (9), a feeding pipe (4) is arranged on one side of the pressurizing chamber (1), the feeding pipe (4) is communicated with the pressurizing chamber (1), and the sealing plate (8) is matched with the feeding pipe (4).
6. The pressurization device for heparin sodium processing according to claim 1, wherein: the top end of the plunger push rod (6) is fixedly provided with a lower pressing rod (7), and the lower pressing rod (7) is provided with a protective sleeve.
7. The pressurization device for heparin sodium processing according to claim 1, wherein: the bottom sides of the pressurizing chamber (1) and the filtering chamber (2) are both provided with a discharging pipe (20), and the bottom sides of the pressurizing chamber (1) and the filtering chamber (2) are both fixedly provided with a supporting frame.
CN202011129321.3A 2020-10-21 2020-10-21 Pressure device for heparin sodium processing Pending CN112142874A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202011129321.3A CN112142874A (en) 2020-10-21 2020-10-21 Pressure device for heparin sodium processing

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202011129321.3A CN112142874A (en) 2020-10-21 2020-10-21 Pressure device for heparin sodium processing

Publications (1)

Publication Number Publication Date
CN112142874A true CN112142874A (en) 2020-12-29

Family

ID=73954235

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202011129321.3A Pending CN112142874A (en) 2020-10-21 2020-10-21 Pressure device for heparin sodium processing

Country Status (1)

Country Link
CN (1) CN112142874A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113041679A (en) * 2021-03-09 2021-06-29 吴珍理 Microbial pesticide preparation sprays filter equipment

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113041679A (en) * 2021-03-09 2021-06-29 吴珍理 Microbial pesticide preparation sprays filter equipment
CN113041679B (en) * 2021-03-09 2023-09-01 吴珍理 Microbial pesticide preparation sprays filter equipment

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