CN112126184A - High polymer optical fiber endoscope objective long-acting antibacterial outer body for medical communication equipment and preparation method thereof - Google Patents
High polymer optical fiber endoscope objective long-acting antibacterial outer body for medical communication equipment and preparation method thereof Download PDFInfo
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- CN112126184A CN112126184A CN202011016354.7A CN202011016354A CN112126184A CN 112126184 A CN112126184 A CN 112126184A CN 202011016354 A CN202011016354 A CN 202011016354A CN 112126184 A CN112126184 A CN 112126184A
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Classifications
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J3/00—Processes of treating or compounding macromolecular substances
- C08J3/20—Compounding polymers with additives, e.g. colouring
- C08J3/22—Compounding polymers with additives, e.g. colouring using masterbatch techniques
- C08J3/226—Compounding polymers with additives, e.g. colouring using masterbatch techniques using a polymer as a carrier
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/00131—Accessories for endoscopes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/00142—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with means for preventing contamination, e.g. by using a sanitary sheath
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F2/00—Processes of polymerisation
- C08F2/46—Polymerisation initiated by wave energy or particle radiation
- C08F2/48—Polymerisation initiated by wave energy or particle radiation by ultraviolet or visible light
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
- C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
- C08F220/52—Amides or imides
- C08F220/54—Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2433/00—Characterised by the use of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides, or nitriles thereof; Derivatives of such polymers
- C08J2433/04—Characterised by the use of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides, or nitriles thereof; Derivatives of such polymers esters
- C08J2433/06—Characterised by the use of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides, or nitriles thereof; Derivatives of such polymers esters of esters containing only carbon, hydrogen, and oxygen, the oxygen atom being present only as part of the carboxyl radical
- C08J2433/10—Homopolymers or copolymers of methacrylic acid esters
- C08J2433/12—Homopolymers or copolymers of methyl methacrylate
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- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2433/00—Characterised by the use of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides, or nitriles thereof; Derivatives of such polymers
- C08J2433/24—Homopolymers or copolymers of amides or imides
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- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
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- C08K5/0058—Biocides
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K5/00—Use of organic ingredients
- C08K5/54—Silicon-containing compounds
- C08K5/544—Silicon-containing compounds containing nitrogen
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Abstract
The invention discloses a high polymer optical fiber endoscope objective lens outer body for long-acting medical communication equipment and a preparation method thereof, which comprises the steps of adding 5-20% by weight of novel antibacterial mother powder into an objective lens outer body raw material, and preparing the objective lens outer body according to the prior art. The invention relates to a long-acting medical communication device which adds antibacterial mother powder into the outer body of a high polymer optical fiber endoscope objective lens, wherein the antibacterial mother powder is prepared by photocatalytic polymerization of natural cannabinoids, catechin and organic amide. The composite material has good dispersibility and compatibility when compounded with plastic resin, shows excellent aging resistance and better mechanical property and hand feeling when added into a high polymer product, greatly prolongs the service life, has the functions of resisting common pathogenic bacteria, inhibiting drug-resistant pathogenic bacteria, has high efficiency and lasting water washing resistance, plays the roles of purifying the environment, eliminating peculiar smell, self-cleaning and health care, does not pollute the environment and has no side effect on human bodies, and is beneficial to people to obtain more health benefits.
Description
Technical Field
The invention belongs to the field of optical fiber communication and functional new material products, and particularly relates to a long-acting antibacterial outer body of an objective lens on a high polymer optical fiber endoscope probe for medical communication equipment and a preparation method thereof.
Background
The use frequency and the variety of high polymer products such as the outer body of an optical fiber endoscope probe objective lens, textiles, other sheets, blow molding and other products are higher and higher along with the social progress. However, these products do not have an antibacterial function, become messy over time on the outer surface of the product, and are prone to develop off-flavors. Especially, the endoscope and other products are implanted into the human body for a long time or are used very frequently, so that various harmful bacteria, mold and the like are easy to breed or propagate, and the endoscope becomes a propagation source, and brings great trouble to the health of users.
In view of the above, in recent years, researches on antibacterial properties of polymer objective lens outer products have been increasingly conducted at home and abroad, and the antibacterial properties are mainly obtained by adding a small amount of antibacterial agent to common plastics. According to the searched literature, the current antibacterial agents are mainly divided into three series of single inorganic, organic and natural according to the structure. The inorganic antibacterial agent is prepared by taking metal ions such as silver, copper, zinc and the like as an antibacterial agent and taking porous inorganic non-metallic materials such as phosphate, bentonite and the like as carriers, has strong heat resistance, but has high price, environmental protection and washing resistance, and can cause negative effects on the liver of a human body when being used for a long time and touching the product containing the metal ions such as silver, copper, zinc and the like.
The organic antibacterial agent comprises quaternary ammonium salts, imidazoles, pyridines, organic metals and the like, has high sterilization speed and obvious antibacterial effect, is easy to generate drug resistance, has poor thermal stability, can not be implanted into macromolecular fibers, has short antibacterial persistence and high toxicity, and thus brings new health hidden troubles to people. Compared with the prior art, the natural antibacterial agent is extracted from plants, animals or organisms, has wide sources and low cost, has the advantages of safety, no toxicity, rich nutrition and health care components, difficult generation of drug resistance, environmental friendliness and the like, and is more and more valued by people in application and research.
However, natural antibacterial agents are usually extracted from a plant, an animal or a living being, and have the problems of single antibacterial component, narrow antibacterial range, poor compatibility with plastics, agglomeration, uneven dispersion and the like, and the antibacterial component is easy to separate out in the use process, the antibacterial effect cannot be lasting, the drug resistance of pathogenic bacteria of the product to the antibacterial component is easy, and the antibacterial agents have no effect on pathogenic bacteria with drug resistance, such as methicillin-resistant staphylococcus aureus.
Disclosure of Invention
Aiming at the technical problems, the invention provides a long-acting antibacterial outer body of a high polymer optical fiber endoscope objective lens for medical communication equipment and a preparation method thereof, wherein the added antibacterial mother powder is prepared by polymerizing various natural non-psychoactive compounds into an antibacterial polymer macromolecule, and the antibacterial polymer macromolecule is compounded with polyolefin plastic resin, has good dispersibility and compatibility, shows excellent ageing resistance, biocompatibility, overflow resistance and better mechanical property when added into products such as high polymers and the like, greatly prolongs the service life, has the functions of resisting common pathogenic bacteria, inhibiting drug-resistant pathogenic bacteria, has high efficiency and long-lasting water washing resistance, has the functions of purifying environment, eliminating peculiar smell, self-cleaning and health care, does not pollute the environment and has no side effect on human bodies, and is beneficial to people to obtain more health benefits.
The invention provides a long-acting antibacterial outer body of a high polymer optical fiber endoscope objective lens for medical communication equipment, which comprises 5-20% by weight of antibacterial mother powder in raw materials.
Preferably, the antibacterial mother powder comprises the following raw materials in percentage by weight: 1-4% of antibacterial agent No. 3 of antibacterial mother powder, 0.1-1% of lubricant, 0.1-0.5% of coupling agent and the balance polymethyl methacrylate PMMA.
Preferably, the coupling agent is prepared by the following method:
(1) mixing gamma-aminopropyltriethoxysilane and cinnamic acid according to the mol ratio of (2-5):1 to obtain a mixture, adding ethanol with the mass of 4-6 times of that of the mixture, and stirring at the temperature of 20-30 ℃ and 200 revolutions per minute for 10-20 minutes to obtain a mixed solution A;
(2) adding 98 mass percent of concentrated sulfuric acid into the mixed solution A, heating to 60-80 ℃, and stirring for 8-12 hours at the speed of 100-;
(3) and (3) concentrating the mixed solution B under reduced pressure at the pressure of 60Pa and the temperature of 40-60 ℃ until crystals are separated out, standing at 10-20 ℃ for 1-3 hours, filtering through a 300-mesh filter cloth, and drying the solid in a vacuum drying oven at 40-60 ℃ until the weight is constant to obtain the coupling agent.
Preferably, the antibacterial mother powder No. 3 antibacterial agent is prepared by the following method:
50-80 parts of methyl methacrylate (purified before use), 100-150 parts of PEAm powder (N-phenylethylacrylamide, AR, CAS:2210-24-4), 50-80 parts of catechin (anhydrous captin, 98%, CAS: 7259-85-4), 3-6 parts of Eucalyptus oil (99%), and 5-8 parts of ZnTPP/TiO2 composite photocatalyst, wherein the above components are added into a thickened glass reaction kettle, protected by nitrogen, and reacted for 36 hours at the temperature of 130 ℃ under the irradiation of a light source with the wavelength of 525 nm. After the reaction, the obtained reactant is subjected to nitrogen flushing 3 times by using nitrogen with the volume of about 20 reaction kettles each time in the same reaction kettle at the temperature of 120 ℃ under the condition of intermittent vacuum pumping. Then washing and soaking the obtained reactant in 10 times of deionized water for ten minutes, repeating for 3 times, and finally drying the reactant in vacuum at the temperature of 95 ℃ for 5 hours to obtain a polymer, grinding the polymer into powder with the diameter less than 0.3um under the condition of liquid nitrogen, and storing the powder for later use.
Preferably, the ZnTPP/TiO2The preparation method of the nano photocatalyst comprises the following steps:
pyrrole (AR, CAS-109-97-7, C)4H5N10-20 parts, benzaldehyde (AR)10-20 parts, propionic Acid (AR) (PH 5)20-50 parts, magnetic stirring for 20 minutes, adding Zn (OAc)2-2H22-5 parts of O ethanol solution (AR), continuously stirring for 20 minutes, slowly adding 200 parts of butyl titanate 100-one to form uniform, stable and dark red brown sol, standing for 14 daysThe sol becomes xerogel, vacuum drying is carried out for 12 to 16 hours at the temperature of 50 ℃, the obtained solid is ground for 2 hours at low temperature, and finally sintering is carried out for 10 hours at the temperature of 400 ℃. Obtaining ZnTPP/TiO2A composite photocatalyst.
The invention also provides a preparation method of the long-acting antibacterial outer body of the high polymer optical fiber endoscope objective lens for the medical communication equipment, which comprises the steps of adding 5-20% by weight of antibacterial mother powder into the raw material of the outer body of the objective lens, and preparing the outer body of the objective lens according to the prior art.
In the technical scheme, the invention provides a technology for a long-acting antibacterial agent which is insoluble in water, does not fall off and has long-acting antibacterial effect. The essence of the technology is to completely replace silver or nano silver and use a compound organic antibacterial agent formula. According to the formula technology, a plurality of antibacterial agents are combined into a mixed powder, namely, antibacterial mother powder No. 3, a dispersing agent is added, the antibacterial mother powder No. 3 can achieve the characteristic of no shedding after being solidified, and the antibacterial mother powder No. 3 can achieve the long-acting antibacterial function.
The antibacterial mechanism of the organic antibacterial agent is mainly that the organic antibacterial agent is combined with anions on the surface of a cell membrane of the pathogenic bacteria or reacts with sulfydryl so as to destroy the structure of protein or influence the synthesis of a biological membrane, thereby inhibiting the propagation of the pathogenic bacteria. In general, the mechanism of action of organic antibacterial agents is summarized as: (1) acting on protease or other bioactive substances required by biochemical reaction; (2) acting on DNA of genetic material or other genetic micropowder structure; (3) acting on the biological membrane system or cell wall.
The invention adopts the synergistic cooperation of all the substances to adsorb pathogenic bacteria with negative charges, destroy the cell wall mechanism of the bacteria, cause the contents to leak and inhibit the actions of the pathogenic bacteria such as oxidase and dehydrogenase; it also can remove lipid substances in pathogenic bacteria membrane and denature protein; can also interfere the mitosis process of pathogenic bacteria, inhibit the formation of spindle, and influence the cell division process of pathogenic bacteria.
The invention has the beneficial effects that: the invention uses a plurality of mental activity-free antibacterial agents to react and combine into a mixed powder, named as antibacterial mother powder No. 3, and a dispersant is added, so that the antibacterial agent achieves the characteristic of permanent non-shedding after being solidified and can achieve the long-acting antibacterial function.
The antibacterial mother powder is prepared by reacting various non-psychoactive compounds, has good dispersity and compatibility when compounded with polymethyl methacrylate resin, shows excellent anti-aging capability and better mechanical property when added into products such as polymethyl methacrylate resin and the like, greatly prolongs the service life, has the functions of resisting common pathogenic bacteria and inhibiting drug-resistant pathogenic bacteria, is efficient and durable in washing, has the functions of purifying oral cavity, eliminating peculiar smell, self-cleaning and health care, does not pollute the environment and has no side effect on human bodies, and is beneficial to obtaining more health benefits for people.
Detailed Description
In the present invention, all the equipment and materials are commercially available or commonly used in the art, and the methods in the following examples are conventional in the art unless otherwise specified.
Polymethyl methacrylate resin powder, commercially available product.
Methyl methacrylate (purified before use).
ZnTPP/TiO2Nano photocatalyst/functional agent, self-made.
Silver ion antibacterial mother powder, commercially available silver ion antibacterial mother powder, model HFK.
And (3) antibacterial testing: according to the ISO22196:2011 standard. The experimental species were E.coli (ATCC8739), methicillin-resistant Staphylococcus aureus (ATCC33591), Staphylococcus aureus (ATCC6538), Candida albicans (ATCC10231), and Klebsiella pneumoniae (ATCC 4319).
Warm water immersion experiment: the specimen obtained in the objective lens outer body sheet experiment was perforated with a small hole at one end thereof so that the specimen was fastened with a glass weight with a cotton thread and could be immersed in water. Placing the sample in a 1000ml beaker, adding about 1000ml of distilled water, heating the water to 50 ℃ with occasional stirring, and standing for 168 hours; then, 1000ml of distilled water was replaced with a new one, heated to 50 ℃ and left for 168 hours. The experiment was repeated for 4320 hours (180 days). After 180 days, the swatches were removed, air dried, and tested for antimicrobial activity.
Objective lens outer body sheet experiment:
example 1
5.0 percent of antibacterial agent No. 3 of antibacterial mother powder, 50 percent of methyl methacrylate and catalyst/functional agent (ZnTPP/TiO)2BPO 8:2) 2%, the balance being polymethyl methacrylate resin powder.
The antibacterial agent No. 3 of the antibacterial mother powder is prepared by the following method:
50-80 parts of methyl methacrylate (purified before use), 100-150 parts of PEAm powder (N-phenylethylacrylamide, AR, CAS:2210-24-4), 50-80 parts of catechin (anhydrous captin, 98%, CAS: 7259-85-4), 3-6 parts of Eucalyptus oil (99%), and 5-8 parts of ZnTPP/TiO2 composite photocatalyst, wherein the above components are added into a thickened glass reaction kettle, protected by nitrogen, and reacted for 36 hours at the temperature of 130 ℃ under the irradiation of a light source with the wavelength of 525 nm. After the reaction, the obtained polymer was subjected to nitrogen purging 3 times with about 20 reactor volumes of nitrogen each time at 120 ℃ in the same reactor under intermittent vacuum. Then washing and soaking the obtained reactant in 10 times of deionized water for ten minutes, repeating for 3 times, and finally drying the reactant in vacuum at the temperature of 95 ℃ for 5 hours to obtain a polymer, grinding the polymer into powder with the diameter less than 0.3um under the condition of liquid nitrogen, and storing the powder for later use.
ZnTPP/TiO2The preparation method of the nano photocatalyst comprises the following steps:
pyrrole (AR, CAS-109-97-7, C)4H5N)10-20 parts, benzaldehyde (AR,) 10-20 parts, propionic Acid (AR) (PH 5)20-50 parts, magnetic stirring for 20 minutes, adding Zn (OAc)2-2H22-5 parts of O ethanol solution (AR), continuously stirring for 20 minutes, slowly adding 200 parts of butyl titanate 100-one to form uniform, stable and dark red brown sol, standing for 14 days to obtain dry sol, vacuum drying at 50 ℃ for 12-16 hours to obtain solid, grinding at low temperature for 2 hours, and finally sintering at 400 ℃ for 10 hours. Obtaining ZnTPP/TiO2A composite photocatalyst.
The raw materials are mixed according to the formula amount and put into a high-speed stirrer (provided with a cooling device). Agitation was started at a low speed (about 50-80RPM) and after three minutes the speed was gradually increased to a high speed (about 400RPM) and agitation was continued for 3 minutes. During which time the mixture temperature was kept at no more than 45 ℃. After removing the air bubbles from the mixture in a vacuum oven, the mixture was carefully poured onto ultra high molecular weight polyethylene sheet to form a coating of about 3mm thickness.
After the bubbles of the coating are further removed, the coating is polymerized for 8 hours under the radiation of a 525nm light source at room temperature, and then polymerized for 12 hours under the vacuum pumping conditions of 90 ℃, 6 hours and 110 ℃. The polymerized sample piece was peeled from the polyethylene sheet with the reverse side and irradiated with a 525nm light source at room temperature for an additional 8 hours. The sample is cut into pieces with length and width of 6cm and X6 cm for storage.
Example 2
10.0 percent of antibacterial agent No. 3 of antibacterial mother powder, 50 percent of methyl methacrylate and catalyst (ZnTPP/TiO)2BPO 8:2) 2%, the balance being polymethyl methacrylate resin powder.
The mixture was placed in a high speed mixer (equipped with a cooling device). Agitation was started at a low speed (about 50-80RPM) and after three minutes the speed was gradually increased to a high speed (about 400RPM) and agitation was continued for 3 minutes. During which time the mixture temperature was kept at no more than 45 ℃. After removing the air bubbles from the mixture in a vacuum oven, the mixture was carefully poured onto ultra high molecular weight polyethylene sheet to form a coating of about 3mm thickness.
After the bubbles of the coating are further removed, the coating is polymerized for 8 hours under the radiation of a 525nm light source at room temperature, and then polymerized for 12 hours under the vacuum pumping conditions of 90 ℃, 6 hours and 110 ℃. The polymerized sample piece was peeled from the polyethylene sheet with the reverse side and irradiated with a 525nm light source at room temperature for an additional 8 hours. The sample is cut into pieces with length and width of 6cm and X6 cm for storage.
Example 3
15.0 percent of antibacterial agent No. 3 of antibacterial mother powder, 50 percent of methyl methacrylate and catalyst (ZnTPP/TiO)2BPO 8:2) 2%, the balance being polymethyl methacrylate resin powder.
The mixture was placed in a high speed mixer (equipped with a cooling device). Agitation was started at a low speed (about 50-80RPM) and after three minutes the speed was gradually increased to a high speed (about 400RPM) and agitation was continued for 3 minutes. During which time the mixture temperature was kept at no more than 45 ℃. After removing the air bubbles from the mixture in a vacuum oven, the mixture was carefully poured onto ultra high molecular weight polyethylene sheet to form a coating of about 3mm thickness.
After the bubbles of the coating are further removed, the coating is polymerized for 8 hours under the radiation of a 525nm light source at room temperature, and then polymerized for 12 hours under the vacuum pumping conditions of 90 ℃, 6 hours and 110 ℃. The polymerized sample piece was peeled from the polyethylene sheet with the reverse side and irradiated with a 525nm light source at room temperature for an additional 8 hours. The sample is cut into pieces with length and width of 6cm and X6 cm for storage.
Comparative example 1
5.0 percent of silver ion antibacterial agent, 50 percent of methyl methacrylate and catalyst (ZnTPP/TiO)2BPO 8:2) 2%, the balance being polymethyl methacrylate resin powder.
The mixture was placed in a high speed mixer (equipped with a cooling device). Agitation was started at a low speed (about 50-80RPM) and after three minutes the speed was gradually increased to a high speed (about 400RPM) and agitation was continued for 3 minutes. During which time the mixture temperature was kept at no more than 45 ℃. After removing the air bubbles from the mixture in a vacuum oven, the mixture was carefully poured onto ultra high molecular weight polyethylene sheet to form a coating of about 3mm thickness.
After the bubbles of the coating are further removed, the coating is polymerized for 8 hours under the radiation of a 525nm light source at room temperature, and then polymerized for 12 hours under the vacuum pumping conditions of 90 ℃, 6 hours and 110 ℃. The polymerized sample piece was peeled from the polyethylene sheet with the reverse side and irradiated with a 525nm light source at room temperature for an additional 8 hours. The sample is cut into pieces with length and width of 6cm and X6 cm for storage.
Comparative example 2
5.0 percent of silver ion antibacterial agent, 50 percent of methyl methacrylate and catalyst (ZnTPP/TiO)2BPO 8:2) 2%, the balance being polymethyl methacrylate resin powder.
The mixture was placed in a high speed mixer (equipped with a cooling device). Agitation was started at a low speed (about 50-80RPM) and after three minutes the speed was gradually increased to a high speed (about 400RPM) and agitation was continued for 3 minutes. During which time the mixture temperature was kept at no more than 45 ℃. After removing the air bubbles from the mixture in a vacuum oven, the mixture was carefully poured onto ultra high molecular weight polyethylene sheet to form a coating of about 3mm thickness.
After the bubbles of the coating are further removed, the coating is polymerized for 8 hours under the radiation of a 525nm light source at room temperature, and then polymerized for 12 hours under the vacuum pumping conditions of 90 ℃, 6 hours and 110 ℃. The polymerized sample piece was peeled from the polyethylene sheet with the reverse side and irradiated with a 525nm light source at room temperature for an additional 8 hours. The sample is cut into pieces with length and width of 6cm and X6 cm for storage.
Test example 1
The test pieces obtained in examples 1 to 3 and comparative examples 1 to 2 were subjected to an antibacterial property test.
Specific results are shown in table 1.
TABLE 1 original antimicrobial Activity values of the swatches
Examples 1-3 are significantly superior to comparative examples 1-2 in antibacterial activity, and examples 1-3 all show antibacterial activity values exceeding 0.5, indicating that the present invention has practical antibacterial effects.
Test example 2
The samples obtained in examples 1 to 3 and comparative examples 1 to 2 were subjected to a warm water immersion test to measure the antibacterial activity value after warm water immersion.
The specific results are shown in Table 2.
TABLE 2 antimicrobial Activity values after Warm Water immersion
Experiments prove that the antibacterial activity value of the sample wafer is almost unchanged after the sample wafer is soaked in warm water, and the practical water washing resistance of the sample wafer is shown. The antibacterial function of the sample of the comparative example was greatly reduced to an unusable level. The antibacterial technology can be used as an objective lens outer body applied to an optical fiber endoscope, and can also be used as various other medical communication equipment, even artificial bones. Because of its antibacterial property, it is possible to greatly reduce the quantity of harmful bacteria of implanted or built-in medical equipment and the quantity of bacteria around the artificial limb, thereby protecting users and patients.
Objective antibacterial outer body forming test
The experiment of example 2 is repeated, the endoscope outer body is made by the injection molding method, the endoscope is assembled to be simply assembled and used for verification, the integral endoscope is proved to have the designed function, then the endoscope objective lens outer body is detached, a sufficient number of outer bodies are collected and crushed, and then the test sheet is formed by injection molding, and the antibacterial performance test is carried out.
The specific results are shown in Table 3.
TABLE 3 antimicrobial Activity value of the objective lens outer body reground material prepared in example 2 to prepare a sample
The above-mentioned antibacterial value is similar to the original test antibacterial value of example 2, is not influenced by the processing and forming process, and is greater than the lowest value of actual use effect of 0.5. Therefore, the invention has practical application performance.
While the present invention has been described with reference to several exemplary embodiments, it is understood that the terminology used is intended to be in the nature of words of description and illustration, rather than of limitation. As the present invention may be embodied in several forms without departing from the spirit or essential characteristics thereof, it should also be understood that the above-described embodiments are not limited by any of the details of the foregoing description, but rather should be construed broadly within its spirit and scope as defined in the appended claims, and therefore all changes and modifications that fall within the meets and bounds of the claims, or equivalences of such meets and bounds are therefore intended to be embraced by the appended claims.
Claims (8)
1. A high polymer optical fiber endoscope objective lens outer body for medical communication equipment is characterized in that raw materials of the objective lens outer body comprise 5-20% of antibacterial mother powder by weight.
2. The polymer optical fiber endoscope objective lens outer body for the medical communication equipment as claimed in claim 1, wherein the antibacterial mother powder comprises the following raw materials by weight percent: 1-4% of antibacterial agent No. 3 of antibacterial mother powder, 0.1-1% of lubricant, 0.1-0.5% of coupling agent and the balance polymethyl methacrylate PMMA.
3. The polymer optical fiber endoscope objective lens outer body for medical communication equipment according to claim 2, wherein the coupling agent is prepared by the following method:
(1) mixing gamma-aminopropyltriethoxysilane and cinnamic acid according to a molar ratio (2-5):1, obtaining a mixture, adding ethanol with the mass of 4-6 times of that of the mixture, and stirring for 10-20 minutes at the temperature of 20-30 ℃ at 200 rpm and 100-;
(2) adding 98 mass percent of concentrated sulfuric acid into the mixed solution A, heating to 60-80 ℃, and stirring for 8-12 hours at the speed of 100-;
(3) and (3) concentrating the mixed solution B under reduced pressure at the pressure of 60Pa and the temperature of 40-60 ℃ until crystals are separated out, standing at 10-20 ℃ for 1-3 hours, filtering through a 300-mesh filter cloth, and drying the solid in a vacuum drying oven at 40-60 ℃ until the weight is constant to obtain the coupling agent.
4. The outer body of the high polymer optical fiber endoscope objective lens for medical communication equipment as claimed in claim 1, wherein the antibacterial No. 2 antibacterial agent comprises the following raw materials in parts by weight: 50-80 parts of methyl methacrylate, 150 parts of PEAm powder, 20-50 parts of catechin, 3-6 parts of eucalyptus essential oil and ZnTPP/TiO25-8 parts of composite photocatalyst/functional agent.
5. The polymer optical fiber endoscope objective lens outer body for medical communication equipment as claimed in claim 4, wherein the antimicrobial mother powder No. 3 antimicrobial agent is prepared by the following method:
the mixture of methyl methacrylate, PEAm powder,catechin, Eucalyptus oil, ZnTPP/TiO2Adding the composite material photocatalyst into a reaction kettle, protecting by using nitrogen, and reacting at the temperature of 130 ℃ by using a light source with the wavelength of 525nm for irradiation; after the reaction is finished, flushing the polymer for multiple times by using nitrogen under the conditions of 120 ℃ temperature and intermittent vacuum pumping of the obtained reactant in the same reaction kettle, wherein the volume of the nitrogen is 20 reaction kettles each time; then the obtained reactant is washed by 10 times of deionized water and soaked for ten minutes again, repeated for many times, finally dried in vacuum, and the obtained polymer is ground under the condition of liquid nitrogen to be ground into powder<0.3um diameter powder, stored for use.
6. The polymer optical fiber endoscope objective lens outer body for medical communication equipment as claimed in claim 4, wherein said ZnTPP/TiO is2The preparation method of the nano photocatalyst comprises the following steps:
mixing pyrrole, benzaldehyde and propionic acid, stirring by magnetic force, adding Zn (OAc)2-2H2Continuously stirring O ethanol solution, slowly adding butyl titanate to form dark reddish brown sol, standing until the sol becomes dry gel, vacuum drying, grinding the obtained solid at low temperature, and sintering to obtain ZnTPP/TiO2A composite photocatalyst.
7. The polymer optical fiber endoscope objective lens outer body for medical communication equipment as claimed in claim 6, wherein said ZnTPP/TiO is2The nano photocatalyst comprises the following raw materials in parts by weight: 10-20 parts of pyrrole, 10-20 parts of benzaldehyde, 20-50 parts of propionic acid, Zn (OAc)2-2H22-5 parts of O ethanol solution and 200 parts of butyl titanate 100-; wherein the pH value of the propionic acid is 5.
8. A method for preparing the outer body of the high polymer optical fiber endoscope objective lens for the medical communication equipment according to any one of claims 1 to 7, which comprises adding 5 to 20 weight percent of antibacterial mother powder into the raw material of the outer body of the objective lens, and preparing the outer body of the objective lens according to the prior art.
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103073907A (en) * | 2011-10-26 | 2013-05-01 | 中国石油化工股份有限公司 | Antibacterial thermoplastic plastic composition and preparation method thereof |
| CN105670212A (en) * | 2016-04-14 | 2016-06-15 | 无锡智谷锐拓技术服务有限公司 | Antibacterial plastic |
| CN107841795A (en) * | 2017-09-26 | 2018-03-27 | 浙江玉智德新材料科技有限公司 | A kind of long acting antibiotic polyethylene ES hot blast antibacterial nonwoven cloths and preparation method thereof |
| CN109320889A (en) * | 2018-11-02 | 2019-02-12 | 湖北光合生物科技有限公司 | A kind of polymethyl methacrylate antimicrobial composite material and preparation method thereof |
-
2020
- 2020-09-24 CN CN202011016354.7A patent/CN112126184A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103073907A (en) * | 2011-10-26 | 2013-05-01 | 中国石油化工股份有限公司 | Antibacterial thermoplastic plastic composition and preparation method thereof |
| CN105670212A (en) * | 2016-04-14 | 2016-06-15 | 无锡智谷锐拓技术服务有限公司 | Antibacterial plastic |
| CN107841795A (en) * | 2017-09-26 | 2018-03-27 | 浙江玉智德新材料科技有限公司 | A kind of long acting antibiotic polyethylene ES hot blast antibacterial nonwoven cloths and preparation method thereof |
| CN109320889A (en) * | 2018-11-02 | 2019-02-12 | 湖北光合生物科技有限公司 | A kind of polymethyl methacrylate antimicrobial composite material and preparation method thereof |
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