CN112111397A

CN112111397A - A prevent excursion type priming device for organizational project

Info

Publication number: CN112111397A
Application number: CN202010990749.0A
Authority: CN
Inventors: 齐国友; 于亚美
Original assignee: Individual
Current assignee: Individual
Priority date: 2020-09-19
Filing date: 2020-09-19
Publication date: 2020-12-22

Abstract

The invention discloses an anti-deviation liquid injection device for tissue engineering, which comprises a fixed platform, a culture dish placing frame, a sliding mechanism, a liquid injection mechanism and a protection mechanism, wherein a placing groove is formed in one side of the top of the fixed platform, the culture dish placing frame with a placing cavity formed in the top is fixedly installed on the inner side of the placing groove, and the sliding mechanism is arranged on the other side of the top of the fixed platform. The liquid injection mechanism of the invention realizes the functions of automatically extracting old culture liquid and injecting new culture liquid, and is convenient to take down all the suction heads and the liquid injection heads, thereby being convenient to clean the suction heads and the liquid injection heads; protection machanism's setting has not only realized absorbing the head and has annotated the liquid head and stretch into before the culture dish, fixes the culture dish, has still realized absorbing the head and annotating the liquid head and break away from the culture dish after, carries out the function of fixing to the culture dish, and then when having realized not the tight culture dish of fixed clamp again for when annotating the liquid to the culture dish, guaranteed the function that the culture dish position does not squint.

Description

A prevent excursion type priming device for organizational project

Technical Field

The invention relates to the technical field of tissue engineering, in particular to an anti-migration liquid injection device for tissue engineering.

Background

In the field of tissue engineering, cell culture is generally performed in a culture dish, a culture solution needs to be injected into the culture dish during the cell culture process, the culture solution needed to be used is different at different stages of the culture, and the specific process of injecting the culture solution in the prior art is as follows: the lid of the dish is first removed, the culture solution in the dish is then sucked out by a needle tube, a new solution is then injected into the dish by another needle tube, and finally the lid of the dish is closed.

In the prior art, the culture solution is injected mainly by manual operation, so that the injection efficiency is low, the production cost is high, the accuracy is poor and the labor amount of workers is large in large-scale production.

Disclosure of Invention

In order to solve the above problems, an object of the present invention is to provide an anti-migration injection device for tissue engineering.

The invention realizes the purpose through the following technical scheme:

an anti-deviation type liquid injection device for tissue engineering comprises a fixed platform, a culture dish placing frame, a sliding mechanism, a liquid injection mechanism and a protection mechanism, wherein a placing groove is formed in one side of the top of the fixed platform, the culture dish placing frame with a placing cavity formed in the top is fixedly installed on the inner side of the placing groove, the sliding mechanism is arranged on the other side of the top of the fixed platform, the liquid injection mechanism is arranged on the top of the sliding mechanism, the protection mechanism is arranged on one side, close to the culture dish placing frame, of the sliding mechanism, the protection mechanism is located below the liquid injection mechanism, the liquid injection mechanism comprises a mounting frame, an air cylinder, a fixed frame, a fixed block, an absorption head, a liquid injection head, a first liquid storage tank, a first water pump, a second liquid storage tank and a second water pump, the mounting frame is connected to the top of the sliding mechanism through bolts, the top of the, the output end of the cylinder penetrates through the mounting frame and is provided with the separable fixed frame, the fixed frame is connected with the fixed block through a screw at the inner side, the bottom of the fixed block is connected with the suction head and the liquid injection head through screws, the first liquid storage tank is connected with the top of the fixed platform through screws, the front end of the first liquid storage tank is connected with the first water pump through screws, the liquid outlet end of the first water pump is communicated with the inside of the first liquid storage tank, the liquid inlet end of the first water pump is communicated with the suction head through a water pipe connector and a water pipe, the second liquid storage tank is connected with the top of the fixed platform through screws and is positioned on one side of the first liquid storage tank, the front end of the second liquid storage tank is connected with the second water pump through screws, and the liquid inlet end of the second water pump is communicated with the inside of the second liquid storage, the play liquid end of second water pump pass through water piping connection head and water pipe with annotate first intercommunication of liquid, set up like this and to drive fixed frame through the cylinder and descend, fixed frame drives the fixed block and descends, the fixed block drives and absorbs the head and annotates the liquid head and descend, make and absorb the head and annotate inside the culture dish with annotating the liquid head, then produce the negative pressure through first water pump, make and absorb the head and extract the inside old culture solution of culture dish, and transmit to in the first stock solution case, can also pour the inside new culture solution of second stock solution case into the culture dish through the second water pump, the function of automatic liquid injection has been realized, because separable connection between fixed frame and the cylinder, realized conveniently taking off all absorption heads and annotate the liquid head, and then made things convenient for the washing to absorption head and annotate the liquid head, protection mechanism includes mount, slider, reset spring, clamp plate, the hole of stepping, The fixing frame is connected to the front end of the sliding mechanism through a bolt, a sliding groove is formed in the inner side of the vertical part of the fixing frame, the sliding block is connected to the inner side of the sliding groove in a sliding mode, the bottom of the sliding block is connected with the reset spring through a bolt, one end, far away from the sliding block, of the reset spring is connected to the bottom of the inner side of the sliding groove through a bolt, clamping grooves are formed in the opposite surfaces of the two sliding blocks, the pressing plate is connected to the clamping grooves in a clamping mode, abdicating holes corresponding to the suction head and the liquid injection head are formed in the pressing plate, the top of the pressing plate is connected with the buffer spring through a bolt, the buffer spring can be extruded through the descending of the fixing frame in the mode, the buffer spring drives the pressing plate to descend and is used for the elastic action of the buffer spring, the pressing plate is, when the lifting suction head and the liquid injection head are arranged, due to the action of the buffer spring, the suction head and the liquid injection head are firstly separated from the culture dish, then under the action of the reset spring, the culture dish is kept away from the pressing plate, when the lifting suction head and the liquid injection head are realized, the function of moving the culture dish is prevented, and when the culture dish is not fixedly clamped, the function of not deviating the position of the culture dish is ensured.

Preferably, the outer side of the bottom of the fixed platform is provided with a mounting lug, a mounting hole is formed in the mounting lug, and the whole device can be fixed through the foundation bolt.

Preferably, one side of the placing groove is provided with a clamping assembly for clamping the culture dish placing frame, so that the culture dish placing frame can be clamped and fixed through the clamping assembly.

Preferably, the clamping assembly is mainly connected with the adjusting rod on the inner wall of the placing groove through threads, the rotating disc for driving the adjusting rod to rotate and pressurize the clamping sheets of the culture dish placing rack, so that the adjusting rod can rotate through rotating the rotating disc, the adjusting rod drives the clamping sheets to clamp the culture dish placing rack, and clamping and fixing of the culture dish placing rack are achieved.

Preferably, the sliding mechanism comprises horizontal sliding rails, a transmission screw rod, a moving frame and guide posts, the horizontal sliding rails are connected to two sides of the top of the fixed platform through bolts, one of the horizontal sliding rails is connected with the guide posts through bolts, the other horizontal sliding rail is connected with the transmission screw rod through bearings, one end of the transmission screw rod, far away from the culture dish placing frame, extends out of the horizontal sliding rails and is connected with a driving assembly, two support legs of the moving frame extend into the horizontal sliding rails and are respectively in threaded connection with the transmission screw rod and are in sliding connection with the guide posts, so that the transmission screw rod can be driven to rotate through the driving assembly, the moving frame is driven to move through the rotation of the transmission screw rod, the function of driving the liquid injection mechanism and the protection mechanism to move is realized, and when the culture dish is not injected with liquid, so that the liquid injection mechanism and the protection mechanism are far away from the culture dish, and the culture dish is convenient to observe.

Preferably, the drive assembly mainly by bolted connection be in the driving motor on the fixed station constitutes, driving motor's output with carry out the transmission through belt group or chain group between the drive screw, set up like this and can drive belt group or chain group and rotate, and then realized drive screw's rotation.

Preferably, slide mechanism includes horizontal slide rail, removes frame, guide post, sliding cylinder, horizontal slide rail passes through bolted connection and is in fixed station top both sides, two horizontal slide rail inboard all has through bolted connection the guide post, guide post outside sliding connection has sliding cylinder, just sliding cylinder top has through bolted connection the removal frame sets up like this and can slide in the guide post outside through sliding cylinder, and sliding cylinder drives and removes the removal frame and removes, and then has realized driving the function that annotates liquid mechanism and protection machanism and remove, has realized not annotating the liquid in the culture dish for annotate liquid mechanism and protection machanism and keep away from the culture dish, made things convenient for and observed the culture dish.

Preferably, there is the electro-magnet output bottom of cylinder through bolted connection, there is the iron plate fixed frame top central authorities inboard, and the iron plate top has seted up square recess, and this electro-magnet bottom stretches into in this recess, and adsorbs with this iron plate to be connected, sets up like this and to the absorption of iron plate through the electro-magnet, has not only realized fixed frame fixed connection in the output bottom of cylinder, has still made things convenient for fixed frame to follow because the output bottom of cylinder dismantles, and the setting of square recess is seted up at the iron plate top for fixed frame can not take place to rotate.

Preferably, water piping connection head is water pipe quick-operation joint, sets up like this and makes the water pipe of connecting the absorption head and annotating the liquid head can install fast on first water pump or second water pump to and the quick follow is taken off on first water pump or the second water pump.

Preferably, the main body material of the fixed frame is plastic, so that the weight of the fixed frame is reduced, and the fixed frame is convenient to take.

Has the advantages that:

1. the device can drive the fixed frame to descend through the air cylinder, the fixed frame drives the fixed block to descend, the fixed block drives the suction head and the liquid injection head to descend, the suction head and the liquid injection head extend into a culture dish, negative pressure is generated through the first water pump, the suction head extracts old culture liquid in the culture dish and transmits the old culture liquid to the first liquid storage tank, new culture liquid in the second liquid storage tank can be poured into the culture dish through the second water pump, the function of automatically injecting liquid into a plurality of culture dishes at one time is realized, due to the separable connection between the fixed frame and the air cylinder, all the suction heads and the liquid injection heads can be conveniently taken down, and further the suction heads and the liquid injection heads can be conveniently cleaned;

2. this device can be through fixed frame's decline extrusion buffer spring, buffer spring drives the clamp plate and descends, an elastic force for buffer spring acts on, make the clamp plate press at first in the culture dish top, fix the culture dish, make the absorption head with annotate during the liquid head can be accurate stretches into the culture dish, when promoting the absorption head and annotating the liquid head, because buffer spring's effect, make the absorption head break away from the culture dish with annotating the liquid head at first, then under reset spring's effect, make the culture dish kept away from to the clamp plate, when having realized the promotion absorption head and annotating the liquid head, prevent the function that the culture dish removed, and then when having realized not the fixed clamp culture dish again, when making to annotate the liquid to the culture dish, the function of culture dish position skew has been guaranteed.

Additional features of the invention and advantages thereof will be set forth in the description which follows, and in part will be obvious from the description, or may be learned by practice of the invention.

Drawings

The accompanying drawings, which are included to provide a further understanding of the invention and are incorporated in and constitute a part of this specification, illustrate embodiments of the invention and together with the description serve to explain the principles of the invention and not to limit the invention. In the drawings:

FIG. 1 is a schematic structural diagram of an anti-migration injection device for tissue engineering according to the present invention;

FIG. 2 is a schematic structural diagram of a fixing table of an anti-migration type injection device for tissue engineering according to the present invention;

FIG. 3 is a first structural schematic diagram of an injection mechanism of an anti-migration injection device for tissue engineering according to the present invention;

FIG. 4 is a second structural diagram of the injection mechanism of the anti-migration injection device for tissue engineering according to the present invention;

FIG. 5 is a first structural schematic diagram of a protection mechanism of an anti-migration type injection device for tissue engineering according to the present invention;

FIG. 6 is a second structural diagram of a protection mechanism of an anti-migration type injection device for tissue engineering according to the present invention;

FIG. 7 is a schematic structural diagram of a sliding mechanism of an anti-migration injection device for tissue engineering according to a first embodiment of the present invention;

fig. 8 is a schematic structural diagram of a second embodiment of the sliding mechanism of the anti-migration type injection device for tissue engineering according to the present invention.

The reference numerals are explained below:

1. a fixed table; 2. placing a culture dish rack; 3. a sliding mechanism; 4. a liquid injection mechanism; 5. a protection mechanism; 101. mounting lugs; 102. mounting holes; 103. a placement groove; 104. a clamping assembly; 301. a horizontal slide rail; 302. a drive screw; 303. a movable frame; 304. a guide post; 31. a slide cylinder; 401. a mounting frame; 402. a cylinder; 403. a fixed frame; 404. a fixed block; 405. a suction head; 406. a liquid injection head; 407. a first liquid storage tank; 408. a first water pump; 409. a second liquid storage tank; 410. a second water pump; 501. a fixed mount; 502. a slider; 503. a return spring; 504. pressing a plate; 505. a hole of abdication; 506. a buffer spring.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments.

In the description of the present invention, it is to be understood that the terms "upper", "lower", "front", "rear", "left", "right", "top", "bottom", "inner", "outer", and the like, indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, are merely for convenience in describing the present invention and simplifying the description, and do not indicate or imply that the device or element being referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus, should not be construed as limiting the present invention.

Example 1

As shown in fig. 1-7, an anti-shifting liquid injection device for tissue engineering comprises a fixed platform 1, a culture dish placing rack 2, a sliding mechanism 3, a liquid injection mechanism 4 and a protection mechanism 5, wherein a placing groove 103 is formed on one side of the top of the fixed platform 1, the culture dish placing rack 2 with a placing cavity formed on the top is fixedly installed on the inner side of the placing groove 103, the sliding mechanism 3 is arranged on the other side of the top of the fixed platform 1, the liquid injection mechanism 4 is arranged on the top of the sliding mechanism 3, the protection mechanism 5 is arranged on one side of the sliding mechanism 3 close to the culture dish placing rack 2, the protection mechanism 5 is positioned below the liquid injection mechanism 4, the liquid injection mechanism 4 comprises a mounting frame 401, a cylinder 402, a fixed frame 404, a fixed block 404, a suction head 405, a liquid injection head 406, a first liquid storage tank 407, a first water pump 408, a second liquid storage tank 409 and a second, the top of the front end of the mounting frame 401 is connected with an air cylinder 402 through a bolt, the output end of the air cylinder 402 passes through the mounting frame 401 and is provided with a separable fixed frame 403, the inner side of the fixed frame 403 is connected with a fixed block 404 through a bolt, the bottom of the fixed block 404 is connected with a suction head 405 and a liquid injection head 406 through bolts, a first liquid storage tank 407 is connected with the top of the fixed platform 1 through a bolt, the front end of the first liquid storage tank 407 is connected with a first water pump 408 through a bolt, the liquid outlet end of the first water pump 408 is communicated with the inside of the first liquid storage tank 407, the liquid inlet end of the first water pump 408 is communicated with the suction head 405 through a water pipe connector and a water pipe, a second liquid storage tank 409 is connected with the top of the fixed platform 1 through a bolt and is positioned at one side of the first liquid storage tank 407, the front end of the second liquid storage tank 409 is connected with a second water pump 410 through a bolt, the liquid inlet, the fixed frame 403 can be driven to descend by the air cylinder 402, the fixed frame 403 drives the fixed block 404 to descend, the fixed block 404 drives the suction head 405 and the injection head 406 to descend, the suction head 405 and the injection head 406 extend into the culture dish, negative pressure is generated by the first water pump 408, the suction head 405 sucks old culture solution in the culture dish and transmits the old culture solution to the first liquid storage tank 407, new culture solution in the second liquid storage tank 409 can be poured into the culture dish by the second water pump 410, the automatic liquid injection function is realized, due to the detachable connection between the fixed frame 403 and the air cylinder 402, all the suction head 405 and the injection head 406 can be conveniently taken down, the cleaning of the suction head 405 and the injection head 406 is further convenient, the protection mechanism 5 comprises a fixed frame 501, a sliding block 502, a reset spring 503, a pressing plate 504, a relief hole 505 and a buffer spring 506, the fixing frame 501 is connected to the front end of the sliding mechanism 3 through a bolt, a sliding groove is formed in the inner side of the vertical part of the fixing frame 501, a sliding block 502 is connected to the inner side of the sliding groove in a sliding manner, a return spring 503 is connected to the bottom of the sliding block 502 through a bolt, one end of the return spring 503, which is far away from the sliding block 502, is connected to the bottom of the inner side of the sliding groove through a bolt, clamping grooves are formed in the opposite surfaces of the two sliding blocks 502, a pressing plate 504 is clamped in the clamping grooves, a abdicating hole 505 corresponding to the suction head 405 and the injection head 406 is formed in the pressing plate 504, a buffer spring 506 is connected to the top of the pressing plate 504 through a bolt, the buffer spring 506 can be pressed through the descending of the fixing frame 403, the buffer spring 506 drives the pressing plate 504 to descend for the elastic action of the buffer spring, when the suction head 405 and the injection head 406 are lifted, due to the action of the buffer spring 506, the suction head 405 and the injection head 406 are firstly separated from the culture dish, then the pressing plate 504 is kept away from the culture dish under the action of the reset spring 503, when the suction head 405 and the injection head 406 are lifted, the function of preventing the culture dish from moving is realized, and further when the clamping culture dish is not fixed, the function of ensuring that the position of the culture dish is not deviated is realized when the culture dish is injected with liquid, the mounting lug 101 is arranged on the outer side of the bottom of the fixed platform 1, the mounting hole 102 is formed in the mounting lug 101, the whole device can be fixed through the anchor bolt, the clamping component 104 for clamping the culture dish placing rack 2 is arranged on one side of the placing groove 103, the clamping component 104 can be used for clamping and fixing the culture dish placing rack 2, and the clamping component 104 is mainly formed by an adjusting rod which is in, The rotating disc drives the adjusting rod to rotate, the clamping sheet of the pressurized culture dish placing frame 2 is arranged in such a way that the adjusting rod can rotate by rotating the rotating disc, the adjusting rod drives the clamping sheet to clamp the culture dish placing frame 2, and further clamping and fixing of the culture dish placing frame 2 are realized, the sliding mechanism 3 comprises horizontal sliding rails 301, transmission lead screws 302, a moving frame 303 and guide posts 304, the horizontal sliding rails 301 are connected to two sides of the top of the fixed platform 1 through bolts, the inner side of one horizontal sliding rail 301 is connected with the guide posts 304 through bolts, the inner side of the other horizontal sliding rail 301 is connected with the transmission lead screws 302 through bearings, one end of the transmission lead screws 302, far away from the culture dish placing frame 2, extends out of the horizontal sliding rails 301 and is connected with a driving assembly, two support legs of the moving frame 303 extend into the horizontal sliding rails 301 to be respectively in, the driving assembly can drive the transmission screw 302 to rotate, the rotation of the transmission screw 302 can drive the moving frame 303 to move, so that the function of driving the liquid injection mechanism 4 and the protection mechanism 5 to move is realized, when the culture dish is not injected with liquid, the liquid injection mechanism 4 and the protection mechanism 5 are far away from the culture dish, so that the culture dish can be conveniently observed, the driving assembly mainly comprises a driving motor 305 connected on the fixed platform 1 through bolts, the output end of the driving motor 305 and the transmission screw 302 are driven through a belt set, the driving motor 305 can drive the belt set to rotate through the arrangement, so that the rotation of the transmission screw 302 is realized, the bottom of the output end of the air cylinder 402 is connected with an electromagnet through bolts, an iron block is arranged on the inner side of the center of the top of the fixed frame 403, a square groove is formed in the top of the iron block, and the bottom, and be connected with this iron plate absorption, the setting can be through the absorption of electro-magnet to the iron plate like this, fixed frame 403 fixed connection has not only been realized in the output bottom of cylinder 402, still made things convenient for fixed frame 403 to follow because the output bottom of cylinder 402 is dismantled, the setting of square recess is seted up at the iron plate top, make fixed frame 403 can not take place to rotate, water piping connection head is water pipe quick-operation joint, it makes the water pipe of connecting absorption head 405 and notes liquid head 406 can install fast on first water pump 408 or second water pump 410 to set up like this, and quick taking off from first water pump 408 or second water pump 410, the main part material of fixed frame 403 is plastics, the weight of fixed frame 403 has been alleviateed in the setting like this, the convenience is to fixed frame 403 take.

In the structure, when in use, firstly, new culture solution is filled in the second liquid storage tank 409, then the driving motor 305 is started, the driving motor 305 drives the belt set to rotate, so that the rotation of the transmission lead screw 302 is realized, the rotation of the transmission lead screw 302 enables the movable frame 303 to move, so that the function of driving the liquid injection mechanism 4 and the protection mechanism 5 to move is realized, until the liquid injection mechanism 4 and the protection mechanism 5 reach the foremost end, then the air cylinder 402 is started, the air cylinder 402 drives the fixed frame 403 to descend, the fixed frame 403 drives the fixed block 404 to descend, the fixed block 404 drives the suction head 405 and the liquid injection head 406 to descend, the descending of the fixed frame 403 also extrudes the buffer spring 506, the buffer spring 506 drives the pressing plate 504 to descend for the elastic action of the buffer spring 506, so that the pressing plate 504 is firstly pressed above the culture dish to fix the culture dish, and the suction head 405 and the liquid injection head 406 are ensured to, then the suction head 405 and the injection head 406 extend into the culture dish, negative pressure is generated through the first water pump 408, so that the suction head 405 extracts old culture solution in the culture dish and transmits the old culture solution to the first liquid storage tank 407, new culture solution in the second liquid storage tank 409 can be injected into the culture dish through the second water pump 410, the function of automatic liquid injection is realized, then the suction head 405 and the injection head 406 are lifted, due to the action of the buffer spring 506, the suction head 405 and the injection head 406 are firstly separated from the culture dish, the pressure plate 504 is far away from the culture dish under the action of the reset spring 503, the function of preventing the culture dish from moving when the suction head 405 and the injection head 406 are lifted is realized, the culture dish is not fixedly clamped, the function of ensuring that the position of the culture dish is not deviated when the culture dish is injected, finally the injection motor 305 rotates reversely, so that the sliding mechanism 3 drives the storage rack mechanism 4 and the protection mechanism 5 to be far away from the culture dish 2, the condition of the interior of the culture dish is convenient to observe, and particularly, due to the detachable connection between the fixed frame 403 and the air cylinder 402, all the suction heads 405 and the liquid injection heads 406 can be conveniently taken down, so that the suction heads 405 and the liquid injection heads 406 can be conveniently cleaned.

Example 2

As shown in fig. 8, embodiment 2 differs from embodiment 1 in that: slide mechanism 3 includes horizontal slide rail 301, remove frame 303, guide post 304, sliding cylinder 31, horizontal slide rail 301 passes through bolted connection in 1 top both sides of fixed station, two horizontal slide rail 301 inboards all have guide post 304 through bolted connection, guide post 304 outside sliding connection has sliding cylinder 31, and sliding cylinder 31 top has removal frame 303 through bolted connection, it slides in the guide post 304 outside through sliding cylinder 31 to set up like this, sliding cylinder 31 drives and removes frame 303, and then realized driving the function that annotates liquid mechanism 4 and protection machanism 5 and remove, realized when not annotating liquid to the culture dish, make annotate liquid mechanism 4 and protection machanism 5 and keep away from the culture dish, made things convenient for observing the culture dish.

In the structure, when in use, firstly, new culture solution is filled in the second liquid storage tank 409, then the sliding cylinder 31 is started, the sliding cylinder 31 drives the moving frame 303 to move, so that the function of driving the liquid injection mechanism 4 and the protection mechanism 5 to move is realized, until the liquid injection mechanism 4 and the protection mechanism 5 reach the forefront end, then the cylinder 402 is started, the cylinder 402 drives the fixed frame 403 to descend, the fixed frame 403 drives the fixed block 404 to descend, the fixed block 404 drives the suction head 405 and the liquid injection head 406 to descend, the descending of the fixed frame 403 also presses the buffer spring 506, the buffer spring 506 drives the pressing plate 504 to descend for the elastic action of the buffer spring 506, so that the pressing plate 504 is firstly pressed above the culture dish to fix the culture dish, the suction head 405 and the liquid injection head 406 can accurately extend into the culture dish, and then the suction head 405 and the liquid injection head 406 extend into the culture dish, then, negative pressure is generated through a first water pump 408, so that the suction head 405 extracts old culture solution in the culture dish and transmits the old culture solution to a first liquid storage tank 407, and new culture solution in a second liquid storage tank 409 can be poured into the culture dish through a second water pump 410, thereby realizing the function of automatic liquid injection, then the suction head 405 and the liquid injection head 406 are lifted, due to the action of a buffer spring 506, the suction head 405 and the liquid injection head 406 are firstly separated from the culture dish, and under the action of a return spring 503, the pressing plate 504 is far away from the culture dish, thereby realizing the function of preventing the culture dish from moving when the suction head 405 and the liquid injection head 406 are lifted, further realizing the function of not fixedly clamping the culture dish, ensuring that the position of the culture dish is not deviated when the culture dish is injected with liquid, and finally starting the sliding cylinder 31 again, so that the sliding mechanism 3 drives the liquid injection mechanism 4 and the protection mechanism 5 to be far away from the culture dish 2, the condition of the interior of the culture dish is convenient to observe, and particularly, due to the detachable connection between the fixed frame 403 and the air cylinder 402, all the suction heads 405 and the liquid injection heads 406 can be conveniently taken down, so that the suction heads 405 and the liquid injection heads 406 can be conveniently cleaned.

The foregoing illustrates and describes the principles, general features, and advantages of the present invention. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, which are described in the specification and illustrated only to illustrate the principle of the present invention, but that various changes and modifications may be made therein without departing from the spirit and scope of the present invention, which fall within the scope of the invention as claimed. The scope of the invention is defined by the appended claims and equivalents thereof.

Claims

1. The utility model provides a prevent excursion type priming device for tissue engineering, includes fixed station (1), culture dish rack (2), slide mechanism (3), its characterized in that: still including annotating liquid mechanism (4), protection machanism (5), standing groove (103) have been seted up to fixed station (1) top one side, standing groove (103) inboard fixed mounting has the top to set up and has placed the chamber culture dish rack (2), fixed station (1) top opposite side is provided with slide mechanism (3), slide mechanism (3) top is provided with annotate liquid mechanism (4), slide mechanism (3) are close to one side of culture dish rack (2) is provided with protection machanism (5), just protection machanism (5) are located annotate liquid mechanism (4) below, annotate liquid mechanism (4) including mounting bracket (401), cylinder (402), fixed frame (403), fixed block (404), absorb head (405), annotate liquid head (406), first liquid reserve tank (407), first water pump (408), A second liquid storage tank (409) and a second water pump (410), wherein the mounting frame (401) is connected to the top of the sliding mechanism (3) through bolts, the front end of the mounting frame (401) is connected with the cylinder (402) through bolts, the output end of the cylinder (402) penetrates through the mounting frame (401) and is provided with a separable fixed frame (403), the inner side of the fixed frame (403) is connected with the fixed block (404) through screws, the bottom of the fixed block (404) is connected with the suction head (405) and the liquid injection head (406) through screws, the first liquid storage tank (407) is connected to the top of the fixed table (1) through screws, the front end of the first liquid storage tank (407) is connected with the first water pump (408) through screws, and the liquid outlet end of the first water pump (408) is communicated with the inside of the first liquid storage tank (407), the feed liquor end of first water pump (408) leads to water piping connection head and water pipe with absorb head (405) intercommunication, second liquid reserve tank (409) pass through the screw connection in fixed station (1) top, and be located first liquid reserve tank (407) one side, second liquid reserve tank (409) front end has through screw connection second water pump (410), just the feed liquor end of second water pump (410) with the inside intercommunication of second liquid reserve tank (409), the play liquid end of second water pump (410) leads to water piping connection head and water pipe and annotates liquid head (406) intercommunication, protection machanism (5) include mount (501), slider (502), reset spring (503), clamp plate (504), let a hole (505), buffer spring (506), mount (501) pass through bolted connection in slide machanism (3) front end, the spout has been seted up to the vertical portion inboard of mount (501), the inboard sliding connection of this spout has slider (502), there is reset spring (503) slider (502) bottom through bolted connection, just reset spring (503) are kept away from bolted connection is passed through in the inboard bottom of this spout in the one end of slider (502), two the draw-in groove has all been seted up to the opposite face of slider (502), and the joint has in this draw-in groove clamp plate (504), set up on clamp plate (504) with absorb head (405) and annotate the corresponding hole of stepping down (505) of annotating liquid head (406), there is buffer spring (506) at clamp plate (504) top through bolted connection.

2. The anti-migration liquid injection device for tissue engineering according to claim 1, wherein: the outer side of the bottom of the fixed table (1) is provided with an installation ear (101), and the installation ear (101) is provided with an installation hole (102).

3. The anti-migration liquid injection device for tissue engineering according to claim 1, wherein: and a clamping assembly (104) for clamping the culture dish placing frame (2) is arranged on one side of the placing groove (103).

4. The anti-migration type liquid injection device for tissue engineering according to claim 3, wherein: the clamping assembly (104) mainly comprises an adjusting rod, a rotating disc and a clamping sheet, wherein the adjusting rod is in threaded connection with the inner wall of the placing groove (103), the rotating disc drives the adjusting rod to rotate, and the clamping sheet pressurizes the culture dish placing rack (2).

5. The anti-migration liquid injection device for tissue engineering according to claim 1, wherein: slide mechanism (3) include horizontal slide rail (301), drive screw (302), remove frame (303), guide post (304), horizontal slide rail (301) are in through bolted connection fixed station (1) top both sides, one of them horizontal slide rail (301) inboard has through bolted connection guide post (304), another horizontal slide rail (301) inboard is connected with through the bearing drive screw (302), just drive screw (302) are kept away from the one end of culture dish rack (2) is stretched out horizontal slide rail (301), and is connected with drive assembly, two landing legs that remove frame (303) stretch into horizontal slide rail (301) are inside respectively in drive screw (302) threaded connection, with guide post (304) sliding connection.

6. The anti-migration liquid injection device for tissue engineering according to claim 5, wherein: the driving assembly mainly comprises a driving motor (305) which is connected to the fixed table (1) through a bolt, and the output end of the driving motor (305) and the transmission screw rod (302) are transmitted through a belt set or a chain set.

7. The anti-migration liquid injection device for tissue engineering according to claim 1, wherein: slide mechanism (3) include horizontal slide rail (301), remove frame (303), guide post (304), slip cylinder (31), horizontal slide rail (301) pass through bolted connection and be in fixed station (1) top both sides, two horizontal slide rail (301) inboard all has through bolted connection guide post (304), guide post (304) outside sliding connection has slip cylinder (31), just there is through bolted connection slip cylinder (31) top remove frame (303).

8. The anti-migration liquid injection device for tissue engineering according to claim 1, wherein: the bottom of the output end of the air cylinder (402) is connected with an electromagnet through a bolt, the inner side of the center of the top of the fixed frame (403) is provided with an iron block, the top of the iron block is provided with a square groove, and the bottom of the electromagnet extends into the groove and is connected with the iron block in an adsorption mode.

9. The anti-migration liquid injection device for tissue engineering according to claim 1, wherein: the water pipe connector is a water pipe quick connector.

10. The anti-migration liquid injection device for tissue engineering according to claim 1, wherein: the main material of the fixing frame (403) is plastic.