CN112089952A

CN112089952A - Non-coating antibacterial catheter

Info

Publication number: CN112089952A
Application number: CN202010831878.5A
Authority: CN
Inventors: 毛向明; 韩永俊; 王江河
Original assignee: Zhuhai Tuoai Medical Technology Co ltd
Current assignee: Zhuhai Tuoai Medical Technology Co ltd
Priority date: 2020-08-18
Filing date: 2020-08-18
Publication date: 2020-12-18

Abstract

The invention discloses a non-coating antibacterial catheter, which comprises: the body is provided with a urethral catheterization cavity for urethral catheterization and a urethral catheterization opening communicated with the urethral catheterization cavity; the fixing part is arranged at one end of the body; a urethral catheterization hole is formed in the position, far away from the urethral catheterization opening, of the body, and the urethral catheterization hole can be communicated with the urethral catheterization cavity and the inner wall of the urethra; by applying the non-coating antibacterial catheter, the urethral wall is flushed by the urine discharged by a patient through the drainage hole without antibiotic drugs to assist in antibiosis, and the normal mechanical action of the urethra and the normal defense mechanism of the urinary system are exerted: even if bacteria enter the bladder, 99.9 percent of bacteria and paraglandular secretion can be discharged out of the body by one-time urination. And simultaneously exerts the normal defense mechanism of the urinary system (the defense mechanism is played by antibacterial active substances such as pH urine with acid bias, ammonia, urea, lysozyme, organic matters and the like). Thereby reducing bacterial colonization and greatly reducing the occurrence probability of urethral infection.

Description

Non-coating antibacterial catheter

Technical Field

The invention relates to the field of medical instruments, in particular to a non-coating antibacterial catheter.

Background

Clinically, the catheter is mainly used for removing bladder retention for patients with acute urinary retention, late bladder cancer, urinary incontinence, severe burn and the like, and for indwelling catheterization after surgical operations and the like. The catheter is made of natural rubber, silicon rubber or polyvinyl chloride (PVC), is clinically used for indwelling catheters and temporary catheters, and is quite widely applied. Domestic literature shows that 40% of iatrogenic infections are urinary tract infections and the second most in-home infections; more than 70 percent of the urinary catheters are related, 20 percent of the urinary catheters are caused by operation of urethral instruments and open surgery, urinary tract infection caused by indwelling catheters is very high, and the indwelling catheters mainly provide a continuous passage for bacteria to enter the urethra and the bladder. Urinary tract infections, which are inflammatory reactions of the urothelium to bacterial invasion, are usually accompanied by bacteriuria and purulent urine. Clinically, prevention of urinary tract infection is of great importance.

In the middle of current catheter, because the urethra inner wall is hugged closely to the catheter outer wall, along with the increase of catheter indwelling days, the lateral gland secretion of urethra inner wall can pile up between catheter and urethra, and the internal bacterium of urethra is difficult external along with urine discharge to make the bacterium field planting, lead to the inflammation to take place. In order to prevent urinary tract infection, the clinically-appearing antibacterial coating catheter mainly comprises antibiotic medicines and a nano-silver antibacterial coating, but the clinical effect is not ideal, and on the one hand, the indwelling catheter provides a continuous channel for bacteria to enter the urethra and the bladder. Bacteria are easy to attach and plant on the wall of the urinary catheter and grow into a thin layer of bacteria to be adhered to the pipeline, extracellular matrixes such as polysaccharide-protein compounds secreted by the bacteria embed the bacteria in the thin layer of bacteria, and the like, so that a bacterial biofilm is formed and protected from killing of the antibacterial agent. On the other hand, the antibacterial coating has poor binding force and is easy to dissolve or fall off, and the actual clinical requirement of retaining the continuous long-acting antibacterial agent for 7-14 days is far less met.

In addition, the top end of the traditional catheter is higher than the part of the air bag, which protrudes out of the catheter, so that the patient can easily touch the bladder reflecting area, even if the urine is emptied, the patient still feels the urine distension and the urine frequency, the patient feels pain difficultly, and the trouble of nursing work is increased.

Therefore, how to increase the comfort level and reduce the infection rate by improving the structure and the antibacterial performance of the catheter and standardizing the operation behavior of the sterile catheterization is an important link for preventing and controlling the infection in hospitals.

Disclosure of Invention

The present invention is directed to solving at least one of the problems of the prior art. Therefore, the invention provides a non-coated and non-coated antibacterial catheter, which utilizes the urine drained by a patient to wash the wall of a urethra through a liquid guiding hole by arranging the liquid guiding hole on the catheter, and plays the mechanical role of normal physiology of the urethra: even if bacteria enter the bladder, 99.9 percent of bacteria and paraglandular secretion can be discharged out of the body by one-time urination. Can greatly reduce bacterial colonization and reduce the occurrence probability of urethral infection.

The invention provides a non-coating antibacterial catheter, which comprises: the body is provided with a urethral catheterization cavity for urethral catheterization and a urethral catheterization opening communicated with the urethral catheterization cavity; the fixing part is arranged at one end of the body; the position of keeping away from the urethral catheterization mouth on the body has seted up the catheterization hole, and the catheterization hole can communicate catheterization chamber and urethra inner wall.

Furthermore, a plurality of urethral catheterization holes are formed in the body and are distributed along the axial direction of the body.

Further, a plurality of urethral catheterization holes are distributed along the circumference of the body.

Further, the diameter a of the catheterization hole and the diameter d of the catheterization cavity satisfy 0.01mm < a <0.3 d.

Further, the fixed part is including setting up the sacculus in body one end, this internal have with the pouring into chamber of sacculus intercommunication, pour into chamber and catheterization chamber mutual independence.

Further, the one end that the sacculus was kept away from to the body is provided with the second and connects, and the second connects and catheterization chamber intercommunication.

Furthermore, a notch is arranged at the position of the fixing part on one side of the body, and the urethral catheterization opening is positioned inside the notch.

Further, the fixed part comprises a C-shaped balloon arranged at one end of the body, and the urethral catheterization opening is positioned at the notch of the C-shaped balloon.

Further, a perfusion cavity is formed in the body and communicated with the inner cavity of the C-shaped balloon.

Further, one end of the body, which is far away from the C-shaped balloon, is provided with a second connector, and the second connector is communicated with the perfusion cavity.

When the non-coating antibacterial catheter is used, the catheter can be inserted along the urethra and is fixed by the fixing part, at the moment, urine stored in the bladder inner cavity enters the urethral catheterization cavity through the urethral catheterization opening, and when the urine flows through the urethral catheterization hole, the urine can flow out of the urethral catheterization hole and flow onto the inner wall of the urethra to wash secretions on the inner wall of the urethra, so that the accumulation of the secretions and bacteria on the inner wall of the urethra is effectively improved, the bacterial field planting is reduced, and the prevention and antibacterial treatment effects can be achieved by utilizing the normal physiological mechanical action of the urethra of a human body, and meanwhile, the treatment cost is effectively saved (the price of the coating antibacterial catheter is 4-8 times that of the traditional non-coating catheter). At the same time, since antibiotic is not used for antibacterial coating, drug resistance is not generated, so that the urethra can exert its normal urinary system defense mechanism: including pH urine with partial acid, ammonia, urea, lysozyme, organic matter and other antibacterial active substances.

Additional aspects and advantages of the invention will be set forth in part in the description which follows and, in part, will be obvious from the description, or may be learned by practice of the invention.

Drawings

The above and/or additional aspects and advantages of the present invention will become apparent and readily appreciated from the following description of the embodiments, taken in conjunction with the accompanying drawings of which:

FIG. 1 is a schematic view of a urinary catheter according to an embodiment of the present invention;

FIG. 2 is a cross-sectional view taken along line A-A of FIG. 1;

FIG. 3 is a schematic view of another urinary catheter in an embodiment of the present invention;

FIG. 4 is a cross-sectional view taken along line A-A of FIG. 3;

FIG. 5 is an enlarged view taken at I in FIG. 3;

FIG. 6 is a partial isometric view of another urinary catheter in accordance with an embodiment of the invention;

the above figures contain the following reference numerals.

Detailed Description

Reference will now be made in detail to embodiments of the present invention, examples of which are illustrated in the accompanying drawings, wherein like or similar reference numerals refer to the same or similar elements or elements having the same or similar function throughout. The embodiments described below with reference to the accompanying drawings are illustrative only for the purpose of explaining the present invention, and are not to be construed as limiting the present invention.

In the description of the present invention, it should be understood that the orientation or positional relationship referred to in the description of the orientation, such as the upper, lower, front, rear, left, right, etc., is based on the orientation or positional relationship shown in the drawings, and is only for convenience of description and simplification of description, and does not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and thus, should not be construed as limiting the present invention.

In the description of the present invention, the meaning of a plurality of means is one or more, the meaning of a plurality of means is two or more, and more than, less than, more than, etc. are understood as excluding the present number, and more than, less than, etc. are understood as including the present number. If the first and second are described for the purpose of distinguishing technical features, they are not to be understood as indicating or implying relative importance or implicitly indicating the number of technical features indicated or implicitly indicating the precedence of the technical features indicated.

In the description of the present invention, unless otherwise explicitly limited, terms such as arrangement, installation, connection and the like should be understood in a broad sense, and those skilled in the art can reasonably determine the specific meanings of the above terms in the present invention in combination with the specific contents of the technical solutions.

Referring to fig. 1, 3, 5, the uncoated antimicrobial urinary catheter of the present embodiment comprises: a body 100 having a catheterization cavity 110 for catheterization and a catheterization port 220 communicating with the catheterization cavity 110; a fixing part disposed at one end of the body 100; the position of the main body 100 far away from the urethral catheterization opening 220 is provided with a urethral catheterization hole 140, and the urethral catheterization hole 140 can communicate the urethral catheterization cavity 110 with the inner wall of the urethra.

Use the antibacterial catheter of non-coating of this embodiment, when using, can insert the catheter along the urethra, and lead to the fixed part fixed with the catheter, the urine of storing in the middle of the bladder inner chamber passes through in the middle of catheterization mouth 220 entering catheterization chamber 110 this moment, when urine flows through catheterization hole 140, can flow out and flow in on the urethra inner wall in the middle of the catheterization hole 140, secrete on the urethra inner wall is washed away, effectively improved the accumulational condition of secretion and bacterium on the urethra inner wall, patient's urethra inflammation's possibility has been reduced, the catheter outer wall need not to set up antibacterial coating simultaneously, when guaranteeing antibacterial effect, effectively practiced thrift the cost of coating antibacterial coating.

Wherein, the fixed part can be through multiple mode with the antibiotic catheter of non-coating in the middle of the urethra, for example through setting up structures such as sucking disc or suction nozzle for the catheter can adsorb at urethra inner wall, perhaps through structures such as gasbag or liquid bag, makes the pipe can block in the regional department of urinating of bladder inner wall.

Further, in order to enhance the washing effect on each part of the urethra, the body 100 is provided with a plurality of urethral catheterization holes 140, and the urethral catheterization holes 140 are distributed along the axial direction of the body 100.

On the other hand, in order to make the circumferential washing of the inner wall of the urethra uniform, a plurality of urethral holes 140 are distributed along the circumferential direction of the body 100.

As shown in figures 4 and 5, in order to ensure that urine can seep through the urine guide hole 140 and avoid the phenomenon that the diameter of the urine guide hole 140 is too large to affect the strength of the urinary catheter, the diameter a of the urine guide hole 140 and the diameter d of the urinary catheter cavity 110 satisfy the condition that 0.01mm < a <0.3 d.

As shown in fig. 2, 4 and 6, the fixing part includes a balloon disposed at one end of the body 100, a perfusion cavity 120 communicated with the balloon is disposed in the body 100, and the perfusion cavity 120 and the catheterization cavity 110 are independent from each other; after the ureter inserts among the urethra, can be through filling chamber 120, aerify or towards the liquid to the sacculus for the sacculus can block in the region of urinating of bladder inner wall, when the catheter is demolishd to needs, can discharge the gas or the liquid of filling in the sacculus through filling chamber 120, then take out the catheter can.

In order to facilitate the discharge of urine, the end of the body 100 away from the balloon is provided with a second connector 320, and the second connector 320 is communicated with the urinary catheterization cavity 110.

As shown in fig. 6, the fixing part is provided with a notch at one side of the body 100, the urine guide port 220 is located in the notch, and at this time, because the urine guide port 220 is hidden in the notch, the body 100 does not need to pass through the fixing part and extend into the bladder, thereby effectively reducing the stimulation of the bladder wall reflection area caused by the part of the body 100 extending into the bladder, and reducing the possibility of urine leakage of a patient.

Specifically, the fixing portion includes a C-shaped balloon 200 disposed at one end of the body 100, and the urethral opening 220 is located at a notch of the C-shaped balloon 200.

In order to inflate the C-shaped balloon 200, a second connector 320 is arranged at one end of the body 100 away from the C-shaped balloon 200, and the second connector 320 is communicated with the perfusion cavity 120; when the air pump is used for inflation, the air pump is started by connecting the second connector 320 to the air pump.

The urinary catheter capable of reducing bladder wall irritation of the present embodiment comprises: a body 100 having a catheterization cavity 110 for catheterization; the fixing part is arranged at one end of the body 100, and a notch is arranged at the position, located at one side of the body 100, of the fixing part; the urethral catheterization opening 220 is arranged on the body 100 and communicated with the urethral catheterization cavity 110, and the urethral catheterization opening 220 is positioned inside the gap.

When the catheter capable of reducing the stimulation of the bladder wall is applied, the catheter can be put into the urethra along the urethra, the fixing part is abutted against the inner wall of the bladder, and at the moment, urine in the bladder enters the urethral catheterization cavity 110 through the urethral catheterization opening 220 in the gap; because the urethral catheterization opening 220 is arranged in the gap of the fixing part, the catheter does not need to penetrate through the fixing part and go deep into the bladder, thereby effectively improving the condition that the catheter easily stimulates the reflecting area of the inner wall of the bladder to cause frequent urination of patients and urine leakage.

Further, the fixing portion includes a C-shaped balloon 200 disposed at one end of the body 100, and the urethral opening 220 is located at a gap of the C-shaped balloon 200; at this time, because the urethral orifice 220 is hidden in the gap, the body 100 does not need to pass through the fixing part and extend into the bladder, thereby effectively reducing the stimulation of the bladder wall reflecting area caused by the part of the body 100 extending into the bladder and reducing the possibility of urine leakage of the patient.

In order to inflate the balloon, the body 100 is provided with an infusion cavity 120 therein, and the infusion cavity 120 is communicated with the inner cavity of the C-shaped balloon 200.

Wherein, in order to make the liquid medicine introduced into the bladder better mix with urine, the administration port 210 and the urethral catheterization hole 140 are respectively arranged at two sides of the urethral catheterization hole 140; at this time, it can be ensured that the urine discharged into the urine guide port 220 is the urine mixed with the medicine discharged from the medicine guide port.

As shown in fig. 3, the body 100 is provided with a first connector 310 at a position on one side of the second connector 320, and the first connector 310 is communicated with the urinary catheterization cavity 110.

Wherein, the catheter that can reduce the stimulus of bladder wall of this embodiment still includes: a dosing cavity 130 opened inside the body 100; an administration port 210 which is opened on the body 100 and is used for administering medicine to the bladder cavity; at this time, the drug can be discharged from the administration port 210 into the bladder through the administration lumen 130.

Further, a urethral catheterization hole 140 is formed in the position of the body 100 away from the fixing part, and the urethral catheterization hole 140 is communicated with the urethral catheterization cavity 110; at this time, the medicine is mixed with the urine in the bladder cavity and enters the urethral catheterization cavity 110 along the urethral catheterization opening 220, and when the urine flows through the urethral catheterization hole 140, the urine can directly flow onto the inner wall of the urethra through the urethral hole 140, so that the medicine directly acts on the inner wall of the urethra.

As shown in FIG. 4, the administration lumen 130 and the drainage lumen 110 are independent of each other; at the moment, the situation that the liquid medicine which does not enter the bladder is flushed out by the discharged urine can be avoided, and the waste of the liquid medicine is caused.

The present embodiment also provides a catheter with drug delivery function, including: a body 100 having a catheterization cavity 110 for catheterization and an administration cavity 130 for administration of a drug; a fixing part disposed at one end of the body 100; a urethral catheterization opening 220 which is arranged on the body 100 and communicated with the urethral catheterization cavity 110; an administration port 210 which is opened on the body 100 and is used for administering medicine to the bladder cavity; the urethral catheterization hole 140 is opened at a position of the body 100 far away from the fixing part, and the urethral catheterization hole 140 can communicate the urethral catheterization cavity 110 with the inner wall of the urethra.

Use the catheter that has medicine guide function of this embodiment, after putting the pipe installation in place, can be through dosing chamber 130 and dosing port 210, inject the medicine in the middle of the bladder inner chamber, make medicine and the urine in the middle of the bladder mix, then the urine passes through in the middle of catheterization mouth 220 gets into catheterization chamber 110, when urine flow through catheterization hole 140, can be along on catheterization hole 140 flows out urethra inner wall, the medicine of mixing in the middle of the urine this moment can directly be used in urethra inner wall, the condition that the medicine is difficult to the direct action in urethra inner wall has effectively been improved.

As shown in fig. 3, a third joint 330 is arranged on the body 100, and the third joint 330 is communicated with the medicine guide cavity; at this time, the drug may be injected into the bladder through the third connector 330.

Specifically, a first joint 310 is provided on the body 100 at a position on the side of the third joint 330, and the first joint 310 communicates with the urinary catheterization cavity 110.

As shown in fig. 3 and 5, the body 100 is provided with a plurality of urine guide holes 140, and the plurality of urine guide holes 140 are distributed along the axial direction and/or the axial direction of the body 100; the urine mixed with the medicine can uniformly act on the inner wall of the urethra along the urethral catheterization holes 140 which are axially and/or circumferentially distributed.

In order to avoid the waste of the liquid medicine caused by the urine washing out the liquid medicine which does not enter the bladder, the administration cavity 130 and the catheterization cavity 110 are independent.

As shown in figures 3 to 6, the catheter of the present embodiment can combine the above features to form a multifunctional catheter with antibacterial and drug delivery functions and reduced irritation to bladder wall.

The embodiments of the present invention have been described in detail with reference to the accompanying drawings, but the present invention is not limited to the above embodiments, and various changes can be made within the knowledge of those skilled in the art without departing from the gist of the present invention.

Claims

1. An uncoated antimicrobial urinary catheter, comprising:

a body (100) having a catheterization cavity (110) for catheterization and a catheterization port (220) communicating with the catheterization cavity (110);

a fixing part provided at one end of the body (100);

a urethral catheterization hole (140) is formed in the position, far away from the urethral catheterization opening (220), of the body (100), and the urethral catheterization hole (140) can be communicated with the urethral catheterization cavity (110) and the inner wall of the urethra.

2. The uncoated anti-bacterial catheter according to claim 1, wherein the body (100) is provided with a plurality of the urethral catheterization holes (140), and the plurality of the urethral catheterization holes (140) are distributed along the axial direction of the body (100).

3. The uncoated antimicrobial urinary catheter according to claim 2, wherein a plurality of the urinary guide holes (140) are distributed along the circumference of the body (100).

4. The uncoated anti-bacterial urinary catheter according to claim 3, wherein the diameter a of the urinary drainage hole (140) and the diameter d of the urinary drainage lumen (110) satisfy 0.01mm < a <0.3 d.

5. The uncoated anti-microbial urinary catheter according to claim 1, wherein the fixing part comprises a balloon arranged at one end of the body (100), the body (100) is internally provided with an infusion cavity (120) communicated with the balloon, and the infusion cavity (120) and the urethral catheterization cavity (110) are independent.

6. The uncoated antimicrobial urinary catheter according to claim 5, wherein the end of the body (100) away from the balloon is provided with a second connector (320), the second connector (320) being in communication with the urinary catheter lumen (110).

7. The uncoated anti-microbial urinary catheter according to claim 1, wherein the fixing part is provided with a notch at a position on one side of the body (100), and the urethral opening (220) is positioned inside the notch.

8. The uncoated antimicrobial urinary catheter according to claim 7, wherein the fixing portion comprises a C-shaped balloon (200) arranged at one end of the body (100), the urethral opening (220) being located at a gap of the C-shaped balloon (200).

9. The uncoated anti-bacterial catheter according to claim 8, wherein the body (100) is internally provided with an infusion cavity (120), and the infusion cavity (120) is communicated with the inner cavity of the C-shaped balloon (200).

10. The uncoated anti-bacterial urinary catheter according to claim 9, wherein an end of the body (100) remote from the C-shaped balloon (200) is provided with a second connector (320), the second connector (320) being in communication with the perfusion lumen (120).