CN112089933A - Method for dynamically measuring and calculating respiratory mechanics parameters based on breathing machine - Google Patents
Method for dynamically measuring and calculating respiratory mechanics parameters based on breathing machine Download PDFInfo
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- 230000029058 respiratory gaseous exchange Effects 0.000 title claims abstract description 37
- 230000000241 respiratory effect Effects 0.000 title claims abstract description 30
- 238000000034 method Methods 0.000 title claims abstract description 28
- 238000009423 ventilation Methods 0.000 claims abstract description 27
- 230000003434 inspiratory effect Effects 0.000 claims description 35
- 238000005259 measurement Methods 0.000 claims description 15
- 244000144985 peep Species 0.000 claims description 7
- 238000012545 processing Methods 0.000 abstract description 2
- 210000002345 respiratory system Anatomy 0.000 abstract 2
- 238000010586 diagram Methods 0.000 description 6
- 230000000694 effects Effects 0.000 description 4
- 238000001514 detection method Methods 0.000 description 3
- 210000004072 lung Anatomy 0.000 description 3
- 230000008569 process Effects 0.000 description 3
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 206010061688 Barotrauma Diseases 0.000 description 1
- 208000003417 Central Sleep Apnea Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 230000010355 oscillation Effects 0.000 description 1
- 208000023504 respiratory system disease Diseases 0.000 description 1
- 230000002269 spontaneous effect Effects 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/021—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes operated by electrical means
- A61M16/022—Control means therefor
- A61M16/024—Control means therefor including calculation means, e.g. using a processor
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
Abstract
The invention provides a method for dynamically measuring and calculating respiratory mechanics parameters based on a breathing machine, which relates to the field of measuring and calculating ventilation parameters of the breathing machine and comprises the following steps: acquiring pressure, flow fluctuation and volume data in real time by adopting an airway positive pressure ventilation mode through a respirator; step two: measuring and calculating compliance, inspiration resistance, expiration resistance and inspiration-to-expiration switching flow ratio through pressure, flow fluctuation and volume data; step three: and adjusting ventilation parameters of the breathing machine in real time according to the compliance, the inspiration resistance, the expiration resistance and the inspiration switching flow ratio. The invention measures and calculates the respiratory tract resistance and compliance after acquiring and processing real-time online data to obtain pressure, flow fluctuation and volume data based on the breathing machine in the positive airway pressure mode, does not influence the normal ventilation of a patient, and regulates and outputs the ventilation parameters of the breathing machine in real time according to the measured and calculated respiratory tract resistance and compliance, thereby being convenient for observing the ventilation condition of the patient.
Description
Technical Field
The invention relates to the field of calculation of ventilation parameters of a breathing machine, in particular to a method for dynamically calculating breathing mechanics parameters based on a breathing machine.
Background
The breathing machine is medical equipment with the functions of controlling normal physiological respiration of people, increasing lung ventilation capacity and the like, and is widely applied to clinical application, and the clinical application of the breathing machine improves the treatment condition of respiratory diseases and improves the treatment effect of patients.
In the ventilator ventilation technology, in order to correctly set ventilation parameters (such as breathing air pressure, tidal volume and the like) of a ventilator, a special detection instrument and a special test program are required to be adopted to measure the breathing mechanics parameters of a patient before the ventilator is used, the special detection instrument needs to block spontaneous breathing of the patient when measuring, and needs to be carried out in a state that the patient is calmed and even muscle is relaxed, the ventilation parameters of the ventilator cannot be adjusted in real time in the process that the patient ventilates by using the ventilator, the special detection instrument is not suitable for being carried out when the patient breathes spontaneously or receives auxiliary ventilation, and overhigh or overlow airway pressure and ventilation of the ventilator are easily caused, and side effects such as airway barotrauma of the patient exist.
For solving the parameter setting problem of breathing machine, the patent application number is proposed: 201180024269.8, patent name: systems and methods for estimating upper airway resistance and compliance using induced central apneas by detecting upper airway respiratory resistance and compliance while ensuring that a patient is in a central apneic state; patent application No.: 201480084526, patent name: the method comprises the steps of closing and opening a shutter during expiration in a test, calculating airway resistance and lung compliance through testing pressure and flow, detecting during expiration, and not detecting dynamically; patent application No.: 201610740141.6, patent name: a medical respirator and a method for continuously measuring and calculating respiratory resistance and compliance are disclosed, wherein the method measures and calculates airway resistance and lung compliance by collecting high-frequency oscillation pressure and flow, and a pressure sensor and an airflow sensor are required to be arranged.
Different from the method, the invention provides a method for dynamically measuring and calculating respiratory mechanics parameters based on a breathing machine, in order to measure the airway resistance of a patient in real time and adjust parameters such as the output air pressure of the breathing machine in time in the process of ventilation by adopting the breathing machine.
Disclosure of Invention
In view of the above drawbacks of the prior art, the present invention provides a method for dynamically measuring respiratory mechanics parameters based on a ventilator, which measures respiratory resistance and compliance after acquiring and processing real-time online data in a positive airway pressure mode based on the existing ventilator to obtain pressure, flow fluctuation and volume data, without affecting normal ventilation of a patient; and the breathing machine can adjust the parameters and output of the breathing machine in real time according to the measured respiratory resistance and compliance, so that the ventilation condition of the patient can be observed conveniently.
The invention provides a method for dynamically measuring and calculating respiratory mechanics parameters based on a breathing machine, which comprises the following steps:
the method comprises the following steps: acquiring pressure, flow fluctuation and volume data in real time by adopting an airway positive pressure ventilation mode through a respirator;
step two: compliance C estimation from pressure, flow fluctuation and volumetric datarsAir suction resistance RinspExhalation resistance RexpAnd an inspiratory-to-expiratory flow ratio CC;
step three: according to compliance CrsAir suction resistance RinspExhalation resistance RexpAnd the respiratory switching flow ratio CC, and the ventilation parameter of the breathing machine is adjusted in real time.
Further, the compliance CrsThe measurement formula is as follows:
wherein, VTFor tidal volume, PIP is the maximum inspiratory pressure and PEEP is the positive end expiratory pressure.
Further, the suction resistance RinspThe measurement formula is as follows:
wherein, PPIFPeak inspiratory pressure, PIP maximum inspiratory pressure, PErs-inspFor inspiratory phase to overcome the pressure of elastic resistance, PIF is inspiratory peak Flow, FlowtrigTriggering flow for inspiration.
Further, the pressure P of the suction phase against the elastic resistanceErs-inspThe measurement formula is as follows:
wherein, VTTidal volume, VPIFFor inspiratory peak capacity, CrsIs compliant.
Further, the expiratory resistance RexpThe measurement formula is as follows:
wherein, PPEFFor peak expiratory pressure, PErs-expPEF is the expiratory peak flow for the pressure of the expiratory phase against the elastic resistance.
Further, the pressure P of the expiratory phase against the elastic resistanceErs-expThe measurement formula is as follows:
wherein, VTTidal volume, VPEFTo peak expiratory volume, CrsIs compliant.
Further, the calculation formula of the respiratory switching flow ratio CC is:
wherein, FlowcyFor the flow at the end of inspiration switched to expiration, PIF is the inspiratory peak flow.
Further, the pressure, flow fluctuations, and volume data include tidal volume VTMaximum inspiratory pressure PIP, positive end expiratory pressure PEEP, peak inspiratory flow PIF, peak inspiratory pressure PPIFCapacity V of peak volume of inspirationPIFPeak Expiratory Flow (PEF) and peak expiratory pressure (P)PEFVolume V of peak expiratory volumePEFInspiration trigger FlowtrigAnd Flow rate Flow at the time of switching from inspiration termination to expirationcyThe data are acquired and processed by a respirator in real time.
As described above, the method for dynamically measuring and calculating respiratory mechanics parameters based on the breathing machine of the present invention has the following beneficial effects: the invention is based on that the prior respirator acquires and processes real-time online data under the positive airway pressure mode to obtain pressure, flow fluctuation and volume data and then measures and calculates respiratory resistance and compliance without influencing normal ventilation of a patient; and the breathing machine can adjust the parameters and output of the breathing machine in real time according to the measured respiratory resistance and compliance, so that the ventilation condition of the patient can be observed conveniently.
Drawings
Fig. 1 is a flow-time data waveform diagram/pressure-time data waveform diagram/volume-time data waveform diagram as disclosed in an embodiment of the present invention.
Detailed Description
The embodiments of the present invention are described below with reference to specific embodiments, and other advantages and effects of the present invention will be easily understood by those skilled in the art from the disclosure of the present specification. The invention is capable of other and different embodiments and of being practiced or of being carried out in various ways, and its several details are capable of modification in various respects, all without departing from the spirit and scope of the present invention. It is to be noted that the features in the following embodiments and examples may be combined with each other without conflict.
It should be noted that the drawings provided in the following embodiments are only for illustrating the basic idea of the present invention, and the components related to the present invention are only shown in the drawings rather than drawn according to the number, shape and size of the components in actual implementation, and the type, quantity and proportion of the components in actual implementation may be changed freely, and the layout of the components may be more complicated.
The invention provides a method for dynamically measuring and calculating respiratory mechanics parameters based on a breathing machine, which comprises the following steps:
the method comprises the following steps: acquiring pressure, flow fluctuation and volume data in real time by adopting an airway positive pressure ventilation mode through a respirator;
step two: compliance C estimation from pressure, flow fluctuation and volumetric datarsAir suction resistance RinspExhalation resistance RexpAnd an inspiratory-to-expiratory flow ratio CC;
in particular, the compliance CrsThe measurement formula is as follows:
wherein, VTFor tidal volume, PIP is the maximum inspiratory pressure and PEEP is the positive end expiratory pressure.
In particular, the pressure P of the inspiratory phase against the elastic resistanceErs-inspThe measurement formula is as follows:
wherein, VTTidal volume, VPIFFor inspiratory peak capacity, CrsIs compliant.
Specifically, the suction resistance RinspThe measurement formula is as follows:
wherein, PPIFPeak inspiratory pressure, PIP maximum inspiratory pressure, PErs-inspFor inspiratory phase to overcome the pressure of elastic resistance, PIF is inspiratory peak Flow, FlowtrigTriggering flow for inspiration.
In particular, the pressure P of the expiratory phase against the elastic resistanceErs-expThe measurement formula is as follows:
wherein, VTTidal volume, VPEFTo peak expiratory volume, CrsIs compliant.
In particular, the exhalation resistance RexpThe measurement formula is as follows:
wherein, PPEFFor peak expiratory pressure, PErs-expPEF is the expiratory peak flow for the pressure of the expiratory phase against the elastic resistance.
Specifically, the calculation formula of the respiratory switching flow ratio CC is as follows:
wherein, FlowcyFor the flow at the end of inspiration switched to expiration, PIF is the inspiratory peak flow.
Step three: according to compliance CrsAir suction resistance RinspExhalation resistance RexpAnd the respiratory switching flow ratio CC, and the ventilation parameter of the breathing machine is adjusted in real time.
The pressure, flow fluctuations, and volume data include tidal volume VTMaximum inspiratory pressure PIP, positive end expiratory pressure PEEP, peak inspiratory flow PIF, peak inspiratory pressure PPIFCapacity V of peak volume of inspirationPIFPeak Expiratory Flow (PEF) and peak expiratory pressure (P)PEFVolume V of peak expiratory volumePEFInspiration trigger FlowtrigAnd Flow rate Flow at the time of switching from inspiration termination to expirationcyThe data are acquired and processed by a respirator in real time.
Specifically, as shown in fig. 1, the tidal volume V is a flow-time data waveform diagram/a pressure-time data waveform diagram/a volume-time data waveform diagramTMaximum inspiratory pressure PIP, positive end expiratory pressure PEEP, peak inspiratory flow PIF, peak inspiratory pressure PPIFCapacity V of peak volume of inspirationPIFPeak Expiratory Flow (PEF) and peak expiratory pressure (P)PEFVolume V of peak expiratory volumePEFInspiration trigger FlowtrigAnd Flow rate Flow at the time of switching from inspiration termination to expirationcyCan be obtained from the waveform map.
In conclusion, the respiratory resistance and compliance are measured and calculated after pressure, flow fluctuation and volume data are acquired and processed in real time on line based on the existing breathing machine in the positive airway pressure mode, and normal ventilation of a patient is not affected; the breathing machine adjusts parameters and output of the breathing machine in real time according to the measured respiratory resistance and compliance, so that the ventilation condition of the patient can be observed conveniently; meanwhile, the oscillating pressure is superposed on the pressure level of the positive airway pressure mode, and different amplitudes, frequencies and durations can be set in different breathing intervals, so that the high-frequency oscillating ventilation effect is achieved. Therefore, the invention effectively overcomes various defects in the prior art and has high industrial utilization value.
The foregoing embodiments are merely illustrative of the principles and utilities of the present invention and are not intended to limit the invention. Any person skilled in the art can modify or change the above-mentioned embodiments without departing from the spirit and scope of the present invention. Accordingly, it is intended that all equivalent modifications or changes which can be made by those skilled in the art without departing from the spirit and technical spirit of the present invention be covered by the claims of the present invention.
Claims (8)
1. A method for dynamically measuring and calculating respiratory mechanics parameters based on a breathing machine is characterized by comprising the following steps:
the method comprises the following steps: acquiring pressure, flow fluctuation and volume data in real time by adopting an airway positive pressure ventilation mode through a respirator;
step two: compliance C estimation from pressure, flow fluctuation and volumetric datarsAir suction resistance RinspExhalation resistance RexpAnd an inspiratory-to-expiratory flow ratio CC;
step three: according to compliance CrsAir suction resistance RinspExhalation resistance RexpAnd the respiratory switching flow ratio CC, and the ventilation parameter of the breathing machine is adjusted in real time.
2. The method for dynamic estimation of respiratory mechanics parameters based on ventilator of claim 1, wherein: the compliance CrsThe measurement formula is as follows:
wherein, VTFor tidal volume, PIP is the maximum inspiratory pressure and PEEP is the positive end expiratory pressure.
3. The method for dynamic estimation of respiratory mechanics parameters based on a ventilator according to claim 2, characterized in that: the suction resistance RinspThe measurement formula is as follows:
wherein, PPIFPeak inspiratory pressure, PIP maximum inspiratory pressure, PErs-inspFor inspiratory phase to overcome the pressure of elastic resistance, PIF is inspiratory peak Flow, FlowtrigTriggering flow for inspiration.
4. The method for dynamic estimation of respiratory mechanics parameters based on ventilator of claim 3, wherein: pressure P of said inspiratory phase against elastic resistanceErs-inspThe measurement formula is as follows:
wherein, VTTidal volume, VPIFFor inspiratory peak capacity, CrsIs compliant.
5. The method for dynamic estimation of respiratory mechanics parameters based on ventilator of claim 1, wherein: the exhalation resistance RexpThe measurement formula is as follows:
wherein, PPEFFor peak expiratory pressure, PErs-expPEF is the expiratory peak flow for the pressure of the expiratory phase against the elastic resistance.
6. The method for dynamic estimation of respiratory mechanics parameters based on breathing machines according to claim 5, characterized in that: pressure P of the expiratory phase against elastic resistanceErs-expThe measurement formula is as follows:
wherein, VTTidal volume, VPEFTo peak expiratory volume, CrsIs compliant.
7. The method for dynamic estimation of respiratory mechanics parameters based on ventilator of claim 6, wherein: the calculation formula of the respiratory switching flow ratio CC is as follows:
wherein, FlowcyFor the flow at the end of inspiration switched to expiration, PIF is the inspiratory peak flow.
8. Method for dynamic estimation of respiratory mechanics parameters based on a breathing machine according to claim 4 or 7, characterized in that: pressure, flow fluctuations, and volume data including tidal volume VTMaximum inspiratory pressure PIP, positive end expiratory pressure PEEP, peak inspiratory flow PIF, peak inspiratory pressure PPIFCapacity V of peak volume of inspirationPIFPeak Expiratory Flow (PEF) and peak expiratory pressure (P)PEFVolume V of peak expiratory volumePEFInspiration trigger FlowtrigAnd Flow rate Flow at the time of switching from inspiration termination to expirationcyThe data are acquired and processed by a respirator in real time.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112827030A (en) * | 2021-01-06 | 2021-05-25 | 北京谊安医疗系统股份有限公司 | Expiratory pressure automatic titration method and system based on expiratory airflow limitation index |
| CN114177451A (en) * | 2021-12-29 | 2022-03-15 | 杭州电子科技大学 | Control method of single breathing cycle pressure-volume double control mode of breathing machine |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112827030A (en) * | 2021-01-06 | 2021-05-25 | 北京谊安医疗系统股份有限公司 | Expiratory pressure automatic titration method and system based on expiratory airflow limitation index |
| CN112827030B (en) * | 2021-01-06 | 2023-02-28 | 北京谊安医疗系统股份有限公司 | Expiratory pressure automatic titration method and system based on expiratory airflow limitation index |
| CN114177451A (en) * | 2021-12-29 | 2022-03-15 | 杭州电子科技大学 | Control method of single breathing cycle pressure-volume double control mode of breathing machine |
| CN114177451B (en) * | 2021-12-29 | 2023-11-24 | 杭州电子科技大学 | Control method for single-breathing cycle pressure-capacity double-control mode of breathing machine |
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