CN112089701A - Vitamin E plant soft capsule shell and application thereof - Google Patents
Vitamin E plant soft capsule shell and application thereof Download PDFInfo
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Abstract
The invention discloses a vitamin E plant soft capsule shell and application thereof, wherein the vitamin E plant soft capsule shell is prepared from the following raw materials in parts by weight: 0.5-5 parts of plant gel, 0.01-1 part of coagulant aid, 5-20 parts of film forming agent, 5-10 parts of plasticizer, 0.01-1 part of colorant and 70-100 parts of distilled water. The disintegration time limit of the invention is less than the time required for the disintegration of the gelatin soft capsule. The preparation method disclosed by the invention is reasonable in process design, simple, high in input-output ratio, obvious in economic benefit and high in safety. Compared with the gelatin soft capsule which strictly controls the temperature, the preparation method and the formula of the invention have single requirement on the temperature and higher operability.
Description
Technical Field
The invention belongs to the technical field of edible capsule materials, and particularly relates to a vitamin E plant soft capsule shell and application thereof.
Background
Vitamin e (vitamin e) is a fat-soluble vitamin whose hydrolysate is tocopherol, one of the most important antioxidants. Is dissolved in organic solvents such as fat, ethanol and the like, is insoluble in water, is stable to heat and acid, is unstable to alkali, is sensitive to oxygen and is insensitive to heat. The tocopherol can promote the secretion of sex hormone, so that the vitality and the quantity of sperms of the male are increased; increase female estrogen concentration, improve fertility, prevent abortion, and can be used for preventing and treating male infertility, burn, cold injury, capillary hemorrhage, climacteric syndrome, and skin care. Recently, vitamin E has been found to inhibit the lipid peroxidation in the lens of the eye, dilate peripheral blood vessels, improve blood circulation and prevent the occurrence and development of myopia.
The soft capsule is a packaging mode of capsules, has various shapes, is prepared by processing and processing liquid medicines or sealing the liquid medicines in a soft capsule material, and is widely applied to health care products and pharmaceutical industries. Until now, the variety of the soft capsules reaches more than 3600, the gelatin soft capsule is most widely applied in the current soft capsule market, and the gelatin is deeply favored by the masses due to the unique physicochemical property and the relatively higher nutritional value of the gelatin. However, the unique structural characteristics of the gelatin molecules cause the gelatin to have some defects and shortcomings in application, and the gelatin soft capsules are not suitable for filling contents which easily absorb moisture, efflorescence and react with capsule materials (such as aldehyde-containing substances and the like) because the gelatin soft capsules easily lose moisture to harden, absorb moisture in the air to soften and easily undergo cross-linking and curing reaction when encountering aldehyde-containing substances, and are not easy to break and inconvenient to transport and store, and the gelatin can generate the phenomenon of electrostatic charge accumulation under dry conditions and have certain influence on subsequent processing treatment, so that the gelatin soft capsules are widely used in the pharmaceutical field and have potential safety hazards. Recently, European prions, which are collectively known as synthetic factors such as bovine spongiform encephalopathy (BSE or "mad cow disease") and Jacob-Creutzfeldt syndrome, have been rolled up, and have also given impact on the market of conventional soft gelatin capsules. Furthermore, gelatin soft capsules of animal origin are rejected by many people in the world due to factors in religious beliefs. The outbreak of the 'poison capsule' event in 2012 caused the gelatin soft capsule to frost on snow in development and production, which seriously hindered the development of the soft capsule. Therefore, the development of gelatin substitutes for the preparation of new soft capsules has been highly appreciated by researchers.
Disclosure of Invention
The invention aims to overcome the defects of the prior art and provides a vitamin E plant soft capsule shell.
The invention also aims to provide a vitamin E plant soft capsule.
The invention also aims to provide a preparation method of the vitamin E plant soft capsule.
The technical scheme of the invention is as follows:
a vitamin E plant soft capsule shell is prepared from the following raw material components in parts by weight:
the plant gelling agent is at least one of kappa-carrageenan, sodium alginate and gellan gum, the coagulant aid is at least one of potassium chloride, calcium chloride, potassium citrate and calcium citrate, the film forming agent is at least one of hydroxypropyl methyl cellulose, pullulan, hydroxypropyl starch, carboxymethyl cellulose and sodium carboxymethyl starch, and the plasticizer is at least one of fructose, glycerol, sorbitol and PEG-400.
In a preferred embodiment of the invention, the viscosity of kappa-carrageenan is 250-350 mPa.s (preferably 300 + -20 mPa.s), the viscosity of sodium alginate is 150-250mPa.s (preferably 200 + -20 mPa.s), and the viscosity of gellan gum is preferably 150-250mPa.s (preferably 200 + -20 mPa.s).
In a preferred embodiment of the invention, the colorant is brilliant blue or lemon yellow.
In a preferred embodiment of the invention, the plant gelling agent is kappa-carrageenan, the coagulant aid is potassium citrate or potassium chloride, the film forming agent is composed of pullulan and hydroxypropyl methyl cellulose or hydroxypropyl methyl cellulose and sodium carboxymethyl starch, and the plasticizer is PEG-400 or glycerol.
In a preferred embodiment of the invention, the plant gel is sodium alginate, the coagulant aid is calcium citrate, the film forming agent is pullulan and hydroxypropyl starch, and the plasticizer is sorbitol.
In a preferred embodiment of the invention, the plant gel is gellan gum, the coagulant aid is potassium citrate, the film forming agent is composed of pullulan and sodium carboxymethyl starch or is composed of hydroxypropyl starch and carboxymethyl cellulose, and the plasticizer is glycerol or fructose.
The other technical scheme of the invention is as follows:
a vitamin E plant soft capsule is characterized in that: the capsule skin is the capsule skin of the vitamin E plant soft capsule.
The preparation method of the vitamin E plant soft capsule comprises the following steps:
(1) mixing the plant gel, the coagulant aid, the film forming agent, the plasticizer and distilled water, heating while stirring, heating to 80-90 ℃, stirring for 1.5-2.5 hours to fully mix and swell the plant gel, supplementing distilled water lost by evaporation, vacuumizing, defoaming and standing, naturally cooling to 65-73 ℃, and maintaining the gel at constant temperature for 2-4 hours to obtain a gel solution with the viscosity controlled at 250-350mpa & s;
(2) feeding the glue solution prepared in the step (1) into a glue tank of a capsule machine, and dripping the glue solution and contents into a condensing medium through a concentric shaft multi-layer dripper to obtain wet capsules;
(3) flatly paving the wet gelatin capsules prepared in the step (2) in a tray, turning over once every 0.5h, and shaping for 4-6h to obtain shaped gelatin capsules;
(4) placing the non-woven fabric and the shaped capsule into a roller machine, and absorbing oil on the surface of the shaped capsule by the non-woven fabric to obtain an oil-removing capsule;
(5) and (4) drying the deoiling capsule prepared in the step (4) until the water content is less than 15%, and thus obtaining the vitamin E plant soft capsule.
In a preferred embodiment of the present invention, the condensing medium in step (2) is liquid paraffin, and the parameters of the pill machine are: the diameter of the dripper is 5-6mm, the oil bath temperature is 75-85 ℃, and the temperature of the condensing medium is 20-30 ℃.
In a preferred embodiment of the present invention, the step (4) is: placing the non-woven fabric and the shaped capsule into a roller, setting the circumferential speed of the roller to be 0.4-0.6m/s and the air speed to be 1.5-2.5m/s, and absorbing oil on the surface of the shaped capsule by the non-woven fabric to obtain an oil-removing capsule; the roller machine changes one batch of clean non-woven fabrics every time the roller machine rotates for 8-12min, and each batch of capsules is rubbed with oil for 25-35min, so as to ensure that no bonding occurs between the obtained deoiled capsules.
In a preferred embodiment of the present invention, the step (5) is: and (3) transferring the deoiling capsule prepared in the step (4) to an environment with the temperature of 25-32 ℃ and the relative humidity of 35-45% for drying for at least 12h to ensure that the water content is less than 15%, thus obtaining the vitamin E plant soft capsule.
The invention has the beneficial effects that:
1. the disintegration time limit of the invention (generally about 30 min) is less than the time required for the disintegration of the gelatin soft capsule (the disintegration time limit of the gelatin soft capsule is generally 40-50min, and the disintegration time limit of the gelatin soft capsule is less than 1.0h specified in Chinese pharmacopoeia (2020 edition)).
2. The preparation method disclosed by the invention is reasonable in process design, simple, high in input-output ratio, obvious in economic benefit and high in safety.
3. Compared with the gelatin soft capsule which strictly controls the temperature, the preparation method and the formula of the invention have single requirement on the temperature and higher operability.
Detailed Description
The technical solution of the present invention is further illustrated and described by the following detailed description.
Example 1
(1) Adding 0.15 part by weight of potassium citrate, 2.0 parts by weight of kappa-carrageenan (the viscosity is 300 +/-20 mpa · s), 5 parts by weight of hydroxypropyl methylcellulose, 5 parts by weight of pullulan, 10 parts by weight of PEG-400 and 0.1 part by weight of brilliant blue into 100 parts by weight of distilled water, stirring and heating, heating to 80-90 ℃, stirring for 2 hours to fully mix and swell the mixture, supplementing distilled water lost by evaporation, vacuumizing, removing bubbles, standing for 2 hours, naturally cooling to 70 ℃, and maintaining the glue at constant temperature for 3 hours to obtain a glue solution with the viscosity controlled at 250-350mpa · s;
(2) sending the glue solution prepared in the step (1) into a glue tank of a capsule machine, dripping the glue solution and contents into a condensing medium through a concentric shaft multilayer dripper to obtain wet capsules, wherein the condensing medium is liquid paraffin, and the parameters of the capsule machine are as follows: the diameter of the dripper is 5.5mm, the oil bath temperature is 80 ℃, and the temperature of the condensing medium is 30 ℃;
(3) and (3) flatly paving the wet gelatin capsules prepared in the step (2) in a tray, turning over once every 0.5h, and setting for 5h to obtain the set gelatin capsules.
(4) Placing the non-woven fabric and the shaped capsule into a roller, setting the circumferential speed of the roller to be 0.4-0.6m/s and the air speed to be 1.5-2.5m/s, and absorbing oil on the surface of the shaped capsule by the non-woven fabric to obtain an oil-removing capsule; the roller machine changes a batch of clean non-woven fabrics every 10min of rotation, and each batch of capsules is rubbed with oil for 30min to ensure that no bonding occurs between the obtained deoiled capsules.
(5) And (3) transferring the deoiling capsule prepared in the step (4) to an environment with the temperature of 30 ℃ and the relative humidity of 40% for drying for at least 12 hours to ensure that the water content is less than 15%, thus obtaining the vitamin E plant soft capsule.
(6) And removing the vitamin E plant soft capsules which do not meet the quality requirements, such as eccentricity, solid, bubble, deformation, pill combination, pill breaking and the like in the vitamin E plant soft capsules by using a lamp inspection table, and collecting the qualified vitamin E plant soft capsules for sealing and storing.
(7) The disintegration experiment is carried out according to the requirements of Chinese pharmacopoeia (2020 edition), and the result shows that the disintegration time is less than 1h for 22min, which accords with the requirements of the Chinese pharmacopoeia.
Example 2
(1) Adding 0.2 part by weight of calcium citrate, 3.0 parts by weight of sodium alginate (the viscosity is 200 +/-20 mpa · s), 10 parts by weight of pullulan, 10 parts by weight of hydroxypropyl starch, 10 parts by weight of sorbitol and 0.1 part by weight of lemon yellow into 100 parts by weight of distilled water, stirring and heating, heating to 80-90 ℃, stirring for 2 hours again to fully mix and swell the materials, supplementing the distilled water lost by evaporation, vacuumizing, defoaming and standing for 2 hours, naturally cooling to 70 ℃, and maintaining the glue at constant temperature for 3 hours to obtain a glue solution with the viscosity controlled at 250-350mpa · s;
(2) sending the glue solution prepared in the step (1) into a glue tank of a capsule machine, dripping the glue solution and contents into a condensing medium through a concentric shaft multilayer dripper to obtain wet capsules, wherein the condensing medium is liquid paraffin, and the parameters of the capsule machine are as follows: the diameter of the dripper is 5.5mm, the oil bath temperature is 75 ℃, and the temperature of the condensing medium is 20 ℃;
(3) and (3) flatly paving the wet gelatin capsules prepared in the step (2) in a tray, turning over once every 0.5h, and setting for 5h to obtain the set gelatin capsules.
(4) Placing the non-woven fabric and the shaped capsule into a roller, setting the circumferential speed of the roller to be 0.4-0.6m/s and the air speed to be 1.5-2.5m/s, and absorbing oil on the surface of the shaped capsule by the non-woven fabric to obtain an oil-removing capsule; the roller machine changes a batch of clean non-woven fabrics every 10min of rotation, and each batch of capsules is rubbed with oil for 30min to ensure that no bonding occurs between the obtained deoiled capsules.
(5) And (3) transferring the deoiling capsule prepared in the step (4) to an environment with the temperature of 30 ℃ and the relative humidity of 40% for drying for at least 12 hours to ensure that the water content is less than 15%, thus obtaining the vitamin E plant soft capsule.
(6) And removing the vitamin E plant soft capsules which do not meet the quality requirements, such as eccentricity, solid, bubble, deformation, pill combination, pill breaking and the like in the vitamin E plant soft capsules by using a lamp inspection table, and collecting the qualified vitamin E plant soft capsules for sealing and storing.
(7) The disintegration experiment is carried out according to the requirements of 'Chinese pharmacopoeia' 2015 edition, and the result shows that the disintegration time of the vitamin E plant soft capsule prepared by the embodiment is less than 1h for 27min, and the vitamin E plant soft capsule meets the requirements of the Chinese pharmacopoeia.
Example 3
(1) Adding 0.2 part by weight of calcium citrate, 1.0 part by weight of gellan gum (the viscosity is 200 +/-20 mpa · s), 1.5 parts by weight of kappa-carrageenan (the viscosity is 300 +/-20 mpa · s), 3 parts by weight of sodium carboxymethyl starch, 10 parts by weight of pullulan, 10 parts by weight of glycerol and 0.1 part by weight of tartrazine into 100 parts by weight of distilled water, heating while stirring, heating to 80-90 ℃, stirring for 2 hours again to fully mix and swell the pullulan, supplementing the distilled water lost by evaporation, vacuumizing, defoaming and standing for 2 hours, naturally cooling to 70 ℃, and keeping the temperature for 3 hours to obtain a gelatin curing solution with the viscosity controlled at 250 and 350mpa · s;
(2) sending the glue solution prepared in the step (1) into a glue tank of a capsule machine, dripping the glue solution and contents into a condensing medium through a concentric shaft multilayer dripper to obtain wet capsules, wherein the condensing medium is liquid paraffin, and the parameters of the capsule machine are as follows: the diameter of the dripper is 5.5mm, the oil bath temperature is 85 ℃, and the temperature of a condensing medium is 25 ℃;
(3) and (3) flatly paving the wet gelatin capsules prepared in the step (2) in a tray, turning over once every 0.5h, and setting for 5h to obtain the set gelatin capsules.
(4) Placing the non-woven fabric and the shaped capsule into a roller, setting the circumferential speed of the roller to be 0.4-0.6m/s and the air speed to be 1.5-2.5m/s, and absorbing oil on the surface of the shaped capsule by the non-woven fabric to obtain an oil-removing capsule; the roller machine changes a batch of clean non-woven fabrics every 10min of rotation, and each batch of capsules is rubbed with oil for 30min to ensure that no bonding occurs between the obtained deoiled capsules.
(5) And (3) transferring the deoiling capsule prepared in the step (4) to an environment with the temperature of 30 ℃ and the relative humidity of 40% for drying for at least 12 hours to ensure that the water content is less than 15%, thus obtaining the vitamin E plant soft capsule.
(6) And removing the vitamin E plant soft capsules which do not meet the quality requirements, such as eccentricity, solid, bubble, deformation, pill combination, pill breaking and the like in the vitamin E plant soft capsules by using a lamp inspection table, and collecting the qualified vitamin E plant soft capsules for sealing and storing.
(7) The disintegration experiment is carried out according to the requirements of Chinese pharmacopoeia (2020 edition), and the result shows that the disintegration time of the vitamin E plant soft capsule prepared by the embodiment is 31min less than 1h, and the vitamin E plant soft capsule meets the requirements of the Chinese pharmacopoeia.
Example 4
(1) Adding 0.2 part by weight of potassium citrate, 1.0 part by weight of gellan gum (the viscosity is 200 +/-20 mpa · s), 2.0 part by weight of kappa-carrageenan (the viscosity is 300 +/-20 mpa · s), 3 parts by weight of sodium carboxymethyl starch, 10 parts by weight of hydroxypropyl methyl cellulose, 10 parts by weight of glycerol and 0.1 part by weight of tartrazine into 100 parts by weight of distilled water, heating while stirring, heating to 80-90 ℃, stirring for 2 hours again to fully mix and swell the mixture, supplementing distilled water lost by evaporation, vacuumizing, removing bubbles, standing for 2 hours, naturally cooling to 70 ℃, and maintaining the gel at constant temperature for 3 hours to obtain a gel solution with the viscosity controlled at 250-350mpa · s;
(2) sending the glue solution prepared in the step (1) into a glue tank of a capsule machine, dripping the glue solution and contents into a condensing medium through a concentric shaft multilayer dripper to obtain wet capsules, wherein the condensing medium is liquid paraffin, and the parameters of the capsule machine are as follows: the diameter of the dripper is 5.5mm, the oil bath temperature is 75 ℃, and the temperature of the condensing medium is 20 ℃;
(3) and (3) flatly paving the wet gelatin capsules prepared in the step (2) in a tray, turning over once every 0.5h, and setting for 5h to obtain the set gelatin capsules.
(4) Placing the non-woven fabric and the shaped capsule into a roller, setting the circumferential speed of the roller to be 0.4-0.6m/s and the air speed to be 1.5-2.5m/s, and absorbing oil on the surface of the shaped capsule by the non-woven fabric to obtain an oil-removing capsule; the roller machine changes a batch of clean non-woven fabrics every 10min of rotation, and each batch of capsules is rubbed with oil for 30min to ensure that no bonding occurs between the obtained deoiled capsules.
(5) And (3) transferring the deoiling capsule prepared in the step (4) to an environment with the temperature of 30 ℃ and the relative humidity of 40% for drying for at least 12 hours to ensure that the water content is less than 15%, thus obtaining the vitamin E plant soft capsule.
(6) And removing the vitamin E plant soft capsules which do not meet the quality requirements, such as eccentricity, solid, bubble, deformation, pill combination, pill breaking and the like in the vitamin E plant soft capsules by using a lamp inspection table, and collecting the qualified vitamin E plant soft capsules for sealing and storing.
(7) The disintegration experiment is carried out according to the requirements of Chinese pharmacopoeia (2020 edition), and the result shows that the disintegration time of the vitamin E plant soft capsule prepared by the embodiment is less than 1h for 27min, and the vitamin E plant soft capsule meets the requirements of the Chinese pharmacopoeia.
Example 5
(1) Adding 0.2 part by weight of potassium citrate, 2.0 parts by weight of gellan gum (the viscosity is 200 +/-20 mpa · s), 10 parts by weight of hydroxypropyl starch, 10 parts by weight of carboxymethyl cellulose, 10 parts by weight of fructose and 0.1 part by weight of lemon yellow into 100 parts by weight of distilled water, heating while stirring, heating to 80-90 ℃, stirring for 2 hours to fully mix and swell the mixture, supplementing distilled water lost by evaporation, vacuumizing, defoaming, standing for 2 hours, naturally cooling to 70 ℃, and maintaining the gum at constant temperature for 3 hours to obtain a gum solution with the viscosity controlled at 250 and 350mpa · s;
(2) sending the glue solution prepared in the step (1) into a glue tank of a capsule machine, dripping the glue solution and contents into a condensing medium through a concentric shaft multilayer dripper to obtain wet capsules, wherein the condensing medium is liquid paraffin, and the parameters of the capsule machine are as follows: the diameter of the dripper is 5.5mm, the oil bath temperature is 75 ℃, and the temperature of the condensing medium is 20 ℃;
(3) and (3) flatly paving the wet gelatin capsules prepared in the step (2) in a tray, turning over once every 0.5h, and setting for 5h to obtain the set gelatin capsules.
(4) Placing the non-woven fabric and the shaped capsule into a roller, setting the circumferential speed of the roller to be 0.4-0.6m/s and the air speed to be 1.5-2.5m/s, and absorbing oil on the surface of the shaped capsule by the non-woven fabric to obtain an oil-removing capsule; the roller machine changes a batch of clean non-woven fabrics every 10min of rotation, and each batch of capsules is rubbed with oil for 30min to ensure that no bonding occurs between the obtained deoiled capsules.
(5) And (3) transferring the deoiling capsule prepared in the step (4) to an environment with the temperature of 30 ℃ and the relative humidity of 40% for drying for at least 12 hours to ensure that the water content is less than 15%, thus obtaining the vitamin E plant soft capsule.
(6) And removing the vitamin E plant soft capsules which do not meet the quality requirements, such as eccentricity, solid, bubble, deformation, pill combination, pill breaking and the like in the vitamin E plant soft capsules by using a lamp inspection table, and collecting the qualified vitamin E plant soft capsules for sealing and storing.
(7) The disintegration experiment is carried out according to the requirements of Chinese pharmacopoeia (2020 edition), and the result shows that the disintegration time of the vitamin E plant soft capsule prepared by the embodiment is less than 1h for 27min, and the vitamin E plant soft capsule meets the requirements of the Chinese pharmacopoeia.
The above description is only a preferred embodiment of the present invention, and therefore should not be taken as limiting the scope of the invention, which is defined by the appended claims.
Claims (10)
1. A vitamin E plant soft capsule shell is characterized in that: the composite material is prepared from the following raw materials in parts by weight:
the plant gelling agent is at least one of kappa-carrageenan, sodium alginate and gellan gum, the coagulant aid is at least one of potassium chloride, calcium chloride, potassium citrate and calcium citrate, the film forming agent is at least one of hydroxypropyl methyl cellulose, pullulan, hydroxypropyl starch, carboxymethyl cellulose and sodium carboxymethyl starch, and the plasticizer is at least one of fructose, glycerol, sorbitol and PEG-400.
2. The vitamin E plant soft capsule shell of claim 1, wherein: the colorant is brilliant blue or lemon yellow.
3. The vitamin E plant soft capsule shell of claim 1, wherein: the plant gel is kappa-carrageenan, the coagulant aid is potassium citrate or potassium chloride, the film forming agent is composed of pullulan polysaccharide and hydroxypropyl methyl cellulose or is composed of hydroxypropyl methyl cellulose and sodium carboxymethyl starch, and the plasticizer is PEG-400 or glycerol.
4. The vitamin E plant soft capsule shell of claim 1, wherein: the plant gel is sodium alginate, the coagulant aid is calcium chloride or calcium citrate, the film forming agent is pullulan and hydroxypropyl starch, and the plasticizer is sorbitol.
5. The vitamin E plant soft capsule shell of claim 1, wherein: the plant gel is gellan gum, the coagulant aid is potassium citrate, the film forming agent is composed of pullulan polysaccharide and sodium carboxymethyl starch or is composed of hydroxypropyl starch and carboxymethyl cellulose, and the plasticizer is glycerol or fructose.
6. A vitamin E plant soft capsule is characterized in that: the capsule skin of the vitamin E plant soft capsule as claimed in any one of claims 1 to 5.
7. The method for preparing vitamin E plant soft capsules according to claim 6, which is characterized in that: the method comprises the following steps:
(1) mixing the plant gel, the coagulant aid, the film forming agent, the plasticizer and distilled water, heating while stirring, heating to 80-90 ℃, stirring for 1.5-2.5 hours to fully mix and swell the plant gel, supplementing distilled water lost by evaporation, vacuumizing, defoaming and standing, naturally cooling to 65-73 ℃, and maintaining the gel at constant temperature for 2-4 hours to obtain a gel solution with the viscosity controlled at 250-350mpa & s;
(2) feeding the glue solution prepared in the step (1) into a glue tank of a capsule machine, and dripping the glue solution and contents into a condensing medium through a concentric shaft multi-layer dripper to obtain wet capsules;
(3) flatly paving the wet gelatin capsules prepared in the step (2) in a tray, turning over once every 0.5h, and shaping for 4-6h to obtain shaped gelatin capsules;
(4) placing the non-woven fabric and the shaped capsule into a roller machine, and absorbing oil on the surface of the shaped capsule by the non-woven fabric to obtain an oil-removing capsule;
(5) and (4) drying the deoiling capsule prepared in the step (4) until the water content is less than 15%, and thus obtaining the vitamin E plant soft capsule.
8. The method of claim 7, wherein: the condensing medium in the step (2) is liquid paraffin, and the parameters of the pill machine are as follows: the diameter of the dripper is 5-6mm, the oil bath temperature is 75-85 ℃, and the temperature of the condensing medium is 20-30 ℃.
9. The method of claim 7, wherein: the step (4) is as follows: placing the non-woven fabric and the shaped capsule into a roller, setting the circumferential speed of the roller to be 0.4-0.6m/s and the air speed to be 1.5-2.5m/s, and absorbing oil on the surface of the shaped capsule by the non-woven fabric to obtain an oil-removing capsule; the roller machine changes one batch of clean non-woven fabrics every time the roller machine rotates for 8-12min, and each batch of capsules is rubbed with oil for 25-35min, so as to ensure that no bonding occurs between the obtained deoiled capsules.
10. The method of claim 7, wherein: the step (5) is as follows: and (3) transferring the deoiling capsule prepared in the step (4) to an environment with the temperature of 25-32 ℃ and the relative humidity of 35-45% for drying for at least 12h to ensure that the water content is less than 15%, thus obtaining the vitamin E plant soft capsule.
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