CN112089524B - Drug delivery device for macular degeneration - Google Patents

Drug delivery device for macular degeneration Download PDF

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Publication number
CN112089524B
CN112089524B CN202010969662.5A CN202010969662A CN112089524B CN 112089524 B CN112089524 B CN 112089524B CN 202010969662 A CN202010969662 A CN 202010969662A CN 112089524 B CN112089524 B CN 112089524B
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China
Prior art keywords
plate
eye
hose
liquid medicine
elastic
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CN202010969662.5A
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Chinese (zh)
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CN112089524A (en
Inventor
李崇义
熊艳丽
耿钊
郑鸿
姜姝
张燕
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Chinese Peoples Liberation Army Army Specialized Medical Center
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Chinese Peoples Liberation Army Army Specialized Medical Center
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008Introducing ophthalmic products into the ocular cavity or retaining products therein
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/04Eye-masks ; Devices to be worn on the face, not intended for looking through; Eye-pads for sunbathing
    • A61F9/045Eye-shades or visors; Shields beside, between or below the eyes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00Sprayers or atomisers specially adapted for therapeutic purposes

Abstract

The invention discloses a drug delivery device for macular degeneration, comprising: eye-shade, atomizer, press from both sides pipe mechanism, on-off mechanism, gas cylinder, first hose, liquid medicine bottle and second hose, two press from both sides pipe mechanism and set up eye-shade one side, atomizer sets up in the eye-shade, on-off mechanism sets up the eye-shade with press from both sides in the pipe mechanism, first hose passes one press from both sides pipe mechanism and connects atomizer with the gas cylinder, the second hose passes another press from both sides pipe mechanism and connects atomizer with the liquid medicine bottle. Because atomizer sets up in the eye-shade, and when atomizer atomizes liquid medicine, compressed air in the gas cylinder blows atomizing liquid medicine to patient's eye, reduces atomizing liquid medicine and takes place to bump and at the transportation process, makes the liquid medicine can spray the eye evenly.

Description

Drug delivery device for macular degeneration
Technical Field
The invention relates to the technical field of drug delivery devices, in particular to a drug delivery device for macular degeneration.
Background
Macular degeneration is the leading cause of vision loss in adults over 45 years of age in all countries of the world. The pathogenesis of the macular is not completely clarified, but at present, the macular is known to be related to genetic factors, the aging of pigment epithelium and nerve tissues in the macular area, long-term illumination injury in the macular area, insufficient blood and oxygen supply in the macular area caused by blood circulation disorder, superoxide damage of a yellow spot structure caused by free radicals, and toxic damage of wine, smoke, medicaments and the like. The existing medicine applying device for macular degeneration atomizes liquid medicine through an atomizing device and then sprays the liquid medicine to eyes to achieve a treatment effect. Because the eye-shade is connected with the atomizing device through a telescopic pipe, atomized liquid medicine can seriously collide in the conveying process of the telescopic pipe, thereby being difficult to keep the distribution state of the particle size and being incapable of continuously and uniformly applying the medicine. The atomized liquid medicine is delivered to the eyes, and a certain time is needed for the eyes to absorb the released atomized liquid medicine, but the existing medicine applying device cannot deliver the liquid medicine intermittently according to the needs.
Disclosure of Invention
The present invention is directed to provide a drug delivery device for macular degeneration, which prevents atomized liquid medicine from colliding during delivery and enables the liquid medicine to be uniformly sprayed to the eyes.
In order to achieve the above object, the present invention provides a drug delivery device for macular degeneration, comprising: eye-shade, atomizer, press from both sides pipe mechanism, on-off mechanism, gas cylinder, first hose, liquid medicine bottle and second hose, two press from both sides pipe mechanism and set up eye-shade one side, atomizer sets up in the eye-shade, on-off mechanism sets up the eye-shade with press from both sides in the pipe mechanism, first hose passes one press from both sides pipe mechanism and connects atomizer with the gas cylinder, the second hose passes another press from both sides pipe mechanism and connects atomizer with the liquid medicine bottle.
The pipe clamping mechanism comprises: casing, elastic diaphragm, clamp plate, second spring and fixed plate, the casing sets up eye-shade one side, the fixed plate sets up be close to in the casing eye-shade one end, two elastic diaphragm sets up relatively keep away from in the casing eye-shade one end, clamp plate slidable sets up elastic diaphragm with between the fixed plate and with elastic diaphragm connects, casing, clamp plate and fixed plate all are provided with the hose passageway that supplies the pipeline to pass.
A first spring is arranged between the elastic diaphragms and the shell, so that the two elastic diaphragms are close to each other.
And a magnet is arranged on one side of the pressing plate, which is far away from the elastic diaphragm, and a Hall sensor is arranged on one side of the fixing plate.
The switch mechanism includes: the eye patch comprises a driving plate, a pressing rod, a sleeve, a sliding plate and an inhaul cable, wherein the sleeve is arranged on the eye patch and the pipe clamping mechanism, the sliding plate is slidably arranged in the sleeve, the driving plate is arranged on one side, away from the eye patch, of the pipe clamping mechanism, the pressing rod is connected with the driving plate and the sliding plate, and the inhaul cable penetrates through the fixing plate to be connected with the sliding plate and the pressing plate.
Optionally, the atomizer comprises: the novel piezoelectric ceramic spray nozzle comprises an amplitude transformer, piezoelectric ceramics, an electrode, a rear cover plate, a pretightening nut, a spray nozzle body, a water supply pipe and an air supply pipe, wherein the rear cover plate is arranged at one end of the amplitude transformer, the piezoelectric ceramics are arranged between the rear cover plate and the amplitude transformer, the pretightening nut is connected with the rear cover plate and the amplitude transformer, the electrode is arranged between the piezoelectric ceramics, the spray nozzle body is arranged at one end, away from the amplitude transformer, of the rear cover plate, the water supply pipe penetrates through the pretightening nut to be connected with the spray nozzle body, and the air supply pipe penetrates through the pretightening nut to extend to one side of the spray nozzle body.
Optionally, a liquid collecting box is arranged on one side, away from the switch mechanism, of the eyeshade, and a liquid collecting hole is formed in the eyeshade and is communicated with the eyeshade and the liquid collecting box.
The present invention provides a drug delivery device for macular degeneration comprising: eye-shade, atomizer, press from both sides pipe mechanism, on-off mechanism, gas cylinder, first hose, liquid medicine bottle and second hose, two press from both sides pipe mechanism and set up eye-shade one side, atomizer sets up in the eye-shade, on-off mechanism sets up the eye-shade with press from both sides in the pipe mechanism, first hose passes one press from both sides pipe mechanism and connects atomizer with the gas cylinder, the second hose passes another press from both sides pipe mechanism and connects atomizer with the liquid medicine bottle. Because atomizer sets up in the eye-shade, and when atomizer atomizes liquid medicine, compressed air in the gas cylinder blows atomizing liquid medicine to patient's eye, reduces atomizing liquid medicine and takes place to bump and at the transportation process, makes the liquid medicine can spray the eye uniformly.
Drawings
In order to more clearly illustrate the embodiments of the present invention, the drawings, which are required to be used in the embodiments, will be briefly described below. In all the drawings, the elements or parts are not necessarily drawn to actual scale.
FIG. 1 is a schematic view of a drug delivery device for macular degeneration provided by an embodiment of the present invention;
FIG. 2 is a cross-sectional view of the drug delivery device of FIG. 1 for macular degeneration;
FIG. 3 is a schematic view of an atomizing nozzle provided in accordance with an embodiment of the present invention;
fig. 4 is a schematic view of a vial according to an embodiment of the present invention.
Wherein: 1-eye shield, 101-liquid collecting hole, 2-atomizing nozzle, 3-amplitude transformer, 4-piezoelectric ceramic, 5-electrode, 6-back cover plate, 7-pre-tightening nut, 8-nozzle body, 9-water supply pipe, 10-air supply pipe, 11-pipe clamping mechanism, 12-shell, 13-first spring, 14-elastic diaphragm, 15-pressing plate, 16-second spring, 17-fixing plate, 18-magnet, 19-Hall sensor, 20-liquid collecting box, 21-switch mechanism, 22-driving plate, 23-pressing rod, 24-sleeve, 25-sliding plate, 26-inhaul cable, 27-gas cylinder, 28-first hose, 29-liquid medicine bottle and 30-second hose.
Detailed Description
Embodiments of the present invention will be described in detail below with reference to the accompanying drawings. The following examples are only for illustrating the technical solutions of the present invention more clearly, and therefore are only examples, and the protection scope of the present invention is not limited thereby.
Fig. 1 is a schematic diagram of a drug delivery device for macular degeneration provided in an embodiment of the present invention, fig. 2 is a sectional view of the drug delivery device for macular degeneration in fig. 1, fig. 3 is a schematic diagram of an atomizing spray head provided in an embodiment of the present invention, fig. 4 is a schematic diagram of a drug vial provided in an embodiment of the present invention, and as shown in fig. 1 to fig. 4, the drug delivery device for macular degeneration includes: eye-shade 1, atomizer 2, press from both sides pipe mechanism 11, on-off mechanism 21, gas cylinder 27, first hose 28, liquid medicine bottle 29 and second hose 30, two press from both sides pipe mechanism 11 and set up eye-shade 1 one side, atomizer 2 sets up in the eye-shade 1, on-off mechanism 21 sets up eye-shade 1 with press from both sides on the pipe mechanism 11, first hose 28 passes one press from both sides pipe mechanism 11 and connect atomizer 2 with gas cylinder 27, second hose 30 passes another press from both sides pipe mechanism 11 and connect atomizer 2 with liquid medicine bottle 29. The first hose 28 and the second hose 30 are silicone tubes. The gas cylinder 27 provides compressed air, atomizer 2 is carried through second hose 30 to liquid medicine in the 29 bottles of liquid medicine bottle, and atomizer 2 atomizes liquid medicine, and compressed air blows atomizing liquid medicine to patient's eye, prevents that atomizing liquid medicine from taking place to bump. The atomized liquid medicine is delivered to the eyes, and a certain time is needed for the eyes to absorb the released atomized liquid medicine, but the existing medicine applying device cannot deliver the liquid medicine intermittently according to the needs. The drug delivery device for macular degeneration provided by the invention can intermittently deliver the liquid medicine by clamping the first hose 28 and the second hose 30 through the hose clamping mechanism 11, so that eyes have time to absorb the released atomized liquid medicine.
Referring to fig. 1 to 4, the pipe clamping mechanism 11 includes: casing 12, elastic diaphragm 14, clamp plate 15, second spring 16 and fixed plate 17, casing 12 sets up eye-shade 1 one side, fixed plate 17 sets up be close to in the casing 12 eye-shade 1 one end, two elastic diaphragm 14 sets up relatively keeping away from in the casing 12 eye-shade 1 one end, clamp plate 15 slidable sets up elastic diaphragm 14 with between the fixed plate 17 and with elastic diaphragm 14 is connected, casing 12, clamp plate 15 and fixed plate 17 all are provided with the hose passage that supplies the pipeline to pass. The two elastic membranes 14 are oppositely arranged at two sides of the hose passage, when the pressure plate 15 moves rightwards, the two elastic membranes 14 approach each other and press the hose in the hose passage to interrupt water supply or air supply, and when the pressure plate 15 moves leftwards, the two elastic membranes 14 move away from each other to recover water supply or air supply. A first spring 13 is arranged between the elastic diaphragm 14 and the shell 12, and the first spring 13 extrudes the two elastic diaphragms 14 towards the middle, so that the two elastic diaphragms 14 clamp the hose to interrupt water supply or air supply. The pressing plate 18 is far away from one side of the elastic diaphragm 14 and is provided with a magnet 18, one side of the fixing plate 19 is provided with a Hall sensor 19, when the magnet 18 is close to the Hall sensor 19, water supply and air supply recovery of the hose are realized, and the atomizing nozzle 2 starts to work to atomize the liquid medicine.
Referring to fig. 1 to 4, the switching mechanism 21 includes: the eye mask comprises a driving plate 22, a pressure rod 23, a sleeve 24, a sliding plate 25 and a pull rope 26, wherein the sleeve 24 is arranged on the eye mask 1 and the pipe clamping mechanism 11, the sliding plate 25 is slidably arranged in the sleeve 24, the driving plate 22 is arranged on the side, away from the pipe clamping mechanism 11, of the eye mask 1, the pressure rod 23 is connected with the driving plate 22 and the sliding plate 25, and the pull rope 26 penetrates through the fixing plate 17 to be connected with the sliding plate 25 and the pressure plate 15. When the medicine delivery device for macular degeneration is used, when the eye mask 11 is tightly attached to the eye socket of a patient, the forehead of the patient presses the driving plate 22 rightwards to enable the sliding plate 25 to move rightwards, the sliding plate 25 drives the pressing plate 15 to move leftwards by overcoming the elastic force of the second spring through the inhaul cable 26, the water supply and the air supply of the hose are recovered, and the atomizing nozzle 2 starts to work to atomize the liquid medicine. When the atomized liquid medicine is sprayed to the eyes for a period of time, the patient removes the eyeshade 1 from the eyeshade, the pressing plate 15 moves rightwards under the spring force of the second spring 16 to interrupt the water and air supply of the hose, and the sliding plate 25 moves leftwards under the action of the inhaul cable 26.
Referring to fig. 1 to 4, the atomizer 2 includes: the novel piezoelectric ceramic horn is characterized by comprising an amplitude transformer 3, piezoelectric ceramics 4, an electrode 5, a rear cover plate 6, a pretightening nut 7, a nozzle body 8, a water supply pipe 9 and an air supply pipe 10, wherein the rear cover plate 6 is arranged at one end of the amplitude transformer 3, the piezoelectric ceramics 4 are arranged between the rear cover plate 6 and the amplitude transformer 3, the pretightening nut 7 is connected with the rear cover plate 7 and the amplitude transformer 3, the electrode 5 is arranged between the piezoelectric ceramics 4, the nozzle body 8 is arranged at the position where the amplitude transformer 3 is far away from one end of the rear cover plate 6, the water supply pipe 9 penetrates through the pretightening nut 7 to be connected with the nozzle body 8, and the air supply pipe 10 penetrates through the pretightening nut 7 to extend to one side of the nozzle body 8. The atomizing nozzle 2 further comprises a shell, and the amplitude transformer 3, the piezoelectric ceramic 4, the electrode 5, the rear cover plate 6, the pre-tightening nut 7, the nozzle body 8, the water supply pipe 9 and the air supply pipe 10 are arranged in the shell and are installed in the eye mask 1. The eye patch 1 has two holes, and each hole is provided with an atomizing nozzle 2. The first hose 28 is divided into two branches after passing through the pipe clamping mechanism 11 and respectively connected with the air supply pipes 10 of the two atomizing spray heads 2, and the corresponding second hose 30 is divided into two branches after passing through the pipe clamping mechanism 11 and respectively connected with the air supply pipes 9 of the two atomizing spray heads 2. The liquid collecting box 20 is arranged on one side, away from the switch mechanism 21, of the eye mask 1, and the eye mask 1 is provided with a liquid collecting hole 101 for communicating the eye mask 1 with the liquid collecting box 20. Because the eyeshade 1 is closely attached to the skin around the eyes, in order to balance the air pressure inside the eyeshade 1, a vent hole is formed on the liquid collecting box 20 near the eyeshade 1.
The above examples are only intended to illustrate the technical solution of the present invention, but not to limit it; while the invention has been described in detail and with reference to the foregoing embodiments, it will be understood by those skilled in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some or all of the technical features may be equivalently replaced; such modifications and substitutions do not depart from the spirit and scope of the present invention, and they should be construed as being included in the following claims and description.

Claims (3)

1. A drug delivery device for macular degeneration, comprising: the device comprises an eyeshade, an atomizing nozzle, a pipe clamping mechanism, a switch mechanism, a gas cylinder, a first hose, a liquid medicine bottle and a second hose, wherein the two pipe clamping mechanisms are arranged on one side of the eyeshade;
the pipe clamping mechanism comprises: the elastic mask comprises a shell, elastic membranes, a pressing plate, a second spring and a fixing plate, wherein the shell is arranged on one side of the eye mask, the fixing plate is arranged in the shell and close to one end of the eye mask, the two elastic membranes are oppositely arranged in the shell and far away from one end of the eye mask, the pressing plate is slidably arranged between the elastic membranes and the fixing plate and is connected with the elastic membranes, and the shell, the pressing plate and the fixing plate are all provided with hose passages for pipelines to pass through;
a first spring is arranged between the elastic diaphragms and the shell, so that the two elastic diaphragms are close to each other;
a magnet is arranged on one side of the pressing plate, which is far away from the elastic diaphragm, and a Hall sensor is arranged on one side of the fixing plate;
the switch mechanism includes: the eye patch comprises a driving plate, a pressing rod, a sleeve, a sliding plate and an inhaul cable, wherein the sleeve is arranged on the eye patch and the pipe clamping mechanism, the sliding plate is slidably arranged in the sleeve, the driving plate is arranged on one side, away from the eye patch, of the pipe clamping mechanism, the pressing rod is connected with the driving plate and the sliding plate, and the inhaul cable penetrates through the fixing plate to be connected with the sliding plate and the pressing plate.
2. The drug delivery device for macular degeneration of claim 1, wherein the nebulizing spray head comprises: the back cover plate is arranged at one end of the amplitude transformer, the piezoelectric ceramics are arranged between the back cover plate and the amplitude transformer, the pretightening nut is connected with the back cover plate and the amplitude transformer, the electrode is arranged between the piezoelectric ceramics, the spray head body is arranged between the amplitude transformer and far away from the amplitude transformer, one end of the back cover plate is arranged at one end of the spray head body, the water supply pipe penetrates through the pretightening nut to be connected with the spray head body, and the air supply pipe penetrates through the pretightening nut to extend to one side of the spray head body.
3. The drug delivery device for macular degeneration of claim 1, wherein a liquid trap is provided on a side of the eye mask away from the switch mechanism, and a liquid trap hole is provided on the eye mask to communicate the eye mask and the liquid trap.
CN202010969662.5A 2020-09-15 2020-09-15 Drug delivery device for macular degeneration Active CN112089524B (en)

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CN112089524B true CN112089524B (en) 2022-05-31

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