CN112043375A - Radio frequency microneedle array control method and device and radio frequency microneedle therapeutic apparatus - Google Patents

Radio frequency microneedle array control method and device and radio frequency microneedle therapeutic apparatus Download PDF

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CN112043375A
CN112043375A CN202011069549.8A CN202011069549A CN112043375A CN 112043375 A CN112043375 A CN 112043375A CN 202011069549 A CN202011069549 A CN 202011069549A CN 112043375 A CN112043375 A CN 112043375A
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coordinates
target
microneedle
radio frequency
electrodes
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CN112043375B (en
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雷晓兵
梁永生
李兴里
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Shenzhen Peninsula Medical Group Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14Probes or electrodes therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636Sensing and controlling the application of energy
    • A61B2018/00696Controlled or regulated parameters
    • A61B2018/00702Power or energy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14Probes or electrodes therefor
    • A61B2018/1405Electrodes having a specific shape
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023Drug applicators using microneedles

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Abstract

The invention provides a radio frequency microneedle array control method, a radio frequency microneedle array control device and a radio frequency microneedle therapeutic apparatus, wherein the control method comprises the following steps: obtaining coordinates corresponding to a plurality of microneedle electrodes; determining at least one set of target coordinates from the coordinates of the plurality of microneedle electrodes, wherein each set of target coordinates comprises two target coordinates; sending a first control signal to a switch switching circuit to control the switch switching circuit to connect the target microneedle electrodes corresponding to at least one group of target coordinates with a power supply within a first preset time period, and controlling the switch switching circuit to supply a first electric polarity to one of the target microneedle electrodes corresponding to each group of target coordinates and a second electric polarity to the other target microneedle electrode; returning to the step of determining at least one set of target coordinates from the coordinates corresponding to the plurality of microneedle electrodes. The radio frequency therapeutic apparatus adopting the method has a plurality of transformed energy output points in the radio frequency microneedle therapy process, which is beneficial to more uniform output.

Description

Radio frequency microneedle array control method and device and radio frequency microneedle therapeutic apparatus
Technical Field
The invention relates to the technical field of medical instruments, in particular to a radio frequency microneedle array control method and device and a radio frequency microneedle therapeutic apparatus.
Background
The radio frequency micro-needle therapy is a micro-invasive radio frequency dot matrix technology, which utilizes a tiny micro-needle to accurately apply Radio Frequency (RF) energy to target tissues with different depths, can be used for facial rejuvenation application such as skin tightening and scar removal, and can also be used for acne treatment and axillary hyperhidrosis treatment.
However, in the current micro-needle lattice radio frequency treatment process, there are many problems, for example, the micro-needle electrodes are all designed and fixed as a positive electrode and a negative electrode, that is, the same micro-needle electrode is always used as the positive electrode or the negative electrode in the application process, which causes uneven energy in the treatment process and easily affects the treatment effect and the experience effect.
Disclosure of Invention
The invention mainly aims to provide a radio frequency microneedle array control method and device and a radio frequency microneedle therapeutic apparatus, and aims to solve the technical problem of uneven energy output of a radio frequency microneedle array in the prior art.
In order to achieve the above object, in a first aspect, the present invention provides a radio frequency microneedle array control method, which is applied to a radio frequency microneedle therapeutic apparatus, and the radio frequency microneedle therapeutic apparatus includes: a power supply;
the input end of the switch switching circuit is connected with a power supply; and
a microneedle array comprising a plurality of microneedle electrodes of switchable electrical polarity, wherein each microneedle electrode has a corresponding coordinate, and the microneedle electrodes are electrically connected with an output terminal of the switching circuit;
the method comprises the following steps:
obtaining coordinates corresponding to a plurality of microneedle electrodes;
determining at least one set of target coordinates from the coordinates corresponding to the plurality of microneedle electrodes, wherein each set of target coordinates comprises two target coordinates;
controlling the switch switching circuit to connect the target microneedle electrodes corresponding to the at least one group of target coordinates with a power supply within a first preset time period, and controlling the switch switching circuit to supply a first electric polarity to the target microneedle electrode corresponding to any one target coordinate of each group of target coordinates and a second electric polarity to the target microneedle electrode corresponding to the other target coordinate of each group of target coordinates, wherein the polarities of the first electric polarity and the second electric polarity are opposite;
returning to the step of determining at least one set of target coordinates from the coordinates corresponding to the plurality of microneedle electrodes.
Optionally, after the step of determining at least one set of target coordinates from the coordinates corresponding to the plurality of microneedle electrodes, the method further comprises:
recording the at least one set of target coordinates.
Optionally, before the step of determining at least one set of target coordinates from the coordinates corresponding to the plurality of microneedle electrodes, the method further comprises:
acquiring all historical target coordinates recorded currently;
removing the currently recorded historical target coordinates from the coordinates corresponding to the plurality of microneedle electrodes to obtain remaining effective coordinates;
the step of determining at least one set of target coordinates from the coordinates corresponding to the plurality of microneedle electrodes comprises:
at least one set of target coordinates is determined from the remaining valid coordinates.
Optionally, before the step of determining at least one set of target coordinates from the remaining valid coordinates, the method further includes:
acquiring peripheral coordinates of all historical target coordinates;
removing the peripheral coordinates from the residual effective coordinates to obtain residual optional coordinates;
the step of determining at least one set of target coordinates from the coordinates corresponding to the plurality of microneedle electrodes comprises:
at least one set of target coordinates is determined from the remaining selectable coordinates.
Optionally, after the step of obtaining the peripheral coordinates of all the historical target coordinates, the method further includes:
and removing the peripheral coordinates of which the recording time length is greater than or equal to a second preset time length from all the peripheral coordinates.
Optionally, the step of determining at least one set of target coordinates from the coordinates corresponding to the plurality of microneedle electrodes comprises:
determining at least one set of target coordinates from the coordinates corresponding to the microneedle electrodes according to a preset target microneedle electrode sequence.
Optionally, the first control signal is further used to control the switching circuit to interchange the electric polarities of the two target microneedle electrodes corresponding to each set of target coordinates at least once.
Optionally, a distance between two target coordinates in each set of target coordinates is less than or equal to a first preset distance.
Optionally, a distance between any one of the target coordinates in any one of the sets of target coordinates and any one of the target coordinates in the other sets of target coordinates is greater than or equal to a second preset distance, where the second preset distance is greater than the first preset distance.
In a second aspect, the present embodiment also provides a radio frequency microneedle array control apparatus, including:
the coordinate acquisition module is used for acquiring coordinates corresponding to the microneedle electrodes;
a coordinate determination module for determining at least one set of target coordinates from the coordinates of the plurality of microneedle electrodes, wherein each set of target coordinates comprises two target coordinates;
and the signal sending module is used for controlling the switch switching circuit to connect the target microneedle electrodes corresponding to the at least one group of target coordinates with a power supply within a first preset time period, and controlling the switch switching circuit to supply a first electric polarity for the target microneedle electrodes corresponding to any one target coordinate of each group of target coordinates and supply a second electric polarity for the target microneedle electrodes corresponding to another target coordinate of each group of target coordinates, wherein the polarities of the first electric polarity and the second electric polarity are opposite.
In a third aspect, the present invention further provides a radio frequency microneedle therapeutic apparatus, comprising:
a power supply;
the input end of the switch switching circuit is connected with a power supply;
a microneedle array comprising a plurality of microneedle electrodes of switchable electrical polarity, wherein each microneedle electrode has a corresponding coordinate, and the microneedle electrodes are electrically connected with an output terminal of the switching circuit; and
at least one processor, a memory, and a radio frequency microneedle array control program stored on the memory and executable on the processor, the radio frequency microneedle array control program, when executed by the processor, implementing steps of a radio frequency microneedle array control method.
According to the technical scheme, all the microneedle electrodes in the microneedle array are represented by coordinates in the treatment process, and then at least one group of target coordinates are determined from the coordinates of all the microneedle electrodes, wherein each group of target coordinates comprises two target coordinates; and control switch change over circuit will in the microneedle array with the corresponding microneedle electrode of target coordinate with power supply connects and lasts for first predetermined duration, and with the electric polarity of two microneedle electrodes that every group target coordinate corresponds is opposite, thereby make the radio frequency microneedle treatment in-process have the energy output point of a plurality of transformations, do benefit to the more even output of the energy of radio frequency microneedle therapeutic instrument, thereby improve treatment, and still avoid appearing in the treatment process, certain part organizes the phenomenon that receives energy output and overheat for a long time and takes place, improves the security of treatment.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to the structures shown in the drawings without creative efforts.
Fig. 1 is a schematic structural diagram of a radio frequency microneedle therapy apparatus in a hardware operating environment according to an embodiment of the present invention;
fig. 2 is a schematic flow chart illustrating a radio frequency microneedle array control method according to a first embodiment of the present invention;
fig. 3 is a schematic coordinate diagram of a microneedle array according to an embodiment of the radio frequency microneedle therapy apparatus of the present invention;
fig. 4 is a schematic flow chart illustrating a radio frequency microneedle array control method according to a second embodiment of the present invention;
fig. 5 is a schematic flow chart illustrating a radio frequency microneedle array control method according to a third embodiment of the present invention;
fig. 6 is a schematic diagram of a preset target microneedle electrode track according to an embodiment of the radio frequency microneedle array control method of the present invention;
fig. 7 is a block diagram illustrating a first embodiment of the rf microneedle array control apparatus according to the present invention.
The implementation, functional features and advantages of the objects of the present invention will be further explained with reference to the accompanying drawings.
Detailed Description
It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.
The radio frequency microneedle therapeutic apparatus includes a power supply 100, a microneedle array 200, a switch switching circuit 300, and a controller 400.
The output frequency of the power supply 100 may be 0.3MHz-100MHz, and the power supply 100 may be a continuous output power supply or a pulse output power supply or a continuous and pulse output power supply. The power supply 100 may include only one, that is, a single power supply 100 supplies power to all the microneedle arrays 200. Alternatively, the power supply 100 may include a plurality of power supplies 100, and the plurality of power supplies 100 are connected to the switch switching circuit 300, respectively. Any microneedle electrode in the microneedle array can be powered by any power supply 100 through the switching circuit. Alternatively, each row of microneedle electrodes in the microneedle array 200 is powered by one power supply 100. In order to enable energy output among the multiple groups of target microneedle electrodes to be more consistent, in some embodiments, the microneedle array simultaneously has multiple groups of target microneedle electrodes corresponding to target coordinates, and at the moment, each group of target microneedle electrodes are powered by different independent power supplies 100.
The microneedle array 200 includes a PCB and a plurality of microneedle electrodes disposed on the PCB, and the microneedle electrodes are arranged in an array, for example, in a 7 × 7 array. The microneedle electrodes on the microneedle array 200 can be set as positive electrodes or negative electrodes as required, and the electric polarity of each microneedle electrode can be switched to alternately serve as the positive and negative electrodes in different operation periods. Specifically, the microneedle electrodes can be connected to different ports of the power supply according to the switching circuit.
The input end of the switch switching circuit 300 is connected to the power supply 100, and the output end of the switch switching circuit 300 is electrically connected to the microneedle array 200 through a PCB.
The controller 400 is connected to the switching circuit 300 to control the connection between each microneedle electrode in the microneedle array 200 and the power supply 100. The controller comprises at least one processor 401, a memory 402 and a radio frequency micro-needle array control program stored on the memory 402 and capable of running on the processor 401, wherein the radio frequency micro-needle array control program is configured to realize the steps of the radio frequency micro-needle array control method. In some embodiments, the processor 401, memory 402 are integrated on the same chip or circuit board; in some other embodiments, either or both of processor 401 and memory 402 may be implemented on separate chips or circuit boards. That is, the controller 400 may be a microprocessor such as a single chip, a DSP, an FPGA, or the like, and in some embodiments, may also be implemented by using a chip dedicated to the radio frequency microneedle therapy apparatus, which is not limited in this embodiment.
It will be appreciated by those skilled in the art that the arrangement shown in figure 1 does not constitute a limitation of the rf treatment apparatus and may include more or less components than those shown, or some components may be combined, or a different arrangement of components.
An embodiment of the present invention provides a radio frequency microneedle array control method, and referring to fig. 2, fig. 2 is a schematic flow chart of a first embodiment of the radio frequency microneedle array control method according to the present invention.
In this embodiment, the radio frequency microneedle array control method includes the following steps:
step S100, obtaining coordinates corresponding to the plurality of microneedle electrodes.
Specifically, in this step, the microneedle array pattern is distributed in an array, for example, a 7 × 7 array, on the PCB or the mounting substrate. And the relative position of each microneedle electrode in the microneedle array relative to other microneedle arrays in the microneedle array is unchanged on the installation plane of the microneedle array, so a plane coordinate system can be introduced to represent the position of each microneedle electrode in the microneedle array.
Referring to fig. 3, for a 7 × 7 microneedle array, the microneedles at the lower left corner in the microneedle array can be used as an origin, the rows of the microneedle array are horizontal axes in a planar coordinate system, the columns of the microneedle array are vertical axes in the planar coordinate system, and the spacing between adjacent microneedle electrodes is 1, so the microneedle electrodes in the microneedle array can be represented as: (0,0), (0,1), … …, (0,7), (1,0), (1,1) … … (7, 7).
Therefore, the coordinates corresponding to all the microneedle electrodes can be stored in the controller 400, and when the embodiment of the method is executed, the coordinates stored in the controller 400 are called, that is, the coordinates corresponding to a plurality of the microneedle electrodes are obtained.
In addition, the coordinates of all the microneedle electrodes may be acquired in this step, and the coordinates of a part of the microneedle electrodes may also be acquired. It is easy to understand that due to different treatment positions, there may be some microneedle electrodes that are not inserted into the tissue to be treated, i.e. only some microneedle electrodes in the rf therapy apparatus need to output rf energy. Only the coordinates of the microneedle electrode that is inserted into the tissue and needs to output the radio frequency energy need to be acquired in this step.
It should be noted that, for the part of the microneedle electrodes, whether the microneedle electrodes need to output radio frequency energy can be judged by detecting the impedance of each microneedle electrode.
Step S200, determining at least one set of target coordinates from the coordinates corresponding to the microneedle electrodes, wherein each set of target coordinates comprises two target coordinates.
The target coordinates are coordinates of the microneedle electrodes which need to output radio frequency energy in the subsequent steps. This step is used to select part of the target coordinates from the plurality of microneedle electrodes, which may be random or regular. The present embodiment does not limit this. In addition, the number of target coordinates may be one set or may be a plurality of sets. Optionally, the target coordinates are a set. Each set of target coordinates includes two target coordinates. Namely, step S200 is: a set of target coordinates is determined from the coordinates corresponding to the plurality of microneedle electrodes.
For example, during a treatment session, all microneedle electrodes in a 7 x 7 microneedle array are inserted into the tissue and need to deliver rf energy. An operation of determining target coordinates is performed, and a set of target coordinates is randomly determined from 49 coordinates (0,0) to (7, 7): (3,4) and (3, 5).
Step S300, controlling the switch switching circuit to connect the target microneedle electrodes corresponding to the at least one group of target coordinates with a power supply within a first preset time period, and controlling the switch switching circuit to supply a first electric polarity to the target microneedle electrodes corresponding to any one target coordinate of each group of target coordinates and to supply a second electric polarity to the target microneedle electrodes corresponding to the other target coordinate of each group of target coordinates, wherein the polarities of the first electric polarity and the second electric polarity are opposite.
Specifically, the switching circuit 300 connects the positive electrode and the negative electrode of the power supply 100 to all the targeted microneedle electrodes on the microneedle array based on the control signal of the controller 400, and the microneedle electrodes except the targeted microneedle electrodes in the microneedle array 200 are not connected to the power supply 100, that is, are in an inactive state. And the power supply 100 provides either positive or negative electrical polarity for each set of 2 targeted microneedle electrodes and opposite negative or positive electrical polarity for the other. That is, one of each set of 2 targeted microneedle electrodes is connected to the positive electrode of the power supply 100, and the other is connected to the negative electrode of the power supply 100.
For example, the power supply 10 has two ports a and B, and the microneedle electrode is connected to the port a or the port B, and is positive when connected to the port a, and is negative when connected to the port B. One of a set of targeted microneedle electrodes in the microneedle array 200 is connected to port a and the other is connected to port B. The remaining microneedle electrodes are not connected to the power supply 100 or disconnected from the power supply 100.
And in order to prevent the output position of the radio frequency energy from being fixed, that is, to achieve the purpose of uniform output of the radio frequency energy, the target microneedle electrode corresponding to the target coordinate in this step continuously operates at the first electrical polarity for a first preset time period T1. For example, the first preset duration may be in milliseconds.
For example, for a 7 × 7 microneedle array, it is determined that a set of target coordinates are (3,4) and (3,5), a control signal is sent to the switching circuit, so that, within a first preset time period T1, a target microneedle electrode in the microneedle array corresponding to the set of target coordinates of (3,4) and (3,5) is connected to the power supply 100 through the switching circuit, and the target microneedle electrode corresponding to (3,4) is a positive electrode and the target microneedle electrode corresponding to (3,5) is a negative electrode. At the moment, the radio frequency therapeutic apparatus provides radio frequency output through the two target micro-needle electrodes for treatment.
In step S400, the process returns to step S200. And (5) circularly executing the steps S200 to S300 until the shutdown signal is received, and finishing the treatment process of the radio frequency treatment instrument. Or the radio frequency therapy apparatus selects a traditional therapy mode.
It is easy to understand that the positive and negative electrodes of the microneedle electrodes in the conventional radio frequency therapy apparatus are fixed and are generally arranged at intervals, for example, for a 7 × 7 microneedle array, the electric polarities of the microneedle electrodes in the first row are always: positive and negative positive. In the treatment process, the energy output of the radio frequency therapeutic apparatus is uneven, so that local energy accumulation and overheating are easily caused, and the treatment effect is influenced.
In this embodiment, at least one set of target coordinates is selected from the coordinates of the plurality of microneedle electrodes in a circulating manner, the microneedle electrodes corresponding to the target coordinates are connected to the power supply through the switch switching circuit for a first preset time, and one of the two microneedle electrodes corresponding to each set of target coordinates is a positive electrode and the other is a negative electrode. Each change in the targeted microneedle electrode results in a change in the thermal diffusion zone. Therefore, in the whole treatment process, the treatment area of the radio frequency micro-needle therapeutic apparatus changes along with the coordinate transformation of the target micro-needle electrode, so that the energy control of the radio frequency therapeutic apparatus is better, the radio frequency energy output is more uniform, the treatment effect is improved, and the phenomenon that the energy is accumulated in a part of tissues and is overheated is prevented.
In this application, in step S200, the first control signal is further used to control the switch switching circuit to switch the electrical polarities of the two microneedle electrodes corresponding to each set of target coordinates at least once. For example, in the first half of the first preset time period, one of the microneedle electrodes is connected to the a port of the power supply 100 as a positive electrode, and the other is connected to the B port of the power supply 100 as a negative electrode. In the second half of the first preset time, the target microneedle electrode connected to the a port is switched to be connected to the B port, that is, to become a negative electrode, and the other target microneedle electrode, which is originally connected to the B port of the power supply 100 as a negative electrode, is changed to be connected to the a port, and to become a positive electrode. Namely, the microneedles connected with the two ends of the radio frequency power supply have different corresponding thermal dispersion areas, which are mainly caused by the characteristics of the power supply, so that the thermal dispersion areas are uneven, the treatment effect is influenced, and the influences can be eliminated by switching the power supply ends.
In the present application, in order to prevent the circuit connection between the groups of microneedle electrodes from being different due to the too large distance between each group of target coordinates, for example, if one group of microneedle electrodes is (0,0) and (0, 6), the other group is (0,2) and (3, 5). That is, it is possible that (0,0) and (0,2) are formed as a loop, and (0, 6) and (3,5) are formed as a loop, so that the predetermined therapeutic effect is not achieved. Influencing the judgment of the treatment effect of the user. Therefore, in the present application, the distance between two target coordinates in each set of target coordinates is less than or equal to the first preset distance. The first predetermined distance may be one cell. That is, optionally, two target coordinates in each set of target coordinates are coordinates corresponding to adjacent microneedle electrodes in the same row or the same column.
Further, the distance between any one target coordinate in any one group of target coordinates in the multiple groups of target coordinates and any one target coordinate in the rest groups of target coordinates is greater than or equal to a second preset distance, wherein the second preset distance is greater than the first preset distance.
That is, the microneedle electrodes corresponding to the adjacent sets of target coordinates are spaced apart, and the second preset distance may be set to 2. For example, the coordinates corresponding to the first group of microneedle electrodes are (0,0) and (0,1), and the coordinates corresponding to the second group of microneedle electrodes determined at the same time are (3,0) and (3, 1).
In this embodiment, in order to facilitate viewing of the selected record of the target coordinates and to facilitate later improvement or improvement of the control of the microneedle array, after step S200, the method further includes:
step S210, recording the at least one target coordinate.
This step is to store the target coordinates determined in step S200 as historical target coordinates in the controller, for example, a log file of the target coordinates may be formed. Or the target coordinates may be stored in a historical target coordinate library. For subsequent processing or viewing.
Further, based on the first embodiment of the radio frequency microneedle array control method of the present invention, a second embodiment of the radio frequency microneedle array control method of the present invention is provided. Referring to fig. 4, fig. 4 is a schematic flow chart of a radio frequency microneedle array control method according to a second embodiment of the present invention.
In the radio frequency treatment process, in order to avoid the determination step S200 of randomly determining the target coordinates for multiple times, if the target coordinates are repeatedly determined as the same set of coordinates for multiple times, a small probability event occurs, which may cause the electrical polarity of the microneedle electrodes of the microneedle array to be actually fixed.
In this embodiment, step S210 is included after step S200, and before step S200, the method further includes:
and S500, acquiring all historical target coordinates recorded currently.
Specifically, the method is used to obtain the stored target coordinates selected last time or several times, i.e. historical target coordinates.
S600, removing the currently recorded historical target coordinates from the coordinates corresponding to the microneedle electrodes to obtain the remaining effective coordinates.
In this step, the target coordinates selected at the last time or several times or within the treatment period are removed from the microneedle array to be selected, leaving the remaining valid coordinates. The remaining effective coordinates are the coordinates that have not been determined to correspond to the targeted microneedle electrode for the last time or for several times or during the treatment cycle. It is worth mentioning that the number of the remaining valid coordinates may be 0, which means that all coordinates in the microneedle array cannot be used in the new target coordinate determination step, so that the treatment cycle is ended, and the coordinates corresponding to all microneedle electrodes of the microneedle array need to be reloaded to start the next cycle or the treatment process is ended.
Step S200 adaptively changes to: at step S200', at least one set of target coordinates is determined from the remaining valid coordinates, wherein each set comprises two target coordinates.
Step S400 adaptively changes to: return to step S500.
That is, in this embodiment, the target coordinate is determined from the remaining effective coordinates that have not been determined as corresponding to the target microneedle electrode in the last time or several times or within the treatment period, so that the occurrence of a small probability time that a certain coordinate is repeatedly determined as the target coordinate can be avoided, thereby ensuring the uniform distribution of the target microneedle electrode of the radio frequency therapeutic apparatus over time, and thus improving the uniformity of the energy output of the radio frequency microneedle array, so as to improve the treatment effect.
For ease of understanding, the present embodiment is specifically illustrated by way of example.
For example, for a 7 × 7 microneedle array, the historical target coordinates stored in the controller are (0,0) and (0,1), (3,6) and (3,5), i.e., the target coordinates that have been used. In the new target coordinate determination step, the stored historical target coordinates (0,0) and (0,1), (3,6) and (3,5) are acquired, then the 4 coordinates are deleted from the 49 coordinates corresponding to the microneedle array, and then a new set of target coordinates, such as (2,2) and (2,3), is determined from the remaining 45 coordinates. Until the 49 coordinates are substantially selected, the next cycle is started or the radio frequency treatment is ended.
Further, based on the first embodiment and the second embodiment of the radio frequency microneedle array control method of the present invention, the third embodiment of the radio frequency microneedle array control method of the present invention is provided. Referring to fig. 5, fig. 5 is a schematic flow chart of a radio frequency microneedle array control method according to a third embodiment of the present invention.
In the treatment process of the radio frequency therapeutic apparatus, the radio frequency energy output of each microneedle electrode has a heat dispersion region, so that after each microneedle electrode is determined as a target microneedle electrode, the temperature of the tissue near the target microneedle electrode in the human tissue is higher after the treatment time of the first preset time period T1 is over. If the nearby microneedle electrode near the determined target microneedle electrode is selected in the next or several selection processes, namely, the heat diffusion areas of the continuous first preset time period T1 have overlap, so that the tissue temperature of the overlapped area cannot be cooled down, and the temperature of the part of the tissue is continuously too high due to energy accumulation, thereby affecting the treatment experience of the patient.
In this embodiment, after step S600, the method further includes:
step S700, peripheral coordinates of all the historical target coordinates are acquired.
After each recording of the historical target coordinates, the peripheral coordinates of the historical target coordinates, i.e. the coordinates located in its vicinity, can be determined. The proximity may be determined according to the particular treatment segment. For example, in one embodiment, the peripheral coordinates may be defined as microneedle electrodes spaced a distance from the target coordinates. For example, the recent history target coordinates are (3,6) and (3,5), and the peripheral coordinates are (2,6), (2,5), (4,6), (4,5) and (3, 4).
And step S800, removing the peripheral coordinates from the residual effective coordinates to obtain residual optional coordinates.
Specifically, the remaining selectable coordinates are coordinates of the microneedle array from which peripheral coordinates of the target coordinates selected for the last selection or the last selection are removed, or from which peripheral coordinates of the target coordinates selected for the last selection or the last selection are removed. It should be noted that the number of the remaining selectable coordinates may also be 0, that is, it means that all coordinates in the microneedle array cannot be used in the new target coordinate determination step, so that the treatment cycle is ended, and coordinates corresponding to all microneedle electrodes of the microneedle array need to be reloaded to start the next cycle or end the treatment process.
Step S200' is adaptively changed to: step S200 ″, including: at least one set of target coordinates is determined from the remaining selectable coordinates. Step S400 adaptively changes to: return to step S500.
In other words, in this embodiment, the target coordinate is determined from the remaining selectable coordinates that have not been determined as the target microneedle electrode in the last time or several times or in the treatment cycle, and are not the peripheral coordinates, which can avoid the occurrence of an event that the remaining coordinates are also selected as the target coordinates immediately after a certain coordinate in a certain region is selected, and prevent the occurrence of a situation that the temperature is too high due to the accumulation of the radio frequency energy in a certain tissue region treated by the radio frequency treatment apparatus, thereby ensuring the uniform distribution of the target microneedle electrodes of the radio frequency treatment apparatus in time, and improving the uniformity of the energy output of the radio frequency microneedle array, so as to improve the treatment effect.
For ease of understanding, the present embodiment is specifically illustrated by way of example.
For example, for a 7 x 7 microneedle array, the historical target coordinates stored in the controller are (0,0) and (0,1), (3,6) and (3, 5). The target coordinates of (0,0) and (0,1), (3,6) and (3,5) have already been used. Before the step of determining a new set of target coordinates, the stored historical target coordinates (0,0) and (0,1), (3,6) and (3,5), and the peripheral coordinates of the 2 sets of historical target coordinates are acquired: (0,2), (1,0), (1,1), (2,6), (2,5), (4,6), (4,5) and (3, 4). The 4 historical target coordinates and 8 peripheral coordinates are then deleted from the 49 coordinates corresponding to the microneedle array, and a new target coordinate, such as (2,4) and (2,3), is then determined from the remaining 37 coordinates.
Further, in this embodiment, the microneedle electrode corresponding to the peripheral coordinate is not selected to prevent the temperature in the tissue of a certain region from being overheated because the microneedle electrode corresponding to the peripheral coordinate is not used as the target microneedle electrode to output the radio frequency energy. Therefore, the peripheral coordinates can be returned to the microneedle array after the temperature of the partial tissue area is reduced, so that the target microneedle electrode corresponding to the peripheral coordinates can also output radio frequency energy.
Therefore, in this embodiment, after step S700, the method further includes:
and removing the peripheral coordinates of which the recording time length is greater than or equal to a second preset time length from all the peripheral coordinates.
Specifically, the recording time length may be determined according to the recording time of the history target coordinate corresponding to the peripheral coordinate. The second preset time period may be a preset cooling time. The cooling time means that the temperature of the tissue near the microneedle electrode is increased due to the output of the radio frequency energy by the microneedle electrode, and a certain time is needed to cool the microneedle electrode to the temperature capable of receiving the radio frequency again after the radio frequency output is finished. This time is the cooling time. The micro needle electrodes corresponding to the coordinates are selected again in the cooling time to output radio frequency energy, so that the radio frequency energy of tissues corresponding to the micro needle electrodes is accumulated and the temperature is overheated, the user experience is influenced, and even accidents occur.
This step re-adds perimeter coordinates that exceed the cooling time to the remaining optional coordinates of the microneedle array. Therefore, all the microneedle electrodes in the microneedle array can be determined as target microneedle electrodes to output radio frequency energy, and the improvement of the uniformity of the energy output of the radio frequency microneedle array is facilitated, so that the treatment effect is improved. The target microneedle electrodes in the microneedle array are prevented from being arranged inefficiently.
For ease of understanding, the present embodiment is specifically illustrated by way of example.
For example, for a 7 x 7 microneedle array, the historical target coordinates stored in the controller are (0,0) and (0,1), (3,6) and (3, 5). Before the step of determining a new set of target coordinates, the stored historical target coordinates (0,0) and (0,1), (3,6) and (3,5), and the peripheral coordinates of the 2 sets of historical target coordinates are acquired: (0,2), (1,0), (1,1), (2,6), (2,5), (4,6), (4,5) and (3, 4). The peripheral coordinates (2,5), (4,6), (4,5), and (3,4) that have been cooled are deleted. The 4 historical target coordinates and 4 peripheral coordinates are then deleted from the 49 coordinates corresponding to the microneedle array, and a new target coordinate, such as (2,5) and (2,4), is then determined from the remaining 41 coordinates.
In this application, the determination of the at least one target coordinate in step S200 may be a random determination, or a determination according to a certain rule. For example, in some embodiments, step S200 adaptively changes to: determining at least one set of target coordinates from the coordinates corresponding to the microneedle electrodes according to a preset target microneedle electrode sequence.
The preset target electrode sequence is a series of coordinates which are stored in advance and arranged in sequence. In step S200, target coordinates may be sequentially selected along the preset target electrode sequence.
For ease of understanding, the present embodiment is specifically illustrated by way of example.
For example, referring to fig. 6, a curve of a predetermined target electrode sequence on a coordinate system of a microneedle array starts at an origin of the microneedle array, and a set of target coordinates is determined at one step interval between a first row and a second row. Such as (0,0) and (0,1) for the first time and (2,0) and (2,1) for the second time. During the repeated execution of step S200, target coordinates are thus determined along the preset target electrode sequence. And starting the next cycle from the origin again until the preset target electrode sequence is executed. Additional preset target electrode sequences may also be performed.
Referring to fig. 7, fig. 7 is a block diagram illustrating a structure of a radio frequency micro-needle array control device according to a first embodiment of the present invention.
As shown in fig. 7, the radio frequency microneedle array control apparatus according to the embodiment of the present invention includes:
a coordinate obtaining module 10, configured to obtain coordinates corresponding to a plurality of microneedle electrodes;
a coordinate determination module 20 for determining at least one set of target coordinates from the coordinates of the plurality of microneedle electrodes, wherein each set of target coordinates comprises two target coordinates.
The signal sending module 30 is configured to send a first control signal to the switch switching circuit, so as to control the switch switching circuit to connect the target microneedle electrodes corresponding to the at least one set of target coordinates with a power supply in a first preset time period, and control the switch switching circuit to be any one of each set of target coordinates, where the target microneedle electrodes corresponding to the target coordinates supply a first electrical polarity, and to be another one of each set of target coordinates, and the target microneedle electrodes corresponding to the target coordinates supply a second electrical polarity, where the first electrical polarity is opposite to the second electrical polarity.
In this embodiment, at least one set of target coordinates is selected from the coordinates of the plurality of microneedle electrodes in a circulating manner, the microneedle electrodes corresponding to the target coordinates are connected to the power supply through the switch switching circuit for a first preset time, and one of the two microneedle electrodes corresponding to each set of target coordinates is a positive electrode and the other is a negative electrode. Each change in the targeted microneedle electrode results in a change in the thermal diffusion zone. Therefore, in the whole treatment process, the treatment area of the radio frequency micro-needle therapeutic apparatus changes along with the coordinate transformation of the target micro-needle electrode, so that the energy control of the radio frequency therapeutic apparatus is better, the radio frequency energy output is more uniform, the treatment effect is improved, and the phenomenon that the energy is accumulated in a part of tissues and is overheated is prevented.
The above description is only an alternative embodiment of the present invention, and not intended to limit the scope of the present invention, and all modifications and equivalents of the present invention, which are made by the contents of the present specification and the accompanying drawings, or directly/indirectly applied to other related technical fields, are included in the scope of the present invention.

Claims (11)

1. A radio frequency micro-needle array control method is applied to a radio frequency micro-needle therapeutic apparatus, and the radio frequency micro-needle therapeutic apparatus comprises: a power supply;
the input end of the switch switching circuit is connected with a power supply; and
a microneedle array comprising a plurality of microneedle electrodes of switchable electrical polarity, wherein each microneedle electrode has a corresponding coordinate, and the microneedle electrodes are electrically connected with an output terminal of the switching circuit;
the method comprises the following steps:
obtaining coordinates corresponding to a plurality of microneedle electrodes;
determining at least one set of target coordinates from the coordinates corresponding to the plurality of microneedle electrodes, wherein each set of target coordinates comprises two target coordinates;
sending a control signal to the switch switching circuit to control the switch switching circuit to connect the target microneedle electrodes corresponding to the at least one group of target coordinates with a power supply within a first preset time period, and controlling the switch switching circuit to supply a first electric polarity to the target microneedle electrode corresponding to any one target coordinate of each group of target coordinates and a second electric polarity to the target microneedle electrode corresponding to the other target coordinate of each group of target coordinates, wherein the first electric polarity is opposite to the second electric polarity;
returning to the step of determining at least one set of target coordinates from the coordinates corresponding to the plurality of microneedle electrodes.
2. The radio frequency microneedle array control method of claim 1, wherein after the step of determining at least one set of target coordinates from the coordinates of the plurality of microneedle electrodes, the method further comprises:
recording the at least one set of target coordinates.
3. The radio frequency microneedle array control method of claim 2, wherein prior to the step of determining at least one set of target coordinates from the coordinates corresponding to the plurality of microneedle electrodes, the method further comprises:
acquiring all historical target coordinates recorded currently;
removing the currently recorded historical target coordinates from the coordinates corresponding to the plurality of microneedle electrodes to obtain remaining effective coordinates;
the step of determining at least one set of target coordinates from the coordinates corresponding to the plurality of microneedle electrodes comprises:
at least one set of target coordinates is determined from the remaining valid coordinates.
4. The radio frequency microneedle array control method of claim 3, wherein prior to said step of determining at least one set of target coordinates from the remaining valid coordinates, said method further comprises:
acquiring peripheral coordinates of all historical target coordinates;
removing the peripheral coordinates from the residual effective coordinates to obtain residual optional coordinates;
the step of determining at least one set of target coordinates from the coordinates corresponding to the plurality of microneedle electrodes comprises:
at least one set of target coordinates is determined from the remaining selectable coordinates.
5. The radio frequency microneedle array control method of claim 4, wherein after the step of obtaining peripheral coordinates of all historical target coordinates, the method further comprises:
and removing the peripheral coordinates of which the recording time length is greater than or equal to a second preset time length from all the peripheral coordinates.
6. The radio frequency microneedle array control method of claim 1, wherein the step of determining at least one set of target coordinates from the coordinates corresponding to the plurality of microneedle electrodes comprises:
determining at least one set of target coordinates from the coordinates corresponding to the microneedle electrodes according to a preset target microneedle electrode sequence.
7. The radio frequency microneedle array control method of claim 1, wherein the control signal is further used for controlling a switching circuit to interchange the electric polarities of the two target microneedle electrodes corresponding to each set of target coordinates at least once.
8. The radio frequency microneedle array control method according to claim 1, wherein a distance between two target coordinates in each set of target coordinates is less than or equal to a first preset distance.
9. The radio frequency microneedle array control method of claim 8, wherein a distance between any one of the sets of target coordinates and any one of the remaining sets of target coordinates is greater than or equal to a second predetermined distance, wherein the second predetermined distance is greater than the first predetermined distance.
10. A radio frequency microneedle array control apparatus, comprising:
the coordinate acquisition module is used for acquiring coordinates corresponding to the microneedle electrodes;
a coordinate determination module for determining at least one set of target coordinates from the coordinates corresponding to the plurality of microneedle electrodes, wherein each set of target coordinates comprises two target coordinates;
the signal sending module is used for controlling the switch switching circuit to connect the target microneedle electrodes corresponding to the at least one group of target coordinates with a power supply in a first preset time period, and controlling the switch switching circuit to supply a first electric polarity for the target microneedle electrodes corresponding to any one target coordinate of each group of target coordinates and supply a second electric polarity for the target microneedle electrodes corresponding to another target coordinate of each group of target coordinates, wherein the first electric polarity is opposite to the second electric polarity.
11. A radio frequency micro-needle therapeutic apparatus, comprising:
a power supply;
the input end of the switch switching circuit is connected with a power supply;
a microneedle array comprising a plurality of microneedle electrodes of switchable electrical polarity, wherein each microneedle electrode has a corresponding coordinate, and the microneedle electrodes are electrically connected with an output terminal of the switching circuit; and
at least one processor, a memory, and a radio frequency microneedle array control program stored on the memory and executable on the processor, the radio frequency microneedle array control program when executed by the processor implementing the steps of the radio frequency microneedle array control method of any one of claims 1-9.
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