CN111973841A

CN111973841A - Infusion device

Info

Publication number: CN111973841A
Application number: CN201910430470.4A
Authority: CN
Inventors: 孙灿; 詹世涛
Original assignee: Shanghai Microport Lifesciences Co Ltd
Current assignee: Shanghai Microport Lifesciences Co Ltd
Priority date: 2019-05-22
Filing date: 2019-05-22
Publication date: 2020-11-24
Also published as: WO2020233689A1

Abstract

The invention provides an infusion device. In the infusion device provided by the invention, the push rod is axially movably connected with the transmission unit and used for driving the piston to move towards the liquid medicine output end, wherein the push rod can be detached from the transmission unit. Based on the structure, after all the liquid medicine is infused, the piston and the push rod can be replaced along with the liquid storage unit, so that the problem of poor infusion precision caused by abrasion of components such as the piston after long-term use is avoided; and when the liquid storage unit is replaced, the transmission unit only needs to perform circumferential reset operation, so that the abrasion of the transmission unit and the driving unit is favorably relieved, the power consumption of the driving unit is reduced, and the service life of the driving unit is prolonged.

Description

Infusion device

Technical Field

The invention relates to the technical field of medical supplies, in particular to infusion equipment.

Background

Infusion devices are one of the most commonly used articles in the medical field for achieving infusion of medical fluids. In order to achieve more precise and uniform infusion of medical fluids, a mechanical pump is commonly used to control the number of drops or flow rate of the medical fluid to ensure that the medical fluid can be infused into a patient at a uniform rate, in an accurate amount, and safely.

For example, existing insulin infusion devices with a reservoir typically have a plunger-type reservoir unit, i.e., the reservoir unit includes an inner chamber containing an insulin fluid and an administration piston. During infusion, the infusion amount of the demand is manually input through the keys, the motor is driven to rotate through a driving signal sent by the controller, the motor drives the output end push rod in the transmission structure in a mechanical transmission mode, and the push rod pushes the dosing piston of the liquid storage unit to carry out insulin infusion. In the transmission process, the controller controls the insulin liquid medicine to output the infusion amount required by the patient according to the read encoder rotation numerical value. After the insulin liquid medicine in the liquid storage unit is used up, the transmission structure and the piston need to be reset, and then a new liquid storage unit is replaced.

However, for insulin infusion devices, it is required that the infusion precision is high, with a minimum step of around 1U (i.e. 0.01 ml). With conventional infusion devices, as they are used, parts of the transmission unit wear, which further affects the infusion accuracy of the infusion device (e.g., the infusion dosage can be difficult to adjust accurately). Furthermore, the infusion of insulin is a continuous infusion, so insulin infusion devices are usually designed as portable devices with batteries. The conventional infusion device needs to perform reset operation on a replacement liquid storage unit, wherein a piston push rod moves to an initial position in the opposite direction, and the required reset time is generally 1 to 2 minutes according to different motor rotating speeds of products. Therefore, the reset procedure inevitably results in a large power consumption, which consumes a large amount of battery-efficient time of the insulin infusion device.

Disclosure of Invention

The invention aims to provide an infusion device, which aims to solve the problems that the infusion precision is poor due to the abrasion of parts and components in the existing infusion device, and the reset power consumption of the infusion device is large.

To solve the above technical problem, the present invention provides an infusion apparatus, comprising:

a drive unit;

the liquid storage unit comprises a liquid storage shell, a piston and a push rod, the liquid storage shell comprises a through inner cavity, and an opening end and a liquid medicine output end which are positioned at two ends of the inner cavity, the piston is movably and hermetically contained in the inner cavity, the push rod is abutted against the piston, and the push rod further moves axially relative to the liquid storage shell while rotating circumferentially relative to the liquid storage shell so as to drive the piston to move towards the liquid medicine output end; and the number of the first and second groups,

and the transmission unit is axially movably connected with the push rod and drives the push rod to rotate in the circumferential direction under the driving of the driving unit.

Optionally, the push rod is in threaded connection with the liquid storage shell at an opening end of the liquid storage shell, so that the push rod further moves axially along the liquid storage shell when rotating circumferentially.

Optionally, the push rod has an inner hole extending along the axial direction, and the transmission unit includes a drive shaft, a distal end of which is inserted into the inner hole of the push rod and is circumferentially fixed with the push rod.

Optionally, the driving shaft is of a rhombic column structure, and the inner hole of the push rod is of a polygonal tubular structure matched with the rhombic column structure; or, the outer wall of the driving shaft is provided with a protrusion, the inner wall of the inner hole of the push rod is provided with a groove, and the protrusion of the driving shaft is clamped with the groove of the push rod.

Optionally, the axis of the drive shaft and the axis of the push rod coincide.

Optionally, the liquid storage housing further includes a connection kit disposed at the open end, the connection kit has a first sleeve and a second threaded sleeve, the first sleeve is fixedly connected to the open end of the liquid storage housing, and the second threaded sleeve is in threaded connection with the push rod.

Optionally, the first sleeve is in threaded connection, snap-fit connection, glue bonding or melt bonding with the open end.

Optionally, an internal thread is arranged on the inner wall of the opening end, and an external thread matched with the internal thread on the opening end is arranged on the outer wall of the push rod to realize threaded connection.

Optionally, the transmission unit further includes an external gear set, where the external gear set includes a first gear and a second gear, the first gear is connected to the output shaft of the driving unit, a central shaft of the second gear is coaxially connected to the driving shaft, and the first gear drives the second gear to rotate.

Optionally, the external gear set further includes a third gear, a fourth gear and a fifth gear, the first gear is externally engaged with the third gear, the third gear is externally engaged with the fourth gear, the fourth gear and the fifth gear are coaxially arranged, and the fifth gear is externally engaged with the second gear.

Optionally, the transmission ratio of the external gear set is (3-7): 1.

optionally, the infusion device further comprises a control unit, the drive unit comprises a motor, and the control unit is configured to generate rotation number information corresponding to the motor to control rotation of the motor.

Optionally, the infusion apparatus further includes an encoder, the encoder is disposed on the motor and configured to obtain a number of turns of the motor, and the encoder is further in communication connection with the control unit to feed back the number of turns of the motor to the control unit.

Optionally, the infusion apparatus further comprises an input unit, the input unit is used for inputting infusion information, and the control unit generates rotation number information corresponding to the motor according to the infusion information and the transmission ratio of the transmission unit.

Optionally, the infusion apparatus further comprises a box body, the driving unit and the transmission unit are fixedly installed in the box body, and the liquid storage unit is detachably installed in the box body.

Optionally, an accommodating hole is formed in the cartridge, and the cartridge is configured to accommodate the liquid storage unit and limit circumferential rotation of the liquid storage unit.

Optionally, the infusion device further includes an infusion set connector detachably connected to the cassette at the opening of the receiving hole, and the infusion set connector further abuts against the liquid storage unit received in the receiving hole to limit axial movement of the liquid storage unit.

Optionally, the infusion device further comprises a first wireless communication unit, and an input assembly separate from the housing; wherein,

the first wireless communication unit is arranged on the box body and is in communication connection with the control unit;

The input assembly comprises an input unit and a second wireless communication unit, the input unit is used for inputting infusion information and is in communication connection with the second wireless communication unit, and the first wireless communication unit is in wireless communication connection with the second wireless communication unit;

and the control unit generates rotation number information corresponding to the motor according to the infusion information and the transmission ratio of the transmission unit.

In the infusion apparatus provided by the invention, the push rod of the liquid storage unit is axially movably connected with the transmission unit, namely, the push rod of the liquid storage unit is not fixedly connected with the transmission unit, so that the components such as the liquid storage unit, the piston, the push rod and the like can be separated from the transmission unit and the driving unit for driving the transmission unit. Based on this, can be after the stock solution unit discharges all liquid medicines, parts such as piston and push rod can be replaced along with the stock solution unit together, have avoided subassembly such as piston to have wearing and tearing after long-term the use and influence its infusion precision's problem.

Furthermore, based on the transmission unit only rotates in the circumferential direction and does not move in the axial direction, after all liquid medicine is discharged from the current liquid storage unit, the transmission unit only needs to perform circumferential resetting operation and does not need to perform axial resetting operation. Therefore, the abrasion and the power consumption of the transmission unit and the driving unit can be effectively reduced, and the service lives of the transmission unit and the driving unit can be prolonged.

Drawings

FIG. 1 is a schematic diagram of an infusion device in one embodiment of the invention;

FIG. 2 is a schematic diagram of an infusion device during an infusion procedure thereof in accordance with an embodiment of the present invention;

FIG. 3a is a schematic cross-sectional view of a pushrod and drive shaft of an infusion device in an embodiment of the invention, taken perpendicular to the axial direction;

FIG. 3b is a schematic cross-sectional view of another push rod and drive shaft of an infusion device in an embodiment of the disclosures made herein, taken perpendicular to the axial direction;

FIG. 3c is a schematic cross-sectional view of a further push rod and drive shaft of an infusion device in an embodiment of the disclosures made herein, taken perpendicular to the axial direction;

FIG. 4 is a schematic view of the transmission unit of the infusion device in one embodiment of the present invention;

fig. 5 is a schematic structural diagram of a cassette of an infusion apparatus according to an embodiment of the present invention.

Wherein the reference numbers are as follows:

100-a liquid storage unit;

110-a reservoir housing;

110A-liquid medicine output end;

120-a push rod;

130-a connection kit;

130A-a first sleeve;

130B-a second threaded sleeve;

140-a piston;

200-a transmission unit;

210-a drive shaft;

210A-bumps;

230-external gear set;

231-a first gear;

232-a second gear;

233-third gear;

234-fourth gear;

235-fifth gear;

300-a control unit;

400-an encoder;

500-an input unit;

600-a cartridge;

700-a display unit;

800-a drive unit;

900-infusion set joint.

Detailed Description

The infusion device according to the invention will be described in more detail below with reference to the figures and the embodiments. The advantages and features of the present invention will become more apparent from the following description. It is to be noted that the drawings are in a very simplified form and are not to precise scale, which is merely for the purpose of facilitating and distinctly claiming the embodiments of the present invention.

In the present embodiment, the liquid medicine stored in the liquid storage unit 100 of the infusion device is insulin liquid medicine, i.e. the infusion device is used for controlling hyperglycemia for exemplary illustration.

Fig. 1 is a schematic structural diagram of an infusion device in an embodiment of the present invention, and fig. 2 is a schematic structural diagram of an infusion device in an embodiment of the present invention during an infusion process thereof. Referring to fig. 1 and 2, in the present embodiment, the infusion apparatus includes:

the liquid storage unit 100, the liquid storage unit 100 comprises a liquid storage shell 110, a push rod 120 and a piston 140; the liquid storage shell 110 is provided with a through inner cavity, an opening end positioned at two ends of the inner cavity and a liquid medicine output end 110A; the piston 140 is movably and hermetically accommodated in the inner cavity; the push rod 120 abuts against the piston 140, and when the push rod 120 rotates circumferentially relative to the reservoir housing 110, the push rod 120 also moves axially relative to the reservoir housing 110 to drive the piston 140 to move towards the liquid medicine output end;

A driving unit 800;

one end of the transmission unit 200 is connected to the driving unit 800, and the other end of the transmission unit 200 is axially movably connected to the push rod 120, so that the transmission unit 200 drives the push rod 120 to rotate in the circumferential direction under the driving of the driving unit 800.

That is, the driving unit 800 drives the transmission unit 200 to further drive the push rod 120 to rotate circumferentially through the transmission unit 200, so that the push rod 120 can move axially along the liquid storage housing 110 while rotating circumferentially, and further the insulin liquid medicine in the liquid storage housing 110 can be delivered out from the liquid medicine output end 110A of the liquid storage housing 110. In a preferred embodiment, the driving unit 800 includes a motor and an energy provider.

In this embodiment, the push rod 120 can be screwed to the reservoir housing 110 at the open end of the reservoir housing. In this way, the push rod 120 can move axially along the reservoir housing 110 when the push rod 120 rotates in the circumferential direction, under the restriction of the threaded engagement. The embodiment is not particularly limited to the embodiment that the push rod 120 can move along the axial direction of the liquid storage housing 110 when rotating in the circumferential direction, and can also be implemented by using a method such as a worm gear and a worm.

It should be noted that, because the transmission unit 200 and the push rod 120 are axially movably connected along the axial direction of the push rod, that is, the transmission unit 200 and the push rod 120 are axially non-fixedly connected, the push rod 120 can be detached from the transmission unit 200. Equivalently, the liquid storage unit 100 is detachably connected to the transmission unit 200 and the driving unit 800. Therefore, on one hand, after the liquid storage unit 100 discharges all insulin liquid medicine, the push rod 120, the piston 140 and other parts can be replaced along with the liquid storage unit 100, and the problem that the infusion precision is deviated due to abrasion after long-term use because the parts such as the piston cannot be replaced in the existing infusion equipment is solved; on the other hand, the problems of the existing infusion apparatus that the transmission unit 200 is required to perform a long-time reset operation when the storage unit 100 with the insulin liquid medicine is replaced with a new storage unit 100 with the insulin liquid medicine after the insulin liquid medicine in the storage unit 100 is completely discharged are solved, that is, in the present embodiment, the reset operation performed by the transmission unit 200 is simpler, only circumferential reset is required, and axial reset is not required any more, so that the reset time is reduced. Simple resetting and short time consumption can reduce the abrasion of the motor and the transmission unit 200, maintain the infusion precision, increase the service life of the energy supplier and prolong the single energy supply time.

With continued reference to fig. 1, in the present embodiment, the transmission unit 200 includes a driving shaft 210, so that the driving shaft 210 drives the push rod 120 to rotate circumferentially.

Specifically, the push rod 120 has an inner hole extending along the axial direction, the distal end of the driving shaft 210 of the transmission unit 200 is inserted into the inner hole of the push rod 120, and the driving shaft 210 is circumferentially fixed with the push rod 120 through the inner hole, so that the driving shaft 210 can simultaneously drive the push rod 120 to circumferentially rotate when circumferentially rotating.

Fig. 3a is a schematic cross-sectional view of a pushrod and drive shaft of an infusion device in an embodiment of the invention taken perpendicular to the axial direction, fig. 3b is a schematic cross-sectional view of a pushrod and drive shaft of an infusion device in an embodiment of the invention taken perpendicular to the axial direction, and fig. 3c is a schematic cross-sectional view of a pushrod and drive shaft of an infusion device in an embodiment of the invention taken perpendicular to the axial direction. As shown in fig. 1 and fig. 3a to 3c, the shape of the driving shaft 210 matches the shape of the inner hole of the push rod 120.

In an optional scheme, the driving shaft 210 is a rhombic column structure, and the inner hole of the push rod 120 is correspondingly a polygonal cylinder structure matched with the rhombic column structure, so that the driving shaft 210 and the push rod 120 are circumferentially fixed. Referring specifically to fig. 3a, the driving shaft 210 has a structure of, for example, a rhombus column, and the inner hole of the push rod 120 has a corresponding triangular tubular structure, that is, the cross-sectional shapes of the driving shaft 210 and the inner hole of the push rod 120 in the direction perpendicular to the axial direction are corresponding triangles; alternatively, referring to fig. 3b, the driving shaft 210 has a quadrangular prism-shaped structure, and the inner hole of the push rod 120 has a quadrangular cylinder-shaped structure, that is, the cross-sectional shapes of the driving shaft 210 and the inner hole of the push rod 120 in the direction perpendicular to the axial direction are quadrangular. Alternatively, the driving shaft 210 may also have another polygonal prism-shaped structure, which is not described herein.

Of course, in other alternative schemes, the circumferential fixation between the driving shaft 210 and the push rod 120 can also be achieved by a snap-fit manner. For example, referring to fig. 3c, the outer wall of the driving shaft 210 has a protrusion 210A extending along a radial direction, and the inner wall of the inner hole of the push rod 120 has a corresponding groove recessed along a radial direction, and when the driving shaft 210 is inserted into the inner hole of the push rod 120, the protrusion 210A of the driving shaft 210 is snapped onto the groove of the inner hole. In this manner, circumferential movement of the drive shaft 210 relative to the push rod 120 is avoided. Further, the protrusion 210A on the driving shaft 210 extends axially along the outer wall of the driving shaft, for example, to present a strip-like structure. The grooves of the inner bore of the push rod extend in the axial direction to match the protrusions 210A of the bar-like structure.

Further, the axis of the driving shaft 210 coincides with the axis of the push rod 120, that is, the driving shaft 210 and the push rod 120 are arranged coaxially, so that the stability in the transmission process can be further improved, the centrifugal phenomenon is avoided, and more accurate driving control is realized. In this embodiment, the axis of the inner hole of the push rod 120 may coincide with the axis of the push rod 120, so that the driving shaft 210 and the push rod 120 are coaxially arranged.

As described above, in the present embodiment, when the push rod 120 is driven by the driving shaft 210 to rotate circumferentially, the push rod 120 can move axially under the limitation of the threaded engagement at the open end of the liquid storage housing 110. Thus, when the push rod 120 rotates in the circumferential direction, the push rod 120 also moves axially relative to the drive shaft 210. It is considered that the push rod 120 and the drive shaft 210 are axially movably connected by a push rod inner bore. For example, the push rod 120 and the drive shaft 210 may be a clearance fit such that the push rod 120 may move axially relative to the drive shaft 210. Based on this, the inner wall of the inner hole of the push rod 120 and the outer surface of the driving shaft 210 may both be made of low friction material, for example, so that the push rod 120 can move smoothly relative to the driving shaft 210.

With continued reference to fig. 1 and 2, in this embodiment, the reservoir housing 110 further includes a connection assembly 130, and the connection assembly 130 is disposed at an open end of the reservoir housing 110, so that the push rod 120 is connected to the open end of the reservoir housing 110 through the connection assembly 130. Specifically, the connection kit 130 includes a first sleeve 130A and a second threaded sleeve 130B connected to each other, the first sleeve 130A is matched with the open end of the liquid storage housing 110 to be fixedly connected with the open end of the liquid storage housing 110, and the second threaded sleeve 130B is matched with the push rod 120 and is threadedly connected with the push rod 120.

Wherein the first sleeve 130A and the open end can be fixedly connected by, for example, screwing, snapping, gluing or melting, so as to connect the first sleeve 130A and the reservoir housing 110.

In this embodiment, the inner wall of the first sleeve 130A has an internal thread, and the outer wall of the opening end has an external thread matching with the internal thread, so that the first sleeve 130A can be sleeved on the periphery of the opening end and is in threaded connection with the outer wall of the opening end. Alternatively, in other embodiments, the first sleeve 130A may have an external thread on its outer wall and a matching internal thread on its inner wall, and the first sleeve 130A and the inner wall of the open end are fixedly connected by a screw member.

And an inner thread is arranged on the inner wall of the second threaded sleeve 130B, an outer thread is arranged on the outer wall of the push rod 120, and the second threaded sleeve 130B is sleeved on the periphery of the push rod 120 so that the second threaded sleeve 130B is in threaded connection with the outer wall of the push rod 120. Also, the push rod 120 may rotate circumferentially relative to the second threaded sleeve 130B and move the push rod 120 axially under the restriction of the threaded engagement.

In this embodiment, the push rod 120 is screwed to the open end of the liquid storage housing 110 through a connection assembly 130. However, in other embodiments, the push rod 120 may also be directly connected to the open end of the liquid storage housing 110, for example, an inner thread is provided on an inner wall of the open end, and an outer wall of the push rod is provided with an outer thread matching with the inner thread on the open end, so as to realize direct threaded connection of the push rod 120 with the open end. More specifically, the internal thread provided on the open end may be protruded from an inner wall of the open end.

With continued reference to fig. 1 and 2, the piston 140 is movably disposed within the reservoir housing 110, and the shape of the piston 140 matches the shape of the interior cavity of the reservoir housing 110 such that the piston 140 can sealingly engage the interior walls of the reservoir housing 110. Further, a silica gel ring is further arranged on the outer side of the piston 140, and the diameter of the silica gel ring is slightly larger than that of the inner cavity, so that the sealing performance between the piston 140 and the inner cavity is further improved.

And, the piston 140 also abuts the push rod 120. Specifically, the end of the piston 140 away from the liquid medicine output end 110A of the liquid storage housing abuts against the push rod 120, so that when the push rod 120 moves axially, the push rod 120 can drive the piston 140 to move axially. For example, when the infusion device infuses insulin fluid, the push rod 120 pushes the piston 140 to move the piston 140 in a direction toward the fluid output port 110A so that the insulin fluid in the reservoir housing 110 may be expelled from the fluid output port 110A.

With continued reference to fig. 1 and 2, the drive unit 200 further includes an external gear set 230. The external gear set 230 in the present embodiment will be described in detail below with reference to the drawings.

Fig. 4 is a schematic diagram of an external gear set of an infusion device according to an embodiment of the present invention, and referring to fig. 4, the external gear set 230 includes a first gear 231 and a second gear 232. Wherein the first gear 231 is connected to an output shaft of a motor of the driving unit 800 (specifically, a central axis of the first gear 231 may be coaxially connected to the output shaft of the motor); the central axis of the second gear 232 is coaxially connected to the driving shaft 210, so that the first gear 231 is utilized to drive the second gear 232 to rotate, thereby driving the driving shaft 210 to rotate.

In this embodiment, the first gear 231 is a small gear relative to the second gear 232, and the second gear 232 is a large gear relative to the first gear 231, so that a transmission manner that the small gear (i.e., the first gear 231) drives the large gear (i.e., the second gear 232) is correspondingly realized, which is beneficial to achieving a larger reduction ratio and improving the control precision of the driving shaft 210. Further, the transmission ratio of the external gear set 230 is (3-7): 1, namely, the transmission ratio of the transmission unit 200 can be realized by using the external gear set 230, for example, (3-7): 1, since the transmission speed of the driving wheel at the starting end of the transmission unit 200 is greater than that of the driven wheel at the tail end thereof, it is beneficial to improve the control accuracy of the driving speed of the push rod 120.

Further, the second gear 232 is coaxially disposed at the proximal end of the driving shaft 210 to drive the driving shaft 210 to rotate circumferentially, and the distal end of the driving shaft 210 is inserted into the push rod 120. Wherein the proximal end and the distal end of the drive shaft 210 are opposite ends.

It should be noted that the number of gears in the external gear set 230 can be adjusted according to actual conditions. For example, at least one gear may be added between the first gear 231 and the second gear 232 to further adjust the gear ratio of the first gear 231 and the second gear 232 in the external gear set 230 to address the space limitation of the infusion apparatus on the size of the gears.

With continued reference to fig. 4, in the present embodiment, the external gear set 230 is explained by taking an example in which there are 5 gears, the 5 gears are a first gear 231, a second gear 232, a third gear 233, a fourth gear 234 and a fifth gear 235, respectively, and the axes of the five gears are parallel or collinear.

The first gear 231 is coaxially fixed on the output shaft of the motor, the first gear 231 is externally engaged with the third gear 233, the third gear 233 is externally engaged with the fourth gear 234, the fourth gear 234 and the fifth gear 235 are coaxially arranged, and the fifth gear 235 is externally engaged with the second gear 232.

It should be appreciated that the structure of one external gear set 230 of the present embodiment is shown only schematically in fig. 4. In other embodiments, only the first gear 231 and the second gear 232 may be provided, and the first gear 231 and the second gear 232 may be externally engaged; alternatively, only a fourth gear and a fifth gear may be additionally provided between the first gear 231 and the second gear 232, and the first gear 231 and the fourth gear may be externally engaged, the fourth gear and the fifth gear may be coaxially disposed, and the fifth gear 235 and the second gear 232 may be externally engaged.

That is, the arrangement of the gears in the external gear set 230 may be adjusted according to actual requirements, for example, the gears may be correspondingly arranged according to the transmission ratio to be achieved by the external gear set 230.

Further, the motor in the driving unit 800 is configured to generate a driving force, so as to drive the push rod 120 to rotate circumferentially through the transmission unit 200. In practical applications, an appropriate motor may be selected according to parameters such as power, transmission ratio, and the like. The motor can adopt a direct current speed reducing motor, such as a gear speed reducing motor. The energy provider in the drive unit 800 may be an electrochemical storage system (e.g. alkaline battery, lithium battery), an electrical storage system (e.g. super capacitor).

With continued reference to fig. 1 and 2, the infusion device further comprises a control unit 300, the control unit 300 being adapted to control the rotation of the motor. The control unit 300 is, for example, a single chip, a PLC, an FPGA, or a microprocessor.

Furthermore, the control unit 300 may be further configured to receive infusion information, including, for example: infusion time, volume of infusion per time, and drug solution concentration in the reservoir unit 100. And the control unit 300 may further combine the infusion information such as the infusion amount and the concentration of the liquid medicine in the liquid storage unit 100 for each time and the transmission ratio of the transmission unit to generate information corresponding to the number of rotations of the motor. Further, the control unit 300 may also determine when to drive the motor to rotate according to the infusion time.

In this embodiment, the infusion apparatus further comprises an input unit 500 for inputting the infusion information. And, the input unit 500 is further communicatively connected to the control unit 300 so that the input infusion information can be transmitted to the control unit 300. Specifically, the input unit 500 includes, for example, an input key; alternatively, the input unit 500 may further include a touch screen or the like.

Further, the infusion device further comprises an encoder 400. The encoder 400 is disposed on the motor for acquiring the number of turns of the motor, and is in communication connection with the control unit 300 to notify the control unit 300 of the actual number of turns of the motor. Alternatively, the encoder 400 may be a rotary encoder, for example, and further may be an incremental rotary encoder, for example.

Specifically, the control unit 300 generates information corresponding to the number of turns of the motor and controls the turning on of the motor in conjunction with the infusion time. The encoder 400 acquires the current number of rotations of the motor and generates feedback information, and then transmits the feedback information to the control unit 300. At this time, the control unit 300 may generate corresponding information to control the motor to be turned off in combination with the feedback information. Thus, the purpose of real-time regulation and control can be realized through the control unit 300.

Further, the infusion apparatus further comprises a box body, the liquid storage unit 100 is detachably installed in the box body, and the transmission unit 200 and the driving unit 800 are both arranged in the box body.

Fig. 5 is a schematic structural diagram of a cassette of an infusion apparatus according to an embodiment of the present invention, and as shown in fig. 5, in this embodiment, the driving unit 800, the transmission unit 200, the control unit 300, the encoder 400, and the input unit 500 may all be fixedly disposed in the cassette 600, and the liquid storage unit 100 is detachably mounted in the cassette 600. That is, after the infusion device completes the infusion, the reservoir unit 100 may be directly removed and replaced with a new reservoir unit containing insulin solution. It should be appreciated that when replacing the infused reservoir unit 100, the piston and pushrod components of the infused reservoir unit 100 are replaced accordingly.

Optionally, an accommodating hole is formed in the case 600, and is used for accommodating the liquid storage unit 100, and the liquid storage unit 100 is further circumferentially clamped in the accommodating hole. Specifically, the outermost contour of the liquid storage unit 100 may be a rhombic structure (that is, the contour of the liquid storage unit 100, for example, the liquid storage housing 110 and/or the connection kit 130, contacting the accommodation hole is a rhombic structure), and the accommodation hole is a polygonal cylindrical structure, so that the liquid storage unit 100 and the cartridge 600 are circumferentially fixed, and further, when the driving unit 800 is used to drive the push rod 120 to rotate, the liquid storage housing 110 is prevented from being driven to rotate.

In this embodiment, the first sleeve 130A of the connection kit 130 protrudes from the liquid storage housing 110, and based on this, the outer contour of the first sleeve 130A can be configured as a rhombic structure. In this case, the outer contour of the reservoir housing 110 may not be limited.

It should be noted that, the circumferential fixation of the liquid storage unit 100 with respect to the cartridge 600 means that the whole liquid storage unit 100 is circumferentially fixed with respect to the cartridge 600, however, some components of the liquid storage unit 100 may circumferentially rotate with respect to the liquid storage unit 100, for example, during the infusion process of the liquid storage unit 100, the push rod 120 may still circumferentially rotate.

Further, the infusion device further comprises an infusion set connector 900, wherein the infusion set connector 900 is used for limiting the axial movement of the liquid storage unit 100. Specifically, the syringe adapter 900 is detachably connected to the cassette 600 at the opening of the receiving hole, for example, by a screw, a snap, or the like. Further, after the infusion set connector 900 is configured to be completely matched with the cassette 600, the infusion set connector 900 is disposed at the opening of the accommodating hole and abuts against the liquid medicine output end of the liquid storage unit 100, so as to limit the axial movement of the liquid storage unit 100. And, when replacing the infused liquid storage unit 100, the infusion set connector 900 may be detached from the cassette body 600 to further remove the infused liquid storage unit 100 from the opening of the receiving hole.

Further, the infusion device delivers insulin solution to the subject via an infusion set. Wherein, the proximal end of the infusion component comprises a needle which is penetrated and a tube which is connected with the needle. The infusion set connector 900 includes a connecting lumen therethrough for receiving the tubing and needle. The liquid medicine output end 110A of the liquid storage unit 100 is sealed by a sealing member (e.g., a silicone plug) to prevent the insulin liquid medicine from flowing out. When the infusion set is used, the infusion set penetrates through the connecting cavity and pierces the sealing element of the liquid medicine output end 110A of the liquid storage unit 100, and insulin liquid medicine can flow to the pipe through the needle and then enters a receptor. At this point, the syringe adapter 900 mates with the cartridge 600 to secure the reservoir unit 100 relative to the cartridge 600.

With continued reference to fig. 4, when the liquid storage unit 100 is mounted in the accommodating hole, the driving shaft 210 of the transmission unit 200 can be inserted into the push rod 120 of the liquid storage unit 100. And the axis of the liquid storage unit 100 may coincide with the axis of the accommodation hole.

As shown in fig. 4, the input unit 500 is disposed on a surface of the cassette body 600 to facilitate input of infusion information. Further, a display unit 700 is further provided on a surface of the cassette body 600 to display infusion information of the infusion apparatus using the display unit 700. For example, information such as the concentration of the medical fluid and the infusion dose entered from the input unit 500, the infusion time, the input dose, etc. may be displayed on the display unit 700. Here, the display unit 700 is not particularly limited, and may be a liquid crystal display, an LED dot matrix screen, or the like.

In an alternative embodiment, the input unit 500 and/or the display unit 700 are not provided on the case 600 but as a separate component. At this time, the input unit 500 and/or the display unit 700 are connected to the control unit 300 by wireless communication. The specific communication method is not particularly limited in this embodiment, and any one of Infrared (IR), Bluetooth (Bluetooth), NFC, Zigbee, Wifi, cellular communication, and the like may be used.

Specifically, in an alternative embodiment, the infusion device further includes a first wireless communication unit, and an input assembly separate from the housing 600. Further, the first wireless communication unit is disposed in the box 600 and is in communication connection with the control unit 300. The input assembly comprises an input unit and a second wireless communication unit, the input unit is used for inputting infusion information and is in wireless communication connection with the second wireless communication unit, and the first wireless communication unit is in wireless communication connection with the second wireless communication unit; furthermore, when the infusion information is inputted by the input unit, the infusion information can be transmitted to the first wireless communication unit through the second wireless communication unit, and further transmitted to the control unit 300 through the first wireless communication unit. And the control unit 300 generates information on the number of turns of the motor according to the infusion information and the transmission ratio of the transmission unit.

To further illustrate the infusion device in this embodiment and to realize the advantages of the infusion device in this embodiment, the operation of the infusion device in this embodiment to infuse insulin liquid is explained below with reference to fig. 1 and 2.

First, after the reservoir unit 100 storing the insulin liquid medicine is mounted, infusion information is entered using the input unit 500 and the start of infusion is instructed.

Next, the control unit 300 generates information on the number of rotations of the motor according to the infusion information and the transmission ratio of the transmission unit 200, and controls the motor to be turned on at the time of infusion.

Then, the motor drives the transmission unit 200, so that the driving shaft 210 of the transmission unit 200 drives the push rod 120 in the liquid storage unit 100 to rotate circumferentially, and meanwhile, the encoder 400 obtains the actual number of rotations of the motor and feeds the actual number of rotations back to the control unit 300; the push rod 120 is driven to rotate circumferentially and simultaneously moves axially relative to the liquid storage shell to push the piston 140 to move towards the liquid medicine output end 110A, so that the insulin liquid medicine in the liquid storage shell 110 is discharged from the liquid medicine output end 110A;

next, the control unit 300 compares the number of turns of the rotation with the actual number of turns of the motor obtained from the encoder 400, and when the condition is satisfied, the control unit 300 controls the motor to be turned off until the next infusion timing.

After the infusion of all the liquid medicines is completed, the liquid storage unit 100 may be directly detached from the cassette body 600, and then the transmission unit 200 is reset (in this embodiment, specifically, the drive shaft 210 of the transmission unit 200 is circumferentially reset), and a new liquid storage unit storing the insulin liquid medicine may be replaced.

It should be noted that during the infusion process, when the push rod 120 is axially moved, the drive shaft 210 only rotates circumferentially and does not move axially. Therefore, when the liquid storage unit storing the insulin liquid medicine is mounted again, the driving shaft 210 does not need to be axially reset, the driving shaft only needs to be reset to the initial position in the circumferential direction, and then when the liquid storage unit is mounted in the cartridge 600, the driving shaft 210 can be inserted into the push rod 120 of the liquid storage unit in an aligned manner.

For example, the drive shaft 210 rotates a total of 310.3 revolutions from the beginning of use of the reservoir unit 100 to the end of the reservoir unit 100. While the output end push rod of the transmission unit of the traditional insulin infusion device needs to rotate reversely for 301.3 circles to realize circumferential and axial reset, the drive shaft 210 only needs to rotate reversely for 0.3 circle to realize reset by adopting the infusion device of the embodiment. Therefore, the abrasion of the transmission unit 200 can be effectively reduced, the reset time is saved, and the electric quantity loss is reduced.

In summary, in the infusion apparatus provided by this embodiment, the liquid storage unit includes a liquid storage housing, a piston, and a push rod, wherein the push rod abuts against the piston, and when the push rod rotates circumferentially relative to the liquid storage housing, the push rod further moves axially relative to the liquid storage housing to drive the piston to move; the transmission unit is movably connected with the push rod in the axial direction of the push rod, and the drive unit drives the push rod to rotate in the circumferential direction. Compare with current insulin infusion equipment, utilize the infusion equipment that this embodiment provided to after insulin liquid medicine is all infused, piston, push rod can be replaced along with the stock solution unit together, avoid subassembly such as piston to have wearing and tearing and lead to infusing the not good problem of precision after long-term the use. Therefore, when the infusion device of the embodiment is used for infusion, the infusion dose adjusting precision is high, the infusion dose is more uniform, and the risk of unstable blood sugar of a patient is reduced.

In addition, in the infusion apparatus of the embodiment, after the infusion of all the insulin liquid medicine in the current liquid storage unit is completed, the resetting operation is simple when the transmission unit is reset, and the resetting can be realized only by rotating the driving shaft for less than one turn. Therefore, the loss of the transmission unit and the motor is reduced, and the service time of the energy donor is prolonged.

In the above embodiments, the liquid medicine stored in the liquid storage unit 100 of the infusion apparatus is insulin liquid medicine for illustrative purposes only and is not meant to limit the present invention. It will be appreciated by those skilled in the art that the medical fluid stored by the reservoir unit 100 in the infusion device is not limited to insulin medical fluids, but may be other medical fluids, such as gonadorelin (gonadorelin) for treating infertility due to hypogonadotropic hypogonadism, etc.

The above description is only for the purpose of describing the preferred embodiments of the present invention, and is not intended to limit the scope of the present invention, and any variations and modifications made by those skilled in the art based on the above disclosure are within the scope of the appended claims.

Claims

1. An infusion device, comprising:

a drive unit;

2. The infusion device as claimed in claim 1, wherein said push rod is threadably connected to said reservoir housing at an open end thereof such that said push rod also moves axially along said reservoir housing when rotated circumferentially.

3. The infusion device of claim 2, wherein the pushrod has an inner bore extending in an axial direction, the transmission unit including a drive shaft having a distal end inserted into the inner bore of the pushrod and circumferentially fixed thereto.

4. The infusion device as claimed in claim 3, wherein said drive shaft is of a rhomb-cylindrical configuration and said push rod has an internal bore of a polygonal cylindrical configuration matching said rhomb-cylindrical configuration; or, the outer wall of the driving shaft is provided with a bulge, the inner wall of the inner hole of the push rod is provided with a groove, and the bulge of the driving shaft and the groove of the push rod are mutually clamped.

5. The infusion device of claim 3, wherein an axis of the drive shaft and an axis of the push rod coincide.

6. The infusion device of claim 2, wherein the reservoir housing further comprises a connection assembly disposed at the open end, the connection assembly including a first sleeve fixedly coupled to the open end of the reservoir housing and a second threaded sleeve threadably coupled to the pushrod.

7. The infusion device as claimed in claim 6, wherein said first sleeve is threaded, snap-fit, glue-bonded or melt-bonded to said open end.

8. The infusion device as claimed in claim 2, wherein the inner wall of the open end is provided with an internal thread and the outer wall of the push rod is provided with an external thread matching the internal thread of the open end to effect a threaded connection.

9. The infusion device as claimed in claim 3, wherein said transmission unit further comprises an external gear set, said external gear set comprising a first gear and a second gear, said first gear being connected to an output shaft of said drive unit, a central axis of said second gear being coaxially connected to said drive shaft, said first gear driving said second gear to rotate.

10. The infusion device of claim 9, wherein the set of external gears further comprises a third gear, a fourth gear, and a fifth gear, the first gear being in external mesh with the third gear, the third gear being in external mesh with the fourth gear, and the fourth gear and the fifth gear being coaxially arranged, the fifth gear being in external mesh with the second gear.

11. The infusion device of claim 9, wherein the external gear set has a gear ratio of (3-7): 1.

12. the infusion device as claimed in claim 1, further comprising a control unit, the drive unit comprising a motor, the control unit for generating rotation count information corresponding to the motor to control rotation of the motor.

13. The infusion device as claimed in claim 12, further comprising an encoder disposed on the motor for obtaining a number of rotations of the motor, and the encoder is further communicatively connected to the control unit for feeding back the number of rotations of the motor to the control unit.

14. The infusion device as claimed in claim 12, further comprising an input unit for inputting infusion information, the input unit being communicatively connected to the control unit, the control unit generating information corresponding to a number of rotations of the motor based on the infusion information and a gear ratio of the transmission unit.

15. The infusion device as claimed in claim 1, further comprising a cassette, wherein the drive unit and the transmission unit are fixedly mounted within the cassette, and wherein the reservoir unit is removably mounted within the cassette.

16. The infusion device as claimed in claim 15, wherein the cassette has an accommodating hole therein and is configured to receive the reservoir unit and restrict circumferential rotation of the reservoir unit.

17. The infusion device as claimed in claim 16, further comprising an infusion set connector removably connected to the cassette at the opening of the receiving aperture and further abutting a reservoir unit received in the receiving aperture to limit axial movement of the reservoir unit.

18. The infusion device of claim 15, further comprising a first wireless communication unit, and an input assembly separate from the housing; wherein,