CN111966018B

CN111966018B - Bile information acquisition equipment, method, device and system

Info

Publication number: CN111966018B
Application number: CN202010848062.3A
Authority: CN
Inventors: 许晓珊; 吴懿苗; 梁铭炬; 周伟津; 杨树进; 刘华敏; 何锡然; 邝伟健
Original assignee: Guangdong Shunde Industrial Design Institute
Current assignee: Guangdong Shunde Industrial Design Institute
Priority date: 2020-08-21
Filing date: 2020-08-21
Publication date: 2022-04-22
Anticipated expiration: 2040-08-21
Also published as: CN111966018A

Abstract

The application relates to bile information acquisition equipment, a method, a device and a system. The bile information collecting apparatus includes: a bile duct for conducting bile from a bile duct into the droplet generator, a titration sensor and a bile collector; the liquid drop generator is connected with the bile duct; the liquid drop generator is used for generating bile liquid drops so that bile drops into the bile collector; the titration sensor is arranged on the liquid drop generator and is also used for connecting an upper computer; the titration sensor is used for detecting the bile liquid drops passing through and generating corresponding bile liquid drop signals to be sent to an upper computer; the bile collector is connected with the titration sensor and is used for collecting bile liquid drops dripped from the liquid drop generator. This bile information acquisition equipment can turn into digital signal with the bile liquid drop and realize labour saving and time saving to the automatic acquisition of bile liquid drop.

Description

Bile information acquisition equipment, method, device and system

Technical Field

The application relates to the technical field of body temperature mechanical perfusion, in particular to bile information acquisition equipment, method, device and system.

Background

With the development of organ transplantation technology, a body temperature mechanical perfusion technique has emerged, by which human or non-human organs can be preserved for a long time before transplantation into a patient. Taking liver as an example, in the mechanical perfusion process of body temperature, the bile secretion amount is generally used as an important basis for evaluating the functional state of the perfused liver.

In traditional body temperature machinery perfusion technique, the bile is the bile duct of the intubate connection liver through the bile, uses the test tube that has the scale to collect, and the change of secretion is recorded in real time by medical staff again, assesss the functional state of liver according to the situation of change. For the liver requiring long-time perfusion, the bile is collected in an artificial statistics mode, and the defects of time and labor waste exist.

Disclosure of Invention

Based on this, it is necessary to provide a new bile information collecting device, method, apparatus and system to overcome the disadvantages of the prior art, aiming at the problem that the conventional counting is time-consuming and labor-consuming.

A bile information acquisition device comprises a bile duct, a liquid drop generator, a titration sensor and a bile collector,

the bile duct is used for guiding bile from the bile duct into the liquid drop generator;

the liquid drop generator is connected with the bile duct; the liquid drop generator is used for generating bile liquid drops so that bile drops into the bile collector;

the titration sensor is arranged on the liquid drop generator and is also used for connecting an upper computer; the titration sensor is used for detecting the bile liquid drops passing through and generating corresponding bile liquid drop signals to be sent to an upper computer;

the bile collector is connected with the titration sensor and is used for collecting bile liquid drops dripped from the liquid drop generator.

In one embodiment, the liquid drop generator comprises a bile inlet section and a bile dropping pipe, wherein the bile inlet section penetrates through and extends into the bile dropping pipe, and a bile outlet is formed in the bottom of the bile dropping pipe; the bile inlet section is connected with a bile duct, and the bile collector is arranged at the bile outlet.

In one embodiment, the bile collector comprises a collecting pipe and a PH probe, the collecting pipe is fixed at the bile outlet, and the PH probe is placed at the bottom of the inner wall of the collecting pipe and is used for being connected with the upper computer.

In one embodiment, the bile collector further comprises a luer head and a luer cap, the collecting tube is provided with a detection port, the luer head is arranged at the detection port, the PH probe is connected with the upper computer through the luer head, and the luer cap is arranged at the luer head.

A bile information acquisition method is realized based on the bile information acquisition device, and the method comprises the following steps:

obtaining a bile droplet signal monitored by the titration sensor;

calculating to obtain the volume of the bile liquid drop according to preset parameters of the liquid drop generator;

counting the bile liquid drops according to the bile liquid drop signals to obtain the number of the bile liquid drops;

and calculating to obtain an information acquisition result according to the bile liquid drop volume and the bile liquid drop number and displaying the information acquisition result.

In one embodiment, the calculating and displaying an information acquisition result according to the bile droplet volume and the bile droplet number includes:

obtaining and displaying a change trend chart of the number of the bile drops in unit time according to the number of the bile drops;

obtaining and displaying a change trend graph of the total number of the bile liquid drops according to the number of the bile liquid drops;

obtaining and displaying a graph of the amount change trend of the inner container juice in unit time according to the bile droplet volume and the bile droplet number;

and obtaining and displaying a change trend chart of the total bile generation amount according to the bile droplet volume and the bile droplet number.

In one embodiment, after acquiring the bile droplet signal monitored by the titration sensor, the method further comprises:

and when the bile liquid drop monitoring time reaches a set time threshold, sending a timing reminding warning signal, and timing and resetting.

In one embodiment, after counting the number of bile drops according to the bile drop signal and obtaining the number of bile drop drops, the method further includes:

and when the dropping number of the bile liquid drops reaches a set dropping number threshold value, sending a quantitative reminding warning signal, and carrying out metering zero clearing.

The utility model provides a bile information acquisition device, realizes based on foretell bile monitoring facilities, includes:

the signal acquisition module is used for acquiring a bile droplet signal monitored by the titration sensor;

the calculation module is used for calculating the bile liquid drop volume according to preset liquid drop generator parameters;

the counting module is used for counting the bile liquid drops according to the bile liquid drop signals to obtain the number of the bile liquid drops;

and the display module is used for calculating to obtain an information acquisition result according to the bile liquid drop volume and the bile liquid drop number and displaying the information acquisition result.

A bile information acquisition system comprises an upper computer and bile information acquisition equipment in any embodiment, wherein the upper computer is used for carrying out bile monitoring according to the method.

Above-mentioned bile information acquisition equipment, method, device and system, the bile of secreting the liver is leading-in to the liquid drop generator through the bile duct, generates the bile liquid drop through the liquid drop generator to use and titrate the sensor and turn into digital signal with the bile liquid drop and realize the automatic acquisition to the bile liquid drop, whole monitoring process need not artifical intervention, labour saving and time saving.

Drawings

In order to more clearly illustrate the technical solutions in the embodiments or the conventional technologies of the present application, the drawings used in the descriptions of the embodiments or the conventional technologies will be briefly introduced below, it is obvious that the drawings in the following descriptions are only some embodiments of the present application, and for those skilled in the art, other drawings can be obtained according to the drawings without creative efforts.

FIG. 1 is a schematic diagram of a bile information collection device according to an embodiment;

FIGS. 2-3 are schematic diagrams of the construction of a titration sensor in one embodiment;

FIGS. 4-5 are schematic diagrams of the structure of a bile duct and a droplet generator in one embodiment;

FIGS. 6-7 are schematic views of a bile collector according to an embodiment;

FIG. 8 is a schematic flow chart illustrating a bile information collection method according to an embodiment;

FIG. 9 is a schematic flow chart illustrating a bile information collection method according to another embodiment;

FIG. 10 is a graph showing the change of the number of bile drops per hour;

FIG. 11 is a graph showing the trend of the total number of bile droplets;

FIG. 12 is a graph showing the change tendency of bile production per hour;

FIG. 13 is a graph showing the trend of the total bile production;

FIG. 14 is a block diagram of a bile information collection device according to an embodiment;

FIG. 15 is a block diagram of a bile information collection system according to an embodiment;

fig. 16 is a flow chart of bile information collection in one embodiment.

Description of reference numerals: 1-bile duct, 2-liquid drop generator, 3-titration sensor, 4-bile collector, 21-bile inlet segment, 22-bile dropping tube, 221-bile outlet, 222-first screw thread, 31-infrared emission end, 32-infrared receiving end, 33-signal interface, 34-button, 41-collection tube, 42-second screw thread, 43-luer head and 44-luer cap.

Detailed Description

To facilitate an understanding of the present application, the present application will now be described more fully with reference to the accompanying drawings. Embodiments of the present application are set forth in the accompanying drawings. This application may, however, be embodied in many different forms and should not be construed as limited to the embodiments set forth herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete.

It will be understood that, as used herein, the terms "first," "second," and the like may be used herein to describe various elements, but these elements are not limited by these terms. These terms are only used to distinguish one element from another.

Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this application belongs. The terminology used herein in the description of the present application is for the purpose of describing particular embodiments only and is not intended to be limiting of the application.

It will be understood that when an element is referred to as being "connected" to another element, it can be directly connected to the other element or be connected to the other element through intervening elements. Further, "connection" in the following embodiments is understood to mean "electrical connection", "communication connection", or the like, if there is a transfer of electrical signals or data between the connected objects.

The application provides a device, a method, a device and a system for monitoring secretion of an isolated organ in an organ perfusion process, so that medical staff can evaluate whether the organ is suitable for transplantation or not according to the monitoring result obtained by the device, the method, the device and the system and provide necessary data support for subsequent operations. It will be appreciated that for organs other than the liver, the present application may be used to monitor other fluids leaked or secreted from the isolated organ during perfusion. For example, the organ may be a kidney and the fluid may be urine.

In one embodiment, as shown in fig. 1, a bile information collecting device is provided, comprising a bile duct 1, a droplet generator 2, a titration sensor 3 and a bile collector 4. Wherein the bile duct 1 is used for leading bile from the bile duct into the liquid drop generator 2; the liquid drop generator 2 is connected with the bile duct 1 and is used for generating bile liquid drops so that the bile drops into the bile collector 4; the titration sensor 3 is arranged on the liquid drop generator 2 and is also used for connecting an upper computer; the titration sensor 3 is used for detecting the bile liquid drops passing through and generating corresponding bile liquid drop signals to be sent to an upper computer; the bile collector 4 is connected to the droplet generator 2 for collecting bile droplets dripping from the droplet generator 2.

Specifically, one end of the bile duct 1 is connected with the bile duct outlet of the liver, and the other end is connected with the liquid drop generator 2. The bile duct 1 can be a hollow duct with elastic wall, and is fixed on the liquid drop generator 2 by utilizing the elasticity of the bile duct; or a hollow pipe without elasticity, and the liquid drop generator 2 is fixed by a buckle. After the bile duct 1 is filled with bile, the newly introduced bile squeezes the bile to generate bile droplets in the droplet generator 2, and the droplets are dropped. The titration sensor 3 fixed on the liquid drop generator 2 detects the passing bile liquid drops, generates corresponding bile liquid drop signals and sends the signals to the upper computer. The bile droplets continue to drip down to a bile collector 4 connected to the droplet generator. The bile collector 4 may be fixed to the droplet generator 2 by means of a screw, snap, slide or the like connection.

As shown in fig. 2-3, the titration sensor 3 includes a transmitting end 31, a receiving end 32, and a signal interface 33. Preferably, the titration sensor 3 can monitor the bile droplet signal by infrared light, wherein the emitting end 31 is used for emitting infrared light, the receiving end 32 is used for receiving the infrared light emitted by the emitting end 31, and the signal interface 33 is used for connecting an upper computer. The titration sensor 3 and the drop generator 2 may be fixed by a screw connection, a snap connection, or other known connection. Taking a spring snap connection as an example, the emitting end 31 can be designed as a movable part and connected with a spring, a button 34 is designed outside the titration sensor, the button 34 is pressed, the spring is compressed to drive the emitting end 31 to move outwards, so that the titration sensor 3 can be sleeved on the droplet generator 2, after the button 34 is fixed, the emitting end moves inwards under the action of the spring to clamp the droplet generator 2. The signal interface 33 may be a foldable USB (Universal Serial Bus) interface, directly connected to the upper computer, or a non-foldable USB interface, connected to the upper computer through a lead, or a wireless interface, and sends the bile droplet signal to the upper computer through a wireless signal. The signal interface 33 can be used as a power supply connector of the titration sensor 3 and connected with an upper computer to obtain the electric quantity required by work; a battery module may also be provided in titration sensor 3 to supply power. When no bile drops, the receiving end 32 receives the infrared light emitted by the emitting end 31; when bile drops drop, at the moment when the bile drops pass through the infrared light transmission channel, infrared light emitted by the emitting end 32 is scattered due to the drops, the intensity of the infrared light received by the receiving end 32 suddenly drops, and a drop signal is sent to an upper computer through the signal interface 33.

Above-mentioned bile information acquisition equipment imports liquid drop generator 2 with the bile of liver secretion through bile duct 1, generates the bile liquid drop through liquid drop generator 2 to use titration sensor 3 to turn into the bile liquid drop digital signal and realize the automatic acquisition to the bile liquid drop, for medical personnel provide the basis that the isolated organ function was judged, whole collection process need not artifical intervention, labour saving and time saving. Between four component parts such as liquid drop generater 2, bile duct 1, titration sensor 3 and bile collector 4, all adopt detachable mode to connect, be convenient for change single part, be favorable to practicing thrift the cost.

In one embodiment, as shown in fig. 4-5, the droplet generator 2 comprises a bile inlet section 21 and a bile dripping pipe 22, the bile inlet section 21 penetrates and extends into the bile dripping pipe 22, and a bile outlet 221 is formed at the bottom of the bile dripping pipe 22. The bile inlet section 21 is connected with the bile duct 1, and the bile collector is arranged at the bile outlet 221.

Specifically, the bile inlet section 21 is a hollow pipe, one end of which is connected to the bile duct 1, and the other end of which penetrates and extends into the bile dripping pipe 22, so that the bile can form liquid drops to pass through the infrared light transmission channel without being attached to the side wall surface. Preferably, the bile inlet section 21 is a glass capillary tube, one end of which is wrapped by the bile duct 1 and the other end of which penetrates and extends into the bile drip tube 22. The bile dripping pipe 22 is provided with a bile outlet 221 at the side opposite to the bile inlet section 21, and the bile liquid can enter the bile collector 4 through the bile outlet 221. Preferably, the bile outlet 221 is the same as or slightly smaller than the bile dripping pipe 22, so as to ensure that the bile drops do not adhere to the side wall of the bile dripping pipe 22 and directly reach the bile collector 4. Preferably, a buckle for fixing the bile information acquisition device can be installed on the sleeve bag of the perfusion device to ensure that the bile drip tube is vertically placed. Near the bile outlet 221, the outer surface of the bile drip tube 22 is designed with a first thread 222 for connection to the bile collector 4.

In the embodiment, the bile inlet section 21 penetrating through and extending into the bile dripping pipe 22 is arranged, so that the liquid drops form liquid drops passing through an infrared light transmission channel under the condition that the bile liquid drops are not attached to the side wall surface, and the accuracy of measurement of the titration sensor 3 is improved; through designing bile outlet 221, make the bile liquid drop directly drip into bile collector 4, bile liquid drop is not stained with at whole dripping in-process and attaches bile drip pipe 2 promptly, makes bile drip pipe 2 can used repeatedly, is favorable to practicing thrift the cost.

In one embodiment, as shown in fig. 6, the bile collector 4 comprises a collecting tube 41 and a PH probe, the collecting tube 41 is fixed to the bile outlet 221 of the droplet generator 2, and the PH probe is placed at the bottom of the inner wall of the collecting tube 41 and is used for connecting an upper computer.

Specifically, the opening of collecting pipe 41 is designed with second screw thread 42 for the first screw thread 222 near the bile outlet is connected, and the PH probe is placed in collecting pipe 41 inner wall bottom for measure the PH of the bile liquid drop in reaching bile collector 4, and send the PH measurement result to the host computer. The connection mode of the PH probe and the upper computer can be wired connection or wireless connection. When the bile drops reach the collecting pipe 41, the PH probe arranged at the bottom of the collecting pipe 41 contacts the bile, the PH value of the bile is measured, and the PH value measurement result is sent to an upper computer through a signal interface.

In this embodiment, the PH value of bile in the bile collector 4 is measured in real time by using a PH probe, and the measurement result is sent to an upper computer, which is helpful for more accurate judgment of the metabolic function of perfused liver.

In one embodiment, referring to fig. 6-7, the bile collector 4 further comprises a luer 43 and a luer cap 44, the collection tube 41 is provided with a detection port, the luer 43 is disposed at the detection port, the PH probe is connected with the upper computer through the luer 43, and the luer cap 44 is disposed at the luer 43.

Luer tip 43 is a standardized micro-scale non-invasive junction that is widely used in medical and laboratory instruments. A luer cap 44 is typically used to protect the luer tip 43. Specifically, a detection port may be formed in the bottom of the collection tube 41, the luer head 43 may be disposed in the detection port, and the PH probe may be disposed in the luer head 43 and extend into the bottom of the collection tube 41, so as to measure the PH of the bile droplets reaching the bile collector 4, and send the PH measurement result to the upper computer.

In this embodiment, because the function is oozed to the nothing of luer head 43, pull out the seepage that the PH probe can not arouse the bile, be convenient for carry out the change of PH probe, be favorable to practicing thrift the cost.

In one embodiment, a bile information collecting method is provided, which is implemented based on the above-mentioned bile information collecting device, as shown in fig. 5, and the method includes:

step S110: and acquiring a bile droplet signal monitored by the titration sensor.

Preferably, the titration sensor may monitor the bile droplet signal by infrared light. When bile liquid drops drop, infrared light emitted by the emitting end of the titration sensor is scattered due to the bile liquid drops at the moment when the bile liquid drops pass through the infrared light transmission channel, the intensity of the infrared light received by the receiving end suddenly drops, and a liquid drop signal is sent to an upper computer through a signal interface of the titration sensor. The signal interface can be a folding USB interface, and the host computer is connected directly to the signal interface, also can be a non-folding USB interface, connects the host computer through the lead wire, can also be a wireless interface, sends bile liquid drop signal to the host computer through wireless signal.

Step S120: and calculating to obtain the bile liquid drop volume according to preset liquid drop generator parameters.

In particular, the drop generator parameters refer to the shape, size, material, etc. of the drop outlet of the drop generator. The volume of a bile droplet refers to the volume of a droplet of bile that is dropped from the droplet generator. A drop generator parameter setting window may be designed on the display interface and a system default is preset, and when the user does not set the parameters, the drop generator parameters are considered to be the default. The volume of the bile liquid drop can be calculated by adopting a formula, and can also be calculated by a titration experiment. The bile droplet volume can be calculated in real time according to preset droplet generator parameters and a surface tension correlation formula. Or according to different liquid drop generator parameters, calculating the volume of the bile liquid drop, generating a 'liquid drop generator parameter-liquid drop volume' comparison table according to the calculation result, storing the comparison table into an upper computer, and directly calling a corresponding liquid drop volume result through a preset liquid drop generator parameter when bile information is acquired.

Step S130: and counting the bile droplets according to the bile droplet signals to obtain the number of the bile droplets.

When the bile liquid drops pass through the titration sensor, the titration sensor detects bile liquid drop signals and sends the bile liquid drop signals to the upper computer, the upper computer counts the bile liquid drops according to the received bile liquid drop signals, and the latest liquid drop number obtained by counting is the current bile liquid drop number.

Step S140: and calculating according to the bile liquid drop volume and the bile liquid drop number to obtain and display an information acquisition result.

Specifically, the information acquisition result includes the number of bile droplet drops and the bile production amount. Wherein, the product of the bile droplet volume and the current bile droplet number is the current bile yield. The display mode of the acquired information result can be digital, graph or signal lamp.

Above-mentioned bile information acquisition method, through obtaining the bile liquid drop signal that titration sensor monitored and count the liquid drop signal, can realize the automatic counting of bile liquid drop, through the calculation to bile liquid drop volume, can direct output bile liquid drop total amount result, for medical personnel provide the basis that the isolated organ function was judged, whole collection process need not artifical intervention, labour saving and time saving. The acquired information result is displayed clearly, and the use convenience can be improved.

In one embodiment, as shown in fig. 6, step S140 includes step S141 to step S144.

Step S141: and obtaining and displaying a curve of the change trend of the number of the bile juice drops in unit time according to the number of the bile drops. Specifically, the unit time is a certain time period as a unit, and may be one second, one minute, or one hour. Fig. 10 is a graph showing the change trend of the number of bile drops per hour.

Step S142: and obtaining and displaying a trend chart of the total number of the bile droplets according to the number of the bile droplets. The total number of bile drops refers to the cumulative number of bile drops in a certain period of time. Fig. 11 is a graph showing the trend of the total number of bile droplets.

Step S143: and obtaining and displaying a graph of the change trend of the inner container juice yield in unit time according to the bile liquid drop volume and the bile liquid drop number. Specifically, the unit time is a certain time period as a unit, and may be one second, one minute, or one hour. The bile production amount is the volume of bile produced per unit time. Fig. 12 is a graph showing the change tendency of the bile production amount per hour.

Step S144: and obtaining and displaying a change trend chart of the total bile generation amount according to the bile droplet volume and the bile droplet number. The total bile production refers to the cumulative bile production over a certain period of time. Fig. 13 is a graph showing the trend of the total bile production.

The above four trend graphs can be displayed simultaneously, or one or more trend graphs can be selected for display according to the user requirements. Specifically, display options can be designed on the display interface, and when the options are displayed when the user checks, a corresponding trend graph is displayed. Preferably, a reference line can be added in the trend graph, and when the calculated information acquisition result exceeds the range of the reference line, the exceeding part is highlighted, so that the judgment of a user is facilitated.

In this embodiment, through the demonstration of multiple trend graph, can help medical personnel obtain the bile secretion volume information of pouring into the liver directly perceivedly, be favorable to medical personnel to judge the metabolic function of pouring into the liver fast.

In one embodiment, a bile collector in a bile information acquisition device includes a collection tube and a PH probe, the method further comprising: and obtaining and displaying a pH value change trend graph of the bile in unit time according to a pH value measurement result sent by the pH probe.

The unit time is the same as that in the previous embodiment and is not described herein again. And after the bile liquid drops reach the collecting pipe, a PH probe arranged at the bottom of the collecting pipe contacts the bile, the PH value of the bile is measured, and the PH value measurement result is sent to an upper computer through a signal interface. Specifically, a PH change trend graph display option may be designed on the display interface, and the PH change trend graph is displayed when the option is displayed when the user checks. Preferably, a reference line can be added in the trend graph, and when the calculated information acquisition result exceeds the range of the reference line, the exceeding part is highlighted, so that the judgment of a user is facilitated.

In this embodiment, through measuring bile pH value and showing bile pH value variation trend graph in unit time, help carrying out more accurate judgement to the metabolic function of pouring into the liver.

In one embodiment, with continued reference to fig. 6, after the step of acquiring a bile droplet signal monitored by the titration sensor, the method further comprises a step S150.

Step S150: and when the bile liquid drop monitoring time reaches a set time threshold, sending a timing reminding warning signal, and timing and resetting.

Specifically, a time threshold setting window may be designed on the display interface, and when the user does not set the time threshold, the default time threshold is infinity, that is, the timing reminding function is not started. The unit of the time threshold may be hours, minutes or seconds, which is selected by the user. And when the set time threshold is reached, sending a timing reminding warning signal, timing and resetting, and starting timing of the next round. Specifically, the timing can be carried out through a timer, and a timing result is uploaded to an upper computer; the upper computer can also be used for timing. The timing warning signal can be sound, light or combination of sound and light, and can also be other known warning signal expression forms.

In the embodiment, the timing reminding function is set, so that medical staff can be reminded to pay attention to bile information acquisition results at regular time when needed, and the increase of workload caused by long-time observation is avoided.

In one embodiment, referring to fig. 6, after the step of counting bile droplets according to the bile droplet signal to obtain the number of bile droplet droplets, the method further comprises:

step S160: and when the dropping number of the bile liquid drops reaches a set dropping number threshold value, sending a quantitative reminding warning signal, and carrying out metering zero clearing.

Specifically, a drop number threshold setting window may be designed on the display interface, and when the user does not set the drop number threshold, the default drop number threshold is infinite, that is, the quantitative reminding function is not started. The drop number threshold set by the user can be the drop number or the total volume of the drop volume, and is selected by the user, and when the threshold set by the user is the total volume of the drop volume, the volume of the bile drop obtained by pre-calculation is converted into the drop number of the bile drop. And when the set drop number threshold is reached, sending a quantitative reminding warning signal, carrying out zero clearing on the measurement, and starting the next round of measurement. Specifically, a counter specially used for counting can be arranged, and a counting result is uploaded to an upper computer after counting; counting can also be realized through the counting function of the upper computer. The quantitative warning signal can be sound, light or combination of sound and light, and can also be other known warning signal expression forms. The user may set the drop count threshold to a value related to the volume of the bile collector, at which time the quantitative alert signal may be used to alert the user to replace the bile collector.

In this embodiment, through setting up the ration and reminding the function, can remind medical staff to carry out the change of bile collector automatically, avoid observing for a long time and bring the increase of work load.

In one embodiment, with continued reference to fig. 6, the method may also include both step S150 and step S160.

Step S150: when the bile liquid drop monitoring time reaches a set time threshold, sending a timing reminding warning signal, and timing and resetting;

Specifically, a time threshold setting window and a drop number threshold setting window may be designed on the display interface. When the user does not set the threshold, the default threshold is infinite, that is, the timing or quantitative reminding function is not started. The unit of the time threshold may be hours, minutes or seconds, which is selected by the user. The drop number threshold set by the user can be the drop number or the total volume of the drop volume, and is selected by the user, and when the threshold set by the user is the total volume of the drop volume, the volume of the bile drop obtained by pre-calculation is converted into the drop number of the bile drop. The user may set the drop count threshold to a value related to the volume of the bile collector, at which time the quantitative alert signal may be used to alert the user to replace the bile collector. When the set time threshold is reached, sending a timing reminding warning signal, timing and resetting, and starting timing of the next round; and when the set drop number threshold is reached, sending a quantitative reminding warning signal, carrying out zero clearing on the measurement, and starting the next round of measurement. The timing or quantitative warning signal can be sound, light or combination of sound and light, and can also be other known warning signal expression forms.

In the embodiment, the timing and quantitative reminding functions are arranged, so that medical staff can be reminded to pay attention to bile information acquisition results at regular time when needed, the medical staff can be reminded to replace the bile collector automatically, and the increase of workload caused by long-time observation is avoided.

It should be understood that although the various steps in the flowcharts of fig. 8-9 are shown in order as indicated by the arrows, the steps are not necessarily performed in order as indicated by the arrows. The steps are not performed in the exact order shown and described, and may be performed in other orders, unless explicitly stated otherwise. Moreover, at least some of the steps in fig. 8-9 may include multiple steps or multiple stages, which are not necessarily performed at the same time, but may be performed at different times, which are not necessarily performed in sequence, but may be performed in turn or alternately with other steps or at least some of the other steps or stages.

In one embodiment, as shown in fig. 14, a bile information collecting device is provided, which is implemented based on the bile monitoring apparatus described above, and includes a signal acquiring module 210, a calculating module 220, a counting module 230, and a display module 240.

The signal acquisition module 210 is configured to acquire a bile droplet signal monitored by the titration sensor; the calculation module 220 is used for calculating the bile liquid drop volume according to preset liquid drop generator parameters; the counting module 230 is configured to count bile droplets according to the bile droplet signal to obtain a number of the bile droplets; the display module 240 is used for calculating and displaying an information acquisition result according to the bile droplet volume and the bile droplet number.

Specifically, the signal acquisition module is in signal connection with the titration sensor and is used for acquiring a bile droplet signal monitored by the titration sensor. The calculation module is used for calculating the bile liquid drop volume according to preset liquid drop generator parameters. The volume of the bile liquid drop can be calculated by adopting a formula, and can also be calculated by a titration experiment. The calculation of the bile droplet volume may be performed according to preset droplet generator parameters and surface tension related formulas. Or according to different liquid drop generator parameters, calculating the volume of the bile liquid drop, generating a 'liquid drop generator parameter-liquid drop volume' comparison table according to the calculation result, storing the comparison table into an upper computer, and directly calling a corresponding liquid drop volume result through a preset liquid drop generator parameter when bile information is acquired. The counting module is used for counting the bile liquid drops according to the bile liquid drop signals acquired by the signal acquisition module to obtain the number of the bile liquid drops. And the display module is used for calculating to obtain and display an information acquisition result according to the bile liquid drop volume and the bile liquid drop number. Specifically, the information acquisition result includes the number of bile droplet drops and the bile production amount. Wherein the product of the bile droplet volume and the current bile droplet number is the current bile yield. The display mode of the acquired information result can be digital, graph or signal lamp.

Above-mentioned bile information acquisition device acquires bile liquid drop signal through the signal transmission module, counts liquid drop signal through the count module, can realize the automatic counting of bile liquid drop, through calculation module to bile liquid drop volume's calculation, can directly obtain bile liquid drop total amount result, for medical personnel provide the basis that separation organ function judged, whole collection process need not artifical intervention, labour saving and time saving. The acquired information result is displayed through the display module, so that the information acquisition device is clear at a glance and can improve the use convenience.

In one embodiment, the bile collector in the bile information collecting device comprises a collecting pipe and a PH probe, and the signal acquiring module 210 is further configured to acquire a PH value of the bile droplet detected by the PH probe; the display module is also used for obtaining and displaying a bile pH value variation trend graph in unit time according to the pH value measurement result sent by the pH probe.

In this embodiment, acquire bile pH value through the signal acquisition module to bile pH value variation trend graph shows in the unit time through the display module, helps carrying out more accurate judgement to the metabolic function of pouring into the liver.

For specific limitations of the bile information collection device, reference may be made to the above limitations of the bile information collection method, which are not described herein again. The modules in the bile information acquisition device can be wholly or partially realized by software, hardware and a combination thereof. The modules can be embedded in a hardware form or independent from a processor in the computer device, and can also be stored in a memory in the computer device in a software form, so that the processor can call and execute operations corresponding to the modules. It should be noted that, in the embodiment of the present application, the division of the module is schematic, and is only one logic function division, and there may be another division manner in actual implementation.

In one embodiment, as shown in fig. 15, a bile information collecting system is provided, which includes an upper computer 300 and the bile information collecting apparatus 400, wherein the upper computer is configured to perform bile monitoring according to the method described above.

Specifically, the bile information collecting device 400 is used for acquiring a bile droplet signal, is connected with the upper computer 300 through a signal interface, and sends the bile droplet signal to the upper computer 300. The upper computer 300 counts and calculates according to the received bile droplet signal, and displays the result.

Above-mentioned bile information collection system acquires bile liquid drop signal through bile information collection equipment, realizes the automatic counting of bile liquid drop through the host computer to calculate bile liquid drop total amount result, for medical personnel provide the basis that the isolated organ function was judged, whole collection process need not artifical intervention, labour saving and time saving. The upper computer displays the acquired information result, so that the information acquisition device is clear at a glance and can improve the use convenience.

In one embodiment, as shown in fig. 16, a flow chart of a bile information collection process is provided. After the collection is started, the titration sensor is cleared, parameters of the liquid drop generator are input, and the bile liquid drop volume is calculated according to the corresponding parameters. The liquid drop generator generates bile liquid drops, when the bile liquid drops pass through the titration sensor, the titration sensor detects bile liquid drop signals and transmits the signals to the upper computer, the upper computer counts the bile liquid drops, and information acquisition results are obtained and displayed through calculation according to the volume of the bile liquid drops and the number of the bile liquid drops. When the drop number threshold or the time threshold set by the user is not null, quantitative or timed reminders are enabled. When the drop number threshold is reached, quantitatively reminding and carrying out metering zero clearing; and when the time threshold is reached, regularly reminding and timing to reset.

The technical features of the above embodiments can be arbitrarily combined, and for the sake of brevity, all possible combinations of the technical features in the above embodiments are not described, but should be considered as the scope of the present specification as long as there is no contradiction between the combinations of the technical features.

The above-mentioned embodiments only express several embodiments of the present application, and the description thereof is more specific and detailed, but not construed as limiting the scope of the invention. It should be noted that, for a person skilled in the art, several variations and modifications can be made without departing from the concept of the present application, which falls within the scope of protection of the present application. Therefore, the protection scope of the present patent shall be subject to the appended claims.

Claims

1. A bile information acquisition device is characterized by comprising a bile duct, a liquid drop generator, a titration sensor and a bile collector,

the bile collector is connected with the titration sensor and is used for collecting bile liquid drops dropping from the liquid drop generator;

the liquid drop generator comprises a bile inlet section and a bile dropping pipe, the bile inlet section penetrates through and extends into the bile dropping pipe, and a bile outlet is formed in the bottom of the bile dropping pipe; the bile inlet section is connected with a bile duct, and the bile collector is arranged at the bile outlet;

the bile dripping pipe is vertically arranged;

the outer surface of the bile dripping pipe is provided with a first thread which is used for connecting the bile collector;

the bile collector comprises a collecting pipe and a PH probe, the collecting pipe is fixed at the bile outlet, and the PH probe is placed at the bottom of the inner wall of the collecting pipe and connected with the upper computer; the PH probe is used for measuring the PH value of the bile in the collecting tube and in contact with the PH probe, and a PH value measuring result is obtained and sent to the upper computer.

2. The bile information collecting apparatus of claim 1, wherein the bile outlet is the same size as or smaller than the bile dripping tube.

3. The bile information collecting device as claimed in claim 1, wherein the bile collector further comprises a luer head and a luer cap, the collecting tube is opened with a detection port, the luer head is disposed at the detection port, the PH probe is connected with the upper computer via the luer head, and the luer cap is disposed at the luer head.

4. A bile information collection method implemented based on the bile information collection device of any one of claims 1 to 3, the method comprising:

obtaining a bile droplet signal monitored by the titration sensor;

and calculating according to the bile liquid drop volume and the bile liquid drop number to obtain and display an information acquisition result.

5. The bile information collection method of claim 4, wherein the calculating and displaying of the information collection result according to the bile droplet volume and the number of the bile droplets comprises:

6. The method for collecting bile information according to claim 4, further comprising, after acquiring the bile droplet signal monitored by the titration sensor:

7. The bile information collection method of claim 4, wherein after counting the number of bile drops according to the bile drop signal and obtaining the number of bile drops, further comprising:

8. A bile information collection device, implemented based on the bile information collection apparatus of any one of claims 1 to 3, comprising:

9. A bile information acquisition system, which is characterized by comprising an upper computer and the bile information acquisition equipment of any one of 1 to 3, wherein the upper computer is used for bile monitoring according to the method of any one of claims 4 to 7.