CN111956371B

CN111956371B - Medium exchange device

Info

Publication number: CN111956371B
Application number: CN202010794048.XA
Authority: CN
Inventors: 翁福清
Original assignee: Chengdu Celano Medical Technology Co ltd
Current assignee: Chengdu Celano Medical Technology Co ltd
Priority date: 2020-08-10
Filing date: 2020-08-10
Publication date: 2024-01-23
Anticipated expiration: 2040-08-10
Also published as: CN111956371A; WO2022033363A1

Abstract

The invention discloses a medium exchange device for exchanging filling medium, comprising: a first cavity and a second cavity; the medium exchange device is provided with an output interface communicated with one end of the first cavity and an input interface communicated with one end of the second cavity; the medium exchange device is provided with a first piston which can slide along the extending direction of the first cavity in the first cavity, and a second piston which can slide along the extending direction of the second cavity in the second cavity; the medium exchange device further comprises a pressure release valve arranged between the second cavity and the input interface, and a medium receiving runner communicated between the pressure release valve and the second cavity.

Description

Medium exchange device

Technical Field

The invention relates to the field of medical equipment, in particular to a medium exchange device.

Background

Heart valve replacement is commonly used to treat severe heart valve lesions, with heart valve prostheses working in place of the diseased valve. Transcatheter implantable heart valve prostheses are of a wide variety of types, one of which is heart valve prostheses with inflatable cuffs, such as U.S. patent No. 2009/0088846.

Chinese patent publication No. CN106794064a discloses that when implanting such a heart valve prosthesis into a body, it is necessary to pre-fill the balloon of the prosthesis with a radiopaque medium so that the balloon position can be determined by angiography. And when the heart valve prosthesis is implanted and in place, it is necessary to exchange the pre-filled radiopaque medium within the implant for a permanent filling medium.

Disclosure of Invention

In view of the needs of the prior art, it is an object of the present invention to provide a media exchange device for exchanging a filling medium.

In order to achieve the above purpose, the invention adopts the following technical scheme:

a media exchange device, the media exchange device comprising: a first cavity and a second cavity;

the medium exchange device is provided with an output interface communicated with one end of the first cavity and an input interface communicated with one end of the second cavity;

the medium exchange device is provided with a first piston which can slide along the extending direction of the first cavity in the first cavity, and a second piston which can slide along the extending direction of the second cavity in the second cavity;

the medium exchange device further comprises a pressure release valve arranged between the second cavity and the input interface, and a medium receiving runner communicated between the pressure release valve and the second cavity.

As a preferred embodiment, the medium receiving flow channel is provided with an adjusting part which is operatively connected to the atmosphere.

As a preferred embodiment, the second chamber has an inlet end on one side of the second piston and an outlet end on the other side of the second piston, the inlet end being in communication with the medium receiving flow passage and the outlet end being in communication with the atmosphere; the moving direction of the second piston towards the outlet end is the same as the pushed direction of the first piston.

As a preferred embodiment, the medium receiving runner includes a straight runner and a turning runner communicated with the straight runner, the turning runner opens into the inlet end of the second cavity, and the straight runner and the turning runner are arranged in the cavity wall corresponding to the second cavity.

As a preferred embodiment, the adjusting part is provided at a turning part of the straight flow passage leading to the turning flow passage.

As a preferred implementation mode, an output pipe is arranged between the first cavity and the output interface, an input pipe is arranged between the pressure release valve and the input interface, and the input pipe and the output pipe are arranged side by side.

As a preferred embodiment, the adjusting part includes a connection end communicating with the second cavity and a connection part detachably connected to the connection end; the connecting part is communicated with the pressure relief valve through a middle pipe.

As a preferred embodiment, the outlet end of the second cavity is provided with a baffle, and the baffle is provided with a hole.

As a preferred embodiment, a pushing member for pushing the first piston to move is disposed at an end of the first cavity away from the input interface, the pushing member includes a handle and an extending rod connected to the handle, the extending rod extends into the first cavity, and the first piston is fixedly disposed at an end of the extending rod.

As a preferred embodiment, the outer wall of the extending rod is provided with a first thread, and the inner wall of the cavity corresponding to the first cavity is provided with a second thread matched with the first thread at one side of the first piston away from the output interface; or, the inner wall of the handle is provided with a first thread, and the outer wall of the cavity corresponding to the first cavity is provided with a second thread matched with the first thread at one side of the first piston away from the output interface.

As a preferable implementation mode, the cavity walls corresponding to the first cavity and the second cavity are made of transparent materials, and the cross-sectional area of the first cavity is equal to that of the second cavity.

As a preferred implementation mode, the first cavity and the second cavity are provided with scale marks on the corresponding cavity walls, and the scale marks on the first cavity are aligned with the scale marks on the second cavity.

As a preferred embodiment, a loading inlet capable of being plugged and opened is arranged on the cavity wall of the first cavity, and the loading inlet is arranged near one end, away from the output interface, of the first cavity.

As a preferred embodiment, a pressure gauge for measuring the output pressure is further communicated between the output interface and the first cavity.

As a preferred embodiment, the pressure of the output medium of the output interface is 16±2ATM, and the opening pressure of the relief valve is 6ATM.

The beneficial effects are that:

in one embodiment of the invention, when the medium exchange device is used for exchanging medium in an implant, the exchange device is communicated with the implant, and a closed pipe cavity is formed between the first piston and the second piston. The first piston is driven to move towards the output interface by the pushing piece, the curing agent in the first cavity flows out, meanwhile, the curing agent pushes the original liquid medium in the implant to flow out to the second cavity through the pressure release valve and the medium receiving flow channel, and the liquid medium received by the second cavity pushes the second piston to move until medium exchange in the implant is completed.

Specific embodiments of the invention are disclosed in detail below with reference to the following description and drawings, indicating the manner in which the principles of the invention may be employed. It should be understood that the embodiments of the invention are not limited in scope thereby.

Features that are described and/or illustrated with respect to one embodiment may be used in the same way or in a similar way in one or more other embodiments in combination with or instead of the features of the other embodiments.

It should be emphasized that the term "comprises/comprising" when used herein is taken to specify the presence of stated features, integers, steps or components but does not preclude the presence or addition of one or more other features, integers, steps or components.

Drawings

In order to more clearly illustrate the embodiments of the invention or the technical solutions of the prior art, the drawings which are used in the description of the embodiments or the prior art will be briefly described, it being obvious that the drawings in the description below are only some embodiments of the invention, and that other drawings can be obtained from these drawings without inventive faculty for a person skilled in the art.

FIG. 1 is a schematic perspective view of a media exchange device according to one embodiment of the present invention;

FIG. 2 is a cross-sectional view and a partial enlarged view of FIG. 1;

FIG. 3 is a schematic illustration of the tick marks of FIG. 1;

FIG. 4 is a cross-sectional view A-A of FIG. 3;

FIG. 5 is a schematic perspective view of a media exchange device according to another embodiment of the present invention;

fig. 6 is a cross-sectional view and a partial enlarged view of fig. 5.

Detailed Description

In order to make the technical solution of the present invention better understood by those skilled in the art, the technical solution of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention, and it is apparent that the described embodiments are only some embodiments of the present invention, not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, shall fall within the scope of the invention.

It will be understood that when an element is referred to as being "disposed on" another element, it can be directly on the other element or intervening elements may also be present. When an element is referred to as being "connected" to another element, it can be directly connected to the other element or intervening elements may also be present. The terms "vertical," "horizontal," "left," "right," and the like are used herein for illustrative purposes only and are not meant to be the only embodiment.

Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. The terminology used herein in the description of the invention is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. The term "and/or" as used herein includes any and all combinations of one or more of the associated listed items.

Referring to fig. 1-4, one embodiment of the present invention provides a media exchange device that may be used, but is not limited to, for exchange of radiopaque media (e.g., contrast media) for heart valve prosthetic implants of the type, and may also be used for exchange of media in other medical environments. For example, the medium exchange device may be used to inject a permanently filled medium (e.g., a curing agent) into a balloon of a heart valve prosthesis while displacing contrast medium within the balloon, although the medium exchange device may also be applied to exchange between two different fluid media.

Specifically, the medium exchange device includes: a first cavity 1; a second cavity 2. Wherein the medium exchange device is provided with an output interface 8 communicating with one end of the first cavity 1. The medium exchange device is provided with a first piston 4 in the first cavity 1, which can slide along the extending direction or the length direction of the first cavity 1. The medium exchange device is provided with an input interface 9 communicating with one end of said second chamber 2. The medium exchange device is provided with a second piston 5 in the second cavity 2, which can slide along the extending direction or the length direction of the second cavity 2.

The media exchange device is further provided with a pressure relief valve 100 and a media receiving flow passage 900. Wherein a pressure relief valve 100 is arranged between the second chamber 2 and the input interface 9. The medium receiving flow passage 900 communicates between the relief valve 100 and the second chamber 2. Wherein the medium receiving flow channel is provided with an adjusting part 600 operatively communicating with the atmosphere.

When the medium exchange in the implant body is carried out, the exchange device is communicated with the implant body, and a closed pipe cavity is formed between the first piston 4 and the second piston 5. The first piston 4 is driven to move towards the output interface 8 by the pushing piece 3, the curing agent in the first cavity 1 flows out from the exchange device towards the prosthesis, meanwhile, the original medium in the implant body is pushed by the curing agent to flow into the second cavity 2 from the implant body towards the exchange device through the pressure release valve 100, and the liquid flowing into the second cavity 2 pushes the second piston 5 until the medium exchange in the implant body is completed.

In this embodiment, the cavity walls corresponding to the first cavity 1 and the second cavity 2 are made of transparent materials. By providing a cavity wall of transparent material, a physician can observe the motion state of the first piston 4 and the second piston 5 through the cavity wall during surgery, so as to determine whether leakage exists in the exchange system formed by the exchange device and the implant.

As shown in fig. 1 and 2, the medium exchange device has a first tube 10 and a second tube 20 in which a first chamber 1 and a second chamber 2 are formed. The first cavity 1 and the second cavity 2 are of an integrated structure. It is understood that the first tube body 10 and the second tube body 20 or the cavity walls of the first cavity 1 and the second cavity 2 are integrally formed structures. The cavity walls of the first cavity 1 and the second cavity 2 may be made of plastic, and further, the first cavity and the second cavity may be injection molded. Of course, the first and second chambers 1 and 2 (the first and second pipes 10 and 20) may be of a split structure, and the first and second pipes 10 and 20 may be connected in a side-by-side manner by a connecting plate or directly bonded side-by-side, or the like.

Of course, in the embodiment of the present application, the medium exchange device may not form the first cavity and the second cavity in the form of a tube, for example, the medium exchange device may have a rectangular block (cuboid) body, and two or more parallel cavities are formed (for example, drilled or integrally formed) on the body, so that two of them may be formed into the first cavity and the second cavity.

In this embodiment, the first cavity 1 and the second cavity 2 are linear cavities. Preferably, the first cavity 1 and the second cavity 2 are both cylindrical cavities. The first and second chambers 1, 2 are arranged side by side (sometimes also referred to as parallel). As shown in fig. 1 and 2, the length direction of the first cavity 1 and the length direction of the second cavity 2 are parallel, and the first cavity 1 and the second cavity 2 (or the first pipe 10 and the second pipe 20) are aligned and co-extended as a whole.

Further, the cross-sectional area of the first cavity 1 is equal to the cross-sectional area of the second cavity 2. Preferably, as shown in fig. 4, the first cavity 1 and the second cavity 2 have the same cross-sectional shape. Therefore, a closed pipe cavity can be formed between the first piston 4 and the second piston 5 in the exchange system, and the movement amounts of the first piston 4 and the second piston 5 are the same under the condition that no leakage occurs, so that whether the system has leakage or not can be judged, and the smooth performance of medium exchange operation is ensured.

Before medium exchange, the first piston 4 and the second piston 5 can be kept flush, so that whether leakage exists in the exchange system can be determined by confirming whether the travelling paths of the first piston 4 and the second piston 5 are consistent in the exchange process, and the method is convenient and quick.

As shown in fig. 3 and 4, in order to make the flush alignment of the first piston 4 and the second piston 5 more accurate, and facilitate the operator to quickly check, and ensure the correct execution and operation of the surgery, the first cavity 1 and the second cavity 2 are provided with graduation marks 18 and 28 on the corresponding cavity walls. And the graduation marks 18 on the first cavity 1 and the graduation marks 28 on the second cavity 2 are mutually aligned. To facilitate alignment of the graduation marks 18 and 28, the graduation marks 18 are disposed on a side of the first tube body 10 adjacent to the second tube body 20, and correspondingly, the graduation marks 28 are disposed on a side of the second tube body 20 adjacent to the first tube body 10. The scale marks of the cavity walls corresponding to the first cavity 1 and the second cavity 2 are arranged side by side and have the same scale, specifically, the scale values and the measuring ranges of the two scale marks are consistent, and the scale marks corresponding to the same scale values are aligned one by one along the direction vertical to the length direction of the cavity. Considering that the cavity wall is made of transparent materials, the scale marks can be the inner wall of the cavity or the outer wall of the cavity, and of course, the scale marks are preferably arranged on the outer wall of the cavity to avoid that the internal medium influences the scale marks to read or pollute the scale marks.

So, can make second piston 5 and first piston 4 be located same scale position through adjusting second piston 5 before exchanging the medium, and then keep the parallel and level to look over whether first piston 4 and second piston 5 synchronous movement and keep with same scale alignment often in exchange process, and then need not to calculate and can acquire whether exchange system takes place to leak fast, guarantee operation timeliness and the accuracy nature of operation.

In this embodiment, in order to facilitate filling of the curing agent, a loading inlet 7 is further provided on the wall of the first cavity 1 corresponding to the cavity. The loading inlet 7 is arranged close to the end of the first chamber 1 into which it is extended. The loading inlet 7 may be provided with a loading plug 71, and plugging and opening of the loading inlet 7 may be achieved by plugging and unplugging the loading plug 71. By arranging the loading inlet 7 to load the curing agent, compared with the mode of sucking the curing agent into the first cavity 1 from the output interface 8 by operating the first piston 4 to move, the loading time of the curing agent can be reduced, the mixing of redundant gas in the curing agent can be avoided, and the gas in the curing agent is discharged without driving the first piston 4 for multiple times, so that the loading process of the curing agent is more convenient and quicker. Of course, in other embodiments, the solution of sucking the curing agent into the first cavity 1 from the output port 8 by pulling the first piston 4 by the pushing member 3 is not excluded, so that the provision of additional openings in the cavity wall can be avoided, and the structure is simpler.

In this embodiment, the other end of the first chamber 1 is extended into a pushing member 3 for pushing the first piston 4 to move. The pusher 3 may push and pull the first piston 4 such that the first piston 4 moves back and forth along the first chamber 1 in the first chamber 1. Specifically, the pushing member 3 includes a handle 31 and an extending rod 32 connected to the handle 31. The projecting rod 32 projects into the first chamber 1. The first piston 4 is fixedly connected to the end of the extension rod 32.

Specifically, to achieve output under high pressure of the medium, the outer wall of the extending rod 32 is provided with a first thread. The inner wall of the first cavity 1 corresponding to the first cavity is provided with a second thread matched with the first thread on one side of the first piston 4 away from the output interface 8. The extending rod 32 can be designed as a threaded screw rod, and an operator can drive the first piston 4 to move by holding the handle 31 and rotating the handle 31, so that high-pressure output of a medium can be realized.

Of course, in another embodiment, the extending rod 32 may extend into the first cavity 1 in a smooth wall surface manner, the extending rod 32 is fixedly connected with the handle 31, a first thread is disposed on an inner wall of the handle 31, a second thread matched with the first thread is disposed on a side, far away from the output interface 8, of a corresponding cavity outer wall of the first cavity 1, the handle 31 is disposed outside an end portion of the first pipe body 10 (i.e., outside a cavity wall of the first cavity 1) through a thread connecting sleeve, and the first thread (internal thread) of the handle 31 is matched with a second thread (external thread) on the cavity outer wall of the first cavity 1 to implement medium output under high pressure by rotating the handle 31.

In other embodiments, the pushing member 3 may also be a push-pull handle 31, the outer wall of the extending rod 32 may be a smooth wall, and the push-pull handle 31 is used to push and pull the first piston 4.

In this embodiment, the second chamber 2 has an inlet end 23 located on one side of the second piston 5 and an outlet end 22 located on the other side of the second piston 5. The inlet end 23 communicates with the media receiving flow passage 900. The entrance end 23 is closer to the handle 31 than the exit end 22. The liquid entering at the inlet end 23 pushes the second piston 5 towards the outlet end 22. The inlet end 23 communicates with the pressure relief valve 100 via a media receiving flow passage 900. The outlet end 22 is in communication with the atmosphere. The direction of movement of the second piston 5 towards the outlet end 22 is the same as the direction in which the first piston 4 is pushed. In particular, the outlet end 22 is provided with a baffle 24, by means of which baffle 24 the range of movement of the second piston 5 can be defined. The baffle plate 24 is provided with a hole 241 penetrating the baffle plate 24. From the hole 241, a rod-shaped member protrudes into the second chamber 2, the position of the second piston 5 can be adjusted, for example, the initial assembly position of the second piston 5. Wherein the baffle 24 may be fixedly welded to the outlet end 22 or snapped onto the outlet end 22.

In this embodiment, the medium receiving flow passage 900 communicates the relief valve 100 with the second chamber 2. The medium receiving flow passage comprises a straight flow passage 92 and a turning flow passage 93 communicated with the straight flow passage 92, the turning flow passage 93 is led to the inlet end 23 of the second cavity 2, and the straight flow passage 92 and the turning flow passage 93 are arranged in the cavity wall of the second cavity 2.

Specifically, a straight runner 92 that communicates the pressure release valve 100 with the second cavity 2 is disposed on a cavity wall of the second cavity 2. The adjusting part 600 is disposed at an end of the straight flow path 92 near one end of the handle 31 (an end far from the pressure release valve 100), so as to facilitate the injection of the liquid into the second chamber 2 and the adjustment of the position of the second piston 5. As shown in fig. 4, the straight runner 92 is disposed side by side with the second cavity 2. The cross-sectional area of the straight flow passage 92 is smaller than that of the second chamber 2, and may be circular. The third chamber arranged in parallel with the first chamber 1 and the second chamber 2 is formed as a straight flow passage 92. The straight runner 92, the first cavity 1 and the second cavity 2 may be an integrally formed structure, for example, injection molding together.

Specifically, the end of the straight flow passage 92 away from the pressure release valve 100 is communicated with the inlet end 23 of the second cavity 2 through a turning channel 93. The turn-around channel 93 is perpendicular to the second cavity 2 and the straight flow channel 92. The adjusting part 600 is provided at the turning part of the straight runner 92 leading to the turning runner 93.

Further, the adjusting portion 600 includes an adjusting hole 6 provided on a channel wall of the folding channel 93, and an adjusting plug 61 is provided corresponding to the adjusting hole 6. Plugging and opening of the adjusting hole 6 is realized by plugging the adjusting plug body 61. The adjusting hole 6 is communicated with the atmosphere after being opened, namely, the pipe cavity between the pressure release valve 100 and the second piston 5 is communicated with the atmosphere, so that liquid can be filled in the pipe cavity of the section, and gas in the pipe cavity is discharged. The opening direction or orientation of the adjustment hole 6 may be perpendicular to or parallel to the length direction (or axial direction) of the second chamber 2. When the adjusting hole 6 is parallel to the length direction of the second cavity 2, the adjusting hole can be distinguished from the loading inlet 7, so that an operator can conveniently distinguish the adjusting hole 6 from the loading inlet 7 (the direction of the opening of the loading inlet 7 in fig. 2 or the direction perpendicular to the length direction of the first cavity 1), and the operator can conveniently recognize the adjusting hole.

In this embodiment, the first cavity 1 is communicated with the output port 8 through an output pipe 81. The pressure release valve 100 is communicated with the input port 9 through an input pipe 91. In order to make the whole structure of the exchange device compact, the output pipe 81 and the input pipe 91 are arranged in parallel. A pressure gauge 82 (for example, a pressure gauge) for measuring output pressure is also connected between the output port 8 and the first cavity 1. In particular, the pressure gauge 82 may be provided on the output pipe 81. The pressure of the closed lumen between the first piston 4 and the second piston 5 during the exchange can be observed by means of the pressure gauge 82. Of course, in other embodiments, the pressure gauge 82 may be disposed between the input interface 9 and the second piston 5, which is not limited in the embodiment of the present application.

In this embodiment, the relief valve 100 has an opening pressure, wherein the opening pressure of the relief valve 100 is greater than atmospheric pressure, and the degree of expansion of the implant can be ensured by providing the relief valve 100. Specifically, the opening pressure is 6ATM. In addition, in the previous step of exhausting air and aligning the second piston 5 with the first piston 4, due to the arrangement of the pressure release valve 100, the liquid input into the straight flow passage 92 can be prevented from being discharged from the pressure release valve, and then the second cavity 2 can be filled by injecting the liquid from the adjusting hole 6 to change the position of the second piston 5.

Referring to fig. 5 and 6, in another embodiment, the adjusting portion 600' includes: a connection end 6 'communicating with the second chamber 2', and a connection portion 61 'detachably connected to the connection end 6'. In this embodiment, the pipeline where the pressure relief valve 100' is located, the first cavity 1 (the first pipe body 10) and the second cavity 2' (the second pipe body 20 ') are not integrated structures, and the pipeline where the pressure relief valve 100' is located can be assembled and disassembled on the main body where the first cavity 1 and the second cavity 2' are located. The input port 9 'is provided on the pressure relief valve 100'.

Specifically, the adjusting portion 600' is a detachable connection structure. The controllable manipulation of the regulating portion 600' to the atmosphere is achieved in a detachable manner. The connecting part 61 'and the relief valve 100 are communicated through an intermediate pipe 92'. Specifically, the connection end 6 'is provided with a luer female connector, and the connection portion 61' is provided with a luer male connector, and the luer female connector and the luer male connector are in threaded connection.

The exchange device according to any of the embodiments above, prior to exchanging the medium (exchange device not in communication with the implant): the first piston 4 and the output interface 8, the input interface 9 and the second piston 5 of the exchange device can be filled with liquid, so that incomplete medium replacement caused by air mixing is avoided; further, pushing the first piston 4 is stopped until the output pressure of the solidifying agent meets a specific exchange requirement, for example, when exchanging the developing solution in the heart valve implant, the output pressure of the solidifying agent is required to be 16±2ATM; finally, the position of the second piston 5 is adjusted to align the second piston 5 with the first piston 4.

Specifically, the solidifying agent is filled between the first piston 4 and the output port 8, and the normal medical fluid (for example, physiological saline) is filled between the input port 9 and the second piston 5. Opening the adjustment hole 6 of the adjustment part 600 or opening the adjustment hole 6 'of the adjustment part 600' can discharge the air in the input channel, facilitating filling of the liquid between the input port 9 and the second piston 5. Closing the adjustment aperture 6 or 6', the input port to the second piston may form a closed lumen.

In view of the above description, it is necessary to adjust the alignment of the first piston 4 and the second piston 5 before the medium exchange is performed, and in particular, it is necessary to adjust the alignment of the second piston 5 with the first piston 4. For the embodiment of fig. 1, 2, the adjustment aperture 6 is opened, and saline is injected and pumped at the adjustment aperture 6, the second piston 5 position is adjusted so that the second piston 5 is aligned with the first piston 4, after which the adjustment aperture 6 is closed. For the embodiment of fig. 5, 6, saline is injected and aspirated from the luer female connector (connection end 6'), the second piston 5 is adjusted to align with the first piston 4, and the luer male connector and luer female connector are connected. Wherein, when it is observed that there is a bubble in the passage between the relief valve 100 or 100' and the second piston 5, it is necessary to suck the physiological saline to eliminate the bubble; alternatively, when the position of the second piston 5 exceeds the position of the first piston 4, the saline needs to be sucked to align the second piston 5 with the first piston 4.

The solidifying agent and the common medical liquid are filled in the lumen of the exchange system, and the volume of the liquid medium is kept unchanged because the liquid is not easy to be compressed under high pressure compared with gas (such as air), thereby being beneficial to judging whether the exchange system, particularly the implant part, has leakage or not during medium exchange.

Any numerical value recited herein includes all values of the lower and upper values that are incremented by one unit from the lower value to the upper value, as long as there is a separation of at least two units between any lower value and any higher value. For example, if it is stated that the number of components or the value of a process variable (e.g., temperature, pressure, time, etc.) is from 1 to 90, preferably from 20 to 80, more preferably from 30 to 70, then the purpose is to explicitly list such values as 15 to 85, 22 to 68, 43 to 51, 30 to 32, etc. in this specification as well. For values less than 1, one unit is suitably considered to be 0.0001, 0.001, 0.01, 0.1. These are merely examples that are intended to be explicitly recited in this description, and all possible combinations of values recited between the lowest value and the highest value are believed to be explicitly stated in the description in a similar manner.

Unless otherwise indicated, all ranges include endpoints and all numbers between endpoints. "about" or "approximately" as used with a range is applicable to both endpoints of the range. Thus, "about 20 to 30" is intended to cover "about 20 to about 30," including at least the indicated endpoints.

All articles and references, including patent applications and publications, disclosed herein are incorporated by reference for all purposes. The term "consisting essentially of …" describing a combination shall include the identified element, ingredient, component or step as well as other elements, ingredients, components or steps that do not substantially affect the essential novel features of the combination. The use of the terms "comprises" or "comprising" to describe combinations of elements, components, or steps herein also contemplates embodiments consisting essentially of such elements, components, or steps. By using the term "may" herein, it is intended that any attribute described as "may" be included is optional.

Multiple elements, components, parts or steps can be provided by a single integrated element, component, part or step. Alternatively, a single integrated element, component, part or step may be divided into separate plural elements, components, parts or steps. The disclosure of "a" or "an" to describe an element, component, section or step is not intended to exclude other elements, components, sections or steps.

It is to be understood that the above description is intended to be illustrative, and not restrictive. Many embodiments and many applications other than the examples provided will be apparent to those of skill in the art upon reading the above description. The scope of the present teachings should, therefore, be determined not with reference to the above description, but instead should be determined with reference to the appended claims, along with the full scope of equivalents to which such claims are entitled. The disclosures of all articles and references, including patent applications and publications, are incorporated herein by reference for the purpose of completeness. The omission of any aspect of the subject matter disclosed herein in the preceding claims is not intended to forego such subject matter, nor should the inventors regard such subject matter as not be considered to be part of the disclosed subject matter.

Claims

1. A media exchange device, the media exchange device comprising: a first cavity and a second cavity;

the medium exchange device also comprises a pressure release valve arranged between the second cavity and the input interface, and a medium receiving runner communicated between the pressure release valve and the second cavity; wherein the medium receiving flow passage is provided with an adjusting part which is in operable communication with the atmosphere; the second cavity is provided with an inlet end positioned at one side of the second piston and an outlet end positioned at the other side of the second piston, the inlet end is communicated with the medium receiving flow passage, and the outlet end is communicated with the atmosphere; the moving direction of the second piston towards the outlet end is the same as the pushed direction of the first piston; the medium receiving runner comprises a straight runner and a turning runner communicated with the straight runner, the turning runner leads to the inlet end of the second cavity, and the straight runner and the turning runner are arranged in the cavity wall corresponding to the second cavity;

when the medium exchange device is used for medium exchange in the implant body, the medium exchange device is communicated with the implant body, a closed pipe cavity is formed between the first piston and the second piston, the first piston is driven to move towards the output interface through the pushing piece, the curing agent in the first cavity flows out from the medium exchange device towards the prosthesis, meanwhile, the curing agent pushes original medium in the implant body to flow into the second cavity from the implant body towards the medium exchange device through the pressure release valve, and liquid flowing into the second cavity pushes the second piston until medium exchange in the implant body is completed.

2. The device of claim 1, wherein the adjustment portion is provided at a turn of the straight flow path leading to the turn flow path.

3. The device of claim 2, wherein an output tube is disposed between the first chamber and the output port, and an input tube is disposed between the pressure relief valve and the input port, the input tube and the output tube being disposed side-by-side.

4. The device of claim 1, wherein the adjustment portion includes a connection end in communication with the second cavity and a connection portion removably connected to the connection end; the connecting part is communicated with the pressure relief valve through a middle pipe.

5. The device of claim 3 or 4, wherein the outlet end of the second chamber is provided with a baffle, and the baffle is provided with a hole.

6. The device of claim 5, wherein an end of the first cavity remote from the input interface is provided with a pushing member for pushing the first piston to move, the pushing member comprises a handle and an extending rod connected with the handle, the extending rod extends into the first cavity, and the first piston is fixedly arranged at the end of the extending rod.

7. The device of claim 6, wherein the outer wall of the extending rod is provided with first threads, and the inner wall of the cavity corresponding to the first cavity is provided with second threads matched with the first threads on one side of the first piston away from the output interface; or, the inner wall of the handle is provided with a first thread, and the outer wall of the cavity corresponding to the first cavity is provided with a second thread matched with the first thread at one side of the first piston away from the output interface.

8. The device of claim 1 or 7, wherein the walls of the first cavity and the second cavity are transparent, and the cross-sectional area of the first cavity is equal to the cross-sectional area of the second cavity.

9. The device of claim 8, wherein the first cavity and the second cavity are each provided with graduation marks on the wall of the corresponding cavity, and the graduation marks on the first cavity are aligned with the graduation marks on the second cavity.

10. The device of claim 1, wherein a closeable open loading inlet is provided in a wall of the first chamber, the loading inlet being disposed proximate an end of the first chamber remote from the input interface.

11. The device of claim 1, wherein a pressure gauge for measuring output pressure is further in communication between the output port and the first chamber.

12. The apparatus of claim 11, wherein the output interface outputs a medium pressure of 16±2ATM and the relief valve opens at a pressure of 6ATM.