CN111929249A - Domestic blood routine detection device of tumour patient - Google Patents

Domestic blood routine detection device of tumour patient Download PDF

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Publication number
CN111929249A
CN111929249A CN202010477554.6A CN202010477554A CN111929249A CN 111929249 A CN111929249 A CN 111929249A CN 202010477554 A CN202010477554 A CN 202010477554A CN 111929249 A CN111929249 A CN 111929249A
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China
Prior art keywords
blood
main controller
data
blood sample
parameter data
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CN202010477554.6A
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Chinese (zh)
Inventor
洪东升
张建华
叶子奇
陈敬
卢晓阳
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First Affiliated Hospital of Zhejiang University School of Medicine
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First Affiliated Hospital of Zhejiang University School of Medicine
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Priority to CN202010477554.6A priority Critical patent/CN111929249A/en
Publication of CN111929249A publication Critical patent/CN111929249A/en
Pending legal-status Critical Current

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Electro-optical investigation, e.g. flow cytometers
    • G01N15/1434Electro-optical investigation, e.g. flow cytometers using an analyser being characterised by its optical arrangement
    • G01N2015/012
    • G01N2015/016
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Electro-optical investigation, e.g. flow cytometers
    • G01N2015/1486Counting the particles

Abstract

The invention provides a household blood routine detection device for a tumor patient, which comprises a case and an end cover, wherein the end cover is movably connected with the case through a hinge, a main controller and a memory are arranged in the case, a control keyboard, a display and a communication module are arranged at the top of the case, and a blood sample detection module and a loudspeaker are arranged on the side surface of the case; the control keyboard is connected with a main controller, and the main controller is respectively connected with the display, the communication module and the loudspeaker; the blood sample detection module comprises a single chip microcomputer, a time sequence controller, a probe assembly, an I/V converter, a filter and an automatic gain circuit which are connected in sequence; the probe assembly comprises a light source drive, a red light LED, an infrared light LED and a photoelectric receiver, the conventional blood detection device is suitable for tumor patients to use at home, is convenient to operate, occupies small space, and can remotely transmit measured data to doctors.

Description

Domestic blood routine detection device of tumour patient
Technical Field
The invention relates to a household blood routine detection device for a tumor patient.
Background
Tumor refers to a new organism formed by local tissue cell proliferation under the action of various tumorigenic factors, because the new organism mostly presents space-occupying block-shaped protrusions, which is also called neoplasm. After chemotherapy, tumor patients need to go to a hospital for blood routine every week, and some patients may not go to the hospital conveniently.
The blood routine refers to an examination for determining the blood condition and disease by observing the number change and morphological distribution of blood cells, and the current blood routine test is completed by machine detection with the development of test modernization and automation. The routine blood test includes red blood cell count (RBC), hemoglobin (Hb), White Blood Cells (WBC), differential white blood cell count (pbc), and Platelets (PLT), and is generally classified into three systems, i.e., red blood cell system, white blood cell system, and platelet system.
Many specific indexes in the blood routine are common sensitive indexes which are sensitive to many pathological changes in the organism, wherein the specific indexes have diagnostic reference values such as white blood cell count, red blood cell count, hemoglobin and platelets, and many patients can be subjected to blood routine examination to perform auxiliary diagnosis when the etiology is unknown. In addition, routine blood tests are common indicators of observed therapeutic effects, medication or withdrawal, continued or discontinued therapy, recurrence or recovery of disease.
The conventional blood detection instrument has the advantages of complex structure, inconvenient operation and large occupied space, and the detection data can not be remotely shared, so the conventional blood detection instrument is not very suitable for patients to independently use at home.
Disclosure of Invention
The invention aims to overcome the defects of the prior art and provides a household blood routine detection device for tumor patients, which is suitable for the tumor patients to use at home, is convenient to operate, occupies small space and can remotely transmit measured data to doctors.
The invention is realized in this way, a kind of tumor patient's domestic blood routine checkout gear, including chassis and end cap, the said end cap passes hinge and chassis swing joint, there are main control unit and memorizer in the said chassis, there are control keyboard, display and communication module on the top of the said chassis, there are blood sample detection module and loudspeaker on the side of the said chassis;
preferably, the control keyboard is connected with a main controller, digital signals generated by the control keyboard are processed by the main controller, the blood sample detection module is connected with a memory, blood parameter data detected by the blood sample detection module are stored in the memory, the memory is connected with the main controller, the blood parameter data in the memory are transmitted to the main controller for processing, the main controller is respectively connected with a display, a communication module and a loudspeaker, the main controller transmits the processed blood parameter data to the display for displaying, the main controller transmits the processed blood parameter data to the communication module for realizing remote data transmission, and the main controller transmits the processed blood parameter data to the loudspeaker for realizing voice broadcast;
preferably, the blood sample detection module comprises a single chip microcomputer, a time sequence controller, a probe assembly, an I/V converter, a filter and an automatic gain circuit which are sequentially connected; the probe assembly comprises a light source driver, a red light LED, an infrared light LED and a photoelectric receiver;
preferably, the single chip microcomputer is connected with the time sequence controller, the single chip microcomputer generates a control signal to drive the time sequence controller to generate a time sequence control signal, and the time sequence control signal drives the light source of the probe assembly to drive, so that the light source drive can alternately drive the red light LED and the infrared light LED to generate light; the blood parameter detection device comprises a red light LED, an infrared light LED, a photoelectric receiver, an I/V converter, a filter, an automatic gain circuit and a singlechip, wherein light rays generated by the red light LED and the infrared light LED are used as measurement signals for detecting a blood sample, the photoelectric receiver is used for receiving the measurement signals penetrating through the blood sample and converting the measurement signals into current signals, the I/V converter is used for receiving the current signals transmitted by the photoelectric receiver and converting the current signals into voltage signals in an equal proportion, the filter is used for receiving the voltage signals transmitted by the I/V converter and carrying out low-pass filtering processing on the voltage signals to eliminate high-frequency noise, and the automatic gain circuit is used for receiving the voltage signals transmitted by the filter, carrying.
Preferably, the front end of the case is provided with a clamping position, the front end of the case cover is provided with a buckle, the buckle is clamped in the clamping position, and the side surface of the case is also provided with a handle.
Preferably, the display is arranged on the surface of the case in an inclined manner of 15 degrees.
Preferably, the communication module comprises a wireless communication module and a wired communication module, the wireless communication module is used for transmitting the blood parameter data to a mobile phone of the user, and the limited communication module is used for transmitting the blood parameter data to an attending doctor of the user.
Preferably, the blood parameter data comprises red blood cell count data, hemoglobin content data, white blood cell count data, platelet count data and differential white blood cell count data.
Preferably, the differential white blood cell count data includes neutrophil count data, eosinophil count data, basophil count data, lymphocyte count data, and monocyte count data.
Another problem to be solved by the present invention is to provide a method for detecting a blood routine detection device, comprising the following steps:
s1, collecting blood of a user through a transparent blood collector with an anticoagulant inside, and sealing the blood collector to obtain a blood sample;
s2, placing the obtained blood sample into a blood sample detection module, wherein a red light LED and an infrared light LED of a probe assembly alternately generate light serving as a measurement signal to irradiate the blood sample, a photoelectric receiver of the probe assembly receives the measurement signal penetrating through the blood sample and converts the measurement signal into a current signal, and the current signal is analyzed and stored in a single chip microcomputer to form blood parameter data after being processed by an I/V converter, a filter and an automatic gain circuit;
s3, the singlechip of the blood sample detection module transmits the blood parameter data to the memory for storage, the main controller calls the blood parameter data in the memory, and the main controller processes the blood parameter data and then displays the data through the display, realizes voice broadcast through the loudspeaker and transmits the data to the user side through the communication module.
Preferably, in S1, the user is an adult and venous blood is taken; the user is a minor and takes peripheral blood.
Preferably, the user in S1 is a tumor patient.
Preferably, the blood weight of the blood sample in S1 is 2-4 ml.
In summary, due to the adoption of the technical scheme, the invention has the beneficial effects that: the device is integrally of a case and end cover structure, so that the device is small in occupied space, convenient to carry and suitable for being used at home; the blood sample detection module comprises a singlechip, a time schedule controller, a probe assembly, an I/V converter, a filter and an automatic gain circuit which are connected in sequence; the probe subassembly includes light source drive, ruddiness LED, infrared light LED and photoelectric receiver for can directly detect through blood sample detection module after the user gathers blood sample, data main control unit after handling through main control unit shows through the display after handling blood parameter data, realize voice broadcast through the speaker, make the patient can audio-visual know blood conventional state, and give the user side (convey patient's doctor promptly) with data transmission through communication module, make things convenient for the real-time physical status who knows the patient of doctor.
Drawings
In order to more clearly illustrate the technical solution of the present invention, the drawings needed to be used in the embodiments will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and it is obvious for those skilled in the art that other drawings can be obtained according to the drawings without creative efforts.
FIG. 1 is a perspective view of the exterior of a conventional blood-detecting device for home use in tumor patients according to the present invention.
Fig. 2 is a schematic block diagram of a blood routine detection device for home use of a tumor patient according to the present invention.
FIG. 3 is a block diagram of a blood sample detection module of a conventional blood detection device for home use in tumor patients according to the present invention.
Detailed Description
The technical solution in the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention.
As shown in fig. 1-3, the present embodiment provides a blood routine detection device for a tumor patient, including a case 1 and an end cap 2, where the end cap 2 is movably connected to the case 1 by a hinge, a main controller 3 and a memory 4 are disposed in the case 1, and a processor chip is integrated in the main controller 3 for processing data. The top of the case 1 is provided with a control keyboard 5, a display 6 and a communication module 7, the side of the case 1 is provided with a blood sample detection module 8 and a loudspeaker 9, and the control keyboard 5 can directly control the detection device to realize detection operation;
the control keyboard 5 is connected with the main controller 3, digital signals generated by the control keyboard 5 are processed by the main controller 5, the blood sample detection module 8 is connected with the memory 4, blood parameter data detected by the blood sample detection module 8 are stored in the memory 4, the memory 4 is connected with the main controller 3, the blood parameter data in the memory 4 are transmitted to the main controller 3 for processing, the main controller 3 is respectively connected with the display 6, the communication module 7 and the loudspeaker 9, the main controller 3 transmits the processed blood parameter data to the display 6 for displaying, the main controller 3 transmits the processed blood parameter data to the communication module 7 for realizing remote data transmission, and the main controller 3 transmits the processed blood parameter data to the loudspeaker 9 for realizing voice broadcasting;
the blood sample detection module 8 comprises a single chip microcomputer 81, a time sequence controller 82, a probe component 83, an I/V converter 84, a filter 85 and an automatic gain circuit 86 which are connected in sequence; the probe assembly 83 comprises a light source drive 831, a red LED832, an infrared LED833 and a photo receiver 834; the blood sample detection module 8 has a space in the middle for receiving a blood sample.
The I/V converter 84 converts the current signal received by the photoreceiver 834 into a voltage signal proportional to the transmitted light intensity, and since the actually detected photocurrent is very small, a small capacitor is connected in parallel in the I/V converter 84 to form an integrating circuit, which can further reduce the input current noise.
The filter 85 is a filter circuit composed of a capacitor, an inductor, and a resistor. The filter can effectively filter the frequency point of the specific frequency in the power line or the frequencies except the frequency point to obtain a power signal of the specific frequency or eliminate the power signal of the specific frequency. By using the frequency selection function of the filter, interference noise can be filtered out or spectrum analysis can be carried out.
The automatic gain circuit 86 is capable of amplifying a voltage signal so as to reduce a change in the output signal level caused by a change in the input signal level.
The timing controller 82 can generate timing control signals, so that the light source drive 831 drives the red light LED832 and the infrared light LED833 to ensure that the red light LED832 and the infrared light LED833 stably and alternately irradiate a blood sample, the detection efficiency is improved, and the LED832 and the infrared light LED833 are driven in a time-sharing manner, so that measurement signals can share the same signal channel to be amplified and filtered without mutual interference, and errors caused by different channel characteristics in dual-channel transmission are avoided.
The single chip microcomputer 81 is connected with the time sequence controller 82, the single chip microcomputer 81 generates a control signal to drive the time sequence controller 82 to generate a time sequence control signal, and the time sequence control signal drives the light source drive 831 of the probe assembly 83, so that the light source drive 831 can alternately drive the red light LED832 and the infrared light LED833 to generate light; the red light LED832 and the infrared light LED833 are used for detecting a blood sample as a measurement signal, the photoelectric receiver 834 is used for receiving the measurement signal transmitted through the blood sample and converting the measurement signal into a current signal, the I/V converter 84 is used for receiving the current signal transmitted by the photoelectric receiver 834 and converting the current signal into a voltage signal in an equal proportion, the filter 85 is used for receiving the voltage signal transmitted by the I/V converter 84 and performing low-pass filtering processing on the voltage signal to eliminate high-frequency noise, the automatic gain circuit 86 is used for receiving the voltage signal transmitted by the filter 85 and performing equal-proportion amplification processing on the voltage signal, and then the voltage signal is transmitted to the single chip microcomputer 81 to be analyzed and stored to form blood parameter data.
The front end of the case 1 is provided with a clamping position 10, the front end of the case cover 2 is provided with a buckle 11, the buckle 1110 is clamped in the clamping position 10, and when the case is not used, the case cover 2 can be buckled on the case 1, so that the case is convenient to store. The side surface of the case 1 is also provided with a handle 13, and the whole case 1 is convenient to carry by holding the handle 13.
The display 6 is arranged on the surface of the case 1 in an inclined manner at an angle of 15 degrees, and the inclined arrangement is convenient for a user to observe.
The communication module 7 comprises a wireless communication module and a wired communication module, is integrated in a shell and is provided with a network interface to realize wired network transmission; and the wireless wifi function is provided. The wireless communication module is used for transmitting the blood parameter data to a mobile phone of a user, and the limited communication module is used for transmitting the blood parameter data to an attending doctor of the user.
The blood parameter data includes red blood cell count data, hemoglobin content data, white blood cell count data, platelet count data, and white blood cell differential count data.
The differential white blood cell count data includes neutrophil count data, eosinophil count data, basophil count data, lymphocyte count data, and monocyte count data.
The detection method of the blood routine detection device comprises the following steps:
s1, collecting blood of a user through a transparent blood collector with an anticoagulant inside, and sealing the blood collector to obtain a blood sample;
s2, placing the obtained blood sample into a blood sample detection module, wherein a red light LED and an infrared light LED of a probe assembly alternately generate light serving as a measurement signal to irradiate the blood sample, a photoelectric receiver of the probe assembly receives the measurement signal penetrating through the blood sample and converts the measurement signal into a current signal, and the current signal is analyzed and stored in a single chip microcomputer to form blood parameter data after being processed by an I/V converter, a filter and an automatic gain circuit;
s3, the singlechip of the blood sample detection module transmits the blood parameter data to the memory for storage, the main controller calls the blood parameter data in the memory, and the main controller processes the blood parameter data and then displays the data through the display, realizes voice broadcast through the loudspeaker and transmits the data to the user side through the communication module.
Taking venous blood if the user is an adult in the S1; the user can take peripheral blood from juveniles, so as to ensure the convenience of blood collection.
In the step S1, the user is a tumor patient who needs routine blood test every week, and the test device of the present invention is particularly suitable.
The blood weight of the blood sample in S1 was 2-4 ml.
In summary, due to the adoption of the technical scheme, the invention has the beneficial effects that: the device is integrally of a case and end cover structure, so that the device is small in occupied space, convenient to carry and suitable for being used at home; the blood sample detection module comprises a singlechip, a time schedule controller, a probe assembly, an I/V converter, a filter and an automatic gain circuit which are connected in sequence; the probe subassembly includes light source drive, ruddiness LED, infrared light LED and photoelectric receiver for can directly detect through blood sample detection module after the user gathers blood sample, data main control unit after handling through main control unit shows through the display after handling blood parameter data, realize voice broadcast through the speaker, make the patient can audio-visual know blood conventional state, and give the user side (convey patient's doctor promptly) with data transmission through communication module, make things convenient for the real-time physical status who knows the patient of doctor.
The foregoing is a preferred embodiment of the present invention, and it should be noted that it would be apparent to those skilled in the art that various modifications and enhancements can be made without departing from the principles of the invention, and such modifications and enhancements are also considered to be within the scope of the invention.

Claims (10)

1. A household blood routine detection device for tumor patients comprises a case and an end cover, wherein the end cover is movably connected with the case through a hinge;
the control keyboard is connected with a main controller, digital signals generated by the control keyboard are processed by the main controller, the blood sample detection module is connected with a memory, blood parameter data detected by the blood sample detection module are stored in the memory, the memory is connected with the main controller, the blood parameter data in the memory are transmitted to the main controller for processing, the main controller is respectively connected with a display, a communication module and a loudspeaker, the main controller transmits the processed blood parameter data to the display for displaying, the main controller transmits the processed blood parameter data to the communication module for realizing remote data transmission, and the main controller transmits the processed blood parameter data to the loudspeaker for realizing voice broadcasting;
the blood sample detection module comprises a single chip microcomputer, a time sequence controller, a probe assembly, an I/V converter, a filter and an automatic gain circuit which are connected in sequence; the probe assembly comprises a light source driver, a red light LED, an infrared light LED and a photoelectric receiver;
the single chip microcomputer is connected with the time sequence controller, generates a control signal to drive the time sequence controller to generate a time sequence control signal, and drives the light source of the probe assembly to drive so that the light source can alternately drive the red light LED and the infrared light LED to generate light; the blood parameter detection device comprises a red light LED, an infrared light LED, a photoelectric receiver, an I/V converter, a filter, an automatic gain circuit and a singlechip, wherein light rays generated by the red light LED and the infrared light LED are used as measurement signals for detecting a blood sample, the photoelectric receiver is used for receiving the measurement signals penetrating through the blood sample and converting the measurement signals into current signals, the I/V converter is used for receiving the current signals transmitted by the photoelectric receiver and converting the current signals into voltage signals in an equal proportion, the filter is used for receiving the voltage signals transmitted by the I/V converter and carrying out low-pass filtering processing on the voltage signals to eliminate high-frequency noise, and the automatic gain circuit is used for receiving the voltage signals transmitted by the filter, carrying.
2. The home-use blood routine detecting device for the patients with tumor according to claim 1, wherein a clamping position is arranged at the front end of the case, a buckle is arranged at the front end of the case cover and clamped in the clamping position, and a handle is further arranged on the side surface of the case.
3. The home-use blood routine testing device of claim 1, wherein said display is disposed at an angle of 15 ° on the surface of said housing.
4. The home-use blood routine testing device for oncology patients of claim 1 wherein the communication module comprises a wireless communication module for transmitting blood parameter data to a user's cell phone and a wired communication module for transmitting blood parameter data to a user's attending physician.
5. A device according to claim 1, wherein said blood parameter data comprises red blood cell count data, hemoglobin content data, white blood cell count data, platelet count data and differential white blood cell count data.
6. The home-use hematology and pathology test device of claim 5, wherein said differential white blood cell count data comprises neutrophil count data, eosinophil count data, basophil count data, lymphocyte count data and monocyte count data.
7. The home-use blood routine testing device for the patients with tumors of claim 1, wherein the testing method of the blood routine testing device comprises the following steps:
s1, collecting blood of a user through a transparent blood collector with an anticoagulant inside, and sealing the blood collector to obtain a blood sample;
s2, placing the obtained blood sample into a blood sample detection module, wherein a red light LED and an infrared light LED of a probe assembly alternately generate light serving as a measurement signal to irradiate the blood sample, a photoelectric receiver of the probe assembly receives the measurement signal penetrating through the blood sample and converts the measurement signal into a current signal, and the current signal is analyzed and stored in a single chip microcomputer to form blood parameter data after being processed by an I/V converter, a filter and an automatic gain circuit;
s3, the singlechip of the blood sample detection module transmits the blood parameter data to the memory for storage, the main controller calls the blood parameter data in the memory, and the main controller processes the blood parameter data and then displays the data through the display, realizes voice broadcast through the loudspeaker and transmits the data to the user side through the communication module.
8. The home-use blood routine test device for tumor patients of claim 1, wherein in S1, the user is an adult and takes venous blood; the user is a minor and takes peripheral blood.
9. The home-use blood routine testing device of claim 1, wherein said S1 user is a tumor patient.
10. The home-use blood routine test device for tumor patients according to claim 1, wherein the blood weight of the blood sample in S1 is 2-4 ml.
CN202010477554.6A 2020-05-29 2020-05-29 Domestic blood routine detection device of tumour patient Pending CN111929249A (en)

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